JBC -- Table of Contents (Apr 21 2000, 275, (16))

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Accelerated Publications:

Kwang-Hwan Jhee, Peter McPhie, and Edith Wilson Miles: Yeast Cystathionine $beta$ -Synthase Is a Pyridoxal Phosphate Enzyme but, Unlike the Human Enzyme, Is Not a Heme Protein
J. Biol. Chem. 2000 275: 11541-11544. First Published on March 9, 2000; doi:10.1074/jbc.C000056200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Grigory L. Dianov, Tanja Thybo, Irina I. Dianova, Leonora J. Lipinski, and Vilhelm A. Bohr: Single Nucleotide Patch Base Excision Repair Is the Major Pathway for Removal of Thymine Glycol from DNA in Human Cell Extracts
J. Biol. Chem. 2000 275: 11809-11813. First Published ; doi:10.1074/jbc.275.16.11809 [Abstract] [Full Text] [PDF]

Shinji Yasuhira and Akira Yasui: Alternative Excision Repair Pathway of UV-damaged DNA in Schizosaccharomyces pombe Operates Both in Nucleus and in Mitochondria
J. Biol. Chem. 2000 275: 11824-11828. First Published ; doi:10.1074/jbc.275.16.11824 [Abstract] [Full Text] [PDF]

Marie-Hélène David-Cordonnier, Jacques Laval, and Peter O'Neill: Clustered DNA Damage, Influence on Damage Excision by XRS5 Nuclear Extracts and Escherichia coli Nth and Fpg Proteins
J. Biol. Chem. 2000 275: 11865-11873. First Published ; doi:10.1074/jbc.275.16.11865 [Abstract] [Full Text] [PDF]

Deana A. Arnold and Stephen C. Kowalczykowski: Facilitated Loading of RecA Protein Is Essential to Recombination by RecBCD Enzyme
J. Biol. Chem. 2000 275: 12261-12265. First Published ; doi:10.1074/jbc.275.16.12261 [Abstract] [Full Text] [PDF]

Kenichi Miyako, Chihiro Takamatsu, Shuyo Umeda, Tatsurou Tajiri, Masato Furuichi, Yusaku Nakabeppu, Mutsuo Sekiguchi, Naotaka Hamasaki, Koichiro Takeshige, and Dongchon Kang: Accumulation of Adenine DNA Glycosylase-sensitive Sites in Human Mitochondrial DNA
J. Biol. Chem. 2000 275: 12326-12330. First Published ; doi:10.1074/jbc.275.16.12326 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Laurie A. Boyer, Xiao Shao, Richard H. Ebright, and Craig L. Peterson: Roles of the Histone H2A-H2B Dimers and the (H3-H4)₂ Tetramer in Nucleosome Remodeling by the SWI-SNF Complex
J. Biol. Chem. 2000 275: 11545-11552. First Published ; doi:10.1074/jbc.275.16.11545 [Abstract] [Full Text] [PDF]

Thierry Douki, Magali Court, Sylvie Sauvaigo, Francette Odin, and Jean Cadet: Formation of the Main UV-induced Thymine Dimeric Lesions within Isolated and Cellular DNA as Measured by High Performance Liquid Chromatography-Tandem Mass Spectrometry
J. Biol. Chem. 2000 275: 11678-11685. First Published ; doi:10.1074/jbc.275.16.11678 [Abstract] [Full Text] [PDF]

Xiaoyuan He, Thomas Hohn, and Johannes Fütterer: Transcriptional Activation of the Rice Tungro Bacilliform Virus Gene Is Critically Dependent on an Activator Element Located Immediately Upstream of the TATA Box
J. Biol. Chem. 2000 275: 11799-11808. First Published ; doi:10.1074/jbc.275.16.11799 [Abstract] [Full Text] [PDF]

Jie Liu, Xuening Shen, Van-Anh Nguyen, George Kunos, and Bin Gao: $alpha$ ₁ Adrenergic Agonist Induction of p21^waf1/cip1 mRNA Stability in Transfected HepG2 Cells Correlates with the Increased Binding of an AU-rich Element Binding Factor
J. Biol. Chem. 2000 275: 11846-11851. First Published ; doi:10.1074/jbc.275.16.11846 [Abstract] [Full Text] [PDF]

Robert Harrod, Yu-Liang Kuo, Yong Tang, Yao Yao, Alex Vassilev, Yoshihiro Nakatani, and Chou-Zen Giam: p300 and p300/cAMP-responsive Element-binding Protein Associated Factor Interact with Human T-cell Lymphotropic Virus Type-1 Tax in a Multi-histone Acetyltransferase/Activator-Enhancer Complex
J. Biol. Chem. 2000 275: 11852-11857. First Published ; doi:10.1074/jbc.275.16.11852 [Abstract] [Full Text] [PDF]

Laurent Beck and Daniel Markovich: The Mouse Na⁺-Sulfate Cotransporter Gene Nas1. CLONING, TISSUE DISTRIBUTION, GENE STRUCTURE, CHROMOSOMAL ASSIGNMENT, AND TRANSCRIPTIONAL REGULATION BY VITAMIN D
J. Biol. Chem. 2000 275: 11880-11890. First Published ; doi:10.1074/jbc.275.16.11880 [Abstract] [Full Text] [PDF]

George M. Yousef, Albert Chang, and Eleftherios P. Diamandis: Identification and Characterization of KLK-L4, a New Kallikrein-like Gene That Appears to be Down-regulated in Breast Cancer Tissues
J. Biol. Chem. 2000 275: 11891-11898. First Published ; doi:10.1074/jbc.275.16.11891 [Abstract] [Full Text] [PDF]

Katsuro Iwase, Kei Miyanaka, Atsuko Shimizu, Akitoshi Nagasaki, Tomomi Gotoh, Masataka Mori, and Masaki Takiguchi: Induction of Endothelial Nitric-oxide Synthase in Rat Brain Astrocytes by Systemic Lipopolysaccharide Treatment
J. Biol. Chem. 2000 275: 11929-11933. First Published ; doi:10.1074/jbc.275.16.11929 [Abstract] [Full Text] [PDF]

