JBC Focus on PI3-Kinase with Echelon
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Table of Contents: Mar 3 2000; 275 (9)   [Index by Author]       Other Issues:  
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       Protein Synthesis Post-Translation Modification and Degradation
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Accelerated Publications:

Sujatha Jayaraman, Peter Haggie, Rebekka M. Wachter, S. James Remington, and A. S. Verkman
Mechanism and Cellular Applications of a Green Fluorescent Protein-based Halide Sensor
J. Biol. Chem. 2000 275: 6047-6050. [Abstract] [Full Text] [PDF]  

Zhiqiang Zou, Chunling Gao, Akhilesh K. Nagaich, Theresa Connell, Shin'ichi Saito, Judd W. Moul, Prem Seth, Ettore Appella, and Shiv Srivastava
p53 Regulates the Expression of the Tumor Suppressor Gene Maspin
J. Biol. Chem. 2000 275: 6051-6054. [Abstract] [Full Text] [PDF]  

Gary G. Chiang and Bartholomew M. Sefton
Phosphorylation of a Src Kinase at the Autophosphorylation Site in the Absence of Src Kinase Activity
J. Biol. Chem. 2000 275: 6055-6058. [Abstract] [Full Text] [PDF]  

Li-Wha Wu, Lindsey D. Mayo, James D. Dunbar, Kelly M. Kessler, Osman Nidai Ozes, Robert S. Warren, and David B. Donner
VRAP Is an Adaptor Protein That Binds KDR, a Receptor for Vascular Endothelial Cell Growth Factor
J. Biol. Chem. 2000 275: 6059-6062. [Abstract] [Full Text] [PDF]  

De-Min Zhu, Ephrem Tekle, Charles Y. Huang, and P. Boon Chock
Inositol Tetrakisphosphate as a Frequency Regulator in Calcium Oscillations in HeLa Cells
J. Biol. Chem. 2000 275: 6063-6066. [Abstract] [Full Text] [PDF]  

Kelvin Cain, Shawn B. Bratton, Claudia Langlais, Gail Walker, David G. Brown, Xiao-Ming Sun, and Gerald M. Cohen
Apaf-1 Oligomerizes into Biologically Active ~700-kDa and Inactive ~1.4-MDa Apoptosome Complexes
J. Biol. Chem. 2000 275: 6067-6070. [Abstract] [Full Text] [PDF]  

Luis M. Schang, Gwo-Jinn H. Hwang, Brian D. Dynlacht, David W. Speicher, Andrew Bantly, Priscilla A. Schaffer, Ali Shilatifard, Hui Ge, and Ramin Shiekhattar
Human PC4 Is a Substrate-specific Inhibitor of RNA Polymerase II Phosphorylation
J. Biol. Chem. 2000 275: 6071-6074. [Abstract] [Full Text] [PDF]  


DNA: Replication Repair and Recombination:

Beverly M. Orozco, Ling-Jie Kong, Lou Ann Batts, Sharon Elledge, and Linda Hanley-Bowdoin
The Multifunctional Character of a Geminivirus Replication Protein Is Reflected by Its Complex Oligomerization Properties
J. Biol. Chem. 2000 275: 6114-6122. [Abstract] [Full Text] [PDF]  

Biing Yuan Lin, Tianlin Ma, Jen-Sing Liu, Shu-Ru Kuo, Ge Jin, Thomas R. Broker, J. Wade Harper, and Louise T. Chow
HeLa Cells Are Phenotypically Limiting in Cyclin E/CDK2 for Efficient Human Papillomavirus DNA Replication
J. Biol. Chem. 2000 275: 6167-6174. [Abstract] [Full Text] [PDF]  

Yukinobu Arata, Masatoshi Fujita, Kiyoshi Ohtani, Sho Kijima, and Jun-ya Kato
Cdk2-dependent and -independent Pathways in E2F-mediated S Phase Induction
J. Biol. Chem. 2000 275: 6337-6345. [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Wataru Ishida, Toshiaki Hamamoto, Kiyoshi Kusanagi, Ken Yagi, Masahiro Kawabata, Kazuhiko Takehara, T. Kuber Sampath, Mitsuyasu Kato, and Kohei Miyazono
Smad6 Is a Smad1/5-induced Smad Inhibitor. CHARACTERIZATION OF BONE MORPHOGENETIC PROTEIN-RESPONSIVE ELEMENT IN THE MOUSE Smad6 PROMOTER
J. Biol. Chem. 2000 275: 6075-6079. [Abstract] [Full Text] [PDF]  

Jeanette M. Quinn, Paola Barraco, Mats Eriksson, and Sabeeha Merchant
Coordinate Copper- and Oxygen-responsive Cyc6 and Cpx1 Expression in Chlamydomonas Is Mediated by the Same Element
J. Biol. Chem. 2000 275: 6080-6089. [Abstract] [Full Text] [PDF]  

