Editorial:

HighWire Press Is 5 years old
J. Biol. Chem. 2000 275: 11539. [Full Text] [PDF]  

Accelerated Publications:

Kwang-Hwan Jhee, Peter McPhie, and Edith Wilson Miles

Yeast Cystathionine -Synthase Is a Pyridoxal Phosphate Enzyme but, Unlike the Human Enzyme, Is Not a Heme Protein
J. Biol. Chem. 2000 275: 11541-11544. [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Grigory L. Dianov, Tanja Thybo, Irina I. Dianova, Leonora J. Lipinski, and Vilhelm A. Bohr

Single Nucleotide Patch Base Excision Repair Is the Major Pathway for Removal of Thymine Glycol from DNA in Human Cell Extracts
J. Biol. Chem. 2000 275: 11809-11813. [Abstract] [Full Text] [PDF]  

Shinji Yasuhira and Akira Yasui

Alternative Excision Repair Pathway of UV-damaged DNA in Schizosaccharomyces pombe Operates Both in Nucleus and in Mitochondria
J. Biol. Chem. 2000 275: 11824-11828. [Abstract] [Full Text] [PDF]  

Marie-Hélène David-Cordonnier, Jacques Laval, and Peter O'Neill

Clustered DNA Damage, Influence on Damage Excision by XRS5 Nuclear Extracts and Escherichia coli Nth and Fpg Proteins
J. Biol. Chem. 2000 275: 11865-11873. [Abstract] [Full Text] [PDF]  

Deana A. Arnold and Stephen C. Kowalczykowski

Facilitated Loading of RecA Protein Is Essential to Recombination by RecBCD Enzyme
J. Biol. Chem. 2000 275: 12261-12265. [Abstract] [Full Text] [PDF]  

Kenichi Miyako, Chihiro Takamatsu, Shuyo Umeda, Tatsurou Tajiri, Masato Furuichi, Yusaku Nakabeppu, Mutsuo Sekiguchi, Naotaka Hamasaki, Koichiro Takeshige, and Dongchon Kang

Accumulation of Adenine DNA Glycosylase-sensitive Sites in Human Mitochondrial DNA
J. Biol. Chem. 2000 275: 12326-12330. [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Laurie A. Boyer, Xiao Shao, Richard H. Ebright, and Craig L. Peterson

Roles of the Histone H2A-H2B Dimers and the (H3-H4)₂ Tetramer in Nucleosome Remodeling by the SWI-SNF Complex
J. Biol. Chem. 2000 275: 11545-11552. [Abstract] [Full Text] [PDF]  

Thierry Douki, Magali Court, Sylvie Sauvaigo, Francette Odin, and Jean Cadet

Formation of the Main UV-induced Thymine Dimeric Lesions within Isolated and Cellular DNA as Measured by High Performance Liquid Chromatography-Tandem Mass Spectrometry
J. Biol. Chem. 2000 275: 11678-11685. [Abstract] [Full Text] [PDF]  

Xiaoyuan He, Thomas Hohn, and Johannes Fütterer

Transcriptional Activation of the Rice Tungro Bacilliform Virus Gene Is Critically Dependent on an Activator Element Located Immediately Upstream of the TATA Box
J. Biol. Chem. 2000 275: 11799-11808. [Abstract] [Full Text] [PDF]  

Jie Liu, Xuening Shen, Van-Anh Nguyen, George Kunos, and Bin Gao

₁ Adrenergic Agonist Induction of p21^waf1/cip1 mRNA Stability in Transfected HepG2 Cells Correlates with the Increased Binding of an AU-rich Element Binding Factor
J. Biol. Chem. 2000 275: 11846-11851. [Abstract] [Full Text] [PDF]  

Robert Harrod, Yu-Liang Kuo, Yong Tang, Yao Yao, Alex Vassilev, Yoshihiro Nakatani, and Chou-Zen Giam

p300 and p300/cAMP-responsive Element-binding Protein Associated Factor Interact with Human T-cell Lymphotropic Virus Type-1 Tax in a Multi-histone Acetyltransferase/Activator-Enhancer Complex
J. Biol. Chem. 2000 275: 11852-11857. [Abstract] [Full Text] [PDF]  

Laurent Beck and Daniel Markovich

The Mouse Na⁺-Sulfate Cotransporter Gene Nas1. CLONING, TISSUE DISTRIBUTION, GENE STRUCTURE, CHROMOSOMAL ASSIGNMENT, AND TRANSCRIPTIONAL REGULATION BY VITAMIN D
J. Biol. Chem. 2000 275: 11880-11890. [Abstract] [Full Text] [PDF]  

George M. Yousef, Albert Chang, and Eleftherios P. Diamandis

Identification and Characterization of KLK-L4, a New Kallikrein-like Gene That Appears to be Down-regulated in Breast Cancer Tissues
J. Biol. Chem. 2000 275: 11891-11898. [Abstract] [Full Text] [PDF]  

Katsuro Iwase, Kei Miyanaka, Atsuko Shimizu, Akitoshi Nagasaki, Tomomi Gotoh, Masataka Mori, and Masaki Takiguchi

Induction of Endothelial Nitric-oxide Synthase in Rat Brain Astrocytes by Systemic Lipopolysaccharide Treatment
J. Biol. Chem. 2000 275: 11929-11933. [Abstract] [Full Text] [PDF]  

Karin L. Meibom, Birgitte H. Kallipolitis, Richard H. Ebright, and Poul Valentin-Hansen

Identification of the Subunit of cAMP Receptor Protein (CRP) That Functionally Interacts with CytR in CRP-CytR-mediated Transcriptional Repression
J. Biol. Chem. 2000 275: 11951-11956. [Abstract] [Full Text] [PDF]  

Bridget C. Coughlin, Santuza M. R. Teixeira, Louis V. Kirchhoff, and John E. Donelson

Amastin mRNA Abundance in Trypanosoma cruzi Is Controlled by a 3'-Untranslated Region Position-dependent cis-Element and an Untranslated Region-binding Protein
J. Biol. Chem. 2000 275: 12051-12060. [Abstract] [Full Text] [PDF]  

Ryan S. Streeper, Christina A. Svitek, Joshua K. Goldman, and Richard M. O'Brien

Differential Role of Hepatocyte Nuclear Factor-1 in the Regulation of Glucose-6-phosphatase Catalytic Subunit Gene Transcription by cAMP in Liver- and Kidney-derived Cell Lines
J. Biol. Chem. 2000 275: 12108-12118. [Abstract] [Full Text] [PDF]  

Bart J. A. M. Jordi and Christopher F. Higgins

The Downstream Regulatory Element of the proU Operon of Salmonella typhimurium Inhibits Open Complex Formation by RNA Polymerase at a Distance
J. Biol. Chem. 2000 275: 12123-12128. [Abstract] [Full Text] [PDF]  

Chris A. Learn, Steven B. Mizel, and Charles E. McCall

mRNA and Protein Stability Regulate the Differential Expression of Pro- and Anti-inflammatory Genes in Endotoxin-tolerant THP-1 Cells
J. Biol. Chem. 2000 275: 12185-12193. [Abstract] [Full Text] [PDF]  

Abel Ferrández, José Luis García, and Eduardo Díaz

Transcriptional Regulation of the Divergent paa Catabolic Operons for Phenylacetic Acid Degradation in Escherichia coli
J. Biol. Chem. 2000 275: 12214-12222. [Abstract] [Full Text] [PDF]  

Yu Liu, Xiaohong Zhong, Wenhui Li, Michael G. Brattain, and Sunandita S. Banerji

The Role of Sp1 in the Differential Expression of Transforming Growth Factor- Receptor Type II in Human Breast Adenocarcinoma MCF-7 Cells
J. Biol. Chem. 2000 275: 12231-12236. [Abstract] [Full Text] [PDF]  

Erik Schoenmakers, Guy Verrijdt, Ben Peeters, Guido Verhoeven, Wilfried Rombauts, and Frank Claessens

Differences in DNA Binding Characteristics of the Androgen and Glucocorticoid Receptors Can Determine Hormone-specific Responses
J. Biol. Chem. 2000 275: 12290-12297. [Abstract] [Full Text] [PDF]  

Guy Verrijdt, Erik Schoenmakers, Annemie Haelens, Ben Peeters, Guido Verhoeven, Wilfried Rombauts, and Frank Claessens

Change of Specificity Mutations in Androgen-selective Enhancers. EVIDENCE FOR A ROLE OF DIFFERENTIAL DNA BINDING BY THE ANDROGEN RECEPTOR
J. Biol. Chem. 2000 275: 12298-12305. [Abstract] [Full Text] [PDF]  

Chien-Fu Huang, Yeau-Ching Wang, Der-An Tsao, Shiu-Feng Tung, Young-Sun Lin, and Cheng-Wen Wu

Antagonism between Members of the CNC-bZIP Family and the Immediate-Early Protein IE2 of Human Cytomegalovirus
J. Biol. Chem. 2000 275: 12313-12320. [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Peter Askjaer, Rita Rosendahl, and Jørgen Kjems

Nuclear Export of the DEAD Box An3 Protein by CRM1 Is Coupled to An3 Helicase Activity
J. Biol. Chem. 2000 275: 11561-11568. [Abstract] [Full Text] [PDF]  

Alessio Peracchi

Preferential Activation of the 8-17 Deoxyribozyme by Ca²⁺ Ions. EVIDENCE FOR THE IDENTITY OF 8-17 WITH THE CATALYTIC DOMAIN OF THE MG5 DEOXYRIBOZYME
J. Biol. Chem. 2000 275: 11693-11697. [Abstract] [Full Text] [PDF]  

Dan A. Dixon, Craig D. Kaplan, Thomas M. McIntyre, Guy A. Zimmerman, and Stephen M. Prescott

Post-transcriptional Control of Cyclooxygenase-2 Gene Expression. THE ROLE OF THE 3'-UNTRANSLATED REGION
J. Biol. Chem. 2000 275: 11750-11757. [Abstract] [Full Text] [PDF]  

Jean-Marc Lanchy, Catherine Isel, Gérard Keith, Stuart F. J. Le Grice, Chantal Ehresmann, Bernard Ehresmann, and Roland Marquet

Dynamics of the HIV-1 Reverse Transcription Complex during Initiation of DNA Synthesis
J. Biol. Chem. 2000 275: 12306-12312. [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Jinhua Feng, David L. Smith, and Jean B. Smith

