Minireviews:

I Pastan and D FitzGerald

Pseudomonas exotoxin: chimeric toxins
J. Biol. Chem. 1989 264: 15157-15160. [Abstract] [PDF]  

Articles:

MM Heck, WN Hittelman, and WC Earnshaw

In vivo phosphorylation of the 170-kDa form of eukaryotic DNA topoisomerase II. Cell cycle analysis
J. Biol. Chem. 1989 264: 15161-15164. [Abstract] [PDF]  

T Maeda, R Oyama, K Ichihara-Tanaka, F Kimizuka, I Kato, K Titani, and K Sekiguchi

A novel cell adhesive protein engineered by insertion of the Arg-Gly- Asp-Ser tetrapeptide
J. Biol. Chem. 1989 264: 15165-15168. [Abstract] [PDF]  

C Thylen and CK Mathews

Essential role of T4 phage deoxycytidylate hydroxymethylase in a multienzyme complex for deoxyribonucleotide synthesis
J. Biol. Chem. 1989 264: 15169-15172. [Abstract] [PDF]  

C Goddard, ST Arnold, and RL Felsted

High affinity binding of an N-terminal myristoylated p60src peptide
J. Biol. Chem. 1989 264: 15173-15176. [Abstract] [PDF]  

P Andrade-Gordon and S Strickland

Anticoagulant low molecular weight heparin does not enhance the activation of plasminogen by tissue plasminogen activator
J. Biol. Chem. 1989 264: 15177-15181. [Abstract] [PDF]  

C Polvani and R Blostein

Effects of cytoplasmic sodium concentration on the electrogenicity of the sodium pump
J. Biol. Chem. 1989 264: 15182-15185. [Abstract] [PDF]  

T Murayama, Y Nomura, and M Ui

Enhancement of adenosine A2 and prostaglandin E1 receptor-mediated cAMP generation by prior exposure of Swiss 3T3 fibroblasts to Ca2+- mobilizing receptor agonists or phorbol ester. Activation of protein kinase C triggers increases in the receptor density in cell membranes
J. Biol. Chem. 1989 264: 15186-15191. [Abstract] [PDF]  

GE Kass, SK Duddy, GA Moore, and S Orrenius

2,5-Di-(tert-butyl)-1,4-benzohydroquinone rapidly elevates cytosolic Ca2+ concentration by mobilizing the inositol 1,4,5-trisphosphate- sensitive Ca2+ pool
J. Biol. Chem. 1989 264: 15192-15198. [Abstract] [PDF]  

CJ Wallace, P Mascagni, BT Chait, JF Collawn, Y Paterson, AE Proudfoot, and SB Kent

Substitutions engineered by chemical synthesis at three conserved sites in mitochondrial cytochrome c. Thermodynamic and functional consequences
J. Biol. Chem. 1989 264: 15199-15209. [Abstract] [PDF]  

LA Green and RK Liem

Beta-internexin is a microtubule-associated protein identical to the 70- kDa heat-shock cognate protein and the clathrin uncoating ATPase
J. Biol. Chem. 1989 264: 15210-15215. [Abstract] [PDF]  

UP Steinbrecher, M Lougheed, WC Kwan, and M Dirks

Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation
J. Biol. Chem. 1989 264: 15216-15223. [Abstract] [PDF]  

W Rouslin and CW Broge

Regulation of mitochondrial matrix pH and adenosine 5'-triphosphatase activity during ischemia in slow heart-rate hearts. Role of Pi/H+ symport
J. Biol. Chem. 1989 264: 15224-15229. [Abstract] [PDF]  

LA Jelicks and RK Gupta

Multinuclear NMR studies of the Langendorff perfused rat heart
J. Biol. Chem. 1989 264: 15230-15235. [Abstract] [PDF]  

CZ Giam and YL Xu

HTLV-I tax gene product activates transcription via pre-existing cellular factors and cAMP responsive element
J. Biol. Chem. 1989 264: 15236-15241. [Abstract] [PDF]  

CS Taylor and PJ Fleming

Conversion of soluble dopamine beta-hydroxylase to a membrane binding form
J. Biol. Chem. 1989 264: 15242-15246. [Abstract] [PDF]  

