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Table of Contents: Feb 18 2000; 275 (7)   [Index by Author]       Other Issues:  
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Genomics Proteomics and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Accelerated Publications:

Diane L. Sherman and Peter J. Brophy
A Tripartite Nuclear Localization Signal in the PDZ-domain Protein L-periaxin
J. Biol. Chem. 2000 275: 4537-4540. [Abstract] [Full Text] [PDF]  

Xiao Yi Yang, Li Hua Wang, Taosheng Chen, David R. Hodge, James H. Resau, Luis DaSilva, and William L. Farrar
Activation of Human T Lymphocytes Is Inhibited by Peroxisome Proliferator-activated Receptor gamma  (PPARgamma ) Agonists. PPARgamma CO-ASSOCIATION WITH TRANSCRIPTION FACTOR NFAT
J. Biol. Chem. 2000 275: 4541-4544. [Abstract] [Full Text] [PDF]  

Francisco J. Naya, Brian Mercer, John Shelton, James A. Richardson, R. Sanders Williams, and Eric N. Olson
Stimulation of Slow Skeletal Muscle Fiber Gene Expression by Calcineurin in Vivo
J. Biol. Chem. 2000 275: 4545-4548. [Abstract] [Full Text] [PDF]  


DNA: Replication Repair and Recombination:

Kenjiro Asagoshi, Takao Yamada, Hiroaki Terato, Yoshihiko Ohyama, Yoshiaki Monden, Tsuyoshi Arai, Susumu Nishimura, Hiroyuki Aburatani, Tomas Lindahl, and Hiroshi Ide
Distinct Repair Activities of Human 7,8-Dihydro-8-oxoguanine DNA Glycosylase and Formamidopyrimidine DNA Glycosylase for Formamidopyrimidine and 7,8-Dihydro-8-oxoguanine
J. Biol. Chem. 2000 275: 4956-4964. [Abstract] [Full Text] [PDF]  

Esther E. A. Verhoeven, Marian van Kesteren, Geri F. Moolenaar, Rob Visse, and Nora Goosen
Catalytic Sites for 3' and 5' Incision of Escherichia coli Nucleotide Excision Repair Are Both Located in UvrC
J. Biol. Chem. 2000 275: 5120-5123. [Abstract] [Full Text] [PDF]  

Shaojun Zuo, Vladimir Bermudez, Gang Zhang, Zvi Kelman, and Jerard Hurwitz
Structure and Activity Associated with Multiple Forms of Schizosaccharomyces pombe DNA Polymerase delta
J. Biol. Chem. 2000 275: 5153-5162. [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Ik-Jae Moon, Kyusam Choi, Young-Kook Choi, Ji-Eyon Kim, Youngik Lee, Alan D. Schreiber, and Jong-Gu Park
Potent Growth Inhibition of Leukemic Cells by Novel Ribbon-type Antisense Oligonucleotides to c-myb1
J. Biol. Chem. 2000 275: 4647-4653. [Abstract] [Full Text] [PDF]  

Guanghui Wu, Hugo Cruz-Ramos, Susan Hill, Jeff Green, Gary Sawers, and Robert K. Poole
Regulation of Cytochrome bd Expression in the Obligate Aerobe Azotobacter vinelandii by CydR (Fnr). SENSITIVITY TO OXYGEN, REACTIVE OXYGEN SPECIES, AND NITRIC OXIDE
J. Biol. Chem. 2000 275: 4679-4686. [Abstract] [Full Text] [PDF]  

Neil R. Chapman and Neil D. Perkins
Inhibition of the RelA(p65) NF-kappa B Subunit by Egr-1
J. Biol. Chem. 2000 275: 4719-4725. [Abstract] [Full Text] [PDF]  

Andrea Cabibbo, Massimiliano Pagani, Marco Fabbri, Mariano Rocchi, Mark R. Farmery, Neil J. Bulleid, and Roberto Sitia
ERO1-L, a Human Protein That Favors Disulfide Bond Formation in the Endoplasmic Reticulum
J. Biol. Chem. 2000 275: 4827-4833. [Abstract] [Full Text] [PDF]  

Sabine Thébault, Frédéric Gachon, Isabelle Lemasson, Christian Devaux, and Jean-Michel Mesnard
Molecular Cloning of a Novel Human I-mfa Domain-containing Protein That Differently Regulates Human T-cell Leukemia Virus Type I and HIV-1 Expression
J. Biol. Chem. 2000 275: 4848-4857. [Abstract] [Full Text] [PDF]  

Nagarajan Selvamurugan, Malini R. Pulumati, Darren R. Tyson, and Nicola C. Partridge
Parathyroid Hormone Regulation of the Rat Collagenase-3 Promoter by Protein Kinase A-dependent Transactivation of Core Binding Factor alpha 1
J. Biol. Chem. 2000 275: 5037-5042. [Abstract] [Full Text] [PDF]  

Steven D. Chessler and Åke Lernmark
Alternative Splicing of GAD67 Results in the Synthesis of a Third Form of Glutamic-acid Decarboxylase in Human Islets and Other Non-neural Tissues
J. Biol. Chem. 2000 275: 5188-5192. [Abstract] [Full Text] [PDF]  

Seung-Hoi Koo and Howard C. Towle
Glucose Regulation of Mouse S14 Gene Expression in Hepatocytes. INVOLVEMENT OF A NOVEL TRANSCRIPTION FACTOR COMPLEX
J. Biol. Chem. 2000 275: 5200-5207. [Abstract] [Full Text] [PDF]  

Jingwen Liu, Thomas E. Ahlborn, Michael R. Briggs, and Fredric B. Kraemer
Identification of a Novel Sterol-independent Regulatory Element in the Human Low Density Lipoprotein Receptor Promoter
J. Biol. Chem. 2000 275: 5214-5221. [Abstract] [Full Text] [PDF]  


RNA: Structure Metabolism and Catalysis:

Jay R. Hesselberth, Darcie Miller, Jon Robertus, and Andrew D. Ellington
In Vitro Selection of RNA Molecules That Inhibit the Activity of Ricin A-chain
J. Biol. Chem. 2000 275: 4937-4942. [Abstract] [Full Text] [PDF]  

Ichiro Hirao, Kairat Madin, Yaeta Endo, Shigeyuki Yokoyama, and Andrew D. Ellington
RNA Aptamers That Bind to and Inhibit the Ribosome-inactivating Protein, Pepocin
J. Biol. Chem. 2000 275: 4943-4948. [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

David Lando, Ingemar Pongratz, Lorenz Poellinger, and Murray L. Whitelaw
A Redox Mechanism Controls Differential DNA Binding Activities of Hypoxia-inducible Factor (HIF) 1alpha and the HIF-like Factor
J. Biol. Chem. 2000 275: 4618-4627. [Abstract] [Full Text] [PDF]  

Yayoi Kimura, Motoko Takaoka, Sono Tanaka, Hidenori Sassa, Keiji Tanaka, Bogdan Polevoda, Fred Sherman, and Hisashi Hirano
Nalpha -Acetylation and Proteolytic Activity of the Yeast 20 S Proteasome
J. Biol. Chem. 2000 275: 4635-4639. [Abstract] [Full Text] [PDF]  

Yuwei Zhao and Theodore Mazzone
Transport and Processing of Endogenously Synthesized ApoE on the Macrophage Cell Surface
J. Biol. Chem. 2000 275: 4759-4765. [Abstract] [Full Text] [PDF]  

Lorraine B. Anderson, Anthony J. A. Ouellette, and Bridgette A. Barry
Probing the Structure of Photosystem II with Amines and Phenylhydrazine
J. Biol. Chem. 2000 275: 4920-4927. [Abstract] [Full Text] [PDF]  

Dong Hui Chung, Kazuteru Ohashi, Makoto Watanabe, Nobuyuki Miyasaka, and Shinsaku Hirosawa
Mannose Trimming Targets Mutant alpha 2-Plasmin Inhibitor for Degradation by the Proteasome
J. Biol. Chem. 2000 275: 4981-4987. [Abstract] [Full Text] [PDF]  

Kevin C. Graham and David W. Litchfield
The Regulatory beta  Subunit of Protein Kinase CK2 Mediates Formation of Tetrameric CK2 Complexes
J. Biol. Chem. 2000 275: 5003-5010. [Abstract] [Full Text] [PDF]  

Michael Kipp, Birgit L. Schwab, Michael Przybylski, Pierluigi Nicotera, and Frank O. Fackelmayer
Apoptotic Cleavage of Scaffold Attachment Factor A (SAF-A) by Caspase-3 Occurs at a Noncanonical Cleavage Site
J. Biol. Chem. 2000 275: 5031-5036. [Abstract] [Full Text] [PDF]  

Maryam Rafie-Kolpin, Peter J. Chefalo, Zareena Hussain, Joyce Hahn, Sheri Uma, Robert L. Matts, and Jane-Jane Chen
Two Heme-binding Domains of Heme-regulated Eukaryotic Initiation Factor-2alpha Kinase. N TERMINUS AND KINASE INSERTION
J. Biol. Chem. 2000 275: 5171-5178. [Abstract] [Full Text] [PDF]  

Takuma Hayashi and Denise Faustman
Essential Role of Human Leukocyte Antigen-encoded Proteasome Subunits in NF-kappa B Activation and Prevention of Tumor Necrosis Factor-alpha -induced Apoptosis
J. Biol. Chem. 2000 275: 5238-5247. [Abstract] [Full Text] [PDF]  


Genomics Proteomics and Bioinformatics:

Sher Karki, Mariko K. Tokito, and Erika L. F. Holzbaur
A Dynactin Subunit with a Highly Conserved Cysteine-rich Motif Interacts Directly with Arp1
J. Biol. Chem. 2000 275: 4834-4839. [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Amanda L. Salmon, Anders H. Johnsen, Michael Bienert, Gordon McMurray, Kiran A. Nandha, Steve R. Bloom, and Chris Shaw
Isolation, Structural Characterization, and Bioactivity of a Novel Neuromedin U Analog from the Defensive Skin Secretion of the Australasian Tree Frog, Litoria caerulea
J. Biol. Chem. 2000 275: 4549-4554. [Abstract] [Full Text] [PDF] Supplemental Data  

G. Bhanuprakash Reddy, Kali P. Das, J. Mark Petrash, and Witold K. Surewicz
Temperature-dependent Chaperone Activity and Structural Properties of Human alpha A- and alpha B-crystallins
J. Biol. Chem. 2000 275: 4565-4570. [Abstract] [Full Text] [PDF]  

Julie Grantham, Oscar Llorca, Jose M. Valpuesta, and Keith R. Willison
Partial Occlusion of Both Cavities of the Eukaryotic Chaperonin with Antibody Has No Effect upon the Rates of beta -Actin or alpha -Tubulin Folding
J. Biol. Chem. 2000 275: 4587-4591. [Abstract] [Full Text] [PDF]  

Yunxia Wang, Edward S. Bjes, and Alfred F. Esser
Molecular Aspects of Complement-mediated Bacterial Killing. PERIPLASMIC CONVERSION OF C9 FROM A PROTOXIN TO A TOXIN
J. Biol. Chem. 2000 275: 4687-4692. [Abstract] [Full Text] [PDF]  

Ronaldo Mohana-Borges, Ana B. F. Pacheco, Francisco J. R. Sousa, Debora Foguel, Darcy F. Almeida, and Jerson L. Silva
LexA Repressor Forms Stable Dimers in Solution. THE ROLE OF SPECIFIC DNA IN TIGHTENING PROTEIN-PROTEIN INTERACTIONS
J. Biol. Chem. 2000 275: 4708-4712. [Abstract] [Full Text] [PDF]  

Elisabeth E. Tuerk, Jörg Schreiber, and Michael Wegner
Protein Stability and Domain Topology Determine the Transcriptional Activity of the Mammalian Glial Cells Missing Homolog, GCMb
J. Biol. Chem. 2000 275: 4774-4782. [Abstract] [Full Text] [PDF]  

A. H. Jay Burr, Peter Hunt, Donna R. Wagar, Sylvia Dewilde, Mark L. Blaxter, Jacques R. Vanfleteren, and Luc Moens
A Hemoglobin with an Optical Function
J. Biol. Chem. 2000 275: 4810-4815. [Abstract] [Full Text] [PDF]  

Hideaki Shimizu, Eiji Obayashi, Yuki Gomi, Hiroshi Arakawa, Sam-Yong Park, Hiro Nakamura, Shin-ichi Adachi, Hirofumi Shoun, and Yoshitsugu Shiro
Proton Delivery in NO Reduction by Fungal Nitric-oxide Reductase. CRYOGENIC CRYSTALLOGRAPHY, SPECTROSCOPY, AND KINETICS OF FERRIC-NO COMPLEXES OF WILD-TYPE AND MUTANT ENZYMES
J. Biol. Chem. 2000 275: 4816-4826. [Abstract] [Full Text] [PDF]  

Ikuo Matsui, Eriko Matsui, Yukihiro Sakai, Hisasi Kikuchi, Yutaka Kawarabayasi, Hideaki Ura, Shin-ichi Kawaguchi, Seiki Kuramitsu, and Kazuaki Harata
The Molecular Structure of Hyperthermostable Aromatic Aminotransferase with Novel Substrate Specificity from Pyrococcus horikoshii
J. Biol. Chem. 2000 275: 4871-4879. [Abstract] [Full Text] [PDF]  

P. A. Quiram, J. M. McIntosh, and S. M. Sine
Pairwise Interactions between Neuronal alpha 7 Acetylcholine Receptors and alpha -Conotoxin PnIB
J. Biol. Chem. 2000 275: 4889-4896. [Abstract] [Full Text] [PDF]  

Masanori Ochiai and Masaaki Ashida
A Pattern-recognition Protein for beta -1,3-Glucan. THE BINDING DOMAIN AND THE cDNA CLONING OF beta -1,3-GLUCAN RECOGNITION PROTEIN FROM THE SILKWORM, BOMBYX MORI
J. Biol. Chem. 2000 275: 4995-5002. [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Richard J. Heath, Jing Li, Gregory E. Roland, and Charles O. Rock
Inhibition of the Staphylococcus aureus NADPH-dependent Enoyl-Acyl Carrier Protein Reductase by Triclosan and Hexachlorophene
J. Biol. Chem. 2000 275: 4654-4659. [Abstract] [Full Text] [PDF]  

Eisuke Murakami and Stephen W. Ragsdale
Evidence for Intersubunit Communication during Acetyl-CoA Cleavage by the Multienzyme CO Dehydrogenase/Acetyl-CoA Synthase Complex from Methanosarcina thermophila. EVIDENCE THAT THE beta  SUBUNIT CATALYZES C-C AND C-S BOND CLEAVAGE
J. Biol. Chem. 2000 275: 4699-4707. [Abstract] [Full Text] [PDF]  

Claus Schneider and Alan R. Brash
Stereospecificity of Hydrogen Abstraction in the Conversion of Arachidonic Acid to 15R-HETE by Aspirin-treated Cyclooxygenase-2. IMPLICATIONS FOR THE ALIGNMENT OF SUBSTRATE IN THE ACTIVE SITE
J. Biol. Chem. 2000 275: 4743-4746. [Abstract] [Full Text] [PDF]  

Hitesh Patel, Sarkis S. Margossian, and Peter D. Chantler
Locking Regulatory Myosin in the Off-state with Trifluoperazine
J. Biol. Chem. 2000 275: 4880-4888. [Abstract] [Full Text] [PDF]  

William M. Lindstrom, Jr., James Flynn, and Norbert O. Reich
Reconciling Structure and Function in HhaI DNA Cytosine-C-5 Methyltransferase
J. Biol. Chem. 2000 275: 4912-4919. [Abstract] [Full Text] [PDF]  

Yong-Mei Qin, Antti M. Haapalainen, Seppo H. Kilpeläinen, Mari S. Marttila, M. Kristian Koski, Tuomo Glumoff, Dmitry K. Novikov, and J. Kalervo Hiltunen
Human Peroxisomal Multifunctional Enzyme Type 2. SITE-DIRECTED MUTAGENESIS STUDIES SHOW THE IMPORTANCE OF TWO PROTIC RESIDUES FOR 2-ENOYL-CoA HYDRATASE 2 ACTIVITY
J. Biol. Chem. 2000 275: 4965-4972. [Abstract] [Full Text] [PDF]  

Siegel Dan, Ira Marton, Mara Dekel, Ben-Ami Bravdo, Shouming He, Stephen G. Withers, and Oded Shoseyov
Cloning, Expression, Characterization, and Nucleophile Identification of Family 3, Aspergillus niger beta -Glucosidase
J. Biol. Chem. 2000 275: 4973-4980. [Abstract] [Full Text] [PDF]  

Heather J. Montgomery, Vladimir Romanov, and J. Guy Guillemette
Removal of a Putative Inhibitory Element Reduces the Calcium-dependent Calmodulin Activation of Neuronal Nitric-oxide Synthase
J. Biol. Chem. 2000 275: 5052-5058. [Abstract] [Full Text] [PDF]  

Farah Javid-Majd, Leisha S. Mullins, Frank M. Raushel, and Michelle A. Stapleton
The Differentially Conserved Residues of Carbamoyl-Phosphate Synthetase
J. Biol. Chem. 2000 275: 5073-5080. [Abstract] [Full Text] [PDF]  

Henry J. Windle, Áine Fox, Déirdre Ní Eidhin, and Dermot Kelleher
The Thioredoxin System of Helicobacter pylori
J. Biol. Chem. 2000 275: 5081-5089. [Abstract] [Full Text] [PDF]  

Ingar Janzik, Peter Macheroux, Nikolaus Amrhein, and Andreas Schaller
LeSBT1, a Subtilase from Tomato Plants. OVEREXPRESSION IN INSECT CELLS, PURIFICATION, AND CHARACTERIZATION
J. Biol. Chem. 2000 275: 5193-5199. [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Marisa M. Magaña, Seung-Hoi Koo, Howard C. Towle, and Timothy F. Osborne
Different Sterol Regulatory Element-binding Protein-1 Isoforms Utilize Distinct Co-regulatory Factors to Activate the Promoter for Fatty Acid Synthase
J. Biol. Chem. 2000 275: 4726-4733. [Abstract] [Full Text] [PDF]  

Yi-Qiang Cheng and Jonathan D. Walton
A Eukaryotic Alanine Racemase Gene Involved in Cyclic Peptide Biosynthesis
J. Biol. Chem. 2000 275: 4906-4911. [Abstract] [Full Text] [PDF]  

Virginie Gueguen, David Macherel, Michel Jaquinod, Roland Douce, and Jacques Bourguignon
Fatty Acid and Lipoic Acid Biosynthesis in Higher Plant Mitochondria
J. Biol. Chem. 2000 275: 5016-5025. [Abstract] [Full Text] [PDF]  

Maria Rosa Ciriolo, Angelo De Martino, Emanuela Lafavia, Luisa Rossi, Maria Teresa Carrì, and Giuseppe Rotilio
Cu,Zn-Superoxide Dismutase-dependent Apoptosis Induced by Nitric Oxide in Neuronal Cells
J. Biol. Chem. 2000 275: 5065-5072. [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Malcolm Lyon, Graham Rushton, Janet A. Askari, Martin J. Humphries, and John T. Gallagher
Elucidation of the Structural Features of Heparan Sulfate Important for Interaction with the Hep-2 Domain of Fibronectin
J. Biol. Chem. 2000 275: 4599-4606. [Abstract] [Full Text] [PDF]  

Nancy J. Phillips, Theresa J. Miller, Jeffrey J. Engstrom, William Melaugh, Robert McLaughlin, Michael A. Apicella, and Bradford W. Gibson
Characterization of Chimeric Lipopolysaccharides from Escherichia coli Strain JM109 Transformed with Lipooligosaccharide Synthesis Genes (lsg) from Haemophilus influenzae
J. Biol. Chem. 2000 275: 4747-4758. [Abstract] [Full Text] [PDF]  

Elena G. Novikova, Sandra E. Reznik, Oleg Varlamov, and Lloyd D. Fricker
Carboxypeptidase Z Is Present in the Regulated Secretory Pathway and Extracellular Matrix in Cultured Cells and in Human Tissues
J. Biol. Chem. 2000 275: 4865-4870. [Abstract] [Full Text] [PDF]  

David A. Rasko, Ge Wang, Monica M. Palcic, and Diane E. Taylor
Cloning and Characterization of the alpha (1,3/4) Fucosyltransferase of Helicobacter pylori
J. Biol. Chem. 2000 275: 4988-4994. [Abstract] [Full Text] [PDF]  

Xin Lin, Peter Mattjus, Helen M. Pike, Anthony J. Windebank, and Rhoderick E. Brown
Cloning and Expression of Glycolipid Transfer Protein from Bovine and Porcine Brain
J. Biol. Chem. 2000 275: 5104-5110. [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Mary Y. Chang, Susan Potter-Perigo, Christina Tsoi, Alan Chait, and Thomas N. Wight
Oxidized Low Density Lipoproteins Regulate Synthesis of Monkey Aortic Smooth Muscle Cell Proteoglycans That Have Enhanced Native Low Density Lipoprotein Binding Properties
J. Biol. Chem. 2000 275: 4766-4773. [Abstract] [Full Text] [PDF]  

Dan C. McManus, Brian R. Scott, Philippe G. Frank, Vivian Franklin, Joshua R. Schultz, and Yves L. Marcel
Distinct Central Amphipathic alpha -Helices in Apolipoprotein A-I Contribute to the in Vivo Maturation of High Density Lipoprotein by Either Activating Lecithin-Cholesterol Acyltransferase or Binding Lipids
J. Biol. Chem. 2000 275: 5043-5051. [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Kai Hell, Alexander Tzagoloff, Walter Neupert, and Rosemary A. Stuart
Identification of Cox20p, a Novel Protein Involved in the Maturation and Assembly of Cytochrome Oxidase Subunit 2
J. Biol. Chem. 2000 275: 4571-4578. [Abstract] [Full Text] [PDF]  

Mark Ibberson, Marc Uldry, and Bernard Thorens
GLUTX1, a Novel Mammalian Glucose Transporter Expressed in the Central Nervous System and Insulin-sensitive Tissues
J. Biol. Chem. 2000 275: 4607-4612. [Abstract] [Full Text] [PDF]  

Hiroshi Yoneyama, Hideaki Maseda, Hiroshi Kamiguchi, and Taiji Nakae
Function of the Membrane Fusion Protein, MexA, of the MexA, B-OprM Efflux Pump in Pseudomonas aeruginosa without an Anchoring Membrane
J. Biol. Chem. 2000 275: 4628-4634. [Abstract] [Full Text] [PDF]  

Aoife MacManus, Martin Ramsden, Michael Murray, Zaineb Henderson, Hugh A. Pearson, and Veronica A. Campbell
Enhancement of 45Ca2+ Influx and Voltage-dependent Ca2+ Channel Activity by beta -Amyloid-(1-40) in Rat Cortical Synaptosomes and Cultured Cortical Neurons. MODULATION BY THE PROINFLAMMATORY CYTOKINE INTERLEUKIN-1beta
J. Biol. Chem. 2000 275: 4713-4718. [Abstract] [Full Text] [PDF]  

Miro Venturi, Abraham Rimon, Yoram Gerchman, Carola Hunte, Etana Padan, and Harmut Michel
The Monoclonal Antibody 1F6 Identifies a pH-dependent Conformational Change in the Hydrophilic NH2 Terminus of NhaA Na+/H+ Antiporter of Escherichia coli
J. Biol. Chem. 2000 275: 4734-4742. [Abstract] [Full Text] [PDF]  

Agathe Subtil, Michael A Lampson, Susanna R. Keller, and Timothy E. McGraw
Characterization of the Insulin-regulated Endocytic Recycling Mechanism in 3T3-L1 Adipocytes Using a Novel Reporter Molecule
J. Biol. Chem. 2000 275: 4787-4795. [Abstract] [Full Text] [PDF]  

Thanawath Harris, Mohammad Shahidullah, John S. Ellingson, and Manuel Covarrubias
General Anesthetic Action at an Internal Protein Site Involving the S4-S5 Cytoplasmic Loop of a Neuronal K+ Channel
J. Biol. Chem. 2000 275: 4928-4936. [Abstract] [Full Text] [PDF]  

Gary M. Clifford, Constantine Londos, Fredric B. Kraemer, Richard G. Vernon, and Stephen J. Yeaman
Translocation of Hormone-sensitive Lipase and Perilipin upon Lipolytic Stimulation of Rat Adipocytes
J. Biol. Chem. 2000 275: 5011-5015. [Abstract] [Full Text] [PDF]  

Gert H. Hansen, Lise-Lotte Niels-Christiansen, Evy Thorsen, Lissi Immerdal, and E. Michael Danielsen
Cholesterol Depletion of Enterocytes. EFFECT ON THE GOLGI COMPLEX AND APICAL MEMBRANE TRAFFICKING
J. Biol. Chem. 2000 275: 5136-5142. [Abstract] [Full Text] [PDF]  

Karen D. Sims, Dean J. Straff, and Michael B. Robinson
Platelet-derived Growth Factor Rapidly Increases Activity and Cell Surface Expression of the EAAC1 Subtype of Glutamate Transporter through Activation of Phosphatidylinositol 3-Kinase
J. Biol. Chem. 2000 275: 5228-5237. [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Alexandra Draganescu, Santosh C. Hodawadekar, Kyle R. Gee, and Charles Brenner
Fhit-nucleotide Specificity Probed with Novel Fluorescent and Fluorogenic Substrates
J. Biol. Chem. 2000 275: 4555-4560. [Abstract] [Full Text] [PDF]  

Elena Kaznacheyeva, Alexander Zubov, Anton Nikolaev, Vadim Alexeenko, Ilya Bezprozvanny, and Galina N. Mozhayeva
Plasma Membrane Calcium Channels in Human Carcinoma A431 Cells Are Functionally Coupled to Inositol 1,4,5-Trisphosphate Receptor-Phosphatidylinositol 4,5-Bisphosphate Complexes
J. Biol. Chem. 2000 275: 4561-4564. [Abstract] [Full Text] [PDF]  

Gerhard Müller-Newen, Andrea Küster, John Wijdenes, Fred Schaper, and Peter C. Heinrich
Studies on the Interleukin-6-type Cytokine Signal Transducer gp130 Reveal a Novel Mechanism of Receptor Activation by Monoclonal Antibodies
J. Biol. Chem. 2000 275: 4579-4586. [Abstract] [Full Text] [PDF]  

Paola Chiarugi, Paolo Cirri, Letizia Taddei, Elisa Giannoni, Guido Camici, Giampaolo Manao, Giovanni Raugei, and Giampietro Ramponi
The Low Mr Protein-tyrosine Phosphatase Is Involved in Rho-mediated Cytoskeleton Rearrangement after Integrin and Platelet-derived Growth Factor Stimulation
J. Biol. Chem. 2000 275: 4640-4646. [Abstract] [Full Text] [PDF]  

Jennie Harvey, Neil G. McKay, Kay S. Walker, Jeroen Van der Kaay, C. Peter Downes, and Michael L. J. Ashford
Essential Role of Phosphoinositide 3-Kinase in Leptin-induced KATP Channel Activation in the Rat CRI-G1 Insulinoma Cell Line
J. Biol. Chem. 2000 275: 4660-4669. [Abstract] [Full Text] [PDF]  

