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Table of Contents: Nov 3 2000; 275 (44)   [Index by Author]  [Cover Figure and Caption]
       Minireviews
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       Protein Synthesis Post-Translation Modification and Degradation
       Genomics Proteomics and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Minireviews:

Domenico Gatti, Bharati Mitra, and Barry P. Rosen
Escherichia coli Soft Metal Ion-translocating ATPases
J. Biol. Chem. 2000 275: 34009-34012. Published as JBC Papers in Press 10.1074/jbc.R000012200 [Full Text] [PDF]  


Accelerated Publications:

Kazuaki Takaku, Masahiro Sonoshita, Nobuya Sasaki, Naonori Uozumi, Yoshiko Doi, Takao Shimizu, and Makoto M. Taketo
Suppression of Intestinal Polyposis in ApcDelta 716 Knockout Mice by an Additional Mutation in the Cytosolic Phospholipase A2 Gene
J. Biol. Chem. 2000 275: 34013-34016. Published as JBC Papers in Press 10.1074/jbc.C000585200 [Abstract] [Full Text] [PDF]  

Michael M. Lai, Hongbo R. Luo, Patrick E. Burnett, Jenny J. Hong, and Solomon H. Snyder
The Calcineurin-binding Protein Cain Is a Negative Regulator of Synaptic Vesicle Endocytosis
J. Biol. Chem. 2000 275: 34017-34020. Published as JBC Papers in Press 10.1074/jbc.C000429200 [Abstract] [Full Text] [PDF]  

Erik D. Foehr, Jan Bohuslav, Lin-Feng Chen, Carlos DeNoronha, Romas Geleziunas, Xin Lin, Alison O'Mahony, and Warner C. Greene
The NF-kappa B-inducing Kinase Induces PC12 Cell Differentiation and Prevents Apoptosis
J. Biol. Chem. 2000 275: 34021-34024. Published as JBC Papers in Press 10.1074/jbc.C000507200 [Abstract] [Full Text] [PDF]  

Michael J. MacDonald and Leonard A. Fahien
Glutamate Is Not a Messenger in Insulin Secretion
J. Biol. Chem. 2000 275: 34025-34027. Published as JBC Papers in Press 10.1074/jbc.C000411200 [Abstract] [Full Text] [PDF]  


DNA: Replication Repair and Recombination:

Frank P. Leu, Manju M. Hingorani, Jennifer Turner, and Mike O'Donnell
The delta Subunit of DNA Polymerase III Holoenzyme Serves as a Sliding Clamp Unloader in Escherichia coli
J. Biol. Chem. 2000 275: 34609-34618. Published as JBC Papers in Press 10.1074/jbc.M005495200 [Abstract] [Full Text] [PDF]  

Xiaojun Li and Kenneth J. Marians
Two Distinct Triggers for Cycling of the Lagging Strand Polymerase at the Replication Fork
J. Biol. Chem. 2000 275: 34757-34765. Published as JBC Papers in Press 10.1074/jbc.M006556200 [Abstract] [Full Text] [PDF]  

Hiroshi Hiasa and Molly E. Shea
DNA Gyrase-mediated Wrapping of the DNA Strand Is Required for the Replication Fork Arrest by the DNA Gyrase-Quinolone-DNA Ternary Complex
J. Biol. Chem. 2000 275: 34780-34786. Published as JBC Papers in Press 10.1074/jbc.M001608200 [Abstract] [Full Text] [PDF]  

Kyung-Jong Lee, Juren Huang, Yoshihiko Takeda, and William S. Dynan
DNA Ligase IV and XRCC4 Form a Stable Mixed Tetramer That Functions Synergistically with Other Repair Factors in a Cell-free End-joining System
J. Biol. Chem. 2000 275: 34787-34796. Published as JBC Papers in Press 10.1074/jbc.M004011200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Rossana De Leo, Stefania Miccadei, Enrico Zammarchi, and Donato Civitareale
Role for p300 in Pax 8 Induction of Thyroperoxidase Gene Expression
J. Biol. Chem. 2000 275: 34100-34105. Published as JBC Papers in Press 10.1074/jbc.M003043200 [Abstract] [Full Text] [PDF]  

Nathalie Delesque-Touchard, Soo-Hee Park, and David J. Waxman
Synergistic Action of Hepatocyte Nuclear Factors 3 and 6 on CYP2C12 Gene Expression and Suppression by Growth Hormone-activated STAT5b. PROPOSED MODEL FOR FEMALE-SPECIFIC EXPRESSION OF CYP2C12 IN ADULT RAT LIVER
J. Biol. Chem. 2000 275: 34173-34182. Published as JBC Papers in Press 10.1074/jbc.M004027200 [Abstract] [Full Text] [PDF]  

Kishor K. Bhakat and Sankar Mitra
Regulation of the Human O6-Methylguanine-DNA Methyltransferase Gene by Transcriptional Coactivators cAMP Response Element-binding Protein-binding Protein and p300
J. Biol. Chem. 2000 275: 34197-34204. Published as JBC Papers in Press 10.1074/jbc.M005447200 [Abstract] [Full Text] [PDF]  

Hirotaka Watada, Raghavendra G. Mirmira, Joey Leung, and Michael S. German
Transcriptional and Translational Regulation of beta -Cell Differentiation Factor Nkx6.1
J. Biol. Chem. 2000 275: 34224-34230. Published as JBC Papers in Press 10.1074/jbc.M004981200 [Abstract] [Full Text] [PDF]  

Monica M. Montano, Bryan M. Wittmann, and Nicole R. Bianco
Identification and Characterization of a Novel Factor That Regulates Quinone Reductase Gene Transcriptional Activity
J. Biol. Chem. 2000 275: 34306-34313. Published as JBC Papers in Press 10.1074/jbc.M003880200 [Abstract] [Full Text] [PDF]  

Jing Zhang, Natarajan Tamilarasu, Seongwoo Hwang, Mitchell E. Garber, Ikramul Huq, Katherine A. Jones, and Tariq M. Rana
HIV-1 TAR RNA Enhances the Interaction between Tat and Cyclin T1
J. Biol. Chem. 2000 275: 34314-34319. Published as JBC Papers in Press 10.1074/jbc.M006804200 [Abstract] [Full Text] [PDF]  

Anna Polesskaya, Arnaud Duquet, Irina Naguibneva, Christoph Weise, Arlette Vervisch, Eyal Bengal, Ferdinand Hucho, Philippe Robin, and Annick Harel-Bellan
CREB-binding Protein/p300 Activates MyoD by Acetylation
J. Biol. Chem. 2000 275: 34359-34364. Published as JBC Papers in Press 10.1074/jbc.M003815200 [Abstract] [Full Text] [PDF]  

Alice Hudder and Rudolf Werner
Analysis of a Charcot-Marie-Tooth Disease Mutation Reveals an Essential Internal Ribosome Entry Site Element in the Connexin-32 Gene
J. Biol. Chem. 2000 275: 34586-34591. Published as JBC Papers in Press 10.1074/jbc.M005199200 [Abstract] [Full Text] [PDF]  

Xiaofeng Yu and Sherman M. Weissman
Characterization of the Promoter of Human Leukocyte-specific Transcript 1. A SMALL GENE WITH A COMPLEX PATTERN OF ALTERNATIVE TRANSCRIPTS
J. Biol. Chem. 2000 275: 34597-34608. Published as JBC Papers in Press 10.1074/jbc.M004700200 [Abstract] [Full Text] [PDF]  

Kouichi Tamura, Yuqing E. Chen, Marco Lopez-Ilasaca, Laurent Daviet, Nobuko Tamura, Tomoaki Ishigami, Masahiro Akishita, Izumi Takasaki, Yasuo Tokita, Richard E. Pratt, Masatsugu Horiuchi, Victor J. Dzau, and Satoshi Umemura
Molecular Mechanism of Fibronectin Gene Activation by Cyclic Stretch in Vascular Smooth Muscle Cells
J. Biol. Chem. 2000 275: 34619-34627. Published as JBC Papers in Press 10.1074/jbc.M004421200 [Abstract] [Full Text] [PDF]  

Judith A. Enyeart, Lin Xu, and John J. Enyeart
A Bovine Adrenocortical Kv1.4 K+ Channel Whose Expression Is Potently Inhibited by ACTH
J. Biol. Chem. 2000 275: 34640-34649. Published as JBC Papers in Press 10.1074/jbc.M004214200 [Abstract] [Full Text] [PDF]  

C. Susan Mintz-Weber and Judith P. Johnson
Identification of the Elements Regulating the Expression of the Cell Adhesion Molecule MCAM/MUC18. LOSS OF AP-2 IS NOT REQUIRED FOR MCAM EXPRESSION IN MELANOMA CELL LINES
J. Biol. Chem. 2000 275: 34672-34680. Published as JBC Papers in Press 10.1074/jbc.M003812200 [Abstract] [Full Text] [PDF]  

S. Joshua Langmade, Rudravajhala Ravindra, Patrick J. Daniels, and Glen K. Andrews
The Transcription Factor MTF-1 Mediates Metal Regulation of the Mouse ZnT1 Gene
J. Biol. Chem. 2000 275: 34803-34809. Published as JBC Papers in Press 10.1074/jbc.M007339200 [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

Eduardo Silles, María J. Mazón, Kris Gevaert, Marc Goethals, Joel Vandekerckhove, Regina Leber, and Ignacio V. Sandoval
Targeting of Aminopeptidase I to the Yeast Vacuole Is Mediated by Ssa1p, a Cytosolic Member of the 70-kDa Stress Protein Family
J. Biol. Chem. 2000 275: 34054-34059. Published as JBC Papers in Press 10.1074/jbc.M003514200 [Abstract] [Full Text] [PDF]  

Dietmar Seiffert, Jodi D. Bradley, Cynthia M. Rominger, David H. Rominger, Fude Yang, Jere E. Meredith, Jr., Qian Wang, Arthur H. Roach, Lorin A. Thompson, Susan M. Spitz, Jeffrey N. Higaki, Shimoga R. Prakash, Andrew P. Combs, Robert A. Copeland, Stephen P. Arneric, Paul R. Hartig, David W. Robertson, Barbara Cordell, Andrew M. Stern, Richard E. Olson, and Robert Zaczek
Presenilin-1 and -2 Are Molecular Targets for gamma -Secretase Inhibitors
J. Biol. Chem. 2000 275: 34086-34091. Published as JBC Papers in Press 10.1074/jbc.M005430200 [Abstract] [Full Text] [PDF]  

Jonathan K. Tyzack, Xuemin Wang, Graham J. Belsham, and Christopher G. Proud
ABC50 Interacts with Eukaryotic Initiation Factor 2 and Associates with the Ribosome in an ATP-dependent Manner
J. Biol. Chem. 2000 275: 34131-34139. Published as JBC Papers in Press 10.1074/jbc.M002868200 [Abstract] [Full Text] [PDF]  

Adil Anwar, Naushad Ali, Rasheeda Tanveer, and Aleem Siddiqui
Demonstration of Functional Requirement of Polypyrimidine Tract-binding Protein by SELEX RNA during Hepatitis C Virus Internal Ribosome Entry Site-mediated Translation Initiation
J. Biol. Chem. 2000 275: 34231-34235. Published as JBC Papers in Press 10.1074/jbc.M006343200 [Abstract] [Full Text] [PDF]  

Anselme L. Perrier, Xavier Cousin, Nicola Boschetti, Robert Haas, Jean-Marc Chatel, Suzanne Bon, William L. Roberts, Samuel R. Pickett, Jean Massoulié, Terrone L. Rosenberry, and Eric Krejci
Two Distinct Proteins Are Associated with Tetrameric Acetylcholinesterase on the Cell Surface
J. Biol. Chem. 2000 275: 34260-34265. Published as JBC Papers in Press 10.1074/jbc.M004289200 [Abstract] [Full Text] [PDF]  


Genomics Proteomics and Bioinformatics:

