Stressful Decay Is Okay
J. Biol. Chem.
283: e99929
Enrique Herrero

Current Position: Coordinator of the Yeast Molecular Biology Group at the University of Lleida, Spain
Education: Ph.D., Autonomous University of Barcelona
My group has been involved in yeast biology and genetics for many years; we participated in sequencing of the yeast genome as a member of the European consortium involved in the project, and my team also adapted the tetracycline-regulatable promoters from mammalian to yeast cells. Our present interest focuses on the redox regulation of proteins in response to oxidative stress in yeast, such as monothiol glutaredoxins, enzymes we have characterized which participate in a diversity of redox functions mostly related to iron homeostasis. In this context we came to collaborate with José E. Pérez-Ortín, a molecular biologist at the University of Valencia, who had previously developed the Genomic Run-On (GRO) technology in S. cerevisiae. Pérez-Ortín’s current scientific interest focuses on developing applications for genomic techniques to the study of gene expression in S. cerevisiae. In particular, his group is studying the kinetics of cell responses to environmental stresses at the transcriptional level, taking into account both the regulation of transcription rates and mRNA stability, and thus made a great complement to our work.
Read Dr. Herrero's article on page 17908.