GM Mancini, HR de Jonge, H Galjaard, and FW Verheijen

Characterization of a proton-driven carrier for sialic acid in the lysosomal membrane. Evidence for a group-specific transport system for acidic monosaccharides
J. Biol. Chem. 1989 264: 15247-15254. [Abstract] [PDF]  

K Watanabe and T Senshu

Isolation and characterization of cDNA clones encoding rat skeletal muscle peptidylarginine deiminase
J. Biol. Chem. 1989 264: 15255-15260. [Abstract] [PDF]  

MP Chang, J Bramhall, S Graves, B Bonavida, and BJ Wisnieski

Internucleosomal DNA cleavage precedes diphtheria toxin-induced cytolysis. Evidence that cell lysis is not a simple consequence of translation inhibition
J. Biol. Chem. 1989 264: 15261-15267. [Abstract] [PDF]  

ML Howell and KM Blumenthal

Cloning and expression of a synthetic gene for Cerebratulus lacteus neurotoxin B-IV
J. Biol. Chem. 1989 264: 15268-15273. [Abstract] [PDF]  

LM Mertz and RC Pedersen

The kinetics of steroidogenesis activator polypeptide in the rat adrenal cortex. Effects of adrenocorticotropin, cyclic adenosine 3':5'- monophosphate, cycloheximide, and circadian rhythm
J. Biol. Chem. 1989 264: 15274-15279. [Abstract] [PDF]  

K Kobayashi, K Hayashi, and M Sono

Effects of tryptophan and pH on the kinetics of superoxide radical binding to indoleamine 2,3-dioxygenase studied by pulse radiolysis
J. Biol. Chem. 1989 264: 15280-15283. [Abstract] [PDF]  

RD Libby, NS Rotberg, JT Emerson, TC White, GM Yen, SH Friedman, NS Sun, and R Goldowski

The chloride-activated peroxidation of catechol as a mechanistic probe of chloroperoxidase reactions. Competitive activation as evidence for a catalytic chloride binding site on compound I
J. Biol. Chem. 1989 264: 15284-15292. [Abstract] [PDF]  

OP Peoples and AJ Sinskey

Poly-beta-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16. Characterization of the genes encoding beta-ketothiolase and acetoacetyl-CoA reductase
J. Biol. Chem. 1989 264: 15293-15297. [Abstract] [PDF]  

OP Peoples and AJ Sinskey

Poly-beta-hydroxybutyrate (PHB) biosynthesis in Alcaligenes eutrophus H16. Identification and characterization of the PHB polymerase gene (phbC)
J. Biol. Chem. 1989 264: 15298-15303. [Abstract] [PDF]  

CK Chou, TS Su, CM Chang, CP Hu, MY Huang, CS Suen, NW Chou, and LP Ting

Insulin suppresses hepatitis B surface antigen expression in human hepatoma cells
J. Biol. Chem. 1989 264: 15304-15308. [Abstract] [PDF]  

R Croteau and DM Satterwhite

Biosynthesis of monoterpenes. Stereochemical implications of acyclic and monocyclic olefin formation by (+)- and (-)-pinene cyclases from sage
J. Biol. Chem. 1989 264: 15309-15315. [Abstract] [PDF]  

F Tietze, R Seppala, M Renlund, JJ Hopwood, GS Harper, GH Thomas, and WA Gahl

Defective lysosomal egress of free sialic acid (N-acetylneuraminic acid) in fibroblasts of patients with infantile free sialic acid storage disease
J. Biol. Chem. 1989 264: 15316-15322. [Abstract] [PDF]  

C Ra, MH Jouvin, and JP Kinet

Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells
J. Biol. Chem. 1989 264: 15323-15327. [Abstract] [PDF]  

S Harayama and M Rekik

Bacterial aromatic ring-cleavage enzymes are classified into two different gene families
J. Biol. Chem. 1989 264: 15328-15333. [Abstract] [PDF]  

S Tsujino, S Sakoda, R Mizuno, T Kobayashi, T Suzuki, S Kishimoto, S Shanske, S DiMauro, and EA Schon

Structure of the gene encoding the muscle-specific subunit of human phosphoglycerate mutase
J. Biol. Chem. 1989 264: 15334-15337. [Abstract] [PDF]  