Jennifer L. Slack, K. Schooley, Timothy P. Bonnert, Jennifer L. Mitcham, Eva E. Qwarnstrom, John E. Sims, and Steven K. Dower
Identification of Two Major Sites in the Type I Interleukin-1 Receptor Cytoplasmic Region Responsible for Coupling to Pro-inflammatory Signaling Pathways
J. Biol. Chem. 2000 275: 4670-4678. [Abstract] [Full Text] [PDF]  

Sathyamangla V. Naga Prasad, Giovanni Esposito, Lan Mao, Walter J. Koch, and Howard A. Rockman
Gbeta gamma -dependent Phosphoinositide 3-Kinase Activation in Hearts with in Vivo Pressure Overload Hypertrophy
J. Biol. Chem. 2000 275: 4693-4698. [Abstract] [Full Text] [PDF]  

Jesús Balsinde, María A. Balboa, Saul Yedgar, and Edward A. Dennis
Group V Phospholipase A2-mediated Oleic Acid Mobilization in Lipopolysaccharide-stimulated P388D1 Macrophages
J. Biol. Chem. 2000 275: 4783-4786. [Abstract] [Full Text] [PDF]  

Lisa M. Ballou, Michael E. Cross, Siqi Huang, E. Michael McReynolds, Bin-Xian Zhang, and Richard Z. Lin
Differential Regulation of the Phosphatidylinositol 3-Kinase/Akt and p70 S6 Kinase Pathways by the alpha 1A-Adrenergic Receptor in Rat-1 Fibroblasts
J. Biol. Chem. 2000 275: 4803-4809. [Abstract] [Full Text] [PDF]  

Keizo Yuasa, Kenji Omori, and Noriyuki Yanaka
Binding and Phosphorylation of a Novel Male Germ Cell-specific cGMP-dependent Protein Kinase-anchoring Protein by cGMP-dependent Protein Kinase Ialpha
J. Biol. Chem. 2000 275: 4897-4905. [Abstract] [Full Text] [PDF]  

Kerry Strong Russell, M. Page Haynes, Teresa Caulin-Glaser, James Rosneck, William C. Sessa, and Jeffrey R. Bender
Estrogen Stimulates Heat Shock Protein 90 Binding to Endothelial Nitric Oxide Synthase in Human Vascular Endothelial Cells. EFFECTS ON CALCIUM SENSITIVITY AND NO RELEASE
J. Biol. Chem. 2000 275: 5026-5030. [Abstract] [Full Text] [PDF]  

Li-Wha Wu, Lindsey D. Mayo, James D. Dunbar, Kelly M. Kessler, Melinda R. Baerwald, Eric A. Jaffe, Dongfang Wang, Robert S. Warren, and David B. Donner
Utilization of Distinct Signaling Pathways by Receptors for Vascular Endothelial Cell Growth Factor and Other Mitogens in the Induction of Endothelial Cell Proliferation
J. Biol. Chem. 2000 275: 5096-5103. [Abstract] [Full Text] [PDF]  

Frank A. Suprynowicz, Jason Sparkowski, Astrid Baege, and Richard Schlegel
E5 Oncoprotein Mutants Activate Phosphoinositide 3-Kinase Independently of Platelet-derived Growth Factor Receptor Activation
J. Biol. Chem. 2000 275: 5111-5119. [Abstract] [Full Text] [PDF]  

Fei Le, Frank Stomski, Joanna M. Woodcock, Angel F. Lopez, and Thomas J. Gonda
The Role of Disulfide-linked Dimerization in Interleukin-3 Receptor Signaling and Biological Activity
J. Biol. Chem. 2000 275: 5124-5130. [Abstract] [Full Text] [PDF]  

Nancy J. Boerth, Barbi A. Judd, and Gary A. Koretzky
Functional Association between SLAP-130 and SLP-76 in Jurkat T Cells
J. Biol. Chem. 2000 275: 5143-5152. [Abstract] [Full Text] [PDF]  

Elke Butt, Manfred Bernhardt, Albert Smolenski, Peter Kotsonis, Lothar G. Fröhlich, Albert Sickmann, Helmut E. Meyer, Suzanne M. Lohmann, and Harald H. H. W. Schmidt
Endothelial Nitric-oxide Synthase (Type III) Is Activated and Becomes Calcium Independent upon Phosphorylation by Cyclic Nucleotide-dependent Protein Kinases
J. Biol. Chem. 2000 275: 5179-5187. [Abstract] [Full Text] [PDF]  

Kaoru Fukunaga, Tetsuya Noguchi, Hitoshi Takeda, Takashi Matozaki, Yoshitake Hayashi, Hiroshi Itoh, and Masato Kasuga
Requirement for Protein-tyrosine Phosphatase SHP-2 in Insulin-induced Activation of c-Jun NH2-terminal Kinase
J. Biol. Chem. 2000 275: 5208-5213. [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Satoshi Miyata, Naohiko Koshikawa, Hidetaro Yasumitsu, and Kaoru Miyazaki
Trypsin Stimulates Integrin alpha 5beta 1-dependent Adhesion to Fibronectin and Proliferation of Human Gastric Carcinoma Cells through Activation of Proteinase-activated Receptor-2
J. Biol. Chem. 2000 275: 4592-4598. [Abstract] [Full Text] [PDF]  

Jens Lüders, Jens Demand, and Jörg Höhfeld
The Ubiquitin-related BAG-1 Provides a Link between the Molecular Chaperones Hsc70/Hsp70 and the Proteasome
J. Biol. Chem. 2000 275: 4613-4617. [Abstract] [Full Text] [PDF]  

Tracy A. Shahan, Abdelilah Fawzi, Georges Bellon, Jean-Claude Monboisse, and Nicholas A. Kefalides
Regulation of Tumor Cell Chemotaxis by Type IV Collagen Is Mediated by a Ca2+-dependent Mechanism Requiring CD47 and the Integrin alpha Vbeta 3
J. Biol. Chem. 2000 275: 4796-4802. [Abstract] [Full Text] [PDF]  

Feng Lin, Deborah L. Blake, Isabelle Callebaut, Ilona S. Skerjanc, Lars Holmer, Michael W. McBurney, Micheline Paulin-Levasseur, and Howard J. Worman
MAN1, an Inner Nuclear Membrane Protein That Shares the LEM Domain with Lamina-associated Polypeptide 2 and Emerin
J. Biol. Chem. 2000 275: 4840-4847. [Abstract] [Full Text] [PDF]  

Yoshiaki Azuma, Keisuke Kaji, Rei Katogi, Sunao Takeshita, and Akira Kudo
Tumor Necrosis Factor-alpha Induces Differentiation of and Bone Resorption by Osteoclasts
J. Biol. Chem. 2000 275: 4858-4864. [Abstract] [Full Text] [PDF]  

Zhaoping Yan, Kotha Subbaramaiah, Tura Camilli, Fan Zhang, Tadashi Tanabe, Timothy A. McCaffrey, Andrew J. Dannenberg, and Babette B. Weksler
Benzo[a]pyrene Induces the Transcription of Cyclooxygenase-2 in Vascular Smooth Muscle Cells. EVIDENCE FOR THE INVOLVEMENT OF EXTRACELLULAR SIGNAL-REGULATED KINASE AND NF-kappa B
J. Biol. Chem. 2000 275: 4949-4955. [Abstract] [Full Text] [PDF]  

Roy Zent, Csilla A. Fenczik, David A. Calderwood, Shouchun Liu, Melissa Dellos, and Mark H. Ginsberg
Class- and Splice Variant-specific Association of CD98 with Integrin beta  Cytoplasmic Domains
J. Biol. Chem. 2000 275: 5059-5064. [Abstract] [Full Text] [PDF]  

Heiko Lickert, Andreas Bauer, Rolf Kemler, and Jörg Stappert
Casein Kinase II Phosphorylation of E-cadherin Increases E-cadherin/beta -Catenin Interaction and Strengthens Cell-Cell Adhesion
J. Biol. Chem. 2000 275: 5090-5095. [Abstract] [Full Text] [PDF]  

Boon Tin Chua, Ke Guo, and Peng Li
Direct Cleavage by the Calcium-activated Protease Calpain Can Lead to Inactivation of Caspases
J. Biol. Chem. 2000 275: 5131-5135. [Abstract] [Full Text] [PDF]  

Michael R. Bubb, Ilan Spector, Bret B. Beyer, and Katina M. Fosen
Effects of Jasplakinolide on the Kinetics of Actin Polymerization. AN EXPLANATION FOR CERTAIN IN VIVO OBSERVATIONS
J. Biol. Chem. 2000 275: 5163-5170. [Abstract] [Full Text] [PDF]  

Bingcheng Wang, June X. Zou, Barbro Ek-Rylander, and Erkki Ruoslahti
R-Ras Contains a Proline-rich Site That Binds to SH3 Domains and Is Required for Integrin Activation by R-Ras
J. Biol. Chem. 2000 275: 5222-5227. [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Dahu Chen, Xueping Xu, Li-Ji Zhu, Maarit Angervo, Quanxi Li, Milan K. Bagchi, and Indrani C. Bagchi
Cloning and uterus/oviduct-specific expression of a novel estrogen-regulated gene (ERG1).
J. Biol. Chem. 2000 275: 5248. [Full Text] [PDF]  


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