Minireviews

Hydar Ali, Ricardo M. Richardson, Bodduluri Haribabu, and Ralph Snyderman

Chemoattractant Receptor Cross-desensitization
1999 274: 6027-6030. [Full Text] [PDF]

Communications

Martin Moche, Gunter Schneider, Patricia Edwards, Katayoon Dehesh, and Ylva Lindqvist

Structure of the Complex between the Antibiotic Cerulenin and Its Target, -Ketoacyl-Acyl Carrier Protein Synthase
1999 274: 6031-6034. [Abstract] [Full Text] [PDF]

Masakazu Yamazaki, Yue Zhang, Hiroshi Watanabe, Takeaki Yokozeki, Sigeo Ohno, Kozo Kaibuchi, Hideki Shibata, Hideyuki Mukai, Yoshitaka Ono, Michael A. Frohman, and Yasunori Kanaho

Interaction of the Small G Protein RhoA with the C Terminus of Human Phospholipase D1
1999 274: 6035-6038. [Abstract] [Full Text] [PDF]

Ren-Wu Chen and De-Maw Chuang

Long Term Lithium Treatment Suppresses p53 and Bax Expression but Increases Bcl-2 Expression. A PROMINENT ROLE IN NEUROPROTECTION AGAINST EXCITOTOXICITY
1999 274: 6039-6042. [Abstract] [Full Text] [PDF]

Tatsuya Sueyoshi, Takeshi Kawamoto, Igor Zelko, Paavo Honkakoski, and Masahiko Negishi

The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene
1999 274: 6043-6046. [Abstract] [Full Text] [PDF]

R. Hugh Daniels, Frank T. Zenke, and Gary M. Bokoch

Pix Stimulates p21-activated Kinase Activity through Exchange Factor-dependent and -independent Mechanisms
1999 274: 6047-6050. [Abstract] [Full Text] [PDF]

Carbohydrates, Lipids, and Other Natural Products

Ye Zhang and Yuan C. Lee

Acid-catalyzed Lactonization of 2,8-Linked Oligo/Polysialic Acids Studied by High Performance Anion-exchange Chromatography
1999 274: 6183-6189. [Abstract] [Full Text] [PDF]

Joern Jungmann, Julian C. Rayner, and Sean Munro

The Saccharomyces cerevisiae Protein Mnn10p/Bed1p Is a Subunit of a Golgi Mannosyltransferase Complex
1999 274: 6579-6585. [Abstract] [Full Text] [PDF]

Jonathan M. Moss, Gavin E. Reid, Kylie A. Mullin, Jody L. Zawadzki, Richard J. Simpson, and Malcolm J. McConville

Characterization of a Novel GDP-mannose:Serine-protein Mannose-1-phosphotransferase from Leishmania mexicana
1999 274: 6678-6688. [Abstract] [Full Text] [PDF]

Cell Biology and Metabolism

Benny Hung-Junn Chang, Wei Liao, Lan Li, Makoto Nakamuta, David Mack, and Lawrence Chan

Liver-specific Inactivation of the Abetalipoproteinemia Gene Completely Abrogates Very Low Density Lipoprotein/Low Density Lipoprotein Production in a Viable Conditional Knockout Mouse
1999 274: 6051-6055. [Abstract] [Full Text] [PDF]

Byungsuk Kwon, Kang-Yeol Yu, Jian Ni, Guo-Liang Yu, Ihn-Kyung Jang, Young-June Kim, Lily Xing, Ding Liu, Shu-Xia Wang, and Byoung S. Kwon

Identification of a Novel Activation-inducible Protein of the Tumor Necrosis Factor Receptor Superfamily and Its Ligand
1999 274: 6056-6061. [Abstract] [Full Text] [PDF]

Susan L. Cranmer, Philippe Ulsemer, Brian M. Cooke, Hatem H. Salem, Corinne de la Salle, Francois Lanza, and Shaun P. Jackson

Glycoprotein (GP) Ib-IX-transfected Cells Roll on a von Willebrand Factor Matrix under Flow. IMPORTANCE OF THE GPIb/ACTIN-BINDING PROTEIN (ABP-280) INTERACTION IN MAINTAINING ADHESION UNDER HIGH SHEAR
1999 274: 6097-6106. [Abstract] [Full Text] [PDF]

Cristina Purcarea, David R. Evans, and Guy Hervé

Channeling of Carbamoyl Phosphate to the Pyrimidine and Arginine Biosynthetic Pathways in the Deep Sea Hyperthermophilic Archaeon Pyrococcus abyssi
1999 274: 6122-6129. [Abstract] [Full Text] [PDF]

