Minireviews

Joel Moss and Martha Vaughan

Molecules in the ARF Orbit
J. Biol. Chem. 1998 273: 21431-21434. [Full Text] [PDF]  

Communications

Maureen W. McEnery, Terry D. Copeland, and Courtney L. Vance

Altered Expression and Assembly of N-type Calcium Channel _1B and  Subunits in Epileptic lethargic (lh/lh) Mouse
J. Biol. Chem. 1998 273: 21435-21438. [Abstract] [Full Text] [PDF]  

Peter Milev, Hubert Monnerie, Susanna Popp, Renée K. Margolis, and Richard U. Margolis

The Core Protein of the Chondroitin Sulfate Proteoglycan Phosphacan Is a High-affinity Ligand of Fibroblast Growth Factor-2 and Potentiates Its Mitogenic Activity
J. Biol. Chem. 1998 273: 21439-21442. [Abstract] [Full Text] [PDF]  

Renuka C. Pillutla, Zhenyu Yue, Edio Maldonado, and Aaron J. Shatkin

Recombinant Human mRNA Cap Methyltransferase Binds Capping Enzyme/RNA Polymerase IIo Complexes
J. Biol. Chem. 1998 273: 21443-21446. [Abstract] [Full Text] [PDF]  

Kelly M. Trujillo, Shyng-Shiou F. Yuan, Eva Y.-H. P. Lee, and Patrick Sung

Nuclease Activities in a Complex of Human Recombination and DNA Repair Factors Rad50, Mre11, and p95
J. Biol. Chem. 1998 273: 21447-21450. [Abstract] [Full Text] [PDF]  

Mikhail Khvotchev and Thomas C. Südhof

Newly Synthesized Phosphatidylinositol Phosphates Are Required for Synaptic Norepinephrine but Not Glutamate or -Aminobutyric Acid (GABA) Release
J. Biol. Chem. 1998 273: 21451-21454. [Abstract] [Full Text] [PDF]  

Carbohydrates, Lipids, and Other Natural Products

Hideki Kamitani, Mark Geller, and Thomas Eling

Expression of 15-Lipoxygenase by Human Colorectal Carcinoma Caco-2 Cells during Apoptosis and Cell Differentiation
J. Biol. Chem. 1998 273: 21569-21577. [Abstract] [Full Text] [PDF]  

Tamar Megidish, Jonathan Cooper, Lixin Zhang, Haian Fu, and Sen-itiroh Hakomori

A Novel Sphingosine-dependent Protein Kinase (SDK1) Specifically Phosphorylates Certain Isoforms of 14-3-3 Protein
J. Biol. Chem. 1998 273: 21834-21845. [Abstract] [Full Text] [PDF]  

Janet W. Zimmerman, Johanna Lindermuth, Pamela A. Fish, Gerard P. Palace, Tom T. Stevenson, and Duane E. DeMong

A Novel Carbohydrate-Glycosphingolipid Interaction between a -(1-3)-Glucan Immunomodulator, PGG-glucan, and Lactosylceramide of Human Leukocytes
J. Biol. Chem. 1998 273: 22014-22020. [Abstract] [Full Text] [PDF]  

Cell Biology and Metabolism

Douglas K. Bishop, Uy Ear, Anamitra Bhattacharyya, Chris Calderone, Michael Beckett, Ralph R. Weichselbaum, and Akira Shinohara

Xrcc3 Is Required for Assembly of Rad51 Complexes in Vivo
J. Biol. Chem. 1998 273: 21482-21488. [Abstract] [Full Text] [PDF]  

Guillermo Velasco, Math J. H. Geelen, Teresa Gómez del Pulgar, and Manuel Guzmán

Malonyl-CoA-independent Acute Control of Hepatic Carnitine Palmitoyltransferase I Activity. ROLE OF Ca²⁺/CALMODULIN-DEPENDENT PROTEIN KINASE II AND CYTOSKELETAL COMPONENTS
J. Biol. Chem. 1998 273: 21497-21504. [Abstract] [Full Text] [PDF]  

Stuart R. Arden, Jeroo D. Sinor, William K. Potthoff, and Elias Aizenman

Subunit-specific Interactions of Cyanide with the N-Methyl-D-aspartate Receptor
J. Biol. Chem. 1998 273: 21505-21511. [Abstract] [Full Text] [PDF]  

Ulla G. Knaus, Yan Wang, Abina M. Reilly, Dawn Warnock, and Janis H. Jackson

Structural Requirements for PAK Activation by Rac GTPases
J. Biol. Chem. 1998 273: 21512-21518. [Abstract] [Full Text] [PDF]  

Tadashi Suzuki, Hangil Park, Ken Kitajima, and William J. Lennarz

Peptides Glycosylated in the Endoplasmic Reticulum of Yeast Are Subsequently Deglycosylated by a Soluble Peptide: N-Glycanase Activity
J. Biol. Chem. 1998 273: 21526-21530. [Abstract] [Full Text] [PDF]  

David G. Winkler, Richard E. Cutler Jr., Jonelle K. Drugan, Sharon Campbell, Deborah K. Morrison, and Jonathan A. Cooper

Identification of Residues in the Cysteine-rich Domain of Raf-1 That Control Ras Binding and Raf-1 Activity
J. Biol. Chem. 1998 273: 21578-21584. [Abstract] [Full Text] [PDF]  

Christian Hesslinger, Elisabeth Kremmer, Lothar Hültner, Marius Ueffing, and Irmgard Ziegler

Phosphorylation of GTP Cyclohydrolase I and Modulation of Its Activity in Rodent Mast Cells. GTP CYCLOHYDROLASE I HYPERPHOSPHORYLATION IS COUPLED TO HIGH AFFINITY IgE RECEPTOR SIGNALING AND INVOLVES PROTEIN KINASE C
J. Biol. Chem. 1998 273: 21616-21622. [Abstract] [Full Text] [PDF]  

Chandana Saha, Sanjay K. Nigam, and Bradley M. Denker

Involvement of G_i2 in the Maintenance and Biogenesis of Epithelial Cell Tight Junctions
J. Biol. Chem. 1998 273: 21629-21633. [Abstract] [Full Text] [PDF]  

Mustapha Najimi, Frédérique Souazé, Milagros Méndez, Emmanuel Hermans, Tsouria Berbar, William Rostène, and Patricia Forgez

Activation of Receptor Gene Transcription Is Required to Maintain Cell Sensitization after Agonist Exposure. STUDY ON NEUROTENSIN RECEPTOR
J. Biol. Chem. 1998 273: 21634-21641. [Abstract] [Full Text] [PDF]  

Katarzyna Rückemann, Lynette D. Fairbanks, Elizabeth A. Carrey, Catherine M. Hawrylowicz, David F. Richards, Bernhard Kirschbaum, and H. Anne Simmonds

Leflunomide Inhibits Pyrimidine de Novo Synthesis in Mitogen-stimulated T-lymphocytes from Healthy Humans
J. Biol. Chem. 1998 273: 21682-21691. [Abstract] [Full Text] [PDF]  

Tomas Drmota, Jiri Novotny, Gun-Do Kim, Karin A. Eidne, Graeme Milligan, and Petr Svoboda

Agonist-induced Internalization of the G Protein G₁₁ and Thyrotropin-releasing Hormone Receptors Proceed on Different Time Scales
J. Biol. Chem. 1998 273: 21699-21707. [Abstract] [Full Text] [PDF]  

Olga Kifor, Ruben Diaz, Robert Butters, Imre Kifor, and Edward M. Brown

The Calcium-sensing Receptor Is Localized in Caveolin-rich Plasma Membrane Domains of Bovine Parathyroid Cells
J. Biol. Chem. 1998 273: 21708-21713. [Abstract] [Full Text] [PDF]  

Peter D. Ho, Dietmar K. Zechner, Huaping He, Wolfgang H. Dillmann, Christopher C. Glembotski, and Patrick M. McDonough

The Raf-MEK-ERK Cascade Represents a Common Pathway for Alteration of Intracellular Calcium by Ras and Protein Kinase C in Cardiac Myocytes
J. Biol. Chem. 1998 273: 21730-21735. [Abstract] [Full Text] [PDF]  

Natalie D. DeWitt, Carlos F. Tourinho dos Santos, Kenneth E. Allen, and Carolyn W. Slayman

Phosphorylation Region of the Yeast Plasma-membrane H⁺-ATPase. ROLE IN PROTEIN FOLDING AND BIOGENESIS
J. Biol. Chem. 1998 273: 21744-21751. [Abstract] [Full Text] [PDF]  

Bryan D. Moyer, Johannes Loffing, Erik M. Schwiebert, Dominique Loffing-Cueni, Patricia A. Halpin, Katherine H. Karlson, Iskandar I. Ismailov, William B. Guggino, George M. Langford, and Bruce A. Stanton

Membrane Trafficking of the Cystic Fibrosis Gene Product, Cystic Fibrosis Transmembrane Conductance Regulator, Tagged with Green Fluorescent Protein in Madin-Darby Canine Kidney Cells
J. Biol. Chem. 1998 273: 21759-21768. [Abstract] [Full Text] [PDF]  

Helena Källström, Md. Shahidul Islam, Per-Olof Berggren, and Ann-Beth Jonsson

Cell Signaling by the Type IV Pili of Pathogenic Neisseria
J. Biol. Chem. 1998 273: 21777-21782. [Abstract] [Full Text] [PDF]  

Yue Xu, Siew Heng Wong, Bor Luen Tang, V. Nathan Subramaniam, Tao Zhang, and Wanjin Hong

A 29-Kilodalton Golgi Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (Vti1-rp2) Implicated in Protein Trafficking in the Secretory Pathway
J. Biol. Chem. 1998 273: 21783-21789. [Abstract] [Full Text] [PDF]  

Luc Vanhamme, David Perez-Morga, Christian Marchal, Dave Speijer, Laurence Lambert, Maurice Geuskens, Sylvie Alexandre, Naïma Ismaïli, Ulrich Göringer, Rob Benne, and Etienne Pays

Trypanosoma brucei TBRGG1, a Mitochondrial Oligo(U)-binding Protein That Co-localizes with an in Vitro RNA Editing Activity
J. Biol. Chem. 1998 273: 21825-21833. [Abstract] [Full Text] [PDF]  

Markus Essler, Mutsuki Amano, Hans-Joachim Kruse, Kozo Kaibuchi, Peter C. Weber, and Martin Aepfelbacher

Thrombin Inactivates Myosin Light Chain Phosphatase via Rho and Its Target Rho Kinase in Human Endothelial Cells
J. Biol. Chem. 1998 273: 21867-21874. [Abstract] [Full Text] [PDF]  

Kotha Subbaramaiah, Wen Jing Chung, Pedro Michaluart, Nitin Telang, Tadashi Tanabe, Hiroyasu Inoue, Meishiang Jang, John M. Pezzuto, and Andrew J. Dannenberg

Resveratrol Inhibits Cyclooxygenase-2 Transcription and Activity in Phorbol Ester-treated Human Mammary Epithelial Cells
J. Biol. Chem. 1998 273: 21875-21882. [Abstract] [Full Text] [PDF]  

Trond Olav Berg, Monica Fengsrud, Per Eivind Strømhaug, Trond Berg, and Per O. Seglen

Isolation and Characterization of Rat Liver Amphisomes. EVIDENCE FOR FUSION OF AUTOPHAGOSOMES WITH BOTH EARLY AND LATE ENDOSOMES
J. Biol. Chem. 1998 273: 21883-21892. [Abstract] [Full Text] [PDF]  

Leena Heiska, Kaija Alfthan, Mikaela Grönholm, Pekka Vilja, Antti Vaheri, and Olli Carpén

Association of Ezrin with Intercellular Adhesion Molecule-1 and -2 (ICAM-1 and ICAM-2). REGULATION BY PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE
J. Biol. Chem. 1998 273: 21893-21900. [Abstract] [Full Text] [PDF]  

Hong Liao, Yarong Li, David L. Brautigan, and Gregg G. Gundersen

Protein Phosphatase 1 Is Targeted to Microtubules by the Microtubule-associated Protein Tau
J. Biol. Chem. 1998 273: 21901-21908. [Abstract] [Full Text] [PDF]  

Kathryn W. Underwood, Chuanzheng Song, Ronald W. Kriz, Xiao Jia Chang, John L. Knopf, and Lih-Ling Lin

A Novel Calcium-independent Phospholipase A₂, cPLA₂-, That Is Prenylated and Contains Homology to cPLA₂
J. Biol. Chem. 1998 273: 21926-21932. [Abstract] [Full Text] [PDF]  

Andrew B. Maksymowych and Lance L. Simpson

Binding and Transcytosis of Botulinum Neurotoxin by Polarized Human Colon Carcinoma Cells
J. Biol. Chem. 1998 273: 21950-21957. [Abstract] [Full Text] [PDF]  

Hiroshi Yasuda, Margaret A. Lindorfer, Chang-Seon Myung, and James C. Garrison

Phosphorylation of the G Protein ₁₂ Subunit Regulates Effector Specificity
J. Biol. Chem. 1998 273: 21958-21965. [Abstract] [Full Text] [PDF]  

Stephen H. Gee, Stacy A. Sekely, Christian Lombardo, Alexei Kurakin, Stanley C. Froehner, and Brian K. Kay

Cyclic Peptides as Non-carboxyl-terminal Ligands of Syntrophin PDZ Domains
J. Biol. Chem. 1998 273: 21980-21987. [Abstract] [Full Text] [PDF]  

Christian Callebaut, Julià Blanco, Nadia Benkirane, Bernard Krust, Etienne Jacotot, Gilles Guichard, Nabila Seddiki, Josette Svab, Elisabeth Dam, Sylviane Muller, Jean-Paul Briand, and Ara G. Hovanessian

Identification of V3 Loop-binding Proteins as Potential Receptors Implicated in the Binding of HIV Particles to CD4⁺ Cells
J. Biol. Chem. 1998 273: 21988-21997. [Abstract] [Full Text] [PDF]  

Jean-Olivier Contreres, Robert Faure, Gerardo Baquiran, John J. Bergeron, and Barry I. Posner

ATP-dependent Desensitization of Insulin Binding and Tyrosine Kinase Activity of the Insulin Receptor Kinase. THE ROLE OF ENDOSOMAL ACIDIFICATION
J. Biol. Chem. 1998 273: 22007-22013. [Abstract] [Full Text] [PDF]  

Tatsuya Moriyama, Susan K. Sather, Todd P. McGee, and Robert D. Simoni

Degradation of HMG-CoA Reductase in Vitro. CLEAVAGE IN THE MEMBRANE DOMAIN BY A MEMBRANE-BOUND CYSTEINE PROTEASE
J. Biol. Chem. 1998 273: 22037-22043. [Abstract] [Full Text] [PDF]  

Emmanuel Morelon and Alice Dautry-Varsat

Endocytosis of the Common Cytokine Receptor _c Chain. IDENTIFICATION OF SEQUENCES INVOLVED IN INTERNALIZATION AND DEGRADATION
J. Biol. Chem. 1998 273: 22044-22051. [Abstract] [Full Text] [PDF]  

Cindy N. Gross, Alivelu Irrinki, John N. Feder, and Caroline A. Enns

Co-trafficking of HFE, a Nonclassical Major Histocompatibility Complex Class I Protein, with the Transferrin Receptor Implies a Role in Intracellular Iron Regulation
J. Biol. Chem. 1998 273: 22068-22074. [Abstract] [Full Text] [PDF]  

Tzu-Ching Meng and Ming-Fong Lin

Tyrosine Phosphorylation of c-ErbB-2 Is Regulated by the Cellular Form of Prostatic Acid Phosphatase in Human Prostate Cancer Cells
J. Biol. Chem. 1998 273: 22096-22104. [Abstract] [Full Text] [PDF]  

Menq-Jer Lee, Shobha Thangada, Catherine H. Liu, Brian D. Thompson, and Timothy Hla

Lysophosphatidic Acid Stimulates the G-protein-coupled Receptor EDG-1 as a Low Affinity Agonist
J. Biol. Chem. 1998 273: 22105-22112. [Abstract] [Full Text] [PDF]  

David W. Griggs, Christina M. Schmidt, and Christopher P. Carron

Characteristics of Cation Binding to the I Domains of LFA-1 and MAC-1. THE LFA-1 I DOMAIN CONTAINS A Ca²⁺-BINDING SITE
J. Biol. Chem. 1998 273: 22113-22119. [Abstract] [Full Text] [PDF]  

Enrico Giraudo, Luca Primo, Enrica Audero, Hans-Peter Gerber, Pieter Koolwijk, Shay Soker, Michael Klagsbrun, Napoleone Ferrara, and Federico Bussolino

Tumor Necrosis Factor- Regulates Expression of Vascular Endothelial Growth Factor Receptor-2 and of Its Co-receptor Neuropilin-1 in Human Vascular Endothelial Cells
J. Biol. Chem. 1998 273: 22128-22135. [Abstract] [Full Text] [PDF]  

Olivier Guittet, Béatrice Ducastel, Jerome S. Salem, Yann Henry, Harvey Rubin, Geneviève Lemaire, and Michel Lepoivre

Differential Sensitivity of the Tyrosyl Radical of Mouse Ribonucleotide Reductase to Nitric Oxide and Peroxynitrite
J. Biol. Chem. 1998 273: 22136-22144. [Abstract] [Full Text] [PDF]  

Marta Bosch, Joan Gil, Oriol Bachs, and Neus Agell

Calmodulin Inhibitor W13 Induces Sustained Activation of ERK2 and Expression of p21^cip1
J. Biol. Chem. 1998 273: 22145-22150. [Abstract] [Full Text] [PDF]  

David A. Scott, Wanderley de Souza, Marlene Benchimol, Li Zhong, Hong-Gang Lu, Silvia N. J. Moreno, and Roberto Docampo

Presence of a Plant-like Proton-pumping Pyrophosphatase in Acidocalcisomes of Trypanosoma cruzi
J. Biol. Chem. 1998 273: 22151-22158. [Abstract] [Full Text] [PDF]  

Enzymology

Peter Paul Schmidt, Ulrika Rova, Bettina Katterle, Lars Thelander, and Astrid Gräslund

Kinetic Evidence That a Radical Transfer Pathway in Protein R2 of Mouse Ribonucleotide Reductase Is Involved in Generation of the Tyrosyl Free Radical
J. Biol. Chem. 1998 273: 21463-21472. [Abstract] [Full Text] [PDF]  

Shogo Ikeda, Tapan Biswas, Rabindra Roy, Tadahide Izumi, Istvan Boldogh, Alexander Kurosky, Altaf H. Sarker, Shuji Seki, and Sankar Mitra

Purification and Characterization of Human NTH1, a Homolog of Escherichia coli Endonuclease III. DIRECT IDENTIFICATION OF LYS-212 AS THE ACTIVE NUCLEOPHILIC RESIDUE
J. Biol. Chem. 1998 273: 21585-21593. [Abstract] [Full Text] [PDF]  

Annerose Schneider, Richard W. P. Smith, Armin R. Kautz, Klaus Weisshart, Frank Grosse, and Heinz-Peter Nasheuer

Primase Activity of Human DNA Polymerase -Primase. DIVALENT CATIONS STABILIZE THE ENZYME ACTIVITY OF THE p48 SUBUNIT
J. Biol. Chem. 1998 273: 21608-21615. [Abstract] [Full Text] [PDF]  

Marianne Ridderström, Alexander D. Cameron, T. Alwyn Jones, and Bengt Mannervik

Involvement of an Active-site Zn²⁺ Ligand in the Catalytic Mechanism of Human Glyoxalase I
J. Biol. Chem. 1998 273: 21623-21628. [Abstract] [Full Text] [PDF]  

Françoise Haeseleer, Jing Huang, Lukasz Lebioda, John C. Saari, and Krzysztof Palczewski

Molecular Characterization of a Novel Short-chain Dehydrogenase/Reductase That Reduces All-trans-retinal
J. Biol. Chem. 1998 273: 21790-21799. [Abstract] [Full Text] [PDF]  

Yudong Quan, Phil Inouye, Chen Liang, Liwei Rong, Matthias Götte, and Mark A. Wainberg

Dominance of the E89G Substitution in HIV-1 Reverse Transcriptase in Regard to Increased Polymerase Processivity and Patterns of Pausing
J. Biol. Chem. 1998 273: 21918-21925. [Abstract] [Full Text] [PDF]  

Pavel Kramata, Kathleen M. Downey, and Lisa R. Paborsky

Incorporation and Excision of 9-(2-Phosphonylmethoxyethyl)guanine (PMEG) by DNA Polymerase  and  in Vitro
J. Biol. Chem. 1998 273: 21966-21971. [Abstract] [Full Text] [PDF]  

Roy Roberts, Vicki A. Sciorra, and Andrew J. Morris

Human Type 2 Phosphatidic Acid Phosphohydrolases. SUBSTRATE SPECIFICITY OF THE TYPE 2a, 2b, AND 2c ENZYMES AND CELL SURFACE ACTIVITY OF THE 2a ISOFORM
J. Biol. Chem. 1998 273: 22059-22067. [Abstract] [Full Text] [PDF]  

Grant W. Brown and Thomas J. Kelly

Purification of Hsk1, a Minichromosome Maintenance Protein Kinase from Fission Yeast
J. Biol. Chem. 1998 273: 22083-22090. [Abstract] [Full Text] [PDF]  

Membranes and Bioenergetics

Tomohiko Sato, Hiroki Konno, Yasufumi Tanaka, Takao Kataoka, Kazuo Nagai, Harry H. Wasserman, and Shoji Ohkuma

Prodigiosins as a New Group of H⁺/Cl Symporters That Uncouple Proton Translocators
J. Biol. Chem. 1998 273: 21455-21462. [Abstract] [Full Text] [PDF]  

Manickavasagam Sundaram, Sylvia Y. M. Yao, Amy M. L. Ng, Mark Griffiths, Carol E. Cass, Stephen A. Baldwin, and James D. Young

Chimeric Constructs between Human and Rat Equilibrative Nucleoside Transporters (hENT1 and rENT1) Reveal hENT1 Structural Domains Interacting with Coronary Vasoactive Drugs
J. Biol. Chem. 1998 273: 21519-21525. [Abstract] [Full Text] [PDF]  

David H. Vandorpe, Boris E. Shmukler, Lianwei Jiang, Bing Lim, James Maylie, John P. Adelman, Lucia de Franceschi, M. Domenica Cappellini, Carlo Brugnara, and Seth L. Alper

cDNA Cloning and Functional Characterization of the Mouse Ca²⁺-gated K⁺ Channel, mIK1. ROLES IN REGULATORY VOLUME DECREASE AND ERYTHROID DIFFERENTIATION
J. Biol. Chem. 1998 273: 21542-21553. [Abstract] [Full Text] [PDF]  

Susanne Jünemann, Peter Heathcote, and Peter R. Rich

On the Mechanism of Quinol Oxidation in the bc₁ Complex
J. Biol. Chem. 1998 273: 21603-21607. [Abstract] [Full Text] [PDF]  

Jerry Eichler, Kate Rinard, and William Wickner

Endogenous SecA Catalyzes Preprotein Translocation at SecYEG
J. Biol. Chem. 1998 273: 21675-21681. [Abstract] [Full Text] [PDF]  

Taeho Ahn and Hyoungman Kim

Effects of Nonlamellar-prone Lipids on the ATPase Activity of SecA Bound to Model Membranes
J. Biol. Chem. 1998 273: 21692-21698. [Abstract] [Full Text] [PDF]  

Mamoru Yamada, Hisayo Inbe, Makoto Tanaka, Kenichi Sumi, Kazunobu Matsushita, and Osao Adachi

Mutant Isolation of the Escherichia coli Quinoprotein Glucose Dehydrogenase and Analysis of Crucial Residues Asp-730 and His-775 for Its Function
J. Biol. Chem. 1998 273: 22021-22027. [Abstract] [Full Text] [PDF]  

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Dindial Ramotar, Edith Belanger, Isabelle Brodeur, Jean-Yves Masson, and Elliot A. Drobetsky

A Yeast Homologue of the Human Phosphotyrosyl Phosphatase Activator PTPA Is Implicated in Protection against Oxidative DNA Damage Induced by the Model Carcinogen 4-Nitroquinoline 1-Oxide
J. Biol. Chem. 1998 273: 21489-21496. [Abstract] [Full Text] [PDF]  

Sanjaya Singh, Hank Kejun Tang, Jing-Yu Lee, and Grady F. Saunders

Truncation Mutations in the Transactivation Region of PAX6 Result in Dominant-Negative Mutants
J. Biol. Chem. 1998 273: 21531-21541. [Abstract] [Full Text] [PDF]  

Akira Takeshita, Paul M. Yen, Masato Ikeda, Guemalli R. Cardona, Ying Liu, Noriyuki Koibuchi, Errol R. Norwitz, and William W. Chin

Thyroid Hormone Response Elements Differentially Modulate the Interactions of Thyroid Hormone Receptors with Two Receptor Binding Domains in the Steroid Receptor Coactivator-1
J. Biol. Chem. 1998 273: 21554-21562. [Abstract] [Full Text] [PDF]  

Andre L. Reed, Hitoshi Yamazaki, Joshua D. Kaufman, Yaffa Rubinstein, Barbara Murphy, and Alfred C. Johnson

Molecular Cloning and Characterization of a Transcription Regulator with Homology to GC-binding Factor
J. Biol. Chem. 1998 273: 21594-21602. [Abstract] [Full Text] [PDF]  

Koshichi Gotoh, Hiroshi Yokota, Eriko Kikuya, Toshio Watanabe, and Michio Oishi

Genomic Structure of MUNC18-1 Protein, Which Is Involved in Docking and Fusion of Synaptic Vesicles in Brain
J. Biol. Chem. 1998 273: 21642-21647. [Abstract] [Full Text] [PDF]  

Upinder Singh and Joshua B. Rogers

The Novel Core Promoter Element GAAC in the hgl5 Gene of Entamoeba histolytica Is Able to Direct a Transcription Start Site Independent of TATA or Initiator Regions
J. Biol. Chem. 1998 273: 21663-21668. [Abstract] [Full Text] [PDF]  

Iqbal Hamza, Sarita Chauhan, Richard Hassett, and Mark R. O'Brian

The Bacterial Irr Protein Is Required for Coordination of Heme Biosynthesis with Iron Availability
J. Biol. Chem. 1998 273: 21669-21674. [Abstract] [Full Text] [PDF]  

Nancy C. Horton and John J. Perona

Recognition of Flanking DNA Sequences by EcoRV Endonuclease Involves Alternative Patterns of Water-mediated Contacts
J. Biol. Chem. 1998 273: 21721-21729. [Abstract] [Full Text] [PDF]  

Lars B. Nielsen, Debra Kahn, Thomas Duell, Heinz-Ulrich G. Weier, Stacy Taylor, and Stephen G. Young

Apolipoprotein B Gene Expression in a Series of Human Apolipoprotein B Transgenic Mice Generated with recA-assisted Restriction Endonuclease Cleavage-modified Bacterial Artificial Chromosomes. AN INTESTINE-SPECIFIC ENHANCER ELEMENT IS LOCATED BETWEEN 54 AND 62 KILOBASES 5' TO THE STRUCTURAL GENE
J. Biol. Chem. 1998 273: 21800-21807. [Abstract] [Full Text] [PDF]  

Malcolm Collins, Ponlapat Rojnuckarin, Yu-Hong Zhu, and Paul Bornstein

A Far Upstream, Cell Type-specific Enhancer of the Mouse Thrombospondin 3 Gene Is Located within Intron 6 of the Adjacent Metaxin Gene
J. Biol. Chem. 1998 273: 21816-21824. [Abstract] [Full Text] [PDF]  

David L. Fouts, Gabrielle A. Stryker, Kevin S. Gorski, Mark J. Miller, Thanh V. Nguyen, Ruth A. Wrightsman, and Jerry E. Manning

Evidence for Four Distinct Major Protein Components in the Paraflagellar Rod of Trypanosoma cruzi
J. Biol. Chem. 1998 273: 21846-21855. [Abstract] [Full Text] [PDF]  

Chung S. Song, Myeong H. Jung, Sang C. Kim, Tina Hassan, Arun K. Roy, and Bandana Chatterjee

Tissue-specific and Androgen-repressible Regulation of the Rat Dehydroepiandrosterone Sulfotransferase Gene Promoter
J. Biol. Chem. 1998 273: 21856-21866. [Abstract] [Full Text] [PDF]  

Colin A. Smith, Jared Baeten, and John-Stephen Taylor

The Ability of a Variety of Polymerases to Synthesize Past Site-specific cis-syn, trans-syn-II, (6-4), and Dewar Photoproducts of Thymidylyl-(3'5')-thymidine
J. Biol. Chem. 1998 273: 21933-21940. [Abstract] [Full Text] [PDF]  

Hiroshi Ishiguro, Kouji Yamada, Naohiro Ichino, and Toshiharu Nagatsu

Identification and Characterization of a Novel Phorbol Ester-responsive DNA Sequence in the 5'-Flanking Region of the Human Dopamine -Hydroxylase Gene
J. Biol. Chem. 1998 273: 21941-21949. [Abstract] [Full Text] [PDF]  

Neil K. Brewster, Gerald C. Johnston, and Richard A. Singer

Characterization of the CP Complex, an Abundant Dimer of Cdc68 and Pob3 Proteins That Regulates Yeast Transcriptional Activation and Chromatin Repression
J. Biol. Chem. 1998 273: 21972-21979. [Abstract] [Full Text] [PDF]  

Evelyne Myslinski, Alain Krol, and Philippe Carbon

ZNF76 and ZNF143 Are Two Human Homologs of the Transcriptional Activator Staf
J. Biol. Chem. 1998 273: 21998-22006. [Abstract] [Full Text] [PDF]  

Birgitta Ruth Knudsen, Jehee Lee, Michael Lisby, Ole Westergaard, and Makkuni Jayaram

Alcoholysis and Strand Joining by the Flp Site-specific Recombinase. MECHANISTICALLY EQUIVALENT REACTIONS MEDIATED BY DISTINCT CATALYTIC CONFIGURATIONS
J. Biol. Chem. 1998 273: 22028-22036. [Abstract] [Full Text] [PDF]  

David E. Tabor, Jae B. Kim, Bruce M. Spiegelman, and Peter A. Edwards

Transcriptional Activation of the Stearoyl-CoA Desaturase 2 Gene by Sterol Regulatory Element-binding Protein/Adipocyte Determination and Differentiation Factor 1
J. Biol. Chem. 1998 273: 22052-22058. [Abstract] [Full Text] [PDF]  

Wade A. Bresnahan, Thomas Albrecht, and E. Aubrey Thompson

The Cyclin E Promoter Is Activated by Human Cytomegalovirus 86-kDa Immediate Early Protein
J. Biol. Chem. 1998 273: 22075-22082. [Abstract] [Full Text] [PDF]  

Hongmiao Sheng, Christopher S. Williams, Jinyi Shao, Peng Liang, Raymond N. DuBois, and R. Daniel Beauchamp

Induction of Cyclooxygenase-2 by Activated Ha-ras Oncogene in Rat-1 Fibroblasts and the Role of Mitogen-activated Protein Kinase Pathway
J. Biol. Chem. 1998 273: 22120-22127. [Abstract] [Full Text] [PDF]  

Protein Chemistry and Structure

Masayuki Matsushita and Angus C. Nairn

Characterization of the Mechanism of Regulation of Ca²⁺/ Calmodulin-dependent Protein Kinase I by Calmodulin and by Ca²⁺/Calmodulin-dependent Protein Kinase Kinase
J. Biol. Chem. 1998 273: 21473-21481. [Abstract] [Full Text] [PDF]  

Tracy A. Spalding, Ethan S. Burstein, Shaw C. Henderson, Karin R. Ducote, and Mark R. Brann

Identification of a Ligand-dependent Switch within a Muscarinic Receptor
J. Biol. Chem. 1998 273: 21563-21568. [Abstract] [Full Text] [PDF]  

Jan Potempa, Jowita Mikolajczyk-Pawlinska, David Brassell, Daniel Nelson, Ida B. Thøgersen, Jan J. Enghild, and James Travis

Comparative Properties of Two Cysteine Proteinases (Gingipains R), the Products of Two Related but Individual Genes of Porphyromonas gingivalis
J. Biol. Chem. 1998 273: 21648-21657. [Abstract] [Full Text] [PDF]  

Chi-Jiunn Pan, Ke-Jian Lei, and Janice Yang Chou

Asparagine-linked Oligosaccharides Are Localized to a Luminal Hydrophilic Loop in Human Glucose-6-Phosphatase
J. Biol. Chem. 1998 273: 21658-21662. [Abstract] [Full Text] [PDF]  

Marie Zhang, Cynthia V. Stauffacher, Dayin Lin, and Robert L. Van Etten

Crystal Structure of a Human Low Molecular Weight Phosphotyrosyl Phosphatase. IMPLICATIONS FOR SUBSTRATE SPECIFICITY
J. Biol. Chem. 1998 273: 21714-21720. [Abstract] [Full Text] [PDF]  

Frederick W. Muskett, Tom A. Frenkiel, James Feeney, Robert B. Freedman, Mark D. Carr, and Richard A. Williamson

High Resolution Structure of the N-terminal Domain of Tissue Inhibitor of Metalloproteinases-2 and Characterization of Its Interaction Site with Matrix Metalloproteinase-3
J. Biol. Chem. 1998 273: 21736-21743. [Abstract] [Full Text] [PDF]  

Bruce A. Posner, Mark B. Mixon, Mark A. Wall, Stephen R. Sprang, and Alfred G. Gilman

The A326S Mutant of G_i1 as an Approximation of the Receptor-bound State
J. Biol. Chem. 1998 273: 21752-21758. [Abstract] [Full Text] [PDF]  

Alessandro Pini, Francesca Viti, Annalisa Santucci, Barbara Carnemolla, Luciano Zardi, Paolo Neri, and Dario Neri

Design and Use of a Phage Display Library. HUMAN ANTIBODIES WITH SUBNANOMOLAR AFFINITY AGAINST A MARKER OF ANGIOGENESIS ELUTED FROM A TWO-DIMENSIONAL GEL
J. Biol. Chem. 1998 273: 21769-21776. [Abstract] [Full Text] [PDF]  

Michael Natochin, Alexey E. Granovsky, and Nikolai O. Artemyev

Identification of Effector Residues on Photoreceptor G Protein, Transducin
J. Biol. Chem. 1998 273: 21808-21815. [Abstract] [Full Text] [PDF]  

Susan Muller-Weeks, Beverly Mastran, and Sal Caradonna

The Nuclear Isoform of the Highly Conserved Human Uracil-DNA Glycosylase Is an M_r 36,000 Phosphoprotein
J. Biol. Chem. 1998 273: 21909-21917. [Abstract] [Full Text] [PDF]  

Chris Illidge, Cay Kielty, and Adrian Shuttleworth

The 1(VIII) and 2(VIII) Chains of Type VIII Collagen Can Form Stable Homotrimeric Molecules
J. Biol. Chem. 1998 273: 22091-22095. [Abstract] [Full Text] [PDF]  

Additions and Corrections

Steven B. Vik, Annette Rochelle Patterson, and Barbara J. Antonio

Additions and Corrections to Insertion scanning mutagenesis of subunit a of the F₁F₀ ATP synthase near His²⁴⁵ and implications on gating of the proton channel.
J. Biol. Chem. 1998 273: 22159. [Full Text] [PDF]  

Kenta Hara, Kazuyoshi Yonezawa, Qing-Ping Weng, Mark T. Kozlowski, Christopher Belham, and Joseph Avruch

Additions and Corrections to Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism.
J. Biol. Chem. 1998 273: 22160. [Full Text] [PDF]  

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