Editorial:

JBC electronic submission required (starting September 1, 2000)
J. Biol. Chem. 2000 275: 22605. [Full Text] [PDF]  

Minireviews:

David A. Calderwood, Sanford J. Shattil, and Mark H. Ginsberg

Integrins and Actin Filaments: Reciprocal Regulation of Cell Adhesion and Signaling
J. Biol. Chem. 2000 275: 22607-22610. [Full Text] [PDF]  

Accelerated Publications:

Cecile Oury, Emese Toth-Zsamboki, Chris Van Geet, Chantal Thys, Lin Wei, Bernd Nilius, Jos Vermylen, and Marc F. Hoylaerts

A Natural Dominant Negative P2X1 Receptor Due to Deletion of a Single Amino Acid Residue
J. Biol. Chem. 2000 275: 22611-22614. [Abstract] [Full Text] [PDF]  

Kazuaki Nishio and Masato Nakai

Transfer of Iron-Sulfur Cluster from NifU to Apoferredoxin
J. Biol. Chem. 2000 275: 22615-22618. [Abstract] [Full Text] [PDF]  

Zhengming Chen, Ke Guo, Shen Yon Toh, Zhihong Zhou, and Peng Li

Mitochondria Localization and Dimerization Are Required for CIDE-B to Induce Apoptosis
J. Biol. Chem. 2000 275: 22619-22622. [Abstract] [Full Text] [PDF]  

Hirokazu Fujimoto, Keiko Tadano-Aritomi, Ako Tokumasu, Kaoru Ito, Toshiyuki Hikita, Kunihiko Suzuki, and Ineo Ishizuka

Requirement of Seminolipid in Spermatogenesis Revealed by UDP-galactose:Ceramide Galactosyltransferase-deficient Mice
J. Biol. Chem. 2000 275: 22623-22626. [Abstract] [Full Text] [PDF]  

Rieko Ohki, Jiro Nemoto, Hideki Murasawa, Eri Oda, Johji Inazawa, Nobuyuki Tanaka, and Tadatsugu Taniguchi

Reprimo, a New Candidate Mediator of the p53-mediated Cell Cycle Arrest at the G₂ Phase
J. Biol. Chem. 2000 275: 22627-22630. [Abstract] [Full Text] [PDF]  

Dapeng Zhou, Timothy R. Henion, Firoze B. Jungalwala, Eric G. Berger, and Thierry Hennet

The 1,3-Galactosyltransferase 3GalT-V Is a Stage-specific Embryonic Antigen-3 (SSEA-3) Synthase
J. Biol. Chem. 2000 275: 22631-22634. [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Stéphane Koundrioukoff, Zophonías O. Jónsson, Sameez Hasan, Rob N. de Jong, Peter C. van der Vliet, Michael O. Hottiger, and Ulrich Hübscher

A Direct Interaction between Proliferating Cell Nuclear Antigen (PCNA) and Cdk2 Targets PCNA-interacting Proteins for Phosphorylation
J. Biol. Chem. 2000 275: 22882-22887. [Abstract] [Full Text] [PDF]  

Montserrat Soler-López, Lucy Malinina, and Juan A. Subirana

Solvent Organization in an Oligonucleotide Crystal. THE STRUCTURE OF d(GCGAATTCG)₂ AT ATOMIC RESOLUTION
J. Biol. Chem. 2000 275: 23034-23044. [Abstract] [Full Text] [PDF] Supplemental Data  

Mindy Steiniger-White and William S. Reznikoff

The C-terminal  Helix of Tn5 Transposase Is Required for Synaptic Complex Formation
J. Biol. Chem. 2000 275: 23127-23133. [Abstract] [Full Text] [PDF]  

Shiao Li Oei and Mathias Ziegler

ATP for the DNA Ligation Step in Base Excision Repair Is Generated from Poly(ADP-ribose)
J. Biol. Chem. 2000 275: 23234-23239. [Abstract] [Full Text] [PDF]  

Ying Li, Zachary F. Pursell, and Stuart Linn

Identification and Cloning of Two Histone Fold Motif-containing Subunits of HeLa DNA Polymerase
J. Biol. Chem. 2000 275: 23247-23252. [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Martin Münsterkötter, Slobodan Barbaric, and Wolfram Hörz

Transcriptional Regulation of the Yeast PHO8 Promoter in Comparison to the Coregulated PHO5 Promoter
J. Biol. Chem. 2000 275: 22678-22685. [Abstract] [Full Text] [PDF]  

Charbel Massaad, Michel Paradon, Claire Jacques, Colette Salvat, Gilbert Bereziat, Francis Berenbaum, and Jean-Luc Olivier

Induction of Secreted Type IIA Phospholipase A₂ Gene Transcription by Interleukin-1. ROLE OF C/EBP FACTORS
J. Biol. Chem. 2000 275: 22686-22694. [Abstract] [Full Text] [PDF]  

Didier Busso, Anne Keriel, Björn Sandrock, Arnaud Poterszman, Opher Gileadi, and Jean-Marc Egly

Distinct Regions of MAT1 Regulate cdk7 Kinase and TFIIH Transcription Activities
J. Biol. Chem. 2000 275: 22815-22823. [Abstract] [Full Text] [PDF]  