Arnaud Monteil, Jean Chemin, Emmanuel Bourinet, Gérard Mennessier, Philippe Lory, and Joël Nargeot
Molecular and Functional Properties of the Human alpha 1G Subunit That Forms T-type Calcium Channels
J. Biol. Chem. 2000 275: 6090-6100. [Abstract] [Full Text] [PDF]  

David J. Wadleigh, Srinivasa T. Reddy, Elizabeth Kopp, Sankar Ghosh, and Harvey R. Herschman
Transcriptional Activation of the Cyclooxygenase-2 Gene in Endotoxin-treated RAW 264.7 Macrophages
J. Biol. Chem. 2000 275: 6259-6266. [Abstract] [Full Text] [PDF]  

Wen-Shuz Yeow, Wei-Chun Au, Yuang-Taung Juang, Cindy D. Fields, Carolyn L. Dent, Dirk R. Gewert, and Paula M. Pitha
Reconstitution of Virus-mediated Expression of Interferon alpha  Genes in Human Fibroblast Cells by Ectopic Interferon Regulatory Factor-7
J. Biol. Chem. 2000 275: 6313-6320. [Abstract] [Full Text] [PDF]  

Hitoshi Shirakawa, David Landsman, Yuri V. Postnikov, and Michael Bustin
NBP-45, a Novel Nucleosomal Binding Protein with a Tissue-specific and Developmentally Regulated Expression
J. Biol. Chem. 2000 275: 6368-6374. [Abstract] [Full Text] [PDF]  

Herbert Müller-Hartmann, Heidrun Deissler, Frauke Naumann, Birgit Schmitz, Jörg Schröer, and Walter Doerfler
The Human 20-kDa 5'-(CGG)n-3'-binding Protein Is Targeted to the Nucleus and Affects the Activity of the FMR1 Promoter
J. Biol. Chem. 2000 275: 6447-6452. [Abstract] [Full Text] [PDF]  

Caroline A. Heckman, John W. Mehew, Guo-Guang Ying, Martino Introna, Josee Golay, and Linda M. Boxer
A-Myb Up-regulates Bcl-2 through a Cdx Binding Site in t(14;18) Lymphoma Cells
J. Biol. Chem. 2000 275: 6499-6508. [Abstract] [Full Text] [PDF]  

Eric Camerer, Elisabet Gjernes, Merete Wiiger, Serena Pringle, and Hans Prydz
Binding of Factor VIIa to Tissue Factor on Keratinocytes Induces Gene Expression
J. Biol. Chem. 2000 275: 6580-6585. [Abstract] [Full Text] [PDF]  

Ting-Chung Suen and Paul E. Goss
Characterization of a Repressor Element and a Juxtaposed Tissue-restricted Activator Element Located on the Distal neu Gene Promoter
J. Biol. Chem. 2000 275: 6600-6607. [Abstract] [Full Text] [PDF]  

Efrat Barnea and Yehudit Bergman
Synergy of SF1 and RAR in Activation of Oct-3/4 Promoter
J. Biol. Chem. 2000 275: 6608-6619. [Abstract] [Full Text] [PDF]  

Julie E. Trim, Satinder K. Samra, Michael J. P. Arthur, Matthew C. Wright, Martin McAulay, Raj Beri, and Derek A. Mann
Upstream Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) Element-1, a Novel and Essential Regulatory DNA Motif in the Human TIMP-1 Gene Promoter, Directly Interacts with a 30-kDa Nuclear Protein
J. Biol. Chem. 2000 275: 6657-6663. [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

Arne Heydorn, Bent O. Petersen, Jens Ø. Duus, Simon Bergmann, Trine Suhr-Jessen, and Jens Nielsen
Biosynthetic Studies of the Glycopeptide Teicoplanin by 1H and 13C NMR
J. Biol. Chem. 2000 275: 6201-6206. [Abstract] [Full Text] [PDF]  

IngMarie Nilsson, Susanne Witt, Hans Kiefer, Ismael Mingarro, and Gunnar von Heijne
Distant Downstream Sequence Determinants Can Control N-tail Translocation during Protein Insertion into the Endoplasmic Reticulum Membrane
J. Biol. Chem. 2000 275: 6207-6213. [Abstract] [Full Text] [PDF]  

Walter K. Schmidt, Amy Tam, and Susan Michaelis
Reconstitution of the Ste24p-dependent N-terminal Proteolytic Step in Yeast a-Factor Biogenesis
J. Biol. Chem. 2000 275: 6227-6233. [Abstract] [Full Text] [PDF]  

Hisato Saitoh and Joseph Hinchey
Functional Heterogeneity of Small Ubiquitin-related Protein Modifiers SUMO-1 versus SUMO-2/3
J. Biol. Chem. 2000 275: 6252-6258. [Abstract] [Full Text] [PDF]  

