Minireviews

Hideaki Nagase and J. Frederick Woessner Jr.

Matrix Metalloproteinases
J. Biol. Chem. 1999 274: 21491-21494. [Full Text] [PDF]  

Communications

Ruping Shao, Mickey C.-T. Hu, Binhua P. Zhou, Shiaw-Yih Lin, Paul J. Chiao, Ryan H. von Lindern, Bill Spohn, and Mien-Chie Hung

E1A Sensitizes Cells to Tumor Necrosis Factor-induced Apoptosis through Inhibition of IB Kinases and Nuclear Factor B Activities
J. Biol. Chem. 1999 274: 21495-21498. [Abstract] [Full Text] [PDF]  

Hans-Jürgen Mägert, Ludger Ständker, Peter Kreutzmann, Hans-Dieter Zucht, Manfred Reinecke, Christian Peter Sommerhoff, Hans Fritz, and Wolf-Georg Forssmann

LEKTI, a Novel 15-Domain Type of Human Serine Proteinase Inhibitor
J. Biol. Chem. 1999 274: 21499-21502. [Abstract] [Full Text] [PDF]  

James N. Muth, Hiroshi Yamaguchi, Gabor Mikala, Ingrid L. Grupp, William Lewis, Heping Cheng, Long-Sheng Song, Edward G. Lakatta, Gyula Varadi, and Arnold Schwartz

Cardiac-specific Overexpression of the ₁ Subunit of the L-type Voltage-dependent Ca²⁺ Channel in Transgenic Mice. LOSS OF ISOPROTERENOL-INDUCED CONTRACTION
J. Biol. Chem. 1999 274: 21503-21506. [Abstract] [Full Text] [PDF]  

J. Dedrick Jordan, Kendall D. Carey, Philip J. S. Stork, and Ravi Iyengar

Modulation of Rap Activity by Direct Interaction of G_o with Rap1 GTPase-activating Protein
J. Biol. Chem. 1999 274: 21507-21510. [Abstract] [Full Text] [PDF]  

Wallace L. McKeehan, Xiaochong Wu, and Mikio Kan

Requirement for Anticoagulant Heparan Sulfate in the Fibroblast Growth Factor Receptor Complex
J. Biol. Chem. 1999 274: 21511-21514. [Abstract] [Full Text] [PDF]  

Michael H. Hu, Eve Marie Bauman, Richard L. Roll, Newman Yeilding, and Charles S. Abrams

Pleckstrin 2, a Widely Expressed Paralog of Pleckstrin Involved in Actin Rearrangement
J. Biol. Chem. 1999 274: 21515-21518. [Abstract] [Full Text] [PDF]  

Carbohydrates, Lipids, and Other Natural Products

Keith Watson, Nigel J. Gooderham, Donald S. Davies, and Robert J. Edwards

Nucleosomes Bind to Cell Surface Proteoglycans
J. Biol. Chem. 1999 274: 21707-21713. [Abstract] [Full Text] [PDF]  

Haralt Leiter, Jan Mucha, Erika Staudacher, Rudolf Grimm, Josef Glössl, and Friedrich Altmann

Purification, cDNA Cloning, and Expression of GDP-L-Fuc:Asn-linked GlcNAc 1,3-Fucosyltransferase from Mung Beans
J. Biol. Chem. 1999 274: 21830-21839. [Abstract] [Full Text] [PDF]  

Cell Biology and Metabolism

Sigal Gelkop and Noah Isakov

T Cell Activation Stimulates the Association of Enzymatically Active Tyrosine-phosphorylated ZAP-70 with the Crk Adapter Proteins
J. Biol. Chem. 1999 274: 21519-21527. [Abstract] [Full Text] [PDF]  

Kaname Nakatani, Devon A. Thompson, Andreas Barthel, Hiroshi Sakaue, Wei Liu, Ronald J. Weigel, and Richard A. Roth

Up-regulation of Akt3 in Estrogen Receptor-deficient Breast Cancers and Androgen-independent Prostate Cancer Lines
J. Biol. Chem. 1999 274: 21528-21532. [Abstract] [Full Text] [PDF]  

Nathalie Augé, Mariana Nikolova-Karakashian, Stéphane Carpentier, Sampath Parthasarathy, Anne Nègre-Salvayre, Robert Salvayre, Alfred H. Merrill Jr., and Thierry Levade

Role of Sphingosine 1-Phosphate in the Mitogenesis Induced by Oxidized Low Density Lipoprotein in Smooth Muscle Cells via Activation of Sphingomyelinase, Ceramidase, and Sphingosine Kinase
J. Biol. Chem. 1999 274: 21533-21538. [Abstract] [Full Text] [PDF]  

