Minireviews

Xiaoming Zou and Kathryn Calame

Signaling Pathways Activated by Oncogenic Forms of Abl Tyrosine Kinase
1999 274: 18141-18144. [Full Text] [PDF]

Communications

Andrew P. Kowalczyk, Mechthild Hatzfeld, Elayne A. Bornslaeger, Daniel S. Kopp, Jeffrey E. Borgwardt, Connie M. Corcoran, Aaron Settler, and Kathleen J. Green

The Head Domain of Plakophilin-1 Binds to Desmoplakin and Enhances Its Recruitment to Desmosomes. IMPLICATIONS FOR CUTANEOUS DISEASE
1999 274: 18145-18148. [Abstract] [Full Text] [PDF]

Ulrike Zabel, Christoph Häusler, Monika Weeger, and Harald H. H. W. Schmidt

Homodimerization of Soluble Guanylyl Cyclase Subunits. DIMERIZATION ANALYSIS USING A GLUTATHIONE S-TRANSFERASE AFFINITY TAG
1999 274: 18149-18152. [Abstract] [Full Text] [PDF]

Heike Zitzer, Dietmar Richter, and Hans-Jürgen Kreienkamp

Agonist-dependent Interaction of the Rat Somatostatin Receptor Subtype 2 with Cortactin-binding Protein 1
1999 274: 18153-18156. [Abstract] [Full Text] [PDF]

Kirk G. Tanner, Raymond C. Trievel, Min-Hao Kuo, Robyn M. Howard, Shelley L. Berger, C. David Allis, Ronen Marmorstein, and John M. Denu

Catalytic Mechanism and Function of Invariant Glutamic Acid 173 from the Histone Acetyltransferase GCN5 Transcriptional Coactivator
1999 274: 18157-18160. [Abstract] [Full Text] [PDF]

Philipp O. Tsvetkov, Irina I. Protasevich, Robert Gilli, Daniel Lafitte, Vladimir M. Lobachov, Jacques Haiech, Claudette Briand, and Alexander A. Makarov

Apocalmodulin Binds to the Myosin Light Chain Kinase Calmodulin Target Site
1999 274: 18161-18164. [Abstract] [Full Text] [PDF]

Carbohydrates, Lipids, and Other Natural Products

Stefan Müller, Kim Alving, Jasna Peter-Katalinic, Natasha Zachara, Andrew A. Gooley, and Franz-Georg Hanisch

High Density O-Glycosylation on Tandem Repeat Peptide from Secretory MUC1 of T47D Breast Cancer Cells
1999 274: 18165-18172. [Abstract] [Full Text] [PDF]

Chih-Fang Chao, Han-Chang Chuang, Shean-Tai Chiou, and Teh-Yung Liu

On the Biosynthesis of Alternating -2,9/-2,8 Heteropolymer of Sialic Acid Catalyzed by the Sialyltransferase of Escherichia coli Bos-12
1999 274: 18206-18212. [Abstract] [Full Text] [PDF]

Christine Galustian, André Lubineau, Christine le Narvor, Makoto Kiso, Gavin Brown, and Ten Feizi

L-selectin Interactions with Novel Mono- and Multisulfated Lewis^x Sequences in Comparison with the Potent Ligand 3'-Sulfated Lewis^a
1999 274: 18213-18217. [Abstract] [Full Text] [PDF]

Catherine L. R. Merry, Malcolm Lyon, Jon A. Deakin, John J. Hopwood, and John T. Gallagher

Highly Sensitive Sequencing of the Sulfated Domains of Heparan Sulfate
1999 274: 18455-18462. [Abstract] [Full Text] [PDF]

Tomoko Oya, Nobutaka Hattori, Yoshikuni Mizuno, Satoshi Miyata, Sakan Maeda, Toshihiko Osawa, and Koji Uchida

Methylglyoxal Modification of Protein. CHEMICAL AND IMMUNOCHEMICAL CHARACTERIZATION OF METHYLGLYOXAL-ARGININE ADDUCTS
1999 274: 18492-18502. [Abstract] [Full Text] [PDF]