Christoph V. Suschek, Verena Krischel, Daniela Bruch-Gerharz, Denise Berendji, Jean Krutmann, Klaus-Dietrich Kröncke, and Victoria Kolb-Bachofen

Nitric Oxide Fully Protects against UVA-induced Apoptosis in Tight Correlation with Bcl-2 Up-regulation
1999 274: 6130-6137. [Abstract] [Full Text] [PDF]

Nicholas S. Tolwinski, Paul S. Shapiro, Said Goueli, and Natalie G. Ahn

Nuclear Localization of Mitogen-activated Protein Kinase Kinase 1 (MKK1) Is Promoted by Serum Stimulation and G2-M Progression. REQUIREMENT FOR PHOSPHORYLATION AT THE ACTIVATION LIP AND SIGNALING DOWNSTREAM OF MKK
1999 274: 6168-6174. [Abstract] [Full Text] [PDF]

Diane E. McCloskey, Catherine S. Coleman, and Anthony E. Pegg

Properties and Regulation of Human Spermidine/Spermine N¹-Acetyltransferase Stably Expressed in Chinese Hamster Ovary Cells
1999 274: 6175-6182. [Abstract] [Full Text] [PDF]

Katrina Mackay and Daria Mochly-Rosen

An Inhibitor of p38 Mitogen-activated Protein Kinase Protects Neonatal Cardiac Myocytes from Ischemia
1999 274: 6272-6279. [Abstract] [Full Text] [PDF]

Vincenzo Di Bartolo, Dominique Mège, Valérie Germain, Michele Pelosi, Evelyne Dufour, Frédérique Michel, Giovanni Magistrelli, Antonella Isacchi, and Oreste Acuto

Tyrosine 319, a Newly Identified Phosphorylation Site of ZAP-70, Plays a Critical Role in T Cell Antigen Receptor Signaling
1999 274: 6285-6294. [Abstract] [Full Text] [PDF]

Colleen M. Brophy, Mary Dickinson, and David Woodrum

Phosphorylation of the Small Heat Shock-related Protein, HSP20, in Vascular Smooth Muscles Is Associated with Changes in the Macromolecular Associations of HSP20
1999 274: 6324-6329. [Abstract] [Full Text] [PDF]

Chang-Bai Liu, Tohru Itoh, Ken-ichi Arai, and Sumiko Watanabe

Constitutive Activation of JAK2 Confers Murine Interleukin-3-independent Survival and Proliferation of BA/F3 Cells
1999 274: 6342-6349. [Abstract] [Full Text] [PDF]

Craig A. Aspinwall, Jonathan R. T. Lakey, and Robert T. Kennedy

Insulin-stimulated Insulin Secretion in Single Pancreatic Beta Cells
1999 274: 6360-6365. [Abstract] [Full Text] [PDF]

Kentaro Ozawa, Keisuke Kuwabara, Michio Tamatani, Kohichi Takatsuji, Yoshitane Tsukamoto, Sumiko Kaneda, Hideki Yanagi, David M. Stern, Yutaka Eguchi, Yoshihide Tsujimoto, Satoshi Ogawa, and Masaya Tohyama

150-kDa Oxygen-regulated Protein (ORP150) Suppresses Hypoxia-induced Apoptotic Cell Death
1999 274: 6397-6404. [Abstract] [Full Text] [PDF]

Barbara A. Froesch, Christine Aimé-Sempé, Brian Leber, David Andrews, and John C. Reed

Inhibition of p53 Transcriptional Activity by Bcl-2 Requires Its Membrane-anchoring Domain
1999 274: 6469-6475. [Abstract] [Full Text] [PDF]

Pranab K. Mukherjee, Mark A. DeCoster, Foster Z. Campbell, Roger J. Davis, and Nicolas G. Bazan

Glutamate Receptor Signaling Interplay Modulates Stress-sensitive Mitogen-activated Protein Kinases and Neuronal Cell Death
1999 274: 6493-6498. [Abstract] [Full Text] [PDF]

Robbert van der Voort, Taher E. I. Taher, Vera J. M. Wielenga, Marcel Spaargaren, Remko Prevo, Lia Smit, Guido David, Guido Hartmann, Ermanno Gherardi, and Steven T. Pals

Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-Met
1999 274: 6499-6506. [Abstract] [Full Text] [PDF]

Pekka J. Kallio, William J. Wilson, Sallyann O'Brien, Yuichi Makino, and Lorenz Poellinger

Regulation of the Hypoxia-inducible Transcription Factor 1 by the Ubiquitin-Proteasome Pathway
1999 274: 6519-6525. [Abstract] [Full Text] [PDF]

Françoise Haeseleer, Izabela Sokal, Ning Li, Mark Pettenati, Nagesh Rao, Darin Bronson, Rita Wechter, Wolfgang Baehr, and Krzysztof Palczewski

Molecular Characterization of a Third Member of the Guanylyl Cyclase-activating Protein Subfamily
1999 274: 6526-6535. [Abstract] [Full Text] [PDF]

Agnès Viale, Christine Ortola, Guillaume Hervieu, Machi Furuta, Pierre Barbero, Donald F. Steiner, Nabil G. Seidah, and Jean-Louis Nahon

Cellular Localization and Role of Prohormone Convertases in the Processing of Pro-melanin Concentrating Hormone in Mammals
1999 274: 6536-6545. [Abstract] [Full Text] [PDF]

Mangeng Cheng, Demin Wang, and Martine F. Roussel

Expression of c-Myc in Response to Colony-stimulating Factor-1 Requires Mitogen-activated Protein Kinase Kinase-1
1999 274: 6553-6558. [Abstract] [Full Text] [PDF]

Annette Gilchrist, Moritz Bünemann, Anli Li, M. Marlene Hosey, and Heidi E. Hamm

A Dominant-Negative Strategy for Studying Roles of G Proteins in Vivo
1999 274: 6610-6616. [Abstract] [Full Text] [PDF]

Hindupur K. Anandatheerthavarada, C. Vijayasarathy, Shripad V. Bhagwat, Gopa Biswas, Jayati Mullick, and Narayan G. Avadhani

Physiological Role of the N-terminal Processed P4501A1 Targeted to Mitochondria in Erythromycin Metabolism and Reversal of Erythromycin-mediated Inhibition of Mitochondrial Protein Synthesis
1999 274: 6617-6625. [Abstract] [Full Text] [PDF]

Eduardo Guillen, Claudia Abeijon, and Carlos B. Hirschberg

The Genes for the Golgi Apparatus N-Acetylglucosaminyltransferase and the UDP-N-acetylglucosamine Transporter Are Contiguous in Kluyveromyces lactis
1999 274: 6641-6646. [Abstract] [Full Text] [PDF]

Yasue Yamada, Yasuyo Chochi, Kougo Takamiya, Kenji Sobue, and Makoto Inui

Modulation of the Channel Activity of the 2/1-Subtype N-Methyl D-Aspartate Receptor by PSD-95
1999 274: 6647-6652. [Abstract] [Full Text] [PDF]

Eliana M. Coccia, Nadia Passini, Angela Battistini, Carlo Pini, Francesco Sinigaglia, and Lars Rogge

Interleukin-12 Induces Expression of Interferon Regulatory Factor-1 via Signal Transducer and Activator of Transcription-4 in Human T Helper Type 1 Cells
1999 274: 6698-6703. [Abstract] [Full Text] [PDF]

Sandra M. Leal, Shuan Shian Huang, and Jung San Huang

Interactions of High Affinity Insulin-like Growth Factor-binding Proteins with the Type V Transforming Growth Factor- Receptor in Mink Lung Epithelial Cells
1999 274: 6711-6717. [Abstract] [Full Text] [PDF]

Joel Berger, Mark D. Leibowitz, Thomas W. Doebber, Alex Elbrecht, Bei Zhang, Gaochou Zhou, Chhabi Biswas, Catherine A. Cullinan, Nancy S. Hayes, Ying Li, Michael Tanen, John Ventre, Margaret S. Wu, Gregory D. Berger, Ralph Mosley, Robert Marquis, Conrad Santini, Soumya P. Sahoo, Richard L. Tolman, Roy G. Smith, and David E. Moller

Novel Peroxisome Proliferator-activated Receptor (PPAR)  and PPAR Ligands Produce Distinct Biological Effects
1999 274: 6718-6725. [Abstract] [Full Text] [PDF]

Masahiro Tsuchida, Stuart J. Knechtle, and Majed M. Hamawy

CD28 Ligation Induces Tyrosine Phosphorylation of Pyk2 but Not Fak in Jurkat T Cells
1999 274: 6735-6740. [Abstract] [Full Text] [PDF]

Maria Thuveson and Erik Fries

Intracellular Proteolytic Processing of the Heavy Chain of Rat Pre--inhibitor. THE COOH-TERMINAL PROPEPTIDE IS REQUIRED FOR COUPLING TO BIKUNIN
1999 274: 6741-6746. [Abstract] [Full Text] [PDF]