RD LaReau and VE Anderson

Lactate dehydrogenase displays absolute stereospecificity in the transfer of the prochiral hydrogen of NADH
J. Biol. Chem. 1989 264: 15338-15343. [Abstract] [PDF]  

GN Pierce and V Panagia

Role of phosphatidylinositol in cardiac sarcolemmal membrane sodium- calcium exchange
J. Biol. Chem. 1989 264: 15344-15350. [Abstract] [PDF]  

TW Cunningham, D Kuppuswamy, and LJ Pike

Treatment of A431 cells with epidermal growth factor (EGF) induces desensitization of EGF-stimulated phosphatidylinositol turnover
J. Biol. Chem. 1989 264: 15351-15356. [Abstract] [PDF]  

LI Szweda and DE Atkinson

Response of rat liver glutaminase to pH. Mediation by phosphate and ammonium ions
J. Biol. Chem. 1989 264: 15357-15360. [Abstract] [PDF]  

R Nemani, JG Ghazarian, B Moorthy, N Wongsurawat, R Strong, and HJ Armbrecht

Phosphorylation of ferredoxin and regulation of renal mitochondrial 25- hydroxyvitamin D-1 alpha-hydroxylase activity in vitro
J. Biol. Chem. 1989 264: 15361-15366. [Abstract] [PDF]  

D Chin and K Brew

Effects of modifying individual amino or carboxyl groups on the affinity of calmodulin for calcineurin
J. Biol. Chem. 1989 264: 15367-15375. [Abstract] [PDF]  

MK al-Shawi, D Parsonage, and AE Senior

Kinetic characterization of the unisite catalytic pathway of seven beta- subunit mutant F1-ATPases from Escherichia coli
J. Biol. Chem. 1989 264: 15376-15383. [Abstract] [PDF]  

RH Cote, GD Nicol, SA Burke, and MD Bownds

Cyclic GMP levels and membrane current during onset, recovery, and light adaptation of the photoresponse of detached frog photoreceptors
J. Biol. Chem. 1989 264: 15384-15391. [Abstract] [PDF]  

ST Ferreira and S Verjovski-Almeida

Fluorescence decay of sarcoplasmic reticulum ATPase. Ligand binding and hydration effects
J. Biol. Chem. 1989 264: 15392-15397. [Abstract] [PDF]  

JC Salerno, Y Xu, MP Osgood, CH Kim, and TE King

Thermodynamic and spectroscopic characteristics of the cytochrome bc1 complex. Role of quinone in the behavior of cytochrome b562
J. Biol. Chem. 1989 264: 15398-15403. [Abstract] [PDF]  

KR Dhariwal, P Washko, WO Hartzell, and M Levine

Ascorbic acid within chromaffin granules. In situ kinetics of norepinephrine biosynthesis
J. Biol. Chem. 1989 264: 15404-15409. [Abstract] [PDF]  

BB Rees, IJ Ropson, and SC Hand

Kinetic properties of hexokinase under near-physiological conditions. Relation to metabolic arrest in Artemia embryos during anoxia
J. Biol. Chem. 1989 264: 15410-15417. [Abstract] [PDF]  

V Gopalan, RH Glew, DP Libell, and JJ DePetro

The dual effects of alcohols on the kinetic properties of guinea pig liver cytosolic beta-glucosidase
J. Biol. Chem. 1989 264: 15418-15422. [Abstract] [PDF]  

A Kamath and K Chakraburtty

Role of yeast elongation factor 3 in the elongation cycle
J. Biol. Chem. 1989 264: 15423-15428. [Abstract] [PDF]  

A Hildebrand, KT Preissner, G Muller-Berghaus, and H Teschemacher

A novel beta-endorphin binding protein. Complement S protein (= vitronectin) exhibits specific non-opioid binding sites for beta- endorphin upon interaction with heparin or surfaces
J. Biol. Chem. 1989 264: 15429-15434. [Abstract] [PDF]  

K Yamamoto and S Kawanishi

Hydroxyl free radical is not the main active species in site-specific DNA damage induced by copper (II) ion and hydrogen peroxide
J. Biol. Chem. 1989 264: 15435-15440. [Abstract] [PDF]  

PL Stein, AJ van Zonneveld, H Pannekoek, and S Strickland

Structural domains of human tissue-type plasminogen activator that confer stimulation by heparin
J. Biol. Chem. 1989 264: 15441-15444. [Abstract] [PDF]  

H Tomoda, Y Kishimoto, and YC Lee

Temperature effect on endocytosis and exocytosis by rabbit alveolar macrophages
J. Biol. Chem. 1989 264: 15445-15450. [Abstract] [PDF]  

ET Lally, EE Golub, IR Kieba, NS Taichman, J Rosenbloom, JC Rosenbloom, CW Gibson, and DR Demuth

Analysis of the Actinobacillus actinomycetemcomitans leukotoxin gene. Delineation of unique features and comparison to homologous toxins
J. Biol. Chem. 1989 264: 15451-15456. [Abstract] [PDF]  

M DiPaola, C Czajkowski, and A Karlin

The sidedness of the COOH terminus of the acetylcholine receptor delta subunit
J. Biol. Chem. 1989 264: 15457-15463. [Abstract] [PDF]  

T Washburn and JE O'Tousa

Molecular defects in Drosophila rhodopsin mutants
J. Biol. Chem. 1989 264: 15464-15466. [Abstract] [PDF]  

SB Masters, RT Miller, MH Chi, FH Chang, B Beiderman, NG Lopez, and HR Bourne

Mutations in the GTP-binding site of GS alpha alter stimulation of adenylyl cyclase
J. Biol. Chem. 1989 264: 15467-15474. [Abstract] [PDF]  

MP Graziano and AG Gilman

Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alpha
J. Biol. Chem. 1989 264: 15475-15482. [Abstract] [PDF]  

EP Bruggemann, UA Germann, MM Gottesman, and I Pastan

Two different regions of P-glycoprotein [corrected] are photoaffinity- labeled by azidopine [published erratum appears in J Biol Chem 1990 Mar 5;265(7):4172]
J. Biol. Chem. 1989 264: 15483-15488. [Abstract] [PDF]  

K Toda, M Tasaka, K Mashima, K Kohno, T Uchida, and I Takeuchi

Structure and expression of elongation factor 2 gene during development of Dictyostelium discoideum
J. Biol. Chem. 1989 264: 15489-15493. [Abstract] [PDF]  

R Chakrabarti, DE Wylie, and SM Schuster

Transfer of monoclonal antibodies into mammalian cells by electroporation
J. Biol. Chem. 1989 264: 15494-15500. [Abstract] [PDF]  

BK McCune and HS Earp

The epidermal growth factor receptor tyrosine kinase in liver epithelial cells. The effect of ligand-dependent changes in cellular location
J. Biol. Chem. 1989 264: 15501-15507. [Abstract] [PDF]  

R Kageyama, GT Merlino, and I Pastan

Nuclear factor ETF specifically stimulates transcription from promoters without a TATA box
J. Biol. Chem. 1989 264: 15508-15514. [Abstract] [PDF]  

SJ Kennel, LJ Foote, R Falcioni, A Sonnenberg, CD Stringer, C Crouse, and ME Hemler

Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6- beta 4 in the integrin superfamily
J. Biol. Chem. 1989 264: 15515-15521. [Abstract] [PDF]  

ME Perry and ME Jones

Orotic aciduria fibroblasts express a labile form of UMP synthase
J. Biol. Chem. 1989 264: 15522-15528. [Abstract] [PDF]  

T Mazzone, K Basheeruddin, and H Duncan

Inhibitors of translation induce low density lipoprotein receptor gene expression in human skin fibroblasts
J. Biol. Chem. 1989 264: 15529-15534. [Abstract] [PDF]  

H Mori, Y Mori, C Ichinose, H Niki, T Ogura, A Kato, and S Hiraga

Purification and characterization of SopA and SopB proteins essential for F plasmid partitioning
J. Biol. Chem. 1989 264: 15535-15541. [Abstract] [PDF]  

