Minireviews

Sachiko Tsukita and Shigenobu Yonemura

Cortical Actin Organization: Lessons from ERM (Ezrin/Radixin/Moesin) Proteins
J. Biol. Chem. 1999 274: 34507-34510. [Full Text] [PDF]  

Communications

Paul L. Darke, Amanda R. Jacobs, Lloyd Waxman, and Lawrence C. Kuo

Inhibition of Hepatitis C Virus NS2/3 Processing by NS4A Peptides. IMPLICATIONS FOR CONTROL OF VIRAL PROCESSING
J. Biol. Chem. 1999 274: 34511-34514. [Abstract] [Full Text] [PDF]  

Satoshi Matsuda, Tomoko Suzuki-Fujimoto, Akiko Minowa, Hideki Ueno, Kenji Katamura, and Shigeo Koyasu

Temperature-sensitive ZAP70 Mutants Degrading through a Proteasome-independent Pathway. RESTORATION OF A KINASE DOMAIN MUTANT BY Cdc37
J. Biol. Chem. 1999 274: 34515-34518. [Abstract] [Full Text] [PDF]  

Matthew A. Leff, Adrian J. Fretland, Mark A. Doll, and David W. Hein

Novel Human N-Acetyltransferase 2 Alleles That Differ in Mechanism for Slow Acetylator Phenotype
J. Biol. Chem. 1999 274: 34519-34522. [Abstract] [Full Text] [PDF]  

Takaki Koide, Shinichi Asada, and Kazuhiro Nagata

Substrate Recognition of Collagen-specific Molecular Chaperone HSP47. STRUCTURAL REQUIREMENTS AND BINDING REGULATION
J. Biol. Chem. 1999 274: 34523-34526. [Abstract] [Full Text] [PDF]  

Tsu-Ju Fu, Junmin Peng, Gary Lee, David H. Price, and Osvaldo Flores

Cyclin K Functions as a CDK9 Regulatory Subunit and Participates in RNA Polymerase II Transcription
J. Biol. Chem. 1999 274: 34527-34530. [Abstract] [Full Text] [PDF]  

Julie A. Pitcher, John J. G. Tesmer, Jennifer L. R. Freeman, W. Darrell Capel, W. Carl Stone, and Robert J. Lefkowitz

Feedback Inhibition of G Protein-coupled Receptor Kinase 2 (GRK2) Activity by Extracellular Signal-regulated Kinases
J. Biol. Chem. 1999 274: 34531-34534. [Abstract] [Full Text] [PDF]  

James E. Porter and Dianne M. Perez

Characteristics for a Salt-bridge Switch Mutation of the _1b Adrenergic Receptor. ALTERED PHARMACOLOGY AND RESCUE OF CONSTITUTIVE ACTIVITY
J. Biol. Chem. 1999 274: 34535-34538. [Abstract] [Full Text] [PDF]  

Isabelle Krimm, Aymeric Goyer, Emmanuelle Issakidis-Bourguet, Myroslawa Miginiac-Maslow, and Jean-Marc Lancelin

Direct NMR Observation of the Thioredoxin-mediated Reduction of the Chloroplast NADP-malate Dehydrogenase Provides a Structural Basis for the Relief of Autoinhibition
J. Biol. Chem. 1999 274: 34539-34542. [Abstract] [Full Text] [PDF]  

William C. Barrett, Jon P. DeGnore, Yen-Fang Keng, Zhong-Yin Zhang, Moon B. Yim, and P. Boon Chock

Roles of Superoxide Radical Anion in Signal Transduction Mediated by Reversible Regulation of Protein-tyrosine Phosphatase 1B
J. Biol. Chem. 1999 274: 34543-34546. [Abstract] [Full Text] [PDF]  

Carbohydrates, Lipids, and Other Natural Products

Yeongjin Hong, Yusuke Maeda, Reika Watanabe, Kazuhito Ohishi, Michael Mishkind, Howard Riezman, and Taroh Kinoshita

Pig-n, a Mammalian Homologue of Yeast Mcd4p, Is Involved in Transferring Phosphoethanolamine to the First Mannose of the Glycosylphosphatidylinositol
J. Biol. Chem. 1999 274: 35099-35106. [Abstract] [Full Text] [PDF]  

Mario F. Feldman, Cristina L. Marolda, Mario A. Monteiro, Malcolm B. Perry, Armando J. Parodi, and Miguel A. Valvano

The Activity of a Putative Polyisoprenol-linked Sugar Translocase (Wzx) Involved in Escherichia coli O Antigen Assembly Is Independent of the Chemical Structure of the O Repeat
J. Biol. Chem. 1999 274: 35129-35138. [Abstract] [Full Text] [PDF]  

Gwo-Jenn Shen, Arun K. Datta, Masayuki Izumi, Kathryn M. Koeller, and Chi-Huey Wong

Expression of 2,8/2,9-Polysialyltransferase from Escherichia coli K92. CHARACTERIZATION OF THE ENZYME AND ITS REACTION PRODUCTS
J. Biol. Chem. 1999 274: 35139-35146. [Abstract] [Full Text] [PDF]  

Yohko U. Katagiri, Tetsuya Mori, Hideki Nakajima, Chihiro Katagiri, Tomoko Taguchi, Tae Takeda, Nobutaka Kiyokawa, and Junichiro Fujimoto

Activation of Src Family Kinase Yes Induced by Shiga Toxin Binding to Globotriaosyl Ceramide (Gb3/CD77) in Low Density, Detergent-insoluble Microdomains
J. Biol. Chem. 1999 274: 35278-35282. [Abstract] [Full Text] [PDF]  

Cell Biology and Metabolism

Hankyoung Pyo, Eun-hye Joe, Soyoung Jung, Soo Hwan Lee, and Ilo Jou

Gangliosides Activate Cultured Rat Brain Microglia
J. Biol. Chem. 1999 274: 34584-34589. [Abstract] [Full Text] [PDF]  

Katherine L. Olin, Susan Potter-Perigo, P. Hugh R. Barrett, Thomas N. Wight, and Alan Chait

Lipoprotein Lipase Enhances the Binding of Native and Oxidized Low Density Lipoproteins to Versican and Biglycan Synthesized by Cultured Arterial Smooth Muscle Cells
J. Biol. Chem. 1999 274: 34629-34636. [Abstract] [Full Text] [PDF]  

Annemarie Weber, Cynthia R. Pennise, and Velia M. Fowler

Tropomodulin Increases the Critical Concentration of Barbed End-capped Actin Filaments by Converting ADP·P_i-actin to ADP-actin at All Pointed Filament Ends
J. Biol. Chem. 1999 274: 34637-34645. [Abstract] [Full Text] [PDF]  

Benjamin D. Caldwell, Daniel N. Darlington, Peter Penzes, Richard C. Johnson, Betty A. Eipper, and Richard E. Mains

The Novel Kinase Peptidylglycine -Amidating Monooxygenase Cytosolic Interactor Protein 2 Interacts with the Cytosolic Routing Determinants of the Peptide Processing Enzyme Peptidylglycine -Amidating Monooxygenase
J. Biol. Chem. 1999 274: 34646-34656. [Abstract] [Full Text] [PDF]  

Yong-kang Zhang, Xiangao Sun, Kei-ichi Muraoka, Akiko Ikeda, Shigeki Miyamoto, Hiroko Shimizu, Katsuji Yoshioka, and Ken-ichi Yamamoto

Immunosuppressant FK506 Activates NF-B through the Proteasome-mediated Degradation of IB. REQUIREMENT FOR IB N-TERMINAL PHOSPHORYLATION BUT NOT UBIQUITINATION SITES
J. Biol. Chem. 1999 274: 34657-34662. [Abstract] [Full Text] [PDF]  

Kiyotsugu Yoshida, Surender Kharbanda, and Donald Kufe

Functional Interaction between SHPTP1 and the Lyn Tyrosine Kinase in the Apoptotic Response to DNA Damage
J. Biol. Chem. 1999 274: 34663-34668. [Abstract] [Full Text] [PDF]  

Katarzyna Cieslik, Chii-Ming Lee, Jih-Luh Tang, and Kenneth K. Wu

Transcriptional Regulation of Endothelial Nitric-oxide Synthase by an Interaction between Casein Kinase 2 and Protein Phosphatase 2A
J. Biol. Chem. 1999 274: 34669-34675. [Abstract] [Full Text] [PDF]  

Ger J. J. C. Boonen, Brigitte A. van Oirschot, Angela van Diepen, Wendy J. M. Mackus, Leo F. Verdonck, Gert Rijksen, and René H. Medema

Cyclin D3 Regulates Proliferation and Apoptosis of Leukemic T Cell Lines
J. Biol. Chem. 1999 274: 34676-34682. [Abstract] [Full Text] [PDF]  

Matthias Voß, Paschal A. Oude Weernink, Stephan Haupenthal, Ursula Möller, Robbert H. Cool, Bettina Bauer, Jacques H. Camonis, Karl H. Jakobs, and Martina Schmidt

Phospholipase D Stimulation by Receptor Tyrosine Kinases Mediated by Protein Kinase C and a Ras/Ral Signaling Cascade
J. Biol. Chem. 1999 274: 34691-34698. [Abstract] [Full Text] [PDF]  

Davey Parekh, Wolfgang Ziegler, Kazu Yonezawa, Kenta Hara, and Peter J. Parker

Mammalian TOR Controls One of Two Kinase Pathways Acting upon nPKC and nPKC
J. Biol. Chem. 1999 274: 34758-34764. [Abstract] [Full Text] [PDF]  

Michelangelo Foti, Laetitia Cartier, Vincent Piguet, Daniel P. Lew, Jean-Louis Carpentier, Didier Trono, and Karl-Heinz Krause

The HIV Nef Protein Alters Ca²⁺ Signaling in Myelomonocytic Cells through SH3-mediated Protein-Protein Interactions
J. Biol. Chem. 1999 274: 34765-34772. [Abstract] [Full Text] [PDF]  

Gary D. Kao, W. Gillies McKenna, and Ruth J. Muschel

p34^Cdc2 Kinase Activity Is Excluded from the Nucleus during the Radiation-induced G₂ Arrest in HeLa Cells
J. Biol. Chem. 1999 274: 34779-34784. [Abstract] [Full Text] [PDF]  

Arasu Chellaiah, Wenlin Yuan, Meenakshi Chellaiah, and David M. Ornitz

Mapping Ligand Binding Domains in Chimeric Fibroblast Growth Factor Receptor Molecules. MULTIPLE REGIONS DETERMINE LIGAND BINDING SPECIFICITY
J. Biol. Chem. 1999 274: 34785-34794. [Abstract] [Full Text] [PDF]  

Johannes Klein, Mathias Fasshauer, Moriko Ito, Bradford B. Lowell, Manuel Benito, and C. Ronald Kahn

₃-Adrenergic Stimulation Differentially Inhibits Insulin Signaling and Decreases Insulin-induced Glucose Uptake in Brown Adipocytes
J. Biol. Chem. 1999 274: 34795-34802. [Abstract] [Full Text] [PDF]  

Yuji Nishikawa, Ziqiu Wang, Jeffrey Kerns, Craig S. Wilcox, and Brian I. Carr

Inhibition of Hepatoma Cell Growth in Vitro by Arylating and Non-arylating K Vitamin Analogs. SIGNIFICANCE OF PROTEIN TYROSINE PHOSPHATASE INHIBITION
J. Biol. Chem. 1999 274: 34803-34810. [Abstract] [Full Text] [PDF]  

Joseph M. Bosilevac, Randall J. Olsen, Julia A. Bridge, and Steven H. Hinrichs

Tumor Cell Viability in Clear Cell Sarcoma Requires DNA Binding Activity of the EWS/ATF1 Fusion Protein
J. Biol. Chem. 1999 274: 34811-34818. [Abstract] [Full Text] [PDF]  

Els Pattyn, Xaveer Van Ostade, Liesbeth Schauvliege, Annick Verhee, Michael Kalai, Joël Vandekerckhove, and Jan Tavernier

Dimerization of the Interferon Type I Receptor IFNaR2-2 Is Sufficient for Induction of Interferon Effector Genes but Not for Full Antiviral Activity
J. Biol. Chem. 1999 274: 34838-34845. [Abstract] [Full Text] [PDF]  

Sabina Capellari, Syed I. A. Zaidi, Cynthia B. Urig, George Perry, Mark A. Smith, and Robert B. Petersen

Prion Protein Glycosylation Is Sensitive to Redox Change
J. Biol. Chem. 1999 274: 34846-34850. [Abstract] [Full Text] [PDF]  

Yi Tan, Hong Ruan, Matthew R. Demeter, and Michael J. Comb

p90^RSK Blocks Bad-mediated Cell Death via a Protein Kinase C-dependent Pathway
J. Biol. Chem. 1999 274: 34859-34867. [Abstract] [Full Text] [PDF]  

Steven A. Stacker, Angela Vitali, Carol Caesar, Teresa Domagala, Leo C. Groenen, Edouard Nice, Marc G. Achen, and Andrew F. Wilks

A Mutant Form of Vascular Endothelial Growth Factor (VEGF) That Lacks VEGF Receptor-2 Activation Retains the Ability to Induce Vascular Permeability
J. Biol. Chem. 1999 274: 34884-34892. [Abstract] [Full Text] [PDF]  

Weiqin Zhao, Hui Chen, Hui Xu, Elizabeth Moore, Noam Meiri, Michael J. Quon, and Daniel L. Alkon

Brain Insulin Receptors and Spatial Memory. CORRELATED CHANGES IN GENE EXPRESSION, TYROSINE PHOSPHORYLATION, AND SIGNALING MOLECULES IN THE HIPPOCAMPUS OF WATER MAZE TRAINED RATS
J. Biol. Chem. 1999 274: 34893-34902. [Abstract] [Full Text] [PDF]  

Arianna L. Kim, Anthony J. Raffo, Paul W. Brandt-Rauf, Matthew R. Pincus, Regina Monaco, Patricio Abarzua, and Robert L. Fine

Conformational and Molecular Basis for Induction of Apoptosis by a p53 C-terminal Peptide in Human Cancer Cells
J. Biol. Chem. 1999 274: 34924-34931. [Abstract] [Full Text] [PDF]  

Hiroyasu Inada, Hideaki Togashi, Yu Nakamura, Kozo Kaibuchi, Koh-ichi Nagata, and Masaki Inagaki

Balance between Activities of Rho Kinase and Type 1 Protein Phosphatase Modulates Turnover of Phosphorylation and Dynamics of Desmin/Vimentin Filaments
J. Biol. Chem. 1999 274: 34932-34939. [Abstract] [Full Text] [PDF]  

Lidia C. Sambucetti, Denise D. Fischer, Sonya Zabludoff, Paul O. Kwon, Helena Chamberlin, Nancy Trogani, Hong Xu, and Dalia Cohen

Histone Deacetylase Inhibition Selectively Alters the Activity and Expression of Cell Cycle Proteins Leading to Specific Chromatin Acetylation and Antiproliferative Effects
J. Biol. Chem. 1999 274: 34940-34947. [Abstract] [Full Text] [PDF]  

Marilyne Levadoux, Connor Mahon, John H. Beattie, Heather M. Wallace, and John E. Hesketh

Nuclear Import of Metallothionein Requires Its mRNA to Be Associated with the Perinuclear Cytoskeleton
J. Biol. Chem. 1999 274: 34961-34966. [Abstract] [Full Text] [PDF]  

Alfred A. Reszka, Judit M. Halasy-Nagy, Patricia J. Masarachia, and Gideon A. Rodan

Bisphosphonates Act Directly on the Osteoclast to Induce Caspase Cleavage of Mst1 Kinase during Apoptosis. A LINK BETWEEN INHIBITION OF THE MEVALONATE PATHWAY AND REGULATION OF AN APOPTOSIS-PROMOTING KINASE
J. Biol. Chem. 1999 274: 34967-34973. [Abstract] [Full Text] [PDF]  

Frank Ender, Armin Hallmann, Peter Amon, and Manfred Sumper

Response to the Sexual Pheromone and Wounding in the Green Alga Volvox: Induction of an Extracellular Glycoprotein Consisting Almost Exclusively of Hydroxyproline
J. Biol. Chem. 1999 274: 35023-35028. [Abstract] [Full Text] [PDF]  

Michel Ouellet, Benoit Barbeau, and Michel J. Tremblay

p56^lck, ZAP-70, SLP-76, and Calcium-regulated Effectors Are Involved in NF-B Activation by Bisperoxovanadium Phosphotyrosyl Phosphatase Inhibitors in Human T Cells
J. Biol. Chem. 1999 274: 35029-35036. [Abstract] [Full Text] [PDF]  

Qi-Quan Huang, Steven A. Fisher, and Frank V. Brozovich

Forced Expression of Essential Myosin Light Chain Isoforms Demonstrates Their Role in Smooth Muscle Force Production
J. Biol. Chem. 1999 274: 35095-35098. [Abstract] [Full Text] [PDF]  

Alessandra Pacini, Alessandro Quattrone, Marco Denegri, Claudia Fiorillo, Chiara Nediani, Santiago Ramon y Cajal, and Paolo Nassi

Transcriptional Down-regulation of Poly(ADP-ribose) Polymerase Gene Expression by E1A Binding to pRb Proteins Protects Murine Keratinocytes from Radiation-induced Apoptosis
J. Biol. Chem. 1999 274: 35107-35112. [Abstract] [Full Text] [PDF]  

Debra Meyer, Albert Liu, and Ben Margolis

Interaction of c-Jun Amino-terminal Kinase Interacting Protein-1 with p190 rhoGEF and Its Localization in Differentiated Neurons
J. Biol. Chem. 1999 274: 35113-35118. [Abstract] [Full Text] [PDF]  

Hideto Yonekura, Shigeru Sakurai, Xiaoxu Liu, Hideyuki Migita, Hua Wang, Sho-ichi Yamagishi, Motohiro Nomura, Md. Joynal Abedin, Hiroyuki Unoki, Yasuhiko Yamamoto, and Hiroshi Yamamoto

Placenta Growth Factor and Vascular Endothelial Growth Factor B and C Expression in Microvascular Endothelial Cells and Pericytes. IMPLICATION IN AUTOCRINE AND PARACRINE REGULATION OF ANGIOGENESIS
J. Biol. Chem. 1999 274: 35172-35178. [Abstract] [Full Text] [PDF]  

Erika S. Wittchen, Julie Haskins, and Bruce R. Stevenson

Protein Interactions at the Tight Junction. ACTIN HAS MULTIPLE BINDING PARTNERS, AND ZO-1 FORMS INDEPENDENT COMPLEXES WITH ZO-2 AND ZO-3
J. Biol. Chem. 1999 274: 35179-35185. [Abstract] [Full Text] [PDF]  

Henry P. Ciolino and Grace Chao Yeh

The Steroid Hormone Dehydroepiandrosterone Inhibits CYP1A1 Expression in Vitro By a Post-transcriptional Mechanism
J. Biol. Chem. 1999 274: 35186-35190. [Abstract] [Full Text] [PDF]  

Eduard B. Babiychuk, Robert-Jan T. S. Palstra, Johann Schaller, Urs Kämpfer, and Annette Draeger

Annexin VI Participates in the Formation of a Reversible, Membrane-Cytoskeleton Complex in Smooth Muscle Cells
J. Biol. Chem. 1999 274: 35191-35195. [Abstract] [Full Text] [PDF]  

Luisa Martínez-Pomares, Paul R. Crocker, Rosangela Da Silva, Nick Holmes, Cristina Colominas, Pauline Rudd, Raymond Dwek, and Siamon Gordon

Cell-specific Glycoforms of Sialoadhesin and CD45 Are Counter-receptors for the Cysteine-rich Domain of the Mannose Receptor
J. Biol. Chem. 1999 274: 35211-35218. [Abstract] [Full Text] [PDF]  

Bart J. M. van Vlijmen, Astrid Rohlmann, Shallee T. Page, André Bensadoun, I. Sophie T. Bos, Theo J. C. van Berkel, Louis M. Havekes, and Joachim Herz

An Extrahepatic Receptor-associated Protein-sensitive Mechanism Is Involved in the Metabolism of Triglyceride-rich Lipoproteins
J. Biol. Chem. 1999 274: 35219-35226. [Abstract] [Full Text] [PDF]  

Helmut Jacobsen, Dieter Reinhardt, Manfred Brockhaus, Daniel Bur, Christine Kocyba, Hanspeter Kurt, Melissa G. Grim, Ralf Baumeister, and Hansruedi Loetscher

The Influence of Endoproteolytic Processing of Familial Alzheimer's Disease Presenilin 2 on A42 Amyloid Peptide Formation
J. Biol. Chem. 1999 274: 35233-35239. [Abstract] [Full Text] [PDF]  

Yi Zhang, Soek Ying Neo, Xinghao Wang, Jiahuai Han, and Sheng-Cai Lin

Axin Forms a Complex with MEKK1 and Activates c-Jun NH₂-terminal Kinase/Stress-activated Protein Kinase through Domains Distinct from Wnt Signaling
J. Biol. Chem. 1999 274: 35247-35254. [Abstract] [Full Text] [PDF]  

Chi-Wu Chiang, Nicola Carter, William J. Sullivan Jr., Robert G. K. Donald, David S. Roos, Fardos N. M. Naguib, Mahmoud H. el Kouni, Buddy Ullman, and Craig M. Wilson

The Adenosine Transporter of Toxoplasma gondii. IDENTIFICATION BY INSERTIONAL MUTAGENESIS, CLONING, AND RECOMBINANT EXPRESSION
J. Biol. Chem. 1999 274: 35255-35261. [Abstract] [Full Text] [PDF]  

Shingo Akiyoshi, Hirofumi Inoue, Jun-ichi Hanai, Kiyoshi Kusanagi, Nobuo Nemoto, Kohei Miyazono, and Masahiro Kawabata

c-Ski Acts as a Transcriptional Co-repressor in Transforming Growth Factor- Signaling through Interaction with Smads
J. Biol. Chem. 1999 274: 35269-35277. [Abstract] [Full Text] [PDF]  

Enzymology

Sharon J. Schultz, Miaohua Zhang, Colleen D. Kelleher, and James J. Champoux

Polypurine Tract Primer Generation and Utilization by Moloney Murine Leukemia Virus Reverse Transcriptase
J. Biol. Chem. 1999 274: 34547-34555. [Abstract] [Full Text] [PDF]  

Sornampillai Sankarapandi and Jay L. Zweier

Evidence against the Generation of Free Hydroxyl Radicals from the Interaction of Copper,Zinc-Superoxide Dismutase and Hydrogen Peroxide
J. Biol. Chem. 1999 274: 34576-34583. [Abstract] [Full Text] [PDF]  

Filippa Kull, Eva Ohlson, and Jesper Z. Haeggström

Cloning and Characterization of a Bifunctional Leukotriene A₄ Hydrolase from Saccharomyces cerevisiae
J. Biol. Chem. 1999 274: 34683-34690. [Abstract] [Full Text] [PDF]  

Jill M. Maidment, Darren Moore, George P. Murphy, Gillian Murphy, and Ian M. Clark

Matrix Metalloproteinase Homologues from Arabidopsis thaliana. EXPRESSION AND ACTIVITY
J. Biol. Chem. 1999 274: 34706-34710. [Abstract] [Full Text] [PDF]  

Lori K. Dircks, Jinshan Ke, and Hei Sook Sul

A Conserved Seven Amino Acid Stretch Important for Murine Mitochondrial Glycerol-3-phosphate Acyltransferase Activity. SIGNIFICANCE OF ARGININE 318 IN CATALYSIS
J. Biol. Chem. 1999 274: 34728-34734. [Abstract] [Full Text] [PDF]  

Ilana Shoshani, Valérie Boudou, Claire Pierra, Gilles Gosselin, and Roger A. Johnson

Enzymatic Synthesis of Unlabeled and -³²P-labeled -L-2',3'-Dideoxyadenosine-5'-triphosphate as a Potent Inhibitor of Adenylyl Cyclases and Its Use as Reversible Binding Ligand
J. Biol. Chem. 1999 274: 34735-34741. [Abstract] [Full Text] [PDF]  

Ilana Shoshani, Wolfgang H. G. Laux, Christian Périgaud, Gilles Gosselin, and Roger A. Johnson

Inhibition of Adenylyl Cyclase by Acyclic Nucleoside Phosphonate Antiviral Agents
J. Biol. Chem. 1999 274: 34742-34744. [Abstract] [Full Text] [PDF]  

Sergey Doronin, Leyton Murray, Carmen W. Dessauer, and Roger A. Johnson

Covalent Labeling of Adenylyl Cyclase Cytosolic Domains with -Methylimidazole-2',5'-dideoxy-[-³²P]3'-ATP and the Mechanism for P-site-mediated Inhibition
J. Biol. Chem. 1999 274: 34745-34750. [Abstract] [Full Text] [PDF]  

Jen-Wei Chen, Ying-Ling Luo, Ming-Jing Hwang, Fu-Chuo Peng, and Kuo-Huang Ling

Territrem B, a Tremorgenic Mycotoxin That Inhibits Acetylcholinesterase with a Noncovalent yet Irreversible Binding Mechanism
J. Biol. Chem. 1999 274: 34916-34923. [Abstract] [Full Text] [PDF]  

Shi-Shan Mao, Carolyn M. Cooper, Theresa Wood, Jules A. Shafer, and Stephen J. Gardell

Characterization of Plasmin-mediated Activation of Plasma Procarboxypeptidase B. MODULATION BY GLYCOSAMINOGLYCANS
J. Biol. Chem. 1999 274: 35046-35052. [Abstract] [Full Text] [PDF]  

Membranes and Bioenergetics

Qiang Lü and Kathleen Dunlap

Cloning and Functional Expression of Novel N-type Ca²⁺ Channel Variants
J. Biol. Chem. 1999 274: 34566-34575. [Abstract] [Full Text] [PDF]  

Nicole Lerner-Marmarosh, Khursheed Gimi, Ina L. Urbatsch, Philippe Gros, and Alan E. Senior

Large Scale Purification of Detergent-soluble P-glycoprotein from Pichia pastoris Cells and Characterization of Nucleotide Binding Properties of Wild-type, Walker A, and Walker B Mutant Proteins
J. Biol. Chem. 1999 274: 34711-34718. [Abstract] [Full Text] [PDF]  

B. K. Tamarappoo, Baoxue Yang, and A. S. Verkman

Misfolding of Mutant Aquaporin-2 Water Channels in Nephrogenic Diabetes Insipidus
J. Biol. Chem. 1999 274: 34825-34831. [Abstract] [Full Text] [PDF]  

Isamu Yabe, Ken-ichi Horiuchi, Katsumi Nakahara, Tetsuo Hiyama, Tadae Yamanaka, Pi-Chao Wang, Kiyoshi Toda, Aiko Hirata, Yoshinori Ohsumi, Ryogo Hirata, Yasuhiro Anraku, and Iwao Kusaka

Patch Clamp Studies on V-type ATPase of Vacuolar Membrane of Haploid Saccharomyces cerevisiae. PREPARATION AND UTILIZATION OF A GIANT CELL CONTAINING A GIANT VACUOLE
J. Biol. Chem. 1999 274: 34903-34910. [Abstract] [Full Text] [PDF]  

Grégoire Rossier, Christian Meier, Christian Bauch, Vanessa Summa, Bernard Sordat, François Verrey, and Lukas C. Kühn

LAT2, a New Basolateral 4F2hc/CD98-associated Amino Acid Transporter of Kidney and Intestine
J. Biol. Chem. 1999 274: 34948-34954. [Abstract] [Full Text] [PDF]  

Christine N. Woldin, Frederick S. Hing, Jongsoon Lee, Paul F. Pilch, and G. Graham Shipley

Structural Studies of the Detergent-solubilized and Vesicle-reconstituted Insulin Receptor
J. Biol. Chem. 1999 274: 34981-34992. [Abstract] [Full Text] [PDF]  

Xing-Zhen Chen, Ji-Bin Peng, Adiel Cohen, Hannah Nelson, Nathan Nelson, and Matthias A. Hediger

Yeast SMF1 Mediates H⁺-coupled Iron Uptake with Concomitant Uncoupled Cation Currents
J. Biol. Chem. 1999 274: 35089-35094. [Abstract] [Full Text] [PDF]  

Ariel J. Caride, Nancy L. Elwess, Anil K. Verma, Adelaida G. Filoteo, Ágnes Enyedi, Zeljko Bajzer, and John T. Penniston

The Rate of Activation by Calmodulin of Isoform 4 of the Plasma Membrane Ca²⁺ Pump Is Slow and Is Changed by Alternative Splicing
J. Biol. Chem. 1999 274: 35227-35232. [Abstract] [Full Text] [PDF]  

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Martin Hersberger, Susannah Patarroyo-White, Kay S. Arnold, and Thomas L. Innerarity

Phylogenetic Analysis of the Apolipoprotein B mRNA-editing Region. EVIDENCE FOR A SECONDARY STRUCTURE BETWEEN THE MOORING SEQUENCE AND THE 3' EFFICIENCY ELEMENT
J. Biol. Chem. 1999 274: 34590-34597. [Abstract] [Full Text] [PDF]  

Minoru Satoh, Victoria M. Shaheen, Peter N. Kao, Tetsuroh Okano, Melody Shaw, Hideo Yoshida, Hanno B. Richards, and Westley H. Reeves

Autoantibodies Define a Family of Proteins with Conserved Double-stranded RNA-binding Domains as Well as DNA Binding Activity
J. Biol. Chem. 1999 274: 34598-34604. [Abstract] [Full Text] [PDF]  

Kazuyuki Yanai, Keiko Hirota, Keiko Taniguchi-Yanai, Yoko Shigematsu, Yoko Shimamoto, Tomoko Saito, Shoaib Chowdhury, Masaki Takiguchi, Mayumi Arakawa, Yutaka Nibu, Fumihiro Sugiyama, Ken-ichi Yagami, and Akiyoshi Fukamizu

Regulated Expression of Human Angiotensinogen Gene by Hepatocyte Nuclear Factor 4 and Chicken Ovalbumin Upstream Promoter-Transcription Factor
J. Biol. Chem. 1999 274: 34605-34612. [Abstract] [Full Text] [PDF]  

Ming Yan and Jay D. Gralla

The Use of ATP and Initiating Nucleotides during Postrecruitment Steps at the Activated Adenovirus E4 Promoter
J. Biol. Chem. 1999 274: 34819-34824. [Abstract] [Full Text] [PDF]  

Tatsuo Nunoshiba, Fumiko Obata, Antoine C. Boss, Shinji Oikawa, Toshiaki Mori, Shousuke Kawanishi, and Kazuo Yamamoto

Role of Iron and Superoxide for Generation of Hydroxyl Radical, Oxidative DNA Lesions, and Mutagenesis in Escherichia coli
J. Biol. Chem. 1999 274: 34832-34837. [Abstract] [Full Text] [PDF]  

Eric Billy, Daniel Hess, Jan Hofsteenge, and Witold Filipowicz

Characterization of the Adenylation Site in the RNA 3'-Terminal Phosphate Cyclase from Escherichia coli
J. Biol. Chem. 1999 274: 34955-34960. [Abstract] [Full Text] [PDF]  

Jianping Ye, Suwei Wang, Stephen S. Leonard, Yi Sun, Leon Butterworth, Jim Antonini, Min Ding, Yongyut Rojanasakul, Val Vallyathan, Vincent Castranova, and Xianglin Shi

Role of Reactive Oxygen Species and p53 in Chromium(VI)-induced Apoptosis
J. Biol. Chem. 1999 274: 34974-34980. [Abstract] [Full Text] [PDF]  

Jimo Borjigin, Jie Deng, Michael M. Wang, Xiaodong Li, Seth Blackshaw, and Solomon H. Snyder

Circadian Rhythm of Patched1 Transcription in the Pineal Regulated by Adrenergic Stimulation and cAMP
J. Biol. Chem. 1999 274: 35012-35015. [Abstract] [Full Text] [PDF]  

Jianmin Liu, Martine Antaya, Derek Boerboom, Jacques G. Lussier, David W. Silversides, and Jean Sirois

The Delayed Activation of the Prostaglandin G/H Synthase-2 Promoter in Bovine Granulosa Cells Is Associated with Down-regulation of Truncated Upstream Stimulatory Factor-2
J. Biol. Chem. 1999 274: 35037-35045. [Abstract] [Full Text] [PDF]  

Jeremy N. Rich, Ming Zhang, Michael B. Datto, Darell D. Bigner, and Xiao-Fan Wang

Transforming Growth Factor--mediated p15^INK4B Induction and Growth Inhibition in Astrocytes Is SMAD3-dependent and a Pathway Prominently Altered in Human Glioma Cell Lines
J. Biol. Chem. 1999 274: 35053-35058. [Abstract] [Full Text] [PDF]  

Yu Li and Benjamin J. Blencowe

Distinct Factor Requirements for Exonic Splicing Enhancer Function and Binding of U2AF to the Polypyrimidine Tract
J. Biol. Chem. 1999 274: 35074-35079. [Abstract] [Full Text] [PDF]  

Yuko Hayashi, Masahiro Yamagishi, Yoshio Nishimoto, Osamu Taguchi, Akio Matsukage, and Masamitsu Yamaguchi

A Binding Site for the Transcription Factor Grainyhead/Nuclear Transcription Factor-1 Contributes to Regulation of the Drosophila Proliferating Cell Nuclear Antigen Gene Promoter
J. Biol. Chem. 1999 274: 35080-35088. [Abstract] [Full Text] [PDF]  

Rika Hi, Shiho Osada, Noboru Yumoto, and Takashi Osumi

Characterization of the Amino-terminal Activation Domain of Peroxisome Proliferator-activated Receptor . IMPORTANCE OF -HELICAL STRUCTURE IN THE TRANSACTIVATING FUNCTION
J. Biol. Chem. 1999 274: 35152-35158. [Abstract] [Full Text] [PDF]  

Grethe S. Foss and Hans Prydz

Interferon Regulatory Factor 1 Mediates the Interferon- Induction of the Human Immunoproteasome Subunit Multicatalytic Endopeptidase Complex-like 1
J. Biol. Chem. 1999 274: 35196-35202. [Abstract] [Full Text] [PDF]  

Xiao Rui Li, Anita S.-F. Chong, Jianming Wu, Kenneth A. Roebuck, Aseem Kumar, Joseph E. Parrillo, Ulf R. Rapp, Robert P. Kimberly, James W. Williams, and Xiulong Xu

Transcriptional Regulation of Fas Gene Expression by GA-binding Protein and AP-1 in T Cell Antigen Receptor·CD3 Complex-stimulated T Cells
J. Biol. Chem. 1999 274: 35203-35210. [Abstract] [Full Text] [PDF]  

Xin-Hai Pei, Yoichi Nakanishi, Koichi Takayama, Feng Bai, and Nobuyuki Hara

Benzo[a]pyrene Activates the Human p53 Gene through Induction of Nuclear Factor B Activity
J. Biol. Chem. 1999 274: 35240-35246. [Abstract] [Full Text] [PDF]  

Protein Chemistry and Structure

Susannah J. Bauman and Frank C. Church

Enhancement of Heparin Cofactor II Anticoagulant Activity
J. Biol. Chem. 1999 274: 34556-34565. [Abstract] [Full Text] [PDF]  

Tamara L. Fink, Sharron H. Francis, Alfreda Beasley, Kennard A. Grimes, and Jackie D. Corbin

Expression of an Active, Monomeric Catalytic Domain of the cGMP-binding cGMP-specific Phosphodiesterase (PDE5)
J. Biol. Chem. 1999 274: 34613-34620. [Abstract] [Full Text] [PDF]  

Subramaniam Pennathur, Vernice Jackson-Lewis, Serge Przedborski, and Jay W. Heinecke

Mass Spectrometric Quantification of 3-Nitrotyrosine, ortho-Tyrosine, and o,o'-Dityrosine in Brain Tissue of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated Mice, a Model of Oxidative Stress in Parkinson's Disease
J. Biol. Chem. 1999 274: 34621-34628. [Abstract] [Full Text] [PDF]  

Stéphane Bourque, Marie-Noëlle Binet, Michel Ponchet, Alain Pugin, and Angela Lebrun-Garcia

Characterization of the Cryptogein Binding Sites on Plant Plasma Membranes
J. Biol. Chem. 1999 274: 34699-34705. [Abstract] [Full Text] [PDF]  

Cédric Blanpain, Benjamin J. Doranz, Jalal Vakili, Joseph Rucker, Cédric Govaerts, Sarah S. W. Baik, Olivier Lorthioir, Isabelle Migeotte, Frederick Libert, Françoise Baleux, Gilbert Vassart, Robert W. Doms, and Marc Parmentier

Multiple Charged and Aromatic Residues in CCR5 Amino-terminal Domain Are Involved in High Affinity Binding of Both Chemokines and HIV-1 Env Protein
J. Biol. Chem. 1999 274: 34719-34727. [Abstract] [Full Text] [PDF]  

Mei M. Whittaker and James W. Whittaker

Thermally Triggered Metal Binding by Recombinant Thermus thermophilus Manganese Superoxide Dismutase, Expressed as the Apo-enzyme
J. Biol. Chem. 1999 274: 34751-34757. [Abstract] [Full Text] [PDF]  

Siddhartha A. Datta and Ch. Mohan Rao

Differential Temperature-dependent Chaperone-like Activity of A- and B-crystallin Homoaggregates
J. Biol. Chem. 1999 274: 34773-34778. [Abstract] [Full Text] [PDF]  

Stéphanie Antil, Denis Servent, and André Ménez

Variability among the Sites by Which Curaremimetic Toxins Bind to Torpedo Acetylcholine Receptor, as Revealed by Identification of the Functional Residues of -Cobratoxin
J. Biol. Chem. 1999 274: 34851-34858. [Abstract] [Full Text] [PDF]  

Joost C. M. Uitdehaag, Kor H. Kalk, Bart A. van der Veen, Lubbert Dijkhuizen, and Bauke W. Dijkstra

The Cyclization Mechanism of Cyclodextrin Glycosyltransferase (CGTase) as Revealed by a -Cyclodextrin-CGTase Complex at 1.8-Å Resolution
J. Biol. Chem. 1999 274: 34868-34876. [Abstract] [Full Text] [PDF]  

Jacqueline Dornan, Antony P. Page, Paul Taylor, Su-ying Wu, Alan D. Winter, Holger Husi, and Malcolm D. Walkinshaw

Biochemical and Structural Characterization of a Divergent Loop Cyclophilin from Caenorhabditis elegans
J. Biol. Chem. 1999 274: 34877-34883. [Abstract] [Full Text] [PDF]  

Nadya I. Tarasova, William G. Rice, and Christopher J. Michejda

Inhibition of G-protein-coupled Receptor Function by Disruption of Transmembrane Domain Interactions
J. Biol. Chem. 1999 274: 34911-34915. [Abstract] [Full Text] [PDF]  

Alessandra Devoto, Pietro Piffanelli, IngMarie Nilsson, Erik Wallin, Ralph Panstruga, Gunnar von Heijne, and Paul Schulze-Lefert

Topology, Subcellular Localization, and Sequence Diversity of the Mlo Family in Plants
J. Biol. Chem. 1999 274: 34993-35004. [Abstract] [Full Text] [PDF]  

Anette Henriksen, Andrew T. Smith, and Michael Gajhede

The Structures of the Horseradish Peroxidase C-Ferulic Acid Complex and the Ternary Complex with Cyanide Suggest How Peroxidases Oxidize Small Phenolic Substrates
J. Biol. Chem. 1999 274: 35005-35011. [Abstract] [Full Text] [PDF]  

Ifat Sher, Alexander Weizman, Sharon Lubinsky-Mink, Tamar Lang, Noam Adir, Dietmar Schomburg, and Dina Ron

Mutations Uncouple Human Fibroblast Growth Factor (FGF)-7 Biological Activity and Receptor Binding and Support Broad Specificity in the Secondary Receptor Binding Site of FGFs
J. Biol. Chem. 1999 274: 35016-35022. [Abstract] [Full Text] [PDF]  

Haishan Xiong and Anthony E. Pegg

Mechanistic Studies of the Processing of Human S-Adenosylmethionine Decarboxylase Proenzyme. ISOLATION OF AN ESTER INTERMEDIATE
J. Biol. Chem. 1999 274: 35059-35066. [Abstract] [Full Text] [PDF]  

Jochen Straßner, Andreas Fürholz, Peter Macheroux, Nikolaus Amrhein, and Andreas Schaller

A Homolog of Old Yellow Enzyme in Tomato. SPECTRAL PROPERTIES AND SUBSTRATE SPECIFICITY OF THE RECOMBINANT PROTEIN
J. Biol. Chem. 1999 274: 35067-35073. [Abstract] [Full Text] [PDF]  

David A. Zapata, Alberto Pacheco-Castro, Pilar S. Torres, Almudena R. Ramiro, Ester San José, Balbino Alarcón, Laeticia Alibaud, Bent Rubin, María L. Toribio, and José R. Regueiro

Conformational and Biochemical Differences in the TCR·CD3 Complex of CD8⁺ Versus CD4⁺ Mature Lymphocytes Revealed in the Absence of CD3
J. Biol. Chem. 1999 274: 35119-35128. [Abstract] [Full Text] [PDF]  

Hideaki Itoh, Atsushi Komatsuda, Hideki Wakui, Akira B. Miura, and Yohtalou Tashima

Mammalian HSP60 Is a Major Target for an Immunosuppressant Mizoribine
J. Biol. Chem. 1999 274: 35147-35151. [Abstract] [Full Text] [PDF]  

Wei-Lih Lee, E. Michael Ostap, Henry G. Zot, and Thomas D. Pollard

Organization and Ligand Binding Properties of the Tail of Acanthamoeba Myosin-IA. IDENTIFICATION OF AN ACTIN-BINDING SITE IN THE BASIC (TAIL HOMOLOGY-1) DOMAIN
J. Biol. Chem. 1999 274: 35159-35171. [Abstract] [Full Text] [PDF]  

Kelly L. Jordan-Sciutto, Joanna M. Dragich, James L. Rhodes, and Robert Bowser

Fetal Alz-50 Clone 1, a Novel Zinc Finger Protein, Binds a Specific DNA Sequence and Acts as a Transcriptional Regulator
J. Biol. Chem. 1999 274: 35262-35268. [Abstract] [Full Text] [PDF]  

Additions and Corrections

Jianming Yu and Marianne Wessling-Resnick

Influence of copper depletion on iron uptake mediated by SFT, a stimulator of Fe transport.
J. Biol. Chem. 1999 274: 35283. [Full Text] [PDF]  

Alessandro Bianchi and Titia de Lange

Ku binds telomeric DNA in vitro.
J. Biol. Chem. 1999 274: 35284. [Full Text] [PDF]  

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