Cong Li, Fredric B. Kraemer, Thomas E. Ahlborn, and Jingwen Liu

Induction of Low Density Lipoprotein Receptor (LDLR) Transcription by Oncostatin M Is Mediated by the Extracellular Signal-regulated Kinase Signaling Pathway and the Repeat 3 Element of the LDLR Promoter
1999 274: 6747-6753. [Abstract] [Full Text] [PDF]

Slavisa Gasic, Bing Tian, and Allan Green

Tumor Necrosis Factor  Stimulates Lipolysis in Adipocytes by Decreasing G_i Protein Concentrations
1999 274: 6770-6775. [Abstract] [Full Text] [PDF]

Nathalie Franchimont, Deena Durant, Sheila Rydziel, and Ernesto Canalis

Platelet-derived Growth Factor Induces Interleukin-6 Transcription in Osteoblasts through the Activator Protein-1 Complex and Activating Transcription Factor-2
1999 274: 6783-6789. [Abstract] [Full Text] [PDF]

Pierre Turpin, Ronald T. Hay, and Catherine Dargemont

Characterization of IB Nuclear Import Pathway
1999 274: 6804-6812. [Abstract] [Full Text] [PDF]

Enzymology

Alexander Schrem, Christian Lange, Michael Beyermann, and Karl-Wilhelm Koch

Identification of a Domain in Guanylyl Cyclase-activating Protein 1 That Interacts with a Complex of Guanylyl Cyclase and Tubulin in Photoreceptors
1999 274: 6244-6249. [Abstract] [Full Text] [PDF]

Richard L. Kendall, Ruth Z. Rutledge, Xianzhi Mao, Andrew J. Tebben, Randall W. Hungate, and Kenneth A. Thomas

Vascular Endothelial Growth Factor Receptor KDR Tyrosine Kinase Activity Is Increased by Autophosphorylation of Two Activation Loop Tyrosine Residues
1999 274: 6453-6460. [Abstract] [Full Text] [PDF]

Kent Lai, Amy C. Willis, and Louis J. Elsas

The Biochemical Role of Glutamine 188 in Human Galactose-1-phosphate Uridyltransferase
1999 274: 6559-6566. [Abstract] [Full Text] [PDF]

Elizabeth C. Arner, Michael A. Pratta, James M. Trzaskos, Carl P. Decicco, and Micky D. Tortorella

Generation and Characterization of Aggrecanase. A SOLUBLE, CARTILAGE-DERIVED AGGRECAN-DEGRADING ACTIVITY
1999 274: 6594-6601. [Abstract] [Full Text] [PDF]

John M. Louis, Stephen Oroszlan, and József Tözsér

Stabilization from Autoproteolysis and Kinetic Characterization of the Human T-cell Leukemia Virus Type 1 Proteinase
1999 274: 6660-6666. [Abstract] [Full Text] [PDF]

Jun Xu, Naomi L. Esmon, and Charles T. Esmon

Reconstitution of the Human Endothelial Cell Protein C Receptor with Thrombomodulin in Phosphatidylcholine Vesicles Enhances Protein C Activation
1999 274: 6704-6710. [Abstract] [Full Text] [PDF]

Chien-an A. Hu, Wei-Wen Lin, Cassandra Obie, and David Valle

Molecular Enzymology of Mammalian ¹-Pyrroline-5-carboxylate Synthase. ALTERNATIVE SPLICE DONOR UTILIZATION GENERATES ISOFORMS WITH DIFFERENT SENSITIVITY TO ORNITHINE INHIBITION
1999 274: 6754-6762. [Abstract] [Full Text] [PDF]

Pia Annunen, Peppi Koivunen, and Kari I. Kivirikko

Cloning of the  Subunit of Prolyl 4-Hydroxylase from Drosophila and Expression and Characterization of the Corresponding Enzyme Tetramer with Some Unique Properties
1999 274: 6790-6796. [Abstract] [Full Text] [PDF]

Membranes and Bioenergetics

Patrick G. Gallagher, Denise E. Sabatino, Marc Romana, Amanda P. Cline, Lisa J. Garrett, David M. Bodine, and Bernard G. Forget

A Human -Spectrin Gene Promoter Directs High Level Expression in Erythroid but Not Muscle or Neural Cells
1999 274: 6062-6073. [Abstract] [Full Text] [PDF]

Pedram Ghafourifar, Sabine D. Klein, Olivier Schucht, Ursula Schenk, Martin Pruschy, Sonia Rocha, and Christoph Richter

Ceramide Induces Cytochrome c Release from Isolated Mitochondria. IMPORTANCE OF MITOCHONDRIAL REDOX STATE
1999 274: 6080-6084. [Abstract] [Full Text] [PDF]

Wenshan Hao and Henry K. W. Fong

The Endogenous Chromophore of Retinal G Protein-coupled Receptor Opsin from the Pigment Epithelium
1999 274: 6085-6090. [Abstract] [Full Text] [PDF]

Regula Gutknecht, Karin Flükiger, Regina Lanz, and Bernhard Erni

Mechanism of Phosphoryl Transfer in the Dimeric IIAB^Man Subunit of the Escherichia coli Mannose Transporter
1999 274: 6091-6096. [Abstract] [Full Text] [PDF]

Véronique Leblais, Sophie Demolombe, Geneviève Vallette, Dominique Langin, Isabelle Baró, Denis Escande, and Chantal Gauthier

₃-Adrenoceptor Control the Cystic Fibrosis Transmembrane Conductance Regulator through a cAMP/Protein Kinase A-independent Pathway
1999 274: 6107-6113. [Abstract] [Full Text] [PDF]

Jason A. Hall, Mon-Chou Fann, and Peter C. Maloney

Altered Substrate Selectivity in a Mutant of an Intrahelical Salt Bridge in UhpT, the Sugar Phosphate Carrier of Escherichia coli
1999 274: 6148-6153. [Abstract] [Full Text] [PDF]

Jawed Hamid, Donald Nelson, Renee Spaetgens, Stefan J. Dubel, Terry P. Snutch, and Gerald W. Zamponi

Identification of an Integration Center for Cross-talk between Protein Kinase C and G Protein Modulation of N-type Calcium Channels
1999 274: 6195-6202. [Abstract] [Full Text] [PDF]

Elaine F. Corbett, Kim Oikawa, Patrice Francois, Daniel C. Tessier, Cyril Kay, John J. M. Bergeron, David Y. Thomas, Karl-Heinz Krause, and Marek Michalak

Ca²⁺ Regulation of Interactions between Endoplasmic Reticulum Chaperones
1999 274: 6203-6211. [Abstract] [Full Text] [PDF]

Charles Affourtit, Mary S. Albury, Klaas Krab, and Anthony L. Moore

Functional Expression of the Plant Alternative Oxidase Affects Growth of the Yeast Schizosaccharomyces pombe
1999 274: 6212-6218. [Abstract] [Full Text] [PDF]

Kathleen A. Kennedy and Beth Traxler

MalK Forms a Dimer Independent of Its Assembly into the MalFGK₂ ATP-binding Cassette Transporter of Escherichia coli
1999 274: 6259-6264. [Abstract] [Full Text] [PDF]

Makoto Suzuki, Junichi Sato, Keiko Kutsuwada, Gaku Ooki, and Masashi Imai

Cloning of a Stretch-inhibitable Nonselective Cation Channel
1999 274: 6330-6335. [Abstract] [Full Text] [PDF]

Ola Fjellström, Magnus Axelsson, Tania Bizouarn, Xiang Hu, Carina Johansson, Johan Meuller, and Jan Rydström

Mapping of Residues in the NADP(H)-binding Site of Proton-translocating Nicotinamide Nucleotide Transhydrogenase from Escherichia coli. A STUDY OF STRUCTURE AND FUNCTION
1999 274: 6350-6359. [Abstract] [Full Text] [PDF]

Jonathan L. McMurry and Debra A. Kendall

An Artificial Transmembrane Segment Directs SecA, SecB, and Electrochemical Potential-dependent Translocation of a Long Amino-terminal Tail
1999 274: 6776-6782. [Abstract] [Full Text] [PDF]

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Sergei Luchin, Harald Putzer, John W. B. Hershey, Yves Cenatiempo, Marianne Grunberg-Manago, and Soumaya Laalami

In Vitro Study of Two Dominant Inhibitory GTPase Mutants of Escherichia coli Translation Initiation Factor IF2. DIRECT EVIDENCE THAT GTP HYDROLYSIS IS NECESSARY FOR FACTOR RECYCLING
1999 274: 6074-6079. [Abstract] [Full Text] [PDF]

Masafumi Kida, Masayoshi Souri, Masayuki Yamamoto, Hidehiko Saito, and Akitada Ichinose

Transcriptional Regulation of Cell Type-specific Expression of the TATA-less A Subunit Gene for Human Coagulation Factor XIII
1999 274: 6138-6147. [Abstract] [Full Text] [PDF]

Stanislav Berjukow, Franz Gapp, Stefan Aczél, Martina J. Sinnegger, Joerg Mitterdorfer, Hartmut Glossmann, and Steffen Hering

