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Table of Contents: May 19 2000; 275 (20)   [Index by Author]       Other Issues:  
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Accelerated Publications:

Yijun Zhu, Chao Qi, Yuzhi Jia, Jeffrey S. Nye, M. Sambasiva Rao, and Janardan K. Reddy
Deletion of PBP/PPARBP, the Gene for Nuclear Receptor Coactivator Peroxisome Proliferator-activated Receptor-binding Protein, Results in Embryonic Lethality
J. Biol. Chem. 2000 275: 14779-14782. [Abstract] [Full Text] [PDF]  

Alla Danilkovitch-Miagkova, Debora Angeloni, Alison Skeel, Shannon Donley, Michael Lerman, and Edward J. Leonard
Integrin-mediated RON Growth Factor Receptor Phosphorylation Requires Tyrosine Kinase Activity of Both the Receptor and c-Src
J. Biol. Chem. 2000 275: 14783-14786. [Abstract] [Full Text] [PDF]  

Gary LeRoy, Alejandra Loyola, William S. Lane, and Danny Reinberg
Purification and Characterization of a Human Factor That Assembles and Remodels Chromatin
J. Biol. Chem. 2000 275: 14787-14790. [Abstract] [Full Text] [PDF]  

Noriyuki Yanaka, Kinji Kobayashi, Koji Wakimoto, Eriko Yamada, Hiroshi Imahie, Yuji Imai, and Chisato Mori
Insertional Mutation of the Murine Kisimo Locus Caused a Defect in Spermatogenesis
J. Biol. Chem. 2000 275: 14791-14794. [Abstract] [Full Text] [PDF]  

Kristian Kvint, Anne Farewell, and Thomas Nyström
RpoS-dependent Promoters Require Guanosine Tetraphosphate for Induction Even in the Presence of High Levels of sigma s
J. Biol. Chem. 2000 275: 14795-14798. [Abstract] [Full Text] [PDF]  


DNA: Replication Repair and Recombination:

Gary J. Latham, Eva Forgacs, William A. Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A. Kunkel, Samuel H. Wilson, and R. Stephen Lloyd
Vertical-scanning Mutagenesis of a Critical Tryptophan in the "Minor Groove Binding Track" of HIV-1 Reverse Transcriptase. MAJOR GROOVE DNA ADDUCTS IDENTIFY SPECIFIC PROTEIN INTERACTIONS IN THE MINOR GROOVE
J. Biol. Chem. 2000 275: 15025-15033. [Abstract] [Full Text] [PDF]  

David F. Shechter, Carol Y. Ying, and Jean Gautier
The Intrinsic DNA Helicase Activity of Methanobacterium thermoautotrophicum Delta H Minichromosome Maintenance Protein
J. Biol. Chem. 2000 275: 15049-15059. [Abstract] [Full Text] [PDF]  

Frédéric R. Sallmann, Momchil D. Vodenicharov, Zhao-Qi Wang, and Guy G. Poirier
Characterization of sPARP-1. AN ALTERNATIVE PRODUCT OF PARP-1 GENE WITH POLY(ADP-RIBOSE) POLYMERASE ACTIVITY INDEPENDENT OF DNA STRAND BREAKS
J. Biol. Chem. 2000 275: 15504-15511. [Abstract] [Full Text] [PDF]  

H. Garry Dallmann, Sungsub Kim, Arthur E. Pritchard, Kenneth J. Marians, and Charles S. McHenry
Characterization of the Unique C Terminus of the Escherichia coli tau  DnaX Protein. MONOMERIC C-tau BINDS alpha  AND DnaB AND CAN PARTIALLY REPLACE tau  IN RECONSTITUTED REPLICATION FORKS
J. Biol. Chem. 2000 275: 15512-15519. [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Alan L. Lehman and Michael E. Dahmus
The Sensitivity of RNA Polymerase II in Elongation Complexes to C-terminal Domain Phosphatase
J. Biol. Chem. 2000 275: 14923-14932. [Abstract] [Full Text] [PDF]  

Ying Han and Thomas Kodadek
Peptides Selected to Bind the Gal80 Repressor Are Potent Transcriptional Activation Domains in Yeast
J. Biol. Chem. 2000 275: 14979-14984. [Abstract] [Full Text] [PDF]  

Anette Wärnmark, Jan-Åke Gustafsson, and Anthony P. H. Wright
Architectural Principles for the Structure and Function of the Glucocorticoid Receptor tau 1 Core Activation Domain
J. Biol. Chem. 2000 275: 15014-15018. [Abstract] [Full Text] [PDF]  

Songcang Chen, Junfeng Cui, Karl Nakamura, Ralff C. J. Ribeiro, Brian L. West, and David G. Gardner
Coactivator-Vitamin D Receptor Interactions Mediate Inhibition of the Atrial Natriuretic Peptide Promoter
J. Biol. Chem. 2000 275: 15039-15048. [Abstract] [Full Text] [PDF]  

Erding Hu, Zunxuan Chen, Todd Fredrickson, Yuan Zhu, Robert Kirkpatrick, Gui-Feng Zhang, Kyung Johanson, Chiu-Mei Sung, Ronggang Liu, and James Winkler
Cloning and Characterization of a Novel Human Class I Histone Deacetylase That Functions as a Transcription Repressor
J. Biol. Chem. 2000 275: 15254-15264. [Abstract] [Full Text] [PDF]  

Shyh-Ing Jang, Nevena Karaman-Jurukovska, Maria I. Morasso, Peter M. Steinert, and Nedialka G. Markova
Complex Interactions between Epidermal POU Domain and Activator Protein 1 Transcription Factors Regulate the Expression of the Profilaggrin Gene in Normal Human Epidermal Keratinocytes
J. Biol. Chem. 2000 275: 15295-15304. [Abstract] [Full Text] [PDF]  

Wendy M. Macfarlane, Susan C. Campbell, Lucy J. Elrick, Victoria Oates, Giovanna Bermano, Keith J. Lindley, Albert Aynsley-Green, Mark J. Dunne, Roger F. L. James, and Kevin Docherty
Glucose Regulates Islet Amyloid Polypeptide Gene Transcription in a PDX1- and Calcium-dependent Manner
J. Biol. Chem. 2000 275: 15330-15335. [Abstract] [Full Text] [PDF]  

Nicole A. Becker, Robert J. Kelm, Jr., Julie A. Vrana, Michael J. Getz, and L. James Maher, III
Altered Sensitivity to Single-strand-specific Reagents Associated with the Genomic Vascular Smooth Muscle alpha -Actin Promoter during Myofibroblast Differentiation
J. Biol. Chem. 2000 275: 15384-15391. [Abstract] [Full Text] [PDF]  

Truyen Nguyen, H. C. Huang, and Cecil B. Pickett
Transcriptional Regulation of the Antioxidant Response Element. ACTIVATION BY Nrf2 AND REPRESSION BY MafK
J. Biol. Chem. 2000 275: 15466-15473. [Abstract] [Full Text] [PDF]  

Maria Shnyreva, Daniel S. Schullery, Hideaki Suzuki, Yuji Higaki, and Karol Bomsztyk
Interaction of Two Multifunctional Proteins. HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K AND Y-BOX-BINDING PROTEIN
J. Biol. Chem. 2000 275: 15498-15503. [Abstract] [Full Text] [PDF]  

Kei-ichi Sugiyama, Shingo Izawa, and Yoshiharu Inoue
The Yap1p-dependent Induction of Glutathione Synthesis in Heat Shock Response of Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 15535-15540. [Abstract] [Full Text] [PDF]  

Claudie Lemercier, André Verdel, Bertrand Galloo, Sandrine Curtet, Marie-Paule Brocard, and Saadi Khochbin
mHDA1/HDAC5 Histone Deacetylase Interacts with and Represses MEF2A Transcriptional Activity
J. Biol. Chem. 2000 275: 15594-15599. [Abstract] [Full Text] [PDF]  


RNA: Structure Metabolism and Catalysis:

Nancy Beerens and Ben Berkhout
In Vitro Studies on tRNA Annealing and Reverse Transcription with Mutant HIV-1 RNA Templates
J. Biol. Chem. 2000 275: 15474-15481. [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

Muhammad Talat Nasim, Susanne Jaenecke, Ali Belduz, Heike Kollmus, Leopold Flohé, and John E. G. McCarthy
Eukaryotic Selenocysteine Incorporation Follows a Nonprocessive Mechanism That Competes with Translational Termination
J. Biol. Chem. 2000 275: 14846-14852. [Abstract] [Full Text] [PDF]  

Mark R. Farmery, Simon Allen, Amanda J. Allen, and Neil J. Bulleid
The Role of ERp57 in Disulfide Bond Formation during the Assembly of Major Histocompatibility Complex Class I in a Synchronized Semipermeabilized Cell Translation System
J. Biol. Chem. 2000 275: 14933-14938. [Abstract] [Full Text] [PDF]  

Richard R. Desrosiers, France Gauthier, Julie Lanthier, and Richard Béliveau
Modulation of Rho and Cytoskeletal Protein Attachment to Membranes by a Prenylcysteine Analog
J. Biol. Chem. 2000 275: 14949-14957. [Abstract] [Full Text] [PDF]  

Zhensheng Zhang, Nobuyuki Torii, Akihiro Furusaka, Navara Malayaman, Zongyi Hu, and T. Jake Liang
Structural and Functional Characterization of Interaction between Hepatitis B Virus X Protein and the Proteasome Complex
J. Biol. Chem. 2000 275: 15157-15165. [Abstract] [Full Text] [PDF]  

Caroline R. M. Wilkinson, Katherine Ferrell, Mary Penney, Mairi Wallace, Wolfgang Dubiel, and Colin Gordon
Analysis of a Gene Encoding Rpn10 of the Fission Yeast Proteasome Reveals That the Polyubiquitin-binding Site of This Subunit Is Essential When Rpn12/Mts3 Activity Is Compromised
J. Biol. Chem. 2000 275: 15182-15192. [Abstract] [Full Text] [PDF]  

Angus Chen, Kenneth Wu, Serge Y. Fuchs, Peilin Tan, Carlos Gomez, and Zhen-Qiang Pan
The Conserved RING-H2 Finger of ROC1 Is Required for Ubiquitin Ligation
J. Biol. Chem. 2000 275: 15432-15439. [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Jens Lüders, Jens Demand, Oliver Papp, and Jörg Höhfeld
Distinct Isoforms of the Cofactor BAG-1 Differentially Affect Hsc70 Chaperone Function
J. Biol. Chem. 2000 275: 14817-14823. [Abstract] [Full Text] [PDF]  

Anusri Mitra Bhattacharyya and Paul Horowitz
Alteration Around the Active Site of Rhodanese during Urea-induced Denaturation and Its Implications for Folding
J. Biol. Chem. 2000 275: 14860-14864. [Abstract] [Full Text] [PDF]  

Venkatesha Basrur, Yongsheng Song, Sharlyn J. Mazur, Yuichiro Higashimoto, Jim A. Turpin, William G. Rice, John K. Inman, and Ettore Appella
Inactivation of HIV-1 Nucleocapsid Protein P7 by Pyridinioalkanoyl Thioesters. CHARACTERIZATION OF REACTION PRODUCTS AND PROPOSED MECHANISM OF ACTION
J. Biol. Chem. 2000 275: 14890-14897. [Abstract] [Full Text] [PDF]  

Wanzhi Huang, Zhen Zhang, and Timothy Palzkill
Design of Potent beta -Lactamase Inhibitors by Phage Display of beta -Lactamase Inhibitory Protein
J. Biol. Chem. 2000 275: 14964-14968. [Abstract] [Full Text] [PDF]  

Julie L. Boyer and Gary Ketner
Genetic Analysis of a Potential Zinc-binding Domain of the Adenovirus E4 34k Protein
J. Biol. Chem. 2000 275: 14969-14978. [Abstract] [Full Text] [PDF]  

Anthea L. Newton, Belinda K. Sharpe, Ann Kwan, Joel P. Mackay, and Merlin Crossley
The Transactivation Domain within Cysteine/Histidine-rich Region 1 of CBP Comprises Two Novel Zinc-binding Modules
J. Biol. Chem. 2000 275: 15128-15134. [Abstract] [Full Text] [PDF]  

James A. Huntington, Airlie McCoy, Klara J. Belzar, Xue Y. Pei, Peter G. W. Gettins, and Robin W. Carrell
The Conformational Activation of Antithrombin. A 2.85-Å STRUCTURE OF A FLUORESCEIN DERIVATIVE REVEALS AN ELECTROSTATIC LINK BETWEEN THE HINGE AND HEPARIN BINDING REGIONS
J. Biol. Chem. 2000 275: 15377-15383. [Abstract] [Full Text] [PDF]  

Ryan J. Darling, Raymond W. Ruddon, Fulvio Perini, and Elliott Bedows
Cystine Knot Mutations Affect the Folding of the Glycoprotein Hormone alpha -Subunit. DIFFERENTIAL SECRETION AND ASSEMBLY OF PARTIALLY FOLDED INTERMEDIATES
J. Biol. Chem. 2000 275: 15413-15421. [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Robert H. H. van den Heuvel, Marco W. Fraaije, Andrea Mattevi, and Willem J. H. van Berkel
Asp-170 Is Crucial for the Redox Properties of Vanillyl-alcohol Oxidase
J. Biol. Chem. 2000 275: 14799-14808. [Abstract] [Full Text] [PDF]  

Jan O. Stracke, Mike Hutton, Margaret Stewart, Alberto M. Pendás, Bryan Smith, Carlos López-Otin, Gillian Murphy, and Vera Knäuper
Biochemical Characterization of the Catalytic Domain of Human Matrix Metalloproteinase 19. EVIDENCE FOR A ROLE AS A POTENT BASEMENT MEMBRANE DEGRADING ENZYME
J. Biol. Chem. 2000 275: 14809-14816. [Abstract] [Full Text] [PDF]  

Alexei F. Kisselev, Zhou Songyang, and Alfred L. Goldberg
Why Does Threonine, and Not Serine, Function as the Active Site Nucleophile in Proteasomes?
J. Biol. Chem. 2000 275: 14831-14837. [Abstract] [Full Text] [PDF]  

Zoltán Szeltner, Veronika Renner, and László Polgár
The Noncatalytic beta -Propeller Domain of Prolyl Oligopeptidase Enhances the Catalytic Capability of the Peptidase Domain
J. Biol. Chem. 2000 275: 15000-15005. [Abstract] [Full Text] [PDF]  

Kaisa Lehti, Heli Valtanen, Sara Wickström, Jouko Lohi, and Jorma Keski-Oja
Regulation of Membrane-type-1 Matrix Metalloproteinase Activity by Its Cytoplasmic Domain
J. Biol. Chem. 2000 275: 15006-15013. [Abstract] [Full Text] [PDF]  

Daniela Fattori, Andrea Urbani, Mirko Brunetti, Raffaele Ingenito, Antonello Pessi, Kristine Prendergast, Frank Narjes, Victor G. Matassa, Raffaele De Francesco, and Christian Steinkühler
Probing the Active Site of the Hepatitis C Virus Serine Protease by Fluorescence Resonance Energy Transfer
J. Biol. Chem. 2000 275: 15106-15113. [Abstract] [Full Text] [PDF]  

Patricia A. Ellison, James R. Sellers, and Christine R. Cremo
Kinetics of Smooth Muscle Heavy Meromyosin with One Thiophosphorylated Head
J. Biol. Chem. 2000 275: 15142-15151. [Abstract] [Full Text] [PDF]  

Jolanta Fertala, John R. Vance, Philippe Pourquier, Yves Pommier, and Mary-Ann Bjornsti
Substitutions of Asn-726 in the Active Site of Yeast DNA Topoisomerase I Define Novel Mechanisms of Stabilizing the Covalent Enzyme-DNA Intermediate
J. Biol. Chem. 2000 275: 15246-15253. [Abstract] [Full Text] [PDF]  

Maria A. Argiriadi, Christophe Morisseau, Marvin H. Goodrow, Deanna L. Dowdy, Bruce D. Hammock, and David W. Christianson
Binding of Alkylurea Inhibitors to Epoxide Hydrolase Implicates Active Site Tyrosines in Substrate Activation
J. Biol. Chem. 2000 275: 15265-15270. [Abstract] [Full Text] [PDF]  

Jun-Yang Liou, Song-Kun Shyue, May-Jywan Tsai, Chia-Lin Chung, Kuan-Yu Chu, and Kenneth K. Wu
Colocalization of Prostacyclin Synthase with Prostaglandin H Synthase-1 (PGHS-1) but Not Phorbol Ester-induced PGHS-2 in Cultured Endothelial Cells
J. Biol. Chem. 2000 275: 15314-15320. [Abstract] [Full Text] [PDF]  

Paul Gutwein, Matthias Oleszewski, Sabine Mechtersheimer, Nancy Agmon-Levin, Kerstin Krauss, and Peter Altevogt
Role of Src Kinases in the ADAM-mediated Release of L1 Adhesion Molecule from Human Tumor Cells
J. Biol. Chem. 2000 275: 15490-15497. [Abstract] [Full Text] [PDF]  

Brigita Lenarcic, Gomathi Krishnan, Renata Borukhovich, Brian Ruck, Vito Turk, and Edward Moczydlowski
Saxiphilin, a Saxitoxin-binding Protein with Two Thyroglobulin Type 1 Domains, Is an Inhibitor of Papain-like Cysteine Proteinases
J. Biol. Chem. 2000 275: 15572-15577. [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Salim Merali, Diana Vargas, Matthew Franklin, and Allen B. Clarkson, Jr.
S-Adenosylmethionine and Pneumocystis carinii
J. Biol. Chem. 2000 275: 14958-14963. [Abstract] [Full Text] [PDF]  

Shih-Chia Tso, Sudha K. Shenoy, Byron N. Quinn, and Linda Yu
Subunit IV of Cytochrome bc1 Complex from Rhodobacter sphaeroides. LOCALIZATION OF REGIONS ESSENTIAL FOR INTERACTION WITH THE THREE-SUBUNIT CORE COMPLEX
J. Biol. Chem. 2000 275: 15287-15294. [Abstract] [Full Text] [PDF]  

Rupangi C. Vasavada, Adolfo Garcia-Ocaña, Walter S. Zawalich, Robert L. Sorenson, Pamela Dann, Mushtaq Syed, Linda Ogren, Frank Talamantes, and Andrew F. Stewart
Targeted Expression of Placental Lactogen in the Beta Cells of Transgenic Mice Results in Beta Cell Proliferation, Islet Mass Augmentation, and Hypoglycemia
J. Biol. Chem. 2000 275: 15399-15406. [Abstract] [Full Text] [PDF]  

Montserrat Marí and Arthur I. Cederbaum
CYP2E1 Overexpression in HepG2 Cells Induces Glutathione Synthesis by Transcriptional Activation of gamma -Glutamylcysteine Synthetase
J. Biol. Chem. 2000 275: 15563-15571. [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Jarkko Kortesmaa, Peter Yurchenco, and Karl Tryggvason
Recombinant Laminin-8 (alpha 4beta 1gamma 1). PRODUCTION, PURIFICATION, AND INTERACTIONS WITH INTEGRINS
J. Biol. Chem. 2000 275: 14853-14859. [Abstract] [Full Text] [PDF]  

Tino Hochepied, Wim Van Molle, Franklin G. Berger, Heinz Baumann, and Claude Libert
Involvement of the Acute Phase Protein alpha 1-Acid Glycoprotein in Nonspecific Resistance to a Lethal Gram-negative Infection
J. Biol. Chem. 2000 275: 14903-14909. [Abstract] [Full Text] [PDF]  

Animesh Nandi, Pila Estess, and Mark H. Siegelman
Hyaluronan Anchoring and Regulation on the Surface of Vascular Endothelial Cells Is Mediated through the Functionally Active Form of CD44
J. Biol. Chem. 2000 275: 14939-14948. [Abstract] [Full Text] [PDF]  

Ahmed Faik, Maor Bar-Peled, Amy E. DeRocher, Weiqing Zeng, Robyn M. Perrin, Curtis Wilkerson, Natasha V. Raikhel, and Kenneth Keegstra
Biochemical Characterization and Molecular Cloning of an alpha -1,2-Fucosyltransferase That Catalyzes the Last Step of Cell Wall Xyloglucan Biosynthesis in Pea
J. Biol. Chem. 2000 275: 15082-15089. [Abstract] [Full Text] [PDF]  

Yoshinao Kojima, Satoshi Fukumoto, Keiko Furukawa, Tetsuya Okajima, Joelle Wiels, Keiko Yokoyama, Yasuo Suzuki, Takeshi Urano, Michio Ohta, and Koichi Furukawa
Molecular Cloning of Globotriaosylceramide/CD77 Synthase, a Glycosyltransferase That Initiates the Synthesis of Globo Series Glycosphingolipids
J. Biol. Chem. 2000 275: 15152-15156. [Abstract] [Full Text] [PDF]  

Kazuhisa Iwabuchi, Yongmin Zhang, Kazuko Handa, Donald A. Withers, Pierre Sinaÿ, and Sen-itiroh Hakomori
Reconstitution of Membranes Simulating "Glycosignaling Domain" and Their Susceptibility to Lyso-GM3
J. Biol. Chem. 2000 275: 15174-15181. [Abstract] [Full Text] [PDF]  

Junko Kishibe, Shuhei Yamada, Yukihiko Okada, Junji Sato, Aya Ito, Kaoru Miyazaki, and Kazuyuki Sugahara
Structural Requirements of Heparan Sulfate for the Binding to the Tumor-derived Adhesion Factor/Angiomodulin That Induces Cord-like Structures to ECV-304 Human Carcinoma Cells
J. Biol. Chem. 2000 275: 15321-15329. [Abstract] [Full Text] [PDF]  

Chihiro Sato, Hideyuki Fukuoka, Kaoru Ohta, Tsukasa Matsuda, Rika Koshino, Kazukiyo Kobayashi, Frederic A. Troy, II, and Ken Kitajima
Frequent Occurrence of Pre-existing alpha 2right-arrow8-Linked Disialic and Oligosialic Acids with Chain Lengths Up to 7 Sia Residues in Mammalian Brain Glycoproteins. PREVALENCE REVEALED BY HIGHLY SENSITIVE CHEMICAL METHODS AND ANTI-DI-, OLIGO-, AND POLY-Sia ANTIBODIES SPECIFIC FOR DEFINED CHAIN LENGTHS
J. Biol. Chem. 2000 275: 15422-15431. [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Xin Jie Chen, Bettina E. Bauer, Karl Kuchler, and G. Desmond Clark-Walker
Positive and Negative Control of Multidrug Resistance by the Sit4 Protein Phosphatase in Kluyveromyces lactis
J. Biol. Chem. 2000 275: 14865-14872. [Abstract] [Full Text] [PDF]  

Renata Lopes Souza, Noelle S. Green-Willms, Thomas D. Fox, Alexander Tzagoloff, and Francisco G. Nobrega
Cloning and Characterization of COX18, a Saccharomyces cerevisiae PET Gene Required for the Assembly of Cytochrome Oxidase
J. Biol. Chem. 2000 275: 14898-14902. [Abstract] [Full Text] [PDF]  

Karin Rösch, Dieter Naeher, Vivienne Laird, Veit Goder, and Martin Spiess
The Topogenic Contribution of Uncharged Amino Acids on Signal Sequence Orientation in the Endoplasmic Reticulum
J. Biol. Chem. 2000 275: 14916-14922. [Abstract] [Full Text] [PDF]  

Elena Zvaritch, Peter H. Backx, Frank Jirik, Yoshihiro Kimura, Stella de Leon, Albrecht G. Schmidt, Brian D. Hoit, J. William Lester, Evangelia G. Kranias, and David H. MacLennan
The Transgenic Expression of Highly Inhibitory Monomeric Forms of Phospholamban in Mouse Heart Impairs Cardiac Contractility
J. Biol. Chem. 2000 275: 14985-14991. [Abstract] [Full Text] [PDF]  

Michio Asahi, Edward McKenna, Kazimierz Kurzydlowski, Michihiko Tada, and David H. MacLennan
Physical Interactions between Phospholamban and Sarco(endo)plasmic Reticulum Ca2+-ATPases Are Dissociated by Elevated Ca2+, but Not by Phospholamban Phosphorylation, Vanadate, or Thapsigargin, and Are Enhanced by ATP
J. Biol. Chem. 2000 275: 15034-15038. [Abstract] [Full Text] [PDF]  

David E. Barañano, Herman Wolosker, Byoung-Il Bae, Roxanne K. Barrow, Solomon H. Snyder, and Christopher D. Ferris
A Mammalian Iron ATPase Induced by Iron
J. Biol. Chem. 2000 275: 15166-15173. [Abstract] [Full Text] [PDF]  

Ena Orzech, Shulamit Cohen, Aryeh Weiss, and Benjamin Aroeti
Interactions between the Exocytic and Endocytic Pathways in Polarized Madin-Darby Canine Kidney Cells
J. Biol. Chem. 2000 275: 15207-15219. [Abstract] [Full Text] [PDF]  

Marcel Schmidt, Haiyuan Ding, Visvanathan Ramamurthy, Ishita Mukerji, and Donald Oliver
Nucleotide Binding Activity of SecA Homodimer Is Conformationally Regulated by Temperature and Altered by prlD and azi Mutations
J. Biol. Chem. 2000 275: 15440-15448. [Abstract] [Full Text] [PDF]  

Carolina Landolt-Marticorena, Kelly M. Williams, Judy Correa, Weimin Chen, and Morris F. Manolson
Evidence That the NH2 Terminus of Vph1p, an Integral Subunit of the V0 Sector of the Yeast V-ATPase, Interacts Directly with the Vma1p and Vma13p Subunits of the V1 Sector
J. Biol. Chem. 2000 275: 15449-15457. [Abstract] [Full Text] [PDF]  

Sabine Hunke, Michäel Mourez, Muguette Jéhanno, Elie Dassa, and Erwin Schneider
ATP Modulates Subunit-Subunit Interactions in an ATP-binding Cassette Transporter (MalFGK2) Determined by Site-directed Chemical Cross-linking
J. Biol. Chem. 2000 275: 15526-15534. [Abstract] [Full Text] [PDF]  

Keying Ma, Ronit Simantov, Jing-Chuan Zhang, Roy Silverstein, Katherine A. Hajjar, and Keith R. McCrae
High Affinity Binding of beta 2-Glycoprotein I to Human Endothelial Cells Is Mediated by Annexin II
J. Biol. Chem. 2000 275: 15541-15548. [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Kotha Subbaramaiah, Janice C. Hart, Larry Norton, and Andrew J. Dannenberg
Microtubule-interfering Agents Stimulate the Transcription of Cyclooxygenase-2. EVIDENCE FOR INVOLVEMENT OF ERK1/2 AND p38 MITOGEN-ACTIVATED PROTEIN KINASE PATHWAYS
J. Biol. Chem. 2000 275: 14838-14845. [Abstract] [Full Text] [PDF]  

Giorgia Razzini, Anna Brancaccio, Mark A. Lemmon, Simone Guarnieri, and Marco Falasca
The Role of the Pleckstrin Homology Domain in Membrane Targeting and Activation of Phospholipase Cbeta 1
J. Biol. Chem. 2000 275: 14873-14881. [Abstract] [Full Text] [PDF]  

Raja Bhattacharyya and Philip B. Wedegaertner
Galpha 13 Requires Palmitoylation for Plasma Membrane Localization, Rho-dependent Signaling, and Promotion of p115-RhoGEF Membrane Binding
J. Biol. Chem. 2000 275: 14992-14999. [Abstract] [Full Text] [PDF]  

Douglas L. Anders, Tana Blevins, Corigan T. Smothers, and John J. Woodward
Reduced Ethanol Inhibition of N-Methyl-D-aspartate Receptors by Deletion of the NR1 C0 Domain or Overexpression of alpha -Actinin-2 Proteins
J. Biol. Chem. 2000 275: 15019-15024. [Abstract] [Full Text] [PDF]  

Dagmar Kulms, Birgit Pöppelmann, and Thomas Schwarz
Ultraviolet Radiation-induced Interleukin 6 Release in HeLa Cells Is Mediated via Membrane Events in a DNA Damage-independent Way
J. Biol. Chem. 2000 275: 15060-15066. [Abstract] [Full Text] [PDF]  

Seung Hyun Yoo and Choon Ju Jeon
Inositol 1,4,5-Trisphosphate Receptor/Ca2+ Channel Modulatory Role of Chromogranin A, a Ca2+ Storage Protein of Secretory Granules
J. Biol. Chem. 2000 275: 15067-15073. [Abstract] [Full Text] [PDF]  

Balaka Das, Xiaodong Shu, Gwo-Jen Day, Jaewon Han, U. Murali Krishna, John R. Falck, and Daniel Broek
Control of Intramolecular Interactions between the Pleckstrin Homology and Dbl Homology Domains of Vav and Sos1 Regulates Rac Binding
J. Biol. Chem. 2000 275: 15074-15081. [Abstract] [Full Text] [PDF]  

Cong S. Zong, Joseph Chan, David E. Levy, Curt Horvath, Henry B. Sadowski, and Lu-Hai Wang
Mechanism of STAT3 Activation by Insulin-like Growth Factor I Receptor
J. Biol. Chem. 2000 275: 15099-15105. [Abstract] [Full Text] [PDF]  

Isabelle Millet, Roderick J. Phillips, Robert S. Sherwin, Sankar Ghosh, Reinhard E. Voll, Richard A. Flavell, Agnès Vignery, and Mercedes Rincón
Inhibition of NF-kappa B Activity and Enhancement of Apoptosis by the Neuropeptide Calcitonin Gene-related Peptide
J. Biol. Chem. 2000 275: 15114-15121. [Abstract] [Full Text] [PDF]  

Linda B. Moore, Derek J. Parks, Stacey A. Jones, Randy K. Bledsoe, Thomas G. Consler, Julie B. Stimmel, Bryan Goodwin, Christopher Liddle, Steven G. Blanchard, Timothy M. Willson, Jon L. Collins, and Steven A. Kliewer
Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands
J. Biol. Chem. 2000 275: 15122-15127. [Abstract] [Full Text] [PDF]  

Marie-Christine Broillet
A Single Intracellular Cysteine Residue Is Responsible for the Activation of the Olfactory Cyclic Nucleotide-gated Channel by NO
J. Biol. Chem. 2000 275: 15135-15141. [Abstract] [Full Text] [PDF]  

Patricia Renard, Yann Percherancier, Mathias Kroll, Dominique Thomas, Jean-Louis Virelizier, Fernando Arenzana-Seisdedos, and Françoise Bachelerie
Inducible NF-kappa B Activation Is Permitted by Simultaneous Degradation of Nuclear Ikappa Balpha
J. Biol. Chem. 2000 275: 15193-15199. [Abstract] [Full Text] [PDF]  

Gábor Szalai, György Csordás, Basil M. Hantash, Andrew P. Thomas, and György Hajnóczky
Calcium Signal Transmission between Ryanodine Receptors and Mitochondria
J. Biol. Chem. 2000 275: 15305-15313. [Abstract] [Full Text] [PDF]  

Elles Feiken, Ingrid van Etten, Martijn F. B. G. Gebbink, Wouter H. Moolenaar, and Gerben C. M. Zondag
Intramolecular Interactions between the Juxtamembrane Domain and Phosphatase Domains of Receptor Protein-tyrosine Phosphatase RPTPµ. REGULATION OF CATALYTIC ACTIVITY
J. Biol. Chem. 2000 275: 15350-15356. [Abstract] [Full Text] [PDF]  

Jean-Marie Darbon, Marie Penary, Nathalie Escalas, Fabrice Casagrande, Françoise Goubin-Gramatica, Caroline Baudouin, and Bernard Ducommun
Distinct Chk2 Activation Pathways Are Triggered by Genistein and DNA-damaging Agents in Human Melanoma Cells
J. Biol. Chem. 2000 275: 15363-15369. [Abstract] [Full Text] [PDF]  

Hideto Hoshino, Akira Kobayashi, Minoru Yoshida, Nobuaki Kudo, Tatsuya Oyake, Hozumi Motohashi, Norio Hayashi, Masayuki Yamamoto, and Kazuhiko Igarashi
Oxidative Stress Abolishes Leptomycin B-sensitive Nuclear Export of Transcription Repressor Bach2 That Counteracts Activation of Maf Recognition Element
J. Biol. Chem. 2000 275: 15370-15376. [Abstract] [Full Text] [PDF]  

Bruce S. Hostager, Ian M. Catlett, and Gail A. Bishop
Recruitment of CD40 and Tumor Necrosis Factor Receptor-associated Factors 2 and 3 to Membrane Microdomains during CD40 Signaling
J. Biol. Chem. 2000 275: 15392-15398. [Abstract] [Full Text] [PDF]  

Lisa A. Madge and Jordan S. Pober
A Phosphatidylinositol 3-Kinase/Akt Pathway, Activated by Tumor Necrosis Factor or Interleukin-1, Inhibits Apoptosis but Does Not Activate NFkappa B in Human Endothelial Cells
J. Biol. Chem. 2000 275: 15458-15465. [Abstract] [Full Text] [PDF]  

Chundong Yu, Fen Wang, Mikio Kan, Chengliu Jin, Richard B. Jones, Michael Weinstein, Chu-Xia Deng, and Wallace L. McKeehan
Elevated Cholesterol Metabolism and Bile Acid Synthesis in Mice Lacking Membrane Tyrosine Kinase Receptor FGFR4
J. Biol. Chem. 2000 275: 15482-15489. [Abstract] [Full Text] [PDF]  

Yoshikatsu Matsubayashi and Youji Sakagami
120- and 160-kDa Receptors for Endogenous Mitogenic Peptide, Phytosulfokine-alpha , in Rice Plasma Membranes
J. Biol. Chem. 2000 275: 15520-15525. [Abstract] [Full Text] [PDF]  

Diego L. Medina, María-José Toro, and Pilar Santisteban
Somatostatin Interferes with Thyrotropin-induced G1-S Transition Mediated by cAMP-dependent Protein Kinase and Phosphatidylinositol 3-Kinase. INVOLVEMENT OF RhoA AND CYCLIN E·CYCLIN-DEPENDENT KINASE 2 COMPLEXES
J. Biol. Chem. 2000 275: 15549-15556. [Abstract] [Full Text] [PDF]  

Jun Tanikawa, Emi Ichikawa-Iwata, Chie Kanei-Ishii, Akira Nakai, Shu-ichi Matsuzawa, John C. Reed, and Shunsuke Ishii
p53 Suppresses the c-Myb-induced Activation of Heat Shock Transcription Factor 3
J. Biol. Chem. 2000 275: 15578-15585. [Abstract] [Full Text] [PDF]  

M. Showkat Ali, Peter P. Sayeski, and Kenneth E. Bernstein
Jak2 Acts as Both a STAT1 Kinase and as a Molecular Bridge Linking STAT1 to the Angiotensin II AT1 Receptor
J. Biol. Chem. 2000 275: 15586-15593. [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Qingshen Gao, Ajay Kumar, Seetha Srinivasan, Latika Singh, Hideyuki Mukai, Yoshitaka Ono, David E. Wazer, and Vimla Band
PKN Binds and Phosphorylates Human Papillomavirus E6 Oncoprotein
J. Biol. Chem. 2000 275: 14824-14830. [Abstract] [Full Text] [PDF]  

Isabelle Mouyna, Thierry Fontaine, Marina Vai, Michel Monod, William A. Fonzi, Michel Diaquin, Laura Popolo, Robbert P. Hartland, and Jean-Paul Latgé
Glycosylphosphatidylinositol-anchored Glucanosyltransferases Play an Active Role in the Biosynthesis of the Fungal Cell Wall
J. Biol. Chem. 2000 275: 14882-14889. [Abstract] [Full Text] [PDF]  

Jia Shi and Stephen P. Sugrue
Dissection of Protein Linkage between Keratins and Pinin, a Protein with Dual Location at Desmosome-Intermediate Filament Complex and in the Nucleus
J. Biol. Chem. 2000 275: 14910-14915. [Abstract] [Full Text] [PDF]  

Dianhua Qiao, Weixing Chen, Elias D. Stratagoules, and Jesse D. Martinez
Bile Acid-induced Activation of Activator Protein-1 Requires Both Extracellular Signal-regulated Kinase and Protein Kinase C Signaling
J. Biol. Chem. 2000 275: 15090-15098. [Abstract] [Full Text] [PDF]  

Philip Ian Padilla, Akihiro Wada, Kinnosuke Yahiro, Miyuki Kimura, Takuro Niidome, Haruhiko Aoyagi, Atsushi Kumatori, Masanobu Anami, Tomoyoshi Hayashi, Jun-ichi Fujisawa, Haruo Saito, Joel Moss, and Toshiya Hirayama
Morphologic Differentiation of HL-60 Cells Is Associated with Appearance of RPTPbeta and Induction of Helicobacter pylori VacA Sensitivity
J. Biol. Chem. 2000 275: 15200-15206. [Abstract] [Full Text] [PDF]  

David J. Abraham, Xu Shiwen, Carol M. Black, Susan Sa, Yili Xu, and Andrew Leask
Tumor Necrosis Factor alpha  Suppresses the Induction of Connective Tissue Growth Factor by Transforming Growth Factor-beta in Normal and Scleroderma Fibroblasts
J. Biol. Chem. 2000 275: 15220-15225. [Abstract] [Full Text] [PDF]  

Vincenzo De Laurenzi, Giuseppe Raschellá, Daniela Barcaroli, Margherita Annicchiarico-Petruzzelli, Marco Ranalli, Maria Valeria Catani, Barbara Tanno, Antonio Costanzo, Massimo Levrero, and Gerry Melino
Induction of Neuronal Differentiation by p73 in a Neuroblastoma Cell Line
J. Biol. Chem. 2000 275: 15226-15231. [Abstract] [Full Text] [PDF]  

George F. Gao, Benjamin E. Willcox, Jessica R. Wyer, Jonathan M. Boulter, Christopher A. O'Callaghan, Katsumi Maenaka, David I. Stuart, E. Yvonne Jones, P. Anton Van Der Merwe, John I. Bell, and Bent K. Jakobsen
Classical and Nonclassical Class I Major Histocompatibility Complex Molecules Exhibit Subtle Conformational Differences That Affect Binding to CD8alpha alpha
J. Biol. Chem. 2000 275: 15232-15238. [Abstract] [Full Text] [PDF]  

Weidong Zhu, Yunzeng Zou, Ichiro Shiojima, Sumiyo Kudoh, Ruichi Aikawa, Dobun Hayashi, Miho Mizukami, Haruhiro Toko, Futoshi Shibasaki, Yoshio Yazaki, Ryozo Nagai, and Issei Komuro
Ca2+/Calmodulin-dependent Kinase II and Calcineurin Play Critical Roles in Endothelin-1-induced Cardiomyocyte Hypertrophy
J. Biol. Chem. 2000 275: 15239-15245. [Abstract] [Full Text] [PDF]  

Andrew J. Bean, Svend Davanger, Marian F. Chou, Brenda Gerhardt, Susan Tsujimoto, and YuChieh Chang
Hrs-2 Regulates Receptor-mediated Endocytosis via Interactions with Eps15
J. Biol. Chem. 2000 275: 15271-15278. [Abstract] [Full Text] [PDF]  

Mingming Hao and Frederick R. Maxfield
Characterization of Rapid Membrane Internalization and Recycling
J. Biol. Chem. 2000 275: 15279-15286. [Abstract] [Full Text] [PDF]  

Michael T. Eby, Alan Jasmin, Arvind Kumar, Kiran Sharma, and Preet M. Chaudhary
TAJ, a Novel Member of the Tumor Necrosis Factor Receptor Family, Activates the c-Jun N-terminal Kinase Pathway and Mediates Caspase-independent Cell Death
J. Biol. Chem. 2000 275: 15336-15342. [Abstract] [Full Text] [PDF]  

Richard Chikara Koya, Hisakazu Fujita, Shigeomi Shimizu, Makoto Ohtsu, Masato Takimoto, Yoshihide Tsujimoto, and Noboru Kuzumaki
Gelsolin Inhibits Apoptosis by Blocking Mitochondrial Membrane Potential Loss and Cytochrome c Release
J. Biol. Chem. 2000 275: 15343-15349. [Abstract] [Full Text] [PDF]  

Christian Schmitz, Michael Gotthardt, Stephan Hinderlich, Jörg-Robert Leheste, Volkmar Gross, Henrik Vorum, Erik Ilsø Christensen, Friedrich C. Luft, Saori Takahashi, and Thomas E. Willnow
Normal Blood Pressure and Plasma Renin Activity in Mice Lacking the Renin-binding Protein, a Cellular Renin Inhibitor
J. Biol. Chem. 2000 275: 15357-15362. [Abstract] [Full Text] [PDF]  

Chingwen Ying and Don-Hei Lin
Estrogen-modulated Estrogen Receptor·Pit-1 Protein Complex Formation and Prolactin Gene Activation Require Novel Protein Synthesis
J. Biol. Chem. 2000 275: 15407-15412. [Abstract] [Full Text] [PDF]  

Zubaida Saifudeen, Hong Du, Susana Dipp, and Samir S. El-Dahr
The Bradykinin Type 2 Receptor Is a Target for p53-mediated Transcriptional Activation
J. Biol. Chem. 2000 275: 15557-15562. [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Meenu Kesarwani, Mohammad Azam, K. Natarajan, Anuradha Mehta, and Asis Datta
Oxalate decarboxylase from Collybia velutipes: molecular cloning and its overexpression to confer resistance to fungal infection in transgenic tobacco and tomato.
J. Biol. Chem. 2000 275: 15600. [Full Text] [PDF]  

Loretta Dorstyn, Stuart H. Read, Leonie M. Quinn, Helena Richardson, and Sharad Kumar
DECAY, a novel Drosophila caspase related to mammalian caspase-3 and caspase-7.
J. Biol. Chem. 2000 275: 15600. [Full Text] [PDF]  


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