RL Matts and R Hurst

Evidence for the association of the heme-regulated eIF-2 alpha kinase with the 90-kDa heat shock protein in rabbit reticulocyte lysate in situ
J. Biol. Chem. 1989 264: 15542-15547. [Abstract] [PDF]  

S Joshi and MJ Pringle

ATP synthase complex from bovine heart mitochondria. Passive H+ conduction through mitochondrial coupling factor 6-depleted F0 complexes
J. Biol. Chem. 1989 264: 15548-15551. [Abstract] [PDF]  

HG Zot and D Puett

An enzymatically active cross-linked complex of calmodulin and rabbit skeletal muscle myosin light chain kinase
J. Biol. Chem. 1989 264: 15552-15555. [Abstract] [PDF]  

SY Wang, MA Roguska, and LJ Gudas

Defective post-translational modification of collagen IV in a mutant F9 teratocarcinoma cell line is associated with delayed differentiation and growth arrest in response to retinoic acid
J. Biol. Chem. 1989 264: 15556-15564. [Abstract] [PDF]  

Y Miyata, E Nishida, S Koyasu, I Yahara, and H Sakai

Protein kinase C-dependent and -independent pathways in the growth factor-induced cytoskeletal reorganization
J. Biol. Chem. 1989 264: 15565-15568. [Abstract] [PDF]  

NA Kocharova, K Hatano, AS Shaskov, YA Knirel, NK Kochetkov, and GB Pier

The structure and serologic distribution of an extracellular neutral polysaccharide from Pseudomonas aeruginosa immunotype 3
J. Biol. Chem. 1989 264: 15569-15573. [Abstract] [PDF]  

SK Moestrup and J Gliemann

Purification of the rat hepatic alpha 2-macroglobulin receptor as an approximately 440-kDa single chain protein
J. Biol. Chem. 1989 264: 15574-15577. [Abstract] [PDF]  

MR MacDonald, J Takeda, CM Rice, and JE Krause

Multiple tachykinins are produced and secreted upon post-translational processing of the three substance P precursor proteins, alpha-, beta-, and gamma-preprotachykinin. Expression of the preprotachykinins in AtT- 20 cells infected with vaccinia virus recombinants
J. Biol. Chem. 1989 264: 15578-15592. [Abstract] [PDF]  

WJ Choi, JL Campbell, CL Kuo, and AY Jong

The Saccharomyces cerevisiae SOC8-1 gene and its relationship to a nucleotide kinase
J. Biol. Chem. 1989 264: 15593-15599. [Abstract] [PDF]  

FS Shen, SF Roberts, and I Lindberg

A putative processing enzyme for proenkephalin in bovine adrenal chromaffin granule membranes. Purification and properties
J. Biol. Chem. 1989 264: 15600-15605. [Abstract] [PDF]  

BJ Bowman, WJ Dschida, T Harris, and EJ Bowman

The vacuolar ATPase of Neurospora crassa contains an F1-like structure
J. Biol. Chem. 1989 264: 15606-15612. [Abstract] [PDF]  

RS Munford and CL Hall

Purification of acyloxyacyl hydrolase, a leukocyte enzyme that removes secondary acyl chains from bacterial lipopolysaccharides
J. Biol. Chem. 1989 264: 15613-15619. [Abstract] [PDF]  

G Lemay, G Waksman, BP Roques, P Crine, and G Boileau

Fusion of a cleavable signal peptide to the ectodomain of neutral endopeptidase (EC 3.4.24.11) results in the secretion of an active enzyme in COS-1 cells
J. Biol. Chem. 1989 264: 15620-15623. [Abstract] [PDF]  

N Takahashi, TR Breitman, T Saito, and A Ichikawa

The monocytic differentiation of HL60 induced by rat kidney NADPH- linked high-Km aldehyde reductase protein
J. Biol. Chem. 1989 264: 15624-15627. [Abstract] [PDF]  

GC Ferreira, RD Pratt, and PL Pedersen

Energy-linked anion transport. Cloning, sequencing, and characterization of a full length cDNA encoding the rat liver mitochondrial proton/phosphate symporter
J. Biol. Chem. 1989 264: 15628-15633. [Abstract] [PDF]  

JE Metherall, JL Goldstein, KL Luskey, and MS Brown

Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells
J. Biol. Chem. 1989 264: 15634-15641. [Abstract] [PDF]  