H. Helen Lin, Mark D. Zentner, Huei-Li Lily Ho, Kwang-Jin Kim, and David K. Ann

The Gene Expression of the Amiloride-sensitive Epithelial Sodium Channel -Subunit Is Regulated by Antagonistic Effects between Glucocorticoid Hormone and Ras Pathways in Salivary Epithelial Cells
J. Biol. Chem. 1999 274: 21544-21554. [Abstract] [Full Text] [PDF]  

Daniel J. Dairaghi, Rong A. Fan, Brian E. McMaster, Michael R. Hanley, and Thomas J. Schall

HHV8-encoded vMIP-I Selectively Engages Chemokine Receptor CCR8. AGONIST AND ANTAGONIST PROFILES OF VIRAL CHEMOKINES
J. Biol. Chem. 1999 274: 21569-21574. [Abstract] [Full Text] [PDF]  

Nisar Pampori, Takaaki Hato, Dwayne G. Stupack, Sallouha Aidoudi, David A. Cheresh, Glen R. Nemerow, and Sanford J. Shattil

Mechanisms and Consequences of Affinity Modulation of Integrin _V3 Detected with a Novel Patch-engineered Monovalent Ligand
J. Biol. Chem. 1999 274: 21609-21616. [Abstract] [Full Text] [PDF]  

Akira Nishiyama, Minoru Matsui, Satoshi Iwata, Kiichi Hirota, Hiroshi Masutani, Hajime Nakamura, Yasushi Takagi, Hiroshi Sono, Yasuhiro Gon, and Junji Yodoi

Identification of Thioredoxin-binding Protein-2/Vitamin D₃ Up-regulated Protein 1 as a Negative Regulator of Thioredoxin Function and Expression
J. Biol. Chem. 1999 274: 21645-21650. [Abstract] [Full Text] [PDF]  

Wayne W. Poon, Robert J. Barkovich, Adam Y. Hsu, Adam Frankel, Peter T. Lee, Jennifer N. Shepherd, David C. Myles, and Catherine F. Clarke

Yeast and Rat Coq3 and Escherichia coli UbiG Polypeptides Catalyze Both O-Methyltransferase Steps in Coenzyme Q Biosynthesis
J. Biol. Chem. 1999 274: 21665-21672. [Abstract] [Full Text] [PDF]  

Eduard Korkotian, Andreas Schwarz, Dori Pelled, Günter Schwarzmann, Menahem Segal, and Anthony H. Futerman

Elevation of Intracellular Glucosylceramide Levels Results in an Increase in Endoplasmic Reticulum Density and in Functional Calcium Stores in Cultured Neurons
J. Biol. Chem. 1999 274: 21673-21678. [Abstract] [Full Text] [PDF]  

Barbara Nicke, Katharina Detjen, and Craig D. Logsdon

Muscarinic Cholinergic Receptors Activate Both Inhibitory and Stimulatory Growth Mechanisms in NIH3T3 Cells
J. Biol. Chem. 1999 274: 21701-21706. [Abstract] [Full Text] [PDF]  

Anne Seiler-Tuyns, Nathalie Dufour, and François Spertini

Human Tumor Necrosis Factor- Gene 3' Untranslated Region Confers Inducible Toxin Responsiveness to Homologous Promoter in Monocytic THP-1 Cells
J. Biol. Chem. 1999 274: 21714-21718. [Abstract] [Full Text] [PDF]  

Stephen T. Safrany, Stephen W. Ingram, Jared L. Cartwright, J. R. Falck, Alexander G. McLennan, Larry D. Barnes, and Stephen B. Shears

The Diadenosine Hexaphosphate Hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae Are Homologues of the Human Diphosphoinositol Polyphosphate Phosphohydrolase. OVERLAPPING SUBSTRATE SPECIFICITIES IN A MutT-TYPE PROTEIN
J. Biol. Chem. 1999 274: 21735-21740. [Abstract] [Full Text] [PDF]  

Laurent Ruel, Vuk Stambolic, Adnan Ali, Armen S. Manoukian, and James R. Woodgett

Regulation of the Protein Kinase Activity of Shaggy^Zeste-white3 by Components of the Wingless Pathway in Drosophila Cells and Embryos
J. Biol. Chem. 1999 274: 21790-21796. [Abstract] [Full Text] [PDF]  

Brian V. Geisbrecht, Dongyan Zhang, Horst Schulz, and Stephen J. Gould

Characterization of PECI, a Novel Monofunctional ³,²-Enoyl-CoA Isomerase of Mammalian Peroxisomes
J. Biol. Chem. 1999 274: 21797-21803. [Abstract] [Full Text] [PDF]  

Patrick Folly and Norbert Engel

Chlorophyll b to Chlorophyll a Conversion Precedes Chlorophyll Degradation in Hordeum vulgare L.
J. Biol. Chem. 1999 274: 21811-21816. [Abstract] [Full Text] [PDF]  

Anand K. Ganesan, Timothy S. Vincent, Joan C. Olson, and Joseph T. Barbieri

Pseudomonas aeruginosa Exoenzyme S Disrupts Ras-mediated Signal Transduction by Inhibiting Guanine Nucleotide Exchange Factor-catalyzed Nucleotide Exchange
J. Biol. Chem. 1999 274: 21823-21829. [Abstract] [Full Text] [PDF]  

Keiji Yamamoto, Quynh N. Dang, Scott P. Kennedy, Rapin Osathanondh, Ralph A. Kelly, and Richard T. Lee

Induction of Tenascin-C in Cardiac Myocytes by Mechanical Deformation. ROLE OF REACTIVE OXYGEN SPECIES
J. Biol. Chem. 1999 274: 21840-21846. [Abstract] [Full Text] [PDF]  

Laura M'Rabet, Paul J. Coffer, Rob M. F. Wolthuis, Fried Zwartkruis, Leo Koenderman, and Johannes L. Bos

Differential fMet-Leu-Phe- and Platelet-activating Factor-induced Signaling Toward Ral Activation in Primary Human Neutrophils
J. Biol. Chem. 1999 274: 21847-21852. [Abstract] [Full Text] [PDF]  

Hidemichi Watari, E. Joan Blanchette-Mackie, Nancy K. Dwyer, Michiko Watari, Edward B. Neufeld, Shutish Patel, Peter G. Pentchev, and Jerome F. Strauss III

Mutations in the Leucine Zipper Motif and Sterol-sensing Domain Inactivate the Niemann-Pick C1 Glycoprotein
J. Biol. Chem. 1999 274: 21861-21866. [Abstract] [Full Text] [PDF]  

Martin Haardt, Mohamed Benharouga, Delphine Lechardeur, Norbert Kartner, and Gergely L. Lukacs

C-terminal Truncations Destabilize the Cystic Fibrosis Transmembrane Conductance Regulator without Impairing Its Biogenesis. A NOVEL CLASS OF MUTATION
J. Biol. Chem. 1999 274: 21873-21877. [Abstract] [Full Text] [PDF]  

Yoshihiro Nishida, Cheryl B. Knudson, J. Jaap Nietfeld, Arkady Margulis, and Warren Knudson

Antisense Inhibition of Hyaluronan Synthase-2 in Human Articular Chondrocytes Inhibits Proteoglycan Retention and Matrix Assembly
J. Biol. Chem. 1999 274: 21893-21899. [Abstract] [Full Text] [PDF]  

Ángel Zúñiga, Josema Torres, Josefa Úbeda, and Rafael Pulido

Interaction of Mitogen-activated Protein Kinases with the Kinase Interaction Motif of the Tyrosine Phosphatase PTP-SL Provides Substrate Specificity and Retains ERK2 in the Cytoplasm
J. Biol. Chem. 1999 274: 21900-21907. [Abstract] [Full Text] [PDF]  

Shannon E. Dunn, Jennifer L. Burns, and Robin N. Michel

Calcineurin Is Required for Skeletal Muscle Hypertrophy
J. Biol. Chem. 1999 274: 21908-21912. [Abstract] [Full Text] [PDF]  

Claire Bastie, Dorte Holst, Danielle Gaillard, Chantal Jehl-Pietri, and Paul A. Grimaldi

Expression of Peroxisome Proliferator-activated Receptor PPAR Promotes Induction of PPAR and Adipocyte Differentiation in 3T3C2 Fibroblasts
J. Biol. Chem. 1999 274: 21920-21925. [Abstract] [Full Text] [PDF]  

Ulrich Laufs, Diego Marra, Koichi Node, and James K. Liao

3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors Attenuate Vascular Smooth Muscle Proliferation by Preventing Rho GTPase-induced Down-regulation of p27^Kip1
J. Biol. Chem. 1999 274: 21926-21931. [Abstract] [Full Text] [PDF]  

Yau-Jan Chyan, Burkhard Poeggeler, Rawhi A. Omar, Daniel G. Chain, Blas Frangione, Jorge Ghiso, and Miguel A. Pappolla

Potent Neuroprotective Properties against the Alzheimer -Amyloid by an Endogenous Melatonin-related Indole Structure, Indole-3-propionic Acid
J. Biol. Chem. 1999 274: 21937-21942. [Abstract] [Full Text] [PDF]  

Steven Jon Russell, Katherine A. Steger, and Stephen Albert Johnston

Subcellular Localization, Stoichiometry, and Protein Levels of 26 S Proteasome Subunits in Yeast
J. Biol. Chem. 1999 274: 21943-21952. [Abstract] [Full Text] [PDF]  

Carl D. Bortner and John A. Cidlowski

Caspase Independent/Dependent Regulation of K⁺, Cell Shrinkage, and Mitochondrial Membrane Potential during Lymphocyte Apoptosis
J. Biol. Chem. 1999 274: 21953-21962. [Abstract] [Full Text] [PDF]  

Nikolai G. Zelenski, Robert B. Rawson, Michael S. Brown, and Joseph L. Goldstein

Membrane Topology of S2P, a Protein Required for Intramembranous Cleavage of Sterol Regulatory Element-binding Proteins
J. Biol. Chem. 1999 274: 21973-21980. [Abstract] [Full Text] [PDF]  

Michael J. Spinella, Sarah J. Freemantle, David Sekula, Jeffrey H. Chang, Allison J. Christie, and Ethan Dmitrovsky

Retinoic Acid Promotes Ubiquitination and Proteolysis of Cyclin D1 during Induced Tumor Cell Differentiation
J. Biol. Chem. 1999 274: 22013-22018. [Abstract] [Full Text] [PDF]  

Makoto Funaki, Hideki Katagiri, Akira Kanda, Motonobu Anai, Masao Nawano, Takehide Ogihara, Kouichi Inukai, Yasushi Fukushima, Hiraku Ono, Yoshio Yazaki, Masatoshi Kikuchi, Yoshitomo Oka, and Tomoichiro Asano

p85/p110-type Phosphatidylinositol Kinase Phosphorylates Not Only the D-3, but Also the D-4 Position of the Inositol Ring
J. Biol. Chem. 1999 274: 22019-22024. [Abstract] [Full Text] [PDF]  

G. Lee Wilson, Brenda S. Dean, Gan Wang, and David A. Dean

Nuclear Import of Plasmid DNA in Digitonin-permeabilized Cells Requires Both Cytoplasmic Factors and Specific DNA Sequences
J. Biol. Chem. 1999 274: 22025-22032. [Abstract] [Full Text] [PDF]  

Hendrik Gille and Julian Downward

Multiple Ras Effector Pathways Contribute to G₁ Cell Cycle Progression
J. Biol. Chem. 1999 274: 22033-22040. [Abstract] [Full Text] [PDF]  

Jerome A. Roth, Byung-Gook Kim, Wen-Lang Lin, and Moon-Il Cho

Melatonin Promotes Osteoblast Differentiation and Bone Formation
J. Biol. Chem. 1999 274: 22041-22047. [Abstract] [Full Text] [PDF]  

Ya Wang, Xiang-Yang Zhou, Hongyan Wang, M. Saiful Huq, and George Iliakis

Roles of Replication Protein A and DNA-dependent Protein Kinase in the Regulation of DNA Replication following DNA Damage
J. Biol. Chem. 1999 274: 22060-22064. [Abstract] [Full Text] [PDF]  

Kristen Page, Jing Li, Joshua A. Hodge, Pai T. Liu, Terry L. Vanden Hoek, Lance B. Becker, Richard G. Pestell, Marsha R. Rosner, and Marc B. Hershenson

Characterization of a Rac1 Signaling Pathway to Cyclin D₁ Expression in Airway Smooth Muscle Cells
J. Biol. Chem. 1999 274: 22065-22071. [Abstract] [Full Text] [PDF]  

Sandro B. Rizoli, Ori D. Rotstein, and Andras Kapus

Cell Volume-dependent Regulation of L-selectin Shedding in Neutrophils. A ROLE FOR p38 MITOGEN-ACTIVATED PROTEIN KINASE
J. Biol. Chem. 1999 274: 22072-22080. [Abstract] [Full Text] [PDF]  

Danxin Wang, Wolfgang Sadée, and J. Mark Quillan

Calmodulin Binding to G Protein-coupling Domain of Opioid Receptors
J. Biol. Chem. 1999 274: 22081-22088. [Abstract] [Full Text] [PDF]  

Lars Rönnstrand, Agneta Siegbahn, Charlotte Rorsman, Matilda Johnell, Klaus Hansen, and Carl-Henrik Heldin

Overactivation of Phospholipase C-1 Renders Platelet-derived Growth Factor -Receptor-expressing Cells Independent of the Phosphatidylinositol 3-Kinase Pathway for Chemotaxis
J. Biol. Chem. 1999 274: 22089-22094. [Abstract] [Full Text] [PDF]  

Luisa W. Cheng and Olaf Schneewind

Yersinia enterocolitica Type III Secretion. ON THE ROLE OF SycE IN TARGETING YopE INTO HeLa CELLS
J. Biol. Chem. 1999 274: 22102-22108. [Abstract] [Full Text] [PDF]  

Enzymology

Christina Paulus, Susanne Hellebrand, Uwe Tessmer, Hans Wolf, Hans-Georg Kräusslich, and Ralf Wagner

Competitive Inhibition of Human Immunodeficiency Virus Type-1 Protease by the Gag-Pol Transframe Protein
J. Biol. Chem. 1999 274: 21539-21543. [Abstract] [Full Text] [PDF]  

Finn Werner, Tahir M. Razzaq, and Vincent Ellis

Tissue Plasminogen Activator Binds to Human Vascular Smooth Muscle Cells by a Novel Mechanism. EVIDENCE FOR A RECIPROCAL LINKAGE BETWEEN INHIBITION OF CATALYTIC ACTIVITY AND CELLULAR BINDING
J. Biol. Chem. 1999 274: 21555-21561. [Abstract] [Full Text] [PDF]  

Lynne M. Coluccio and Michael A. Geeves

Transient Kinetic Analysis of the 130-kDa Myosin I (MYR-1 Gene Product) from Rat Liver. A MYOSIN I DESIGNED FOR MAINTENANCE OF TENSION?
J. Biol. Chem. 1999 274: 21575-21580. [Abstract] [Full Text] [PDF]  

Hanka Symmank, Wolfram Saenger, and Frank Bernhard

Analysis of Engineered Multifunctional Peptide Synthetases. ENZYMATIC CHARACTERIZATION OF SURFACTIN SYNTHETASE DOMAINS IN HYBRID BIMODULAR SYSTEMS
J. Biol. Chem. 1999 274: 21581-21588. [Abstract] [Full Text] [PDF]  

Diego Sbrissa, Ognian C. Ikonomov, and Assia Shisheva

PIKfyve, a Mammalian Ortholog of Yeast Fab1p Lipid Kinase, Synthesizes 5-Phosphoinositides. EFFECT OF INSULIN
J. Biol. Chem. 1999 274: 21589-21597. [Abstract] [Full Text] [PDF]  

Alexander Lowenthal and Rachel Levy

Essential Requirement of Cytosolic Phospholipase A₂ for Activation of the H⁺ Channel in Phagocyte-like Cells
J. Biol. Chem. 1999 274: 21603-21608. [Abstract] [Full Text] [PDF]  

Ignacio Rodríguez-Crespo, Clinton R. Nishida, Giselle M. Knudsen, and Paul R. Ortiz de Montellano

Mutation of the Five Conserved Histidines in the Endothelial Nitric-oxide Synthase Hemoprotein Domain. NO EVIDENCE FOR A NON-HEME METAL REQUIREMENT FOR CATALYSIS
J. Biol. Chem. 1999 274: 21617-21624. [Abstract] [Full Text] [PDF]  

Stephane Olland and James C. Wang

Catalysis of ATP Hydrolysis by Two NH₂-terminal Fragments of Yeast DNA Topoisomerase II
J. Biol. Chem. 1999 274: 21688-21694. [Abstract] [Full Text] [PDF]  

Ah-lim Tsai, Gang Wu, Graham Palmer, Bijan Bambai, James A. Koehn, Paul J. Marshall, and Richard J. Kulmacz

Rapid Kinetics of Tyrosyl Radical Formation and Heme Redox State Changes in Prostaglandin H Synthase-1 and -2
J. Biol. Chem. 1999 274: 21695-21700. [Abstract] [Full Text] [PDF]  

Fadi F. Hamdan and Paula Ribeiro

Characterization of a Stable Form of Tryptophan Hydroxylase from the Human Parasite Schistosoma mansoni
J. Biol. Chem. 1999 274: 21746-21754. [Abstract] [Full Text] [PDF]  

Sary Ben-Shahar, Arthur Komlosh, Eran Nadav, Isabella Shaked, Tamar Ziv, Arie Admon, George N. DeMartino, and Yuval Reiss

26 S Proteasome-mediated Production of an Authentic Major Histocompatibility Class I-restricted Epitope from an Intact Protein Substrate
J. Biol. Chem. 1999 274: 21963-21972. [Abstract] [Full Text] [PDF]  

Jon W. Lomasney, Hwei-Fang Cheng, Steve R. Roffler, and Klim King

Activation of Phospholipase C 1 through C2 Domain by a Ca²⁺-Enzyme-Phosphatidylserine Ternary Complex
J. Biol. Chem. 1999 274: 21995-22001. [Abstract] [Full Text] [PDF]  

Douglas B. Jordan, Karen O. Bacot, Thomas J. Carlson, Martin Kessel, and Paul V. Viitanen

Plant Riboflavin Biosynthesis. CLONING, CHLOROPLAST LOCALIZATION, EXPRESSION, PURIFICATION, AND PARTIAL CHARACTERIZATION OF SPINACH LUMAZINE SYNTHASE
J. Biol. Chem. 1999 274: 22114-22121. [Abstract] [Full Text] [PDF]  

Membranes and Bioenergetics

Thomas Zeuthen and Dan Arne Klaerke

Transport of Water and Glycerol in Aquaporin 3 Is Gated by H⁺
J. Biol. Chem. 1999 274: 21631-21636. [Abstract] [Full Text] [PDF]  

Anne Marjamäki, Heini Frang, Marjo Pihlavisto, Anna-Marja Hoffrén, Tiina Salminen, Mark S. Johnson, Jaana Kallio, Jonathan A. Javitch, and Mika Scheinin

Chloroethylclonidine and 2-Aminoethyl Methanethiosulfonate Recognize Two Different Conformations of the Human _2A-Adrenergic Receptor
J. Biol. Chem. 1999 274: 21867-21872. [Abstract] [Full Text] [PDF]  

Manfred Grabner, Robert T. Dirksen, Norio Suda, and Kurt G. Beam

The II-III Loop of the Skeletal Muscle Dihydropyridine Receptor Is Responsible for the Bi-directional Coupling with the Ryanodine Receptor
J. Biol. Chem. 1999 274: 21913-21919. [Abstract] [Full Text] [PDF]  

Ilia Voskoboinik, Daniel Strausak, Mark Greenough, Hilary Brooks, Michael Petris, Suzanne Smith, Julian F. Mercer, and James Camakaris

Functional Analysis of the N-terminal CXXC Metal-binding Motifs in the Human Menkes Copper-transporting P-type ATPase Expressed in Cultured Mammalian Cells
J. Biol. Chem. 1999 274: 22008-22012. [Abstract] [Full Text] [PDF]  

Meike Kuschel, Ying-Ying Zhou, Heping Cheng, Sheng-Jun Zhang, Ye Chen, Edward G. Lakatta, and Rui-Ping Xiao

G_i Protein-mediated Functional Compartmentalization of Cardiac ₂-Adrenergic Signaling
J. Biol. Chem. 1999 274: 22048-22052. [Abstract] [Full Text] [PDF]  

Priti Hegde, Gang-Gou Gu, Dong Chen, Stephen J. Free, and Satpal Singh

Mutational Analysis of the Shab-encoded Delayed Rectifier K⁺ Channels in Drosophila
J. Biol. Chem. 1999 274: 22109-22113. [Abstract] [Full Text] [PDF]  

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Christoph Buettner, John W. Harney, and Marla J. Berry

The Caenorhabditis elegans Homologue of Thioredoxin Reductase Contains a Selenocysteine Insertion Sequence (SECIS) Element That Differs from Mammalian SECIS Elements but Directs Selenocysteine Incorporation
J. Biol. Chem. 1999 274: 21598-21602. [Abstract] [Full Text] [PDF]  

Xiao-Feng Le, Yoram Groner, Steve M. Kornblau, Yun Gu, Walter N. Hittelman, Ditsa Levanon, Kapil Mehta, Ralph B. Arlinghaus, and Kun-Sang Chang

Regulation of AML2/CBFA3 in Hematopoietic Cells through the Retinoic Acid Receptor -Dependent Signaling Pathway
J. Biol. Chem. 1999 274: 21651-21658. [Abstract] [Full Text] [PDF]  

Teresa Wilson, Shawn Guerrette, and Richard Fishel

Dissociation of Mismatch Recognition and ATPase Activity by hMSH2-hMSH3
J. Biol. Chem. 1999 274: 21659-21664. [Abstract] [Full Text] [PDF]  

Zachary B. Mackey, Claude Niedergang, Josiane Ménissier-de Murcia, John Leppard, Karin Au, Jingwen Chen, Gilbert de Murcia, and Alan E. Tomkinson

DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly(ADP-ribose) Polymerase. IDENTIFICATION OF TWO FUNCTIONALLY DISTINCT DNA BINDING REGIONS WITHIN DNA LIGASE III
J. Biol. Chem. 1999 274: 21679-21687. [Abstract] [Full Text] [PDF]  

Irit Paz, Lilach Abramovitz, and Mordechai Choder

Starved Saccharomyces cerevisiae Cells Have the Capacity to Support Internal Initiation of Translation
J. Biol. Chem. 1999 274: 21741-21745. [Abstract] [Full Text] [PDF]  

Steven Broitman, Olga Amosova, Nina G. Dolinnaya, and Jacques R. Fresco

Repairing the Sickle Cell Mutation. I. SPECIFIC COVALENT BINDING OF A PHOTOREACTIVE THIRD STRAND TO THE MUTATED BASE PAIR
J. Biol. Chem. 1999 274: 21763-21768. [Abstract] [Full Text] [PDF]  

Gabriela Schmajuk, Halina Sierakowska, and Ryszard Kole

Antisense Oligonucleotides with Different Backbones. MODIFICATION OF SPLICING PATHWAYS AND EFFICACY OF UPTAKE
J. Biol. Chem. 1999 274: 21783-21789. [Abstract] [Full Text] [PDF]  

Shireen R. Lamandé, Katherine A. Shields, Andrew J. Kornberg, Lloyd K. Shield, and John F. Bateman

Bethlem Myopathy and Engineered Collagen VI Triple Helical Deletions Prevent Intracellular Multimer Assembly and Protein Secretion
J. Biol. Chem. 1999 274: 21817-21822. [Abstract] [Full Text] [PDF]  

John H. Lee, Tracy J. Baker, Lara K. Mahal, Joseph Zabner, Carolyn R. Bertozzi, David F. Wiemer, and Michael J. Welsh

Engineering Novel Cell Surface Receptors for Virus-mediated Gene Transfer
J. Biol. Chem. 1999 274: 21878-21884. [Abstract] [Full Text] [PDF]  

Amy E. Schmidt, Trissa Miller, Susan L. Schmidt, Ramin Shiekhattar, and Ali Shilatifard

Cloning and Characterization of the EAP30 Subunit of the ELL Complex That Confers Derepression of Transcription by RNA Polymerase II
J. Biol. Chem. 1999 274: 21981-21985. [Abstract] [Full Text] [PDF]  

Kristin Brevik Andersson, Tone Berge, Vilborg Matre, and Odd S. Gabrielsen

Sequence Selectivity of c-Myb in Vivo. RESOLUTION OF A DNA TARGET SPECIFICITY PARADOX
J. Biol. Chem. 1999 274: 21986-21994. [Abstract] [Full Text] [PDF]  

Masaaki Kanemori, Hideki Yanagi, and Takashi Yura

Marked Instability of the ³² Heat Shock Transcription Factor at High Temperature. IMPLICATIONS FOR HEAT SHOCK REGULATION
J. Biol. Chem. 1999 274: 22002-22007. [Abstract] [Full Text] [PDF]  

Ann Mineo Kania, Ernst Reichenberger, Scott T. Baur, Nadeem Y. Karimbux, Reginald W. Taylor, Bjorn R. Olsen, and Ichiro Nishimura

Structural Variation of Type XII Collagen at Its Carboxyl-terminal NC1 Domain Generated by Tissue-specific Alternative Splicing
J. Biol. Chem. 1999 274: 22053-22059. [Abstract] [Full Text] [PDF]  

Yanlin Wang, Wendy Devereux, Tracy Murray Stewart, and Robert A. Casero Jr.

Cloning and Characterization of Human Polyamine-modulated Factor-1, a Transcriptional Cofactor That Regulates the Transcription of the Spermidine/Spermine N¹-Acetyltransferase Gene
J. Biol. Chem. 1999 274: 22095-22101. [Abstract] [Full Text] [PDF]  

Protein Chemistry and Structure

Byoung C. Park, Young C. Lee, and Charles A. Strott

Identification by Chimera Formation and Site-selected Mutagenesis of a Key Amino Acid Residue Involved in Determining Stereospecificity of Guinea Pig 3-Hydroxysteroid Sulfotransferase Isoforms
J. Biol. Chem. 1999 274: 21562-21568. [Abstract] [Full Text] [PDF]  

Xavier Brazzolotto, Jacques Gaillard, Kostas Pantopoulos, Matthias W. Hentze, and Jean-Marc Moulis

Human Cytoplasmic Aconitase (Iron Regulatory Protein 1) Is Converted into Its [3Fe-4S] Form by Hydrogen Peroxide in Vitro but Is Not Activated for Iron-responsive Element Binding
J. Biol. Chem. 1999 274: 21625-21630. [Abstract] [Full Text] [PDF]  

Michael Tseng, Nades Palaniyar, Wandong Zhang, and David H. Evans

DNA Binding and Aggregation Properties of the Vaccinia Virus I3L Gene Product
J. Biol. Chem. 1999 274: 21637-21644. [Abstract] [Full Text] [PDF]  

Wendy J. Wu, Bernadette Vrhovski, and Anthony S. Weiss

Glycosaminoglycans Mediate the Coacervation of Human Tropoelastin through Dominant Charge Interactions Involving Lysine Side Chains
J. Biol. Chem. 1999 274: 21719-21724. [Abstract] [Full Text] [PDF]  

Alberto Martin, Hing Wo Tsui, Marc J. Shulman, David Isenman, and Florence W. L. Tsui

Murine SHP-1 Splice Variants with Altered Src Homology 2 (SH2) Domains. IMPLICATIONS FOR THE SH2-MEDIATED INTRAMOLECULAR REGULATION OF SHP-1
J. Biol. Chem. 1999 274: 21725-21734. [Abstract] [Full Text] [PDF]  

Anant B. Patel, Sudha Srivastava, and Ratna S. Phadke

Interaction of 7-Hydroxy-8-(phenylazo)1,3-naphthalenedisulfonate with Bovine Plasma Albumin. SPECTROSCOPIC STUDIES
J. Biol. Chem. 1999 274: 21755-21762. [Abstract] [Full Text] [PDF]  

Jay J. Thelen, Michael G. Muszynski, Nancy R. David, Michael H. Luethy, Thomas E. Elthon, Jan A. Miernyk, and Douglas D. Randall

The Dihydrolipoamide S-Acetyltransferase Subunit of the Mitochondrial Pyruvate Dehydrogenase Complex from Maize Contains a Single Lipoyl Domain
J. Biol. Chem. 1999 274: 21769-21775. [Abstract] [Full Text] [PDF]  

Scott Napper, Louis T. J. Delbaere, and E. Bruce Waygood

The Aspartyl Replacement of the Active Site Histidine in Histidine-containing Protein, HPr, of the Escherichia coli Phosphoenolpyruvate:Sugar Phosphotransferase System Can Accept and Donate a Phosphoryl Group. SPONTANEOUS DEPHOSPHORYLATION OF ACYL-PHOSPHATE AUTOCATALYZES AN INTERNAL CYCLIZATION
J. Biol. Chem. 1999 274: 21776-21782. [Abstract] [Full Text] [PDF]  

Paul M. M. Weers, Vasanthy Narayanaswami, Cyril M. Kay, and Robert O. Ryan

Interaction of an Exchangeable Apolipoprotein with Phospholipid Vesicles and Lipoprotein Particles. ROLE OF LEUCINES 32, 34, AND 95 IN LOCUSTA MIGRATORIA APOLIPOPHORIN III
J. Biol. Chem. 1999 274: 21804-21810. [Abstract] [Full Text] [PDF]  

Eveline Fonzé, Marcel Vermeire, Martine Nguyen-Distèche, Robert Brasseur, and Paulette Charlier

The Crystal Structure of a Penicilloyl-serine Transferase of Intermediate Penicillin Sensitivity. THE DD-TRANSPEPTIDASE OF STREPTOMYCES K15
J. Biol. Chem. 1999 274: 21853-21860. [Abstract] [Full Text] [PDF]  

Heiko Rauer, Michael Pennington, Michael Cahalan, and K. George Chandy

Structural Conservation of the Pores of Calcium-activated and Voltage-gated Potassium Channels Determined by a Sea Anemone Toxin
J. Biol. Chem. 1999 274: 21885-21892. [Abstract] [Full Text] [PDF]  

Sharon L. Schendel, Rustam Azimov, Adam Godzik, Bruce L. Kagan, and John C. Reed

Ion Channel Activity of the BH3 Only Bcl-2 Family Member, BID
J. Biol. Chem. 1999 274: 21932-21936. [Abstract] [Full Text] [PDF]  

Additions and Corrections

David C. Edwards and Gordon N. Gill

Structural features of LIM kinase that control effects on the actin cytoskeleton.
J. Biol. Chem. 1999 274: 22122. [Full Text] [PDF]  

Cholesterol biosynthesis from lanosterol. Molecular cloning, tissue distribution, expression, chromosomal localization, and regulation of rat 7-dehydrocholesterol reductase, a Smith-Lemli-Opitz syndrome-related protein.
J. Biol. Chem. 1999 274: 22122. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstracts' button. To see one abstract at a time, click its [Abstract] link.