Sequence Differences between _1C and _1S Ca²⁺ Channel Subunits Reveal Structural Determinants of a Guarded and Modulated Benzothiazepine Receptor
1999 274: 6154-6160. [Abstract] [Full Text] [PDF]

Hidetaka Torigoe, Anwarul Ferdous, Hiromitsu Watanabe, Toshihiro Akaike, and Atsushi Maruyama

Poly(L-lysine)-graft-dextran Copolymer Promotes Pyrimidine Motif Triplex DNA Formation at Physiological pH. THERMODYNAMIC AND KINETIC STUDIES
1999 274: 6161-6167. [Abstract] [Full Text] [PDF]

Chapla Agarwal, Tatiana Efimova, Jean F. Welter, James F. Crish, and Richard L. Eckert

CCAAT/Enhancer-binding Proteins. A ROLE IN REGULATION OF HUMAN INVOLUCRIN PROMOTER RESPONSE TO PHORBOL ESTER
1999 274: 6190-6194. [Abstract] [Full Text] [PDF]

Niels H. Gehring, Matthias W. Hentze, and Kostas Pantopoulos

Inactivation of Both RNA Binding and Aconitase Activities of Iron Regulatory Protein-1 by Quinone-induced Oxidative Stress
1999 274: 6219-6225. [Abstract] [Full Text] [PDF]

Paul J. Holzfeind, Helen J. Ambrose, Sarah E. Newey, Ralph A. Nawrotzki, Derek J. Blake, and Kay E. Davies

Tissue-selective Expression of -Dystrobrevin Is Determined by Multiple Promoters
1999 274: 6250-6258. [Abstract] [Full Text] [PDF]

Chandramohan V. Ammini and William W. Hauswirth

Mitochondrial Gene Expression Is Regulated at the Level of Transcription during Early Embryogenesis of Xenopus laevis
1999 274: 6265-6271. [Abstract] [Full Text] [PDF]

Lisa M. Brown, Brandon J. Burbach, Bruce A. McKenzie, and Gregory J. Connell

A Cis-acting A-U Sequence Element Induces Kinetoplastid U-insertions
1999 274: 6295-6304. [Abstract] [Full Text] [PDF]

Laurent Perrin, Pascale Romby, Patrick Laurenti, Hélène Bérenger, Sacha Kallenbach, Henry-Marc Bourbon, and Jacques Pradel

The Drosophila Modifier of Variegation modulo Gene Product Binds Specific RNA Sequences at the Nucleolus and Interacts with DNA and Chromatin in a Phosphorylation-dependent Manner
1999 274: 6315-6323. [Abstract] [Full Text] [PDF]

Shawn Guerrette, Samir Acharya, and Richard Fishel

The Interaction of the Human MutL Homologues in Hereditary Nonpolyposis Colon Cancer
1999 274: 6336-6341. [Abstract] [Full Text] [PDF]

José R. Pedrajas, Effie Kosmidou, Antonio Miranda-Vizuete, Jan-Åke Gustafsson, Anthony P. H. Wright, and Giannis Spyrou

Identification and Functional Characterization of a Novel Mitochondrial Thioredoxin System in Saccharomyces cerevisiae
1999 274: 6366-6373. [Abstract] [Full Text] [PDF]

Jesse C. Wiley, Lauren A. Wailes, Rejean L. Idzerda, and G. Stanley McKnight

Role of Regulatory Subunits and Protein Kinase Inhibitor (PKI) in Determining Nuclear Localization and Activity of the Catalytic Subunit of Protein Kinase A
1999 274: 6381-6387. [Abstract] [Full Text] [PDF]

Jack T. Rogers, Lorene M. Leiter, Jay McPhee, Catherine M. Cahill, Shan-Shan Zhan, Huntington Potter, and Lars N. G. Nilsson

Translation of the Alzheimer Amyloid Precursor Protein mRNA Is Up-regulated by Interleukin-1 through 5'-Untranslated Region Sequences
1999 274: 6421-6431. [Abstract] [Full Text] [PDF]

Akira Kobayashi, Etsuro Ito, Tsutomu Toki, Keiji Kogame, Shinichiro Takahashi, Kazuhiko Igarashi, Norio Hayashi, and Masayuki Yamamoto

Molecular Cloning and Functional Characterization of a New Cap'n' Collar Family Transcription Factor Nrf3
1999 274: 6443-6452. [Abstract] [Full Text] [PDF]

Daniel Pinto, Sylvie Robine, Frédéric Jaisser, Fatima El Marjou, and Daniel Louvard