Robert A. Koza, Susanna M. Hohmann, Carmen Guerra, Martin Rossmeisl, and Leslie P. Kozak
Synergistic Gene Interactions Control the Induction of the Mitochondrial Uncoupling Protein (Ucp1) Gene in White Fat Tissue
J. Biol. Chem. 2000 275: 34486-34492. Published as JBC Papers in Press 10.1074/jbc.M002136200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Christian Mayr, Klaus Richter, Hauke Lilie, and Johannes Buchner
Cpr6 and Cpr7, Two Closely Related Hsp90-associated Immunophilins from Saccharomyces cerevisiae, Differ in Their Functional Properties
J. Biol. Chem. 2000 275: 34140-34146. Published as JBC Papers in Press 10.1074/jbc.M005251200 [Abstract] [Full Text] [PDF]  

Kausik Ray and Benjamin C. Hauschild
Cys-140 Is Critical for Metabotropic Glutamate Receptor-1 Dimerization
J. Biol. Chem. 2000 275: 34245-34251. Published as JBC Papers in Press 10.1074/jbc.M005581200 [Abstract] [Full Text] [PDF]  

Euijung Jo, JoAnne McLaurin, Christopher M. Yip, Peter St. George-Hyslop, and Paul E. Fraser
alpha -Synuclein Membrane Interactions and Lipid Specificity
J. Biol. Chem. 2000 275: 34328-34334. Published as JBC Papers in Press 10.1074/jbc.M004345200 [Abstract] [Full Text] [PDF]  

Richard J. Perrin, Wendy S. Woods, David F. Clayton, and Julia M. George
Interaction of Human alpha -Synuclein and Parkinson's Disease Variants with Phospholipids. STRUCTURAL ANALYSIS USING SITE-DIRECTED MUTAGENESIS
J. Biol. Chem. 2000 275: 34393-34398. Published as JBC Papers in Press 10.1074/jbc.M004851200 [Abstract] [Full Text] [PDF]  

Matthias Oleszewski, Paul Gutwein, Wilhelm von der Lieth, Uwe Rauch, and Peter Altevogt
Characterization of the L1-Neurocan-binding Site. IMPLICATIONS FOR L1-L1 HOMOPHILIC BINDING
J. Biol. Chem. 2000 275: 34478-34485. Published as JBC Papers in Press 10.1074/jbc.M004147200 [Abstract] [Full Text] [PDF]  

Min Yao, T. Ose, Hiroshi Sugimoto, Atsushi Horiuchi, Atsushi Nakagawa, Soichi Wakatsuki, Daisuke Yokoi, Toyotaka Murakami, Mamoru Honma, and Isao Tanaka
Crystal Structure of 1-Aminocyclopropane-1-carboxylate Deaminase from Hansenula saturnus
J. Biol. Chem. 2000 275: 34557-34565. Published as JBC Papers in Press 10.1074/jbc.M004681200 [Abstract] [Full Text] [PDF]  

Anja Leona Biere, Stephen J. Wood, Jette Wypych, Shirley Steavenson, Yijia Jiang, Dan Anafi, Frederick W. Jacobsen, Mark A. Jarosinski, Gay-May Wu, Jean-Claude Louis, Francis Martin, Linda O. Narhi, and Martin Citron
Parkinson's Disease-associated alpha -Synuclein Is More Fibrillogenic than beta - and gamma -Synuclein and Cannot Cross-seed Its Homologs
J. Biol. Chem. 2000 275: 34574-34579. Published as JBC Papers in Press 10.1074/jbc.M005514200 [Abstract] [Full Text] [PDF]  

Jonathan R. Moll, Michelle Olive, and Charles Vinson
Attractive Interhelical Electrostatic Interactions in the Proline- and Acidic-rich Region (PAR) Leucine Zipper Subfamily Preclude Heterodimerization with Other Basic Leucine Zipper Subfamilies
J. Biol. Chem. 2000 275: 34826-34832. Published as JBC Papers in Press 10.1074/jbc.M004545200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Carrie A. Hicks-Berger, Brian Paul Chadwick, Anna-Maria Frischauf, and Terence L. Kirley
Expression and Characterization of Soluble and Membrane-bound Human Nucleoside Triphosphate Diphosphohydrolase 6 (CD39L2)
J. Biol. Chem. 2000 275: 34041-34045. Published as JBC Papers in Press 10.1074/jbc.M004723200 [Abstract] [Full Text] [PDF]  

Maria Norlin, Ulla Andersson, Ingemar Björkhem, and Kjell Wikvall
Oxysterol 7alpha -Hydroxylase Activity by Cholesterol 7alpha -Hydroxylase (CYP7A)
J. Biol. Chem. 2000 275: 34046-34053. Published as JBC Papers in Press 10.1074/jbc.M002663200 [Abstract] [Full Text] [PDF]  

Ying Jiang, Weijun Qian, John W. Hawes, and James P. Walsh
A Domain with Homology to Neuronal Calcium Sensors Is Required for Calcium-dependent Activation of Diacylglycerol Kinase alpha
J. Biol. Chem. 2000 275: 34092-34099. Published as JBC Papers in Press 10.1074/jbc.M004914200 [Abstract] [Full Text] [PDF]  

Oded Kleifeld, Philippe E. Van den Steen, Anatoly Frenkel, Feng Cheng, Hua Liang Jiang, Ghislain Opdenakker, and Irit Sagi
Structural Characterization of the Catalytic Active Site in the Latent and Active Natural Gelatinase B from Human Neutrophils
J. Biol. Chem. 2000 275: 34335-34343. Published as JBC Papers in Press 10.1074/jbc.M005714200 [Abstract] [Full Text] [PDF]  

Yi Liu, Luke Koenigs Lightning, Hong-wei Huang, Pierre Moënne-Loccoz, David J. Schuller, Thomas L. Poulos, Thomas M. Loehr, and Paul R. Ortiz de Montellano
Replacement of the Distal Glycine 139 Transforms Human Heme Oxygenase-1 into a Peroxidase
J. Biol. Chem. 2000 275: 34501-34507. Published as JBC Papers in Press 10.1074/jbc.M004245200 [Abstract] [Full Text] [PDF]  