Zhimin Zhou, Shanhua Lin, Robert J. Cotter, and Christian R. H. Raetz

Lipid A Modifications Characteristic of Salmonella typhimurium Are Induced by NH₄VO₃ in Escherichia coli K12. DETECTION OF 4-AMINO-4-DEOXY-L-ARABINOSE, PHOSPHOETHANOLAMINE AND PALMITATE
1999 274: 18503-18514. [Abstract] [Full Text] [PDF]

Yeongjin Hong, Kazuhito Ohishi, Reika Watanabe, Yuichi Endo, Yusuke Maeda, and Taroh Kinoshita

GPI1 Stabilizes an Enzyme Essential in the First Step of Glycosylphosphatidylinositol Biosynthesis
1999 274: 18582-18588. [Abstract] [Full Text] [PDF]

Manuel Romarís, Christien Coomans, Helga Ceulemans, Anne-Mie Bruystens, Sylvie Vekemans, and Guido David

Molecular Polymorphism of the Syndecans. IDENTIFICATION OF A HYPO-GLYCANATED MURINE SYNDECAN-1 SPLICE VARIANT
1999 274: 18667-18674. [Abstract] [Full Text] [PDF]

Cell Biology and Metabolism

Vanessa Van Harmelen, Signy Reynisdottir, Katherine Cianflone, Eva Degerman, Johan Hoffstedt, Klas Nilsell, Allan Sniderman, and Peter Arner

Mechanisms Involved in the Regulation of Free Fatty Acid Release from Isolated Human Fat Cells by Acylation-stimulating Protein and Insulin
1999 274: 18243-18251. [Abstract] [Full Text] [PDF]

Stefan Butz, Rafael Fernandez-Chacon, Frank Schmitz, Reinhard Jahn, and Thomas C. Südhof

The Subcellular Localizations of Atypical Synaptotagmins III and VI. SYNAPTOTAGMIN III IS ENRICHED IN SYNAPSES AND SYNAPTIC PLASMA MEMBRANES BUT NOT IN SYNAPTIC VESICLES
1999 274: 18290-18296. [Abstract] [Full Text] [PDF]

Eleonora Palma, Laura Maggi, Benedetta Barabino, Fabrizio Eusebi, and Marco Ballivet

Nicotinic Acetylcholine Receptors Assembled from the 7 and 3 Subunits
1999 274: 18335-18340. [Abstract] [Full Text] [PDF]

Russell A. Wilke, Rakesh P. Mehta, Patrick J. Lupardus, Yuenmu Chen, Arnold E. Ruoho, and Meyer B. Jackson

Sigma Receptor Photolabeling and Sigma Receptor-mediated Modulation of Potassium Channels in Tumor Cells
1999 274: 18387-18392. [Abstract] [Full Text] [PDF]

Kuang-Den Chen, Yi-Shuan Li, Michael Kim, Song Li, Suli Yuan, Shu Chien, and John Y-J. Shyy

Mechanotransduction in Response to Shear Stress. ROLES OF RECEPTOR TYROSINE KINASES, INTEGRINS, AND Shc
1999 274: 18393-18400. [Abstract] [Full Text] [PDF]

David R. Jones, Ana González-García, Emilio Díez, Carlos Martinez-A., Ana C. Carrera, and Isabel Mérida

The Identification of Phosphatidylinositol 3,5-bisphosphate in T-lymphocytes and Its Regulation by Interleukin-2
1999 274: 18407-18413. [Abstract] [Full Text] [PDF]

Paul A. Steimle, Jason D. Hoffert, Nils B. Adey, and Susan W. Craig

Polyphosphoinositides Inhibit the Interaction of Vinculin with Actin Filaments
1999 274: 18414-18420. [Abstract] [Full Text] [PDF]

Sonia A. Cunningham, Tuan M. Tran, M. Pia Arrate, and Tommy A. Brock

Characterization of Vascular Endothelial Cell Growth Factor Interactions with the Kinase Insert Domain-containing Receptor Tyrosine Kinase. A REAL TIME KINETIC STUDY
1999 274: 18421-18427. [Abstract] [Full Text] [PDF]

Heike Allgayer, Heng Wang, Gary E. Gallick, Andrea Crabtree, Andrew Mazar, Terence Jones, Alan J. Kraker, and Douglas D. Boyd

Transcriptional Induction of the Urokinase Receptor Gene by a Constitutively Active Src. REQUIREMENT OF AN UPSTREAM MOTIF (152/135) BOUND WITH Sp1
1999 274: 18428-18437. [Abstract] [Full Text] [PDF]

Masaya Okamoto, Susanne Schoch, and Thomas C. Südhof

EHSH1/Intersectin, a Protein That Contains EH and SH3 Domains and Binds to Dynamin and SNAP-25. A PROTEIN CONNECTION BETWEEN EXOCYTOSIS AND ENDOCYTOSIS?
1999 274: 18446-18454. [Abstract] [Full Text] [PDF]

Noriyuki Tsukamoto, Masakazu Hattori, Hailin Yang, Johannes L. Bos, and Nagahiro Minato

Rap1 GTPase-activating Protein SPA-1 Negatively Regulates Cell Adhesion
1999 274: 18463-18469. [Abstract] [Full Text] [PDF]

Mathias Rouard, Joseph Bass, Florin Grigorescu, Thomas P. J. Garrett, Colin W. Ward, Gregory Lipkind, Claude Jaffiole, Donald F. Steiner, and Graeme I. Bell

Congenital Insulin Resistance Associated with a Conformational Alteration in a Conserved -Sheet in the Insulin Receptor L1 Domain
1999 274: 18487-18491. [Abstract] [Full Text] [PDF]

Olivier Déry, Mark S. Thoma, Helen Wong, Eileen F. Grady, and Nigel W. Bunnett

Trafficking of Proteinase-activated Receptor-2 and -Arrestin-1 Tagged with Green Fluorescent Protein. -ARRESTIN-DEPENDENT ENDOCYTOSIS OF A PROTEINASE RECEPTOR
1999 274: 18524-18535. [Abstract] [Full Text] [PDF]

Bryan W. Johnson and Lawrence H. Boise

Bcl-2 and Caspase Inhibition Cooperate to Inhibit Tumor Necrosis Factor--induced Cell Death in a Bcl-2 Cleavage-independent Fashion
1999 274: 18552-18558. [Abstract] [Full Text] [PDF]

Mark H. C. Lam, Colin M. House, Tony Tiganis, Ken I. Mitchelhill, Boris Sarcevic, Alina Cures, Robert Ramsay, Bruce E. Kemp, T. John Martin, and Matthew T. Gillespie

Phosphorylation at the Cyclin-dependent Kinases Site (Thr⁸⁵) of Parathyroid Hormone-related Protein Negatively Regulates Its Nuclear Localization
1999 274: 18559-18566. [Abstract] [Full Text] [PDF]

Toshiro Mikami, Takehiro Kusakabe, and Norio Suzuki

Tandem Organization of Medaka Fish Soluble Guanylyl Cyclase ₁ and ₁ Subunit Genes. IMPLICATIONS FOR COORDINATED TRANSCRIPTION OF TWO SUBUNIT GENES
1999 274: 18567-18573. [Abstract] [Full Text] [PDF]

Richard L. Goodwin, Lil M. Pabón-Peña, Gayle C. Foster, and David Bader

The Cloning and Analysis of LEK1 Identifies Variations in the LEK/Centromere Protein F/Mitosin Gene Family
1999 274: 18597-18604. [Abstract] [Full Text] [PDF]

Elisabetta Meacci, Valeria Vasta, Jonathan P. Moorman, David A. Bobak, Paola Bruni, Joel Moss, and Martha Vaughan

Effect of Rho and ADP-ribosylation Factor GTPases on Phospholipase D Activity in Intact Human Adenocarcinoma A549 Cells
1999 274: 18605-18612. [Abstract] [Full Text] [PDF]

Raymond V. Fucini, Shuichi Okada, and Jeffrey E. Pessin

Insulin-induced Desensitization of Extracellular Signal-regulated Kinase Activation Results from an Inhibition of Raf Activity Independent of Ras Activation and Dissociation of the Grb2-SOS Complex
1999 274: 18651-18658. [Abstract] [Full Text] [PDF]

Toshihiro Mochizuki, Chifumi Kitanaka, Kohji Noguchi, Tomonari Muramatsu, Akio Asai, and Yoshiyuki Kuchino