Helena Peilot, Birgitta Rosengren, Göran Bondjers, and Eva Hurt-Camejo

Interferon- Induces Secretory Group IIA Phospholipase A₂ in Human Arterial Smooth Muscle Cells. INVOLVEMENT OF CELL DIFFERENTIATION, STAT-3 ACTIVATION, AND MODULATION BY OTHER CYTOKINES
J. Biol. Chem. 2000 275: 22895-22904. [Abstract] [Full Text] [PDF]  

Heather Mitchell-Felton, R. Bridge Hunter, Eric J. Stevenson, and Susan C. Kandarian

Identification of Weight-bearing-responsive Elements in the Skeletal Muscle Sarco(endo)plasmic Reticulum Ca²⁺ ATPase (SERCA1) Gene
J. Biol. Chem. 2000 275: 23005-23011. [Abstract] [Full Text] [PDF]  

Kim K. C. Li and Kevin A. W. Lee

Transcriptional Activation by the Ewing's Sarcoma (EWS) Oncogene Can Be Cis-repressed by the EWS RNA-binding Domain
J. Biol. Chem. 2000 275: 23053-23058. [Abstract] [Full Text] [PDF]  

Kaylene J. Simpson, Shoba Ranganathan, Juliet A. Fisher, Peter A. Janssens, Denis C. Shaw, and Kevin R. Nicholas

The Gene for a Novel Member of the Whey Acidic Protein Family Encodes Three Four-disulfide Core Domains and Is Asynchronously Expressed during Lactation
J. Biol. Chem. 2000 275: 23074-23081. [Abstract] [Full Text] [PDF]  

Christine Laronga, Heng-Yin Yang, Christopher Neal, and Mong-Hong Lee

Association of the Cyclin-dependent Kinases and 14-3-3 Sigma Negatively Regulates Cell Cycle Progression
J. Biol. Chem. 2000 275: 23106-23112. [Abstract] [Full Text] [PDF]  

Il-Soo Kim, Dong-Hwan Kim, Su-Mi Han, Mi-Uk Chin, Hye-Jung Nam, Hyun-Pil Cho, Sang-Yong Choi, Byung-Joo Song, Eun-Ryoung Kim, Yong-Soo Bae, and Young-Ho Moon

Truncated Form of Importin  Identified in Breast Cancer Cell Inhibits Nuclear Import of p53
J. Biol. Chem. 2000 275: 23139-23145. [Abstract] [Full Text] [PDF]  

Victor N. Uebele, Armando Lagrutta, Theresa Wade, David J. Figueroa, Yuan Liu, Edward McKenna, Christopher P. Austin, Paul B. Bennett, and Richard Swanson

Cloning and Functional Expression of Two Families of -Subunits of the Large Conductance Calcium-activated K⁺ Channel
J. Biol. Chem. 2000 275: 23211-23218. [Abstract] [Full Text] [PDF]  

Sandra K. Winchester, Nagarajan Selvamurugan, Richard C. D'Alonzo, and Nicola C. Partridge

Developmental Regulation of Collagenase-3 mRNA in Normal, Differentiating Osteoblasts through the Activator Protein-1 and the runt Domain Binding Sites
J. Biol. Chem. 2000 275: 23310-23318. [Abstract] [Full Text] [PDF]  

Davide-Carlo Ambrosetti, Hans R. Schöler, Lisa Dailey, and Claudio Basilico

Modulation of the Activity of Multiple Transcriptional Activation Domains by the DNA Binding Domains Mediates the Synergistic Action of Sox2 and Oct-3 on the Fibroblast Growth Factor-4 Enhancer
J. Biol. Chem. 2000 275: 23387-23397. [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Yan Yang, Mark P. Sowden, and Harold C. Smith

Induction of Cytidine to Uridine Editing on Cytoplasmic Apolipoprotein B mRNA by Overexpressing APOBEC-1
J. Biol. Chem. 2000 275: 22663-22669. [Abstract] [Full Text] [PDF]  

Kaiming Xu, Aaron M. Robida, and T. J. Murphy

Immediate-early MEK-1-dependent Stabilization of Rat Smooth Muscle Cell Cyclooxygenase-2 mRNA by G_q-coupled Receptor Signaling
J. Biol. Chem. 2000 275: 23012-23019. [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Satoshi Amano, Ian C. Scott, Kazuhiko Takahara, Manuel Koch, Marie-France Champliaud, Donald R. Gerecke, Douglas R. Keene, David L. Hudson, Toshio Nishiyama, Seungbok Lee, Daniel S. Greenspan, and Robert E. Burgeson

Bone Morphogenetic Protein 1 Is an Extracellular Processing Enzyme of the Laminin 5 2 Chain
J. Biol. Chem. 2000 275: 22728-22735. [Abstract] [Full Text] [PDF]  

Carolyn V. Taylor, Laurent Taupenot, Sushil K. Mahata, Manjula Mahata, Hongjiang Wu, Sukkid Yasothornsrikul, Thomas Toneff, Carlo Caporale, Qijiao Jiang, Robert J. Parmer, Vivian Y. H. Hook, and Daniel T. O'Connor

Formation of the Catecholamine Release-inhibitory Peptide Catestatin from Chromogranin A. DETERMINATION OF PROTEOLYTIC CLEAVAGE SITES IN HORMONE STORAGE GRANULES
J. Biol. Chem. 2000 275: 22905-22915. [Abstract] [Full Text] [PDF]  

Jinyi Shao, Hongmiao Sheng, Raymond N. DuBois, and R. Daniel Beauchamp

Oncogenic Ras-mediated Cell Growth Arrest and Apoptosis are Associated with Increased Ubiquitin-dependent Cyclin D1 Degradation
J. Biol. Chem. 2000 275: 22916-22924. [Abstract] [Full Text] [PDF]  

Ilia V. Davydov and Alexander Varshavsky

RGS4 Is Arginylated and Degraded by the N-end Rule Pathway in Vitro
J. Biol. Chem. 2000 275: 22931-22941. [Abstract] [Full Text] [PDF]  

Alexander A. Vostrov and Wolfgang W. Quitschke

Plasma Hyaluronan-binding Protein Is a Serine Protease
J. Biol. Chem. 2000 275: 22978-22985. [Abstract] [Full Text] [PDF]  

Dong-Seok Lee, Susumu Tomita, Yutaka Kirino, and Toshiharu Suzuki

Regulation of X11L-dependent Amyloid Precursor Protein Metabolism by XB51, a Novel X11L-binding Protein
J. Biol. Chem. 2000 275: 23134-23138. [Abstract] [Full Text] [PDF]  

Yuichiro Higashimoto, Shin'ichi Saito, Xiao-He Tong, Anita Hong, Kazuyasu Sakaguchi, Ettore Appella, and Carl W. Anderson

Human p53 Is Phosphorylated on Serines 6 and 9 in Response to DNA Damage-inducing Agents
J. Biol. Chem. 2000 275: 23199-23203. [Abstract] [Full Text] [PDF]  

Ryan Bingham, Stephen I. N. Ekunwe, Sherry Falk, Larry Snyder, and Colin Kleanthous

The Major Head Protein of Bacteriophage T4 Binds Specifically to Elongation Factor Tu
J. Biol. Chem. 2000 275: 23219-23226. [Abstract] [Full Text] [PDF]  

Kizhakkekara R. Santhamma and Indira Sen

Specific Cellular Proteins Associate with Angiotensin-converting Enzyme and Regulate Its Intracellular Transport and Cleavage-Secretion
J. Biol. Chem. 2000 275: 23253-23258. [Abstract] [Full Text] [PDF]  

P. David Toman, George Chisholm, Hugh McMullin, Lynne M. Giere, David R. Olsen, Robert J. Kovach, Scott D. Leigh, Bryant E. Fong, Robert Chang, Gregory A. Daniels, Richard A. Berg, and Ronald A. Hitzeman

Production of Recombinant Human Type I Procollagen Trimers Using a Four-gene Expression System in the Yeast Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 23303-23309. [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

William Garzon-Rodriguez, Art Vega, Marisa Sepulveda-Becerra, Saskia Milton, David A. Johnson, Anatoly K. Yatsimirsky, and Charles G. Glabe

A Conformation Change in the Carboxyl Terminus of Alzheimer's A(1-40) Accompanies the Transition from Dimer to Fibril as Revealed by Fluorescence Quenching Analysis
J. Biol. Chem. 2000 275: 22645-22649. [Abstract] [Full Text] [PDF]  

Grzegorz Kudla, Sylvie Montessuit, Robert Eskes, Catherine Berrier, Jean-Claude Martinou, Alexandre Ghazi, and Bruno Antonsson

The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal Fragment
J. Biol. Chem. 2000 275: 22713-22718. [Abstract] [Full Text] [PDF]  

Shouchun Liu and Mark H. Ginsberg

Paxillin Binding to a Conserved Sequence Motif in the ₄ Integrin Cytoplasmic Domain
J. Biol. Chem. 2000 275: 22736-22742. [Abstract] [Full Text] [PDF]  

Xiu-xia Sun and Chih-chen Wang

The N-terminal Sequence (Residues 1-65) Is Essential for Dimerization, Activities, and Peptide Binding of Escherichia coli DsbC
J. Biol. Chem. 2000 275: 22743-22749. [Abstract] [Full Text] [PDF]  

Meredith F. N. Rosser and Christopher V. Nicchitta

Ligand Interactions in the Adenosine Nucleotide-binding Domain of the Hsp90 Chaperone, GRP94. I. EVIDENCE FOR ALLOSTERIC REGULATION OF LIGAND BINDING
J. Biol. Chem. 2000 275: 22798-22805. [Abstract] [Full Text] [PDF]  

James J. Wassenberg, Robyn C. Reed, and Christopher V. Nicchitta

Ligand Interactions in the Adenosine Nucleotide-binding Domain of the Hsp90 Chaperone, GRP94. II. LIGAND-MEDIATED ACTIVATION OF GRP94 MOLECULAR CHAPERONE AND PEPTIDE BINDING ACTIVITY
J. Biol. Chem. 2000 275: 22806-22814. [Abstract] [Full Text] [PDF]  

Per Hammarström, Malin Persson, Rikard Owenius, Mikael Lindgren, and Uno Carlsson

Protein Substrate Binding Induces Conformational Changes in the Chaperonin GroEL. A SUGGESTED MECHANISM FOR UNFOLDASE ACTIVITY
J. Biol. Chem. 2000 275: 22832-22838. [Abstract] [Full Text] [PDF]  

Wei Wang, Mariko Nagashima, Mark Schneider, John Morser, and Michael Nesheim

Elements of the Primary Structure of Thrombomodulin Required for Efficient Thrombin-activable Fibrinolysis Inhibitor Activation
J. Biol. Chem. 2000 275: 22942-22947. [Abstract] [Full Text] [PDF]  

Simon R. Andrews, Simon J. Charnock, Jeremy H. Lakey, Gideon J. Davies, Marc Claeyssens, Wim Nerinckx, Melanie Underwood, Michael L. Sinnott, R. Antony J. Warren, and Harry J. Gilbert

Substrate Specificity in Glycoside Hydrolase Family 10. TYROSINE 87 AND LEUCINE 314 PLAY A PIVOTAL ROLE IN DISCRIMINATING BETWEEN GLUCOSE AND XYLOSE BINDING IN THE PROXIMAL ACTIVE SITE OF PSEUDOMONAS CELLULOSA XYLANASE 10A
J. Biol. Chem. 2000 275: 23027-23033. [Abstract] [Full Text] [PDF]  

Arthur J. Weaver, William P. Sullivan, Sara J. Felts, Barbara A. L. Owen, and David O. Toft

Crystal Structure and Activity of Human p23, a Heat Shock Protein 90 Co-chaperone
J. Biol. Chem. 2000 275: 23045-23052. [Abstract] [Full Text] [PDF]  

Brian M. McDermott, Jr., Ann H. Rux, Roselyn J. Eisenberg, Gary H. Cohen, and Vincent R. Racaniello

Two Distinct Binding Affinities of Poliovirus for Its Cellular Receptor
J. Biol. Chem. 2000 275: 23089-23096. [Abstract] [Full Text] [PDF]  

George B. Cohen, Vangipuram S. Rangan, Benjamin K. Chen, Stuart Smith, and David Baltimore

The Human Thioesterase II Protein Binds to a Site on HIV-1 Nef Critical for CD4 Down-regulation
J. Biol. Chem. 2000 275: 23097-23105. [Abstract] [Full Text] [PDF]  

Terrance M. Arthur, Larry C. Anthony, and Richard R. Burgess

Mutational Analysis of '_260-309, a ⁷⁰ Binding Site Located on Escherichia coli Core RNA Polymerase
J. Biol. Chem. 2000 275: 23113-23119. [Abstract] [Full Text] [PDF]  

Mark J. Jedrzejas, Monica Chander, Peter Setlow, and Gunasekaran Krishnasamy

Mechanism of Catalysis of the Cofactor-independent Phosphoglycerate Mutase from Bacillus stearothermophilus. CRYSTAL STRUCTURE OF THE COMPLEX WITH 2-PHOSPHOGLYCERATE
J. Biol. Chem. 2000 275: 23146-23153. [Abstract] [Full Text] [PDF]  

Chia-Cheng Chou, Yuh-Ju Sun, Menghsiao Meng, and Chwan-Deng Hsiao

The Crystal Structure of Phosphoglucose Isomerase/Autocrine Motility Factor/Neuroleukin Complexed with Its Carbohydrate Phosphate Inhibitors Suggests Its Substrate/Receptor Recognition
J. Biol. Chem. 2000 275: 23154-23160. [Abstract] [Full Text] [PDF]  

David M. Hoover, Laura S. Mizoue, Tracy M. Handel, and Jacek Lubkowski

The Crystal Structure of the Chemokine Domain of Fractalkine Shows a Novel Quaternary Arrangement
J. Biol. Chem. 2000 275: 23187-23193. [Abstract] [Full Text] [PDF]  

Xavier Morelli, Mirjam Czjzek, Claude E. Hatchikian, Olivier Bornet, Juan C. Fontecilla-Camps, Nuno P. Palma, Jose J. G. Moura, and Françoise Guerlesquin

Structural Model of the Fe-Hydrogenase/Cytochrome c₅₅₃ Complex Combining Transverse Relaxation-optimized Spectroscopy Experiments and Soft Docking Calculations
J. Biol. Chem. 2000 275: 23204-23210. [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Isabella Feierberg, Victor Luzhkov, and Johan Åqvist

Computer Simulation of Primary Kinetic Isotope Effects in the Proposed Rate-limiting Step of the Glyoxalase I Catalyzed Reaction
J. Biol. Chem. 2000 275: 22657-22662. [Abstract] [Full Text] [PDF]  

Miklós Sahin-Tóth

Human Cationic Trypsinogen. ROLE OF Asn-21 IN ZYMOGEN ACTIVATION AND IMPLICATIONS IN HEREDITARY PANCREATITIS
J. Biol. Chem. 2000 275: 22750-22755. [Abstract] [Full Text] [PDF]  

Henry S. Duewel and Ronald W. Woodard

A Metal Bridge between Two Enzyme Families. 3-DEOXY-D-MANNO-OCTULOSONATE-8-PHOSPHATE SYNTHASE FROM AQUIFEX AEOLICUS REQUIRES A DIVALENT METAL FOR ACTIVITY
J. Biol. Chem. 2000 275: 22824-22831. [Abstract] [Full Text] [PDF]  

Charity Crews, Keith D. Wilkinson, Lance Wells, Charles Perkins, and Judith L. Fridovich-Keil

Functional Consequence of Substitutions at Residue 171 in Human Galactose-1-phosphate Uridylyltransferase
J. Biol. Chem. 2000 275: 22847-22853. [Abstract] [Full Text] [PDF]  

Günther Regelsberger, Christa Jakopitsch, Florian Rüker, Daniel Krois, Günter A. Peschek, and Christian Obinger

Effect of Distal Cavity Mutations on the Formation of Compound I in Catalase-Peroxidases
J. Biol. Chem. 2000 275: 22854-22861. [Abstract] [Full Text] [PDF]  

Monalisa Chatterji, Shyam Unniraman, Anthony Maxwell, and Valakunja Nagaraja

The Additional 165 Amino Acids in the B Protein of Escherichia coli DNA Gyrase Have an Important Role in DNA Binding
J. Biol. Chem. 2000 275: 22888-22894. [Abstract] [Full Text] [PDF]  

Edward A. Weinstein, Hongwei Li, John A. Lawson, Joshua Rokach, Garret A. FitzGerald, and Paul H. Axelsen

Prothrombinase Acceleration by Oxidatively Damaged Phospholipids
J. Biol. Chem. 2000 275: 22925-22930. [Abstract] [Full Text] [PDF]  

Valérie Ducros, Simon J. Charnock, Urszula Derewenda, Zygmunt S. Derewenda, Zbigniew Dauter, Claude Dupont, François Shareck, Rolf Morosoli, Dieter Kluepfel, and Gideon J. Davies

Substrate Specificity in Glycoside Hydrolase Family 10. STRUCTURAL AND KINETIC ANALYSIS OF THE STREPTOMYCES LIVIDANS XYLANASE 10A
J. Biol. Chem. 2000 275: 23020-23026. [Abstract] [Full Text] [PDF]  

Takashi Yamada, Christophe Morisseau, Joseph E. Maxwell, Maria A. Argiriadi, David W. Christianson, and Bruce D. Hammock

Biochemical Evidence for the Involvement of Tyrosine in Epoxide Activation during the Catalytic Cycle of Epoxide Hydrolase
J. Biol. Chem. 2000 275: 23082-23088. [Abstract] [Full Text] [PDF]  

Tianxin Yang, Yuning Huang, Lynn E. Heasley, Tomas Berl, Jurgen B. Schnermann, and Josephine P. Briggs

MAPK Mediation of Hypertonicity-stimulated Cyclooxygenase-2 Expression in Renal Medullary Collecting Duct Cells
J. Biol. Chem. 2000 275: 23281-23286. [Abstract] [Full Text] [PDF]  

Takashi Morishige, Tetsuya Tsujita, Yasuyuki Yamada, and Fumihiko Sato

Molecular Characterization of the S-Adenosyl-L-methionine:3'-Hydroxy-N-methylcoclaurine 4'-O-Methyltransferase Involved in Isoquinoline Alkaloid Biosynthesis in Coptis japonica
J. Biol. Chem. 2000 275: 23398-23405. [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Russell T. Matthews, Sydney C. Gary, Cynthia Zerillo, Michael Pratta, Kimberly Solomon, Elizabeth C. Arner, and Susan Hockfield

Brain-enriched Hyaluronan Binding (BEHAB)/Brevican Cleavage in a Glioma Cell Line Is Mediated by a Disintegrin and Metalloproteinase with Thrombospondin Motifs (ADAMTS) Family Member
J. Biol. Chem. 2000 275: 22695-22703. [Abstract] [Full Text] [PDF]  

C. S. K. Mayanil, David George, Barbara Mania-Farnell, Christopher L. Bremer, David G. McLone, and Eric G. Bremer

Overexpression of Murine Pax3 Increases NCAM Polysialylation in a Human Medulloblastoma Cell Line
J. Biol. Chem. 2000 275: 23259-23266. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Mark C. Schulbach, Patrick J. Brennan, and Dean C. Crick

Identification of a Short (C₁₅) Chain Z-Isoprenyl Diphosphate Synthase and a Homologous Long (C₅₀) Chain Isoprenyl Diphosphate Synthase in Mycobacterium tuberculosis
J. Biol. Chem. 2000 275: 22876-22881. [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Shinobu Iwaki, Norihisa Tamura, Tomomi Kimura-Someya, Shigeyuki Nada, and Akihito Yamaguchi

Cysteine-scanning Mutagenesis of Transmembrane Segments 4 and 5 of the Tn10-encoded Metal-Tetracycline/H⁺ Antiporter Reveals a Permeability Barrier in the Middle of a Transmembrane Water-filled Channel
J. Biol. Chem. 2000 275: 22704-22712. [Abstract] [Full Text] [PDF]  

Sean M. O'Shea and Neil L. Harrison

Arg-274 and Leu-277 of the -Aminobutyric Acid Type A Receptor ₂ Subunit Define Agonist Efficacy and Potency
J. Biol. Chem. 2000 275: 22764-22768. [Abstract] [Full Text] [PDF]  

Dongdong Yao, Bryan Mackenzie, Hong Ming, Hélène Varoqui, Heming Zhu, Matthias A. Hediger, and Jeffrey D. Erickson

A Novel System A Isoform Mediating Na⁺/Neutral Amino Acid Cotransport
J. Biol. Chem. 2000 275: 22790-22797. [Abstract] [Full Text] [PDF]  

Ron Ortenberg and Moshe Mevarech

Evidence for Post-translational Membrane Insertion of the Integral Membrane Protein Bacterioopsin Expressed in the Heterologous Halophilic Archaeon Haloferax volcanii
J. Biol. Chem. 2000 275: 22839-22846. [Abstract] [Full Text] [PDF]  

Li Wang, Christian Ungermann, and William Wickner

The Docking of Primed Vacuoles Can Be Reversibly Arrested by Excess Sec17p (-SNAP)
J. Biol. Chem. 2000 275: 22862-22867. [Abstract] [Full Text] [PDF]  

Sixue Chen and Barbara Ann Halkier

Characterization of Glucosinolate Uptake by Leaf Protoplasts of Brassica napus
J. Biol. Chem. 2000 275: 22955-22960. [Abstract] [Full Text] [PDF]  

Minggui Chen, Zhimin Zhang, Mary-Anne Tawiah-Boateng, and Peter M. D. Hardwicke

A Ca²⁺-dependent Tryptic Cleavage Site and a Protein Kinase A Phosphorylation Site Are Present in the Ca²⁺ Regulatory Domain of Scallop Muscle Na⁺-Ca²⁺ Exchanger
J. Biol. Chem. 2000 275: 22961-22968. [Abstract] [Full Text] [PDF]  

Jörg König, Yunhai Cui, Anne T. Nies, and Dietrich Keppler

Localization and Genomic Organization of a New Hepatocellular Organic Anion Transporting Polypeptide
J. Biol. Chem. 2000 275: 23161-23168. [Abstract] [Full Text] [PDF]  

Catherine Proenza, Christina Wilkens, Nancy M. Lorenzon, and Kurt G. Beam

A Carboxyl-terminal Region Important for the Expression and Targeting of the Skeletal Muscle Dihydropyridine Receptor
J. Biol. Chem. 2000 275: 23169-23174. [Abstract] [Full Text] [PDF]  

Jürgen Wastl and Uwe-G. Maier

Transport of Proteins into Cryptomonads Complex Plastids
J. Biol. Chem. 2000 275: 23194-23198. [Abstract] [Full Text] [PDF]  

Xavier De Deken, Dantong Wang, Marie-Christine Many, Sabine Costagliola, Frédérick Libert, Gilbert Vassart, Jacques E. Dumont, and Françoise Miot

Cloning of Two Human Thyroid cDNAs Encoding New Members of the NADPH Oxidase Family
J. Biol. Chem. 2000 275: 23227-23233. [Abstract] [Full Text] [PDF]  

Aileen L. Green, Ethan J. Anderson, and Robert J. Brooker

A Revised Model for the Structure and Function of the Lactose Permease. EVIDENCE THAT A FACE ON TRANSMEMBRANE SEGMENT 2 IS IMPORTANT FOR CONFORMATIONAL CHANGES
J. Biol. Chem. 2000 275: 23240-23246. [Abstract] [Full Text] [PDF]  

Fang Zhang, Wandong Zhang, Lin Liu, Cynthia L. Fisher, David Hui, Sarah Childs, Katerina Dorovini-Zis, and Victor Ling

Characterization of ABCB9, an ATP Binding Cassette Protein Associated with Lysosomes
J. Biol. Chem. 2000 275: 23287-23294. [Abstract] [Full Text] [PDF]  

Jiantao Ding, Zhao Wu, Bill P. Crider, Yongming Ma, Xinji Li, Clive Slaughter, Limin Gong, and Xiao-Song Xie

Identification and Functional Expression of Four Isoforms of ATPase II, the Putative Aminophospholipid Translocase. EFFECT OF ISOFORM VARIATION ON THE ATPase ACTIVITY AND PHOSPHOLIPID SPECIFICITY
J. Biol. Chem. 2000 275: 23378-23386. [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Jie Yang, Thomas D. Hurley, and Anna A. DePaoli-Roach

Interaction of Inhibitor-2 with the Catalytic Subunit of Type 1 Protein Phosphatase. IDENTIFICATION OF A SEQUENCE ANALOGOUS TO THE CONSENSUS TYPE 1 PROTEIN PHOSPHATASE-BINDING MOTIF
J. Biol. Chem. 2000 275: 22635-22644. [Abstract] [Full Text] [PDF]  

Dana M. Pirone, Shigetomo Fukuhara, J. Silvio Gutkind, and Peter D. Burbelo

SPECs, Small Binding Proteins for Cdc42
J. Biol. Chem. 2000 275: 22650-22656. [Abstract] [Full Text] [PDF]  

Johanna M. Lindquist, J. Magnus Fredriksson, Stefan Rehnmark, Barbara Cannon, and Jan Nedergaard

₃- and ₁-Adrenergic Erk1/2 Activation Is Src- but Not G_i-mediated in Brown Adipocytes
J. Biol. Chem. 2000 275: 22670-22677. [Abstract] [Full Text] [PDF]  

Matthew Stoner, Fan Wang, Mark Wormke, Thu Nguyen, Ismael Samudio, Carrie Vyhlidal, Dieter Marme, Gunter Finkenzeller, and Stephen Safe

Inhibition of Vascular Endothelial Growth Factor Expression in HEC1A Endometrial Cancer Cells through Interactions of Estrogen Receptor  and Sp3 Proteins
J. Biol. Chem. 2000 275: 22769-22779. [Abstract] [Full Text] [PDF]  

Klaus Schwamborn, Robert Weil, Gilles Courtois, Simon T. Whiteside, and Alain Israël

Phorbol Esters and Cytokines Regulate the Expression of the NEMO-related Protein, a Molecule Involved in a NF-B-independent Pathway
J. Biol. Chem. 2000 275: 22780-22789. [Abstract] [Full Text] [PDF]  

Heng Zhou, Anning Lin, Zhennan Gu, Sam Chen, No-Hee Park, and Robert Chiu

12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced c-Jun N-terminal Kinase (JNK) Phosphatase Renders Immortalized or Transformed Epithelial Cells Refractory to TPA-inducible JNK Activity
J. Biol. Chem. 2000 275: 22868-22875. [Abstract] [Full Text] [PDF]  

María E. Castelli, Eleonora García Véscovi, and Fernando C. Soncini

The Phosphatase Activity Is the Target for Mg²⁺ Regulation of the Sensor Protein PhoQ in Salmonella
J. Biol. Chem. 2000 275: 22948-22954. [Abstract] [Full Text] [PDF]  

Bin He, Jon A. Kemppainen, and Elizabeth M. Wilson

FXXLF and WXXLF Sequences Mediate the NH₂-terminal Interaction with the Ligand Binding Domain of the Androgen Receptor
J. Biol. Chem. 2000 275: 22986-22994. [Abstract] [Full Text] [PDF]  

Christopher D. Krause, Charles A. Lunn, Lara S. Izotova, Olga Mirochnitchenko, Sergei V. Kotenko, Daniel J. Lundell, Satwant K. Narula, and Sidney Pestka

Signaling by Covalent Heterodimers of Interferon-. EVIDENCE FOR ONE-SIDED SIGNALING IN THE ACTIVE TETRAMERIC RECEPTOR COMPLEX
J. Biol. Chem. 2000 275: 22995-23004. [Abstract] [Full Text] [PDF]  

Kersten M. Small, Susan L. Forbes, Fahema F. Rahman, Kari M. Bridges, and Stephen B. Liggett

A Four Amino Acid Deletion Polymorphism in the Third Intracellular Loop of the Human _2C-Adrenergic Receptor Confers Impaired Coupling to Multiple Effectors
J. Biol. Chem. 2000 275: 23059-23064. [Abstract] [Full Text] [PDF]  

S. Courtney Frasch, Peter M. Henson, Jenai M. Kailey, Donald A. Richter, Michael S. Janes, Valerie A. Fadok, and Donna L. Bratton

Regulation of Phospholipid Scramblase Activity during Apoptosis and Cell Activation by Protein Kinase C
J. Biol. Chem. 2000 275: 23065-23073. [Abstract] [Full Text] [PDF]  

Stéphane A. Laporte, Robert H. Oakley, Jason A. Holt, Larry S. Barak, and Marc G. Caron

The Interaction of -Arrestin with the AP-2 Adaptor Is Required for the Clustering of ₂-Adrenergic Receptor into Clathrin-coated Pits
J. Biol. Chem. 2000 275: 23120-23126. [Abstract] [Full Text] [PDF]  

Andy McShea, Temesgen Samuel, Jason-Thomas Eppel, Denise A. Galloway, and Jens Oliver Funk

Identification of CIP-1-associated Regulator of Cyclin B (CARB), a Novel p21-binding Protein Acting in the G₂ Phase of the Cell Cycle
J. Biol. Chem. 2000 275: 23181-23186. [Abstract] [Full Text] [PDF]  

Michael L. Schlador, Robert D. Grubbs, and Neil M. Nathanson

Multiple Topological Domains Mediate Subtype-specific Internalization of the M₂ Muscarinic Acetylcholine Receptor
J. Biol. Chem. 2000 275: 23295-23302. [Abstract] [Full Text] [PDF]  

Gordon W. McLean, Valerie J. Fincham, and Margaret C. Frame

v-Src Induces Tyrosine Phosphorylation of Focal Adhesion Kinase Independently of Tyrosine 397 and Formation of a Complex with Src
J. Biol. Chem. 2000 275: 23333-23339. [Abstract] [Full Text] [PDF]  

Liwu Li, Sue Cousart, Jean Hu, and Charles E. McCall

Characterization of Interleukin-1 Receptor-associated Kinase in Normal and Endotoxin-tolerant Cells
J. Biol. Chem. 2000 275: 23340-23345. [Abstract] [Full Text] [PDF]  

Rachel M. Kulansky Poltilove, Aviva R. Jacobs, Carol Renfrew Haft, Pin Xu, and Simeon I. Taylor

Characterization of Drosophila Insulin Receptor Substrate
J. Biol. Chem. 2000 275: 23346-23354. [Abstract] [Full Text] [PDF]  

Weiguo Zhang, Ronald P. Trible, Minghua Zhu, Stanley K. Liu, C. Jane McGlade, and Lawrence E. Samelson

Association of Grb2, Gads, and Phospholipase C-1 with Phosphorylated LAT Tyrosine Residues. EFFECT OF LAT TYROSINE MUTATIONS ON T CELL ANTIGEN RECEPTOR-MEDIATED SIGNALING
J. Biol. Chem. 2000 275: 23355-23361. [Abstract] [Full Text] [PDF]  

J. Paul Mounsey, J. Edward John, III, Steve M. Helmke, Erik W. Bush, John Gilbert, Allen D. Roses, M. Benjamin Perryman, Larry R. Jones, and J. Randall Moorman

Phospholemman Is a Substrate for Myotonic Dystrophy Protein Kinase
J. Biol. Chem. 2000 275: 23362-23367. [Abstract] [Full Text] [PDF]  

Ferruccio Galbiati, Daniela Volonte', Anthony M. C. Brown, David E. Weinstein, Avri Ben-Ze'ev, Richard G. Pestell, and Michael P. Lisanti

Caveolin-1 Expression Inhibits Wnt/-Catenin/Lef-1 Signaling by Recruiting -Catenin to Caveolae Membrane Domains
J. Biol. Chem. 2000 275: 23368-23377. [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Ted O'Neill, Alison J. Dwyer, Yael Ziv, Doug W. Chan, Susan P. Lees-Miller, Robert H. Abraham, Jack H. Lai, David Hill, Yossi Shiloh, Lewis C. Cantley, and Gary A. Rathbun

Utilization of Oriented Peptide Libraries to Identify Substrate Motifs Selected by ATM
J. Biol. Chem. 2000 275: 22719-22727. [Abstract] [Full Text] [PDF]  

Harlan N. Bradford, Robin A. Pixley, and Robert W. Colman

Human Factor XII Binding to the Glycoprotein Ib-IX-V Complex Inhibits Thrombin-induced Platelet Aggregation
J. Biol. Chem. 2000 275: 22756-22763. [Abstract] [Full Text] [PDF]  

Dhaya Seshasayee, Justin N. Geiger, Peter Gaines, and Don M. Wojchowski

Intron 1 Elements Promote Erythroid-specific GATA-1 Gene Expression
J. Biol. Chem. 2000 275: 22969-22977. [Abstract] [Full Text] [PDF]  

Susanne M. Steggerda and Bryce M. Paschal

The Mammalian Mog1 Protein Is a Guanine Nucleotide Release Factor for Ran
J. Biol. Chem. 2000 275: 23175-23180. [Abstract] [Full Text] [PDF]  

Thomas J. Leach, Maria Mazzeo, Heather L. Chotkowski, James P. Madigan, Michael G. Wotring, and Robert L. Glaser

Histone H2A.Z Is Widely but Nonrandomly Distributed in Chromosomes of Drosophila melanogaster
J. Biol. Chem. 2000 275: 23267-23272. [Abstract] [Full Text] [PDF]  

Richard J. Siviter, Geoffrey M. Coast, Åsa M. E. Winther, Ronald J. Nachman, Christine A. M. Taylor, Alan D. Shirras, David Coates, R. Elwyn Isaac, and Dick R. Nässel

Expression and Functional Characterization of a Drosophila Neuropeptide Precursor with Homology to Mammalian Preprotachykinin A
J. Biol. Chem. 2000 275: 23273-23280. [Abstract] [Full Text] [PDF]  

Alemseged Truneh, Sunita Sharma, Carol Silverman, Sanjay Khandekar, Manjula P. Reddy, Keith C. Deen, Megan M. Mclaughlin, Srinivasa M. Srinivasula, George P. Livi, Lisa A. Marshall, Emad S. Alnemri, William V. Williams, and Michael L. Doyle

Temperature-sensitive Differential Affinity of TRAIL for Its Receptors. DR5 IS THE HIGHEST AFFINITY RECEPTOR
J. Biol. Chem. 2000 275: 23319-23325. [Abstract] [Full Text] [PDF]  

Yu Cheng, Igor Zhizhin, Robert L. Perlman, and Dimitra Mangoura

Prolactin-induced Cell Proliferation in PC12 Cells Depends on JNK but Not ERK Activation
J. Biol. Chem. 2000 275: 23326-23332. [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Irmgard Ziegler, Thomas McDonald, Christian Hesslinger, Isabelle Pelletier, and Peter Boyle

Development of the pteridine pathway in the zebrafish, Danio rerio.
J. Biol. Chem. 2000 275: 23406. [Full Text] [PDF]  

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