Yumiko Nagao, Sakae Kitada, Katsuhiko Kojima, Hidehiro Toh, Satoru Kuhara, Tadashi Ogishima, and Akio Ito
Glycine-rich Region of Mitochondrial Processing Peptidase alpha -Subunit Is Essential for Binding and Cleavage of the Precursor Proteins
J. Biol. Chem. 2000 275: 34552-34556. Published as JBC Papers in Press 10.1074/jbc.M003110200 [Abstract] [Full Text] [PDF]  

Nikos G. Oikonomakos, Joachim B. Schnier, Spyros E. Zographos, Vicky T. Skamnaki, Katerina E. Tsitsanou, and Louise N. Johnson
Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site
J. Biol. Chem. 2000 275: 34566-34573. Published as JBC Papers in Press 10.1074/jbc.M004485200 [Abstract] [Full Text] [PDF]  

Lars C. Pedersen, Kazunori Tsuchida, Hiroshi Kitagawa, Kazuyuki Sugahara, Thomas A. Darden, and Masahiko Negishi
Heparan/Chondroitin Sulfate Biosynthesis. STRUCTURE AND MECHANISM OF HUMAN GLUCURONYLTRANSFERASE I
J. Biol. Chem. 2000 275: 34580-34585. Published as JBC Papers in Press 10.1074/jbc.M007399200 [Abstract] [Full Text] [PDF]  

Fardin Hosseinpour and Kjell Wikvall
Porcine Microsomal Vitamin D3 25-Hydroxylase (CYP2D25). CATALYTIC PROPERTIES, TISSUE DISTRIBUTION, AND COMPARISON WITH HUMAN CYP2D6
J. Biol. Chem. 2000 275: 34650-34655. Published as JBC Papers in Press 10.1074/jbc.M004185200 [Abstract] [Full Text] [PDF]  

Alexandre E. Escargueil, Sergei Y. Plisov, Odile Filhol, Claude Cochet, and Annette K. Larsen
Mitotic Phosphorylation of DNA Topoisomerase II alpha by Protein Kinase CK2 Creates the MPM-2 Phosphoepitope on Ser-1469
J. Biol. Chem. 2000 275: 34710-34718. Published as JBC Papers in Press 10.1074/jbc.M005179200 [Abstract] [Full Text] [PDF]  

Kazuaki Homma, Junya Saito, Reiko Ikebe, and Mitsuo Ikebe
Ca2+-dependent Regulation of the Motor Activity of Myosin V
J. Biol. Chem. 2000 275: 34766-34771. Published as JBC Papers in Press 10.1074/jbc.M003132200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Peter J. Eastmond, Mark A. Hooks, Dawn Williams, Peter Lange, Nichole Bechtold, Catherine Sarrobert, Laurent Nussaume, and Ian A. Graham
Promoter Trapping of a Novel Medium-chain Acyl-CoA Oxidase, Which Is Induced Transcriptionally during Arabidopsis Seed Germination
J. Biol. Chem. 2000 275: 34375-34381. Published as JBC Papers in Press 10.1074/jbc.M004945200 [Abstract] [Full Text] [PDF]  

Laurie Baggio, Feisal Adatia, Troels Bock, Patricia L. Brubaker, and Daniel J. Drucker
Sustained Expression of Exendin-4 Does Not Perturb Glucose Homeostasis, beta -Cell Mass, or Food Intake in Metallothionein-Preproexendin Transgenic Mice
J. Biol. Chem. 2000 275: 34471-34477. Published as JBC Papers in Press 10.1074/jbc.M005119200 [Abstract] [Full Text] [PDF]  

Philippe Valet, Danica Grujic, Jennifer Wade, Moriko Ito, M. Cristina Zingaretti, Veronika Soloveva, Susan R. Ross, Reed A. Graves, Saverio Cinti, Max Lafontan, and Bradford B. Lowell
Expression of Human alpha 2-Adrenergic Receptors in Adipose Tissue of beta 3-Adrenergic Receptor-deficient Mice Promotes Diet-induced Obesity
J. Biol. Chem. 2000 275: 34797-34802. Published as JBC Papers in Press 10.1074/jbc.M005210200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Ruixiang Li, Jessica Manela, Yu Kong, and Stephan Ladisch
Cellular Gangliosides Promote Growth Factor-induced Proliferation of Fibroblasts
J. Biol. Chem. 2000 275: 34213-34223. Published as JBC Papers in Press 10.1074/jbc.M906368199 [Abstract] [Full Text] [PDF]  

Kathleen M. Daumer, Ahsan U. Khan, and Marla J. Steinbeck
Chlorination of Pyridinium Compounds. POSSIBLE ROLE OF HYPOCHLORITE, N-CHLORAMINES, AND CHLORINE IN THE OXIDATION OF PYRIDINOLINE CROSS-LINKS OF ARTICULAR CARTILAGE COLLAGEN TYPE II DURING ACUTE INFLAMMATION
J. Biol. Chem. 2000 275: 34681-34692. Published as JBC Papers in Press 10.1074/jbc.M002003200 [Abstract] [Full Text] [PDF]  

Kohji Kasahara, Kazutada Watanabe, Kosei Takeuchi, Harumi Kaneko, Atsuhiko Oohira, Tadashi Yamamoto, and Yutaka Sanai
Involvement of Gangliosides in Glycosylphosphatidylinositol-anchored Neuronal Cell Adhesion Molecule TAG-1 Signaling in Lipid Rafts
J. Biol. Chem. 2000 275: 34701-34709. Published as JBC Papers in Press 10.1074/jbc.M003163200 [Abstract] [Full Text] [PDF]  

Yuki Ito and Osami Habuchi
Purification and Characterization of N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase from the Squid Cartilage
J. Biol. Chem. 2000 275: 34728-34736. Published as JBC Papers in Press 10.1074/jbc.M909633199 [Abstract] [Full Text] [PDF]  

Xun Xie, Anne-Sophie Rivier, Andreas Zakrzewicz, Michael Bernimoulin, Xian-Lu Zeng, Hans Peter Wessel, Marc Schapira, and Olivier Spertini
Inhibition of Selectin-mediated Cell Adhesion and Prevention of Acute Inflammation by Nonanticoagulant Sulfated Saccharides. STUDIES WITH CARBOXYL-REDUCED AND SULFATED HEPARIN AND WITH TRESTATIN A SULFATE
J. Biol. Chem. 2000 275: 34818-34825. Published as JBC Papers in Press 10.1074/jbc.M001257200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Sissel Lund-Katz, Mohamed Zaiou, Suzanne Wehrli, Padmaja Dhanasekaran, Faye Baldwin, Karl H. Weisgraber, and Michael C. Phillips
Effects of Lipid Interaction on the Lysine Microenvironments in Apolipoprotein E
J. Biol. Chem. 2000 275: 34459-34464. Published as JBC Papers in Press 10.1074/jbc.M005265200 [Abstract] [Full Text] [PDF]  

John F. Oram, Richard M. Lawn, Michael R. Garvin, and David P. Wade
ABCA1 Is the cAMP-inducible Apolipoprotein Receptor That Mediates Cholesterol Secretion from Macrophages
J. Biol. Chem. 2000 275: 34508-34511. Published as JBC Papers in Press 10.1074/jbc.M006738200 [Abstract] [Full Text] [PDF]  

Scot J. Stone and Jean E. Vance
Phosphatidylserine Synthase-1 and -2 Are Localized to Mitochondria-associated Membranes
J. Biol. Chem. 2000 275: 34534-34540. Published as JBC Papers in Press 10.1074/jbc.M002865200 [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Masayoshi Fukasawa, Masahiro Nishijima, Hiroyuki Itabe, Tatsuya Takano, and Kentaro Hanada
Reduction of Sphingomyelin Level without Accumulation of Ceramide in Chinese Hamster Ovary Cells Affects Detergent-resistant Membrane Domains and Enhances Cellular Cholesterol Efflux to Methyl-beta -cyclodextrin
J. Biol. Chem. 2000 275: 34028-34034. Published as JBC Papers in Press 10.1074/jbc.M005151200 [Abstract] [Full Text] [PDF]  

Wolfram Antonin, Hellmuth-Alexander Meyer, and Enno Hartmann
Interactions between Spc2p and Other Components of the Endoplasmic Reticulum Translocation Sites of the Yeast Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 34068-34072. Published as JBC Papers in Press 10.1074/jbc.M006126200 [Abstract] [Full Text] [PDF]  

Marga G. W. Gunnewijk and Bert Poolman
Phosphorylation State of HPr Determines the Level of Expression and the Extent of Phosphorylation of the Lactose Transport Protein of Streptococcus thermophilus
J. Biol. Chem. 2000 275: 34073-34079. Published as JBC Papers in Press 10.1074/jbc.M003512200 [Abstract] [Full Text] [PDF]  

Marga G. W. Gunnewijk and Bert Poolman
HPr(His~P)-mediated Phosphorylation Differently Affects Counterflow and Proton Motive Force-driven Uptake via the Lactose Transport Protein of Streptococcus thermophilus
J. Biol. Chem. 2000 275: 34080-34085. Published as JBC Papers in Press 10.1074/jbc.M003513200 [Abstract] [Full Text] [PDF]  

Estelle R. Bennett, Hailing Su, and Baruch I. Kanner
Mutation of Arginine 44 of GAT-1, a (Na+ + Cl-)-coupled gamma -Aminobutyric Acid Transporter from Rat Brain, Impairs Net Flux but Not Exchange
J. Biol. Chem. 2000 275: 34106-34113. Published as JBC Papers in Press 10.1074/jbc.M004229200 [Abstract] [Full Text] [PDF]  

Fernando Doñate, Alejandro J. Yañez, Ana Iriarte, and Marino Martinez-Carrion
Interaction of the Precursor to Mitochondrial Aspartate Aminotransferase and Its Presequence Peptide with Model Membranes
J. Biol. Chem. 2000 275: 34147-34156. Published as JBC Papers in Press 10.1074/jbc.M004494200 [Abstract] [Full Text] [PDF]  

William Foster, Andrew Helm, Isaiah Turnbull, Harnik Gulati, Baoxue Yang, Alan S. Verkman, and William R. Skach
Identification of Sequence Determinants That Direct Different Intracellular Folding Pathways for Aquaporin-1 and Aquaporin-4
J. Biol. Chem. 2000 275: 34157-34165. Published as JBC Papers in Press 10.1074/jbc.M000165200 [Abstract] [Full Text] [PDF]  

Qingcheng Mao, Roger G. Deeley, and Susan P. C. Cole
Functional Reconstitution of Substrate Transport by Purified Multidrug Resistance Protein MRP1 (ABCC1) in Phospholipid Vesicles
J. Biol. Chem. 2000 275: 34166-34172. Published as JBC Papers in Press 10.1074/jbc.M004584200 [Abstract] [Full Text] [PDF]  

Lin-Hua Jiang, François Rassendren, Annmarie Surprenant, and R. Alan North
Identification of Amino Acid Residues Contributing to the ATP-binding Site of a Purinergic P2X Receptor
J. Biol. Chem. 2000 275: 34190-34196. Published as JBC Papers in Press 10.1074/jbc.M005481200 [Abstract] [Full Text] [PDF]  

Li-Yuan Chen, Baochuan Lin, Chi-Jiunn Pan, Hisayuki Hiraiwa, and Janice Yang Chou
Structural Requirements for the Stability and Microsomal Transport Activity of the Human Glucose 6-Phosphate Transporter
J. Biol. Chem. 2000 275: 34280-34286. Published as JBC Papers in Press 10.1074/jbc.M006439200 [Abstract] [Full Text] [PDF]  

Sophie Cornillon, Emmanuel Pech, Mohammed Benghezal, Kissia Ravanel, Erin Gaynor, François Letourneur, Franz Brückert, and Pierre Cosson
Phg1p Is a Nine-transmembrane Protein Superfamily Member Involved in Dictyostelium Adhesion and Phagocytosis
J. Biol. Chem. 2000 275: 34287-34292. Published as JBC Papers in Press 10.1074/jbc.M006725200 [Abstract] [Full Text] [PDF]  

Mitsuko Hayashi, Hiroshi Yamada, Toshihide Mitamura, Toshihiro Horii, Akitsugu Yamamoto, and Yoshinori Moriyama
Vacuolar H+-ATPase Localized in Plasma Membranes of Malaria Parasite Cells, Plasmodium falciparum, Is Involved in Regional Acidification of Parasitized Erythrocytes
J. Biol. Chem. 2000 275: 34353-34358. Published as JBC Papers in Press 10.1074/jbc.M003323200 [Abstract] [Full Text] [PDF]  

Ettickan Boopathi, Hindupur K. Anandatheerthavarada, Shripad V. Bhagwat, Gopa Biswas, Ji-Kang Fang, and Narayan G. Avadhani
Accumulation of Mitochondrial P450MT2, NH2-terminal Truncated Cytochrome P4501A1 in Rat Brain during Chronic Treatment with beta -Naphthoflavone. A ROLE IN THE METABOLISM OF NEUROACTIVE DRUGS
J. Biol. Chem. 2000 275: 34415-34423. Published as JBC Papers in Press 10.1074/jbc.M004431200 [Abstract] [Full Text] [PDF]  

Sheryl E. Koch, Ilona Bodi, Arnold Schwartz, and Gyula Varadi
Architecture of Ca2+ Channel Pore-lining Segments Revealed by Covalent Modification of Substituted Cysteines
J. Biol. Chem. 2000 275: 34493-34500. Published as JBC Papers in Press 10.1074/jbc.M005569200 [Abstract] [Full Text] [PDF]  

Marina S. Feschenko, Elizabeth Stevenson, and Kathleen J. Sweadner
Interaction of Protein Kinase C and cAMP-dependent Pathways in the Phosphorylation of the Na,K-ATPase
J. Biol. Chem. 2000 275: 34693-34700. Published as JBC Papers in Press 10.1074/jbc.M005869200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Sang H. Rhee and Daniel Hwang
Murine TOLL-like Receptor 4 Confers Lipopolysaccharide Responsiveness as Determined by Activation of NFkappa B and Expression of the Inducible Cyclooxygenase
J. Biol. Chem. 2000 275: 34035-34040. Published as JBC Papers in Press 10.1074/jbc.M007386200 [Abstract] [Full Text] [PDF]  

Gutian Xiao, Edward W. Harhaj, and Shao-Cong Sun
Domain-specific Interaction with the Ikappa B Kinase (IKK) Regulatory Subunit IKKgamma Is an Essential Step in Tax-mediated Activation of IKK
J. Biol. Chem. 2000 275: 34060-34067. Published as JBC Papers in Press 10.1074/jbc.M002970200 [Abstract] [Full Text] [PDF]  

Motoyuki Otsuka, Naoya Kato, Keng-Hsin Lan, Hideo Yoshida, Jun Kato, Tadashi Goto, Yasushi Shiratori, and Masao Omata
Hepatitis C Virus Core Protein Enhances p53 Function through Augmentation of DNA Binding Affinity and Transcriptional Ability
J. Biol. Chem. 2000 275: 34122-34130. Published as JBC Papers in Press 10.1074/jbc.M000578200 [Abstract] [Full Text] [PDF]  

Christopher A. Haskell, Michael D. Cleary, and Israel F. Charo
Unique Role of the Chemokine Domain of Fractalkine in Cell Capture. KINETICS OF RECEPTOR DISSOCIATION CORRELATE WITH CELL ADHESION
J. Biol. Chem. 2000 275: 34183-34189. Published as JBC Papers in Press 10.1074/jbc.M005731200 [Abstract] [Full Text] [PDF]  

Yan-Ling Zhang, Zhu-Jun Yao, Mauro Sarmiento, Li Wu, Terrence R. Burke, Jr., and Zhong-Yin Zhang
Thermodynamic Study of Ligand Binding to Protein-tyrosine Phosphatase 1B and Its Substrate-trapping Mutants
J. Biol. Chem. 2000 275: 34205-34212. Published as JBC Papers in Press 10.1074/jbc.M004490200 [Abstract] [Full Text] [PDF]  

Yuchun Gu and Stephen J. Publicover
Expression of Functional Metabotropic Glutamate Receptors in Primary Cultured Rat Osteoblasts. CROSS-TALK WITH N-METHYL-D-ASPARTATE RECEPTORS
J. Biol. Chem. 2000 275: 34252-34259. Published as JBC Papers in Press 10.1074/jbc.M004520200 [Abstract] [Full Text] [PDF]  

Robert J. Crowder and Robert S. Freeman
Glycogen Synthase Kinase-3beta Activity Is Critical for Neuronal Death Caused by Inhibiting Phosphatidylinositol 3-Kinase or Akt but Not for Death Caused by Nerve Growth Factor Withdrawal
J. Biol. Chem. 2000 275: 34266-34271. Published as JBC Papers in Press 10.1074/jbc.M006160200 [Abstract] [Full Text] [PDF]  

Takahiro Yamashita, Akihisa Terakita, and Yoshinori Shichida
Distinct Roles of the Second and Third Cytoplasmic Loops of Bovine Rhodopsin in G Protein Activation
J. Biol. Chem. 2000 275: 34272-34279. Published as JBC Papers in Press 10.1074/jbc.M002954200 [Abstract] [Full Text] [PDF]  

Yasuo Nemoto, Brian G. Kearns, Markus R. Wenk, Hong Chen, Kensaku Mori, James G. Alb, Jr., Pietro De Camilli, and Vytas A. Bankaitis
Functional Characterization of a Mammalian Sac1 and Mutants Exhibiting Substrate-specific Defects in Phosphoinositide Phosphatase Activity
J. Biol. Chem. 2000 275: 34293-34305. Published as JBC Papers in Press 10.1074/jbc.M003923200 [Abstract] [Full Text] [PDF]  

Rongtuan Lin, Yael Mamane, and John Hiscott
Multiple Regulatory Domains Control IRF-7 Activity in Response to Virus Infection
J. Biol. Chem. 2000 275: 34320-34327. Published as JBC Papers in Press 10.1074/jbc.M002814200 [Abstract] [Full Text] [PDF]  

Shenghao Jin, Bo Zhai, Zilong Qiu, Jiarui Wu, M. Daniel Lane, and Kan Liao
c-Crk, a Substrate of the Insulin-like Growth Factor-1 Receptor Tyrosine Kinase, Functions as an Early Signal Mediator in the Adipocyte Differentiation Process
J. Biol. Chem. 2000 275: 34344-34352. Published as JBC Papers in Press 10.1074/jbc.M004927200 [Abstract] [Full Text] [PDF]  

Toshihide Hinoi, Hideki Yamamoto, Michiko Kishida, Shinji Takada, Shosei Kishida, and Akira Kikuchi
Complex Formation of Adenomatous Polyposis Coli Gene Product and Axin Facilitates Glycogen Synthase Kinase-3beta -dependent Phosphorylation of beta -Catenin and Down-regulates beta -Catenin
J. Biol. Chem. 2000 275: 34399-34406. Published as JBC Papers in Press 10.1074/jbc.M003997200 [Abstract] [Full Text] [PDF]  

Savraj S. Grewal, Daniel M. Fass, Hong Yao, Cindy L. Ellig, Richard H. Goodman, and Philip J. S. Stork
Calcium and cAMP Signals Differentially Regulate cAMP-responsive Element-binding Protein Function via a Rap1-Extracellular Signal-regulated Kinase Pathway
J. Biol. Chem. 2000 275: 34433-34441. Published as JBC Papers in Press 10.1074/jbc.M004728200 [Abstract] [Full Text] [PDF]  

Hyongjong Koh, Kyoung Hoa Lee, Dohoon Kim, Sunhong Kim, Jung Woo Kim, and Jongkyeong Chung
Inhibition of Akt and Its Anti-apoptotic Activities by Tumor Necrosis Factor-induced Protein Kinase C-related Kinase 2 (PRK2) Cleavage
J. Biol. Chem. 2000 275: 34451-34458. Published as JBC Papers in Press 10.1074/jbc.M001753200 [Abstract] [Full Text] [PDF]  

Yuichi Hashimoto, Takako Niikura, Yuko Ito, and Ikuo Nishimoto
Multiple Mechanisms Underlie Neurotoxicity by Different Types of Alzheimer's Disease Mutations of Amyloid Precursor Protein
J. Biol. Chem. 2000 275: 34541-34551. Published as JBC Papers in Press 10.1074/jbc.M005332200 [Abstract] [Full Text] [PDF]  

Mikiko Takahashi, Hideyuki Mukai, Kumiko Oishi, Takayuki Isagawa, and Yoshitaka Ono
Association of Immature Hypophosphorylated Protein Kinase Cepsilon with an Anchoring Protein CG-NAP
J. Biol. Chem. 2000 275: 34592-34596. Published as JBC Papers in Press 10.1074/jbc.M005285200 [Abstract] [Full Text] [PDF]  

Julien Davaille, Cyrille Gallois, Aïda Habib, Liying Li, Ariane Mallat, Jiangchuan Tao, Thierry Levade, and Sophie Lotersztajn
Antiproliferative Properties of Sphingosine 1-Phosphate in Human Hepatic Myofibroblasts. A CYCLOOXYGENASE-2 MEDIATED PATHWAY
J. Biol. Chem. 2000 275: 34628-34633. Published as JBC Papers in Press 10.1074/jbc.M006393200 [Abstract] [Full Text] [PDF]  

Niina Reunanen, Marco Foschi, Jiahuai Han, and Veli-Matti Kähäri
Activation of Extracellular Signal-regulated Kinase 1/2 Inhibits Type I Collagen Expression by Human Skin Fibroblasts
J. Biol. Chem. 2000 275: 34634-34639. Published as JBC Papers in Press 10.1074/jbc.C000175200 [Abstract] [Full Text] [PDF]  

Stephen W. G. Tait, Elizabeth B. Reid, David R. Greaves, Thomas E. Wileman, and Penelope P. Powell
Mechanism of Inactivation of NF-kappa B by a Viral Homologue of Ikappa Balpha . SIGNAL-INDUCED RELEASE OF Ikappa Balpha RESULTS IN BINDING OF THE VIRAL HOMOLOGUE TO NF-kappa B
J. Biol. Chem. 2000 275: 34656-34664. Published as JBC Papers in Press 10.1074/jbc.M000320200 [Abstract] [Full Text] [PDF]  

Akira Nakai and Terumi Ishikawa
A Nuclear Localization Signal Is Essential for Stress-induced Dimer-to-Trimer Transition of Heat Shock Transcription Factor 3
J. Biol. Chem. 2000 275: 34665-34671. Published as JBC Papers in Press 10.1074/jbc.M005302200 [Abstract] [Full Text] [PDF]  

Marieke von Lindern, Martine Parren-van Amelsvoort, Thamar van Dijk, Evi Deiner, Emile van den Akker, Sjenet van Emst-de Vries, Peter Willems, Hartmut Beug, and Bob Löwenberg
Protein Kinase C alpha Controls Erythropoietin Receptor Signaling
J. Biol. Chem. 2000 275: 34719-34727. Published as JBC Papers in Press 10.1074/jbc.M007042200 [Abstract] [Full Text] [PDF]  

Wenli Zhou and Graham Carpenter
Heregulin-dependent Trafficking and Cleavage of ErbB-4
J. Biol. Chem. 2000 275: 34737-34743. Published as JBC Papers in Press 10.1074/jbc.M003756200 [Abstract] [Full Text] [PDF]  

Aiyang Cheng, Philipp Kaldis, and Mark J. Solomon
Dephosphorylation of Human Cyclin-dependent Kinases by Protein Phosphatase Type 2Calpha and beta 2 Isoforms
J. Biol. Chem. 2000 275: 34744-34749. Published as JBC Papers in Press 10.1074/jbc.M006210200 [Abstract] [Full Text] [PDF]  

Denis B. Buxton and Robert S. Adelstein
Calcium-dependent Threonine Phosphorylation of Nonmuscle Myosin in Stimulated RBL-2H3 Mast Cells
J. Biol. Chem. 2000 275: 34772-34779. Published as JBC Papers in Press 10.1074/jbc.M004996200 [Abstract] [Full Text] [PDF]  

Annemiek D. Tepper, Sander H. Diks, Wim J. van Blitterswijk, and Jannie Borst
Glucosylceramide Synthase Does Not Attenuate the Ceramide Pool Accumulating during Apoptosis Induced by CD95 or Anti-cancer Regimens
J. Biol. Chem. 2000 275: 34810-34817. Published as JBC Papers in Press 10.1074/jbc.M005142200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Peter Gaines, Justin N. Geiger, Geoff Knudsen, Dhaya Seshasayee, and Don M. Wojchowski
GATA-1- and FOG-dependent Activation of Megakaryocytic alpha IIB Gene Expression
J. Biol. Chem. 2000 275: 34114-34121. Published as JBC Papers in Press 10.1074/jbc.M006017200 [Abstract] [Full Text] [PDF]  

Donna L. Morrison, Arthur Yee, Harry B. Paddon, Dino Vilimek, Ruedi Aebersold, and Steven L. Pelech
Regulation of the Meiosis-inhibited Protein Kinase, a p38MAPK Isoform, During Meiosis and Following Fertilization of Seastar Oocytes
J. Biol. Chem. 2000 275: 34236-34244. Published as JBC Papers in Press 10.1074/jbc.M004656200 [Abstract] [Full Text] [PDF]  

Annette Schuler-Metz, Sigrun Knöchel, Eckhard Kaufmann, and Walter Knöchel
The Homeodomain Transcription Factor Xvent-2 Mediates Autocatalytic Regulation of BMP-4 Expression in Xenopus Embryos
J. Biol. Chem. 2000 275: 34365-34374. Published as JBC Papers in Press 10.1074/jbc.M003915200 [Abstract] [Full Text] [PDF]  

Yann D. Dean, Eamon P. McGreal, Hiroyasu Akatsu, and Philippe Gasque
Molecular and Cellular Properties of the Rat AA4 Antigen, a C-type Lectin-like Receptor with Structural Homology to Thrombomodulin
J. Biol. Chem. 2000 275: 34382-34392. Published as JBC Papers in Press 10.1074/jbc.M006229200 [Abstract] [Full Text] [PDF]  

Alexander Jian Mao, John Bechberger, Darcy Lidington, Jacques Galipeau, Dale W. Laird, and Christian C. G. Naus
Neuronal Differentiation and Growth Control of Neuro-2a Cells After Retroviral Gene Delivery of Connexin43
J. Biol. Chem. 2000 275: 34407-34414. Published as JBC Papers in Press 10.1074/jbc.M003917200 [Abstract] [Full Text] [PDF]  

Yael Tamir and Eyal Bengal
Phosphoinositide 3-Kinase Induces the Transcriptional Activity of MEF2 Proteins during Muscle Differentiation
J. Biol. Chem. 2000 275: 34424-34432. Published as JBC Papers in Press 10.1074/jbc.M005815200 [Abstract] [Full Text] [PDF]  

Kristen R. Taylor, Alison K. Holzer, J. Fernando Bazan, Christopher A. Walsh, and Joseph G. Gleeson
Patient Mutations in Doublecortin Define a Repeated Tubulin-binding Domain
J. Biol. Chem. 2000 275: 34442-34450. Published as JBC Papers in Press 10.1074/jbc.M007078200 [Abstract] [Full Text] [PDF]  

Koichi Ayukawa, Shun'ichiro Taniguchi, Junya Masumoto, Shigenari Hashimoto, Haritha Sarvotham, Astushi Hara, Toshifumi Aoyama, and Junji Sagara
La Autoantigen Is Cleaved in the COOH Terminus and Loses the Nuclear Localization Signal during Apoptosis
J. Biol. Chem. 2000 275: 34465-34470. Published as JBC Papers in Press 10.1074/jbc.M003673200 [Abstract] [Full Text] [PDF]  

Satoshi Komatsu, Takeo Yano, Masao Shibata, Richard A. Tuft, and Mitsuo Ikebe
Effects of the Regulatory Light Chain Phosphorylation of Myosin II on Mitosis and Cytokinesis of Mammalian Cells
J. Biol. Chem. 2000 275: 34512-34520. Published as JBC Papers in Press 10.1074/jbc.M003019200 [Abstract] [Full Text] [PDF]  

Ichiro Izawa, Miwako Nishizawa, Kazuhiro Ohtakara, Kenzo Ohtsuka, Hiroyasu Inada, and Masaki Inagaki
Identification of Mrj, a DnaJ/Hsp40 Family Protein, as a Keratin 8/18 Filament Regulatory Protein
J. Biol. Chem. 2000 275: 34521-34527. Published as JBC Papers in Press 10.1074/jbc.M003492200 [Abstract] [Full Text] [PDF]  

Shuichi Saito, Yukio Hiroi, Yunzeng Zou, Ryuichi Aikawa, Haruhiro Toko, Futoshi Shibasaki, Yoshio Yazaki, Ryozo Nagai, and Issei Komuro
beta -Adrenergic Pathway Induces Apoptosis through Calcineurin Activation in Cardiac Myocytes
J. Biol. Chem. 2000 275: 34528-34533. Published as JBC Papers in Press 10.1074/jbc.M002844200 [Abstract] [Full Text] [PDF]  

Sonia A. Cunningham, M. Pia Arrate, Jose M. Rodriguez, Robert J. Bjercke, Peter Vanderslice, Andrew P. Morris, and Tommy A. Brock
A Novel Protein with Homology to the Junctional Adhesion Molecule. CHARACTERIZATION OF LEUKOCYTE INTERACTIONS
J. Biol. Chem. 2000 275: 34750-34756. Published as JBC Papers in Press 10.1074/jbc.M002718200 [Abstract] [Full Text] [PDF]  


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