Minireviews

Carlos Bustamante, Martin Guthold, Xingshu Zhu, and Guoliang Yang

Facilitated Target Location on DNA by Individual Escherichia coli RNA Polymerase Molecules Observed with the Scanning Force Microscope Operating in Liquid
1999 274: 16665-16668. [Full Text] [PDF]

Communications

David E. Coleman and Stephen R. Sprang

Structure of G_i1·GppNHp, Autoinhibition in a G Protein-Substrate Complex
1999 274: 16669-16672. [Abstract] [Full Text] [PDF]

Sang Gyu Park, Keum Hee Jung, Jong Sang Lee, Yeong Joon Jo, Hiromi Motegi, Sunghoon Kim, and Kiyotaka Shiba

Precursor of Pro-apoptotic Cytokine Modulates Aminoacylation Activity of tRNA Synthetase
1999 274: 16673-16676. [Abstract] [Full Text] [PDF]

Shin-ichi Hoshino, Mariko Imai, Tetsuo Kobayashi, Naoyuki Uchida, and Toshiaki Katada

The Eukaryotic Polypeptide Chain Releasing Factor (eRF3/GSPT) Carrying the Translation Termination Signal to the 3'-Poly(A) Tail of mRNA. DIRECT ASSOCIATION OF eRF3/GSPT WITH POLYADENYLATE-BINDING PROTEIN
1999 274: 16677-16680. [Abstract] [Full Text] [PDF]

Vadim Gaponenko, Ekram Abusamhadneh, M. Bret Abbott, Natosha Finley, Genevieve Gasmi-Seabrook, R. John Solaro, Mark Rance, and Paul R. Rosevear

Effects of Troponin I Phosphorylation on Conformational Exchange in the Regulatory Domain of Cardiac Troponin C
1999 274: 16681-16684. [Abstract] [Full Text] [PDF]

Carbohydrates, Lipids, and Other Natural Products

Minoru Ujita, Joseph McAuliffe, Ole Hindsgaul, Katsutoshi Sasaki, Michiko N. Fukuda, and Minoru Fukuda

Poly-N-acetyllactosamine Synthesis in Branched N-Glycans Is Controlled by Complemental Branch Specificity of i-Extension Enzyme and 1,4-Galactosyltransferase I
1999 274: 16717-16726. [Abstract] [Full Text] [PDF]

Sabine Rund, Buko Lindner, Helmut Brade, and Otto Holst

Structural Analysis of the Lipopolysaccharide from Chlamydia trachomatis Serotype L2
1999 274: 16819-16824. [Abstract] [Full Text] [PDF]

Jun Gao and Ginette Serrero

Adipose Differentiation Related Protein (ADRP) Expressed in Transfected COS-7 Cells Selectively Stimulates Long Chain Fatty Acid Uptake
1999 274: 16825-16830. [Abstract] [Full Text] [PDF]

Yasushi Shimoda, Youichi Tajima, Takashi Nagase, Kiyonori Harii, Noriko Osumi, and Yutaka Sanai

Cloning and Expression of a Novel Galactoside 1,3-Glucuronyltransferase Involved in the Biosynthesis of HNK-1 Epitope
1999 274: 17115-17122. [Abstract] [Full Text] [PDF]

Soo Kyung Oh, Hunseung Kang, Dong Ho Shin, Jaemo Yang, Keng-See Chow, Hoong Yeet Yeang, Birgit Wagner, Heimo Breiteneder, and Kyung-Hwan Han

Isolation, Characterization, and Functional Analysis of a Novel cDNA Clone Encoding a Small Rubber Particle Protein from Hevea brasiliensis
1999 274: 17132-17138. [Abstract] [Full Text] [PDF]

Roland Knauer and Ludwig Lehle

The Oligosaccharyltransferase Complex from Saccharomyces cerevisiae. ISOLATION OF THE OST6 GENE, ITS SYNTHETIC INTERACTION WITH OST3, AND ANALYSIS OF THE NATIVE COMPLEX
1999 274: 17249-17256. [Abstract] [Full Text] [PDF]

Cell Biology and Metabolism

Andrzej J. Chruscinski, Daniel K. Rohrer, Eric Schauble, Kavin H. Desai, Daniel Bernstein, and Brian K. Kobilka

Targeted Disruption of the 2 Adrenergic Receptor Gene
1999 274: 16694-16700. [Abstract] [Full Text] [PDF]

Daniel K. Rohrer, Andrzej Chruscinski, Eric H. Schauble, Daniel Bernstein, and Brian K. Kobilka

Cardiovascular and Metabolic Alterations in Mice Lacking Both 1- and 2-Adrenergic Receptors
1999 274: 16701-16708. [Abstract] [Full Text] [PDF]

Ana Rodríguez, Iñigo Martinez, Albert Chung, Catherine H. Berlot, and Norma W. Andrews

cAMP Regulates Ca²⁺-dependent Exocytosis of Lysosomes and Lysosome-mediated Cell Invasion by Trypanosomes
1999 274: 16754-16759. [Abstract] [Full Text] [PDF]

Sally Corradin, Jacques Mauël, Adriana Ransijn, Christoph Stürzinger, and Guy Vergères

Down-regulation of MARCKS-related Protein (MRP) in Macrophages Infected with Leishmania
1999 274: 16782-16787. [Abstract] [Full Text] [PDF]

Louise Deltour, Mario H. Foglio, and Gregg Duester

Metabolic Deficiencies in Alcohol Dehydrogenase Adh1, Adh3, and Adh4 Null Mutant Mice. OVERLAPPING ROLES OF Adh1 AND Adh4 IN ETHANOL CLEARANCE AND METABOLISM OF RETINOL TO RETINOIC ACID
1999 274: 16796-16801. [Abstract] [Full Text] [PDF]

Lothar Goretzki, Michael A. Burg, Kathryn A. Grako, and William B. Stallcup

High-affinity Binding of Basic Fibroblast Growth Factor and Platelet-derived Growth Factor-AA to the Core Protein of the NG2 Proteoglycan
1999 274: 16831-16837. [Abstract] [Full Text] [PDF]

David R. Jones, Trevor R. Pettitt, Miguel A. Sanjuán, Isabel Mérida, and Michael J. O. Wakelam

Interleukin-2 Causes an Increase in Saturated/Monounsaturated Phosphatidic Acid Derived from 1,2-Diacylglycerol and 1-O-Alkyl-2-acylglycerol
1999 274: 16846-16852. [Abstract] [Full Text] [PDF]

Tamara J. Richman, Mathew M. Sawyer, and Douglas I. Johnson

The Cdc42p GTPase Is Involved in a G₂/M Morphogenetic Checkpoint Regulating the Apical-Isotropic Switch and Nuclear Division in Yeast
1999 274: 16861-16870. [Abstract] [Full Text] [PDF]

Xiaoqing Sun, James Lee, Tony Navas, Daryl T. Baldwin, Timothy A. Stewart, and Vishva M. Dixit

RIP3, a Novel Apoptosis-inducing Kinase
1999 274: 16871-16875. [Abstract] [Full Text] [PDF]

Jukka Y. A. Lehtonen, Masatsugu Horiuchi, Laurent Daviet, Masahiro Akishita, and Victor J. Dzau

Activation of the de novo Biosynthesis of Sphingolipids Mediates Angiotensin II Type 2 Receptor-induced Apoptosis
1999 274: 16901-16906. [Abstract] [Full Text] [PDF]

Fernando A. Arosa, Orlando de Jesus, Graça Porto, Alexandre M. Carmo, and Maria de Sousa

Calreticulin Is Expressed on the Cell Surface of Activated Human Peripheral Blood T Lymphocytes in Association with Major Histocompatibility Complex Class I Molecules
1999 274: 16917-16922. [Abstract] [Full Text] [PDF]

David A. Diamond, Azemat Parsian, Clayton R. Hunt, Sam Lofgren, Douglas R. Spitz, Prabhat C. Goswami, and David Gius

Redox Factor-1 (Ref-1) Mediates the Activation of AP-1 in HeLa and NIH 3T3 Cells in Response to Heat Shock
1999 274: 16959-16964. [Abstract] [Full Text] [PDF]

Maria Felice Brizzi, Patrizia Dentelli, Arturo Rosso, Yosef Yarden, and Luigi Pegoraro

STAT Protein Recruitment and Activation in c-Kit Deletion Mutants
1999 274: 16965-16972. [Abstract] [Full Text] [PDF]

Anikó Náray-Fejes-Tóth, Cecilia Canessa, Emily S. Cleaveland, George Aldrich, and Géza Fejes-Tóth

sgk Is an Aldosterone-induced Kinase in the Renal Collecting Duct. EFFECTS ON EPITHELIAL Na⁺ CHANNELS
1999 274: 16973-16978. [Abstract] [Full Text] [PDF]

Noriaki Shinobu, Tatsuya Maeda, Teijiro Aso, Tohru Ito, Takuma Kondo, Katsuro Koike, and Masanori Hatakeyama

Physical Interaction and Functional Antagonism between the RNA Polymerase II Elongation Factor ELL and p53
1999 274: 17003-17010. [Abstract] [Full Text] [PDF]

Keith Ireton, Bernard Payrastre, and Pascale Cossart

The Listeria monocytogenes Protein InlB Is an Agonist of Mammalian Phosphoinositide 3-Kinase
1999 274: 17025-17032. [Abstract] [Full Text] [PDF]

David Bishop-Bailey and Timothy Hla

Endothelial Cell Apoptosis Induced by the Peroxisome Proliferator-activated Receptor (PPAR) Ligand 15-Deoxy-^12,14-prostaglandin J₂
1999 274: 17042-17048. [Abstract] [Full Text] [PDF]

Laurent Daviet, Jukka Y. A. Lehtonen, Kouichi Tamura, Daniel P. Griese, Masatsugu Horiuchi, and Victor J. Dzau

Cloning and Characterization of ATRAP, a Novel Protein That Interacts with the Angiotensin II Type 1 Receptor
1999 274: 17058-17062. [Abstract] [Full Text] [PDF]

Chuanzheng Song, Xiao Jia Chang, Kevin M. Bean, Mark S. Proia, John L. Knopf, and Ronald W. Kriz

Molecular Characterization of Cytosolic Phospholipase A₂-
1999 274: 17063-17067. [Abstract] [Full Text] [PDF]

Nobuhiro Sakata, J. Daniel Stoops, and Joseph L. Dixon

Cytosolic Components Are Required for Proteasomal Degradation of Newly Synthesized Apolipoprotein B in Permeabilized HepG2 Cells
1999 274: 17068-17074. [Abstract] [Full Text] [PDF]

Ron F. Morrison and Stephen R. Farmer

Role of PPAR in Regulating a Cascade Expression of Cyclin-dependent Kinase Inhibitors, p18(INK4c) and p21(Waf1/Cip1), during Adipogenesis
1999 274: 17088-17097. [Abstract] [Full Text] [PDF]

Avindra Nath, Katherine Conant, Peiqin Chen, Catherine Scott, and Eugene O. Major

Transient Exposure to HIV-1 Tat Protein Results in Cytokine Production in Macrophages and Astrocytes. A HIT AND RUN PHENOMENON
1999 274: 17098-17102. [Abstract] [Full Text] [PDF]

Gabriela Vaduva, Narcisa Martinez-Quiles, Ines M. Anton, Nancy C. Martin, Raif S. Geha, Anita K. Hopper, and Narayanaswamy Ramesh

The Human WASP-interacting Protein, WIP, Activates the Cell Polarity Pathway in Yeast
1999 274: 17103-17108. [Abstract] [Full Text] [PDF]

Sanjay Kumar, Annalisa T. Hand, Janice R. Connor, Robert A. Dodds, Paul J. Ryan, John J. Trill, Seth M. Fisher, Mark E. Nuttall, David B. Lipshutz, Cheng Zou, Shing M. Hwang, Bartholomew J. Votta, Ian E. James, David J. Rieman, Maxine Gowen, and John C. Lee

Identification and Cloning of a Connective Tissue Growth Factor-like cDNA from Human Osteoblasts Encoding a Novel Regulator of Osteoblast Functions
1999 274: 17123-17131. [Abstract] [Full Text] [PDF]

Sonja Krugmann, Phillip T. Hawkins, Nancy Pryer, and Sylvia Braselmann

Characterizing the Interactions between the Two Subunits of the p101/p110 Phosphoinositide 3-Kinase and Their Role in the Activation of This Enzyme by G Subunits
1999 274: 17152-17158. [Abstract] [Full Text] [PDF]

Julia K. Voice, Richard L. Klemke, Ann Le, and Janis H. Jackson

Four Human Ras Homologs Differ in Their Abilities to Activate Raf-1, Induce Transformation, and Stimulate Cell Motility
1999 274: 17164-17170. [Abstract] [Full Text] [PDF]

Graham Rena, Shaodong Guo, Stephen C. Cichy, Terry G. Unterman, and Philip Cohen

Phosphorylation of the Transcription Factor Forkhead Family Member FKHR by Protein Kinase B
1999 274: 17179-17183. [Abstract] [Full Text] [PDF]

Shaodong Guo, Graham Rena, Stephen Cichy, Xiaowei He, Philip Cohen, and Terry Unterman

Phosphorylation of Serine 256 by Protein Kinase B Disrupts Transactivation by FKHR and Mediates Effects of Insulin on Insulin-like Growth Factor-binding Protein-1 Promoter Activity through a Conserved Insulin Response Sequence
1999 274: 17184-17192. [Abstract] [Full Text] [PDF]

Karen Wright, George Kolios, John Westwick, and Stephen G. Ward

Cytokine-induced Apoptosis in Epithelial HT-29 Cells Is Independent of Nitric Oxide Formation. EVIDENCE FOR AN INTERLEUKIN-13-DRIVEN PHOSPHATIDYLINOSITOL 3-KINASE-DEPENDENT SURVIVAL MECHANISM
1999 274: 17193-17201. [Abstract] [Full Text] [PDF]

Xiang-Lan Yao, Mark J. Cowan, Mark T. Gladwin, Marion M. Lawrence, C. William Angus, and James H. Shelhamer

Dexamethasone Alters Arachidonate Release from Human Epithelial Cells by Induction of p11 Protein Synthesis and Inhibition of Phospholipase A₂ Activity
1999 274: 17202-17208. [Abstract] [Full Text] [PDF]

Monilola A. Olayioye, Iwan Beuvink, Kay Horsch, John M. Daly, and Nancy E. Hynes

ErbB Receptor-induced Activation of Stat Transcription Factors Is Mediated by Src Tyrosine Kinases
1999 274: 17209-17218. [Abstract] [Full Text] [PDF]

Laurent Vallar, Chantal Melchior, Sébastien Plançon, Hervé Drobecq, Guy Lippens, Véronique Regnault, and Nelly Kieffer

Divalent Cations Differentially Regulate Integrin _IIb Cytoplasmic Tail Binding to ₃ and to Calcium- and Integrin-binding Protein
1999 274: 17257-17266. [Abstract] [Full Text] [PDF]

Mikiko Takahashi, Hideki Shibata, Masaki Shimakawa, Masaaki Miyamoto, Hideyuki Mukai, and Yoshitaka Ono

Characterization of a Novel Giant Scaffolding Protein, CG-NAP, That Anchors Multiple Signaling Enzymes to Centrosome and the Golgi Apparatus
1999 274: 17267-17274. [Abstract] [Full Text] [PDF]

Jianrong Li, Christopher A. Bombeck, Sufang Yang, Young-Myeong Kim, and Timothy R. Billiar

Nitric Oxide Suppresses Apoptosis via Interrupting Caspase Activation and Mitochondrial Dysfunction in Cultured Hepatocytes
1999 274: 17325-17333. [Abstract] [Full Text] [PDF]

Lijie Sun, Tung-Tien Sun, and Robert M. Lavker

Identification of a Cytosolic NADP⁺-dependent Isocitrate Dehydrogenase That Is Preferentially Expressed in Bovine Corneal Epithelium. A CORNEAL EPITHELIAL CRYSTALLIN
1999 274: 17334-17341. [Abstract] [Full Text] [PDF]

Enzymology

Andreas Bracher, Markus Fischer, Wolfgang Eisenreich, Harald Ritz, Nicholas Schramek, Peter Boyle, Patrizia Gentili, Robert Huber, Herbert Nar, Günter Auerbach, and Adelbert Bacher

Histidine 179 Mutants of GTP Cyclohydrolase I Catalyze the Formation of 2-Amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone Triphosphate
1999 274: 16727-16735. [Abstract] [Full Text] [PDF]

Piotr Konczalik and Joel Moss

Identification of Critical, Conserved Vicinal Aspartate Residues in Mammalian and Bacterial ADP-ribosylarginine Hydrolases
1999 274: 16736-16740. [Abstract] [Full Text] [PDF]

Agnès Vié, Mireille Cigna, René Toci, and Serge Birman

Differential Regulation of Drosophila Tyrosine Hydroxylase Isoforms by Dopamine Binding and cAMP-dependent Phosphorylation
1999 274: 16788-16795. [Abstract] [Full Text] [PDF]

Yasuo Yoshida, Yoshio Nakano, Takashi Nezu, Yoshihisa Yamashita, and Toshihiko Koga

A Novel NDP-6-deoxyhexosyl-4-ulose Reductase in the Pathway for the Synthesis of Thymidine Diphosphate-D-fucose
1999 274: 16933-16939. [Abstract] [Full Text] [PDF]

Thomas B. Stanley, Da-Yun Jin, Pen-Jen Lin, and Darrel W. Stafford

The Propeptides of the Vitamin K-dependent Proteins Possess Different Affinities for the Vitamin K-dependent Carboxylase
1999 274: 16940-16944. [Abstract] [Full Text] [PDF]

Alain Roussel, Stéphane Canaan, Marie-Pierre Egloff, Mireille Rivière, Liliane Dupuis, Robert Verger, and Christian Cambillau

Crystal Structure of Human Gastric Lipase and Model of Lysosomal Acid Lipase, Two Lipolytic Enzymes of Medical Interest
1999 274: 16995-17002. [Abstract] [Full Text] [PDF]

Membranes and Bioenergetics

Ioulia Matskevitch, Carsten A. Wagner, Carola Stegen, Stefan Bröer, Birgitta Noll, Teut Risler, H. Moo Kwon, Joseph S. Handler, Siegfried Waldegger, Andreas E. Busch, and Florian Lang

Functional Characterization of the Betaine/-Aminobutyric Acid Transporter BGT-1 Expressed in Xenopus Oocytes
1999 274: 16709-16716. [Abstract] [Full Text] [PDF]

Amina Elbehti, Wolfgang Nitschke, Pascale Tron, Caroline Michel, and Danielle Lemesle-Meunier

Redox Components of Cytochrome bc-type Enzymes in Acidophilic Prokaryotes. I.  CHARACTERIZATION OF THE CYTOCHROME bc₁-TYPE COMPLEX OF THE ACIDOPHILIC FERROUS ION-OXIDIZING BACTERIUM THIOBACILLUS FERROOXIDANS
1999 274: 16760-16765. [Abstract] [Full Text] [PDF]

Myriam Brugna, Wolfgang Nitschke, Marcel Asso, Bruno Guigliarelli, Danielle Lemesle-Meunier, and Christian Schmidt

Redox Components of Cytochrome bc-type Enzymes in Acidophilic Prokaryotes. II. THE RIESKE PROTEIN OF PHYLOGENETICALLY DISTANT ACIDOPHILIC ORGANISMS
1999 274: 16766-16772. [Abstract] [Full Text] [PDF]

Joe Hermolin, Oleg Y. Dmitriev, Ying Zhang, and Robert H. Fillingame

Defining the Domain of Binding of F₁ Subunit  with the Polar Loop of F₀ Subunit c in the Escherichia coli ATP Synthase
1999 274: 17011-17016. [Abstract] [Full Text] [PDF]

Takaaki Abe, Masayuki Kakyo, Taro Tokui, Rie Nakagomi, Toshiyuki Nishio, Daisuke Nakai, Hideki Nomura, Michiaki Unno, Masanori Suzuki, Takeshi Naitoh, Seiki Matsuno, and Hiromu Yawo

Identification of a Novel Gene Family Encoding Human Liver-specific Organic Anion Transporter LST-1
1999 274: 17159-17163. [Abstract] [Full Text] [PDF]

Helen H. Cheng, Liwen Xu, Hidetoshi Kumagai, and Robert D. Simoni

Oligomerization State Influences the Degradation Rate of 3-Hydroxy-3-methylglutaryl-CoA Reductase
1999 274: 17171-17178. [Abstract] [Full Text] [PDF]

Patricia M. Kane, Maureen Tarsio, and Jianzhong Liu

Early Steps in Assembly of the Yeast Vacuolar H⁺-ATPase
1999 274: 17275-17283. [Abstract] [Full Text] [PDF]

Soufian Ouchane and Samuel Kaplan

Topological Analysis of the Membrane-localized Redox-responsive Sensor Kinase PrrB from Rhodobacter sphaeroides 2.4.1
1999 274: 17290-17296. [Abstract] [Full Text] [PDF]

Takashi Murayama, Toshiharu Oba, Eisaku Katayama, Hideto Oyamada, Katsuji Oguchi, Masakazu Kobayashi, Kazuyuki Otsuka, and Yasuo Ogawa

Further Characterization of the Type 3 Ryanodine Receptor (RyR3) Purified from Rabbit Diaphragm
1999 274: 17297-17308. [Abstract] [Full Text] [PDF]

Takaaki Wada, Julie C. Long, Di Zhang, and Steven B. Vik

A Novel Labeling Approach Supports the Five-transmembrane Model of Subunit a of the Escherichia coli ATP Synthase
1999 274: 17353-17357. [Abstract] [Full Text] [PDF]

Hans Merzendorfer, Markus Huss, Roland Schmid, William R. Harvey, and Helmut Wieczorek

A Novel Insect V-ATPase Subunit M9.7 Is Glycosylated Extensively
1999 274: 17372-17378. [Abstract] [Full Text] [PDF]

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Eric D. Tang, Gabriel Nuñez, Frederic G. Barr, and Kun-Liang Guan

Negative Regulation of the Forkhead Transcription Factor FKHR by Akt
1999 274: 16741-16746. [Abstract] [Full Text] [PDF]

Roberto Doliana, Maurizio Mongiat, Francesco Bucciotti, Emiliana Giacomello, Rainer Deutzmann, Dino Volpin, Giorgio M. Bressan, and Alfonso Colombatti

EMILIN, a Component of the Elastic Fiber and a New Member of the C1q/Tumor Necrosis Factor Superfamily of Proteins
1999 274: 16773-16781. [Abstract] [Full Text] [PDF]

Hans-Peter Vornlocher, Parisa Hanachi, Sofia Ribeiro, and John W. B. Hershey

A 110-Kilodalton Subunit of Translation Initiation Factor eIF3 and an Associated 135-kilodalton Protein Are Encoded by the Saccharomyces cerevisiae TIF32 and TIF31 Genes
1999 274: 16802-16812. [Abstract] [Full Text] [PDF]

Wen Yang and Leonard P. Freedman

20-Epi Analogues of 1,25-Dihydroxyvitamin D₃ Are Highly Potent Inducers of DRIP Coactivator Complex Binding to the Vitamin D₃ Receptor
1999 274: 16838-16845. [Abstract] [Full Text] [PDF]

Mehrdad Pedram and John E. Donelson

The Anatomy and Transcription of a Monocistronic Expression Site for a Metacyclic Variant Surface Glycoprotein Gene in Trypanosoma brucei
1999 274: 16876-16883. [Abstract] [Full Text] [PDF]

Clara M. Alarcon, Mehrdad Pedram, and John E. Donelson

Leaky Transcription of Variant Surface Glycoprotein Gene Expression Sites in Bloodstream African Trypanosomes
1999 274: 16884-16893. [Abstract] [Full Text] [PDF]

Huixian Wang, Christopher W. Lawrence, Guo-Min Li, and John B. Hays

Specific Binding of Human MSH2·MSH6 Mismatch-Repair Protein Heterodimers to DNA Incorporating Thymine- or Uracil-containing UV Light Photoproducts Opposite Mismatched Bases
1999 274: 16894-16900. [Abstract] [Full Text] [PDF]

Susanne Zimmermann, Alexander Baumann, Karsten Jaekel, Irit Marbach, David Engelberg, and Hanns Frohnmeyer

UV-responsive Genes of Arabidopsis Revealed by Similarity to the Gcn4-mediated UV Response in Yeast
1999 274: 17017-17024. [Abstract] [Full Text] [PDF]

Hiromitsu Tanaka, Yasuhide Yoshimura, Masami Nozaki, Kentaro Yomogida, Junji Tsuchida, Yasuhiro Tosaka, Toshiyuki Habu, Tomoko Nakanishi, Masato Okada, Hiroshi Nojima, and Yoshitake Nishimune

Identification and Characterization of a Haploid Germ Cell-specific Nuclear Protein Kinase (Haspin) in Spermatid Nuclei and Its Effects on Somatic Cells
1999 274: 17049-17057. [Abstract] [Full Text] [PDF]

Ilya Serebriiskii, Vladimir Khazak, and Erica A. Golemis

A Two-hybrid Dual Bait System to Discriminate Specificity of Protein Interactions
1999 274: 17080-17087. [Abstract] [Full Text] [PDF]

Sandeep Burma, Akihiro Kurimasa, Guofeng Xie, Yoichi Taya, Ryoko Araki, Masumi Abe, Harry A. Crissman, Honghai Ouyang, Gloria C. Li, and David J. Chen

DNA-dependent Protein Kinase-independent Activation of p53 in Response to DNA Damage
1999 274: 17139-17143. [Abstract] [Full Text] [PDF]

Angret Joester and Andreas Faissner

Evidence for Combinatorial Variability of Tenascin-C Isoforms and Developmental Regulation in the Mouse Central Nervous System
1999 274: 17144-17151. [Abstract] [Full Text] [PDF]

Phillip C. C. Liu and Dennis J. Thiele

Modulation of Human Heat Shock Factor Trimerization by the Linker Domain
1999 274: 17219-17225. [Abstract] [Full Text] [PDF]

Yan Kwok, Qingping Zeng, and Laurence H. Hurley

Structural Insight into a Quinolone-Topoisomerase II-DNA Complex. FURTHER EVIDENCE FOR A 2:2 QUINOBENZOXAZINE-Mg²⁺ SELF-ASSEMBLY MODEL FORMED IN THE PRESENCE OF TOPOISOMERASE II
1999 274: 17226-17235. [Abstract] [Full Text] [PDF]

Lun-Quan Sun, Murray J. Cairns, Wayne L. Gerlach, Craig Witherington, Li Wang, and Andrew King

Suppression of Smooth Muscle Cell Proliferation by a c-myc RNA-cleaving Deoxyribozyme
1999 274: 17236-17241. [Abstract] [Full Text] [PDF]

Akira Murakami, Jane Thurlow, and Clive Dickson

Retinoic Acid-regulated Expression of Fibroblast Growth Factor 3 Requires the Interaction between a Novel Transcription Factor and GATA-4
1999 274: 17242-17248. [Abstract] [Full Text] [PDF]

Géraldine Farjot, Alain Sergeant, and Ivan Mikaélian

A New Nucleoporin-like Protein Interacts with Both HIV-1 Rev Nuclear Export Signal and CRM-1
1999 274: 17309-17317. [Abstract] [Full Text] [PDF]

Tamás Henics, Eszter Nagy, Hyun Ju Oh, Péter Csermely, Alexander von Gabain, and John R. Subjeck

Mammalian Hsp70 and Hsp110 Proteins Bind to RNA Motifs Involved in mRNA Stability
1999 274: 17318-17324. [Abstract] [Full Text] [PDF]

Gopalswamy Jayaraman, Rampalli Srinivas, Catherine Duggan, Elisabeth Ferreira, Sathyamangalam Swaminathan, Kumaravel Somasundaram, Justin Williams, Craig Hauser, Markku Kurkinen, Ravi Dhar, Sigmund Weitzman, Giovanna Buttice, and Bayar Thimmapaya

p300/cAMP-responsive Element-binding Protein Interactions with Ets-1 and Ets-2 in the Transcriptional Activation of the Human Stromelysin Promoter
1999 274: 17342-17352. [Abstract] [Full Text] [PDF]

Hongmin Chen, Shui-Qing Wei, and Alan Engelman

Multiple Integrase Functions Are Required to Form the Native Structure of the Human Immunodeficiency Virus Type I Intasome
1999 274: 17358-17364. [Abstract] [Full Text] [PDF]

Qin Wang, Bashar K. Mullah, and Janet D. Robishaw

Ribozyme Approach Identifies a Functional Association between the G Protein ₁₇ Subunits in the -Adrenergic Receptor Signaling Pathway
1999 274: 17365-17371. [Abstract] [Full Text] [PDF]

Tomas Simonsson and Robert Sjöback

DNA Tetraplex Formation Studied with Fluorescence Resonance Energy Transfer
1999 274: 17379-17383. [Abstract] [Full Text] [PDF]

Giancarlo Ghiselli, Linda D. Siracusa, and Renato V. Iozzo

Complete cDNA Cloning, Genomic Organization, Chromosomal Assignment, Functional Characterization of the Promoter, and Expression of the Murine Bamacan Gene
1999 274: 17384-17393. [Abstract] [Full Text] [PDF]

Protein Chemistry and Structure

Paul C. White, Maria C. Cordeiro, Daniele Arnold, Peter E. Brodelius, and John Kay

Processing, Activity, and Inhibition of Recombinant Cyprosin, an Aspartic Proteinase from Cardoon (Cynara cardunculus)
1999 274: 16685-16693. [Abstract] [Full Text] [PDF]

Masahiro Hosaka and Thomas C. Südhof

Homo- and Heterodimerization of Synapsins
1999 274: 16747-16753. [Abstract] [Full Text] [PDF]

Ehud Gazit and Robert T. Sauer

The Doc Toxin and Phd Antidote Proteins of the Bacteriophage P1 Plasmid Addiction System Form a Heterotrimeric Complex
1999 274: 16813-16818. [Abstract] [Full Text] [PDF]

Julia Oosterom, Wouter A. J. Nijenhuis, Wim M. M. Schaaper, Jerry Slootstra, Rob H. Meloen, Willem Hendrik H. Gispen, J. Peter H. Burbach, and Roger A. H. Adan

Conformation of the Core Sequence in Melanocortin Peptides Directs Selectivity for the Melanocortin MC3 and MC4 Receptors
1999 274: 16853-16860. [Abstract] [Full Text] [PDF]

Wulf Dirk Leuschner and Werner Hoch

Subtype-specific Assembly of -Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunits Is Mediated by Their N-terminal Domains
1999 274: 16907-16916. [Abstract] [Full Text] [PDF]

Czeslaw S. Cierniewski, Tatiana Byzova, Malgorzata Papierak, Thomas A. Haas, Jolanta Niewiarowska, Li Zhang, Marcin Cieslak, and Edward F. Plow

Peptide Ligands Can Bind to Distinct Sites in Integrin _IIb3 and Elicit Different Functional Responses
1999 274: 16923-16932. [Abstract] [Full Text] [PDF]

Jin-Yu Liu, Tao Jiang, Ji-Ping Zhang, and Dong-Cai Liang

Crystal Structure of Allophycocyanin from Red Algae Porphyra yezoensis at 2.2-Å Resolution
1999 274: 16945-16952. [Abstract] [Full Text] [PDF]

Claus Oxvig, Anni R. Thomsen, Michael T. Overgaard, Esben S. Sørensen, Peter Højrup, Morten J. Bjerrum, Gerald J. Gleich, and Lars Sottrup-Jensen

Biochemical Evidence for Heme Linkage through Esters with Asp-93 and Glu-241 in Human Eosinophil Peroxidase. THE ESTER WITH ASP-93 IS ONLY PARTIALLY FORMED IN VIVO
1999 274: 16953-16958. [Abstract] [Full Text] [PDF]

Qin Liu, Changwen Jin, Xiubei Liao, Zhiyuan Shen, David J. Chen, and Yuan Chen

The Binding Interface between an E2 (UBC9) and a Ubiquitin Homologue (UBL1)
1999 274: 16979-16987. [Abstract] [Full Text] [PDF]

Julie L. Wilsbacher, Elizabeth J. Goldsmith, and Melanie H. Cobb

Phosphorylation of MAP Kinases by MAP/ERK Involves Multiple Regions of MAP Kinases
1999 274: 16988-16994. [Abstract] [Full Text] [PDF]

Søren P. Sheikh, Jean-Pierre Vilardarga, Thomas J. Baranski, Olivier Lichtarge, Taroh Iiri, Elaine C. Meng, Robert A. Nissenson, and Henry R. Bourne

Similar Structures and Shared Switch Mechanisms of the ₂-Adrenoceptor and the Parathyroid Hormone Receptor. Zn(II) BRIDGES BETWEEN HELICES III AND VI BLOCK ACTIVATION
1999 274: 17033-17041. [Abstract] [Full Text] [PDF]

Isabel Pérez-Mato, Carmen Castro, Félix A. Ruiz, Fernando J. Corrales, and José M. Mato

Methionine Adenosyltransferase S-Nitrosylation Is Regulated by the Basic and Acidic Amino Acids Surrounding the Target Thiol
1999 274: 17075-17079. [Abstract] [Full Text] [PDF]

Caroline Jill Rieke, Anne M. Mulichak, R. Michael Garavito, and William L. Smith

The Role of Arginine 120 of Human Prostaglandin Endoperoxide H Synthase-2 in the Interaction with Fatty Acid Substrates and Inhibitors
1999 274: 17109-17114. [Abstract] [Full Text] [PDF]

Xavier Espanel and Marius Sudol

A Single Point Mutation in a Group I WW Domain Shifts Its Specificity to That of Group II WW Domains
1999 274: 17284-17289. [Abstract] [Full Text] [PDF]

Additions and Corrections

Kenji E. Orii, Koji O. Orii, Masayoshi Souri, Tadao Orii, Naomi Kondo, Takashi Hashimoto, and Toshifumi Aoyama

Additions and Corrections to Genes for the human mitochondrial trifunctional protein - and -subunits are divergently transcribed from a common promoter region.
1999 274: 17394. [Full Text] [PDF]

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