Editorial:

JBC electronic submission required (Starting September 1, 2000)
J. Biol. Chem. 2000 275: 20957. [Full Text] [PDF]  

Accelerated Publications:

Uriel M. Malyankar, Marta Scatena, Katherine L. Suchland, Theodore J. Yun, Edward A. Clark, and Cecilia M. Giachelli

Osteoprotegerin Is an _v3-induced, NF-B-dependent Survival Factor for Endothelial Cells
J. Biol. Chem. 2000 275: 20959-20962. [Abstract] [Full Text] [PDF]  

Yoh-ichi Kawabe, Masayuki Seki, Takahiko Seki, Wen-Sheng Wang, Osamu Imamura, Yasuhiro Furuichi, Hisato Saitoh, and Takemi Enomoto

Covalent Modification of the Werner's Syndrome Gene Product with the Ubiquitin-related Protein, SUMO-1
J. Biol. Chem. 2000 275: 20963-20966. [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Anne F. Nichols, Toshiki Itoh, Jay A. Graham, Wei Liu, Masaru Yamaizumi, and Stuart Linn

Human Damage-specific DNA-binding Protein p48. CHARACTERIZATION OF XPE MUTATIONS AND REGULATION FOLLOWING UV IRRADIATION
J. Biol. Chem. 2000 275: 21422-21428. [Abstract] [Full Text] [PDF]  

Wei Liu, Anne F. Nichols, Jay A. Graham, Rachel Dualan, Alex Abbas, and Stuart Linn

Nuclear Transport of Human DDB Protein Induced by Ultraviolet Light
J. Biol. Chem. 2000 275: 21429-21434. [Abstract] [Full Text] [PDF]  

Naijie Jing, Christophe Marchand, Jie Liu, Rahul Mitra, Michael E. Hogan, and Yves Pommier

Mechanism of Inhibition of HIV-1 Integrase by G-tetrad-forming Oligonucleotides in Vitro
J. Biol. Chem. 2000 275: 21460-21467. [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Chinmay K. Mukhopadhyay, Barsanjit Mazumder, and Paul L. Fox

Role of Hypoxia-inducible Factor-1 in Transcriptional Activation of Ceruloplasmin by Iron Deficiency
J. Biol. Chem. 2000 275: 21048-21054. [Abstract] [Full Text] [PDF]  

Maria Cervellera, Giuseppe Raschella, Giorgia Santilli, Barbara Tanno, Andrea Ventura, Camillo Mancini, Cinzia Sevignani, Bruno Calabretta, and Arturo Sala

Direct Transactivation of the Anti-apoptotic Gene Apolipoprotein J (Clusterin) by B-MYB
J. Biol. Chem. 2000 275: 21055-21060. [Abstract] [Full Text] [PDF]  

John J. E. Haddad, Richard E. Olver, and Stephen C. Land

Antioxidant/Pro-oxidant Equilibrium Regulates HIF-1 and NF-B Redox Sensitivity. EVIDENCE FOR INHIBITION BY GLUTATHIONE OXIDATION IN ALVEOLAR EPITHELIAL CELLS
J. Biol. Chem. 2000 275: 21130-21139. [Abstract] [Full Text] [PDF]  

Joanne I. Adamkewicz, Christopher G. F. Mueller, Karin E. Hansen, Wendy A. Prud'homme, and Jeremy Thorner

Purification and Enzymic Properties of Mot1 ATPase, a Regulator of Basal Transcription in the Yeast Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 21158-21168. [Abstract] [Full Text] [PDF]  

Zhiyong Yang, Nawarat Wara-aswapati, Changmin Chen, Junichi Tsukada, and Philip E. Auron

NF-IL6 (C/EBP) Vigorously Activates il1b Gene Expression via a Spi-1 (PU.1) Protein-Protein Tether
J. Biol. Chem. 2000 275: 21272-21277. [Abstract] [Full Text] [PDF]  

Sumito Ogawa, Masayo Fujita, Yasunori Ishii, Hiroshi Tsurukami, Masami Hirabayashi, Kazuhiro Ikeda, Akira Orimo, Takayuki Hosoi, Masatsugu Ueda, Toshitaka Nakamura, Yasuyoshi Ouchi, Masami Muramatsu, and Satoshi Inoue

Impaired Estrogen Sensitivity in Bone by Inhibiting Both Estrogen Receptor  and  Pathways
J. Biol. Chem. 2000 275: 21372-21379. [Abstract] [Full Text] [PDF]  

Paul R. Stabach and Jon S. Morrow

Identification and Characterization of V Spectrin, a Mammalian Ortholog of Drosophila _H Spectrin
J. Biol. Chem. 2000 275: 21385-21395. [Abstract] [Full Text] [PDF] Supplemental Data  

Adele F. Holloway, Filomena Occhiodoro, Gerhard Mittler, Michael Meisterernst, and M. Frances Shannon

Functional Interaction between the HIV Transactivator Tat and the Transcriptional Coactivator PC4 in T Cells
J. Biol. Chem. 2000 275: 21668-21677. [Abstract] [Full Text] [PDF]  

Marion Steffensky, Shu-Ming Li, and Lutz Heide

Cloning, Overexpression, and Purification of Novobiocic Acid Synthetase from Streptomyces spheroides NCIMB 11891
J. Biol. Chem. 2000 275: 21754-21760. [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Franco Pagani, Emanuele Buratti, Cristiana Stuani, Maurizio Romano, Elisabetta Zuccato, Martina Niksic, Luisella Giglio, Dino Faraguna, and Francisco E. Baralle

Splicing Factors Induce Cystic Fibrosis Transmembrane Regulator Exon 9 Skipping through a Nonevolutionary Conserved Intronic Element
J. Biol. Chem. 2000 275: 21041-21047. [Abstract] [Full Text] [PDF]  

Frédéric Ducongé, Carmelo Di Primo, and Jean-Jacques Toulmé

Is a Closing "GA Pair" a Rule for Stable Loop-Loop RNA Complexes?
J. Biol. Chem. 2000 275: 21287-21294. [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Niels P. N. Emmerich, Alexander K. Nussbaum, Stefan Stevanovic, Martin Priemer, René E. M. Toes, Hans-Georg Rammensee, and Hansjörg Schild

The Human 26 S and 20 S Proteasomes Generate Overlapping but Different Sets of Peptide Fragments from a Model Protein Substrate
J. Biol. Chem. 2000 275: 21140-21148. [Abstract] [Full Text] [PDF]  

Cornelia M. Wilson, Mark R. Farmery, and Neil J. Bulleid

Pivotal Role of Calnexin and Mannose Trimming in Regulating the Endoplasmic Reticulum-associated Degradation of Major Histocompatibility Complex Class I Heavy Chain
J. Biol. Chem. 2000 275: 21224-21232. [Abstract] [Full Text] [PDF]  

Bing L. Yang, Liu Cao, Chris Kiani, Vivian Lee, Yaou Zhang, Mark E. Adams, and Burton B. Yang

Tandem Repeats Are Involved in G1 Domain Inhibition of Versican Expression and Secretion and the G3 Domain Enhances Glycosaminoglycan Modification and Product Secretion via the Complement-binding Protein-like Motif
J. Biol. Chem. 2000 275: 21255-21261. [Abstract] [Full Text] [PDF]  

Matthew P. Pando and Inder M. Verma

Signal-dependent and -independent Degradation of Free and NF-B-bound IB
J. Biol. Chem. 2000 275: 21278-21286. [Abstract] [Full Text] [PDF]  

Adriana M. Cassina, Roberto Hodara, José M. Souza, Leonor Thomson, Laura Castro, Harry Ischiropoulos, Bruce A. Freeman, and Rafael Radi

Cytochrome c Nitration by Peroxynitrite
J. Biol. Chem. 2000 275: 21409-21415. [Abstract] [Full Text] [PDF]  

Poul Henning Jensen, Khalid Islam, John Kenney, Morten Schallburg Nielsen, John Power, and Wei Ping Gai

Microtubule-associated Protein 1B Is a Component of Cortical Lewy Bodies and Binds -Synuclein Filaments
J. Biol. Chem. 2000 275: 21500-21507. [Abstract] [Full Text] [PDF]  

Kristin Breitschopf, Andreas M. Zeiher, and Stefanie Dimmeler

Ubiquitin-mediated Degradation of the Proapoptotic Active Form of Bid. A FUNCTIONAL CONSEQUENCE ON APOPTOSIS INDUCTION
J. Biol. Chem. 2000 275: 21648-21652. [Abstract] [Full Text] [PDF]  

Yusuke Furukawa, Satsuki Iwase, Jiro Kikuchi, Yasuhito Terui, Mitsuru Nakamura, Hisashi Yamada, Yasuhiko Kano, and Michio Matsuda

Phosphorylation of Bcl-2 Protein by CDC2 Kinase during G₂/M Phases and Its Role in Cell Cycle Regulation
J. Biol. Chem. 2000 275: 21661-21667. [Abstract] [Full Text] [PDF]  

Aaron M. Domina, Jessica H. Smith, and Ruth W. Craig

Myeloid Cell Leukemia 1 Is Phosphorylated through Two Distinct Pathways, One Associated with Extracellular Signal-regulated Kinase Activation and the Other with G₂/M Accumulation or Protein Phosphatase 1/2A Inhibition
J. Biol. Chem. 2000 275: 21688-21694. [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Charles E. Petersen, Chung-Eun Ha, Krishna Harohalli, Jimmy B. Feix, and Nadhipuram V. Bhagavan

A Dynamic Model for Bilirubin Binding to Human Serum Albumin
J. Biol. Chem. 2000 275: 20985-20995. [Abstract] [Full Text] [PDF]  

Olav Michael Andersen, Lisa Lystbæk Christensen, Peter Astrup Christensen, Esben S. Sørensen, Christian Jacobsen, Søren K. Moestrup, Michael Etzerodt, and Hans Christian Thøgersen

Identification of the Minimal Functional Unit in the Low Density Lipoprotein Receptor-related Protein for Binding the Receptor-associated Protein (RAP). A CONSERVED ACIDIC RESIDUE IN THE COMPLEMENT-TYPE REPEATS IS IMPORTANT FOR RECOGNITION OF RAP
J. Biol. Chem. 2000 275: 21017-21024. [Abstract] [Full Text] [PDF]  

Mitsuru Haniu, Paul Denis, Yunjen Young, Elizabeth A. Mendiaz, Janis Fuller, John O. Hui, Brian D. Bennett, Steven Kahn, Sandra Ross, Teresa Burgess, Viswanatham Katta, Gary Rogers, Robert Vassar, and Martin Citron

Characterization of Alzheimer's -Secretase Protein BACE. A PEPSIN FAMILY MEMBER WITH UNUSUAL PROPERTIES
J. Biol. Chem. 2000 275: 21099-21106. [Abstract] [Full Text] [PDF]  

Sophia Diamant, Anat Peres Ben-Zvi, Bernd Bukau, and Pierre Goloubinoff

Size-dependent Disaggregation of Stable Protein Aggregates by the DnaK Chaperone Machinery
J. Biol. Chem. 2000 275: 21107-21113. [Abstract] [Full Text] [PDF]  

Hiroshi Kobayashi, Yasuyuki Hirashima, Guang Wei Sun, Michio Fujie, Takashi Nishida, Masaharu Takigawa, and Toshihiko Terao

Identity of Urinary Trypsin Inhibitor-binding Protein to Link Protein
J. Biol. Chem. 2000 275: 21185-21191. [Abstract] [Full Text] [PDF]  

Matthew Jones, Jaswir Basran, Michael J. Sutcliffe, J. Günter Grossmann, and Nigel S. Scrutton

X-ray Scattering Studies of Methylophilus methylotrophus (sp. W₃A₁) Electron-transferring Flavoprotein. EVIDENCE FOR MULTIPLE CONFORMATIONAL STATES AND AN INDUCED FIT MECHANISM FOR ASSEMBLY WITH TRIMETHYLAMINE DEHYDROGENASE
J. Biol. Chem. 2000 275: 21349-21354. [Abstract] [Full Text] [PDF]  

Emmanuel Bissé, Nathalie Zorn, Irene Heinrichs, Antonin Eigel, Alain Van Dorsselaer, Heinrich Wieland, Jean Kister, and Michael C. Marden

Characterization of a New Electrophoretically Silent Hemoglobin Variant. Hb Saale OR ₂₂ 84(EF8)Thr  Ala
J. Biol. Chem. 2000 275: 21380-21384. [Abstract] [Full Text] [PDF]  

Germaine Fuh, M. Teresa Pisabarro, Ying Li, Clifford Quan, Laurence A. Lasky, and Sachdev S. Sidhu

Analysis of PDZ Domain-Ligand Interactions Using Carboxyl-terminal Phage Display
J. Biol. Chem. 2000 275: 21486-21491. [Abstract] [Full Text] [PDF]  

Chichi Huang, Qun Zang, Junichi Takagi, and Timothy A. Springer

Structural and Functional Studies with Antibodies to the Integrin 2 Subunit. A MODEL FOR THE I-LIKE DOMAIN
J. Biol. Chem. 2000 275: 21514-21524. [Abstract] [Full Text] [PDF]  

Marie-Bernard Lascombe, Christophe Grégoire, Pascal Poncet, Gisele A. Tavares, Isabelle Rosinski-Chupin, Jacques Rabillon, Hany Goubran-Botros, Jean-Claude Mazié, Bernard David, and Pedro M. Alzari

Crystal Structure of the Allergen Equ c 1. A DIMERIC LIPOCALIN WITH RESTRICTED IgE-REACTIVE EPITOPES
J. Biol. Chem. 2000 275: 21572-21577. [Abstract] [Full Text] [PDF]  

Nathalie Germain, Karine Mérienne, Sophie Zinn-Justin, Jean-Claude Boulain, Frédéric Ducancel, and André Ménez

Molecular and Structural Basis of the Specificity of a Neutralizing Acetylcholine Receptor-mimicking Antibody, Using Combined Mutational and Molecular Modeling Analyses
J. Biol. Chem. 2000 275: 21578-21586. [Abstract] [Full Text] [PDF]  

Taeho Kim, Sang Gyu Park, Jee Eun Kim, Wongi Seol, Young-Gyu Ko, and Sunghoon Kim

Catalytic Peptide of Human Glutaminyl-tRNA Synthetase Is Essential for Its Assembly to the Aminoacyl-tRNA Synthetase Complex
J. Biol. Chem. 2000 275: 21768-21772. [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Isabelle Schepens, Kenth Johansson, Paulette Decottignies, Maggaly Gillibert, Masakazu Hirasawa, David B. Knaff, and Myroslawa Miginiac-Maslow

Inhibition of the Thioredoxin-dependent Activation of the NADP-malate Dehydrogenase and Cofactor Specificity
J. Biol. Chem. 2000 275: 20996-21001. [Abstract] [Full Text] [PDF]  

Rhona E. Feltzer, Robert D. Gray, William L. Dean, and William M. Pierce, Jr.

Alkaline Proteinase Inhibitor of Pseudomonas aeruginosa. INTERACTION OF NATIVE AND N-TERMINALLY TRUNCATED INHIBITOR PROTEINS WITH PSEUDOMONAS METALLOPROTEINASES
J. Biol. Chem. 2000 275: 21002-21009. [Abstract] [Full Text] [PDF]  

Rita Mukhopadhyay, Jin Shi, and Barry P. Rosen

Purification and Characterization of Acr2p, the Saccharomyces cerevisiae Arsenate Reductase
J. Biol. Chem. 2000 275: 21149-21157. [Abstract] [Full Text] [PDF]  

Xiaoling Zhou, Michael G. Espey, James X. Chen, Lorne J. Hofseth, Katrina M. Miranda, S. Perwez Hussain, David A. Wink, and Curtis C. Harris

Inhibitory Effects of Nitric Oxide and Nitrosative Stress on Dopamine--Hydroxylase
J. Biol. Chem. 2000 275: 21241-21246. [Abstract] [Full Text] [PDF]  

Alexander G. Yakovlev, Geping Wang, Bogdan A. Stoica, Hamid A. Boulares, Alexander Y. Spoonde, Koichiro Yoshihara, and Mark E. Smulson

A Role of the Ca²⁺/Mg²⁺-dependent Endonuclease in Apoptosis and Its Inhibition by Poly(ADP-ribose) Polymerase
J. Biol. Chem. 2000 275: 21302-21308. [Abstract] [Full Text] [PDF]  

Cyrus Munshi, Robert Aarhus, Richard Graeff, Timothy F. Walseth, David Levitt, and Hon Cheung Lee

Identification of the Enzymatic Active Site of CD38 by Site-directed Mutagenesis
J. Biol. Chem. 2000 275: 21566-21571. [Abstract] [Full Text] [PDF]  

Bharat L. Dixit, Ganesaratnam K. Balendiran, Stanley J. Watowich, Sanjay Srivastava, Kota V. Ramana, J. Mark Petrash, Aruni Bhatnagar, and Satish K. Srivastava

Kinetic and Structural Characterization of the Glutathione-binding Site of Aldose Reductase
J. Biol. Chem. 2000 275: 21587-21595. [Abstract] [Full Text] [PDF]  

Cynthia Perreault-Micale, Alexander D. Shushan, and Lynne M. Coluccio

Truncation of a Mammalian Myosin I Results in Loss of Ca²⁺-sensitive Motility
J. Biol. Chem. 2000 275: 21618-21623. [Abstract] [Full Text] [PDF]  

Michael A. Geeves, Cynthia Perreault-Micale, and Lynne M. Coluccio

Kinetic Analyses of a Truncated Mammalian Myosin I Suggest a Novel Isomerization Event Preceding Nucleotide Binding
J. Biol. Chem. 2000 275: 21624-21630. [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Amir Aharoni, Lev Weiner, Michael Ottolenghi, and Mordechai Sheves

Bacteriorhodpsin Experiences Light-induced Conformational Alterations in Nonisomerizable C₁₃=C₁₄ Pigments. A STUDY WITH EPR
J. Biol. Chem. 2000 275: 21010-21016. [Abstract] [Full Text] [PDF]  

Axel Magalon and August Böck

Analysis of the HypC-HycE Complex, a Key Intermediate in the Assembly of the Metal Center of the Escherichia coli Hydrogenase 3
J. Biol. Chem. 2000 275: 21114-21120. [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Hiroshi Kitagawa, Masaki Fujita, Nobue Ito, and Kazuyuki Sugahara

Molecular Cloning and Expression of a Novel Chondroitin 6-O-Sulfotransferase
J. Biol. Chem. 2000 275: 21075-21080. [Abstract] [Full Text] [PDF]  

Yohei Maeshima, Pablo C. Colorado, Adriana Torre, Kathryn A. Holthaus, James A. Grunkemeyer, Mark B. Ericksen, Helmut Hopfer, Yingwen Xiao, Isaac E. Stillman, and Raghu Kalluri

Distinct Antitumor Properties of a Type IV Collagen Domain Derived from Basement Membrane
J. Biol. Chem. 2000 275: 21340-21348. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Joelle M. Onorato, Alicia J. Jenkins, Suzanne R. Thorpe, and John W. Baynes

Pyridoxamine, an Inhibitor of Advanced Glycation Reactions, Also Inhibits Advanced Lipoxidation Reactions. MECHANISM OF ACTION OF PYRIDOXAMINE
J. Biol. Chem. 2000 275: 21177-21184. [Abstract] [Full Text] [PDF]  

Markus Goese, Wolfgang Eisenreich, Ernst Kupfer, Wolfgang Weber, and Adelbert Bacher

Biosynthetic Origin of Hydrogen Atoms in the Lipase Inhibitor Lipstatin
J. Biol. Chem. 2000 275: 21192-21196. [Abstract] [Full Text] [PDF]  

Kristin A. Waite and Dennis E. Vance

Why Expression of Phosphatidylethanolamine N-Methyltransferase Does Not Rescue Chinese Hamster Ovary Cells That Have an Impaired CDP-Choline Pathway
J. Biol. Chem. 2000 275: 21197-21202. [Abstract] [Full Text] [PDF]  

Kalliopi N. Liadaki, Tong Liu, Shangzhe Xu, Brian Y. Ishida, Philippe N. Duchateaux, Jonathan P. Krieger, John Kane, Monty Krieger, and Vassilis I. Zannis

Binding of High Density Lipoprotein (HDL) and Discoidal Reconstituted HDL to the HDL Receptor Scavenger Receptor Class B Type I. EFFECT OF LIPID ASSOCIATION AND APOA-I MUTATIONS ON RECEPTOR BINDING
J. Biol. Chem. 2000 275: 21262-21271. [Abstract] [Full Text] [PDF]  

Hiroaki Yagyu, Tetsuya Kitamine, Jun-ichi Osuga, Ryu-ichi Tozawa, Zhong Chen, Yuichi Kaji, Teruaki Oka, Stéphane Perrey, Yoshiaki Tamura, Ken Ohashi, Hiroaki Okazaki, Naoya Yahagi, Futoshi Shionoiri, Yoko Iizuka, Kenji Harada, Hitoshi Shimano, Hidetoshi Yamashita, Takanari Gotoda, Nobuhiro Yamada, and Shun Ishibashi

Absence of ACAT-1 Attenuates Atherosclerosis but Causes Dry Eye and Cutaneous Xanthomatosis in Mice with Congenital Hyperlipidemia
J. Biol. Chem. 2000 275: 21324-21330. [Abstract] [Full Text] [PDF]  

Samer El Bawab, Patrick Roddy, Ting Qian, Alicja Bielawska, John J. Lemasters, and Yusuf A. Hannun

Molecular Cloning and Characterization of a Human Mitochondrial Ceramidase
J. Biol. Chem. 2000 275: 21508-21513. [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Florencia B. Schapiro and Sergio Grinstein

Determinants of the pH of the Golgi Complex
J. Biol. Chem. 2000 275: 21025-21032. [Abstract] [Full Text] [PDF]  

Patrizia Fanara, Mary R. Hodel, Anita H. Corbett, and Alec E. Hodel

Quantitative Analysis of Nuclear Localization Signal (NLS)-Importin  Interaction through Fluorescence Depolarization. EVIDENCE FOR AUTO-INHIBITORY REGULATION OF NLS BINDING
J. Biol. Chem. 2000 275: 21218-21223. [Abstract] [Full Text] [PDF]  

Nicolas Vitale, Gustavo Pacheco-Rodriguez, Victor J. Ferrans, William Riemenschneider, Joel Moss, and Martha Vaughan

Specific Functional Interaction of Human Cytohesin-1 and ADP-ribosylation Factor Domain Protein (ARD1)
J. Biol. Chem. 2000 275: 21331-21339. [Abstract] [Full Text] [PDF]  

Rupert Abele, Kari Keinänen, and Dean R. Madden

Agonist-induced Isomerization in a Glutamate Receptor Ligand-binding Domain. A KINETIC AND MUTAGENETIC ANALYSIS
J. Biol. Chem. 2000 275: 21355-21363. [Abstract] [Full Text] [PDF]  

Darren Boehning and Suresh K. Joseph

Functional Properties of Recombinant Type I and Type III Inositol 1,4,5-Trisphosphate Receptor Isoforms Expressed in COS-7 Cells
J. Biol. Chem. 2000 275: 21492-21499. [Abstract] [Full Text] [PDF]  

Kwabena Opuni and John P. Reeves

Feedback Inhibition of Sodium/Calcium Exchange by Mitochondrial Calcium Accumulation
J. Biol. Chem. 2000 275: 21549-21554. [Abstract] [Full Text] [PDF]  

Zachary Spicer, Marian L. Miller, Anastasia Andringa, Tara M. Riddle, John J. Duffy, Thomas Doetschman, and Gary E. Shull

Stomachs of Mice Lacking the Gastric H,K-ATPase -Subunit Have Achlorhydria, Abnormal Parietal Cells, and Ciliated Metaplasia
J. Biol. Chem. 2000 275: 21555-21565. [Abstract] [Full Text] [PDF]  

Chalivendra C. Subbaiah and Martin M. Sachs

Maize cap1 Encodes a Novel SERCA-type Calcium-ATPase with a Calmodulin-binding Domain
J. Biol. Chem. 2000 275: 21678-21687. [Abstract] [Full Text] [PDF]  

Karlett J. Parra, Kelly L. Keenan, and Patricia M. Kane

The H Subunit (Vma13p) of the Yeast V-ATPase Inhibits the ATPase Activity of Cytosolic V₁ Complexes
J. Biol. Chem. 2000 275: 21761-21767. [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Laurent K. Verkoczy, Barbara-anne Guinn, and Neil L. Berinstein

Characterization of the Human B Cell RAG-associated Gene, hBRAG, as a B Cell Receptor Signal-enhancing Glycoprotein Dimer That Associates with Phosphorylated Proteins in Resting B Cells
J. Biol. Chem. 2000 275: 20967-20979. [Abstract] [Full Text] [PDF]  

Shu-Ping Zhong, Wei-Ya Ma, and Zigang Dong

ERKs and p38 Kinases Mediate Ultraviolet B-induced Phosphorylation of Histone H3 at Serine 10
J. Biol. Chem. 2000 275: 20980-20984. [Abstract] [Full Text] [PDF]  

Åke Sjöholm, Qimin Zhang, Nils Welsh, Anders Hansson, Olof Larsson, Michael Tally, and Per-Olof Berggren

Rapid Ca²⁺ Influx and Diacylglycerol Synthesis in Growth Hormone-mediated Islet -Cell Mitogenesis
J. Biol. Chem. 2000 275: 21033-21040. [Abstract] [Full Text] [PDF]  

Masaki Hosoya, Yuji Kawamata, Shoji Fukusumi, Ryo Fujii, Yugo Habata, Shuji Hinuma, Chieko Kitada, Susumu Honda, Tsutomu Kurokawa, Haruo Onda, Osamu Nishimura, and Masahiko Fujino

Molecular and Functional Characteristics of APJ. TISSUE DISTRIBUTION OF mRNA AND INTERACTION WITH THE ENDOGENOUS LIGAND APELIN
J. Biol. Chem. 2000 275: 21061-21067. [Abstract] [Full Text] [PDF]  

Gutian Xiao and Shao-Cong Sun

Negative Regulation of the Nuclear Factor B-inducing Kinase by a cis-Acting Domain
J. Biol. Chem. 2000 275: 21081-21085. [Abstract] [Full Text] [PDF]  

Richard Y. Liu, Chun Fan, Guoqing Liu, Nancy E. Olashaw, and Kenneth S. Zuckerman

Activation of p38 Mitogen-activated Protein Kinase Is Required for Tumor Necrosis Factor--supported Proliferation of Leukemia and Lymphoma Cell Lines
J. Biol. Chem. 2000 275: 21086-21093. [Abstract] [Full Text] [PDF]  

Roger D. Zühlke, Geoffrey S. Pitt, Richard W. Tsien, and Harald Reuter

Ca²⁺-sensitive Inactivation and Facilitation of L-type Ca²⁺ Channels Both Depend on Specific Amino Acid Residues in a Consensus Calmodulin-binding Motif in the_1C subunit
J. Biol. Chem. 2000 275: 21121-21129. [Abstract] [Full Text] [PDF]  

Jimmy Y. C. Chow, Jorge M. Uribe, and Kim E. Barrett

A Role for Protein Kinase C in the Inhibitory Effect of Epidermal Growth Factor on Calcium-stimulated Chloride Secretion in Human Colonic Epithelial Cells
J. Biol. Chem. 2000 275: 21169-21176. [Abstract] [Full Text] [PDF]  

James Hulit, Tal Bash, Maofu Fu, Ferruccio Galbiati, Chris Albanese, Daniel R. Sage, Amnon Schlegel, Jacob Zhurinsky, Michael Shtutman, Avri Ben-Ze'ev, Michael P. Lisanti, and Richard G. Pestell

The Cyclin D1 Gene Is Transcriptionally Repressed by Caveolin-1
J. Biol. Chem. 2000 275: 21203-21209. [Abstract] [Full Text] [PDF]  

Keiko Fukuyama, Michihiko Yoshida, Akio Yamashita, Tetsuya Deyama, Masaya Baba, Atsushi Suzuki, Hiroshi Mohri, Zenro Ikezawa, Hiroshi Nakajima, Syu-ichi Hirai, and Shigeo Ohno

MAPK Upstream Kinase (MUK)-binding Inhibitory Protein, a Negative Regulator of MUK/Dual Leucine Zipper-bearing Kinase/Leucine Zipper Protein Kinase
J. Biol. Chem. 2000 275: 21247-21254. [Abstract] [Full Text] [PDF]  

Jong Bae Park, Jung Hwan Kim, Yong Kim, Sang Hoon Ha, Jae Ho Kim, Jong-Shin Yoo, Guangwei Du, Michael A. Frohman, Pann-Ghill Suh, and Sung Ho Ryu

Cardiac Phospholipase D₂ Localizes to Sarcolemmal Membranes and Is Inhibited by -Actinin in an ADP-ribosylation Factor-reversible Manner
J. Biol. Chem. 2000 275: 21295-21301. [Abstract] [Full Text] [PDF]  

Nickolai O. Dulin, Phillip Pratt, Chinnaswamy Tiruppathi, Jiaxin Niu, Tatyana Voyno-Yasenetskaya, and Michael J. Dunn

Regulator of G Protein Signaling RGS3T Is Localized to the Nucleus and Induces Apoptosis
J. Biol. Chem. 2000 275: 21317-21323. [Abstract] [Full Text] [PDF]  

Xiangjun Zhou, Jian Liao, Anke Meyerdierks, Li Feng, Louie Naumovski, Erik C. Böttger, and M. Bishr Omary

Interferon- Induces Nmi-IFP35 Heterodimeric Complex Formation That Is Affected by the Phosphorylation of IFP35
J. Biol. Chem. 2000 275: 21364-21371. [Abstract] [Full Text] [PDF]  

Naomi Mukae, Hideki Yokoyama, Takakazu Yokokura, Yasuhiko Sakoyama, Hideki Sakahira, and Shigekazu Nagata

Identification and Developmental Expression of Inhibitor of Caspase-activated DNase (ICAD) in Drosophila melanogaster
J. Biol. Chem. 2000 275: 21402-21408. [Abstract] [Full Text] [PDF]  

Zerihun Assefa, Annelies Vantieghem, Marjan Garmyn, Wim Declercq, Peter Vandenabeele, Jackie R. Vandenheede, Roger Bouillon, Wilfried Merlevede, and Patrizia Agostinis

p38 Mitogen-activated Protein Kinase Regulates a Novel, Caspase-independent Pathway for the Mitochondrial Cytochrome c Release in Ultraviolet B Radiation-induced Apoptosis
J. Biol. Chem. 2000 275: 21416-21421. [Abstract] [Full Text] [PDF]  

Qi Zeng, Xiaoning Si, Heinrich Horstmann, Yue Xu, Wanjin Hong, and Catherine J. Pallen

Prenylation-dependent Association of Protein-tyrosine Phosphatases PRL-1, -2, and -3 with the Plasma Membrane and the Early Endosome
J. Biol. Chem. 2000 275: 21444-21452. [Abstract] [Full Text] [PDF]  

Yan Wu, Donald Dowbenko, Susan Spencer, Richard Laura, James Lee, Qimin Gu, and Laurence A. Lasky

Interaction of the Tumor Suppressor PTEN/MMAC with a PDZ Domain of MAGI3, a Novel Membrane-associated Guanylate Kinase
J. Biol. Chem. 2000 275: 21477-21485. [Abstract] [Full Text] [PDF]  

Yasuhito Abe, Suguru Matsumoto, Katsumi Kito, and Norifumi Ueda

Cloning and Expression of a Novel MAPKK-like Protein Kinase, Lymphokine-activated Killer T-cell-originated Protein Kinase, Specifically Expressed in the Testis and Activated Lymphoid Cells
J. Biol. Chem. 2000 275: 21525-21531. [Abstract] [Full Text] [PDF]  

Claudia M. van Tiel, Jan Westerman, Marten Paasman, Karel W. A. Wirtz, and Gerry T. Snoek

The Protein Kinase C-dependent Phosphorylation of Serine 166 Is Controlled by the Phospholipid Species Bound to the Phosphatidylinositol Transfer Protein
J. Biol. Chem. 2000 275: 21532-21538. [Abstract] [Full Text] [PDF]  

Alexander Gregorieff, Stéphane Pyronnet, Nahum Sonenberg, and André Veillette

Regulation of SOCS-1 Expression by Translational Repression
J. Biol. Chem. 2000 275: 21596-21604. [Abstract] [Full Text] [PDF]  

Amnon Schlegel and Michael P. Lisanti

A Molecular Dissection of Caveolin-1 Membrane Attachment and Oligomerization. TWO SEPARATE REGIONS OF THE CAVEOLIN-1 C-TERMINAL DOMAIN MEDIATE MEMBRANE BINDING AND OLIGOMER/OLIGOMER INTERACTIONS IN VIVO
J. Biol. Chem. 2000 275: 21605-21617. [Abstract] [Full Text] [PDF]  

Cecilia G. Unson, Cui-Rong Wu, Thomas P. Sakmar, and R. B. Merrifield

Selective Stabilization of the High Affinity Binding Conformation of Glucagon Receptor by the Long Splice Variant of G_s
J. Biol. Chem. 2000 275: 21631-21638. [Abstract] [Full Text] [PDF]  

Takeshi Yokoi, Masahide Ohmichi, Keiichi Tasaka, Akiko Kimura, Yuki Kanda, Jun Hayakawa, Masahiro Tahara, Koji Hisamoto, Hirohisa Kurachi, and Yuji Murata

Activation of the Luteinizing Hormone  Promoter by Gonadotropin-releasing Hormone Requires c-Jun NH₂-terminal Protein Kinase
J. Biol. Chem. 2000 275: 21639-21647. [Abstract] [Full Text] [PDF]  

Claudia Miele, Justin J. Rochford, Nathalie Filippa, Sophie Giorgetti-Peraldi, and Emmanuel Van Obberghen

Insulin and Insulin-like Growth Factor-I Induce Vascular Endothelial Growth Factor mRNA Expression via Different Signaling Pathways
J. Biol. Chem. 2000 275: 21695-21702. [Abstract] [Full Text] [PDF]  

Vincent Sauzeau, Hélène Le Jeune, Chrystelle Cario-Toumaniantz, Albert Smolenski, Suzanne M. Lohmann, Jacques Bertoglio, Pierre Chardin, Pierre Pacaud, and Gervaise Loirand

Cyclic GMP-dependent Protein Kinase Signaling Pathway Inhibits RhoA-induced Ca²⁺ Sensitization of Contraction in Vascular Smooth Muscle
J. Biol. Chem. 2000 275: 21722-21729. [Abstract] [Full Text] [PDF]  

Shigetomo Fukuhara, Maria Julia Marinissen, Mario Chiariello, and J. Silvio Gutkind

Signaling from G Protein-coupled Receptors to ERK5/Big MAPK 1 Involves G_q and G_12/13 Families of Heterotrimeric G Proteins. EVIDENCE FOR THE EXISTENCE OF A NOVEL Ras AND Rho-INDEPENDENT PATHWAY
J. Biol. Chem. 2000 275: 21730-21736. [Abstract] [Full Text] [PDF]  

Sheng-Jun Zhang, Heping Cheng, Ying-Ying Zhou, Ding-Ji Wang, Weizhong Zhu, Bruce Ziman, Harold Spurgoen, Robert J. Lefkowitz, Edward G. Lakatta, Walter J. Koch, and Rui-Ping Xiao

Inhibition of Spontaneous ₂-Adrenergic Activation Rescues ₁-Adrenergic Contractile Response in Cardiomyocytes Overexpressing ₂-Adrenoceptor
J. Biol. Chem. 2000 275: 21773-21779. [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Ryo Fujii, Masaki Hosoya, Shoji Fukusumi, Yuji Kawamata, Yugo Habata, Shuji Hinuma, Haruo Onda, Osamu Nishimura, and Masahiko Fujino

Identification of Neuromedin U as the Cognate Ligand of the Orphan G Protein-coupled Receptor FM-3
J. Biol. Chem. 2000 275: 21068-21074. [Abstract] [Full Text] [PDF]  

Dörthe M. Katschinski, Kristina Boos, Susann G. Schindler, and Joachim Fandrey

Pivotal Role of Reactive Oxygen Species as Intracellular Mediators of Hyperthermia-induced Apoptosis
J. Biol. Chem. 2000 275: 21094-21098. [Abstract] [Full Text] [PDF]  

Gunther Wennemuth, Ruth E. Westenbroek, Tao Xu, Bertil Hille, and Donner F. Babcock

Ca_V2.2 and Ca_V2.3 (N- and R-type) Ca²⁺ Channels in Depolarization-evoked Entry of Ca²⁺ into Mouse Sperm
J. Biol. Chem. 2000 275: 21210-21217. [Abstract] [Full Text] [PDF]  

Stephanie A. Orellana and Carmela Marfella-Scivittaro

Distinctive Cyclic AMP-dependent Protein Kinase Subunit Localization Is Associated with Cyst Formation and Loss of Tubulogenic Capacity in Madin-Darby Canine Kidney Cell Clones
J. Biol. Chem. 2000 275: 21233-21240. [Abstract] [Full Text] [PDF]  

Lizhen Yan and Michael E. Adams

The Spider Toxin -Aga IIIA Defines a High Affinity Site on Neuronal High Voltage-activated Calcium Channels
J. Biol. Chem. 2000 275: 21309-21316. [Abstract] [Full Text] [PDF]  

Christopher Westberg, Jian-Ping Yang, Hengli Tang, T. R. Reddy, and Flossie Wong-Staal

A Novel Shuttle Protein Binds to RNA Helicase A and Activates the Retroviral Constitutive Transport Element
J. Biol. Chem. 2000 275: 21396-21401. [Abstract] [Full Text] [PDF]  

Neta Ilan, Larry Cheung, Emese Pinter, and Joseph A. Madri

Platelet-Endothelial Cell Adhesion Molecule-1 (CD31), a Scaffolding Molecule for Selected Catenin Family Members Whose Binding Is Mediated by Different Tyrosine and Serine/Threonine Phosphorylation
J. Biol. Chem. 2000 275: 21435-21443. [Abstract] [Full Text] [PDF]  

Lil M. Pabón-Peña, Richard L. Goodwin, Linda J. Cise, and David Bader

Analysis of CMF1 Reveals a Bone Morphogenetic Protein-independent Component of the Cardiomyogenic Pathway
J. Biol. Chem. 2000 275: 21453-21459. [Abstract] [Full Text] [PDF]  

Kenji Okada, Tomoyuki Fujita, Kanji Minamoto, Hui Liao, Yoshifumi Naka, and David J. Pinsky

Potentiation of Endogenous Fibrinolysis and Rescue from Lung Ischemia/Reperfusion Injury in Interleukin (IL)-10-reconstituted IL-10 Null Mice
J. Biol. Chem. 2000 275: 21468-21476. [Abstract] [Full Text] [PDF]  

Hadar Feinberg, Shaun Park-Snyder, Anand R. Kolatkar, Charles T. Heise, Maureen E. Taylor, and William I. Weis

Structure of a C-type Carbohydrate Recognition Domain from the Macrophage Mannose Receptor
J. Biol. Chem. 2000 275: 21539-21548. [Abstract] [Full Text] [PDF]  

Judith López-Fernández, Daniela Palacios, Ana I. Castillo, Rosa M. Tolón, Ana Aranda, and Michael Karin

Differentiation of Lactotrope Precursor GHFT Cells in Response to Fibroblast Growth Factor-2
J. Biol. Chem. 2000 275: 21653-21660. [Abstract] [Full Text] [PDF]  

Hidenori Otera, Tomoyuki Harano, Masanori Honsho, Kamran Ghaedi, Satoru Mukai, Atsushi Tanaka, Atsushi Kawai, Nobuhiro Shimizu, and Yukio Fujiki

The Mammalian Peroxin Pex5pL, the Longer Isoform of the Mobile Peroxisome Targeting Signal (PTS) Type 1 Transporter, Translocates the Pex7p·PTS2 Protein Complex into Peroxisomes via Its Initial Docking Site, Pex14p
J. Biol. Chem. 2000 275: 21703-21714. [Abstract] [Full Text] [PDF]  

Tsuyoshi Matsumura, Hidenori Otera, and Yukio Fujiki

Disruption of the Interaction of the Longer Isoform of Pex5p, Pex5pL, with Pex7p Abolishes Peroxisome Targeting Signal Type 2 Protein Import in Mammals. STUDY WITH A NOVEL PEX5-IMPAIRED CHINESE HAMSTER OVARY CELL MUTANT
J. Biol. Chem. 2000 275: 21715-21721. [Abstract] [Full Text] [PDF]  

David B. Edelman, Robyn Meech, and Frederick S. Jones

The Homeodomain Protein Barx2 Contains Activator and Repressor Domains and Interacts with Members of the CREB Family
J. Biol. Chem. 2000 275: 21737-21745. [Abstract] [Full Text] [PDF]  

Thomas L. McCarthy, Changhua Ji, Yun Chen, Kenneth K. Kim, Masayoshi Imagawa, Yoshiaki Ito, and Michael Centrella

Runt Domain Factor (Runx)-dependent Effects on CCAAT/ Enhancer-binding Protein  Expression and Activity in Osteoblasts
J. Biol. Chem. 2000 275: 21746-21753. [Abstract] [Full Text] [PDF]  

Additions and Corrections:

María Gasset, José Laynez, Margarita Menéndez, Vincent Raussens, and Erik Goormaghtigh

Structural domain organization of gastric H⁺,K⁺-ATPase and its rearrangement during the catalytic cycle.
J. Biol. Chem. 2000 275: 21780. [Full Text] [PDF]  

Takeshi Murata, Kazuei Igarashi, Yoshimi Kakinuma, and Ichiro Yamato

Na⁺ binding of V-type Na⁺-ATPase in Enterococcus hirae.
J. Biol. Chem. 2000 275: 21780. [Full Text] [PDF]  

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