JBC -- Table of Contents (Aug 11 2000, 275, (32))

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Editorial:

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J. Biol. Chem. 2000 275: 24231. [Full Text] [PDF]

Minireviews:

Anne Woods and John R. Couchman: Integrin Modulation by Lateral Association
J. Biol. Chem. 2000 275: 24233-24236. [Full Text] [PDF]

DNA: Replication Repair and Recombination:

Yoshito Okada, Yasutomo Ito, Akihiko Kikuchi, Yuji Nimura, Shonen Yoshida, and Motoshi Suzuki: Assignment of Functional Amino Acids around the Active Site of Human DNA Topoisomerase II $alpha$
J. Biol. Chem. 2000 275: 24630-24638. [Abstract] [Full Text] [PDF]

Wu-Po Ma, Michael W. Kaiser, Natasha Lyamicheva, James J. Schaefer, Hatim T. Allawi, Tsetska Takova, Bruce P. Neri, and Victor I. Lyamichev: RNA Template-dependent 5' Nuclease Activity of Thermus aquaticus and Thermus thermophilus DNA Polymerases
J. Biol. Chem. 2000 275: 24693-24700. [Abstract] [Full Text] [PDF]

Kenjiro Asagoshi, Takao Yamada, Yumiko Okada, Hiroaki Terato, Yoshihiko Ohyama, Shuji Seki, and Hiroshi Ide: Recognition of Formamidopyrimidine by Escherichia coli and Mammalian Thymine Glycol Glycosylases. DISTINCTIVE PAIRED BASE EFFECTS AND BIOLOGICAL AND MECHANISTIC IMPLICATIONS
J. Biol. Chem. 2000 275: 24781-24786. [Abstract] [Full Text] [PDF]

Johannes N. Spelbrink, Janne M. Toivonen, Gerrit A. J. Hakkaart, Johanna M. Kurkela, Helen M. Cooper, Sanna K. Lehtinen, Nicolas Lecrenier, Jaap Willem Back, Dave Speijer, Françoise Foury, and Howard T. Jacobs: In Vivo Functional Analysis of the Human Mitochondrial DNA Polymerase POLG Expressed in Cultured Human Cells
J. Biol. Chem. 2000 275: 24818-24828. [Abstract] [Full Text] [PDF]

Laura Fouassier, C. Chris Yun, J. Gregory Fitz, and R. Brian Doctor: Evidence for Ezrin-Radixin-Moesin-binding Phosphoprotein 50 (EBP50) Self-association through PDZ-PDZ Interactions
J. Biol. Chem. 2000 275: 25039-25045. [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Shu-Yuan Chiang, Roland W. Bürli, Chris C. Benz, Loretta Gawron, Gary K. Scott, Peter B. Dervan, and Terry A. Beerman: Targeting the Ets Binding Site of the HER2/neu Promoter with Pyrrole-Imidazole Polyamides
J. Biol. Chem. 2000 275: 24246-24254. [Abstract] [Full Text] [PDF]

Silke I. Patzer and Klaus Hantke: The Zinc-responsive Regulator Zur and Its Control of the znu Gene Cluster Encoding the ZnuABC Zinc Uptake System in Escherichia coli
J. Biol. Chem. 2000 275: 24321-24332. [Abstract] [Full Text] [PDF]

Mark Meininghaus, Rob D. Chapman, Manuela Horndasch, and Dirk Eick: Conditional Expression of RNA Polymerase II in Mammalian Cells. DELETION OF THE CARBOXYL-TERMINAL DOMAIN OF THE LARGE SUBUNIT AFFECTS EARLY STEPS IN TRANSCRIPTION
J. Biol. Chem. 2000 275: 24375-24382. [Abstract] [Full Text] [PDF]

Christopher B. Phelps, Lei Lei Sengchanthalangsy, Shiva Malek, and Gourisankar Ghosh: Mechanism of $kappa$ B DNA binding by Rel/NF- $kappa$ B dimers
J. Biol. Chem. 2000 275: 24392-24399. [Abstract] [Full Text] [PDF]

Lucía Escolar, José Pérez-Martín, and Víctor de Lorenzo: Evidence of an Unusually Long Operator for the Fur Repressor in the Aerobactin Promoter of Escherichia coli
J. Biol. Chem. 2000 275: 24709-24714. [Abstract] [Full Text] [PDF]

Ludwig Wagner, Olena Oliyarnyk, Wolfgang Gartner, Peter Nowotny, Marion Groeger, Klaus Kaserer, Werner Waldhäusl, and Mark S. Pasternack: Cloning and Expression of Secretagogin, a Novel Neuroendocrine- and Pancreatic Islet of Langerhans-specific Ca²⁺-binding Protein
J. Biol. Chem. 2000 275: 24740-24751. [Abstract] [Full Text] [PDF]

Philippe Wiesel, Lauren C. Foster, Andrea Pellacani, Matthew D. Layne, Chung-Ming Hsieh, Gordon S. Huggins, Phyllis Strauss, Shaw-Fang Yet, and Mark A. Perrella: Thioredoxin Facilitates the Induction of Heme Oxygenase-1 in Response to Inflammatory Mediators
J. Biol. Chem. 2000 275: 24840-24846. [Abstract] [Full Text] [PDF]