Physical and Functional Interactions between Pim-1 Kinase and Cdc25A Phosphatase. IMPLICATIONS FOR THE Pim-1-MEDIATED ACTIVATION OF THE c-Myc SIGNALING PATHWAY
1999 274: 18659-18666. [Abstract] [Full Text] [PDF]

Derek Strassheim, Lisa G. May, Kimberly A. Varker, Henry L. Puhl, Scott H. Phelps, Rebecca A. Porter, Robert S. Aronstam, John D. Noti, and Carol L. Williams

M₃ Muscarinic Acetylcholine Receptors Regulate Cytoplasmic Myosin by a Process Involving RhoA and Requiring Conventional Protein Kinase C Isoforms
1999 274: 18675-18685. [Abstract] [Full Text] [PDF]

Guim Kwon, Guang Xu, Connie A. Marshall, and Michael L. McDaniel

Tumor Necrosis Factor -induced Pancreatic -Cell Insulin Resistance Is Mediated by Nitric Oxide and Prevented by 15-Deoxy-^12,14-prostaglandin J₂ and Aminoguanidine. A ROLE FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR  ACTIVATION AND iNOS EXPRESSION
1999 274: 18702-18708. [Abstract] [Full Text] [PDF]

Chang Y. Guo, Yu Wang, David L. Brautigan, and James M. Larner

Histone H1 Dephosphorylation Is Mediated through a Radiation-induced Signal Transduction Pathway Dependent on ATM
1999 274: 18715-18720. [Abstract] [Full Text] [PDF]

Kallol Das, Renée Y. Lewis, Philipp E. Scherer, and Michael P. Lisanti

The Membrane-spanning Domains of Caveolins-1 and -2 Mediate the Formation of Caveolin Hetero-oligomers. IMPLICATIONS FOR THE ASSEMBLY OF CAVEOLAE MEMBRANES IN VIVO
1999 274: 18721-18728. [Abstract] [Full Text] [PDF]

Li-Yun Tsai, Shuh-Long Tu, and Hsou-min Li

Insertion of atToc34 into the Chloroplastic Outer Membrane Is Assisted by at Least Two Proteinaceous Components in the Import System
1999 274: 18735-18740. [Abstract] [Full Text] [PDF]

Jürgen Stolz, Ursula Hoja, Sandra Meier, Norbert Sauer, and Eckhart Schweizer

Identification of the Plasma Membrane H⁺-Biotin Symporter of Saccharomyces cerevisiae by Rescue of a Fatty Acid-auxotrophic Mutant
1999 274: 18741-18746. [Abstract] [Full Text] [PDF]

Jürgen Stolz and Norbert Sauer

The Fenpropimorph Resistance Gene FEN2 from Saccharomyces cerevisiae Encodes a Plasma Membrane H⁺-Pantothenate Symporter
1999 274: 18747-18752. [Abstract] [Full Text] [PDF]

Joy Yohannan, Jürgen Wienands, K. Mark Coggeshall, and Louis B. Justement

Analysis of Tyrosine Phosphorylation-dependent Interactions between Stimulatory Effector Proteins and the B Cell Co-receptor CD22
1999 274: 18769-18776. [Abstract] [Full Text] [PDF]

Rina Yamin, Eric G. Malgeri, Jacob A. Sloane, Walker T. McGraw, and Carmela R. Abraham

Metalloendopeptidase EC 3.4.24.15 Is Necessary for Alzheimer's Amyloid- Peptide Degradation
1999 274: 18777-18784. [Abstract] [Full Text] [PDF]

Sushant Kumar, Andrea L. Talis, and Peter M. Howley

Identification of HHR23A as a Substrate for E6-associated Protein-mediated Ubiquitination
1999 274: 18785-18792. [Abstract] [Full Text] [PDF]

C. Simone Fishburn, Paul Herzmark, Janine Morales, and Henry R. Bourne

G and Palmitate Target Newly Synthesized G_z to the Plasma Membrane
1999 274: 18793-18800. [Abstract] [Full Text] [PDF]

Thomas R. Newton, Nikhil M. Patel, Poornima Bhat-Nakshatri, Carmen R. Stauss, Robert J. Goulet Jr., and Harikrishna Nakshatri

Negative Regulation of Transactivation Function but Not DNA Binding of NF-B and AP-1 by IB1 in Breast Cancer Cells
1999 274: 18827-18835. [Abstract] [Full Text] [PDF]

Kirk M. Druey, Ozlem Ugur, Joan M. Caron, Ching-Kang Chen, Peter S. Backlund, and Teresa L. Z. Jones

Amino-terminal Cysteine Residues of RGS16 Are Required for Palmitoylation and Modulation of G_i- and G_q-mediated Signaling
1999 274: 18836-18842. [Abstract] [Full Text] [PDF]

Enzymology

Hiroshi Sakamoto, Yoshiaki Omata, Graham Palmer, and Masato Noguchi

Ferric -Hydroxyheme Bound to Heme Oxygenase Can Be Converted to Verdoheme by Dioxygen in the Absence of Added Reducing Equivalents
1999 274: 18196-18200. [Abstract] [Full Text] [PDF]

Katsuyoshi Fujikawa, Hiroyuki Kamiya, Hiroyuki Yakushiji, Yoshimitsu Fujii, Yusaku Nakabeppu, and Hiroshi Kasai

The Oxidized Forms of dATP Are Substrates for the Human MutT Homologue, the hMTH1 Protein
1999 274: 18201-18205. [Abstract] [Full Text] [PDF]

Vincent Nivière, Franck Fieschi, Jean-Luc Décout, and Marc Fontecave

The NAD(P)H:Flavin Oxidoreductase from Escherichia coli. EVIDENCE FOR A NEW MODE OF BINDING FOR REDUCED PYRIDINE NUCLEOTIDES
1999 274: 18252-18260. [Abstract] [Full Text] [PDF]

Kotomi Fujishige, Jun Kotera, Hideo Michibata, Keizo Yuasa, Shin-ichiro Takebayashi, Katsuzumi Okumura, and Kenji Omori

Cloning and Characterization of a Novel Human Phosphodiesterase That Hydrolyzes Both cAMP and cGMP (PDE10A)
1999 274: 18438-18445. [Abstract] [Full Text] [PDF]

Masamichi Muramatsu, V. S. Sankaranand, Shrikant Anant, Manabu Sugai, Kazuo Kinoshita, Nicholas O. Davidson, and Tasuku Honjo

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells
1999 274: 18470-18476. [Abstract] [Full Text] [PDF]

Hongmei Mou, Hector J. Grazio III, Terry A. Cook, Joseph A. Beavo, and Rick H. Cote

cGMP Binding to Noncatalytic Sites on Mammalian Rod Photoreceptor Phosphodiesterase Is Regulated by Binding of Its  and  Subunits
1999 274: 18813-18820. [Abstract] [Full Text] [PDF]

Kouji Kuno, Yuya Terashima, and Kouji Matsushima

ADAMTS-1 Is an Active Metalloproteinase Associated with the Extracellular Matrix
1999 274: 18821-18826. [Abstract] [Full Text] [PDF]

Membranes and Bioenergetics

Pei-Qi Liu, Cheng E. Liu, and Giovanna Ferro-Luzzi Ames

Modulation of ATPase Activity by Physical Disengagement of the ATP-binding Domains of an ABC Transporter, the Histidine Permease
1999 274: 18310-18318. [Abstract] [Full Text] [PDF]

Yu Chen, Melvin Schindler, and Sanford M. Simon

A Mechanism for Tamoxifen-mediated Inhibition of Acidification
1999 274: 18364-18373. [Abstract] [Full Text] [PDF]

Rhoda Blostein, Lisa Dunbar, Martin Mense, Rosemarie Scanzano, Ania Wilczynska, and Michael J. Caplan

Cation Selectivity of Gastric H,K-ATPase and Na,K-ATPase Chimeras
1999 274: 18374-18381. [Abstract] [Full Text] [PDF]

R. Preston Mason, Robert F. Jacob, Mary F. Walter, Pamela E. Mason, Nicolai A. Avdulov, Svetlana V. Chochina, Urule Igbavboa, and W. Gibson Wood

Distribution and Fluidizing Action of Soluble and Aggregated Amyloid -Peptide in Rat Synaptic Plasma Membranes
1999 274: 18801-18807. [Abstract] [Full Text] [PDF]

Derek W. Abbott, Marilyn E. Thompson, Cheryl Robinson-Benion, Gail Tomlinson, Roy A. Jensen, and Jeffrey T. Holt

BRCA1 Expression Restores Radiation Resistance in BRCA1-defective Cancer Cells through Enhancement of Transcription-coupled DNA Repair
1999 274: 18808-18812. [Abstract] [Full Text] [PDF]

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Catalina Hernández-Sánchez, Yutaka Ito, Jorge Ferrer, Marc Reitman, and Derek LeRoith

Characterization of the Mouse Sulfonylurea Receptor 1 Promoter and Its Regulation
1999 274: 18261-18270. [Abstract] [Full Text] [PDF]

Richard A. Rachubinski, Sandra L. Marcus, and John P. Capone

The p56^lck-interacting Protein p62 Stimulates Transcription via the SV40 Enhancer
1999 274: 18278-18284. [Abstract] [Full Text] [PDF]

Marjorie Brand, Ken Yamamoto, Adrien Staub, and Laszlo Tora

Identification of TATA-binding Protein-free TAF_II-containing Complex Subunits Suggests a Role in Nucleosome Acetylation and Signal Transduction
1999 274: 18285-18289. [Abstract] [Full Text] [PDF]

Eriko Matsui, Satoko Kawasaki, Hiroyasu Ishida, Kazuhiko Ishikawa, Yoshitugu Kosugi, Hisashi Kikuchi, Yutaka Kawarabayashi, and Ikuo Matsui

Thermostable Flap Endonuclease from the Archaeon, Pyrococcus horikoshii, Cleaves the Replication Fork-like Structure Endo/Exonucleolytically
1999 274: 18297-18309. [Abstract] [Full Text] [PDF]

Lynda T. Lucas, David Gatehouse, and David E. G. Shuker

Efficient Nitroso Group Transfer from N-Nitrosoindoles to Nucleotides and 2'-Deoxyguanosine at Physiological pH. A NEW PATHWAY FOR N-NITROSOCOMPOUNDS TO EXERT GENOTOXICITY
1999 274: 18319-18326. [Abstract] [Full Text] [PDF]

Jack D. Kelly, Alberto Inga, Fa-Xian Chen, Prasad Dande, Dharini Shah, Paola Monti, Anna Aprile, Philip A. Burns, Gina Scott, Angelo Abbondandolo, Barry Gold, and Gilberto Fronza

Relationship between DNA Methylation and Mutational Patterns Induced by a Sequence Selective Minor Groove Methylating Agent
1999 274: 18327-18334. [Abstract] [Full Text] [PDF]

Robert M. Brosh Jr., David K. Orren, Jan O. Nehlin, Peter H. Ravn, Mark K. Kenny, Amrita Machwe, and Vilhelm A. Bohr

Functional and Physical Interaction between WRN Helicase and Human Replication Protein A
1999 274: 18341-18350. [Abstract] [Full Text] [PDF]

Yong Liu, Ronald B. Emeson, and Charles E. Samuel

Serotonin-2C Receptor Pre-mRNA Editing in Rat Brain and in Vitro by Splice Site Variants of the Interferon-inducible Double-stranded RNA-specific Adenosine Deaminase ADAR1
1999 274: 18351-18358. [Abstract] [Full Text] [PDF]

Azra Rabbani, Maya Iskandar, and Juan Ausió

Daunomycin-induced Unfolding and Aggregation of Chromatin
1999 274: 18401-18406. [Abstract] [Full Text] [PDF]

Sam S. K. Lee and I. R. Lehman

The Interaction of Herpes Simplex Type 1 Virus Origin-binding Protein (UL9 Protein) with Box I, the High Affinity Element of the Viral Origin of DNA Replication
1999 274: 18613-18617. [Abstract] [Full Text] [PDF]

Stacey C. Chapman, Julio E. Ayala, Ryan S. Streeper, Ainsley A. Culbert, Erin M. Eaton, Christina A. Svitek, Joshua K. Goldman, Jeremy M. Tavaré, and Richard M. O'Brien