RH Kramer, KA McDonald, and MP Vu

Human melanoma cells express a novel integrin receptor for laminin [published erratum appears in J Biol Chem 1989 Dec 15;264(35):21432]
J. Biol. Chem. 1989 264: 15642-15649. [Abstract] [PDF]  

AC Carrera, L Cardenas, A Tugores, M Alonso, F Sanchez-Madrid, and MO de Landazuri

Activators of protein kinase C up-regulate the cell surface expression of CD2 and CD5 T cell glycoproteins
J. Biol. Chem. 1989 264: 15650-15655. [Abstract] [PDF]  

MR Wardell, CC Reynolds, MC Berndt, RW Wallace, and JE Fox

Platelet glycoprotein Ib beta is phosphorylated on serine 166 by cyclic AMP-dependent protein kinase
J. Biol. Chem. 1989 264: 15656-15661. [Abstract] [PDF]  

BG Grimwood, TH Plummer, Jr, and AL Tarentino

Carboxypeptidase H. A regulatory peptide-processing enzyme produced by human hepatoma Hep G2 cells
J. Biol. Chem. 1989 264: 15662-15667. [Abstract] [PDF]  

AE Traynor-Kaplan, BL Thompson, AL Harris, P Taylor, GM Omann, and LA Sklar

Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils
J. Biol. Chem. 1989 264: 15668-15673. [Abstract] [PDF]  

VL Giranda, HM Berman, and VL Schramm

Crystallographic quaternary structural analysis of AMP nucleosidases from Escherichia coli and Azotobacter vinelandii
J. Biol. Chem. 1989 264: 15674-15680. [Abstract] [PDF]  

K Usdin and AV Furano

The structure of the guanine-rich polypurine:polypyrimidine sequence at the right end of the rat L1 (LINE) element
J. Biol. Chem. 1989 264: 15681-15687. [Abstract] [PDF]  

M Kawata, A Kikuchi, M Hoshijima, K Yamamoto, E Hashimoto, H Yamamura, and Y Takai

Phosphorylation of smg p21, a ras p21-like GTP-binding protein, by cyclic AMP-dependent protein kinase in a cell-free system and in response to prostaglandin E1 in intact human platelets
J. Biol. Chem. 1989 264: 15688-15695. [Abstract] [PDF]  

RN Sifers, BB Rogers, HK Hawkins, MJ Finegold, and SL Woo

Elevated synthesis of human alpha 1-antitrypsin hinders the secretion of murine alpha 1-antitrypsin from hepatocytes of transgenic mice
J. Biol. Chem. 1989 264: 15696-15700. [Abstract] [PDF]  

K Bostrom, SJ Lauer, KS Poksay, Z Garcia, JM Taylor, and TL Innerarity

Apolipoprotein B48 RNA editing in chimeric apolipoprotein EB mRNA
J. Biol. Chem. 1989 264: 15701-15708. [Abstract] [PDF]  

JO Moskaug, K Sletten, K Sandvig, and S Olsnes

Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage
J. Biol. Chem. 1989 264: 15709-15713. [Abstract] [PDF]  

M Yanagishita, ML Brandi, and K Sakaguchi

Characterization of proteoglycans synthesized by a rat parathyroid cell line
J. Biol. Chem. 1989 264: 15714-15720. [Abstract] [PDF]  

EA Stura, RL Stanfield, TM Fieser, RS Balderas, LR Smith, RA Lerner, and IA Wilson

Preliminary crystallographic data and primary sequence for anti-peptide Fab' B13I2 and its complex with the C-helix peptide from myohemerythrin
J. Biol. Chem. 1989 264: 15721-15725. [Abstract] [PDF]  

J Ostrowski, JY Wu, DC Rueger, BE Miller, LM Siegel, and NM Kredich

Characterization of the cysJIH regions of Salmonella typhimurium and Escherichia coli B. DNA sequences of cysI and cysH and a model for the siroheme-Fe4S4 active center of sulfite reductase hemoprotein based on amino acid homology with spinach nitrite reductase
J. Biol. Chem. 1989 264: 15726-15737. [Abstract] [PDF]  

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