Regulatory Sequences of the Mouse Villin Gene That Efficiently Drive Transgenic Expression in Immature and Differentiated Epithelial Cells of Small and Large Intestines
1999 274: 6476-6482. [Abstract] [Full Text] [PDF]

Dieder Moechars, Ilse Dewachter, Kristin Lorent, Delphine Reversé, Veerle Baekelandt, Asha Naidu, Ina Tesseur, Kurt Spittaels, Chris Van Den Haute, Fréderic Checler, Emile Godaux, Barbara Cordell, and Fred Van Leuven

Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain
1999 274: 6483-6492. [Abstract] [Full Text] [PDF]

Chun-Hyung Kim, Hee-Sun Kim, Joseph F. Cubells, and Kwang-Soo Kim

A Previously Undescribed Intron and Extensive 5' Upstream Sequence, but Not Phox2a-mediated Transactivation, Are Necessary for High Level Cell Type-specific Expression of the Human Norepinephrine Transporter Gene
1999 274: 6507-6518. [Abstract] [Full Text] [PDF]

Mayra Paolillo, Antonio Feliciello, Antonio Porcellini, Corrado Garbi, Maurizio Bifulco, Sergio Schinelli, Carmelo Ventra, Eugenio Stabile, Gaetano Ricciardelli, Gennaro Schettini, and Enrico V. Avvedimento

The Type and the Localization of cAMP-dependent Protein Kinase Regulate Transmission of cAMP Signals to the Nucleus in Cortical and Cerebellar Granule Cells
1999 274: 6546-6552. [Abstract] [Full Text] [PDF]

Jean-Marc Grégoire and Paul-Henri Roméo

T-cell Expression of the Human GATA-3 Gene Is Regulated by a Non-lineage-specific Silencer
1999 274: 6567-6578. [Abstract] [Full Text] [PDF]

Julie Lamontagne and Barbara Papadopoulou

Developmental Regulation of Spliced Leader RNA Gene in Leishmania donovani Amastigotes Is Mediated by Specific Polyadenylation
1999 274: 6602-6609. [Abstract] [Full Text] [PDF]

Vicente Díaz, Fernando Rojo, Carlos Martínez-A, Juan C. Alonso, and Antonio Bernad

The Prokaryotic -Recombinase Catalyzes Site-specific Recombination in Mammalian Cells
1999 274: 6634-6640. [Abstract] [Full Text] [PDF]

Eckardt Treuter, Lotta Johansson, Jane S. Thomsen, Anette Wärnmark, Jörg Leers, Markku Pelto-Huikko, Maria Sjöberg, Anthony P. H. Wright, Giannis Spyrou, and Jan-Åke Gustafsson

Competition between Thyroid Hormone Receptor-associated Protein (TRAP) 220 and Transcriptional Intermediary Factor (TIF) 2 for Binding to Nuclear Receptors. IMPLICATIONS FOR THE RECRUITMENT OF TRAP AND p160 COACTIVATOR COMPLEXES
1999 274: 6667-6677. [Abstract] [Full Text] [PDF]

Ian Grainge and David J. Sherratt

Xer Site-specific Recombination. DNA STRAND REJOINING BY RECOMBINASE XerC
1999 274: 6763-6769. [Abstract] [Full Text] [PDF]

Protein Chemistry and Structure

Amjad Farooq, Olga Plotnikova, Lei Zeng, and Ming-Ming Zhou

Phosphotyrosine Binding Domains of Shc and Insulin Receptor Substrate 1 Recognize the NPXpY Motif in a Thermodynamically Distinct Manner
1999 274: 6114-6121. [Abstract] [Full Text] [PDF]

Debra L. Becker, James C. Fredenburgh, Alan R. Stafford, and Jeffrey I. Weitz

Exosites 1 and 2 Are Essential for Protection of Fibrin-bound Thrombin from Heparin-catalyzed Inhibition by Antithrombin and Heparin Cofactor II
1999 274: 6226-6233. [Abstract] [Full Text] [PDF]

Irina Gutsche-Perelroizen, Jean Lepault, Albrecht Ott, and Marie-France Carlier

Filament Assembly from Profilin-Actin
1999 274: 6234-6243. [Abstract] [Full Text] [PDF]

Sigridur Olafsdottir and Aurora Martínez

The Accessibility of Iron at the Active Site of Recombinant Human Phenylalanine Hydroxylase to Water As Studied by ¹H NMR Paramagnetic Relaxation. EFFECT OF L-PHE AND COMPARISON WITH THE RAT ENZYME
1999 274: 6280-6284. [Abstract] [Full Text] [PDF]

