JBC -- Table of Contents (Jan 22 1999, 274, (4))

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Enzymology:

Deborah A. Enke, Philipp Kaldis, Jennifer K. Holmes, and Mark J. Solomon: The CDK-activating Kinase (Cak1p) from Budding Yeast Has an Unusual ATP-binding Pocket
J. Biol. Chem. 1999 274: 1949-1956. First Published ; doi:10.1074/jbc.274.4.1949 [Abstract] [Full Text] [PDF]

Zheng Wei and Stuart J. Swiedler: Functional Analysis of Conserved Cysteines in Heparan Sulfate N-Deacetylase-N-sulfotransferases
J. Biol. Chem. 1999 274: 1966-1970. First Published ; doi:10.1074/jbc.274.4.1966 [Abstract] [Full Text] [PDF]

Gerard Bannenberg, Sven-Erik Dahlén, Marjanka Luijerink, Gerd Lundqvist, and Ralf Morgenstern: Leukotriene C₄ Is a Tight-binding Inhibitor of Microsomal Glutathione Transferase-1. EFFECTS OF LEUKOTRIENE PATHWAY MODIFIERS
J. Biol. Chem. 1999 274: 1994-1999. First Published ; doi:10.1074/jbc.274.4.1994 [Abstract] [Full Text] [PDF]

Robert B. Calder, Robin S. B. Williams, Gayathri Ramaswamy, Charles O. Rock, Eddie Campbell, Shiela E. Unkles, James R. Kinghorn, and Suzanne Jackowski: Cloning and Characterization of a Eukaryotic Pantothenate Kinase Gene (panK) from Aspergillus nidulans
J. Biol. Chem. 1999 274: 2014-2020. First Published ; doi:10.1074/jbc.274.4.2014 [Abstract] [Full Text] [PDF]

Irina A. Pikuleva, Carolyn Cao, and Michael R. Waterman: An Additional Electrostatic Interaction between Adrenodoxin and P450c27 (CYP27A1) Results in Tighter Binding Than between Adrenodoxin and P450scc (CYP11A1)
J. Biol. Chem. 1999 274: 2045-2052. First Published ; doi:10.1074/jbc.274.4.2045 [Abstract] [Full Text] [PDF]

Yuh-Ru Chen, Frank W. Larimer, Engin H. Serpersu, and Fred C. Hartman: Identification of a Catalytic Aspartyl Residue of D-Ribulose 5-Phosphate 3-Epimerase by Site-directed Mutagenesis
J. Biol. Chem. 1999 274: 2132-2136. First Published ; doi:10.1074/jbc.274.4.2132 [Abstract] [Full Text] [PDF]

Shi Du Yan, Yigong Shi, Aiping Zhu, Jin Fu, Huaijie Zhu, Yucui Zhu, Lenneen Gibson, Eric Stern, Kate Collison, Futwan Al-Mohanna, Satoshi Ogawa, Alex Roher, Steven G. Clarke, and David M. Stern: Role of ERAB/L-3-Hydroxyacyl-coenzyme A Dehydrogenase Type II Activity in A $beta$ -induced Cytotoxicity
J. Biol. Chem. 1999 274: 2145-2156. First Published ; doi:10.1074/jbc.274.4.2145 [Abstract] [Full Text] [PDF]

Hiroyuki Mizuguchi, Paul F. Cook, Chia-Hui Tai, Charles A. Hasemann, and Kosaku Uyeda: Reaction Mechanism of Fructose-2,6-bisphosphatase. A MUTATION OF NUCLEOPHILIC CATALYST, HISTIDINE 256, INDUCES AN ALTERATION IN THE REACTION PATHWAY
J. Biol. Chem. 1999 274: 2166-2175. First Published ; doi:10.1074/jbc.274.4.2166 [Abstract] [Full Text] [PDF]

Mi H. Yuen, Hiroyuki Mizuguchi, Yong-Hwan Lee, Paul F. Cook, Kosaku Uyeda, and Charles A. Hasemann: Crystal Structure of the H256A Mutant of Rat Testis Fructose-6-phosphate,2-kinase/Fructose-2,6-bisphosphatase. FRUCTOSE 6-PHOSPHATE IN THE ACTIVE SITE LEADS TO MECHANISMS FOR BOTH MUTANT AND WILD TYPE BISPHOSPHATASE ACTIVITIES
J. Biol. Chem. 1999 274: 2176-2184. First Published ; doi:10.1074/jbc.274.4.2176 [Abstract] [Full Text] [PDF]

Shinya Oue, Akihiro Okamoto, Takato Yano, and Hiroyuki Kagamiyama: Redesigning the Substrate Specificity of an Enzyme by Cumulative Effects of the Mutations of Non-active Site Residues
J. Biol. Chem. 1999 274: 2344-2349. First Published ; doi:10.1074/jbc.274.4.2344 [Abstract] [Full Text] [PDF]

Communications:

Ichiro Kato, Yasuhiko Yamamoto, Miki Fujimura, Naoya Noguchi, Shin Takasawa, and Hiroshi Okamoto: CD38 Disruption Impairs Glucose-induced Increases in Cyclic ADP-ribose, [Ca²⁺]_i, and Insulin Secretion
J. Biol. Chem. 1999 274: 1869-1872. First Published ; doi:10.1074/jbc.274.4.1869 [Abstract] [Full Text] [PDF]

Geert M. J. Ramakers, Dan D. Gerendasy, and Pierre N. E. de Graan: Substrate Phosphorylation in the Protein Kinase C $gamma$ Knockout Mouse
J. Biol. Chem. 1999 274: 1873-1874. First Published ; doi:10.1074/jbc.274.4.1873 [Abstract] [Full Text] [PDF]