Human Lens -Crystallin Solubility
J. Biol. Chem. 2000 275: 11585-11590. [Abstract] [Full Text] [PDF]  

Julie Soutourina, Sylvain Blanquet, and Pierre Plateau

D-Tyrosyl-tRNA^Tyr Metabolism in Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 11626-11630. [Abstract] [Full Text] [PDF]  

Theophile Ohlmann, Marcelo Lopez-Lastra, and Jean-Luc Darlix

An Internal Ribosome Entry Segment Promotes Translation of the Simian Immunodeficiency Virus Genomic RNA
J. Biol. Chem. 2000 275: 11899-11906. [Abstract] [Full Text] [PDF]  

Doris Germain, Adrian Russell, Anne Thompson, and Joy Hendley

Ubiquitination of Free Cyclin D1 Is Independent of Phosphorylation on Threonine 286
J. Biol. Chem. 2000 275: 12074-12079. [Abstract] [Full Text] [PDF]  

Takanori Muto, Michael D. Feese, Yoshihiro Shimada, Youko Kudou, Tomoyuki Okamoto, Tadashi Ozawa, Tomoyuki Tahara, Hideya Ohashi, Kinya Ogami, Takashi Kato, Hiroshi Miyazaki, and Ryota Kuroki

Functional Analysis of the C-terminal Region of Recombinant Human Thrombopoietin. C-TERMINAL REGION OF THROMBOPOIETIN IS A "SHUTTLE" PEPTIDE TO HELP SECRETION
J. Biol. Chem. 2000 275: 12090-12094. [Abstract] [Full Text] [PDF]  

Joanne F. Berson, David W. Frank, Paul A. Calvo, Bert M. Bieler, and Michael S. Marks

A Common Temperature-sensitive Allelic Form of Human Tyrosinase Is Retained in the Endoplasmic Reticulum at the Nonpermissive Temperature
J. Biol. Chem. 2000 275: 12281-12289. [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Marco G. Casarotto, Frank Gibson, Suzi M. Pace, Suzanne M. Curtis, Mark Mulcair, and Angela F. Dulhunty

A Structural Requirement for Activation of Skeletal Ryanodine Receptors by Peptides of the Dihydropyridine Receptor II-III Loop
J. Biol. Chem. 2000 275: 11631-11637. [Abstract] [Full Text] [PDF]  

Sabine Frank, Ariel Lustig, Therese Schulthess, Jürgen Engel, and Richard A. Kammerer

A Distinct Seven-residue Trigger Sequence Is Indispensable for Proper Coiled-coil Formation of the Human Macrophage Scavenger Receptor Oligomerization Domain
J. Biol. Chem. 2000 275: 11672-11677. [Abstract] [Full Text] [PDF]  

David J. J. Waugh, Ming-Ming Zhao, Michael J. Zuscik, and Dianne M. Perez

Novel Aromatic Residues in Transmembrane Domains IV and V Involved in Agonist Binding at _1a-Adrenergic Receptors
J. Biol. Chem. 2000 275: 11698-11705. [Abstract] [Full Text] [PDF]  

Germán Rivas, Asunción López, Jesús Mingorance, María José Ferrándiz, Silvia Zorrilla, Allen P. Minton, Miguel Vicente, and José Manuel Andreu

Magnesium-induced Linear Self-association of the FtsZ Bacterial Cell Division Protein Monomer. THE PRIMARY STEPS FOR FtsZ ASSEMBLY
J. Biol. Chem. 2000 275: 11740-11749. [Abstract] [Full Text] [PDF]  

Vinod Singh and Wolfgang E. Merz

Disulfide Bond Formation Is Not Required for Human Chorionic Gonadotropin Subunit Association. STUDIES WITH DITHIOTHREITOL IN JEG-3 CELLS
J. Biol. Chem. 2000 275: 11765-11770. [Abstract] [Full Text] [PDF]  

Sergey N. Fedosov, Natalya U. Fedosova, Ebba Nexø, and Torben E. Petersen

Conformational Changes of Transcobalamin Induced by Aquocobalamin Binding. MECHANISM OF SUBSTITUTION OF THE COBALT-COORDINATED GROUP IN THE BOUND LIGAND
J. Biol. Chem. 2000 275: 11791-11798. [Abstract] [Full Text] [PDF]  

Ramona Dickson, Celeste Weiss, Richard J. Howard, Sharon P. Alldrick, R. John Ellis, George Lorimer, Abdussalam Azem, and Paul V. Viitanen

Reconstitution of Higher Plant Chloroplast Chaperonin 60 Tetradecamers Active in Protein Folding
J. Biol. Chem. 2000 275: 11829-11835. [Abstract] [Full Text] [PDF]  

Klara Ösapay, Dat Tran, Alexey S. Ladokhin, Stephen H. White, Agnes H. Henschen, and Michael E. Selsted

Formation and Characterization of a Single Trp-Trp Cross-link in Indolicidin That Confers Protease Stability without Altering Antimicrobial Activity
J. Biol. Chem. 2000 275: 12017-12022. [Abstract] [Full Text] [PDF]  

Yael Kenan, Taku Murata, Yasmin Shakur, Eva Degerman, and Vincent C. Manganiello

Functions of the N-terminal Region of Cyclic Nucleotide Phosphodiesterase 3 (PDE 3) Isoforms
J. Biol. Chem. 2000 275: 12331-12338. [Abstract] [Full Text] [PDF]  

Dieter P. Reinhardt, Robert N. Ono, Holger Notbohm, Peter K. Müller, Hans Peter Bächinger, and Lynn Y. Sakai

Mutations in Calcium-binding Epidermal Growth Factor Modules Render Fibrillin-1 Susceptible to Proteolysis. A POTENTIAL DISEASE-CAUSING MECHANISM IN MARFAN SYNDROME
J. Biol. Chem. 2000 275: 12339-12345. [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Henry A. Charlier, Jr. and Bryce V. Plapp

Kinetic Cooperativity of Human Liver Alcohol Dehydrogenase ₂
J. Biol. Chem. 2000 275: 11569-11575. [Abstract] [Full Text] [PDF]  

Véronique Marcel, Sandino Estrada-Mondaca, Frédéric Magné, Jure Stojan, Alain Klaébé, and Didier Fournier

Exploration of the Drosophila Acetylcholinesterase Substrate Activation Site Using a Reversible Inhibitor (Triton X-100) and Mutated Enzymes
J. Biol. Chem. 2000 275: 11603-11609. [Abstract] [Full Text] [PDF]  

Christine J. van Dalen, Christine C. Winterbourn, Revathy Senthilmohan, and Anthony J. Kettle

Nitrite as a Substrate and Inhibitor of Myeloperoxidase. IMPLICATIONS FOR NITRATION AND HYPOCHLOROUS ACID PRODUCTION AT SITES OF INFLAMMATION
J. Biol. Chem. 2000 275: 11638-11644. [Abstract] [Full Text] [PDF]  

Rokus Renirie, Wieger Hemrika, and Ron Wever

Peroxidase and Phosphatase Activity of Active-site Mutants of Vanadium Chloroperoxidase from the Fungus Curvularia inaequalis. IMPLICATIONS FOR THE CATALYTIC MECHANISMS
J. Biol. Chem. 2000 275: 11650-11657. [Abstract] [Full Text] [PDF]  

Angela Wilks and Pierre Moënne-Loccoz

Identification of the Proximal Ligand His-20 in Heme Oxygenase (Hmu O) from Corynebacterium diphtheriae. OXIDATIVE CLEAVAGE OF THE HEME MACROCYCLE DOES NOT REQUIRE THE PROXIMAL HISTIDINE
J. Biol. Chem. 2000 275: 11686-11692. [Abstract] [Full Text] [PDF]  

Luis M. Quirós, Rodrigo J. Carbajo, Alfredo F. Braña, and José A. Salas

Glycosylation of Macrolide Antibiotics. PURIFICATION AND KINETIC STUDIES OF A MACROLIDE GLYCOSYLTRANSFERASE FROM STREPTOMYCES ANTIBIOTICUS
J. Biol. Chem. 2000 275: 11713-11720. [Abstract] [Full Text] [PDF]  

John P. Plastaras, F. Peter Guengerich, Daniel W. Nebert, and Lawrence J. Marnett

Xenobiotic-metabolizing Cytochromes P450 Convert Prostaglandin Endoperoxide to Hydroxyheptadecatrienoic Acid and the Mutagen, Malondialdehyde
J. Biol. Chem. 2000 275: 11784-11790. [Abstract] [Full Text] [PDF]  

Johannes von Lintig and Klaus Vogt

Filling the Gap in Vitamin A Research. MOLECULAR IDENTIFICATION OF AN ENZYME CLEAVING -CAROTENE TO RETINAL
J. Biol. Chem. 2000 275: 11915-11920. [Abstract] [Full Text] [PDF]  

Tristan J. Fiedler, Curt A. Davey, and Roger E. Fenna

X-ray Crystal Structure and Characterization of Halide-binding Sites of Human Myeloperoxidase at 1.8 Å Resolution
J. Biol. Chem. 2000 275: 11964-11971. [Abstract] [Full Text] [PDF]  

Sonia Hernandez-Barrantes, Marta Toth, M. Margarida Bernardo, Maria Yurkova, David C. Gervasi, Yuval Raz, QingXiang Amy Sang, and Rafael Fridman

Binding of Active (57 kDa) Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) to Tissue Inhibitor of Metalloproteinase (TIMP)-2 Regulates MT1-MMP Processing and Pro-MMP-2 Activation
J. Biol. Chem. 2000 275: 12080-12089. [Abstract] [Full Text] [PDF]  

Françoise Paturiaux-Hanocq, Jacqueline Hanocq-Quertier, Maria Lucia Cardoso de Almeida, Derek P. Nolan, Annette Pays, Luc Vanhamme, Jan Van den Abbeele, Christine L. Wasunna, Mark Carrington, and Etienne Pays

A Role for the Dynamic Acylation of a Cluster of Cysteine Residues in Regulating the Activity of the Glycosylphosphatidylinositol-specific Phospholipase C of Trypanosoma brucei
J. Biol. Chem. 2000 275: 12147-12155. [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Jeane M. De Freitas, Amir Liba, Rogerio Meneghini, Joan Selverstone Valentine, and Edith Butler Gralla

Yeast Lacking Cu-Zn Superoxide Dismutase Show Altered Iron Homeostasis. ROLE OF OXIDATIVE STRESS IN IRON METABOLISM
J. Biol. Chem. 2000 275: 11645-11649. [Abstract] [Full Text] [PDF]  

Graciela B. Sala-Newby, Nicola V. E. Freeman, Andrzej C. Skladanowski, and Andrew C. Newby

Distinct Roles for Recombinant Cytosolic 5'-Nucleotidase-I and -II in AMP and IMP Catabolism in COS-7 and H9c2 Rat Myoblast Cell Lines
J. Biol. Chem. 2000 275: 11666-11671. [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Simi Ali, Adrian C. V. Palmer, Ben Banerjee, Sarah J. Fritchley, and John A. Kirby

Examination of the Function of RANTES, MIP-1, and MIP-1 following Interaction with Heparin-like Glycosaminoglycans
J. Biol. Chem. 2000 275: 11721-11727. [Abstract] [Full Text] [PDF]  

Shih-Houng Young, Wen-Ji Dong, and Robert R. Jacobs

Observation of a Partially Opened Triple-helix Conformation in 13--Glucan by Fluorescence Resonance Energy Transfer Spectroscopy
J. Biol. Chem. 2000 275: 11874-11879. [Abstract] [Full Text] [PDF]  

Marcus Mreyen, Alan Champion, Supriya Srinivasan, Peter Karuso, Keith L. Williams, and Nicolle H. Packer

Multiple O-Glycoforms on the Spore Coat Protein SP96 in Dictyostelium discoideum. Fuc(1-3)GlcNAc--1-P-Ser IS THE MAJOR MODIFICATION
J. Biol. Chem. 2000 275: 12164-12174. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Samar M. Hammad, Jeremy L. Barth, Christian Knaak, and W. Scott Argraves

Megalin Acts in Concert with Cubilin to Mediate Endocytosis of High Density Lipoproteins
J. Biol. Chem. 2000 275: 12003-12008. [Abstract] [Full Text] [PDF]  

Mary G. Sorci-Thomas, Mike Thomas, Linda Curtiss, and Mark Landrum

Single Repeat Deletion in ApoA-I Blocks Cholesterol Esterification and Results in Rapid Catabolism of 6 and Wild-type ApoA-I in Transgenic Mice
J. Biol. Chem. 2000 275: 12156-12163. [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Nicola R. Stanley, Tracy Palmer, and Ben C. Berks

The Twin Arginine Consensus Motif of Tat Signal Peptides Is Involved in Sec-independent Protein Targeting in Escherichia coli
J. Biol. Chem. 2000 275: 11591-11596. [Abstract] [Full Text] [PDF]  

Danqing Li, Koichi Takimoto, and Edwin S. Levitan

Surface Expression of Kv1 Channels Is Governed by a C-terminal Motif
J. Biol. Chem. 2000 275: 11597-11602. [Abstract] [Full Text] [PDF]  

Takeshi Yamamoto, Roque El-Hayek, and Noriaki Ikemoto

Postulated Role of Interdomain Interaction within the Ryanodine Receptor in Ca²⁺ Channel Regulation
J. Biol. Chem. 2000 275: 11618-11625. [Abstract] [Full Text] [PDF]  

Alessandro Prinetti, Vanna Chigorno, Guido Tettamanti, and Sandro Sonnino

Sphingolipid-enriched Membrane Domains from Rat Cerebellar Granule Cells Differentiated in Culture. A COMPOSITIONAL STUDY
J. Biol. Chem. 2000 275: 11658-11665. [Abstract] [Full Text] [PDF]  

Thomas Steinkamp, Kerstin Hill, Silke C. Hinnah, Richard Wagner, Thomas Röhl, Kai Pohlmeyer, and Jürgen Soll

Identification of the Pore-forming Region of the Outer Chloroplast Envelope Protein OEP16
J. Biol. Chem. 2000 275: 11758-11764. [Abstract] [Full Text] [PDF]  

Patrick R. D'Silva and Anil K. Lala

Organization of Diphtheria Toxin in Membranes. A HYDROPHOBIC PHOTOLABELING STUDY
J. Biol. Chem. 2000 275: 11771-11777. [Abstract] [Full Text] [PDF]  

Guo Guang Du, Vijay K. Khanna, and David H. MacLennan

Mutation of Divergent Region 1 Alters Caffeine and Ca²⁺ Sensitivity of the Skeletal Muscle Ca²⁺ Release Channel (Ryanodine Receptor)
J. Biol. Chem. 2000 275: 11778-11783. [Abstract] [Full Text] [PDF]  

Andrew S. Opat, Fiona Houghton, and Paul A. Gleeson

Medial Golgi but Not Late Golgi Glycosyltransferases Exist as High Molecular Weight Complexes. ROLE OF LUMINAL DOMAIN IN COMPLEX FORMATION AND LOCALIZATION
J. Biol. Chem. 2000 275: 11836-11845. [Abstract] [Full Text] [PDF]  

Haiyan Tong, Weina Chen, Robert E. London, Elizabeth Murphy, and Charles Steenbergen

Preconditioning Enhanced Glucose Uptake Is Mediated by p38 MAP Kinase Not by Phosphatidylinositol 3-Kinase
J. Biol. Chem. 2000 275: 11981-11986. [Abstract] [Full Text] [PDF]  

Ronald S. Kaplan, June A. Mayor, David Brauer, Rusudan Kotaria, D. Eric Walters, and Antony M. Dean

The Yeast Mitochondrial Citrate Transport Protein. PROBING THE SECONDARY STRUCTURE OF TRANSMEMBRANE DOMAIN IV AND IDENTIFICATION OF RESIDUES THAT LIKELY COMPRISE A PORTION OF THE CITRATE TRANSLOCATION PATHWAY
J. Biol. Chem. 2000 275: 12009-12016. [Abstract] [Full Text] [PDF]  

Anirban Siddhanta, Jonathan M. Backer, and Dennis Shields

Inhibition of Phosphatidic Acid Synthesis Alters the Structure of the Golgi Apparatus and Inhibits Secretion in Endocrine Cells
J. Biol. Chem. 2000 275: 12023-12031. [Abstract] [Full Text] [PDF]  

Jianying Liu, Xugang Qiao, Dongyi Du, and Mary Gwo-Shu Lee

Receptor-mediated Endocytosis in the Procyclic Form of Trypanosoma brucei
J. Biol. Chem. 2000 275: 12032-12040. [Abstract] [Full Text] [PDF]  

Angela G. Brittsan, Andrew N. Carr, Albrecht G. Schmidt, and Evangelia G. Kranias

Maximal Inhibition of SERCA2 Ca²⁺ Affinity by Phospholamban in Transgenic Hearts Overexpressing a Non-phosphorylatable Form of Phospholamban
J. Biol. Chem. 2000 275: 12129-12135. [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Masanori Yoshizumi, Jun-ichi Abe, Judith Haendeler, Qunhua Huang, and Bradford C. Berk

Src and Cas Mediate JNK Activation but Not ERK1/2 and p38 Kinases by Reactive Oxygen Species
J. Biol. Chem. 2000 275: 11706-11712. [Abstract] [Full Text] [PDF]  

Koji Tokoyoda, Yoshihiro Takemoto, Toshinori Nakayama, Takao Arai, and Masato Kubo

Synergism between the Calmodulin-binding and Autoinhibitory Domains on Calcineurin Is Essential for the Induction of Their Phosphatase Activity
J. Biol. Chem. 2000 275: 11728-11734. [Abstract] [Full Text] [PDF]  

Rennolds S. Ostrom, Caroline Gregorian, and Paul A. Insel

Cellular Release of and Response to ATP as Key Determinants of the Set-Point of Signal Transduction Pathways
J. Biol. Chem. 2000 275: 11735-11739. [Abstract] [Full Text] [PDF]  

Etsuro Hatano, Cynthia A. Bradham, Alexander Stark, Yuji Iimuro, John J. Lemasters, and David A. Brenner

The Mitochondrial Permeability Transition Augments Fas-induced Apoptosis in Mouse Hepatocytes
J. Biol. Chem. 2000 275: 11814-11823. [Abstract] [Full Text] [PDF]  

Li-Na Wei, Xinli Hu, and Chatchai Chinpaisal

Constitutive Activation of Retinoic Acid Receptor 2 Promoter by Orphan Nuclear Receptor TR2
J. Biol. Chem. 2000 275: 11907-11914. [Abstract] [Full Text] [PDF]  

Shi-Fang Yan, Jiesheng Lu, Yu Shan Zou, Walter Kisiel, Nigel Mackman, Michael Leitges, Susan Steinberg, David Pinsky, and David Stern

Protein Kinase C- and Oxygen Deprivation. A NOVEL Egr-1-DEPENDENT PATHWAY FOR FIBRIN DEPOSITION IN HYPOXEMIC VASCULATURE
J. Biol. Chem. 2000 275: 11921-11928. [Abstract] [Full Text] [PDF]  

Jan Domin, Ibragim Gaidarov, Mary E. K. Smith, James H. Keen, and Michael D. Waterfield

The Class II Phosphoinositide 3-Kinase PI3K-C2 Is Concentrated in the Trans-Golgi Network and Present in Clathrin-coated Vesicles
J. Biol. Chem. 2000 275: 11943-11950. [Abstract] [Full Text] [PDF]  

Olav Klingenberg, Antoni Wiedlocha, Lucía Citores, and Sjur Olsnes

Requirement of Phosphatidylinositol 3-Kinase Activity for Translocation of Exogenous aFGF to the Cytosol and Nucleus
J. Biol. Chem. 2000 275: 11972-11980. [Abstract] [Full Text] [PDF]  

Meenakshi A. Chellaiah, Norihito Soga, Suzanne Swanson, Sandy McAllister, Ulises Alvarez, Dongmei Wang, Steven F. Dowdy, and Keith A. Hruska

Rho-A Is Critical for Osteoclast Podosome Organization, Motility, and Bone Resorption
J. Biol. Chem. 2000 275: 11993-12002. [Abstract] [Full Text] [PDF]  

Cristina Murga, Shigetomo Fukuhara, and J. Silvio Gutkind

A Novel Role for Phosphatidylinositol 3-Kinase  in Signaling from G Protein-coupled Receptors to Akt
J. Biol. Chem. 2000 275: 12069-12073. [Abstract] [Full Text] [PDF]  

Juan M. Zapata, Shu-ichi Matsuzawa, Adam Godzik, Eugen Leo, Steven A. Wasserman, and John C. Reed

The Drosophila Tumor Necrosis Factor Receptor-associated Factor-1 (DTRAF1) Interacts with Pelle and Regulates NFB Activity
J. Biol. Chem. 2000 275: 12102-12107. [Abstract] [Full Text] [PDF]  

Qiming J. Wang, Tzan-Wei Fang, David Fenick, Susan Garfield, Bruno Bienfait, Victor E. Marquez, and Peter M. Blumberg

The Lipophilicity of Phorbol Esters as a Critical Factor in Determining the Pattern of Translocation of Protein Kinase C  Fused to Green Fluorescent Protein
J. Biol. Chem. 2000 275: 12136-12146. [Abstract] [Full Text] [PDF]  

Mingya Liu, Lisan L. Parker, Brian E. Wadzinski, and Bih-Hwa Shieh

Reversible Phosphorylation of the Signal Transduction Complex in Drosophila Photoreceptors
J. Biol. Chem. 2000 275: 12194-12199. [Abstract] [Full Text] [PDF]  

Madalina Stanciu, Ying Wang, Ruth Kentor, Nancy Burke, Simon Watkins, Geraldine Kress, Ian Reynolds, Eric Klann, Maria R. Angiolieri, Jon W. Johnson, and Donald B. DeFranco

Persistent Activation of ERK Contributes to Glutamate-induced Oxidative Toxicity in a Neuronal Cell Line and Primary Cortical Neuron Cultures
J. Biol. Chem. 2000 275: 12200-12206. [Abstract] [Full Text] [PDF]  

Ulrich Böcker, Arndt Schottelius, Joanna M. Watson, Lisa Holt, Laura L. Licato, David A. Brenner, R. Balfour Sartor, and Christian Jobin

Cellular Differentiation Causes a Selective Down-regulation of Interleukin (IL)-1-mediated NF-B Activation and IL-8 Gene Expression in Intestinal Epithelial Cells
J. Biol. Chem. 2000 275: 12207-12213. [Abstract] [Full Text] [PDF]  

Deming Wang, Xin Yu, Richard A. Cohen, and Peter Brecher

Distinct Effects of N-Acetylcysteine and Nitric Oxide on Angiotensin II-induced Epidermal Growth Factor Receptor Phosphorylation and Intracellular Ca²⁺ Levels
J. Biol. Chem. 2000 275: 12223-12230. [Abstract] [Full Text] [PDF]  

Karim Bordji, Joël-Paul Grillasca, Jean-Noël Gouze, Jacques Magdalou, Hervé Schohn, Jean-Marie Keller, Arnaud Bianchi, Michel Dauça, Patrick Netter, and Bernard Terlain

Evidence for the Presence of Peroxisome Proliferator-activated Receptor (PPAR)  and  and Retinoid Z Receptor in Cartilage. PPAR ACTIVATION MODULATES THE EFFECTS OF INTERLEUKIN-1 ON RAT CHONDROCYTES
J. Biol. Chem. 2000 275: 12243-12250. [Abstract] [Full Text] [PDF]  

Robert Grosse, Susanne Roelle, Andreas Herrlich, Julia Höhn, and Thomas Gudermann

Epidermal Growth Factor Receptor Tyrosine Kinase Mediates Ras Activation by Gonadotropin-releasing Hormone
J. Biol. Chem. 2000 275: 12251-12260. [Abstract] [Full Text] [PDF]  

Shuang Huang, Liguo New, Zhixing Pan, Jiahuai Han, and Glen R. Nemerow

Urokinase Plasminogen Activator/Urokinase-specific Surface Receptor Expression and Matrix Invasion by Breast Cancer Cells Requires Constitutive p38 Mitogen-activated Protein Kinase Activity
J. Biol. Chem. 2000 275: 12266-12272. [Abstract] [Full Text] [PDF]  

Shigeomi Shimizu, Toru Ide, Toshio Yanagida, and Yoshihide Tsujimoto

Electrophysiological Study of a Novel Large Pore Formed by Bax and the Voltage-dependent Anion Channel That Is Permeable to Cytochrome c
J. Biol. Chem. 2000 275: 12321-12325. [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Andrew Giovanni, Elizabeth Keramaris, Erick J. Morris, Sheng T. Hou, Michael O'Hare, Nick Dyson, George S. Robertson, Ruth S. Slack, and David S. Park

E2F1 Mediates Death of B-amyloid-treated Cortical Neurons in a Manner Independent of p53 and Dependent on Bax and Caspase 3
J. Biol. Chem. 2000 275: 11553-11560. [Abstract] [Full Text] [PDF]  

Dora Bigler, Yuji Takahashi, Michellee S. Chen, Eduardo A. C. Almeida, Laurie Osbourne, and Judith M. White

Sequence-specific Interaction between the Disintegrin Domain of Mouse ADAM 2 (Fertilin ) and Murine Eggs. ROLE OF THE ₆ INTEGRIN SUBUNIT
J. Biol. Chem. 2000 275: 11576-11584. [Abstract] [Full Text] [PDF]  

Kate A. Powell, Valentina A. Valova, Chandra S. Malladi, Ole N. Jensen, Martin R. Larsen, and Phillip J. Robinson

Phosphorylation of Dynamin I on Ser-795 by Protein Kinase C Blocks Its Association with Phospholipids
J. Biol. Chem. 2000 275: 11610-11617. [Abstract] [Full Text] [PDF]  

Jay W. Tichelaar, Wei Lu, and Jeffrey A. Whitsett

Conditional Expression of Fibroblast Growth Factor-7 in the Developing and Mature Lung
J. Biol. Chem. 2000 275: 11858-11864. [Abstract] [Full Text] [PDF]  

Timothy P. Lockwich, Xibao Liu, Brij B. Singh, Julie Jadlowiec, Sharon Weiland, and Indu S. Ambudkar

Assembly of Trp1 in a Signaling Complex Associated with Caveolin-Scaffolding Lipid Raft Domains
J. Biol. Chem. 2000 275: 11934-11942. [Abstract] [Full Text] [PDF]  

Kiyoshi Ariizumi, Guo-Liang Shen, Sojin Shikano, Robert Ritter, III, Paul Zukas, Dale Edelbaum, Akimichi Morita, and Akira Takashima

Cloning of a Second Dendritic Cell-associated C-type Lectin (Dectin-2) and Its Alternatively Spliced Isoforms
J. Biol. Chem. 2000 275: 11957-11963. [Abstract] [Full Text] [PDF]  

Yoshifumi Banzai, Hiroaki Miki, Hideki Yamaguchi, and Tadaomi Takenawa

Essential Role of Neural Wiskott-Aldrich Syndrome Protein in Neurite Extension in PC12 Cells and Rat Hippocampal Primary Culture Cells
J. Biol. Chem. 2000 275: 11987-11992. [Abstract] [Full Text] [PDF]  

Liana Adam, Ratna Vadlamudi, Mahitosh Mandal, Jonathan Chernoff, and Rakesh Kumar

Regulation of Microfilament Reorganization and Invasiveness of Breast Cancer Cells by Kinase Dead p21-activated Kinase-1
J. Biol. Chem. 2000 275: 12041-12050. [Abstract] [Full Text] [PDF]  

Olaf Rosorius, Barbara Fries, Roland H. Stauber, Nicole Hirschmann, Dorian Bevec, and Joachim Hauber

Human Ribosomal Protein L5 Contains Defined Nuclear Localization and Export Signals
J. Biol. Chem. 2000 275: 12061-12068. [Abstract] [Full Text] [PDF]  

Ann McGinty, Yu-Wen E. Chang, Andrey Sorokin, Dirk Bokemeyer, and Michael J. Dunn

Cyclooxygenase-2 Expression Inhibits Trophic Withdrawal Apoptosis in Nerve Growth Factor-differentiated PC12 Cells
J. Biol. Chem. 2000 275: 12095-12101. [Abstract] [Full Text] [PDF]  

Morichika Konishi, Tadahisa Mikami, Masahiro Yamasaki, Ayumi Miyake, and Nobuyuki Itoh

Fibroblast Growth Factor-16 Is a Growth Factor for Embryonic Brown Adipocytes
J. Biol. Chem. 2000 275: 12119-12122. [Abstract] [Full Text] [PDF]  

Lihua He, Ann T. Poblenz, Carlos J. Medrano, and Donald A. Fox

Lead and Calcium Produce Rod Photoreceptor Cell Apoptosis by Opening the Mitochondrial Permeability Transition Pore
J. Biol. Chem. 2000 275: 12175-12184. [Abstract] [Full Text] [PDF]  

Boning Gao, Yoshitaka Sekido, Anton Maximov, Mohamad Saad, Eva Forgacs, Farida Latif, Ming H. Wei, Michael Lerman, Jung-Ha Lee, Edward Perez-Reyes, Ilya Bezprozvanny, and John D. Minna

Functional Properties of a New Voltage-dependent Calcium Channel ₂ Auxiliary Subunit Gene (CACNA2D2)
J. Biol. Chem. 2000 275: 12237-12242. [Abstract] [Full Text] [PDF]  

Yan Larry Zhou and Malcolm L. Snead

Identification of CCAAT/Enhancer-binding Protein  as a Transactivator of the Mouse Amelogenin Gene
J. Biol. Chem. 2000 275: 12273-12280. [Abstract] [Full Text] [PDF]  

Mary A. Dionne, Angela Sanchez, and Duane A. Compton

ch-TOGp Is Required for Microtubule Aster Formation in a Mammalian Mitotic Extract
J. Biol. Chem. 2000 275: 12346-12352. [Abstract] [Full Text] [PDF]  

Young-Mee Yoon, Chun-Do Oh, Do-Yoon Kim, Young-Sup Lee, Jeen-Woo Park, Tae-Lin Huh, Shin-Sung Kang, and Jang-Soo Chun

Epidermal Growth Factor Negatively Regulates Chondrogenesis of Mesenchymal Cells by Modulating the Protein Kinase C-, Erk-1, and p38 MAPK Signaling Pathways
J. Biol. Chem. 2000 275: 12353-12359. [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Anne Petiot, Eric Ogier-Denis, Edward F. C. Blommaart, Alfred J. Meijer, and Patrice Codogno

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells.
J. Biol. Chem. 2000 275: 12360. [Full Text] [PDF]  

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