Lori L. Knoop and Suzanne J. Baker: The Splicing Factor U1C Represses EWS/FLI-mediated Transactivation
J. Biol. Chem. 2000 275: 24865-24871. [Abstract] [Full Text] [PDF]

Douglas S. Millar, Cheryl L. Paul, Peter L. Molloy, and Susan J. Clark: A Distinct Sequence (ATAAA)_n Separates Methylated and Unmethylated Domains at the 5'-End of the GSTP1 CpG Island*
J. Biol. Chem. 2000 275: 24893-24899. [Abstract] [Full Text] [PDF] Supplemental Data

Ramon Sendra, Christin Tse, and Jeffrey C. Hansen: The Yeast Histone Acetyltransferase A2 Complex, but Not Free Gcn5p, Binds Stably to Nucleosomal Arrays
J. Biol. Chem. 2000 275: 24928-24934. [Abstract] [Full Text] [PDF]

Nuria E. Vilaboa, Alba Galán, Alfonso Troyano, Elena de Blas, and Patricio Aller: Regulation of Multidrug Resistance 1 (MDR1)/P-glycoprotein Gene Expression and Activity by Heat-Shock Transcription Factor 1 (HSF1)
J. Biol. Chem. 2000 275: 24970-24976. [Abstract] [Full Text] [PDF]

RNA: Structure Metabolism and Catalysis:

Berndt Müller, Julia Link, and Carl Smythe: Assembly of U7 Small Nuclear Ribonucleoprotein Particle and Histone RNA 3' Processing in Xenopus Egg Extracts
J. Biol. Chem. 2000 275: 24284-24293. [Abstract] [Full Text] [PDF]

Jeffrey A. Kowalak, Eveline Bruenger, Pamela F. Crain, and James A. McCloskey: Identities and Phylogenetic Comparisons of Posttranscriptional Modifications in 16 S Ribosomal RNA from Haloferax volcanii
J. Biol. Chem. 2000 275: 24484-24489. [Abstract] [Full Text] [PDF]

Yin Hew, Connie Lau, Zbyszko Grzelczak, and Fred W. Keeley: Identification of a GA-rich Sequence as a Protein-binding Site in the 3'-Untranslated Region of Chicken Elastin mRNA with a Potential Role in the Developmental Regulation of Elastin mRNA Stability
J. Biol. Chem. 2000 275: 24857-24864. [Abstract] [Full Text] [PDF]

Protein Synthesis Post-Translation Modification and Degradation:

Alexa Raney, Anita C. Baron, Gregory J. Mize, G. Lynn Law, and David R. Morris: In Vitro Translation of the Upstream Open Reading Frame in the Mammalian mRNA Encoding S-Adenosylmethionine Decarboxylase
J. Biol. Chem. 2000 275: 24444-24450. [Abstract] [Full Text] [PDF]

Rebecca Webel, Indu Menon, Joseph E. O'Tousa, and Nansi Jo Colley: Role of Asparagine-linked Oligosaccharides in Rhodopsin Maturation and Association with Its Molecular Chaperone, NinaA
J. Biol. Chem. 2000 275: 24752-24759. [Abstract] [Full Text] [PDF]

David B. Evans, Kenneth B. Rank, Keshab Bhattacharya, Darrell R. Thomsen, Mark E. Gurney, and Satish K. Sharma: Tau Phosphorylation at Serine 396 and Serine 404 by Human Recombinant Tau Protein Kinase II Inhibits Tau's Ability to Promote Microtubule Assembly
J. Biol. Chem. 2000 275: 24977-24983. [Abstract] [Full Text] [PDF]

Christopher M. Cabral, Priya Choudhury, Yan Liu, and Richard N. Sifers: Processing by Endoplasmic Reticulum Mannosidases Partitions a Secretion-impaired Glycoprotein into Distinct Disposal Pathways
J. Biol. Chem. 2000 275: 25015-25022. [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Joanna P. Davies and Yiannis A. Ioannou: Topological Analysis of Niemann-Pick C1 Protein Reveals That the Membrane Orientation of the Putative Sterol-sensing Domain Is Identical to Those of 3-Hydroxy-3-methylglutaryl-CoA Reductase and Sterol Regulatory Element Binding Protein Cleavage-activating Protein
J. Biol. Chem. 2000 275: 24367-24374. [Abstract] [Full Text] [PDF]

Kamini Hingorani, Attila Szebeni, and Mark O. J. Olson: Mapping the Functional Domains of Nucleolar Protein B23
J. Biol. Chem. 2000 275: 24451-24457. [Abstract] [Full Text] [PDF]

James G. Bann and Hans Peter Bächinger: Glycosylation/Hydroxylation-induced Stabilization of the Collagen Triple Helix. 4-trans-HYDROXYPROLINE IN THE Xaa POSITION CAN STABILIZE THE TRIPLE HELIX
J. Biol. Chem. 2000 275: 24466-24469. [Abstract] [Full Text] [PDF]

Richard B. Jacobsen, E. Dietlind Koch, Bettina Lange-Malecki, Martin Stocker, Janko Verhey, Ryan M. Van Wagoner, Alexandra Vyazovkina, Baldomero M. Olivera, and Heinrich Terlau: Single Amino Acid Substitutions in $kappa$ -Conotoxin PVIIA Disrupt Interaction with the Shaker K⁺ Channel
J. Biol. Chem. 2000 275: 24639-24644. [Abstract] [Full Text] [PDF]

Franklin J. Moy, Smruti A. Desai, Xinhui Wang, Elvyra J. Noronha, Qinwei Zhou, Soldano Ferrone, and Robert Powers: Analysis by NMR Spectroscopy of the Structural Homology between the Linear and the Cyclic Peptide Recognized by Anti-human Leukocyte Antigen Class I Monoclonal Antibody TP25.99*
J. Biol. Chem. 2000 275: 24679-24685. [Abstract] [Full Text] [PDF]

Kazutoyo Terada and Masataka Mori: Human DnaJ Homologs dj2 and dj3, and bag-1 Are Positive Cochaperones of hsc70
J. Biol. Chem. 2000 275: 24728-24734. [Abstract] [Full Text] [PDF]

Philip G. Board, Marjorie Coggan, Gareth Chelvanayagam, Simon Easteal, Lars S. Jermiin, Gayle K. Schulte, Dennis E. Danley, Lise R. Hoth, Matthew C. Griffor, Ajith V. Kamath, Michele H. Rosner, Boris A. Chrunyk, David E. Perregaux, Christopher A. Gabel, Kieran F. Geoghegan, and Jayvardhan Pandit: Identification, Characterization, and Crystal Structure of the Omega Class Glutathione Transferases
J. Biol. Chem. 2000 275: 24798-24806. [Abstract] [Full Text] [PDF]

Helen Ritchie, Laura C. Lawrie, Patricia W. Crombie, Michael W. Mosesson, and Nuala A. Booth: Cross-linking of Plasminogen Activator Inhibitor 2 and $alpha$ ₂-Antiplasmin to Fibrin(ogen)
J. Biol. Chem. 2000 275: 24915-24920. [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Ori Shliom, Mingdong Huang, Bruce Sachais, Alice Kuo, John W. Weisel, Chandrasekaran Nagaswami, Taher Nassar, Khalil Bdeir, Edna Hiss, Susan Gawlak, Scott Harris, Andrew Mazar, and Abd Al-Roof Higazi: Novel Interactions between Urokinase and Its Receptor
J. Biol. Chem. 2000 275: 24304-24312. [Abstract] [Full Text] [PDF]

Jane Atkins and Paul Glynn: Membrane Association of and Critical Residues in the Catalytic Domain of Human Neuropathy Target Esterase
J. Biol. Chem. 2000 275: 24477-24483. [Abstract] [Full Text] [PDF]

Dinesh Christendat, Vivian Saridakis, Akil Dharamsi, Alexei Bochkarev, Emil F. Pai, Cheryl H. Arrowsmith, and Aled M. Edwards: Crystal Structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-Epimerase from Methanobacterium thermoautotrophicum Complexed with dTDP
J. Biol. Chem. 2000 275: 24608-24612. [Abstract] [Full Text] [PDF]

Gianluca Molla, Davide Porrini, Viviana Job, Laura Motteran, Cristina Vegezzi, Stefano Campaner, Mirella S. Pilone, and Loredano Pollegioni: Role of Arginine 285 in the Active Site of Rhodotorula gracilis D-Amino Acid Oxidase. A SITE-DIRECTED MUTAGENESIS STUDY
J. Biol. Chem. 2000 275: 24715-24721. [Abstract] [Full Text] [PDF]

Xiong Liu, Hanna Brzeska, and Edward D. Korn: Functional Analysis of Tail Domains of Acanthamoeba Myosin IC by Characterization of Truncation and Deletion Mutants
J. Biol. Chem. 2000 275: 24886-24892. [Abstract] [Full Text] [PDF]

Zhi Xie, Wan-Ting Ho, and John H. Exton: Association of the N- and C-terminal Domains of Phospholipase D. CONTRIBUTION OF THE CONSERVED HKD MOTIFS TO THE INTERACTION AND THE REQUIREMENT OF THE ASSOCIATION FOR Ser/Thr PHOSPHORYLATION OF THE ENZYME
J. Biol. Chem. 2000 275: 24962-24969. [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Asish K. Saha, Alexandria J. Schwarsin, Raphael Roduit, Frédéric Massé, Virendar Kaushik, Keith Tornheim, Marc Prentki, and Neil B. Ruderman: Activation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1- $beta$ -D-ribofuranoside
J. Biol. Chem. 2000 275: 24279-24283. [Abstract] [Full Text] [PDF]

Poul Erik Jensen, Margaret Gilpin, Jürgen Knoetzel, and Henrik Vibe Scheller: The PSI-K Subunit of Photosystem I Is Involved in the Interaction between Light-harvesting Complex I and the Photosystem I Reaction Center Core
J. Biol. Chem. 2000 275: 24701-24708. [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Eric H. Holmes, Ten-Yang Yen, Scott Thomas, Rajesh Joshi, Anton Nguyen, Tracy Long, François Gallet, Abderrahman Maftah, Raymond Julien, and Bruce A. Macher: Human $alpha$ 1,3/4 Fucosyltransferases. CHARACTERIZATION OF HIGHLY CONSERVED CYSTEINE RESIDUES AND N-LINKED GLYCOSYLATION SITES
J. Biol. Chem. 2000 275: 24237-24245. [Abstract] [Full Text] [PDF]

Anita R. Patil, Celestine J. Thomas, and Avadhesha Surolia: Kinetics and the Mechanism of Interaction of the Endoplasmic Reticulum Chaperone, Calreticulin, with Monoglucosylated (Glc₁Man₉GlcNAc₂) Substrate
J. Biol. Chem. 2000 275: 24348-24356. [Abstract] [Full Text] [PDF]

Timothy M. Trask, Barbara Crippes Trask, Timothy M. Ritty, William R. Abrams, Joel Rosenbloom, and Robert P. Mecham: Interaction of Tropoelastin with the Amino-terminal Domains of Fibrillin-1 and Fibrillin-2 Suggests a Role for the Fibrillins in Elastic Fiber Assembly
J. Biol. Chem. 2000 275: 24400-24406. [Abstract] [Full Text] [PDF]

Mei Chen, Edel A. O'Toole, Matthew Muellenhoff, Elenea Medina, Nori Kasahara, and David T. Woodley: Development and Characterization of A Recombinant Truncated Type VII Collagen "Minigene". IMPLICATION FOR GENE THERAPY OF DYSTROPHIC EPIDERMOLYSIS BULLOSA
J. Biol. Chem. 2000 275: 24429-24435. [Abstract] [Full Text] [PDF]

Isabelle Flury, Abdellah Benachour, and Andreas Conzelmann: YLL031c Belongs to a Novel Family of Membrane Proteins Involved in the Transfer of Ethanolaminephosphate onto the Core Structure of Glycosylphosphatidylinositol Anchors in Yeast
J. Biol. Chem. 2000 275: 24458-24465. [Abstract] [Full Text] [PDF]

Ramachandra S. Naik, Eugene A. Davidson, and D. Channe Gowda: Developmental Stage-specific Biosynthesis of Glycosylphosphatidylinositol Anchors in Intraerythrocytic Plasmodium falciparum and Its Inhibition in a Novel Manner by Mannosamine
J. Biol. Chem. 2000 275: 24506-24511. [Abstract] [Full Text] [PDF]

John H. Patterson, Malcolm J. McConville, Ruth E. Haites, Ross L. Coppel, and Helen Billman-Jacobe: Identification of a Methyltransferase from Mycobacterium smegmatis Involved in Glycopeptidolipid Synthesis
J. Biol. Chem. 2000 275: 24900-24906. [Abstract] [Full Text] [PDF]

Ningyu Chen, Chih-Chiun Chen, and Lester F. Lau: Adhesion of Human Skin Fibroblasts to Cyr61 Is Mediated through Integrin $alpha$ ₆ $beta$ ₁ and Cell Surface Heparan Sulfate Proteoglycans
J. Biol. Chem. 2000 275: 24953-24961. [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Arun K. Das, Michael D. Uhler, and Amiya K. Hajra: Molecular Cloning and Expression of Mammalian Peroxisomal trans-2-Enoyl-coenzyme A Reductase cDNAs
J. Biol. Chem. 2000 275: 24333-24340. [Abstract] [Full Text] [PDF]

Khai Tran, Yuwei Wang, Cynthia J. DeLong, Zheng Cui, and Zemin Yao: The Assembly of Very Low Density Lipoproteins in Rat Hepatoma McA-RH7777 Cells Is Inhibited by Phospholipase A₂ Antagonists
J. Biol. Chem. 2000 275: 25023-25030. [Abstract] [Full Text] [PDF]

Membrane Transport Structure Function and Biogenesis:

Ora A. Weisz, Gregory A. Gibson, Som-Ming Leung, John Roder, and Andreas Jeromin: Overexpression of Frequenin, a Modulator of Phosphatidylinositol 4-Kinase, Inhibits Biosynthetic Delivery of an Apical Protein in Polarized Madin-Darby Canine Kidney Cells
J. Biol. Chem. 2000 275: 24341-24347. [Abstract] [Full Text] [PDF]

Dwight W. Martin and John R. Sachs: Ligands Presumed to Label High Affinity and Low Affinity ATP Binding Sites Do Not Interact in an ( $alpha$ $beta$ )₂ Diprotomer in Duck Nasal Gland Na⁺,K⁺-ATPase, nor Do the Sites Coexist in Native Enzyme
J. Biol. Chem. 2000 275: 24512-24517. [Abstract] [Full Text] [PDF]

Daniel H. Feldman, William R. Harvey, and Bruce R. Stevens: A Novel Electrogenic Amino Acid Transporter Is Activated by K⁺ or Na⁺, Is Alkaline pH-dependent, and Is Cl-independent
J. Biol. Chem. 2000 275: 24518-24526. [Abstract] [Full Text] [PDF]

Siegfried Waldegger and Thomas J. Jentsch: Functional and Structural Analysis of ClC-K Chloride Channels Involved in Renal Disease
J. Biol. Chem. 2000 275: 24527-24533. [Abstract] [Full Text] [PDF]

Wataru Nunomura, Yuichi Takakuwa, Marilyn Parra, John Conboy, and Narla Mohandas: Regulation of Protein 4.1R, p55, and Glycophorin C Ternary Complex in Human Erythrocyte Membrane
J. Biol. Chem. 2000 275: 24540-24546. [Abstract] [Full Text] [PDF]

Michael F. Romero, Darin Henry, Stephanie Nelson, Peter J. Harte, Alison K. Dillon, and Christopher M. Sciortino: Cloning and Characterization of a Na⁺-driven Anion Exchanger (NDAE1). A NEW BICARBONATE TRANSPORTER
J. Biol. Chem. 2000 275: 24552-24559. [Abstract] [Full Text] [PDF]

Stephanie C. Stotz, Jawed Hamid, Renee L. Spaetgens, Scott E. Jarvis, and Gerald W. Zamponi: Fast Inactivation of Voltage-dependent Calcium Channels. A HINGED-LID MECHANISM?
J. Biol. Chem. 2000 275: 24575-24582. [Abstract] [Full Text] [PDF]

Simon Hoffenberg, X. Liu, Lydia Nikolova, Hassan S. Hall, Wenping Dai, Robert E. Baughn, Burton F. Dickey, M. Alejandro Barbieri, Alejando Aballay, Philip D. Stahl, and Brian J. Knoll: A Novel Membrane-anchored Rab5 Interacting Protein Required for Homotypic Endosome Fusion
J. Biol. Chem. 2000 275: 24661-24669. [Abstract] [Full Text] [PDF]

Qing Zhao and Carlos R. Morales: Identification of a Novel Sequence Involved in Lysosomal Sorting of the Sphingolipid Activator Protein Prosaposin
J. Biol. Chem. 2000 275: 24829-24839. [Abstract] [Full Text] [PDF]

Vesna Dapic and Donald Oliver: Distinct Membrane Binding Properties of N- and C-terminal Domains of Escherichia coli SecA ATPase
J. Biol. Chem. 2000 275: 25000-25007. [Abstract] [Full Text] [PDF]

Ina L. Urbatsch, Khursheed Gimi, Susan Wilke-Mounts, and Alan E. Senior: Conserved Walker A Ser Residues in the Catalytic Sites of P-glycoprotein Are Critical for Catalysis and Involved Primarily at the Transition State Step
J. Biol. Chem. 2000 275: 25031-25038. [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Ying Lin, Hyangkyu Lee, Anders H. Berg, Michael P. Lisanti, Lawrence Shapiro, and Philipp E. Scherer: The Lipopolysaccharide-activated Toll-like Receptor (TLR)-4 Induces Synthesis of the Closely Related Receptor TLR-2 in Adipocytes
J. Biol. Chem. 2000 275: 24255-24263. [Abstract] [Full Text] [PDF]

Michael A. Zimmer, Joseph Tiu, Marissa A. Collins, and George W. Ordal: Selective Methylation Changes on the Bacillus subtilis Chemotaxis Receptor McpB Promote Adaptation
J. Biol. Chem. 2000 275: 24264-24272. [Abstract] [Full Text] [PDF]

Martin Sattler, Shalini Verma, Gautam Shrikhande, Christopher H. Byrne, Yuri B. Pride, Thomas Winkler, Edward A. Greenfield, Ravi Salgia, and James D. Griffin: The BCR/ABL Tyrosine Kinase Induces Production of Reactive Oxygen Species in Hematopoietic Cells
J. Biol. Chem. 2000 275: 24273-24278. [Abstract] [Full Text] [PDF]

Takuya Kobayashi, Fumitaka Ushikubi, and Shuh Narumiya: Amino Acid Residues Conferring Ligand Binding Properties of Prostaglandin I and Prostaglandin D Receptors. IDENTIFICATION BY SITE-DIRECTED MUTAGENESIS
J. Biol. Chem. 2000 275: 24294-24303. [Abstract] [Full Text] [PDF]

Michelle M. Hill, Lisa M. Connolly, Richard J. Simpson, and David E. James: Differential Protein Phosphorylation in 3T3-L1 Adipocytes in Response to Insulin Versus Platelet-derived Growth Factor. NO EVIDENCE FOR A PHOSPHATIDYLINOSITIDE 3-KINASE-INDEPENDENT PATHWAY IN INSULIN SIGNALING
J. Biol. Chem. 2000 275: 24313-24320. [Abstract] [Full Text] [PDF]

Harald Wajant, Elvira Haas, Ralph Schwenzer, Frank Mühlenbeck, Sebastian Kreuz, Gisela Schubert, Matthias Grell, Craig Smith, and Peter Scheurich: Inhibition of Death Receptor-mediated Gene Induction by a Cycloheximide-sensitive Factor Occurs at the Level of or Upstream of Fas-associated Death Domain Protein (FADD)
J. Biol. Chem. 2000 275: 24357-24366. [Abstract] [Full Text] [PDF]

Angel G. Martin and Manuel Fresno: Tumor Necrosis Factor- $alpha$ Activation of NF- $kappa$ B Requires the Phosphorylation of Ser-471 in the Transactivation Domain of c-Rel
J. Biol. Chem. 2000 275: 24383-24391. [Abstract] [Full Text] [PDF]

Kouichi Ariyoshi, Tetsuya Nosaka, Koji Yamada, Mayumi Onishi, Yoshitomo Oka, Atsushi Miyajima, and Toshio Kitamura: Constitutive Activation of STAT5 by a Point Mutation in the SH2 Domain
J. Biol. Chem. 2000 275: 24407-24413. [Abstract] [Full Text] [PDF]

Jouni Vesa, Alex Krüttgen, and Eric M. Shooter: p75 Reduces TrkB Tyrosine Autophosphorylation in Response to Brain-derived Neurotrophic Factor and Neurotrophin 4/5
J. Biol. Chem. 2000 275: 24414-24420. [Abstract] [Full Text] [PDF]

Weiyong Sun, Sylvie Vincent, Jeffrey Settleman, and Gary L. Johnson: MEK Kinase 2 Binds and Activates Protein Kinase C-related Kinase 2. BIFURCATION OF KINASE REGULATORY PATHWAYS AT THE LEVEL OF AN MAPK KINASE KINASE
J. Biol. Chem. 2000 275: 24421-24428. [Abstract] [Full Text] [PDF]

Rong Zhang, Zhongjia Tan, and Peng Liang: Identification of a Novel Ligand-Receptor Pair Constitutively Activated by ras Oncogenes
J. Biol. Chem. 2000 275: 24436-24443. [Abstract] [Full Text] [PDF]

Chong-Shan Shi, Srikumar Sinnarajah, Hyeseon Cho, Tohru Kozasa, and John H. Kehrl: G₁₃ $alpha$ -mediated PYK2 Activation. PYK2 IS A MEDIATOR OF G₁₃ $alpha$ -INDUCED SERUM RESPONSE ELEMENT-DEPENDENT TRANSCRIPTION
J. Biol. Chem. 2000 275: 24470-24476. [Abstract] [Full Text] [PDF]

Paul C. Brandt and Thomas C. Vanaman: Elevated Glucocorticoid Receptor Transactivation and Down-regulation of $alpha$ ₁ Integrin Are Associated with Loss of Plasma Membrane Ca²⁺-ATPase Isoform 1
J. Biol. Chem. 2000 275: 24534-24539. [Abstract] [Full Text] [PDF]

Oliver Dienz, Steffen P. Hehner, Wulf Dröge, and M. Lienhard Schmitz: Synergistic Activation of NF- $kappa$ B by Functional Cooperation between Vav and PKC $theta$ in T Lymphocytes
J. Biol. Chem. 2000 275: 24547-24551. [Abstract] [Full Text] [PDF]

Duo-Qi Zheng, Amy S. Woodard, Giovanni Tallini, and Lucia R. Languino: Substrate Specificity of $alpha$ _v $beta$ ₃ Integrin-mediated Cell Migration and Phosphatidylinositol 3-Kinase/AKT Pathway Activation
J. Biol. Chem. 2000 275: 24565-24574. [Abstract] [Full Text] [PDF]

Qing Xu, Yan-Shan Ji, and John F. Schmedtje, Jr.: Sp1 Increases Expression of Cyclooxygenase-2 in Hypoxic Vascular Endothelium. IMPLICATIONS FOR THE MECHANISMS OF AORTIC ANEURYSM AND HEART FAILURE
J. Biol. Chem. 2000 275: 24583-24589. [Abstract] [Full Text] [PDF]

Teresa A. Bennett, Diane C. Maestas, and Eric R. Prossnitz: Arrestin Binding to the G Protein-coupled N-Formyl Peptide Receptor Is Regulated by the Conserved "DRY" Sequence
J. Biol. Chem. 2000 275: 24590-24594. [Abstract] [Full Text] [PDF]

Peter Storz, Angelika Hausser, Gisela Link, Jürgen Dedio, Berhane Ghebrehiwet, Klaus Pfizenmaier, and Franz-Josef Johannes: Protein Kinase C µ Is Regulated by the Multifunctional Chaperon Protein p32
J. Biol. Chem. 2000 275: 24601-24607. [Abstract] [Full Text] [PDF]

Anthony Nichols, Montserrat Camps, Corine Gillieron, Christian Chabert, Anne Brunet, Julie Wilsbacher, Melanie Cobb, Jacques Pouyssegur, Jeffrey P. Shaw, and Steve Arkinstall: Substrate Recognition Domains within Extracellular Signal-regulated Kinase Mediate Binding and Catalytic Activation of Mitogen-activated Protein Kinase Phosphatase-3
J. Biol. Chem. 2000 275: 24613-24621. [Abstract] [Full Text] [PDF]

Lars Lundin, Helena Larsson, Johan Kreuger, Shigeru Kanda, Ulf Lindahl, Markku Salmivirta, and Lena Claesson-Welsh: Selectively Desulfated Heparin Inhibits Fibroblast Growth Factor-induced Mitogenicity and Angiogenesis
J. Biol. Chem. 2000 275: 24653-24660. [Abstract] [Full Text] [PDF]

Silke Lüschen, Sandra Ussat, Gudrun Scherer, Dieter Kabelitz, and Sabine Adam-Klages: Sensitization to Death Receptor Cytotoxicity by Inhibition of Fas-associated Death Domain Protein (FADD)/Caspase Signaling. REQUIREMENT OF CELL CYCLE PROGRESSION
J. Biol. Chem. 2000 275: 24670-24678. [Abstract] [Full Text] [PDF]

Adolfo Saiardi, James J. Caffrey, Solomon H. Snyder, and Stephen B. Shears: The Inositol Hexakisphosphate Kinase Family. CATALYTIC FLEXIBILITY AND FUNCTION IN YEAST VACUOLE BIOGENESIS
J. Biol. Chem. 2000 275: 24686-24692. [Abstract] [Full Text] [PDF]

Heng-Yin Yang, Binhua P. Zhou, Mien-Chie Hung, and Mong-Hong Lee: Oncogenic Signals of HER-2/neu in Regulating the Stability of the Cyclin-dependent Kinase Inhibitor p27
J. Biol. Chem. 2000 275: 24735-24739. [Abstract] [Full Text] [PDF]

Yasuhito Shirai, Satoko Segawa, Masamitsu Kuriyama, Kaoru Goto, Norio Sakai, and Naoaki Saito: Subtype-specific Translocation of Diacylglycerol Kinase $alpha$ and $gamma$ and Its Correlation with Protein Kinase C
J. Biol. Chem. 2000 275: 24760-24766. [Abstract] [Full Text] [PDF]

Olga Potapova, Myriam Gorospe, Frédéric Bost, Nicholas M. Dean, William A. Gaarde, Dan Mercola, and Nikki J. Holbrook: c-Jun N-terminal Kinase Is Essential for Growth of Human T98G Glioblastoma Cells
J. Biol. Chem. 2000 275: 24767-24775. [Abstract] [Full Text] [PDF]

Marcela Escalante, Jody Courtney, Wai Gong Chin, Kenneth K. Teng, Jong-Il Kim, J. Eduardo Fajardo, Bruce J. Mayer, Barbara L. Hempstead, and Raymond B. Birge: Phosphorylation of c-Crk II on the Negative Regulatory Tyr²²² Mediates Nerve Growth Factor-induced Cell Spreading and Morphogenesis
J. Biol. Chem. 2000 275: 24787-24797. [Abstract] [Full Text] [PDF]

Keng Meng Khoo, Myung-Kwan Han, Jin Bong Park, Soo Wan Chae, Uh-Hyun Kim, Hon Cheung Lee, Boon Huat Bay, and Chan Fong Chang: Localization of the Cyclic ADP-ribose-dependent Calcium Signaling Pathway in Hepatocyte Nucleus
J. Biol. Chem. 2000 275: 24807-24817. [Abstract] [Full Text] [PDF]

Mariusz Stasiolek, Vitaliy Gavrilyuk, Anthony Sharp, Peter Horvath, Kris Selmaj, and Douglas L. Feinstein: Inhibitory and Stimulatory Effects of Lactacystin on Expression of Nitric Oxide Synthase Type 2 in Brain Glial Cells. THE ROLE OF I $kappa$ B- $beta$
J. Biol. Chem. 2000 275: 24847-24856. [Abstract] [Full Text] [PDF]

D. Scott Witherow, Qiang Wang, Konstatin Levay, Jorge L. Cabrera, Jeannie Chen, Gary B. Willars, and Vladlen Z. Slepak: Complexes of the G Protein Subunit G $beta$ ₅ with the Regulators of G Protein Signaling RGS7 and RGS9. CHARACTERIZATION IN NATIVE TISSUES AND IN TRANSFECTED CELLS
J. Biol. Chem. 2000 275: 24872-24880. [Abstract] [Full Text] [PDF]

Chuan Yin Liu, Martin Schröder, and Randal J. Kaufman: Ligand-independent Dimerization Activates the Stress Response Kinases IRE1 and PERK in the Lumen of the Endoplasmic Reticulum
J. Biol. Chem. 2000 275: 24881-24885. [Abstract] [Full Text] [PDF]

Ping Xie, Darren D. Browning, Nissim Hay, Nigel Mackman, and Richard D. Ye: Activation of NF- $kappa$ B by Bradykinin through a G $alpha$ _q- and G $beta$ $gamma$ -dependent Pathway That Involves Phosphoinositide 3-Kinase and Akt
J. Biol. Chem. 2000 275: 24907-24914. [Abstract] [Full Text] [PDF]

Yi Zhang, James Turkson, Christin Carter-Su, Thomas Smithgall, Alexander Levitzki, Alan Kraker, John J. Krolewski, Peter Medveczky, and Richard Jove: Activation of Stat3 in v-Src-transformed Fibroblasts Requires Cooperation of Jak1 Kinase Activity
J. Biol. Chem. 2000 275: 24935-24944. [Abstract] [Full Text] [PDF]

Koji Yoshida, Yoshihiro Yamashita, Akira Miyazato, Ken-ichi Ohya, Akira Kitanaka, Uichi Ikeda, Kazuyuki Shimada, Takeo Yamanaka, Keiya Ozawa, and Hiroyuki Mano: Mediation by the Protein-tyrosine Kinase Tec of Signaling between the B Cell Antigen Receptor and Dok-1
J. Biol. Chem. 2000 275: 24945-24952. [Abstract] [Full Text] [PDF]

Yi Zhang, Soek Ying Neo, Jiahuai Han, and Sheng-Cai Lin: Dimerization Choices Control the Ability of Axin and Dishevelled to Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase
J. Biol. Chem. 2000 275: 25008-25014. [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Chao Liu, Eva Gelius, Gang Liu, Håkan Steiner, and Roman Dziarski: Mammalian Peptidoglycan Recognition Protein Binds Peptidoglycan with High Affinity, Is Expressed in Neutrophils, and Inhibits Bacterial Growth
J. Biol. Chem. 2000 275: 24490-24499. [Abstract] [Full Text] [PDF]

Jeremy R. Graff, Bruce W. Konicek, Ann M. McNulty, Zejing Wang, Keith Houck, Sheryl Allen, Jonathan D. Paul, Ahed Hbaiu, Robin G. Goode, George E. Sandusky, Robert L. Vessella, and Blake Lee Neubauer: Increased AKT Activity Contributes to Prostate Cancer Progression by Dramatically Accelerating Prostate Tumor Growth and Diminishing p27^Kip1 Expression
J. Biol. Chem. 2000 275: 24500-24505. [Abstract] [Full Text] [PDF]

David J. Onley, C. Graham Knight, Danny S. Tuckwell, Michael J. Barnes, and Richard W. Farndale: Micromolar Ca²⁺ Concentrations Are Essential for Mg²⁺-dependent Binding of Collagen by the Integrin $alpha$ ₂ $beta$ ₁ in Human Platelets
J. Biol. Chem. 2000 275: 24560-24564. [Abstract] [Full Text] [PDF]

Jean-Michel Gaullier, Eva Rønning, David J. Gillooly, and Harald Stenmark: Interaction of the EEA1 FYVE Finger with Phosphatidylinositol 3-Phosphate and Early Endosomes. ROLE OF CONSERVED RESIDUES
J. Biol. Chem. 2000 275: 24595-24600. [Abstract] [Full Text] [PDF]

Michael Goldberg, Courtney Peshkovsky, Ashkan Shifteh, and Qais Al-Awqati: µ-Protocadherin, a Novel Developmentally Regulated Protocadherin with Mucin-like Domains
J. Biol. Chem. 2000 275: 24622-24629. [Abstract] [Full Text] [PDF]

Yong-Sheng Xu, Marc Kantorow, Janine Davis, and Joram Piatigorsky: Evidence for Gelsolin as a Corneal Crystallin in Zebrafish
J. Biol. Chem. 2000 275: 24645-24652. [Abstract] [Full Text] [PDF]

Adam L. Greene, M. Jane Lalli, Yong Ji, Gopal Jegadeesh Babu, Ingrid Grupp, Mark Sussman, and Muthu Periasamy: Overexpression of SERCA2b in the Heart Leads to an Increase in Sarcoplasmic Reticulum Calcium Transport Function and Increased Cardiac Contractility
J. Biol. Chem. 2000 275: 24722-24727. [Abstract] [Full Text] [PDF]

Vitaly A. Polunovsky, Anne-Claude Gingras, Nahum Sonenberg, Mark Peterson, Annie Tan, Jeffrey B. Rubins, J. Carlos Manivel, and Peter B. Bitterman: Translational Control of the Antiapoptotic Function of Ras
J. Biol. Chem. 2000 275: 24776-24780. [Abstract] [Full Text] [PDF]

Lucia Driller, Raymund J. Wellinger, Michel Larrivée, Elisabeth Kremmer, Sigrun Jaklin, and Heidi M. Feldmann: A Short C-terminal Domain of Yku70p Is Essential for Telomere Maintenance
J. Biol. Chem. 2000 275: 24921-24927. [Abstract] [Full Text] [PDF]

Min Yu, Robert H. A. Haslam, and David B. Haslam: HEDJ, an Hsp40 Co-chaperone Localized to the Endoplasmic Reticulum of Human Cells
J. Biol. Chem. 2000 275: 24984-24992. [Abstract] [Full Text] [PDF]

Joaquín Royo, Elisa Gómez, and Gregorio Hueros: A Maize Homologue of the Bacterial CMP-3-Deoxy-D-manno-2-octulosonate (KDO) Synthetases. SIMILAR PATHWAYS OPERATE IN PLANTS AND BACTERIA FOR THE ACTIVATION OF KDO PRIOR TO ITS INCORPORATION INTO OUTER CELLULAR ENVELOPES
J. Biol. Chem. 2000 275: 24993-24999. [Abstract] [Full Text] [PDF]

Xiao-Mai Zhou, Yimao Liu, Gillian Payne, Robert J. Lutz, and Thomas Chittenden: Growth Factors Inactivate the Cell Death Promoter BAD by Phosphorylation of Its BH3 Domain on Ser¹⁵⁵
J. Biol. Chem. 2000 275: 25046-25051. [Abstract] [Full Text] [PDF]

Additions and Corrections:

Tatsuya Matsuo, Jimmy K. Stauffer, Robert L. Walker, Paul Meltzer, and Carol J. Thiele: Structure and promoter analysis of the human unc-33-like phosphoprotein gene: E-box required for maximal expression in neuroblastoma and myoblasts.
J. Biol. Chem. 2000 275: 25052. [Full Text] [PDF]

Khaled A. H. Abo-Hashema, Max H. Cake, Glen W. Power, and Doug Clarke: Evidence for triacylglycerol synthesis in the lumen of microsomes via a lipolysis-esterification pathway involving carnitine acyltransferases.
J. Biol. Chem. 2000 275: 25054. [Full Text] [PDF]

Kristopher Josephson, Ruth DiGiacomo, Stephen R. Indelicato, Abiye H. Iyo, T. L. Nagabhushan, Matthew H. Parker, and Mark R. Walter: Design and analysis of an engineered human interleukin-10 monomer.
J. Biol. Chem. 2000 275: 25054. [Full Text] [PDF]