Anderee R. Berengian, Maria Parfenova, and Hassane S. Mchaourab

Site-directed Spin Labeling Study of Subunit Interactions in the -Crystallin Domain of Small Heat-shock Proteins. COMPARISON OF THE OLIGOMER SYMMETRY IN A-CRYSTALLIN, HSP 27, and HSP 16.3
1999 274: 6305-6314. [Abstract] [Full Text] [PDF]

Anders Lindblom, Natascha Quadt, Tracey Marsh, Daniel Aeschlimann, Matthias Mörgelin, Karlheinz Mann, Patrik Maurer, and Mats Paulsson

The Intrinsic Factor-Vitamin B₁₂ Receptor, Cubilin, Is Assembled into Trimers via a Coiled-coil -Helix
1999 274: 6374-6380. [Abstract] [Full Text] [PDF]

Malin Svensson, Hemant Sabharwal, Anders Håkansson, Ann-Kristin Mossberg, Peter Lipniunas, Hakon Leffler, Catharina Svanborg, and Sara Linse

Molecular Characterization of -Lactalbumin Folding Variants That Induce Apoptosis in Tumor Cells
1999 274: 6388-6396. [Abstract] [Full Text] [PDF]

Dirk Schnappinger, Peter Schubert, Christian Berens, Klaus Pfleiderer, and Wolfgang Hillen

Solvent-exposed Residues in the Tet repressor (TetR) Four-helix Bundle Contribute to Subunit Recognition and Dimer Stability
1999 274: 6405-6410. [Abstract] [Full Text] [PDF]

James E. Knapp, Marcos A. Oliveira, Qiang Xie, Stephen R. Ernst, Austen F. Riggs, and Marvin L. Hackert

The Structural and Functional Analysis of the Hemoglobin D Component from Chicken
1999 274: 6411-6420. [Abstract] [Full Text] [PDF]

Angelia D. Gibson, John A. Lamerdin, Ping Zhuang, Kunnumal Baburaj, Engin H. Serpersu, and Cynthia B. Peterson

Orientation of Heparin-binding Sites in Native Vitronectin. ANALYSES OF LIGAND BINDING TO THE PRIMARY GLYCOSAMINOGLYCAN-BINDING SITE INDICATE THAT PUTATIVE SECONDARY SITES ARE NOT FUNCTIONAL
1999 274: 6432-6442. [Abstract] [Full Text] [PDF]

Amelia S. Edwards, Maree C. Faux, John D. Scott, and Alexandra C. Newton

Carboxyl-terminal Phosphorylation Regulates the Function and Subcellular Localization of Protein Kinase C II
1999 274: 6461-6468. [Abstract] [Full Text] [PDF]

Shigeki Miyata and Zaverio M. Ruggeri

Distinct Structural Attributes Regulating von Willebrand Factor A1 Domain Interaction with Platelet Glycoprotein Ib under Flow
1999 274: 6586-6593. [Abstract] [Full Text] [PDF]

Jocelyne Fujinaga, Xiao-Bo Tang, and Joseph R. Casey

Topology of the Membrane Domain of Human Erythrocyte Anion Exchange Protein, AE1
1999 274: 6626-6633. [Abstract] [Full Text] [PDF]

Gonzalo E. Torres, Terrance M. Egan, and Mark M. Voigt

Hetero-oligomeric Assembly of P2X Receptor Subunits. SPECIFICITIES EXIST WITH REGARD TO POSSIBLE PARTNERS
1999 274: 6653-6659. [Abstract] [Full Text] [PDF]

Robert M. Bookchin, Tania Balazs, Zhiping Wang, Robert Josephs, and Virgilio L. Lew

Polymer Structure and Solubility of Deoxyhemoglobin S in the Presence of High Concentrations of Volume-excluding 70-kDa Dextran. EFFECTS OF NON-S HEMOGLOBINS AND INHIBITORS
1999 274: 6689-6697. [Abstract] [Full Text] [PDF]

Waldemar Vollmer, Moritz von Rechenberg, and Joachim-Volker Höltje

Demonstration of Molecular Interactions between the Murein Polymerase PBP1B, the Lytic Transglycosylase MltA, and the Scaffolding Protein MipA of Escherichia coli
1999 274: 6726-6734. [Abstract] [Full Text] [PDF]

Fred K. Hagen, Bart Hazes, Roberto Raffo, Deborah deSa, and Lawrence A. Tabak

Structure-Function Analysis of the UDP-N-acetyl-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase. ESSENTIAL RESIDUES LIE IN A PREDICTED ACTIVE SITE CLEFT RESEMBLING A LACTOSE REPRESSOR FOLD
1999 274: 6797-6803. [Abstract] [Full Text] [PDF]

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