Lisa K. Naeger, Judi McKinney, Anupama Salvekar, and Timothy Hoey: Identification of a STAT4 Binding Site in the Interleukin-12 Receptor Required for Signaling
J. Biol. Chem. 1999 274: 1875-1878. First Published ; doi:10.1074/jbc.274.4.1875 [Abstract] [Full Text] [PDF]

Raj Wadgaonkar, Kathleen M. Phelps, Zaffar Haque, Amy J. Williams, Eric S. Silverman, and Tucker Collins: CREB-binding Protein Is a Nuclear Integrator of Nuclear Factor- $kappa$ B and p53 Signaling
J. Biol. Chem. 1999 274: 1879-1882. First Published ; doi:10.1074/jbc.274.4.1879 [Abstract] [Full Text] [PDF]

Zhi-Min Yuan, Yinyin Huang, Takatoshi Ishiko, Shuji Nakada, Taiju Utsugisawa, Hisashi Shioya, Yukari Utsugisawa, Kazunari Yokoyama, Ralph Weichselbaum, Yang Shi, and Donald Kufe: Role for p300 in Stabilization of p53 in the Response to DNA Damage
J. Biol. Chem. 1999 274: 1883-1886. First Published ; doi:10.1074/jbc.274.4.1883 [Abstract] [Full Text] [PDF]

Tomoyasu Aizawa, Naoki Fujitani, Yoichi Hayakawa, Atsushi Ohnishi, Tadayasu Ohkubo, Yasuhiro Kumaki, Keiichi Kawano, Kunio Hikichi, and Katsutoshi Nitta: Solution Structure of an Insect Growth Factor, Growth-blocking Peptide
J. Biol. Chem. 1999 274: 1887-1890. First Published ; doi:10.1074/jbc.274.4.1887 [Abstract] [Full Text] [PDF]

Carbohydrates, Lipids, and Other Natural Products:

Koji Uchida, Mihoko Shiraishi, Yuko Naito, Yasuyoshi Torii, Yoshimasa Nakamura, and Toshihiko Osawa: Activation of Stress Signaling Pathways by the End Product of Lipid Peroxidation. 4-HYDROXY-2-NONENAL IS A POTENTIAL INDUCER OF INTRACELLULAR PEROXIDE PRODUCTION
J. Biol. Chem. 1999 274: 2234-2242. First Published ; doi:10.1074/jbc.274.4.2234 [Abstract] [Full Text] [PDF]

Takeshi Arai, Nan Wang, Mikhail Bezouevski, Carrie Welch, and Alan R. Tall: Decreased Atherosclerosis in Heterozygous Low Density Lipoprotein Receptor-deficient Mice Expressing the Scavenger Receptor BI Transgene
J. Biol. Chem. 1999 274: 2366-2371. First Published ; doi:10.1074/jbc.274.4.2366 [Abstract] [Full Text] [PDF]

Shinobu Yamauchi, Yukie Hirahara, Hiroaki Usui, Yoshiko Takeda, Megumi Hoshino, Masakazu Fukuta, James H. Kimura, and Osami Habuchi: Purification and Characterization of Chondroitin 4-Sulfotransferase from the Culture Medium of a Rat Chondrosarcoma Cell Line
J. Biol. Chem. 1999 274: 2456-2463. First Published ; doi:10.1074/jbc.274.4.2456 [Abstract] [Full Text] [PDF]

Rajeswari M. H. Ravindranath, Janet Moradian-Oldak, and Alan G. Fincham: Tyrosyl Motif in Amelogenins Binds N-Acetyl-D-glucosamine
J. Biol. Chem. 1999 274: 2464-2471. First Published ; doi:10.1074/jbc.274.4.2464 [Abstract] [Full Text] [PDF]

Cell Biology and Metabolism:

Abdelhafid Saci, Sabine Pain, Francine Rendu, and Christilla Bachelot-Loza: Fc Receptor-mediated Platelet Activation Is Dependent on Phosphatidylinositol 3-Kinase Activation and Involves p120^cbl
J. Biol. Chem. 1999 274: 1898-1904. First Published ; doi:10.1074/jbc.274.4.1898 [Abstract] [Full Text] [PDF]

Kenneth M. Lerea, Kenneth P. Cordero, Kjell S. Sakariassen, Rita I. Kirk, and Victor A. Fried: Phosphorylation Sites in the Integrin $beta$ ₃ Cytoplasmic Domain in Intact Platelets
J. Biol. Chem. 1999 274: 1914-1919. First Published ; doi:10.1074/jbc.274.4.1914 [Abstract] [Full Text] [PDF]

Alexander V. Chibalin, Goichi Ogimoto, Carlos H. Pedemonte, Thomas A. Pressley, Adrian I. Katz, Eric Féraille, Per-Olof Berggren, and Alejandro M. Bertorello: Dopamine-induced Endocytosis of Na⁺,K⁺-ATPase Is Initiated by Phosphorylation of Ser-18 in the Rat $alpha$ Subunit and Is Responsible for the Decreased Activity in Epithelial Cells
J. Biol. Chem. 1999 274: 1920-1927. First Published ; doi:10.1074/jbc.274.4.1920 [Abstract] [Full Text] [PDF]

Fabiana Antognoni, Stefano Del Duca, Aiko Kuraishi, Eri Kawabe, Tomomi Fukuchi-Shimogori, Keiko Kashiwagi, and Kazuei Igarashi: Transcriptional Inhibition of the Operon for the Spermidine Uptake System by the Substrate-binding Protein PotD
J. Biol. Chem. 1999 274: 1942-1948. First Published ; doi:10.1074/jbc.274.4.1942 [Abstract] [Full Text] [PDF]

Junji Yamauchi, Yoshito Kaziro, and Hiroshi Itoh: Differential Regulation of Mitogen-activated Protein Kinase Kinase 4 (MKK4) and 7 (MKK7) by Signaling from G Protein $beta$ $gamma$ Subunit in Human Embryonal Kidney 293 Cells
J. Biol. Chem. 1999 274: 1957-1965. First Published ; doi:10.1074/jbc.274.4.1957 [Abstract] [Full Text] [PDF]

Shigeru Owada, Olof Larsson, Per Arkhammar, Adrian I. Katz, Alexander V. Chibalin, Per-Olof Berggren, and Alejandro M. Bertorello: Glucose Decreases Na⁺,K⁺-ATPase Activity in Pancreatic $beta$ -Cells. AN EFFECT MEDIATED VIA Ca²⁺-INDEPENDENT PHOSPHOLIPASE A₂ AND PROTEIN KINASE CDEPENDENT PHOSPHORYLATION OF THE $alpha$ -SUBUNIT
J. Biol. Chem. 1999 274: 2000-2008. First Published ; doi:10.1074/jbc.274.4.2000 [Abstract] [Full Text] [PDF]

Marta Casado, Virginie S. Vallet, Axel Kahn, and Sophie Vaulont: Essential Role in Vivo of Upstream Stimulatory Factors for a Normal Dietary Response of the Fatty Acid Synthase Gene in the Liver
J. Biol. Chem. 1999 274: 2009-2013. First Published ; doi:10.1074/jbc.274.4.2009 [Abstract] [Full Text] [PDF]

Kristin L. Gillotte, Mohamed Zaiou, Sissel Lund-Katz, G. M. Anantharamaiah, Paul Holvoet, Ann Dhoest, Mayakonda N. Palgunachari, Jere P. Segrest, Karl H. Weisgraber, George H. Rothblat, and Michael C. Phillips: Apolipoprotein-mediated Plasma Membrane Microsolubilization. ROLE OF LIPID AFFINITY AND MEMBRANE PENETRATION IN THE EFFLUX OF CELLULAR CHOLESTEROL AND PHOSPHOLIPID
J. Biol. Chem. 1999 274: 2021-2028. First Published ; doi:10.1074/jbc.274.4.2021 [Abstract] [Full Text] [PDF]

Peter Scheiffele, Anton Rietveld, Thomas Wilk, and Kai Simons: Influenza Viruses Select Ordered Lipid Domains during Budding from the Plasma Membrane
J. Biol. Chem. 1999 274: 2038-2044. First Published ; doi:10.1074/jbc.274.4.2038 [Abstract] [Full Text] [PDF]

John F. O'Rourke, Ya-Min Tian, Peter J. Ratcliffe, and Christopher W. Pugh: Oxygen-regulated and Transactivating Domains in Endothelial PAS Protein 1: Comparison with Hypoxia-inducible Factor-1 $alpha$
J. Biol. Chem. 1999 274: 2060-2071. First Published ; doi:10.1074/jbc.274.4.2060 [Abstract] [Full Text] [PDF]

Dai-Wu Seol and Timothy R. Billiar: A Caspase-9 Variant Missing the Catalytic Site Is an Endogenous Inhibitor of Apoptosis
J. Biol. Chem. 1999 274: 2072-2076. First Published ; doi:10.1074/jbc.274.4.2072 [Abstract] [Full Text] [PDF]

Seija Hunter, Elizabeth A. Burton, Steven C. Wu, and Steven M. Anderson: Fyn Associates with Cbl and Phosphorylates Tyrosine 731 in Cbl, A Binding Site for Phosphatidylinositol 3-Kinase
J. Biol. Chem. 1999 274: 2097-2106. First Published ; doi:10.1074/jbc.274.4.2097 [Abstract] [Full Text] [PDF]

Kathryn J. Ivins, Jonathan K. Ivins, Jason P. Sharp, and Carl W. Cotman: Multiple Pathways of Apoptosis in PC12 Cells. CrmA INHIBITS APOPTOSIS INDUCED BY $beta$ -AMYLOID
J. Biol. Chem. 1999 274: 2107-2112. First Published ; doi:10.1074/jbc.274.4.2107 [Abstract] [Full Text] [PDF]

Zhengbin Yao, Guisheng Zhou, Xuhong Sunny Wang, Amy Brown, Katrina Diener, Hong Gan, and Tse-Hua Tan: A Novel Human STE20-related Protein Kinase, HGK, That Specifically Activates the c-Jun N-terminal Kinase Signaling Pathway
J. Biol. Chem. 1999 274: 2118-2125. First Published ; doi:10.1074/jbc.274.4.2118 [Abstract] [Full Text] [PDF]

Tianyan Gao, Andy J. Chien, and M. Marlene Hosey: Complexes of the $alpha$ _1C and $beta$ Subunits Generate the Necessary Signal for Membrane Targeting of Class C L-type Calcium Channels
J. Biol. Chem. 1999 274: 2137-2144. First Published ; doi:10.1074/jbc.274.4.2137 [Abstract] [Full Text] [PDF]

Sanjeev Gupta, Pankaj Rajvanshi, Rana P. Sokhi, Shilpa Vaidya, Adil N. Irani, and Giridhar R. Gorla: Position-specific Gene Expression in the Liver Lobule Is Directed by the Microenvironment and Not by the Previous Cell Differentiation State
J. Biol. Chem. 1999 274: 2157-2165. First Published ; doi:10.1074/jbc.274.4.2157 [Abstract] [Full Text] [PDF]

Francisca Vázquez, Juan Carlos Rodríguez-Manzaneque, John P. Lydon, Dean P. Edwards, Bert W. O'Malley, and M. Luisa Iruela-Arispe: Progesterone Regulates Proliferation of Endothelial Cells
J. Biol. Chem. 1999 274: 2185-2192. First Published ; doi:10.1074/jbc.274.4.2185 [Abstract] [Full Text] [PDF]

Ena Orzech, Karni Schlessinger, Aryeh Weiss, Curtis T. Okamoto, and Benjamin Aroeti: Interactions of the AP-1 Golgi Adaptor with the Polymeric Immunoglobulin Receptor and Their Possible Role in Mediating Brefeldin A-sensitive Basolateral Targeting from the trans-Golgi Network
J. Biol. Chem. 1999 274: 2201-2215. First Published ; doi:10.1074/jbc.274.4.2201 [Abstract] [Full Text] [PDF]

JoAnn Trejo and Shaun R. Coughlin: The Cytoplasmic Tails of Protease-activated Receptor-1 and Substance P Receptor Specify Sorting to Lysosomes versus Recycling
J. Biol. Chem. 1999 274: 2216-2224. First Published ; doi:10.1074/jbc.274.4.2216 [Abstract] [Full Text] [PDF]

Deborah M. Finucane, Ella Bossy-Wetzel, Nigel J. Waterhouse, Thomas G. Cotter, and Douglas R. Green: Bax-induced Caspase Activation and Apoptosis via Cytochrome c Release from Mitochondria Is Inhibitable by Bcl-xL
J. Biol. Chem. 1999 274: 2225-2233. First Published ; doi:10.1074/jbc.274.4.2225 [Abstract] [Full Text] [PDF]

Susumu Tomita, Toshinori Ozaki, Hidenori Taru, Shinobu Oguchi, Shizu Takeda, Yoshimasa Yagi, Shigeru Sakiyama, Yutaka Kirino, and Toshiharu Suzuki: Interaction of a Neuron-specific Protein Containing PDZ Domains with Alzheimer's Amyloid Precursor Protein
J. Biol. Chem. 1999 274: 2243-2254. First Published ; doi:10.1074/jbc.274.4.2243 [Abstract] [Full Text] [PDF]

Masaru Araki, Hiroki Nanri, Kuniaki Ejima, Yoshinobu Murasato, Toshiyuki Fujiwara, Yasuhide Nakashima, and Masaharu Ikeda: Antioxidant Function of the Mitochondrial Protein SP-22 in the Cardiovascular System
J. Biol. Chem. 1999 274: 2271-2278. First Published ; doi:10.1074/jbc.274.4.2271 [Abstract] [Full Text] [PDF]

Judith A. Glaven, Ian Whitehead, Shubha Bagrodia, Robert Kay, and Richard A. Cerione: The Dbl-related Protein, Lfc, Localizes to Microtubules and Mediates the Activation of Rac Signaling Pathways in Cells
J. Biol. Chem. 1999 274: 2279-2285. First Published ; doi:10.1074/jbc.274.4.2279 [Abstract] [Full Text] [PDF]

Yoshiharu Takayama, Sakae Tanaka, Katsuya Nagai, and Masato Okada: Adenovirus-mediated Overexpression of C-terminal Src Kinase (Csk) in Type I Astrocytes Interferes with Cell Spreading and Attachment to Fibronectin. CORRELATION WITH TYROSINE PHOSPHORYLATIONS OF PAXILLIN AND FAK
J. Biol. Chem. 1999 274: 2291-2297. First Published ; doi:10.1074/jbc.274.4.2291 [Abstract] [Full Text] [PDF]

Juan Wang and Kathleen M. Giacomini: Serine 318 Is Essential for the Pyrimidine Selectivity of the N2 Na⁺-Nucleoside Transporter
J. Biol. Chem. 1999 274: 2298-2302. First Published ; doi:10.1074/jbc.274.4.2298 [Abstract] [Full Text] [PDF]

Yoshinori Doi, Masahiko Itoh, Shigenobu Yonemura, Satoru Ishihara, Hiroshi Takano, Tetsuo Noda, Shoichiro Tsukita, and Sachiko Tsukita: Normal Development of Mice and Unimpaired Cell Adhesion/Cell Motility/Actin-based Cytoskeleton without Compensatory Up-regulation of Ezrin or Radixin in Moesin Gene Knockout
J. Biol. Chem. 1999 274: 2315-2321. First Published ; doi:10.1074/jbc.274.4.2315 [Abstract] [Full Text] [PDF]

Shankar S. Iyer and David J. Kusner: Association of Phospholipase D Activity with the Detergent-insoluble Cytoskeleton of U937 Promonocytic Leukocytes
J. Biol. Chem. 1999 274: 2350-2359. First Published ; doi:10.1074/jbc.274.4.2350 [Abstract] [Full Text] [PDF]

Jacob B. Hansen, Rasmus K. Petersen, Berit M. Larsen, Jirina Bartkova, Jan Alsner, and Karsten Kristiansen: Activation of Peroxisome Proliferator-activated Receptor $gamma$ Bypasses the Function of the Retinoblastoma Protein in Adipocyte Differentiation
J. Biol. Chem. 1999 274: 2386-2393. First Published ; doi:10.1074/jbc.274.4.2386 [Abstract] [Full Text] [PDF]

Anne Roobol, Zeina P. Sahyoun, and Martin J. Carden: Selected Subunits of the Cytosolic Chaperonin Associate with Microtubules Assembled in Vitro
J. Biol. Chem. 1999 274: 2408-2415. First Published ; doi:10.1074/jbc.274.4.2408 [Abstract] [Full Text] [PDF]

Sudha Chaturvedi, Huilin Qi, David Coleman, Anna Rodriguez, Phyllis I. Hanson, Boris Striepen, David S. Roos, and Keith A. Joiner: Constitutive Calcium-independent Release of Toxoplasma gondii Dense Granules Occurs through the NSF/SNAP/SNARE/Rab Machinery
J. Biol. Chem. 1999 274: 2424-2431. First Published ; doi:10.1074/jbc.274.4.2424 [Abstract] [Full Text] [PDF]

Laura Ravanti, Jyrki Heino, Carlos López-Otín, and Veli-Matti Kähäri: Induction of Collagenase-3 (MMP-13) Expression in Human Skin Fibroblasts by Three-dimensional Collagen Is Mediated by p38 Mitogen-activated Protein Kinase
J. Biol. Chem. 1999 274: 2446-2455. First Published ; doi:10.1074/jbc.274.4.2446 [Abstract] [Full Text] [PDF]

Robert Flaumenhaft, Kevin Croce, Emy Chen, Bruce Furie, and Barbara C. Furie: Proteins of the Exocytotic Core Complex Mediate Platelet $alpha$ -Granule Secretion. ROLES OF VESICLE-ASSOCIATED MEMBRANE PROTEIN, SNAP-23, AND SYNTAXIN 4
J. Biol. Chem. 1999 274: 2492-2501. First Published ; doi:10.1074/jbc.274.4.2492 [Abstract] [Full Text] [PDF]

John J. Reiners, Jr. and Russell E. Clift: Aryl Hydrocarbon Receptor Regulation of Ceramide-induced Apoptosis in Murine Hepatoma 1c1c7 Cells. A FUNCTION INDEPENDENT OF ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR
J. Biol. Chem. 1999 274: 2502-2510. First Published ; doi:10.1074/jbc.274.4.2502 [Abstract] [Full Text] [PDF]

Brad Greenfield, Wei-Chun Wang, Hans Marquardt, Michael Piepkorn, Edith A. Wolff, Alejandro Aruffo, and Kelly L. Bennett: Characterization of the Heparan Sulfate and Chondroitin Sulfate Assembly Sites in CD44
J. Biol. Chem. 1999 274: 2511-2517. First Published ; doi:10.1074/jbc.274.4.2511 [Abstract] [Full Text] [PDF]

Edith A. Wolff, Brad Greenfield, Dennis D. Taub, William J. Murphy, Kelly L. Bennett, and Alejandro Aruffo: Generation of Artificial Proteoglycans Containing Glycosaminoglycan-modified CD44. DEMONSTRATION OF THE INTERACTION BETWEEN RANTES AND CHONDROITIN SULFATE
J. Biol. Chem. 1999 274: 2518-2524. First Published ; doi:10.1074/jbc.274.4.2518 [Abstract] [Full Text] [PDF]

Alan Nighorn, Kathryn A. Byrnes, and David B. Morton: Identification and Characterization of a Novel $beta$ Subunit of Soluble Guanylyl Cyclase That Is Active in the Absence of a Second Subunit and Is Relatively Insensitive to Nitric Oxide
J. Biol. Chem. 1999 274: 2525-2531. First Published ; doi:10.1074/jbc.274.4.2525 [Abstract] [Full Text] [PDF]

Matthew E. Kennedy, Jan Nemec, Shawn Corey, Kevin Wickman, and David E. Clapham: GIRK4 Confers Appropriate Processing and Cell Surface Localization to G-protein-gated Potassium Channels
J. Biol. Chem. 1999 274: 2571-2582. First Published ; doi:10.1074/jbc.274.4.2571 [Abstract] [Full Text] [PDF]

Membranes and Bioenergetics:

Salvatore J. Siciliano, Shawn E. Kuhmann, Youmin Weng, Navid Madani, Martin S. Springer, Janet E. Lineberger, Renee Danzeisen, Michael D. Miller, Michael P. Kavanaugh, Julie A. DeMartino, and David Kabat: A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1
J. Biol. Chem. 1999 274: 1905-1913. First Published ; doi:10.1074/jbc.274.4.1905 [Abstract] [Full Text] [PDF]

H. Bart van den Hazel, Harald Pichler, Maria Adelaide do Valle Matta, Erich Leitner, André Goffeau, and Günther Daum: PDR16 and PDR17, Two Homologous Genes of Saccharomyces cerevisiae, Affect Lipid Biosynthesis and Resistance to Multiple Drugs
J. Biol. Chem. 1999 274: 1934-1941. First Published ; doi:10.1074/jbc.274.4.1934 [Abstract] [Full Text] [PDF]

Detlef Thoenges, Evzen Amler, Thomas Eckert, and Wilhelm Schoner: Tight Binding of Bulky Fluorescent Derivatives of Adenosine to the Low Affinity E₂ATP Site Leads to Inhibition of Na⁺/K⁺-ATPase. ANALYSIS OF STRUCTURAL REQUIREMENTS OF FLUORESCENT ATP DERIVATIVES WITH A KOSHLAND-NÉMETHY-FILMER MODEL OF TWO INTERACTING ATP SITES
J. Biol. Chem. 1999 274: 1971-1978. First Published ; doi:10.1074/jbc.274.4.1971 [Abstract] [Full Text] [PDF]

Kazuya Matsumoto, Kenji Ebihara, Hideyuki Yamamoto, Hirotaka Tabuchi, Kohji Fukunaga, Michio Yasunami, Hiroaki Ohkubo, Motoaki Shichiri, and Eishichi Miyamoto: Cloning from Insulinoma Cells of Synapsin I Associated with Insulin Secretory Granules
J. Biol. Chem. 1999 274: 2053-2059. First Published ; doi:10.1074/jbc.274.4.2053 [Abstract] [Full Text] [PDF]

Seiko Kawano, Akinori Kuruma, Yoshiyuki Hirayama, and Masayasu Hiraoka: Anion Permeability and Conduction of Adenine Nucleotides Through a Chloride Channel in Cardiac Sarcoplasmic Reticulum
J. Biol. Chem. 1999 274: 2085-2092. First Published ; doi:10.1074/jbc.274.4.2085 [Abstract] [Full Text] [PDF]

Xing-Mai Jiang, Melinda Fitzgerald, Chris M. Grant, and Philip J. Hogg: Redox Control of Exofacial Protein Thiols/Disulfides by Protein Disulfide Isomerase
J. Biol. Chem. 1999 274: 2416-2423. First Published ; doi:10.1074/jbc.274.4.2416 [Abstract] [Full Text] [PDF]

Sheng-Bin Peng, Xinji Li, Bill P. Crider, Zhiming Zhou, Per Andersen, Sue Jean Tsai, Xiao-Song Xie, and Dennis K. Stone: Identification and Reconstitution of an Isoform of the 116-kDa Subunit of the Vacuolar Proton Translocating ATPase
J. Biol. Chem. 1999 274: 2549-2555. First Published ; doi:10.1074/jbc.274.4.2549 [Abstract] [Full Text] [PDF]

Muthu Periasamy, Thomas D. Reed, Lynne H. Liu, Yong Ji, Evgeny Loukianov, Richard J. Paul, Michelle L. Nieman, Tara Riddle, John J. Duffy, Thomas Doetschman, John N. Lorenz, and Gary E. Shull: Impaired Cardiac Performance in Heterozygous Mice with a Null Mutation in the Sarco(endo)plasmic Reticulum Ca²⁺-ATPase Isoform 2 (SERCA2) Gene
J. Biol. Chem. 1999 274: 2556-2562. First Published ; doi:10.1074/jbc.274.4.2556 [Abstract] [Full Text] [PDF]

Nucleic Acids, Protein Synthesis, and Molecular Genetics:

M. R. Sandhya Rani, Cristina Gauzzi, Sandra Pellegrini, Eleanor N. Fish, Tao Wei, and Richard M. Ransohoff: Induction of $beta$ -R1/I-TAC by Interferon- $beta$ Requires Catalytically Active TYK2
J. Biol. Chem. 1999 274: 1891-1897. First Published ; doi:10.1074/jbc.274.4.1891 [Abstract] [Full Text] [PDF]

Sabrina Venditti, Miguel A. Vega-Palas, and Ernesto Di Mauro: Heterochromatin Organization of a Natural Yeast Telomere. RECRUITMENT OF Sir3p THROUGH INTERACTION WITH HISTONE H4 N TERMINUS IS REQUIRED FOR THE ESTABLISHMENT OF REPRESSIVE STRUCTURES
J. Biol. Chem. 1999 274: 1928-1933. First Published ; doi:10.1074/jbc.274.4.1928 [Abstract] [Full Text] [PDF]

Edwige Nicodeme, Fabienne Benoist, Roger McLeod, Zemin Yao, James Scott, Carol C. Shoulders, and Thierry Grand-Perret: Identification of Domains in Apolipoprotein B100 That Confer a High Requirement for the Microsomal Triglyceride Transfer Protein
J. Biol. Chem. 1999 274: 1986-1993. First Published ; doi:10.1074/jbc.274.4.1986 [Abstract] [Full Text] [PDF]

Dawit T. Haile and Jeffrey D. Parvin: Activation of Transcription in Vitro by the BRCA1 Carboxyl-terminal Domain
J. Biol. Chem. 1999 274: 2113-2117. First Published ; doi:10.1074/jbc.274.4.2113 [Abstract] [Full Text] [PDF]

Ruth Carter Borghaei, Christine Sullivan, and Eugene Mochan: Identification of a Cytokine-induced Repressor of Interleukin-1 Stimulated Expression of Stromelysin 1 (MMP-3)
J. Biol. Chem. 1999 274: 2126-2131. First Published ; doi:10.1074/jbc.274.4.2126 [Abstract] [Full Text] [PDF]

Shuhei Kameya, Yuko Miyagoe, Ikuya Nonaka, Takaaki Ikemoto, Makoto Endo, Kazunori Hanaoka, Yo-ichi Nabeshima, and Shin'ichi Takeda: $alpha$ 1-Syntrophin Gene Disruption Results in the Absence of Neuronal-type Nitric-oxide Synthase at the Sarcolemma but Does Not Induce Muscle Degeneration
J. Biol. Chem. 1999 274: 2193-2200. First Published ; doi:10.1074/jbc.274.4.2193 [Abstract] [Full Text] [PDF]

Alistair McGregor, James B. Murray, Chris J. Adams, Peter G. Stockley, and Bernard A. Connolly: Secondary Structure Mapping of an RNA Ligand That Has High Affinity for the MetJ Repressor Protein and Interference Modification Analysis of the Protein-RNA Complex
J. Biol. Chem. 1999 274: 2255-2262. First Published ; doi:10.1074/jbc.274.4.2255 [Abstract] [Full Text] [PDF]

Jonathan A. Bown, Jeffrey T. Owens, Claude F. Meares, Nobuyuki Fujita, Akira Ishihama, Stephen J. W. Busby, and Stephen D. Minchin: Organization of Open Complexes at Escherichia coli Promoters. LOCATION OF PROMOTER DNA SITES CLOSE TO REGION 2.5 OF THE $sigma$ ⁷⁰ SUBUNIT OF RNA POLYMERASE
J. Biol. Chem. 1999 274: 2263-2270. First Published ; doi:10.1074/jbc.274.4.2263 [Abstract] [Full Text] [PDF]

M. Mar González-Pérez, Juan L. Ramos, María-Trinidad Gallegos, and Silvia Marqués: Critical Nucleotides in the Upstream Region of the XylS-dependent TOL meta-Cleavage Pathway Operon Promoter as Deduced from Analysis of Mutants
J. Biol. Chem. 1999 274: 2286-2290. First Published ; doi:10.1074/jbc.274.4.2286 [Abstract] [Full Text] [PDF]

Julie Lavie, Frédéric Dandré, Huguette Louis, Jean-Marie Daniel Lamazière, and Jacques Bonnet: Vascular Cell Adhesion Molecule-1 Gene Expression during Human Smooth Muscle Cell Differentiation Is Independent of NF- $kappa$ B Activation
J. Biol. Chem. 1999 274: 2308-2314. First Published ; doi:10.1074/jbc.274.4.2308 [Abstract] [Full Text] [PDF]

Cyril Gueydan, Louis Droogmans, Pascale Chalon, Georges Huez, Daniel Caput, and Véronique Kruys: Identification of TIAR as a Protein Binding to the Translational Regulatory AU-rich Element of Tumor Necrosis Factor $alpha$ mRNA
J. Biol. Chem. 1999 274: 2322-2326. First Published ; doi:10.1074/jbc.274.4.2322 [Abstract] [Full Text] [PDF]

Chi Tarn, Matthew L. Bilodeau, Ronald L. Hullinger, and Ourania M. Andrisani: Differential Immediate Early Gene Expression in Conditional Hepatitis B Virus pX-transforming Versus Nontransforming Hepatocyte Cell Lines
J. Biol. Chem. 1999 274: 2327-2336. First Published ; doi:10.1074/jbc.274.4.2327 [Abstract] [Full Text] [PDF]

Lucia Jordá, Alberto Coego, Vicente Conejero, and Pablo Vera: A Genomic Cluster Containing Four Differentially Regulated Subtilisin-like Processing Protease Genes Is in Tomato Plants
J. Biol. Chem. 1999 274: 2360-2365. First Published ; doi:10.1074/jbc.274.4.2360 [Abstract] [Full Text] [PDF]

Uma R. Chandran, Barbour S. Warren, Christopher T. Baumann, Gordon L. Hager, and Donald B. DeFranco: The Glucocorticoid Receptor Is Tethered to DNA-bound Oct-1 at the Mouse Gonadotropin-releasing Hormone Distal Negative Glucocorticoid Response Element
J. Biol. Chem. 1999 274: 2372-2378. First Published ; doi:10.1074/jbc.274.4.2372 [Abstract] [Full Text] [PDF]

Stefan A. Kohler, Eric Menotti, and Lukas C. Kühn: Molecular Cloning of Mouse Glycolate Oxidase. HIGH EVOLUTIONARY CONSERVATION AND PRESENCE OF AN IRON-RESPONSIVE ELEMENT-LIKE SEQUENCE IN THE mRNA
J. Biol. Chem. 1999 274: 2401-2407. First Published ; doi:10.1074/jbc.274.4.2401 [Abstract] [Full Text] [PDF]

Leslie A. Krushel, Bruce A. Cunningham, Gerald M. Edelman, and Kathryn L. Crossin: NF- $kappa$ B Activity Is Induced by Neural Cell Adhesion Molecule Binding to Neurons and Astrocytes
J. Biol. Chem. 1999 274: 2432-2439. First Published ; doi:10.1074/jbc.274.4.2432 [Abstract] [Full Text] [PDF]

André Verdel and Saadi Khochbin: Identification of a New Family of Higher Eukaryotic Histone Deacetylases. COORDINATE EXPRESSION OF DIFFERENTIATION-DEPENDENT CHROMATIN MODIFIERS
J. Biol. Chem. 1999 274: 2440-2445. First Published ; doi:10.1074/jbc.274.4.2440 [Abstract] [Full Text] [PDF]

Dongsheng Chen, Philip S. Rudland, Hai-Lan Chen, and Roger Barraclough: Differential Reactivity of the Rat S100A4(p9Ka) Gene to Sodium Bisulfite Is Associated with Differential Levels of the S100A4 (p9Ka) mRNA in Rat Mammary Epithelial Cells
J. Biol. Chem. 1999 274: 2483-2491. First Published ; doi:10.1074/jbc.274.4.2483 [Abstract] [Full Text] [PDF]

Waltke R. Paulding and Maria F. Czyzyk-Krzeska: Regulation of Tyrosine Hydroxylase mRNA Stability by Protein-binding, Pyrimidine-rich Sequence in the 3'-Untranslated Region
J. Biol. Chem. 1999 274: 2532-2538. First Published ; doi:10.1074/jbc.274.4.2532 [Abstract] [Full Text] [PDF]

Protein Chemistry and Structure:

Sabine Kraft, Beate Diefenbach, Raj Mehta, Alfred Jonczyk, G. Albrecht Luckenbach, and Simon L. Goodman: Definition of an Unexpected Ligand Recognition Motif for $alpha$ v $beta$ 6 Integrin
J. Biol. Chem. 1999 274: 1979-1985. First Published ; doi:10.1074/jbc.274.4.1979 [Abstract] [Full Text] [PDF]

Abdu I. Alayash, Beth A. Brockner Ryan, Raymond F. Eich, John S. Olson, and Robert E. Cashon: Reactions of Sperm Whale Myoglobin with Hydrogen Peroxide. EFFECTS OF DISTAL POCKET MUTATIONS ON THE FORMATION AND STABILITY OF THE FERRYL INTERMEDIATE
J. Biol. Chem. 1999 274: 2029-2037. First Published ; doi:10.1074/jbc.274.4.2029 [Abstract] [Full Text] [PDF]

Lisa Cherry, Nick Menhart, and Leslie Wo-Mei Fung: Interactions of the $alpha$ -Spectrin N-terminal Region with $beta$ -Spectrin. IMPLICATIONS FOR THE SPECTRIN TETRAMERIZATION REACTION
J. Biol. Chem. 1999 274: 2077-2084. First Published ; doi:10.1074/jbc.274.4.2077 [Abstract] [Full Text] [PDF]

Kunihiko Tanaka, Gregorio D. Chazenbalk, Sandra M. McLachlan, and Basil Rapoport: Thyrotropin Receptor Cleavage at Site 1 Involves Two Discontinuous Segments at Each End of the Unique 50-Amino Acid Insertion
J. Biol. Chem. 1999 274: 2093-2096. First Published ; doi:10.1074/jbc.274.4.2093 [Abstract] [Full Text] [PDF]

Julie Blasioli, Silke Paust, and Matthew L. Thomas: Definition of the Sites of Interaction between the Protein Tyrosine Phosphatase SHP-1 and CD22
J. Biol. Chem. 1999 274: 2303-2307. First Published ; doi:10.1074/jbc.274.4.2303 [Abstract] [Full Text] [PDF]

Juha Rouvinen, Jaakko Rautiainen, Tuomas Virtanen, Thomas Zeiler, Juha Kauppinen, Antti Taivainen, and Rauno Mäntyjärvi: Probing the Molecular Basis of Allergy. THREE-DIMENSIONAL STRUCTURE OF THE BOVINE LIPOCALIN ALLERGEN Bos d 2
J. Biol. Chem. 1999 274: 2337-2343. First Published ; doi:10.1074/jbc.274.4.2337 [Abstract] [Full Text] [PDF]

Chii-Shen Yang, Nikolai P. Skiba, Maria R. Mazzoni, and Heidi E. Hamm: Conformational Changes at The Carboxyl Terminus of G $alpha$ Occur during G Protein Activation
J. Biol. Chem. 1999 274: 2379-2385. First Published ; doi:10.1074/jbc.274.4.2379 [Abstract] [Full Text] [PDF]

Joseph Petrosino, Gary Rudgers, Hiram Gilbert, and Timothy Palzkill: Contributions of Aspartate 49 and Phenylalanine 142 Residues of a Tight Binding Inhibitory Protein of $beta$ -Lactamases
J. Biol. Chem. 1999 274: 2394-2400. First Published ; doi:10.1074/jbc.274.4.2394 [Abstract] [Full Text] [PDF]

Jean-Claude Thomas and Chantal Passaquet: Characterization of a Phycoerythrin without $alpha$ -Subunits from a Unicellular Red Alga
J. Biol. Chem. 1999 274: 2472-2482. First Published ; doi:10.1074/jbc.274.4.2472 [Abstract] [Full Text] [PDF]

Silvia Pizzi, Giorgio Dieci, Paolo Frigeri, Giovanni Piccoli, Vilberto Stocchi, and Simone Ottonello: Domain Organization and Functional Properties of Yeast Transcription Factor IIIA Species with Different Zinc Stoichiometries
J. Biol. Chem. 1999 274: 2539-2548. First Published ; doi:10.1074/jbc.274.4.2539 [Abstract] [Full Text] [PDF]

Kenji Yamada, Tomoo Shimada, Maki Kondo, Mikio Nishimura, and Ikuko Hara-Nishimura: Multiple Functional Proteins Are Produced by Cleaving Asn-Gln Bonds of a Single Precursor by Vacuolar Processing Enzyme
J. Biol. Chem. 1999 274: 2563-2570. First Published ; doi:10.1074/jbc.274.4.2563 [Abstract] [Full Text] [PDF]

Michael P. Doyle, Izydor Apostol, and Bruce A. Kerwin: Glutaraldehyde Modification of Recombinant Human Hemoglobin Alters Its Hemodynamic Properties
J. Biol. Chem. 1999 274: 2583-2591. First Published ; doi:10.1074/jbc.274.4.2583 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Hiderou Yoshida, Kyosuke Haze, Hideki Yanagi, Takashi Yura, and Kazutoshi Mori: Additions and Corrections to Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors.
J. Biol. Chem. 1999 274: 2592. [Full Text] [PDF]

Stephan Ruetz, Martine Brault, Christina Kast, Charles Hemenway, Joseph Heitman, Caroline E. Grant, Susan P. C. Cole, Roger G. Deeley, and Philippe Gros: Additions and Corrections to Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
J. Biol. Chem. 1999 274: 2592. [Full Text] [PDF]

Minireviews:

Enzymology:

Communications:

Carbohydrates, Lipids, and Other Natural Products:

Cell Biology and Metabolism:

Membranes and Bioenergetics:

Nucleic Acids, Protein Synthesis, and Molecular Genetics:

Protein Chemistry and Structure:

Additions and Corrections: