Minireviews

Stephen M. Prescott

A Thematic Series on Oxidation of Lipids as a Source of Messengers
J. Biol. Chem. 1999 274: 22901. [Full Text] [PDF]  

Lawrence J. Marnett, Scott W. Rowlinson, Douglas C. Goodwin, Amit S. Kalgutkar, and Cheryl A. Lanzo

Arachidonic Acid Oxygenation by COX-1 and COX-2. MECHANISMS OF CATALYSIS AND INHIBITION
J. Biol. Chem. 1999 274: 22903-22906. [Full Text] [PDF] [Data Supplement]  

Communications

Jussi M. Halleen, Seija Räisänen, Jari J. Salo, Sakamuri V. Reddy, G. David Roodman, Teuvo A. Hentunen, Petri P. Lehenkari, Helena Kaija, Pirkko Vihko, and H. Kalervo Väänänen

Intracellular Fragmentation of Bone Resorption Products by Reactive Oxygen Species Generated by Osteoclastic Tartrate-resistant Acid Phosphatase
J. Biol. Chem. 1999 274: 22907-22910. [Abstract] [Full Text] [PDF]  

Edward W. Harhaj and Shao-Cong Sun

IKK Serves as a Docking Subunit of the IB Kinase (IKK) and Mediates Interaction of IKK with the Human T-cell Leukemia Virus Tax Protein
J. Biol. Chem. 1999 274: 22911-22914. [Abstract] [Full Text] [PDF]  

Tetsuya Okajima, Kumi Yoshida, Tadao Kondo, and Koichi Furukawa

Human Homolog of Caenorhabditis elegans sqv-3 Gene Is Galactosyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans
J. Biol. Chem. 1999 274: 22915-22918. [Abstract] [Full Text] [PDF]  

Celine Prunier, Anne Mazars, Veerle Noë, Erik Bruyneel, Marc Mareel, Christian Gespach, and Azeddine Atfi

Evidence That Smad2 Is a Tumor Suppressor Implicated in the Control of Cellular Invasion
J. Biol. Chem. 1999 274: 22919-22922. [Abstract] [Full Text] [PDF]  

Carbohydrates, Lipids, and Other Natural Products

Jeong Heon Ko, Eiji Miyoshi, Katsuhisa Noda, Atsuko Ekuni, Rujun Kang, Yoshitaka Ikeda, and Naoyuki Taniguchi

Regulation of the GnT-V Promoter by Transcription Factor Ets-1 in Various Cancer Cell Lines
J. Biol. Chem. 1999 274: 22941-22948. [Abstract] [Full Text] [PDF]  

Takashi Angata, Daisuke Nakata, Tsukasa Matsuda, Ken Kitajima, and Frederic A. Troy II

Biosynthesis of KDN (2-Keto-3-deoxy-D-glycero-D-galacto-nononic acid). IDENTIFICATION AND CHARACTERIZATION OF A KDN-9-PHOSPHATE SYNTHETASE ACTIVITY FROM TROUT TESTIS
J. Biol. Chem. 1999 274: 22949-22956. [Abstract] [Full Text] [PDF]  

M. Mahbubur Rahman, Jean Guard-Petter, Kokila Asokan, Colin Hughes, and Russell W. Carlson

The Structure of the Colony Migration Factor from Pathogenic Proteus mirabilis. A CAPSULAR POLYSACCHARIDE THAT FACILITATES SWARMING
J. Biol. Chem. 1999 274: 22993-22998. [Abstract] [Full Text] [PDF]  

Pallavi R. Devchand, Abdelmadjid K. Hihi, Mai Perroud, Wolf-Dieter D. Schleuning, Bruce M. Spiegelman, and Walter Wahli

Chemical Probes That Differentially Modulate Peroxisome Proliferator-activated Receptor  and BLTR, Nuclear and Cell Surface Receptors for Leukotriene B₄
J. Biol. Chem. 1999 274: 23341-23348. [Abstract] [Full Text] [PDF]  

Jing Xu, Manabu T. Nakamura, Hyekyung P. Cho, and Steven D. Clarke

Sterol Regulatory Element Binding Protein-1 Expression Is Suppressed by Dietary Polyunsaturated Fatty Acids. A MECHANISM FOR THE COORDINATE SUPPRESSION OF LIPOGENIC GENES BY POLYUNSATURATED FATS
J. Biol. Chem. 1999 274: 23577-23583. [Abstract] [Full Text] [PDF]  

Cell Biology and Metabolism

Sergey A. Trushin, Kevin N. Pennington, Alicia Algeciras-Schimnich, and Carlos V. Paya

Protein Kinase C and Calcineurin Synergize to Activate IB Kinase and NF-B in T Lymphocytes
J. Biol. Chem. 1999 274: 22923-22931. [Abstract] [Full Text] [PDF]  

Abdelaziz Heddi, Georges Stepien, Paul J. Benke, and Douglas C. Wallace

Coordinate Induction of Energy Gene Expression in Tissues of Mitochondrial Disease Patients
J. Biol. Chem. 1999 274: 22968-22976. [Abstract] [Full Text] [PDF]  

Ruey-Hwa Chen, Ming-Cheng Chang, Yi-Hsien Su, Yuh-Tyng Tsai, and Min-Liang Kuo

Interleukin-6 Inhibits Transforming Growth Factor--induced Apoptosis through the Phosphatidylinositol 3-Kinase/Akt and Signal Transducers and Activators of Transcription 3 Pathways
J. Biol. Chem. 1999 274: 23013-23019. [Abstract] [Full Text] [PDF]  

Heather A. Curry, Regina A. Clemens, Sunita Shah, Christopher M. Bradbury, Ana Botero, Prabhat Goswami, and David Gius

Heat Shock Inhibits Radiation-induced Activation of NF-B via Inhibition of I-B Kinase
J. Biol. Chem. 1999 274: 23061-23067. [Abstract] [Full Text] [PDF]  

Patrick G. Swann, Sandra Odom, Yong-Jie Zhou, Zoltan Szallasi, Peter M. Blumberg, Petr Draber, and Juan Rivera

Requirement for a Negative Charge at Threonine 60 of the FcR for Complete Activation of Syk
J. Biol. Chem. 1999 274: 23068-23077. [Abstract] [Full Text] [PDF]  

Osamu Moro, Kaori Wakita, Manami Ohnuma, Sumiko Denda, Ethan A. Lerner, and Masahiro Tajima

Functional Characterization of Structural Alterations in the Sequence of the Vasodilatory Peptide Maxadilan Yields a Pituitary Adenylate Cyclase-activating Peptide Type 1 Receptor-specific Antagonist
J. Biol. Chem. 1999 274: 23103-23110. [Abstract] [Full Text] [PDF]  

Mehdi Mesri and Dario C. Altieri

Leukocyte Microparticles Stimulate Endothelial Cell Cytokine Release and Tissue Factor Induction in a JNK1 Signaling Pathway
J. Biol. Chem. 1999 274: 23111-23118. [Abstract] [Full Text] [PDF]  

Mhairi A. Skinner and Alan G. Wildeman

₁ Integrin Binds the 16-kDa Subunit of Vacuolar H⁺-ATPase at a Site Important for Human Papillomavirus E5 and Platelet-derived Growth Factor Signaling
J. Biol. Chem. 1999 274: 23119-23127. [Abstract] [Full Text] [PDF]  

Dora Cavallo, Debbie Rudy, Abbas Mohammadi, Joseph Macri, and Khosrow Adeli

Studies on Degradative Mechanisms Mediating Post-translational Fragmentation of Apolipoprotein B and the Generation of the 70-kDa Fragment
J. Biol. Chem. 1999 274: 23135-23143. [Abstract] [Full Text] [PDF]  

Phil Oh and Jan E. Schnitzer

Immunoisolation of Caveolae with High Affinity Antibody Binding to the Oligomeric Caveolin Cage. TOWARD UNDERSTANDING THE BASIS OF PURIFICATION
J. Biol. Chem. 1999 274: 23144-23154. [Abstract] [Full Text] [PDF]  

Keisuke Wakasugi and Paul Schimmel

Highly Differentiated Motifs Responsible for Two Cytokine Activities of a Split Human tRNA Synthetase
J. Biol. Chem. 1999 274: 23155-23159. [Abstract] [Full Text] [PDF]  

Steven C. Rumsey, Richard W. Welch, H. Martin Garraffo, Ping Ge, Shou-Fu Lu, Arthur T. Crossman, Kenneth L. Kirk, and Mark Levine

Specificity of Ascorbate Analogs for Ascorbate Transport. SYNTHESIS AND DETECTION OF [¹²⁵I]6-DEOXY-6-IODO-L-ASCORBIC ACID AND CHARACTERIZATION OF ITS ASCORBATE-SPECIFIC TRANSPORT PROPERTIES
J. Biol. Chem. 1999 274: 23215-23222. [Abstract] [Full Text] [PDF]  

Ping-yuan Wang and Robert S. Munford

CD14-dependent Internalization and Metabolism of Extracellular Phosphatidylinositol by Monocytes
J. Biol. Chem. 1999 274: 23235-23241. [Abstract] [Full Text] [PDF]  

Anita K. Harvey, Xiao-Peng Yu, Charles A. Frolik, and Srinivasan Chandrasekhar

Parathyroid Hormone-(1-34) Enhances Aggrecan Synthesis via an Insulin-like Growth Factor-I Pathway
J. Biol. Chem. 1999 274: 23249-23255. [Abstract] [Full Text] [PDF]  

Thomas L. Brown, Supriya Patil, Carol D. Cianci, Jon S. Morrow, and Philip H. Howe

Transforming Growth Factor  Induces Caspase 3-independent Cleavage of II-Spectrin (-Fodrin) Coincident with Apoptosis
J. Biol. Chem. 1999 274: 23256-23262. [Abstract] [Full Text] [PDF]  

D. Alex Groarke, Shelagh Wilson, Cornelius Krasel, and Graeme Milligan

Visualization of Agonist-induced Association and Trafficking of Green Fluorescent Protein-tagged Forms of Both -Arrestin-1 and the Thyrotropin-releasing Hormone Receptor-1
J. Biol. Chem. 1999 274: 23263-23269. [Abstract] [Full Text] [PDF]  

Jonathan B. Zuckerman, Xiyin Chen, Joely D. Jacobs, Baofeng Hu, Thomas R. Kleyman, and Peter R. Smith

Association of the Epithelial Sodium Channel with Apx and -Spectrin in A6 Renal Epithelial Cells
J. Biol. Chem. 1999 274: 23286-23295. [Abstract] [Full Text] [PDF]  

Brigitte Gay, Stéphanie Suarez, Christine Weber, Joseph Rahuel, Doriano Fabbro, Pascal Furet, Giorgio Caravatti, and Joseph Schoepfer

Effect of Potent and Selective Inhibitors of the Grb2 SH2 Domain on Cell Motility
J. Biol. Chem. 1999 274: 23311-23315. [Abstract] [Full Text] [PDF]  

Vijaya Chaturvedi, Jian-Zhong Qin, Mitchell F. Denning, Divaker Choubey, Manuel O. Diaz, and Brian J. Nickoloff

Apoptosis in Proliferating, Senescent, and Immortalized Keratinocytes
J. Biol. Chem. 1999 274: 23358-23367. [Abstract] [Full Text] [PDF]  

Hebe M. Guardiola-Diaz, Stefan Rehnmark, Nobuteru Usuda, Tatjana Albrektsen, Dorothee Feltkamp, Jan-Åke Gustafsson, and Stefan E. H. Alexson

Rat Peroxisome Proliferator-activated Receptors and Brown Adipose Tissue Function during Cold Acclimatization
J. Biol. Chem. 1999 274: 23368-23377. [Abstract] [Full Text] [PDF]  

Gianluigi Zanusso, Robert B. Petersen, Taocong Jin, Yi Jing, Rima Kanoush, Sergio Ferrari, Pierluigi Gambetti, and Neena Singh

Proteasomal Degradation and N-terminal Protease Resistance of the Codon 145 Mutant Prion Protein
J. Biol. Chem. 1999 274: 23396-23404. [Abstract] [Full Text] [PDF]  

Jeffrey A. Knauf, Rosella Elisei, Daria Mochly-Rosen, Tamar Liron, Xiao-Ning Chen, Rivkah Gonsky, Julie R. Korenberg, and James A. Fagin

Involvement of Protein Kinase C (PKC) in Thyroid Cell Death. A TRUNCATED CHIMERIC PKC CLONED FROM A THYROID CANCER CELL LINE PROTECTS THYROID CELLS FROM APOPTOSIS
J. Biol. Chem. 1999 274: 23414-23425. [Abstract] [Full Text] [PDF]  

Andréa LeBlanc, Hui Liu, Cynthia Goodyer, Catherine Bergeron, and Jennifer Hammond

Caspase-6 Role in Apoptosis of Human Neurons, Amyloidogenesis, and Alzheimer's Disease
J. Biol. Chem. 1999 274: 23426-23436. [Abstract] [Full Text] [PDF]  

David A. Antonetti, Alistair J. Barber, Leigh Ann Hollinger, Ellen B. Wolpert, and Thomas W. Gardner

Vascular Endothelial Growth Factor Induces Rapid Phosphorylation of Tight Junction Proteins Occludin and Zonula Occluden 1. A POTENTIAL MECHANISM FOR VASCULAR PERMEABILITY IN DIABETIC RETINOPATHY AND TUMORS
J. Biol. Chem. 1999 274: 23463-23467. [Abstract] [Full Text] [PDF]  

Susan L. Kozak, Shawn E. Kuhmann, Emily J. Platt, and David Kabat

Roles of CD4 and Coreceptors in Binding, Endocytosis, and Proteolysis of gp120 Envelope Glycoproteins Derived from Human Immunodeficiency Virus Type 1
J. Biol. Chem. 1999 274: 23499-23507. [Abstract] [Full Text] [PDF]  

Amale Laouar, David Glesne, and Eliezer Huberman

Involvement of Protein Kinase C- and Ceramide in Tumor Necrosis Factor--induced but Not Fas-induced Apoptosis of Human Myeloid Leukemia Cells
J. Biol. Chem. 1999 274: 23526-23534. [Abstract] [Full Text] [PDF]  

Archana Deshpande and Sanjay Sonar

Bacterioopsin-triggered Retinal Biosynthesis Is Inhibited by Bacteriorhodopsin Formation in Halobacterium salinarium
J. Biol. Chem. 1999 274: 23535-23540. [Abstract] [Full Text] [PDF]  

Marcia A. McAleer, Maria A. Breen, Nina L. White, and Nicholas Matthews

pABC11 (Also Known as MOAT-C and MRP5), a Member of the ABC Family of Proteins, Has Anion Transporter Activity but Does Not Confer Multidrug Resistance When Overexpressed in Human Embryonic Kidney 293 Cells
J. Biol. Chem. 1999 274: 23541-23548. [Abstract] [Full Text] [PDF]  

Christiane Bachmann, Lieselore Fischer, Ulrich Walter, and Matthias Reinhard

The EVH2 Domain of the Vasodilator-stimulated Phosphoprotein Mediates Tetramerization, F-actin Binding, and Actin Bundle Formation
J. Biol. Chem. 1999 274: 23549-23557. [Abstract] [Full Text] [PDF]  

Wei Guo, Althea Grant, and Peter Novick

Exo84p Is an Exocyst Protein Essential for Secretion
J. Biol. Chem. 1999 274: 23558-23564. [Abstract] [Full Text] [PDF]  

Aysha H. Osmani, Gregory S. May, and Stephen A. Osmani

The Extremely Conserved pyroA Gene of Aspergillus nidulans Is Required for Pyridoxine Synthesis and Is Required Indirectly for Resistance to Photosensitizers
J. Biol. Chem. 1999 274: 23565-23569. [Abstract] [Full Text] [PDF]  

P. William Conrad, Randall T. Rust, Jiahuai Han, David E. Millhorn, and Dana Beitner-Johnson

Selective Activation of p38 and p38 by Hypoxia. ROLE IN REGULATION OF CYCLIN D1 BY HYPOXIA IN PC12 CELLS
J. Biol. Chem. 1999 274: 23570-23576. [Abstract] [Full Text] [PDF]  

Carole Gallet, Jean-Philippe Rosa, Aïda Habib, Marilyne Lebret, Sylviane Lévy-Tolédano, and Jacques Maclouf

Tyrosine Phosphorylation of Cortactin Associated with Syk Accompanies Thromboxane Analogue-induced Platelet Shape Change
J. Biol. Chem. 1999 274: 23610-23616. [Abstract] [Full Text] [PDF]  

James D. Bretz, Michal Rymaszewski, Patricia L. Arscott, Andrzej Myc, Kenneth B. Ain, Norman W. Thompson, and James R. Baker Jr.

TRAIL Death Pathway Expression and Induction in Thyroid Follicular Cells
J. Biol. Chem. 1999 274: 23627-23632. [Abstract] [Full Text] [PDF]  

Rui Lin, Richard A. Cerione, and Danny Manor

Specific Contributions of the Small GTPases Rho, Rac, and Cdc42 to Dbl Transformation
J. Biol. Chem. 1999 274: 23633-23641. [Abstract] [Full Text] [PDF]  

Junko Fujita-Yoshigaki, Yoko Dohke, Miki Hara-Yokoyama, Shunsuke Furuyama, and Hiroshi Sugiya

Presence of a Complex Containing Vesicle-associated Membrane Protein 2 in Rat Parotid Acinar Cells and Its Disassembly upon Activation of cAMP-dependent Protein Kinase
J. Biol. Chem. 1999 274: 23642-23646. [Abstract] [Full Text] [PDF]  

Noemí Bronstein-Sitton, Lynn Wang, Leonor Cohen, and Michal Baniyash

Expression of the T Cell Antigen Receptor  Chain following Activation Is Controlled at Distinct Checkpoints. IMPLICATIONS FOR CELL SURFACE RECEPTOR DOWN-MODULATION AND RE-EXPRESSION
J. Biol. Chem. 1999 274: 23659-23665. [Abstract] [Full Text] [PDF]  

Enzymology

A. Hamid Boulares, Alexander G. Yakovlev, Vessela Ivanova, Bogdan A. Stoica, Geping Wang, Sudha Iyer, and Mark Smulson

Role of Poly(ADP-ribose) Polymerase (PARP) Cleavage in Apoptosis. CASPASE 3-RESISTANT PARP MUTANT INCREASES RATES OF APOPTOSIS IN TRANSFECTED CELLS
J. Biol. Chem. 1999 274: 22932-22940. [Abstract] [Full Text] [PDF]  

Yukio Nisimoto, Shabnam Motalebi, Chang-Hoon Han, and J. David Lambeth

The p67^phox Activation Domain Regulates Electron Flow from NADPH to Flavin in Flavocytochrome b₅₅₈
J. Biol. Chem. 1999 274: 22999-23005. [Abstract] [Full Text] [PDF]  

Sergei B. Vakulenko, Pascale Taibi-Tronche, Márta Tóth, Irina Massova, Stephen A. Lerner, and Shahriar Mobashery

Effects on Substrate Profile by Mutational Substitutions at Positions 164 and 179 of the Class A TEM_pUC19 -Lactamase from Escherichia coli
J. Biol. Chem. 1999 274: 23052-23060. [Abstract] [Full Text] [PDF]  

Nathaniel J. Cosper, Christina M. V. Stålhandske, Hideo Iwasaki, Tairo Oshima, Robert A. Scott, and Toshio Iwasaki

Structural Conservation of the Isolated Zinc Site in Archaeal Zinc-containing Ferredoxins as Revealed by X-ray Absorption Spectroscopic Analysis and Its Evolutionary Implications
J. Biol. Chem. 1999 274: 23160-23168. [Abstract] [Full Text] [PDF] [Data Supplement]  

Mitsuhiro Nakano, Tomotake Morita, Tomokazu Yamamoto, Hisashi Sano, Makoto Ashiuchi, Ryoji Masui, Seiki Kuramitsu, and Toshiharu Yagi

Purification, Molecular Cloning, and Catalytic Activity of Schizosaccharomyces pombe Pyridoxal Reductase. A POSSIBLE ADDITIONAL FAMILY IN THE ALDO-KETO REDUCTASE SUPERFAMILY
J. Biol. Chem. 1999 274: 23185-23190. [Abstract] [Full Text] [PDF]  

Damian J. Krysan, Nathan C. Rockwell, and Robert S. Fuller

Quantitative Characterization of Furin Specificity. ENERGETICS OF SUBSTRATE DISCRIMINATION USING AN INTERNALLY CONSISTENT SET OF HEXAPEPTIDYL METHYLCOUMARINAMIDES
J. Biol. Chem. 1999 274: 23229-23234. [Abstract] [Full Text] [PDF]  

John M. Louis, Ewald M. Wondrak, Alan R. Kimmel, Paul T. Wingfield, and Nashaat T. Nashed

Proteolytic Processing of HIV-1 Protease Precursor, Kinetics and Mechanism
J. Biol. Chem. 1999 274: 23437-23442. [Abstract] [Full Text] [PDF]  

M. Rafiq Islam, Shunji Tomatsu, Gul N. Shah, Jeffrey H. Grubb, Sanjeev Jain, and William. S. Sly

Active Site Residues of Human -Glucuronidase. EVIDENCE FOR GLU⁵⁴⁰ AS THE NUCLEOPHILE AND GLU⁴⁵¹ AS THE ACID-BASE RESIDUE
J. Biol. Chem. 1999 274: 23451-23455. [Abstract] [Full Text] [PDF]  

J. Richard Miller and Dale E. Edmondson

Influence of Flavin Analogue Structure on the Catalytic Activities and Flavinylation Reactions of Recombinant Human Liver Monoamine Oxidases A and B
J. Biol. Chem. 1999 274: 23515-23525. [Abstract] [Full Text] [PDF]  

Membranes and Bioenergetics

Franke Baymann, Francesca Zito, Richard Kuras, Limor Minai, Wolfgang Nitschke, and Francis-André Wollman

Functional Characterization of Chlamydomonas Mutants Defective in Cytochrome f Maturation
J. Biol. Chem. 1999 274: 22957-22967. [Abstract] [Full Text] [PDF]  

Jia Yeu Liu, Paul F. Miller, Jennifer Willard, and Eric R. Olson

Functional and Biochemical Characterization of Escherichia coli Sugar Efflux Transporters
J. Biol. Chem. 1999 274: 22977-22984. [Abstract] [Full Text] [PDF]  

Andrea N. Moor and Larry Fliegel

Protein Kinase-mediated Regulation of the Na⁺/H⁺ Exchanger in the Rat Myocardium by Mitogen-activated Protein Kinase-dependent Pathways
J. Biol. Chem. 1999 274: 22985-22992. [Abstract] [Full Text] [PDF]  

Valeria Golovanevsky and Baruch I. Kanner

The Reactivity of the -Aminobutyric Acid Transporter GAT-1 toward Sulfhydryl Reagents Is Conformationally Sensitive. IDENTIFICATION OF A MAJOR TARGET RESIDUE
J. Biol. Chem. 1999 274: 23020-23026. [Abstract] [Full Text] [PDF]  

Takahiro Iwamoto, Akira Uehara, Tomoe Y. Nakamura, Issei Imanaga, and Munekazu Shigekawa

Chimeric Analysis of Na⁺/Ca²⁺ Exchangers NCX1 and NCX3 Reveals Structural Domains Important for Differential Sensitivity to External Ni²⁺ or Li⁺
J. Biol. Chem. 1999 274: 23094-23102. [Abstract] [Full Text] [PDF]  

Bruce S. Kristal and Abraham M. Brown

Apoptogenic Ganglioside GD3 Directly Induces the Mitochondrial Permeability Transition
J. Biol. Chem. 1999 274: 23169-23175. [Abstract] [Full Text] [PDF]  

Wieslawa Jarmuszkiewicz, Claudine M. Sluse-Goffart, Lilla Hryniewiecka, and Francis E. Sluse

Identification and Characterization of a Protozoan Uncoupling Protein in Acanthamoeba castellanii
J. Biol. Chem. 1999 274: 23198-23202. [Abstract] [Full Text] [PDF]  

Yoshihiro Narusaka, Mari Narusaka, Kimiyuki Satoh, and Hirokazu Kobayashi

In Vitro Random Mutagenesis of the D1 Protein of the Photosystem II Reaction Center Confers Phototolerance on the Cyanobacterium Synechocystis sp. PCC 6803
J. Biol. Chem. 1999 274: 23270-23275. [Abstract] [Full Text] [PDF]  

Song Lin, Dong Cheng, Ming-Sun Liu, Jun Chen, and Ta-Yuan Chang

Human Acyl-CoA:Cholesterol Acyltransferase-1 in the Endoplasmic Reticulum Contains Seven Transmembrane Domains
J. Biol. Chem. 1999 274: 23276-23285. [Abstract] [Full Text] [PDF]  

Nicolas Fischer, Pierre Sétif, and Jean-David Rochaix

Site-directed Mutagenesis of the PsaC Subunit of Photosystem I. F_B IS THE CLUSTER INTERACTING WITH SOLUBLE FERREDOXIN
J. Biol. Chem. 1999 274: 23333-23340. [Abstract] [Full Text] [PDF]  

Juan M. Falcón-Pérez, María J. Mazón, Jesús Molano, and Pilar Eraso

Functional Domain Analysis of the Yeast ABC Transporter Ycf1p by Site-directed Mutagenesis
J. Biol. Chem. 1999 274: 23584-23590. [Abstract] [Full Text] [PDF]  

Toshiki Nakai, Aya Yamasaki, Masao Sakaguchi, Kenji Kosaka, Katsuyoshi Mihara, Yoshihiro Amaya, and Satoshi Miura

Membrane Topology of Alzheimer's Disease-related Presenilin 1. EVIDENCE FOR THE EXISTENCE OF A MOLECULAR SPECIES WITH A SEVEN MEMBRANE-SPANNING AND ONE MEMBRANE-EMBEDDED STRUCTURE
J. Biol. Chem. 1999 274: 23647-23658. [Abstract] [Full Text] [PDF]  

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Masayoshi Iizuka and Bruce Stillman

Histone Acetyltransferase HBO1 Interacts with the ORC1 Subunit of the Human Initiator Protein
J. Biol. Chem. 1999 274: 23027-23034. [Abstract] [Full Text] [PDF]  

David A. Rubin, Per Hellman, Leonard I. Zon, Craig J. Lobb, Clemens Bergwitz, and Harald Jüppner

A G Protein-coupled Receptor from Zebrafish Is Activated by Human Parathyroid Hormone and Not by Human or Teleost Parathyroid Hormone-related Peptide. IMPLICATIONS FOR THE EVOLUTIONARY CONSERVATION OF CALCIUM-REGULATING PEPTIDE HORMONES
J. Biol. Chem. 1999 274: 23035-23042. [Abstract] [Full Text] [PDF]  

Chien-Yuan Kao, Akihide Tanimoto, Nobuyuki Arima, Yasuyuki Sasaguri, and R. Padmanabhan

Transactivation of the Human cdc2 Promoter by Adenovirus E1A. E1A INDUCES THE EXPRESSION AND ASSEMBLY OF A HETEROMERIC COMPLEX CONSISTING OF THE CCAAT BOX BINDING FACTOR, CBF/NF-Y, AND A 110-kDa DNA-BINDING PROTEIN
J. Biol. Chem. 1999 274: 23043-23051. [Abstract] [Full Text] [PDF]  

Martin Klingenspor, Ping Xu, Robert D. Cohen, Carrie Welch, and Karen Reue

Altered Gene Expression Pattern in the Fatty Liver Dystrophy Mouse Reveals Impaired Insulin-mediated Cytoskeleton Dynamics
J. Biol. Chem. 1999 274: 23078-23084. [Abstract] [Full Text] [PDF]  

Cyril Couturier, Arthur Brouillet, Cécile Couriaud, Kamen Koumanov, Gilbert Béréziat, and Marise Andréani

Interleukin 1 Induces Type II-secreted Phospholipase A₂ Gene in Vascular Smooth Muscle Cells by a Nuclear Factor B and Peroxisome Proliferator-activated Receptor-mediated Process
J. Biol. Chem. 1999 274: 23085-23093. [Abstract] [Full Text] [PDF]  

Robert J. Denver, Lydia Ouellet, Denis Furling, Akira Kobayashi, Yoshiaki Fujii-Kuriyama, and Jack Puymirat

Basic Transcription Element-binding Protein (BTEB) Is a Thyroid Hormone-regulated Gene in the Developing Central Nervous System. EVIDENCE FOR A ROLE IN NEURITE OUTGROWTH
J. Biol. Chem. 1999 274: 23128-23134. [Abstract] [Full Text] [PDF]  

Chaitanya S. Bangur, Silviu L. Faitar, Jason P. Folster, and Alfred S. Ponticelli

An Interaction between the N-terminal Region and the Core Domain of Yeast TFIIB Promotes the Formation of TATA-binding Protein-TFIIB-DNA Complexes
J. Biol. Chem. 1999 274: 23203-23209. [Abstract] [Full Text] [PDF]  

Sally-Anne Stephenson, Karen Verity, Linda K. Ashworth, and Judith A. Clements

Localization of a New Prostate-specific Antigen-related Serine Protease Gene, KLK4, Is Evidence for an Expanded Human Kallikrein Gene Family Cluster on Chromosome 19q13.3-13.4
J. Biol. Chem. 1999 274: 23210-23214. [Abstract] [Full Text] [PDF]  

Zheng Pan, Christopher J. Hetherington, and Dong-Er Zhang

CCAAT/Enhancer-binding Protein Activates the CD14 Promoter and Mediates Transforming Growth Factor  Signaling in Monocyte Development
J. Biol. Chem. 1999 274: 23242-23248. [Abstract] [Full Text] [PDF]  

Ilgar Abbaszade, Rui-Qin Liu, Fude Yang, Stuart A. Rosenfeld, O. Harold Ross, John R. Link, Dawn M. Ellis, Micky D. Tortorella, Michael A. Pratta, Jeannine M. Hollis, Richard Wynn, Jodie L. Duke, Henry J. George, Milton C. Hillman Jr., Kathleen Murphy, Barbara H. Wiswall, Robert A. Copeland, Carl P. Decicco, Robert Bruckner, Hideaki Nagase, Yoshifumi Itoh, Robert C. Newton, Ronald L. Magolda, James M. Trzaskos, Gregory F. Hollis, Elizabeth C. Arner, and Timothy C. Burn

Cloning and Characterization of ADAMTS11, an Aggrecanase from the ADAMTS Family
J. Biol. Chem. 1999 274: 23443-23450. [Abstract] [Full Text] [PDF]  

Volkher Scharnhorst, Patrick Dekker, Alex J. van der Eb, and Aart G. Jochemsen

Internal Translation Initiation Generates Novel WT1 Protein Isoforms with Distinct Biological Properties
J. Biol. Chem. 1999 274: 23456-23462. [Abstract] [Full Text] [PDF]  

John P. Jakupciak and Robert D. Wells

Genetic Instabilities in (CTG·CAG) Repeats Occur by Recombination
J. Biol. Chem. 1999 274: 23468-23479. [Abstract] [Full Text] [PDF]  

Shwu Yuan Wu, Mary C. Thomas, Samuel Y. Hou, Varsha Likhite, and Cheng Ming Chiang

Isolation of Mouse TFIID and Functional Characterization of TBP and TFIID in Mediating Estrogen Receptor and Chromatin Transcription
J. Biol. Chem. 1999 274: 23480-23490. [Abstract] [Full Text] [PDF]  

Melissa Holmes, Jeremy Turner, Archa Fox, Orin Chisholm, Merlin Crossley, and Beng Chong

hFOG-2, a Novel Zinc Finger Protein, Binds the Co-repressor mCtBP2 and Modulates GATA-mediated Activation
J. Biol. Chem. 1999 274: 23491-23498. [Abstract] [Full Text] [PDF]  

Sudsanguan Chusacultanachai, Kevin A. Glenn, Adrian O. Rodriguez, Erik K. Read, Jeffrey F. Gardner, Benita S. Katzenellenbogen, and David J. Shapiro

Analysis of Estrogen Response Element Binding by Genetically Selected Steroid Receptor DNA Binding Domain Mutants Exhibiting Altered Specificity and Enhanced Affinity
J. Biol. Chem. 1999 274: 23591-23598. [Abstract] [Full Text] [PDF]  

Thomas E. Wilson and Michael R. Lieber

Efficient Processing of DNA Ends during Yeast Nonhomologous End Joining. EVIDENCE FOR A DNA POLYMERASE  (POL4)-DEPENDENT PATHWAY
J. Biol. Chem. 1999 274: 23599-23609. [Abstract] [Full Text] [PDF]  

Hsien-Ching Liu, Jen-Tieng Shen, Lance B. Augustin, Jane L. Ko, and Horace H. Loh

Transcriptional Regulation of Mouse -Opioid Receptor Gene
J. Biol. Chem. 1999 274: 23617-23626. [Abstract] [Full Text] [PDF]  

Indranil Biswas, Changill Ban, Karen G. Fleming, Jun Qin, Jeffrey W. Lary, David A. Yphantis, Wei Yang, and Peggy Hsieh

Oligomerization of a MutS Mismatch Repair Protein from Thermus aquaticus
J. Biol. Chem. 1999 274: 23673-23678. [Abstract] [Full Text] [PDF]  

Protein Chemistry and Structure

Tomohiro Yamakura, S. John Mihic, and R. Adron Harris

Amino Acid Volume and Hydropathy of a Transmembrane Site Determine Glycine and Anesthetic Sensitivity of Glycine Receptors
J. Biol. Chem. 1999 274: 23006-23012. [Abstract] [Full Text] [PDF]  

Hideyuki Miyatake, Masahiro Mukai, Shin-ichi Adachi, Hiro Nakamura, Koji Tamura, Tetsutaro Iizuka, Yoshitsugu Shiro, Richard W. Strange, and S. Samar Hasnain

Iron Coordination Structures of Oxygen Sensor FixL Characterized by Fe K-edge Extended X-ray Absorption Fine Structure and Resonance Raman Spectroscopy
J. Biol. Chem. 1999 274: 23176-23184. [Abstract] [Full Text] [PDF]  

Sandrine Silvente-Poirot, Chantal Escrieut, Céline Galès, Jean-Alain Fehrentz, Achim Escherich, Stephen A. Wank, Jean Martinez, Luis Moroder, Bernard Maigret, Michelle Bouisson, Nicole Vaysse, and Daniel Fourmy

Evidence for a Direct Interaction between the Penultimate Aspartic Acid of Cholecystokinin and Histidine 207, Located in the Second Extracellular Loop of the Cholecystokinin B Receptor
J. Biol. Chem. 1999 274: 23191-23197. [Abstract] [Full Text] [PDF]  

Robert A. Cherny, Jacinta T. Legg, Catriona A. McLean, David P. Fairlie, Xudong Huang, Craig S. Atwood, Konrad Beyreuther, Rudolph E. Tanzi, Colin L. Masters, and Ashley I. Bush

Aqueous Dissolution of Alzheimer's Disease A Amyloid Deposits by Biometal Depletion
J. Biol. Chem. 1999 274: 23223-23228. [Abstract] [Full Text] [PDF]  

Sushma Nagpal, Vibha Gupta, Kanwal J. Kaur, and Dinakar M. Salunke

Structure-Function Analysis of Tritrypticin, an Antibacterial Peptide of Innate Immune Origin
J. Biol. Chem. 1999 274: 23296-23304. [Abstract] [Full Text] [PDF]  

Scott W. Rowlinson, Brenda C. Crews, Cheryl A. Lanzo, and Lawrence J. Marnett

The Binding of Arachidonic Acid in the Cyclooxygenase Active Site of Mouse Prostaglandin Endoperoxide Synthase-2 (COX-2). A PUTATIVE L-SHAPED BINDING CONFORMATION UTILIZING THE TOP CHANNEL REGION
J. Biol. Chem. 1999 274: 23305-23310. [Abstract] [Full Text] [PDF]  

Sylvie Phalipou, René Seyer, Nathalie Cotte, Christophe Breton, Claude Barberis, Marcel Hibert, and Bernard Mouillac

Docking of Linear Peptide Antagonists into the Human V_1a Vasopressin Receptor. IDENTIFICATION OF BINDING DOMAINS BY PHOTOAFFINITY LABELING
J. Biol. Chem. 1999 274: 23316-23327. [Abstract] [Full Text] [PDF]  

Jackie B. M. Janosi, Paul A. Ramsland, Margaret R. Mott, Sue M. Firth, Robert C. Baxter, and Patric J. D. Delhanty

The Acid-labile Subunit of the Serum Insulin-like Growth Factor-binding Protein Complexes. STRUCTURAL DETERMINATION BY MOLECULAR MODELING AND ELECTRON MICROSCOPY
J. Biol. Chem. 1999 274: 23328-23332. [Abstract] [Full Text] [PDF]  

Francisca Vázquez, Gregg Hastings, Maria-Asunción Ortega, Timothy F. Lane, Sarah Oikemus, Michelle Lombardo, and M. Luisa Iruela-Arispe

METH-1, a Human Ortholog of ADAMTS-1, and METH-2 Are Members of a New Family of Proteins with Angio-inhibitory Activity
J. Biol. Chem. 1999 274: 23349-23357. [Abstract] [Full Text] [PDF]  

Nick Loizos and Seth A. Darst

Mapping Interactions of Escherichia coli GreB with RNA Polymerase and Ternary Elongation Complexes
J. Biol. Chem. 1999 274: 23378-23386. [Abstract] [Full Text] [PDF]  

Yu Liu, William W. Cruikshank, Terence O'Loughlin, Phillip O'Reilly, David M. Center, and Hardy Kornfeld

Identification of a CD4 Domain Required for Interleukin-16 Binding and Lymphocyte Activation
J. Biol. Chem. 1999 274: 23387-23395. [Abstract] [Full Text] [PDF]  

Tiina Salminen, Minna Varis, Tommi Nyrönen, Marjo Pihlavisto, Anna-Marja Hoffrén, Tuomas Lönnberg, Anne Marjamäki, Heini Frang, Juha-Matti Savola, Mika Scheinin, and Mark S. Johnson

Three-dimensional Models of _2A-Adrenergic Receptor Complexes Provide a Structural Explanation for Ligand Binding
J. Biol. Chem. 1999 274: 23405-23413. [Abstract] [Full Text] [PDF]  

Richard J. Pleass, James I. Dunlop, Catherine M. Anderson, and Jenny M. Woof

Identification of Residues in the CH2/CH3 Domain Interface of IgA Essential for Interaction with the Human Fc Receptor (FcR) CD89
J. Biol. Chem. 1999 274: 23508-23514. [Abstract] [Full Text] [PDF]  

Christopher Sinclair, Christoph Borchers, Carol Parker, Kenneth Tomer, Harry Charbonneau, and Sandra Rossie

The Tetratricopeptide Repeat Domain and a C-terminal Region Control the Activity of Ser/Thr Protein Phosphatase 5
J. Biol. Chem. 1999 274: 23666-23672. [Abstract] [Full Text] [PDF]  

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