Rosa M. Tujebajeva, John W. Harney, and Marla J. Berry
Selenoprotein P Expression, Purification, and Immunochemical Characterization
J. Biol. Chem. 2000 275: 6288-6294. [Abstract] [Full Text] [PDF]  

Susana Rodriguez-Vilariño, Joaquín Arribas, Paz Arizti, and José G. Castaño
Proteolytic Processing and Assembly of the C5 Subunit into the Proteasome Complex
J. Biol. Chem. 2000 275: 6592-6599. [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Myung-Hee Kim, Mei Lu, Melissa Kelly, and Louis B. Hersh
Mutational Analysis of Basic Residues in the Rat Vesicular Acetylcholine Transporter. IDENTIFICATION OF A TRANSMEMBRANE ION PAIR AND EVIDENCE THAT HISTIDINE IS NOT INVOLVED IN PROTON TRANSLOCATION
J. Biol. Chem. 2000 275: 6175-6180. [Abstract] [Full Text] [PDF]  

Ann-Pascale Bijnens, Ann Gils, Isabelle Knockaert, Jan M. Stassen, and Paul J. Declerck
Importance of the Hinge Region between alpha -Helix F and the Main Part of Serpins, Based upon Identification of the Epitope of Plasminogen Activator Inhibitor Type 1 Neutralizing Antibodies
J. Biol. Chem. 2000 275: 6375-6380. [Abstract] [Full Text] [PDF]  

James J. Pitt, Elizabeth Da Silva, and Jeffrey J. Gorman
Determination of the Disulfide Bond Arrangement of Newcastle Disease Virus Hemagglutinin Neuraminidase. CORRELATION WITH A beta -SHEET PROPELLER STRUCTURAL FOLD PREDICTED FOR Paramyxoviridae ATTACHMENT PROTEINS
J. Biol. Chem. 2000 275: 6469-6478. [Abstract] [Full Text] [PDF] Supplemental Material  

Brian A. Cobb and J. Mark Petrash
Characterization of alpha -Crystallin-Plasma Membrane Binding
J. Biol. Chem. 2000 275: 6664-6672. [Abstract] [Full Text] [PDF]  

Susan Gidwitz, Suzanne Lyman, and Gilbert C. White, II
Expression and Function of Calcium Binding Domain Chimeras of the Integrins alpha IIb and alpha 5
J. Biol. Chem. 2000 275: 6680-6688. [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Timothy J. McCabe, David Fulton, Linda J. Roman, and William C. Sessa
Enhanced Electron Flux and Reduced Calmodulin Dissociation May Explain "Calcium-independent" eNOS Activation by Phosphorylation
J. Biol. Chem. 2000 275: 6123-6128. [Abstract] [Full Text] [PDF]  

Klaus Klumpp, Linh Doan, Noel A. Roberts, and Balraj Handa
RNA and DNA Hydrolysis Are Catalyzed by the Influenza Virus Endonuclease
J. Biol. Chem. 2000 275: 6181-6188. [Abstract] [Full Text] [PDF]  

Hisaaki Mihara, Tatsuo Kurihara, Tasuku Watanabe, Tohru Yoshimura, and Nobuyoshi Esaki
cDNA Cloning, Purification, and Characterization of Mouse Liver Selenocysteine Lyase. CANDIDATE FOR SELENIUM DELIVERY PROTEIN IN SELENOPROTEIN SYNTHESIS
J. Biol. Chem. 2000 275: 6195-6200. [Abstract] [Full Text] [PDF]  

Matthew J. Ryle and Lance C. Seefeldt
Hydrolysis of Nucleoside Triphosphates Other than ATP by Nitrogenase
J. Biol. Chem. 2000 275: 6214-6219. [Abstract] [Full Text] [PDF]  

Donna M. Bates, Codrina V. Popescu, Natalia Khoroshilova, Kevin Vogt, Helmut Beinert, Eckard Münck, and Patricia J. Kiley
Substitution of Leucine 28 with Histidine in the Escherichia coli Transcription Factor FNR Results in Increased Stability of the [4Fe-4S]2+ Cluster to Oxygen
J. Biol. Chem. 2000 275: 6234-6240. [Abstract] [Full Text] [PDF]  

Edwin C. J. M. de Vet, Yvonne H. A. Hilkes, Marco W. Fraaije, and Henk van den Bosch
Alkyl-dihydroxyacetonephosphate Synthase. PRESENCE AND ROLE OF FLAVIN ADENINE DINUCLEOTIDE
J. Biol. Chem. 2000 275: 6276-6283. [Abstract] [Full Text] [PDF]  

Philip A. Klenotic, Joseph L. Carlos, James C. Samuelson, Tracy A. Schuenemann, William R. Tschantz, Mark Paetzel, Natalie C. J. Strynadka, and Ross E. Dalbey
The Role of the Conserved Box E Residues in the Active Site of the Escherichia coli Type I Signal Peptidase
J. