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Table of Contents: Jan 21 2000; 275 (3)   [Index by Author]       Other Issues:  
       Minireviews
       Accelerated Publications
       Carbohydrates, Lipids, and Other Natural Products
       Cell Biology and Metabolism
       Enzymology
       Membranes and Bioenergetics
       Nucleic Acids, Protein Synthesis, and Molecular Genetics
       Protein Chemistry and Structure
       Additions and Corrections
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Minireviews:

Timothy Browder, Judah Folkman, and Steven Pirie-Shepherd
The Hemostatic System as a Regulator of Angiogenesis
J. Biol. Chem. 2000 275: 1521-1524. [Full Text] [PDF]  


Accelerated Publications:

Jean-Noël Octave, Rachid Essalmani, Bernadette Tasiaux, Jean Menager, Christian Czech, and Luc Mercken
The Role of Presenilin-1 in the gamma -Secretase Cleavage of the Amyloid Precursor Protein of Alzheimer's Disease
J. Biol. Chem. 2000 275: 1525-1528. [Abstract] [Full Text] [PDF]  

Misty Moore, M. Stephen Harrison, Eric C. Peterson, and Ralph Henry
Chloroplast Oxa1p Homolog Albino3 Is Required for Post-translational Integration of the Light Harvesting Chlorophyll-binding Protein into Thylakoid Membranes
J. Biol. Chem. 2000 275: 1529-1532. [Abstract] [Full Text] [PDF]  


Carbohydrates, Lipids, and Other Natural Products:

Shean-Tai Chiou, Yih-Wen Chen, Sang-Ching Chen, Chih-Fang Chao, and Teh-Yung Liu
Isolation and Characterization of Proteins That Bind to Galactose, Lipopolysaccharide of Escherichia coli, and Protein A of Staphylococcus aureus from the Hemolymph of Tachypleus tridentatus
J. Biol. Chem. 2000 275: 1630-1634. [Abstract] [Full Text] [PDF]  


Cell Biology and Metabolism:

Koichiro Tsuchiya, Masanori Yoshizumi, Hitoshi Houchi, and Ronald P. Mason
Nitric Oxide-forming Reaction between the Iron-N-Methyl-D-glucamine Dithiocarbamate Complex and Nitrite
J. Biol. Chem. 2000 275: 1551-1556. [Abstract] [Full Text] [PDF]  

Liliana Busconi, Jiazhen Guan, and Bradley M. Denker
Degradation of Heterotrimeric Galpha o Subunits via the Proteosome Pathway Is Induced by the hsp90-specific Compound Geldanamycin
J. Biol. Chem. 2000 275: 1565-1569. [Abstract] [Full Text] [PDF]  

Peter van Kerkhof, Roland Govers, Cristina M. Alves dos Santos, and Ger J. Strous
Endocytosis and Degradation of the Growth Hormone Receptor Are Proteasome-dependent
J. Biol. Chem. 2000 275: 1575-1580. [Abstract] [Full Text] [PDF]  

Suling Li, Kajsa M. Paulsson, Shangwu Chen, Hans-Olov Sjögren, and Ping Wang
Tapasin Is Required for Efficient Peptide Binding to Transporter Associated with Antigen Processing
J. Biol. Chem. 2000 275: 1581-1586. [Abstract] [Full Text] [PDF]  

Magalie A. Ravier, Kazuhiro Eto, Françoise C. Jonkers, Myriam Nenquin, Takashi Kadowaki, and Jean-Claude Henquin
The Oscillatory Behavior of Pancreatic Islets from Mice with Mitochondrial Glycerol-3-phosphate Dehydrogenase Knockout
J. Biol. Chem. 2000 275: 1587-1593. [Abstract] [Full Text] [PDF]  

Gergely L. Lukacs, Peter Haggie, Olivier Seksek, D. Lechardeur, Neal Freedman, and A. S. Verkman
Size-dependent DNA Mobility in Cytoplasm and Nucleus
J. Biol. Chem. 2000 275: 1625-1629. [Abstract] [Full Text] [PDF]  

Anna Baoutina, Roger T. Dean, and Wendy Jessup
Macrophages Can Decrease the Level of Cholesteryl Ester Hydroperoxides in Low Density Lipoprotein
J. Biol. Chem. 2000 275: 1635-1644. [Abstract] [Full Text] [PDF]  

Marco A. Gárate and Marco T. Núñez
Overexpression of the Ferritin Iron-responsive Element Decreases the Labile Iron Pool and Abolishes the Regulation of Iron Absorption by Intestinal Epithelial (Caco-2) Cells
J. Biol. Chem. 2000 275: 1651-1655. [Abstract] [Full Text] [PDF]  

Thierry Christophe, Marie-Josèphe Rabiet, Marianne Tardif, Marie-Danielle Milcent, and François Boulay
Human Complement 5a (C5a) Anaphylatoxin Receptor (CD88) Phosphorylation Sites and Their Specific Role in Receptor Phosphorylation and Attenuation of G Protein-mediated Responses. DESENSITIZATION OF C5a RECEPTOR CONTROLS SUPEROXIDE PRODUCTION BUT NOT RECEPTOR SEQUESTRATION IN HL-60 CELLS
J. Biol. Chem. 2000 275: 1656-1664. [Abstract] [Full Text] [PDF]  

Yee-Sook Cho, Myung-Kwan Han, Young Bong Choi, Yungdae Yun, Jaekyoon Shin, and Uh-Hyun Kim
Direct Interaction of the CD38 Cytoplasmic Tail and the Lck SH2 Domain. CD38 TRANSDUCES T CELL ACTIVATION SIGNALS THROUGH ASSOCIATED Lck
J. Biol. Chem. 2000 275: 1685-1690. [Abstract] [Full Text] [PDF]  

Ning Guo, Douglas V. Faller, and Cyrus Vaziri
A Novel DNA Damage Checkpoint Involving Post-transcriptional Regulation of Cyclin A Expression
J. Biol. Chem. 2000 275: 1715-1722. [Abstract] [Full Text] [PDF]  

Jun-ichi Abe, Masanori Okuda, Qunhua Huang, Masanori Yoshizumi, and Bradford C. Berk
Reactive Oxygen Species Activate p90 Ribosomal S6 Kinase via Fyn and Ras
J. Biol. Chem. 2000 275: 1739-1748. [Abstract] [Full Text] [PDF]  

Irene M. L. W. Keularts, Roosje M. A. van Gorp, Marion A. H. Feijge, Wim M. J. Vuist, and Johan W. M. Heemskerk
alpha 2A-Adrenergic Receptor Stimulation Potentiates Calcium Release in Platelets by Modulating cAMP Levels
J. Biol. Chem. 2000 275: 1763-1772. [Abstract] [Full Text] [PDF]  

Alison D. Short and Colin W. Taylor
Parathyroid Hormone Controls the Size of the Intracellular Ca2+ Stores Available to Receptors Linked to Inositol Trisphosphate Formation
J. Biol. Chem. 2000 275: 1807-1813. [Abstract] [Full Text] [PDF]  

Lilly Y. W. Bourguignon, Hongbo Zhu, Lijun Shao, and You Wei Chen
CD44 Interaction with Tiam1 Promotes Rac1 Signaling and Hyaluronic Acid-mediated Breast Tumor Cell Migration
J. Biol. Chem. 2000 275: 1829-1838. [Abstract] [Full Text] [PDF]  

Aiyang Cheng, Nicholas M. Dean, and Richard E. Honkanen
Serine/Threonine Protein Phosphatase Type 1gamma 1 Is Required for the Completion of Cytokinesis in Human A549 Lung Carcinoma Cells
J. Biol. Chem. 2000 275: 1846-1854. [Abstract] [Full Text] [PDF]  

Harold M. Wright, Clary B. Clish, Toshiyuki Mikami, Stefanie Hauser, Kazunori Yanagi, Ryuji Hiramatsu, Charles N. Serhan, and Bruce M. Spiegelman
A Synthetic Antagonist for the Peroxisome Proliferator-activated Receptor gamma  Inhibits Adipocyte Differentiation
J. Biol. Chem. 2000 275: 1873-1877. [Abstract] [Full Text] [PDF]  

Frank Thévenod, Jenny M. Friedmann, Alice D. Katsen, and Ingeborg A. Hauser
Up-regulation of Multidrug Resistance P-glycoprotein via Nuclear Factor-kappa B Activation Protects Kidney Proximal Tubule Cells from Cadmium- and Reactive Oxygen Species-induced Apoptosis
J. Biol. Chem. 2000 275: 1887-1896. [Abstract] [Full Text] [PDF]  

Stephan Witte, Martin Villalba, Kun Bi, Yuhong Liu, Noah Isakov, and Amnon Altman
Inhibition of the c-Jun N-terminal Kinase/AP-1 and NF-kappa B Pathways by PICOT, a Novel Protein Kinase C-interacting Protein with a Thioredoxin Homology Domain
J. Biol. Chem. 2000 275: 1902-1909. [Abstract] [Full Text] [PDF]  

Alexandre Mezghrani, Joel Courageot, Jean Claude Mani, Martine Pugniere, Paul Bastiani, and Raymond Miquelis
Protein-disulfide Isomerase (PDI) in FRTL5 Cells. pH-DEPENDENT THYROGLOBULIN/PDI INTERACTIONS DETERMINE A NOVEL PDI FUNCTION IN THE POST-ENDOPLASMIC RETICULUM OF THYROCYTES
J. Biol. Chem. 2000 275: 1920-1929. [Abstract] [Full Text] [PDF]  

Mette Dahl Andersen, Peter Kamp Busk, Ib Svendsen, and Birger Lindberg Møller
Cytochromes P-450 from Cassava (Manihot esculenta Crantz) Catalyzing the First Steps in the Biosynthesis of the Cyanogenic Glucosides Linamarin and Lotaustralin. CLONING, FUNCTIONAL EXPRESSION IN PICHIA PASTORIS, AND SUBSTRATE SPECIFICITY OF THE ISOLATED RECOMBINANT ENZYMES
J. Biol. Chem. 2000 275: 1966-1975. [Abstract] [Full Text] [PDF]  

Nancy Y. Marcus and David H. Perlmutter
Glucosidase and Mannosidase Inhibitors Mediate Increased Secretion of Mutant alpha 1 Antitrypsin Z
J. Biol. Chem. 2000 275: 1987-1992. [Abstract] [Full Text] [PDF]  

Cydney C. Brooks, Philipp E. Scherer, Kelly Cleveland, Jennifer L. Whittemore, Harvey F. Lodish, and Bentley Cheatham
Pantophysin Is a Phosphoprotein Component of Adipocyte Transport Vesicles and Associates with GLUT4-containing Vesicles
J. Biol. Chem. 2000 275: 2029-2036. [Abstract] [Full Text] [PDF]  

Matthew D. Potter and Christopher V. Nicchitta
Ribosome-independent Regulation of Translocon Composition and Sec61alpha Conformation
J. Biol. Chem. 2000 275: 2037-2045. [Abstract] [Full Text] [PDF]  

Christian Sirard, Sammy Kim, Christine Mirtsos, Paul Tadich, Pamela A. Hoodless, Annick Itié, Robert Maxson, Jeffrey L. Wrana, and Tak W. Mak
Targeted Disruption in Murine Cells Reveals Variable Requirement for Smad4 in Transforming Growth Factor beta -related Signaling
J. Biol. Chem. 2000 275: 2063-2070. [Abstract] [Full Text] [PDF]  

Charlene McWhinney, Dean Wenham, Sujata Kanwal, Vivian Kalman, Carl Hansen, and Janet D. Robishaw
Constitutively Active Mutants of the alpha 1a- and the alpha 1b-Adrenergic Receptor Subtypes Reveal Coupling to Different Signaling Pathways and Physiological Responses in Rat Cardiac Myocytes
J. Biol. Chem. 2000 275: 2087-2097. [Abstract] [Full Text] [PDF]  

Hiroshi Ueda, Hiroshi Itoh, Junji Yamauchi, Rika Morishita, Yoshito Kaziro, Kanefusa Kato, and Tomiko Asano
G Protein beta gamma Subunits Induce Stress Fiber Formation and Focal Adhesion Assembly in a Rho-dependent Manner in HeLa Cells
J. Biol. Chem. 2000 275: 2098-2102. [Abstract] [Full Text] [PDF]  

Tao Zhu and Peter E. Lobie
Janus Kinase 2-dependent Activation of p38 Mitogen-activated Protein Kinase by Growth Hormone. RESULTANT TRANSCRIPTIONAL ACTIVATION OF ATF-2 AND CHOP, CYTOSKELETAL RE-ORGANIZATION AND MITOGENESIS
J. Biol. Chem. 2000 275: 2103-2114. [Abstract] [Full Text] [PDF]  

Yvonne Y. Wu and Ralph A. Bradshaw
Activation of the Stat3 Signaling Pathway Is Required for Differentiation by Interleukin-6 in PC12-E2 Cells
J. Biol. Chem. 2000 275: 2147-2156. [Abstract] [Full Text] [PDF]  

Jingzhen Yuan, Lee Slice, John H. Walsh, and Enrique Rozengurt
Activation of Protein Kinase D by Signaling through the alpha  Subunit of the Heterotrimeric G Protein Gq
J. Biol. Chem. 2000 275: 2157-2164. [Abstract] [Full Text] [PDF]  

Michelle R. Kuhne, Gregory Ku, and Arthur Weiss
A Guanine Nucleotide Exchange Factor-independent Function of Vav1 in Transcriptional Activation
J. Biol. Chem. 2000 275: 2185-2190. [Abstract] [Full Text] [PDF]  

Benjamin Seo, Eric W. Choy, Stuart Maudsley, William E. Miller, Brenda A. Wilson, and Louis M. Luttrell
Pasteurella multocida Toxin Stimulates Mitogen-activated Protein Kinase via Gq/11-dependent Transactivation of the Epidermal Growth Factor Receptor
J. Biol. Chem. 2000 275: 2239-2245. [Abstract] [Full Text] [PDF]  


Enzymology:

Ola Hammarsten, Lisa G. DeFazio, and Gilbert Chu
Activation of DNA-dependent Protein Kinase by Single-stranded DNA Ends
J. Biol. Chem. 2000 275: 1541-1550. [Abstract] [Full Text] [PDF]  

Thomas Brüser, Thorsten Selmer, and Christiane Dahl
"ADP Sulfurylase" from Thiobacillus denitrificans Is an Adenylylsulfate:Phosphate Adenylyltransferase and Belongs to a New Family of Nucleotidyltransferases
J. Biol. Chem. 2000 275: 1691-1698. [Abstract] [Full Text] [PDF]  

Jean-Michel Jault, Sonia Fieulaine, Sylvie Nessler, Philippe Gonzalo, Attilio Di Pietro, Josef Deutscher, and Anne Galinier
The HPr Kinase from Bacillus subtilis Is a Homo-oligomeric Enzyme Which Exhibits Strong Positive Cooperativity for Nucleotide and Fructose 1,6-Bisphosphate Binding
J. Biol. Chem. 2000 275: 1773-1780. [Abstract] [Full Text] [PDF]  

Claus C. Fuglsang, Randy M. Berka, Jill A. Wahleithner, Sakari Kauppinen, Jeffrey R. Shuster, Grethe Rasmussen, Torben Halkier, Henrik Dalbøge, and Bernard Henrissat
Biochemical Analysis of Recombinant Fungal Mutanases. A NEW FAMILY OF alpha 1,3-GLUCANASES WITH NOVEL CARBOHYDRATE-BINDING DOMAINS
J. Biol. Chem. 2000 275: 2009-2018. [Abstract] [Full Text] [PDF]  

Ingram Iaccarino, Giancarlo Marra, Patrick Dufner, and Josef Jiricny
Mutation in the Magnesium Binding Site of hMSH6 Disables the hMutSalpha Sliding Clamp from Translocating along DNA
J. Biol. Chem. 2000 275: 2080-2086. [Abstract] [Full Text] [PDF]  

Stephen C. Bunnell, Maximilian Diehn, Michael B. Yaffe, Paul R. Findell, Lewis C. Cantley, and Leslie J. Berg
Biochemical Interactions Integrating Itk with the T Cell Receptor-initiated Signaling Cascade
J. Biol. Chem. 2000 275: 2219-2230. [Abstract] [Full Text] [PDF]  


Membranes and Bioenergetics:

Ashish Arora, Dennis Rinehart, Gabor Szabo, and Lukas K. Tamm
Refolded Outer Membrane Protein A of Escherichia coli Forms Ion Channels with Two Conductance States in Planar Lipid Bilayers
J. Biol. Chem. 2000 275: 1594-1600. [Abstract] [Full Text] [PDF]  

Nianhang Chen, Jasmine V. Ferrer, Jonathan A. Javitch, and Joseph B. Justice, Jr.
Transport-dependent Accessibility of a Cytoplasmic Loop Cysteine in the Human Dopamine Transporter
J. Biol. Chem. 2000 275: 1608-1614. [Abstract] [Full Text] [PDF]  

Malliga E. Ganapathy, Wei Huang, D. Prasanna Rajan, A. Lee Carter, Mitsuru Sugawara, Ken Iseki, Frederick H. Leibach, and Vadivel Ganapathy
beta -Lactam Antibiotics as Substrates for OCTN2, an Organic Cation/Carnitine Transporter
J. Biol. Chem. 2000 275: 1699-1707. [Abstract] [Full Text] [PDF]  

Hongye Sun and Thomas C. Squier
Ordered and Cooperative Binding of Opposing Globular Domains of Calmodulin to the Plasma Membrane Ca-ATPase
J. Biol. Chem. 2000 275: 1731-1738. [Abstract] [Full Text] [PDF]  

Martin Mense, Lisa A. Dunbar, Rhoda Blostein, and Michael J. Caplan
Residues of the Fourth Transmembrane Segments of the Na,K-ATPase and the Gastric H,K-ATPase Contribute to Cation Selectivity
J. Biol. Chem. 2000 275: 1749-1756. [Abstract] [Full Text] [PDF]  

Sanghwa Han, Satoshi Takahashi, and Denis L. Rousseau
Time Dependence of the Catalytic Intermediates in Cytochrome c Oxidase
J. Biol. Chem. 2000 275: 1910-1919. [Abstract] [Full Text] [PDF]  

Gilles Crambert, Udo Hasler, Ahmed T. Beggah, Chuliang Yu, Nikolai N. Modyanov, Jean-Daniel Horisberger, Lionel Lelièvre, and Käthi Geering
Transport and Pharmacological Properties of Nine Different Human Na,K-ATPase Isozymes
J. Biol. Chem. 2000 275: 1976-1986. [Abstract] [Full Text] [PDF]  

Alla Shainskaya, Anne Schneeberger, Hans-Jürgen Apell, and Steven J. D. Karlish
Entrance Port for Na+ and K+ Ions on Na+,K+-ATPase in the Cytoplasmic Loop between Trans-membrane Segments M6 and M7 of the alpha  Subunit. PROXIMITY OF THE CYTOPLASMIC SEGMENT OF THE beta  SUBUNIT
J. Biol. Chem. 2000 275: 2019-2028. [Abstract] [Full Text] [PDF]  

Serge Moffett, Deborah A. Brown, and Maurine E. Linder
Lipid-dependent Targeting of G Proteins into Rafts
J. Biol. Chem. 2000 275: 2191-2198. [Abstract] [Full Text] [PDF]  


Nucleic Acids, Protein Synthesis, and Molecular Genetics:

Tina M. Wilson, Alice D. Chen, and Tao-shih Hsieh
Cloning and Characterization of Drosophila Topoisomerase IIIbeta . RELAXATION OF HYPERNEGATIVELY SUPERCOILED DNA
J. Biol. Chem. 2000 275: 1533-1540. [Abstract] [Full Text] [PDF]  

Tatiana Efimova and Richard L. Eckert
Regulation of Human Involucrin Promoter Activity by Novel Protein Kinase C Isoforms
J. Biol. Chem. 2000 275: 1601-1607. [Abstract] [Full Text] [PDF]  

Qingquan Liu, Won-chae Choe, and Judith L. Campbell
Identification of the Xenopus laevis Homolog of Saccharomyces cerevisiae DNA2 and Its Role in DNA Replication
J. Biol. Chem. 2000 275: 1615-1624. [Abstract] [Full Text] [PDF]  

Karin Müller and Nicolas Mermod
The Histone-interacting Domain of Nuclear Factor I Activates Simian Virus 40 DNA Replication in Vivo
J. Biol. Chem. 2000 275: 1645-1650. [Abstract] [Full Text] [PDF]  

Dongsheng Ping, Gunther Boekhoudt, Fuping Zhang, Ann Morris, Sjaak Philipsen, Stephen T. Warren, and Jeremy M. Boss
Sp1 Binding Is Critical for Promoter Assembly and Activation of the MCP-1 Gene by Tumor Necrosis Factor
J. Biol. Chem. 2000 275: 1708-1714. [Abstract] [Full Text] [PDF]  

Hyung-in Choi, Jung-hee Hong, Jin-ok Ha, Jung-youn Kang, and Soo Young Kim
ABFs, a Family of ABA-responsive Element Binding Factors
J. Biol. Chem. 2000 275: 1723-1730. [Abstract] [Full Text] [PDF]  

Victoria Drewett, Silke Muller, Jane Goodall, and Peter E. Shaw
Dimer Formation by Ternary Complex Factor ELK-1
J. Biol. Chem. 2000 275: 1757-1762. [Abstract] [Full Text] [PDF]  

Vasanthi Ramachandiran, Charles Willms, Gisela Kramer, and Boyd Hardesty
Fluorophores at the N Terminus of Nascent Chloramphenicol Acetyltransferase Peptides Affect Translation and Movement through the Ribosome
J. Biol. Chem. 2000 275: 1781-1786. [Abstract] [Full Text] [PDF]  

Corinna Oberste-Berghaus, Kerstin Zanger, Koshi Hashimoto, Ronald N. Cohen, Anthony N. Hollenberg, and Fredric E. Wondisford
Thyroid Hormone-independent Interaction between the Thyroid Hormone Receptor beta 2 Amino Terminus and Coactivators
J. Biol. Chem. 2000 275: 1787-1792. [Abstract] [Full Text] [PDF]  

Ralf Schwanbeck, Guidalberto Manfioletti, and Jacek R. Wisniewski
Architecture of High Mobility Group Protein I-C·DNA Complex and Its Perturbation upon Phosphorylation by Cdc2 Kinase
J. Biol. Chem. 2000 275: 1793-1801. [Abstract] [Full Text] [PDF]  

Madasamy Shanmugavelu, Apollo R. Baytan, Jonathan D. Chesnut, and Bryony C. Bonning
A Novel Protein That Binds Juvenile Hormone Esterase in Fat Body Tissue and Pericardial Cells of the Tobacco Hornworm Manduca sexta L.
J. Biol. Chem. 2000 275: 1802-1806. [Abstract] [Full Text] [PDF]  

Yang Xia, Jeanie B. McMillin, Amy Lewis, Meredith Moore, Wei G. Zhu, R. Sanders Williams, and Rodney E. Kellems
Electrical Stimulation of Neonatal Cardiac Myocytes Activates the NFAT3 and GATA4 Pathways and Up-regulates the Adenylosuccinate Synthetase 1 Gene
J. Biol. Chem. 2000 275: 1855-1863. [Abstract] [Full Text] [PDF]  

Milo B. Fasken, Robert Saunders, Martin Rosenberg, and David W. Brighty
A Leptomycin B-sensitive Homologue of Human CRM1 Promotes Nuclear Export of Nuclear Export Sequence-containing Proteins in Drosophila Cells
J. Biol. Chem. 2000 275: 1878-1886. [Abstract] [Full Text] [PDF]  

Jeffrey D. Croissant, Stacey Carpenter, and David Bader
Identification and Genomic Cloning of CMHC1. A UNIQUE MYOSIN HEAVY CHAIN EXPRESSED EXCLUSIVELY IN THE DEVELOPING CHICKEN HEART
J. Biol. Chem. 2000 275: 1944-1951. [Abstract] [Full Text] [PDF]  

Buyung Santoso, Benjamin D. Ortiz, and Astar Winoto
Control of Organ-specific Demethylation by an Element of the T-cell Receptor-alpha Locus Control Region
J. Biol. Chem. 2000 275: 1952-1958. [Abstract] [Full Text] [PDF]  

Mariko Murata and Shosuke Kawanishi
Oxidative DNA Damage by Vitamin A and Its Derivative via Superoxide Generation
J. Biol. Chem. 2000 275: 2003-2008. [Abstract] [Full Text] [PDF]  

Christian Bergsdorf, Krzysztof Paliga, Sylvia Kreger, Colin L. Masters, and Konrad Beyreuther
Identification of cis-Elements Regulating Exon 15 Splicing of the Amyloid Precursor Protein Pre-mRNA
J. Biol. Chem. 2000 275: 2046-2056. [Abstract] [Full Text] [PDF]  

Yong-Sik Kim, Sung-Jun Han, Ji-Hwan Ryu, Kun-Ho Choi, Young-Suk Hong, Yong-Hoon Chung, Sylvie Perrot, Anna Raibaud, Paul T. Brey, and Won-Jae Lee
Lipopolysaccharide-activated Kinase, an Essential Component for the Induction of the Antimicrobial Peptide Genes in Drosophila melanogaster Cells
J. Biol. Chem. 2000 275: 2071-2079. [Abstract] [Full Text] [PDF]  

Miguel A. Rodríguez-Gabriel, Miguel Remacha, and Juan P. G. Ballesta
The RNA Interacting Domain but Not the Protein Interacting Domain Is Highly Conserved in Ribosomal Protein P0
J. Biol. Chem. 2000 275: 2130-2136. [Abstract] [Full Text] [PDF]  

Lars H. Jensen, Karin C. Nitiss, Angela Rose, Jiaowang Dong, Junfang Zhou, Tao Hu, Neil Osheroff, Peter B. Jensen, Maxwell Sehested, and John L. Nitiss
A Novel Mechanism of Cell Killing by Anti-topoisomerase II Bisdioxopiperazines
J. Biol. Chem. 2000 275: 2137-2146. [Abstract] [Full Text] [PDF]  

Ravi R. Iyer, Anna Pluciennik, William A. Rosche, Richard R. Sinden, and Robert D. Wells
DNA Polymerase III Proofreading Mutants Enhance the Expansion and Deletion of Triplet Repeat Sequences in Escherichia coli
J. Biol. Chem. 2000 275: 2174-2184. [Abstract] [Full Text] [PDF]  

Eitan Glick, Dena Leshkowitz, and Michael D. Walker
Transcription Factor BETA2 Acts Cooperatively with E2A and PDX1 to Activate the Insulin Gene Promoter
J. Biol. Chem. 2000 275: 2199-2204. [Abstract] [Full Text] [PDF]  

Julie K. Horton, Rajendra Prasad, Esther Hou, and Samuel H. Wilson
Protection against Methylation-induced Cytotoxicity by DNA Polymerase beta -Dependent Long Patch Base Excision Repair
J. Biol. Chem. 2000 275: 2211-2218. [Abstract] [Full Text] [PDF]  

Pnina Weisman-Shomer, Yael Naot, and Michael Fry
Tetrahelical Forms of the Fragile X Syndrome Expanded Sequence d(CGG)n Are Destabilized by Two Heterogeneous Nuclear Ribonucleoprotein-related Telomeric DNA-binding Proteins
J. Biol. Chem. 2000 275: 2231-2238. [Abstract] [Full Text] [PDF]  


Protein Chemistry and Structure:

Uwe Bertsch, Christina Deschermeier, Werner Fanick, Irute Girkontaite, Kirsten Hillemeier, Heiko Johnen, Wolfgang Weglöhner, Frank Emmrich, and Georg W. Mayr
The Second Messenger Binding Site of Inositol 1,4,5-Trisphosphate 3-Kinase Is Centered in the Catalytic Domain and Related to the Inositol Trisphosphate Receptor Site
J. Biol. Chem. 2000 275: 1557-1564. [Abstract] [Full Text] [PDF]  

Yong-sung Kim, Jonathan S. Wall, Jeffrey Meyer, Charles Murphy, Theodore W. Randolph, Mark C. Manning, Alan Solomon, and John F. Carpenter
Thermodynamic Modulation of Light Chain Amyloid Fibril Formation
J. Biol. Chem. 2000 275: 1570-1574. [Abstract] [Full Text] [PDF]  

Anders Cavallin, Helena Arozenius, Karin Kristensson, Per Antonsson, Daniel E. Otzen, Per Björk, and Göran Forsberg
The Spectral and Thermodynamic Properties of Staphylococcal Enterotoxin A, E, and Variants Suggest That Structural Modifications Are Important to Control Their Function
J. Biol. Chem. 2000 275: 1665-1672. [Abstract] [Full Text] [PDF]  

Pascal Kuner, Bernd Bohrmann, Lars O. Tjernberg, Jan Näslund, Gerda Huber, Suna Celenk, Fiona Grüninger-Leitch, J. Grayson Richards, Roland Jakob-Roetne, John A. Kemp, and Christer Nordstedt
Controlling Polymerization of beta -Amyloid and Prion-derived Peptides with Synthetic Small Molecule Ligands
J. Biol. Chem. 2000 275: 1673-1678. [Abstract] [Full Text] [PDF]  

Syun-Ru Yeh, Manon Couture, Yannick Ouellet, Michel Guertin, and Denis L. Rousseau
A Cooperative Oxygen Binding Hemoglobin from Mycobacterium tuberculosis. STABILIZATION OF HEME LIGANDS BY A DISTAL TYROSINE RESIDUE
J. Biol. Chem. 2000 275: 1679-1684. [Abstract] [Full Text] [PDF]  

Michael T. W. Liu, Margot M. Wuebbens, K. V. Rajagopalan, and Hermann Schindelin
Crystal Structure of the Gephyrin-related Molybdenum Cofactor Biosynthesis Protein MogA from Escherichia coli
J. Biol. Chem. 2000 275: 1814-1822. [Abstract] [Full Text] [PDF]  

Sandrine Braud, Marina A. A. Parry, Rachid Maroun, Cassian Bon, and Anne Wisner
The Contribution of Residues 192 and 193 to the Specificity of Snake Venom Serine Proteinases
J. Biol. Chem. 2000 275: 1823-1828. [Abstract] [Full Text] [PDF]  

Wei Shu, Hong Ji, and Min Lu
Interactions between HIV-1 gp41 Core and Detergents and Their Implications for Membrane Fusion
J. Biol. Chem. 2000 275: 1839-1845. [Abstract] [Full Text] [PDF]  

Lothar Gremer, Sabine Kellner, Holger Dobbek, Robert Huber, and Ortwin Meyer
Binding of Flavin Adenine Dinucleotide to Molybdenum-containing Carbon Monoxide Dehydrogenase from Oligotropha carboxidovorans. STRUCTURAL AND FUNCTIONAL ANALYSIS OF A CARBON MONOXIDE DEHYDROGENASE SPECIES IN WHICH THE NATIVE FLAVOPROTEIN HAS BEEN REPLACED BY ITS RECOMBINANT COUNTERPART PRODUCED IN ESCHERICHIA COLI
J. Biol. Chem. 2000 275: 1864-1872. [Abstract] [Full Text] [PDF]  

Chao-Lin Liu, Chia-Chu Tsai, Su-Chang Lin, Li-In Wang, Chong-Ing Hsu, Ming-Jing Hwang, and Jung-Yaw Lin
Primary Structure and Function Analysis of the Abrus precatorius Agglutinin A Chain by Site-directed Mutagenesis. Pro199 OF AMPHIPHILIC alpha -HELIX H IMPAIRS PROTEIN SYNTHESIS INHIBITORY ACTIVITY
J. Biol. Chem. 2000 275: 1897-1901. [Abstract] [Full Text] [PDF]  

Ethan P. Marin, A. Gopala Krishna, Tatyana A. Zvyaga, Juergen Isele, Friedrich Siebert, and Thomas P. Sakmar
The Amino Terminus of the Fourth Cytoplasmic Loop of Rhodopsin Modulates Rhodopsin-Transducin Interaction
J. Biol. Chem. 2000 275: 1930-1936. [Abstract] [Full Text] [PDF]  

Oliver P. Ernst, Christoph K. Meyer, Ethan P. Marin, Peter Henklein, Wing-Yee Fu, Thomas P. Sakmar, and Klaus Peter Hofmann
Mutation of the Fourth Cytoplasmic Loop of Rhodopsin Affects Binding of Transducin and Peptides Derived from the Carboxyl-terminal Sequences of Transducin alpha  and gamma  Subunits
J. Biol. Chem. 2000 275: 1937-1943. [Abstract] [Full Text] [PDF]  

D. Brian Foster, Li-Hua Shen, John Kelly, Pierre Thibault, Jennifer E. Van Eyk, and Alan S. Mak
Phosphorylation of Caldesmon by p21-activated Kinase. IMPLICATIONS FOR THE Ca2+ SENSITIVITY OF SMOOTH MUSCLE CONTRACTION
J. Biol. Chem. 2000 275: 1959-1965. [Abstract] [Full Text] [PDF]  

Niels Behrendt, Ole N. Jensen, Lars H. Engelholm, Ejvind Mørtz, Matthias Mann, and Keld Danø
A Urokinase Receptor-associated Protein with Specific Collagen Binding Properties
J. Biol. Chem. 2000 275: 1993-2002. [Abstract] [Full Text] [PDF]  

Katarzyna Koziak, Elzbieta Kaczmarek, Agnes Kittel, Jean Sévigny, Jan Krzysztof Blusztajn, Jan Schulte am Esch, II, Masato Imai, Olaf Guckelberger, Christian Goepfert, Imrana Qawi, and Simon C. Robson
Palmitoylation Targets CD39/Endothelial ATP Diphosphohydrolase to Caveolae
J. Biol. Chem. 2000 275: 2057-2062. [Abstract] [Full Text] [PDF]  

Mark P. de Caestecker, Tetsuro Yahata, David Wang, W. Tony Parks, Shixia Huang, Caroline S. Hill, Toshi Shioda, Anita B. Roberts, and Robert J. Lechleider
The Smad4 Activation Domain (SAD) Is a Proline-rich, p300-dependent Transcriptional Activation Domain
J. Biol. Chem. 2000 275: 2115-2122. [Abstract] [Full Text] [PDF]  

Anthony J. Reardon, Magali Le Goff, Michael D. Briggs, David McLeod, John K. Sheehan, David J. Thornton, and Paul N. Bishop
Identification in Vitreous and Molecular Cloning of Opticin, a Novel Member of the Family of Leucine-rich Repeat Proteins of the Extracellular Matrix
J. Biol. Chem. 2000 275: 2123-2129. [Abstract] [Full Text] [PDF]  

Aaron K. Sato, Jennifer A. Zarutskie, Mia M. Rushe, Aleksey Lomakin, Sateesh K. Natarajan, Scheherazade Sadegh-Nasseri, George B. Benedek, and Lawrence J. Stern
Determinants of the Peptide-induced Conformational Change in the Human Class II Major Histocompatibility Complex Protein HLA-DR1
J. Biol. Chem. 2000 275: 2165-2173. [Abstract] [Full Text] [PDF]  

Dieter P. Reinhardt, Jay E. Gambee, Robert N. Ono, Hans Peter Bächinger, and Lynn Y. Sakai
Initial Steps in Assembly of Microfibrils. FORMATION OF DISULFIDE-CROSS-LINKED MULTIMERS CONTAINING FIBRILLIN-1
J. Biol. Chem. 2000 275: 2205-2210. [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Rory R. Duncan, Andrea Betz, Michael J. Shipston, Nils Brose, and Robert H. Chow
Transient, phorbol ester-induced DOC2-Munc13 inter- actions in vivo.
J. Biol. Chem. 2000 275: 2246. [Full Text] [PDF]  

Emmanuel Valentin, Farideh Ghomashchi, Michael H. Gelb, Michel Lazdunski, and Gérard Lambeau
On the diversity of secreted phospholipases A2: cloning, tissue distribution, and functional expression of two novel mouse group II enzymes.
J. Biol. Chem. 2000 275: 2246. [Full Text] [PDF]  


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