Multiple Promoter Elements Are Required for the Stimulatory Effect of Insulin on Human Collagenase-1 Gene Transcription. SELECTIVE EFFECTS ON ACTIVATOR PROTEIN-1 EXPRESSION MAY EXPLAIN THE QUANTITATIVE DIFFERENCE IN INSULIN AND PHORBOL ESTER ACTION
1999 274: 18625-18634. [Abstract] [Full Text] [PDF]

Steven A. Enkemann, Karen S. Pavur, Alexey G. Ryazanov, and Shelby L. Berger

Does Prothymosin  Affect the Phosphorylation of Elongation Factor 2?
1999 274: 18644-18650. [Abstract] [Full Text] [PDF]

Elisabeth D. Galsgaard, Jens H. Nielsen, and Annette Møldrup

Regulation of Prolactin Receptor (PRLR) Gene Expression in Insulin-producing Cells. PROLACTIN AND GROWTH HORMONE ACTIVATE ONE OF THE RAT PRLR GENE PROMOTERS VIA STAT5a AND STAT5b
1999 274: 18686-18692. [Abstract] [Full Text] [PDF]

Elena S. Tasheva, Martha L. Funderburgh, James McReynolds, James L. Funderburgh, and Gary W. Conrad

The Bovine Mimecan Gene. MOLECULAR CLONING AND CHARACTERIZATION OF TWO MAJOR RNA TRANSCRIPTS GENERATED BY ALTERNATIVE USE OF TWO SPLICE ACCEPTOR SITES IN THE THIRD EXON
1999 274: 18693-18701. [Abstract] [Full Text] [PDF]

Xuan Zhou, Sang Ick Park, Mohamed E. Moustafa, Bradley A. Carlson, Pamela F. Crain, Alan M. Diamond, Dolph L. Hatfield, and Byeong Jae Lee

Selenium Metabolism in Drosophila. CHARACTERIZATION OF THE SELENOCYSTEINE tRNA POPULATION
1999 274: 18729-18734. [Abstract] [Full Text] [PDF]

Jacob Falck, Peter B. Jensen, and Maxwell Sehested

Evidence for Repressional Role of an Inverted CCAAT Box in Cell Cycle-dependent Transcription of the Human DNA Topoisomerase II Gene
1999 274: 18753-18758. [Abstract] [Full Text] [PDF]

Mitsuo Wakasugi and Aziz Sancar

Order of Assembly of Human DNA Repair Excision Nuclease
1999 274: 18759-18768. [Abstract] [Full Text] [PDF]

Protein Chemistry and Structure

Tetsuo Yamazaki, Yuki Hamano, Hironori Tashiro, Katsuhiko Itoh, Hiroyasu Nakano, Shoichiro Miyatake, and Takashi Saito

CAST, a Novel CD3-binding Protein Transducing Activation Signal for Interleukin-2 Production in T Cells
1999 274: 18173-18180. [Abstract] [Full Text] [PDF]

Jochen Kruip, Navassard V. Karapetyan, Irina V. Terekhova, and Matthias Rögner

In Vitro Oligomerization of a Membrane Protein Complex. LIPOSOME-BASED RECONSTITUTION OF TRIMERIC PHOTOSYSTEM I FROM ISOLATED MONOMERS
1999 274: 18181-18188. [Abstract] [Full Text] [PDF]

Carlos Henrique I. Ramos

Mapping Subdomains in the C-terminal Region of Troponin I Involved in Its Binding to Troponin C and to Thin Filament
1999 274: 18189-18195. [Abstract] [Full Text] [PDF]

Hans J. de Haard, Nicole van Neer, Anneke Reurs, Simon E. Hufton, Rob C. Roovers, Paula Henderikx, Adriaan P. de Bruïne, Jan-Willem Arends, and Hennie R. Hoogenboom

A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies
1999 274: 18218-18230. [Abstract] [Full Text] [PDF]

Chen-Yong Lin, Joanna Anders, Michael Johnson, Qingxiang Amy Sang, and Robert B. Dickson

Molecular Cloning of cDNA for Matriptase, a Matrix-degrading Serine Protease with Trypsin-like Activity
1999 274: 18231-18236. [Abstract] [Full Text] [PDF]

Chen-Yong Lin, Joanna Anders, Michael Johnson, and Robert B. Dickson

Purification and Characterization of a Complex Containing Matriptase and a Kunitz-type Serine Protease Inhibitor from Human Milk
1999 274: 18237-18242. [Abstract] [Full Text] [PDF]

David J. Timson, Hylary R. Trayer, K. John Smith, and Ian P. Trayer

Size and Charge Requirements for Kinetic Modulation and Actin Binding by Alkali 1-type Myosin Essential Light Chains
1999 274: 18271-18277. [Abstract] [Full Text] [PDF]

Thomas C. Evans Jr., Jack Benner, and Ming-Qun Xu

The Cyclization and Polymerization of Bacterially Expressed Proteins Using Modified Self-splicing Inteins
1999 274: 18359-18363. [Abstract] [Full Text] [PDF]

Hans Bräuner-Osborne, Anders A. Jensen, Paul O. Sheppard, Patrick O'Hara, and Povl Krogsgaard-Larsen

The Agonist-binding Domain of the Calcium-sensing Receptor Is Located at the Amino-terminal Domain
1999 274: 18382-18386. [Abstract] [Full Text] [PDF]

Akash Mathur and S. Paul Bajaj

Protease and EGF1 Domains of Factor IXa Play Distinct Roles in Binding to Factor VIIIa. IMPORTANCE OF HELIX 330 (HELIX 162 IN CHYMOTRYPSIN) OF PROTEASE DOMAIN OF FACTOR IXa IN ITS INTERACTION WITH FACTOR VIIIa
1999 274: 18477-18486. [Abstract] [Full Text] [PDF]

Ulrika Lind, Paulette Greenidge, Jan-Åke Gustafsson, Anthony P. H. Wright, and Jan Carlstedt-Duke

Valine 571 Functions as a Regional Organizer in Programming the Glucocorticoid Receptor for Differential Binding of Glucocorticoids and Mineralocorticoids
1999 274: 18515-18523. [Abstract] [Full Text] [PDF]

Yukiko Shimada, Megumi Nakamura, Yasuhide Naito, Kohji Nomura, and Yoshiko Ohno-Iwashita

C-terminal Amino Acid Residues Are Required for the Folding and Cholesterol Binding Property of Perfringolysin O, a Pore-forming Cytolysin
1999 274: 18536-18542. [Abstract] [Full Text] [PDF]

Bo Jiang and Martha S. Cyert

Identification of a Novel Region Critical for Calcineurin Function in Vivo and in Vitro
1999 274: 18543-18551. [Abstract] [Full Text] [PDF]

Katia Befort, Christelle Zilliox, Dominique Filliol, ShiYi Yue, and Brigitte L. Kieffer

Constitutive Activation of the  Opioid Receptor by Mutations in Transmembrane Domains III and VII
1999 274: 18574-18581. [Abstract] [Full Text] [PDF]

Benjamin Schuler, Reinhard Rachel, and Robert Seckler

Formation of Fibrous Aggregates from a Non-native Intermediate: The Isolated P22 Tailspike -Helix Domain
1999 274: 18589-18596. [Abstract] [Full Text] [PDF]

Steven R. LaPlante, Dale R. Cameron, Norman Aubry, Sylvain Lefebvre, George Kukolj, Roger Maurice, Diane Thibeault, Daniel Lamarre, and Montse Llinàs-Brunet

Solution Structure of Substrate-based Ligands When Bound to Hepatitis C Virus NS3 Protease Domain
1999 274: 18618-18624. [Abstract] [Full Text] [PDF]

Kumudini R. Dharmawardana, Steven T. Olson, and Paul E. Bock

Role of Regulatory Exosite I in Binding of Thrombin to Human Factor V, Factor Va, Factor Va Subunits, and Activation Fragments
1999 274: 18635-18643. [Abstract] [Full Text] [PDF]

Timothy S. Davison, Christine Vagner, Mourad Kaghad, Ayeda Ayed, Daniel Caput, and Cheryl H. Arrowsmith

p73 and p63 Are Homotetramers Capable of Weak Heterotypic Interactions with Each Other but Not with p53
1999 274: 18709-18714. [Abstract] [Full Text] [PDF]

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