Karin L. Meibom, Birgitte H. Kallipolitis, Richard H. Ebright, and Poul Valentin-Hansen: Identification of the Subunit of cAMP Receptor Protein (CRP) That Functionally Interacts with CytR in CRP-CytR-mediated Transcriptional Repression
J. Biol. Chem. 2000 275: 11951-11956. First Published ; doi:10.1074/jbc.275.16.11951 [Abstract] [Full Text] [PDF]

Bridget C. Coughlin, Santuza M. R. Teixeira, Louis V. Kirchhoff, and John E. Donelson: Amastin mRNA Abundance in Trypanosoma cruzi Is Controlled by a 3'-Untranslated Region Position-dependent cis-Element and an Untranslated Region-binding Protein
J. Biol. Chem. 2000 275: 12051-12060. First Published ; doi:10.1074/jbc.275.16.12051 [Abstract] [Full Text] [PDF]

Ryan S. Streeper, Christina A. Svitek, Joshua K. Goldman, and Richard M. O'Brien: Differential Role of Hepatocyte Nuclear Factor-1 in the Regulation of Glucose-6-phosphatase Catalytic Subunit Gene Transcription by cAMP in Liver- and Kidney-derived Cell Lines
J. Biol. Chem. 2000 275: 12108-12118. First Published ; doi:10.1074/jbc.275.16.12108 [Abstract] [Full Text] [PDF]

Bart J. A. M. Jordi and Christopher F. Higgins: The Downstream Regulatory Element of the proU Operon of Salmonella typhimurium Inhibits Open Complex Formation by RNA Polymerase at a Distance
J. Biol. Chem. 2000 275: 12123-12128. First Published ; doi:10.1074/jbc.275.16.12123 [Abstract] [Full Text] [PDF]

Chris A. Learn, Steven B. Mizel, and Charles E. McCall: mRNA and Protein Stability Regulate the Differential Expression of Pro- and Anti-inflammatory Genes in Endotoxin-tolerant THP-1 Cells
J. Biol. Chem. 2000 275: 12185-12193. First Published ; doi:10.1074/jbc.275.16.12185 [Abstract] [Full Text] [PDF]

Abel Ferrández, José Luis García, and Eduardo Díaz: Transcriptional Regulation of the Divergent paa Catabolic Operons for Phenylacetic Acid Degradation in Escherichia coli
J. Biol. Chem. 2000 275: 12214-12222. First Published ; doi:10.1074/jbc.275.16.12214 [Abstract] [Full Text] [PDF]

Yu Liu, Xiaohong Zhong, Wenhui Li, Michael G. Brattain, and Sunandita S. Banerji: The Role of Sp1 in the Differential Expression of Transforming Growth Factor- $beta$ Receptor Type II in Human Breast Adenocarcinoma MCF-7 Cells
J. Biol. Chem. 2000 275: 12231-12236. First Published ; doi:10.1074/jbc.275.16.12231 [Abstract] [Full Text] [PDF]

Erik Schoenmakers, Guy Verrijdt, Ben Peeters, Guido Verhoeven, Wilfried Rombauts, and Frank Claessens: Differences in DNA Binding Characteristics of the Androgen and Glucocorticoid Receptors Can Determine Hormone-specific Responses
J. Biol. Chem. 2000 275: 12290-12297. First Published ; doi:10.1074/jbc.275.16.12290 [Abstract] [Full Text] [PDF]

Guy Verrijdt, Erik Schoenmakers, Annemie Haelens, Ben Peeters, Guido Verhoeven, Wilfried Rombauts, and Frank Claessens: Change of Specificity Mutations in Androgen-selective Enhancers. EVIDENCE FOR A ROLE OF DIFFERENTIAL DNA BINDING BY THE ANDROGEN RECEPTOR
J. Biol. Chem. 2000 275: 12298-12305. First Published ; doi:10.1074/jbc.275.16.12298 [Abstract] [Full Text] [PDF]

Chien-Fu Huang, Yeau-Ching Wang, Der-An Tsao, Shiu-Feng Tung, Young-Sun Lin, and Cheng-Wen Wu: Antagonism between Members of the CNC-bZIP Family and the Immediate-Early Protein IE2 of Human Cytomegalovirus
J. Biol. Chem. 2000 275: 12313-12320. First Published ; doi:10.1074/jbc.275.16.12313 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Peter Askjaer, Rita Rosendahl, and Jørgen Kjems: Nuclear Export of the DEAD Box An3 Protein by CRM1 Is Coupled to An3 Helicase Activity
J. Biol. Chem. 2000 275: 11561-11568. First Published ; doi:10.1074/jbc.275.16.11561 [Abstract] [Full Text] [PDF]

Alessio Peracchi: Preferential Activation of the 8-17 Deoxyribozyme by Ca²⁺ Ions. EVIDENCE FOR THE IDENTITY OF 8-17 WITH THE CATALYTIC DOMAIN OF THE MG5 DEOXYRIBOZYME
J. Biol. Chem. 2000 275: 11693-11697. First Published ; doi:10.1074/jbc.275.16.11693 [Abstract] [Full Text] [PDF]

Dan A. Dixon, Craig D. Kaplan, Thomas M. McIntyre, Guy A. Zimmerman, and Stephen M. Prescott: Post-transcriptional Control of Cyclooxygenase-2 Gene Expression. THE ROLE OF THE 3'-UNTRANSLATED REGION
J. Biol. Chem. 2000 275: 11750-11757. First Published ; doi:10.1074/jbc.275.16.11750 [Abstract] [Full Text] [PDF]

Jean-Marc Lanchy, Catherine Isel, Gérard Keith, Stuart F. J. Le Grice, Chantal Ehresmann, Bernard Ehresmann, and Roland Marquet: Dynamics of the HIV-1 Reverse Transcription Complex during Initiation of DNA Synthesis
J. Biol. Chem. 2000 275: 12306-12312. First Published ; doi:10.1074/jbc.275.16.12306 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Jinhua Feng, David L. Smith, and Jean B. Smith: Human Lens $beta$ -Crystallin Solubility
J. Biol. Chem. 2000 275: 11585-11590. First Published ; doi:10.1074/jbc.275.16.11585 [Abstract] [Full Text] [PDF]

Julie Soutourina, Sylvain Blanquet, and Pierre Plateau: D-Tyrosyl-tRNA^Tyr Metabolism in Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 11626-11630. First Published ; doi:10.1074/jbc.275.16.11626 [Abstract] [Full Text] [PDF]

Theophile Ohlmann, Marcelo Lopez-Lastra, and Jean-Luc Darlix: An Internal Ribosome Entry Segment Promotes Translation of the Simian Immunodeficiency Virus Genomic RNA
J. Biol. Chem. 2000 275: 11899-11906. First Published ; doi:10.1074/jbc.275.16.11899 [Abstract] [Full Text] [PDF]

Doris Germain, Adrian Russell, Anne Thompson, and Joy Hendley: Ubiquitination of Free Cyclin D1 Is Independent of Phosphorylation on Threonine 286
J. Biol. Chem. 2000 275: 12074-12079. First Published ; doi:10.1074/jbc.275.16.12074 [Abstract] [Full Text] [PDF]

Takanori Muto, Michael D. Feese, Yoshihiro Shimada, Youko Kudou, Tomoyuki Okamoto, Tadashi Ozawa, Tomoyuki Tahara, Hideya Ohashi, Kinya Ogami, Takashi Kato, Hiroshi Miyazaki, and Ryota Kuroki: Functional Analysis of the C-terminal Region of Recombinant Human Thrombopoietin. C-TERMINAL REGION OF THROMBOPOIETIN IS A "SHUTTLE" PEPTIDE TO HELP SECRETION
J. Biol. Chem. 2000 275: 12090-12094. First Published ; doi:10.1074/jbc.275.16.12090 [Abstract] [Full Text] [PDF]

Joanne F. Berson, David W. Frank, Paul A. Calvo, Bert M. Bieler, and Michael S. Marks: A Common Temperature-sensitive Allelic Form of Human Tyrosinase Is Retained in the Endoplasmic Reticulum at the Nonpermissive Temperature
J. Biol. Chem. 2000 275: 12281-12289. First Published ; doi:10.1074/jbc.275.16.12281 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Marco G. Casarotto, Frank Gibson, Suzi M. Pace, Suzanne M. Curtis, Mark Mulcair, and Angela F. Dulhunty: A Structural Requirement for Activation of Skeletal Ryanodine Receptors by Peptides of the Dihydropyridine Receptor II-III Loop
J. Biol. Chem. 2000 275: 11631-11637. First Published ; doi:10.1074/jbc.275.16.11631 [Abstract] [Full Text] [PDF]

Sabine Frank, Ariel Lustig, Therese Schulthess, Jürgen Engel, and Richard A. Kammerer: A Distinct Seven-residue Trigger Sequence Is Indispensable for Proper Coiled-coil Formation of the Human Macrophage Scavenger Receptor Oligomerization Domain
J. Biol. Chem. 2000 275: 11672-11677. First Published ; doi:10.1074/jbc.275.16.11672 [Abstract] [Full Text] [PDF]

David J. J. Waugh, Ming-Ming Zhao, Michael J. Zuscik, and Dianne M. Perez: Novel Aromatic Residues in Transmembrane Domains IV and V Involved in Agonist Binding at $alpha$ _1a-Adrenergic Receptors
J. Biol. Chem. 2000 275: 11698-11705. First Published ; doi:10.1074/jbc.275.16.11698 [Abstract] [Full Text] [PDF]

Germán Rivas, Asunción López, Jesús Mingorance, María José Ferrándiz, Silvia Zorrilla, Allen P. Minton, Miguel Vicente, and José Manuel Andreu: Magnesium-induced Linear Self-association of the FtsZ Bacterial Cell Division Protein Monomer. THE PRIMARY STEPS FOR FtsZ ASSEMBLY
J. Biol. Chem. 2000 275: 11740-11749. First Published ; doi:10.1074/jbc.275.16.11740 [Abstract] [Full Text] [PDF]

Vinod Singh and Wolfgang E. Merz: Disulfide Bond Formation Is Not Required for Human Chorionic Gonadotropin Subunit Association. STUDIES WITH DITHIOTHREITOL IN JEG-3 CELLS
J. Biol. Chem. 2000 275: 11765-11770. First Published ; doi:10.1074/jbc.275.16.11765 [Abstract] [Full Text] [PDF]

Sergey N. Fedosov, Natalya U. Fedosova, Ebba Nexø, and Torben E. Petersen: Conformational Changes of Transcobalamin Induced by Aquocobalamin Binding. MECHANISM OF SUBSTITUTION OF THE COBALT-COORDINATED GROUP IN THE BOUND LIGAND
J. Biol. Chem. 2000 275: 11791-11798. First Published ; doi:10.1074/jbc.275.16.11791 [Abstract] [Full Text] [PDF]

Ramona Dickson, Celeste Weiss, Richard J. Howard, Sharon P. Alldrick, R. John Ellis, George Lorimer, Abdussalam Azem, and Paul V. Viitanen: Reconstitution of Higher Plant Chloroplast Chaperonin 60 Tetradecamers Active in Protein Folding
J. Biol. Chem. 2000 275: 11829-11835. First Published ; doi:10.1074/jbc.275.16.11829 [Abstract] [Full Text] [PDF]

Klara Ösapay, Dat Tran, Alexey S. Ladokhin, Stephen H. White, Agnes H. Henschen, and Michael E. Selsted: Formation and Characterization of a Single Trp-Trp Cross-link in Indolicidin That Confers Protease Stability without Altering Antimicrobial Activity
J. Biol. Chem. 2000 275: 12017-12022. First Published ; doi:10.1074/jbc.275.16.12017 [Abstract] [Full Text] [PDF]

Yael Kenan, Taku Murata, Yasmin Shakur, Eva Degerman, and Vincent C. Manganiello: Functions of the N-terminal Region of Cyclic Nucleotide Phosphodiesterase 3 (PDE 3) Isoforms
J. Biol. Chem. 2000 275: 12331-12338. First Published ; doi:10.1074/jbc.275.16.12331 [Abstract] [Full Text] [PDF]

Dieter P. Reinhardt, Robert N. Ono, Holger Notbohm, Peter K. Müller, Hans Peter Bächinger, and Lynn Y. Sakai: Mutations in Calcium-binding Epidermal Growth Factor Modules Render Fibrillin-1 Susceptible to Proteolysis. A POTENTIAL DISEASE-CAUSING MECHANISM IN MARFAN SYNDROME
J. Biol. Chem. 2000 275: 12339-12345. First Published ; doi:10.1074/jbc.275.16.12339 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Henry A. Charlier, Jr. and Bryce V. Plapp: Kinetic Cooperativity of Human Liver Alcohol Dehydrogenase $gamma$ ₂
J. Biol. Chem. 2000 275: 11569-11575. First Published ; doi:10.1074/jbc.275.16.11569 [Abstract] [Full Text] [PDF]

Véronique Marcel, Sandino Estrada-Mondaca, Frédéric Magné, Jure Stojan, Alain Klaébé, and Didier Fournier: Exploration of the Drosophila Acetylcholinesterase Substrate Activation Site Using a Reversible Inhibitor (Triton X-100) and Mutated Enzymes
J. Biol. Chem. 2000 275: 11603-11609. First Published ; doi:10.1074/jbc.275.16.11603 [Abstract] [Full Text] [PDF]

Christine J. van Dalen, Christine C. Winterbourn, Revathy Senthilmohan, and Anthony J. Kettle: Nitrite as a Substrate and Inhibitor of Myeloperoxidase. IMPLICATIONS FOR NITRATION AND HYPOCHLOROUS ACID PRODUCTION AT SITES OF INFLAMMATION
J. Biol. Chem. 2000 275: 11638-11644. First Published ; doi:10.1074/jbc.275.16.11638 [Abstract] [Full Text] [PDF]

Rokus Renirie, Wieger Hemrika, and Ron Wever: Peroxidase and Phosphatase Activity of Active-site Mutants of Vanadium Chloroperoxidase from the Fungus Curvularia inaequalis. IMPLICATIONS FOR THE CATALYTIC MECHANISMS
J. Biol. Chem. 2000 275: 11650-11657. First Published ; doi:10.1074/jbc.275.16.11650 [Abstract] [Full Text] [PDF]

Angela Wilks and Pierre Moënne-Loccoz: Identification of the Proximal Ligand His-20 in Heme Oxygenase (Hmu O) from Corynebacterium diphtheriae. OXIDATIVE CLEAVAGE OF THE HEME MACROCYCLE DOES NOT REQUIRE THE PROXIMAL HISTIDINE
J. Biol. Chem. 2000 275: 11686-11692. First Published ; doi:10.1074/jbc.275.16.11686 [Abstract] [Full Text] [PDF]

Luis M. Quirós, Rodrigo J. Carbajo, Alfredo F. Braña, and José A. Salas: Glycosylation of Macrolide Antibiotics. PURIFICATION AND KINETIC STUDIES OF A MACROLIDE GLYCOSYLTRANSFERASE FROM STREPTOMYCES ANTIBIOTICUS
J. Biol. Chem. 2000 275: 11713-11720. First Published ; doi:10.1074/jbc.275.16.11713 [Abstract] [Full Text] [PDF]

John P. Plastaras, F. Peter Guengerich, Daniel W. Nebert, and Lawrence J. Marnett: Xenobiotic-metabolizing Cytochromes P450 Convert Prostaglandin Endoperoxide to Hydroxyheptadecatrienoic Acid and the Mutagen, Malondialdehyde
J. Biol. Chem. 2000 275: 11784-11790. First Published ; doi:10.1074/jbc.275.16.11784 [Abstract] [Full Text] [PDF]

Johannes von Lintig and Klaus Vogt: Filling the Gap in Vitamin A Research. MOLECULAR IDENTIFICATION OF AN ENZYME CLEAVING $beta$ -CAROTENE TO RETINAL
J. Biol. Chem. 2000 275: 11915-11920. First Published ; doi:10.1074/jbc.275.16.11915 [Abstract] [Full Text] [PDF]

Tristan J. Fiedler, Curt A. Davey, and Roger E. Fenna: X-ray Crystal Structure and Characterization of Halide-binding Sites of Human Myeloperoxidase at 1.8 Å Resolution
J. Biol. Chem. 2000 275: 11964-11971. First Published ; doi:10.1074/jbc.275.16.11964 [Abstract] [Full Text] [PDF]

Sonia Hernandez-Barrantes, Marta Toth, M. Margarida Bernardo, Maria Yurkova, David C. Gervasi, Yuval Raz, QingXiang Amy Sang, and Rafael Fridman: Binding of Active (57 kDa) Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) to Tissue Inhibitor of Metalloproteinase (TIMP)-2 Regulates MT1-MMP Processing and Pro-MMP-2 Activation
J. Biol. Chem. 2000 275: 12080-12089. First Published ; doi:10.1074/jbc.275.16.12080 [Abstract] [Full Text] [PDF]

Françoise Paturiaux-Hanocq, Jacqueline Hanocq-Quertier, Maria Lucia Cardoso de Almeida, Derek P. Nolan, Annette Pays, Luc Vanhamme, Jan Van den Abbeele, Christine L. Wasunna, Mark Carrington, and Etienne Pays: A Role for the Dynamic Acylation of a Cluster of Cysteine Residues in Regulating the Activity of the Glycosylphosphatidylinositol-specific Phospholipase C of Trypanosoma brucei
J. Biol. Chem. 2000 275: 12147-12155. First Published ; doi:10.1074/jbc.275.16.12147 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Jeane M. De Freitas, Amir Liba, Rogerio Meneghini, Joan Selverstone Valentine, and Edith Butler Gralla: Yeast Lacking Cu-Zn Superoxide Dismutase Show Altered Iron Homeostasis. ROLE OF OXIDATIVE STRESS IN IRON METABOLISM
J. Biol. Chem. 2000 275: 11645-11649. First Published ; doi:10.1074/jbc.275.16.11645 [Abstract] [Full Text] [PDF]

Graciela B. Sala-Newby, Nicola V. E. Freeman, Andrzej C. Skladanowski, and Andrew C. Newby: Distinct Roles for Recombinant Cytosolic 5'-Nucleotidase-I and -II in AMP and IMP Catabolism in COS-7 and H9c2 Rat Myoblast Cell Lines
J. Biol. Chem. 2000 275: 11666-11671. First Published ; doi:10.1074/jbc.275.16.11666 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Simi Ali, Adrian C. V. Palmer, Ben Banerjee, Sarah J. Fritchley, and John A. Kirby: Examination of the Function of RANTES, MIP-1 $alpha$ , and MIP-1 $beta$ following Interaction with Heparin-like Glycosaminoglycans
J. Biol. Chem. 2000 275: 11721-11727. First Published ; doi:10.1074/jbc.275.16.11721 [Abstract] [Full Text] [PDF]

Shih-Houng Young, Wen-Ji Dong, and Robert R. Jacobs: Observation of a Partially Opened Triple-helix Conformation in 1 $right-arrow$ 3- $beta$ -Glucan by Fluorescence Resonance Energy Transfer Spectroscopy
J. Biol. Chem. 2000 275: 11874-11879. First Published ; doi:10.1074/jbc.275.16.11874 [Abstract] [Full Text] [PDF]

Marcus Mreyen, Alan Champion, Supriya Srinivasan, Peter Karuso, Keith L. Williams, and Nicolle H. Packer: Multiple O-Glycoforms on the Spore Coat Protein SP96 in Dictyostelium discoideum. Fuc( $alpha$ 1-3)GlcNAc- $alpha$ -1-P-Ser IS THE MAJOR MODIFICATION
J. Biol. Chem. 2000 275: 12164-12174. First Published ; doi:10.1074/jbc.275.16.12164 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Samar M. Hammad, Jeremy L. Barth, Christian Knaak, and W. Scott Argraves: Megalin Acts in Concert with Cubilin to Mediate Endocytosis of High Density Lipoproteins
J. Biol. Chem. 2000 275: 12003-12008. First Published ; doi:10.1074/jbc.275.16.12003 [Abstract] [Full Text] [PDF]

Mary G. Sorci-Thomas, Mike Thomas, Linda Curtiss, and Mark Landrum: Single Repeat Deletion in ApoA-I Blocks Cholesterol Esterification and Results in Rapid Catabolism of $Delta$ 6 and Wild-type ApoA-I in Transgenic Mice
J. Biol. Chem. 2000 275: 12156-12163. First Published ; doi:10.1074/jbc.275.16.12156 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Nicola R. Stanley, Tracy Palmer, and Ben C. Berks: The Twin Arginine Consensus Motif of Tat Signal Peptides Is Involved in Sec-independent Protein Targeting in Escherichia coli
J. Biol. Chem. 2000 275: 11591-11596. First Published ; doi:10.1074/jbc.275.16.11591 [Abstract] [Full Text] [PDF]

Danqing Li, Koichi Takimoto, and Edwin S. Levitan: Surface Expression of Kv1 Channels Is Governed by a C-terminal Motif
J. Biol. Chem. 2000 275: 11597-11602. First Published ; doi:10.1074/jbc.275.16.11597 [Abstract] [Full Text] [PDF]

Takeshi Yamamoto, Roque El-Hayek, and Noriaki Ikemoto: Postulated Role of Interdomain Interaction within the Ryanodine Receptor in Ca²⁺ Channel Regulation
J. Biol. Chem. 2000 275: 11618-11625. First Published ; doi:10.1074/jbc.275.16.11618 [Abstract] [Full Text] [PDF]

Alessandro Prinetti, Vanna Chigorno, Guido Tettamanti, and Sandro Sonnino: Sphingolipid-enriched Membrane Domains from Rat Cerebellar Granule Cells Differentiated in Culture. A COMPOSITIONAL STUDY
J. Biol. Chem. 2000 275: 11658-11665. First Published ; doi:10.1074/jbc.275.16.11658 [Abstract] [Full Text] [PDF]

Thomas Steinkamp, Kerstin Hill, Silke C. Hinnah, Richard Wagner, Thomas Röhl, Kai Pohlmeyer, and Jürgen Soll: Identification of the Pore-forming Region of the Outer Chloroplast Envelope Protein OEP16
J. Biol. Chem. 2000 275: 11758-11764. First Published ; doi:10.1074/jbc.275.16.11758 [Abstract] [Full Text] [PDF]

Patrick R. D'Silva and Anil K. Lala: Organization of Diphtheria Toxin in Membranes. A HYDROPHOBIC PHOTOLABELING STUDY
J. Biol. Chem. 2000 275: 11771-11777. First Published ; doi:10.1074/jbc.275.16.11771 [Abstract] [Full Text] [PDF]

Guo Guang Du, Vijay K. Khanna, and David H. MacLennan: Mutation of Divergent Region 1 Alters Caffeine and Ca²⁺ Sensitivity of the Skeletal Muscle Ca²⁺ Release Channel (Ryanodine Receptor)
J. Biol. Chem. 2000 275: 11778-11783. First Published ; doi:10.1074/jbc.275.16.11778 [Abstract] [Full Text] [PDF]

Andrew S. Opat, Fiona Houghton, and Paul A. Gleeson: Medial Golgi but Not Late Golgi Glycosyltransferases Exist as High Molecular Weight Complexes. ROLE OF LUMINAL DOMAIN IN COMPLEX FORMATION AND LOCALIZATION
J. Biol. Chem. 2000 275: 11836-11845. First Published ; doi:10.1074/jbc.275.16.11836 [Abstract] [Full Text] [PDF]

Haiyan Tong, Weina Chen, Robert E. London, Elizabeth Murphy, and Charles Steenbergen: Preconditioning Enhanced Glucose Uptake Is Mediated by p38 MAP Kinase Not by Phosphatidylinositol 3-Kinase
J. Biol. Chem. 2000 275: 11981-11986. First Published ; doi:10.1074/jbc.275.16.11981 [Abstract] [Full Text] [PDF]

Ronald S. Kaplan, June A. Mayor, David Brauer, Rusudan Kotaria, D. Eric Walters, and Antony M. Dean: The Yeast Mitochondrial Citrate Transport Protein. PROBING THE SECONDARY STRUCTURE OF TRANSMEMBRANE DOMAIN IV AND IDENTIFICATION OF RESIDUES THAT LIKELY COMPRISE A PORTION OF THE CITRATE TRANSLOCATION PATHWAY
J. Biol. Chem. 2000 275: 12009-12016. First Published ; doi:10.1074/jbc.275.16.12009 [Abstract] [Full Text] [PDF]

Anirban Siddhanta, Jonathan M. Backer, and Dennis Shields: Inhibition of Phosphatidic Acid Synthesis Alters the Structure of the Golgi Apparatus and Inhibits Secretion in Endocrine Cells
J. Biol. Chem. 2000 275: 12023-12031. First Published ; doi:10.1074/jbc.275.16.12023 [Abstract] [Full Text] [PDF]

Jianying Liu, Xugang Qiao, Dongyi Du, and Mary Gwo-Shu Lee: Receptor-mediated Endocytosis in the Procyclic Form of Trypanosoma brucei
J. Biol. Chem. 2000 275: 12032-12040. First Published ; doi:10.1074/jbc.275.16.12032 [Abstract] [Full Text] [PDF]

Angela G. Brittsan, Andrew N. Carr, Albrecht G. Schmidt, and Evangelia G. Kranias: Maximal Inhibition of SERCA2 Ca²⁺ Affinity by Phospholamban in Transgenic Hearts Overexpressing a Non-phosphorylatable Form of Phospholamban
J. Biol. Chem. 2000 275: 12129-12135. First Published ; doi:10.1074/jbc.275.16.12129 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Andrew Giovanni, Elizabeth Keramaris, Erick J. Morris, Sheng T. Hou, Michael O'Hare, Nick Dyson, George S. Robertson, Ruth S. Slack, and David S. Park: E2F1 Mediates Death of B-amyloid-treated Cortical Neurons in a Manner Independent of p53 and Dependent on Bax and Caspase 3
J. Biol. Chem. 2000 275: 11553-11560. First Published ; doi:10.1074/jbc.275.16.11553 [Abstract] [Full Text] [PDF]

Dora Bigler, Yuji Takahashi, Michellee S. Chen, Eduardo A. C. Almeida, Laurie Osbourne, and Judith M. White: Sequence-specific Interaction between the Disintegrin Domain of Mouse ADAM 2 (Fertilin $beta$ ) and Murine Eggs. ROLE OF THE $alpha$ ₆ INTEGRIN SUBUNIT
J. Biol. Chem. 2000 275: 11576-11584. First Published ; doi:10.1074/jbc.275.16.11576 [Abstract] [Full Text] [PDF]

Kate A. Powell, Valentina A. Valova, Chandra S. Malladi, Ole N. Jensen, Martin R. Larsen, and Phillip J. Robinson: Phosphorylation of Dynamin I on Ser-795 by Protein Kinase C Blocks Its Association with Phospholipids
J. Biol. Chem. 2000 275: 11610-11617. First Published ; doi:10.1074/jbc.275.16.11610 [Abstract] [Full Text] [PDF]

Jay W. Tichelaar, Wei Lu, and Jeffrey A. Whitsett: Conditional Expression of Fibroblast Growth Factor-7 in the Developing and Mature Lung
J. Biol. Chem. 2000 275: 11858-11864. First Published ; doi:10.1074/jbc.275.16.11858 [Abstract] [Full Text] [PDF]

Timothy P. Lockwich, Xibao Liu, Brij B. Singh, Julie Jadlowiec, Sharon Weiland, and Indu S. Ambudkar: Assembly of Trp1 in a Signaling Complex Associated with Caveolin-Scaffolding Lipid Raft Domains
J. Biol. Chem. 2000 275: 11934-11942. First Published ; doi:10.1074/jbc.275.16.11934 [Abstract] [Full Text] [PDF]

Kiyoshi Ariizumi, Guo-Liang Shen, Sojin Shikano, Robert Ritter, III, Paul Zukas, Dale Edelbaum, Akimichi Morita, and Akira Takashima: Cloning of a Second Dendritic Cell-associated C-type Lectin (Dectin-2) and Its Alternatively Spliced Isoforms
J. Biol. Chem. 2000 275: 11957-11963. First Published ; doi:10.1074/jbc.275.16.11957 [Abstract] [Full Text] [PDF]

Yoshifumi Banzai, Hiroaki Miki, Hideki Yamaguchi, and Tadaomi Takenawa: Essential Role of Neural Wiskott-Aldrich Syndrome Protein in Neurite Extension in PC12 Cells and Rat Hippocampal Primary Culture Cells
J. Biol. Chem. 2000 275: 11987-11992. First Published ; doi:10.1074/jbc.275.16.11987 [Abstract] [Full Text] [PDF]

Liana Adam, Ratna Vadlamudi, Mahitosh Mandal, Jonathan Chernoff, and Rakesh Kumar: Regulation of Microfilament Reorganization and Invasiveness of Breast Cancer Cells by Kinase Dead p21-activated Kinase-1
J. Biol. Chem. 2000 275: 12041-12050. First Published ; doi:10.1074/jbc.275.16.12041 [Abstract] [Full Text] [PDF]

Olaf Rosorius, Barbara Fries, Roland H. Stauber, Nicole Hirschmann, Dorian Bevec, and Joachim Hauber: Human Ribosomal Protein L5 Contains Defined Nuclear Localization and Export Signals
J. Biol. Chem. 2000 275: 12061-12068. First Published ; doi:10.1074/jbc.275.16.12061 [Abstract] [Full Text] [PDF]

Ann McGinty, Yu-Wen E. Chang, Andrey Sorokin, Dirk Bokemeyer, and Michael J. Dunn: Cyclooxygenase-2 Expression Inhibits Trophic Withdrawal Apoptosis in Nerve Growth Factor-differentiated PC12 Cells
J. Biol. Chem. 2000 275: 12095-12101. First Published ; doi:10.1074/jbc.275.16.12095 [Abstract] [Full Text] [PDF]

Morichika Konishi, Tadahisa Mikami, Masahiro Yamasaki, Ayumi Miyake, and Nobuyuki Itoh: Fibroblast Growth Factor-16 Is a Growth Factor for Embryonic Brown Adipocytes
J. Biol. Chem. 2000 275: 12119-12122. First Published ; doi:10.1074/jbc.275.16.12119 [Abstract] [Full Text] [PDF]

Lihua He, Ann T. Poblenz, Carlos J. Medrano, and Donald A. Fox: Lead and Calcium Produce Rod Photoreceptor Cell Apoptosis by Opening the Mitochondrial Permeability Transition Pore
J. Biol. Chem. 2000 275: 12175-12184. First Published ; doi:10.1074/jbc.275.16.12175 [Abstract] [Full Text] [PDF]

Boning Gao, Yoshitaka Sekido, Anton Maximov, Mohamad Saad, Eva Forgacs, Farida Latif, Ming H. Wei, Michael Lerman, Jung-Ha Lee, Edward Perez-Reyes, Ilya Bezprozvanny, and John D. Minna: Functional Properties of a New Voltage-dependent Calcium Channel $alpha$ ₂ $delta$ Auxiliary Subunit Gene (CACNA2D2)
J. Biol. Chem. 2000 275: 12237-12242. First Published ; doi:10.1074/jbc.275.16.12237 [Abstract] [Full Text] [PDF]

Yan Larry Zhou and Malcolm L. Snead: Identification of CCAAT/Enhancer-binding Protein $alpha$ as a Transactivator of the Mouse Amelogenin Gene
J. Biol. Chem. 2000 275: 12273-12280. First Published ; doi:10.1074/jbc.275.16.12273 [Abstract] [Full Text] [PDF]

Mary A. Dionne, Angela Sanchez, and Duane A. Compton: ch-TOGp Is Required for Microtubule Aster Formation in a Mammalian Mitotic Extract
J. Biol. Chem. 2000 275: 12346-12352. First Published ; doi:10.1074/jbc.275.16.12346 [Abstract] [Full Text] [PDF]

Young-Mee Yoon, Chun-Do Oh, Do-Yoon Kim, Young-Sup Lee, Jeen-Woo Park, Tae-Lin Huh, Shin-Sung Kang, and Jang-Soo Chun: Epidermal Growth Factor Negatively Regulates Chondrogenesis of Mesenchymal Cells by Modulating the Protein Kinase C- $alpha$ , Erk-1, and p38 MAPK Signaling Pathways
J. Biol. Chem. 2000 275: 12353-12359. First Published ; doi:10.1074/jbc.275.16.12353 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Masanori Yoshizumi, Jun-ichi Abe, Judith Haendeler, Qunhua Huang, and Bradford C. Berk: Src and Cas Mediate JNK Activation but Not ERK1/2 and p38 Kinases by Reactive Oxygen Species
J. Biol. Chem. 2000 275: 11706-11712. First Published ; doi:10.1074/jbc.275.16.11706 [Abstract] [Full Text] [PDF]

Koji Tokoyoda, Yoshihiro Takemoto, Toshinori Nakayama, Takao Arai, and Masato Kubo: Synergism between the Calmodulin-binding and Autoinhibitory Domains on Calcineurin Is Essential for the Induction of Their Phosphatase Activity
J. Biol. Chem. 2000 275: 11728-11734. First Published ; doi:10.1074/jbc.275.16.11728 [Abstract] [Full Text] [PDF]

Rennolds S. Ostrom, Caroline Gregorian, and Paul A. Insel: Cellular Release of and Response to ATP as Key Determinants of the Set-Point of Signal Transduction Pathways
J. Biol. Chem. 2000 275: 11735-11739. First Published ; doi:10.1074/jbc.275.16.11735 [Abstract] [Full Text] [PDF]

Etsuro Hatano, Cynthia A. Bradham, Alexander Stark, Yuji Iimuro, John J. Lemasters, and David A. Brenner: The Mitochondrial Permeability Transition Augments Fas-induced Apoptosis in Mouse Hepatocytes
J. Biol. Chem. 2000 275: 11814-11823. First Published ; doi:10.1074/jbc.275.16.11814 [Abstract] [Full Text] [PDF]

Li-Na Wei, Xinli Hu, and Chatchai Chinpaisal: Constitutive Activation of Retinoic Acid Receptor $beta$ 2 Promoter by Orphan Nuclear Receptor TR2
J. Biol. Chem. 2000 275: 11907-11914. First Published ; doi:10.1074/jbc.275.16.11907 [Abstract] [Full Text] [PDF]

Shi-Fang Yan, Jiesheng Lu, Yu Shan Zou, Walter Kisiel, Nigel Mackman, Michael Leitges, Susan Steinberg, David Pinsky, and David Stern: Protein Kinase C- $beta$ and Oxygen Deprivation. A NOVEL Egr-1-DEPENDENT PATHWAY FOR FIBRIN DEPOSITION IN HYPOXEMIC VASCULATURE
J. Biol. Chem. 2000 275: 11921-11928. First Published ; doi:10.1074/jbc.275.16.11921 [Abstract] [Full Text] [PDF]

Jan Domin, Ibragim Gaidarov, Mary E. K. Smith, James H. Keen, and Michael D. Waterfield: The Class II Phosphoinositide 3-Kinase PI3K-C2 $alpha$ Is Concentrated in the Trans-Golgi Network and Present in Clathrin-coated Vesicles
J. Biol. Chem. 2000 275: 11943-11950. First Published ; doi:10.1074/jbc.275.16.11943 [Abstract] [Full Text] [PDF]

Olav Klingenberg, Antoni Wiedlocha, Lucía Citores, and Sjur Olsnes: Requirement of Phosphatidylinositol 3-Kinase Activity for Translocation of Exogenous aFGF to the Cytosol and Nucleus
J. Biol. Chem. 2000 275: 11972-11980. First Published ; doi:10.1074/jbc.275.16.11972 [Abstract] [Full Text] [PDF]

Meenakshi A. Chellaiah, Norihito Soga, Suzanne Swanson, Sandy McAllister, Ulises Alvarez, Dongmei Wang, Steven F. Dowdy, and Keith A. Hruska: Rho-A Is Critical for Osteoclast Podosome Organization, Motility, and Bone Resorption
J. Biol. Chem. 2000 275: 11993-12002. First Published ; doi:10.1074/jbc.275.16.11993 [Abstract] [Full Text] [PDF]

Cristina Murga, Shigetomo Fukuhara, and J. Silvio Gutkind: A Novel Role for Phosphatidylinositol 3-Kinase $beta$ in Signaling from G Protein-coupled Receptors to Akt
J. Biol. Chem. 2000 275: 12069-12073. First Published ; doi:10.1074/jbc.275.16.12069 [Abstract] [Full Text] [PDF]

Juan M. Zapata, Shu-ichi Matsuzawa, Adam Godzik, Eugen Leo, Steven A. Wasserman, and John C. Reed: The Drosophila Tumor Necrosis Factor Receptor-associated Factor-1 (DTRAF1) Interacts with Pelle and Regulates NF $kappa$ B Activity
J. Biol. Chem. 2000 275: 12102-12107. First Published ; doi:10.1074/jbc.275.16.12102 [Abstract] [Full Text] [PDF]

Qiming J. Wang, Tzan-Wei Fang, David Fenick, Susan Garfield, Bruno Bienfait, Victor E. Marquez, and Peter M. Blumberg: The Lipophilicity of Phorbol Esters as a Critical Factor in Determining the Pattern of Translocation of Protein Kinase C $delta$ Fused to Green Fluorescent Protein
J. Biol. Chem. 2000 275: 12136-12146. First Published ; doi:10.1074/jbc.275.16.12136 [Abstract] [Full Text] [PDF]

Mingya Liu, Lisan L. Parker, Brian E. Wadzinski, and Bih-Hwa Shieh: Reversible Phosphorylation of the Signal Transduction Complex in Drosophila Photoreceptors
J. Biol. Chem. 2000 275: 12194-12199. First Published ; doi:10.1074/jbc.275.16.12194 [Abstract] [Full Text] [PDF]

Madalina Stanciu, Ying Wang, Ruth Kentor, Nancy Burke, Simon Watkins, Geraldine Kress, Ian Reynolds, Eric Klann, Maria R. Angiolieri, Jon W. Johnson, and Donald B. DeFranco: Persistent Activation of ERK Contributes to Glutamate-induced Oxidative Toxicity in a Neuronal Cell Line and Primary Cortical Neuron Cultures
J. Biol. Chem. 2000 275: 12200-12206. First Published ; doi:10.1074/jbc.275.16.12200 [Abstract] [Full Text] [PDF]

Ulrich Böcker, Arndt Schottelius, Joanna M. Watson, Lisa Holt, Laura L. Licato, David A. Brenner, R. Balfour Sartor, and Christian Jobin: Cellular Differentiation Causes a Selective Down-regulation of Interleukin (IL)-1 $beta$ -mediated NF- $kappa$ B Activation and IL-8 Gene Expression in Intestinal Epithelial Cells
J. Biol. Chem. 2000 275: 12207-12213. First Published ; doi:10.1074/jbc.275.16.12207 [Abstract] [Full Text] [PDF]

Deming Wang, Xin Yu, Richard A. Cohen, and Peter Brecher: Distinct Effects of N-Acetylcysteine and Nitric Oxide on Angiotensin II-induced Epidermal Growth Factor Receptor Phosphorylation and Intracellular Ca²⁺ Levels
J. Biol. Chem. 2000 275: 12223-12230. First Published ; doi:10.1074/jbc.275.16.12223 [Abstract] [Full Text] [PDF]

Karim Bordji, Joël-Paul Grillasca, Jean-Noël Gouze, Jacques Magdalou, Hervé Schohn, Jean-Marie Keller, Arnaud Bianchi, Michel Dauça, Patrick Netter, and Bernard Terlain: Evidence for the Presence of Peroxisome Proliferator-activated Receptor (PPAR) $alpha$ and $gamma$ and Retinoid Z Receptor in Cartilage. PPAR $gamma$ ACTIVATION MODULATES THE EFFECTS OF INTERLEUKIN-1 $beta$ ON RAT CHONDROCYTES
J. Biol. Chem. 2000 275: 12243-12250. First Published ; doi:10.1074/jbc.275.16.12243 [Abstract] [Full Text] [PDF]

Robert Grosse, Susanne Roelle, Andreas Herrlich, Julia Höhn, and Thomas Gudermann: Epidermal Growth Factor Receptor Tyrosine Kinase Mediates Ras Activation by Gonadotropin-releasing Hormone
J. Biol. Chem. 2000 275: 12251-12260. First Published ; doi:10.1074/jbc.275.16.12251 [Abstract] [Full Text] [PDF]

Shuang Huang, Liguo New, Zhixing Pan, Jiahuai Han, and Glen R. Nemerow: Urokinase Plasminogen Activator/Urokinase-specific Surface Receptor Expression and Matrix Invasion by Breast Cancer Cells Requires Constitutive p38 $alpha$ Mitogen-activated Protein Kinase Activity
J. Biol. Chem. 2000 275: 12266-12272. First Published ; doi:10.1074/jbc.275.16.12266 [Abstract] [Full Text] [PDF]

Shigeomi Shimizu, Toru Ide, Toshio Yanagida, and Yoshihide Tsujimoto: Electrophysiological Study of a Novel Large Pore Formed by Bax and the Voltage-dependent Anion Channel That Is Permeable to Cytochrome c
J. Biol. Chem. 2000 275: 12321-12325. First Published ; doi:10.1074/jbc.275.16.12321 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Anne Petiot, Eric Ogier-Denis, Edward F. C. Blommaart, Alfred J. Meijer, and Patrice Codogno: Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells.
J. Biol. Chem. 2000 275: 12360. [Full Text] [PDF]

Editorial:

Accelerated Publications:

DNA: Replication, Repair, and Recombination:

Genes: Structure and Regulation:

RNA: Structure, Metabolism, and Catalysis:

Protein Synthesis, Post-Translation Modification, and Degradation:

Protein Structure and Folding:

Enzyme Catalysis and Regulation:

Metabolism and Bioenergetics:

Glycobiology and Extracellular Matrices:

Lipids and Lipoproteins:

Membrane Transport, Structure, Function, and Biogenesis:

Molecular Basis Of Cell and Developmental Biology:

Mechanisms Of Signal Transduction:

Additions and Corrections: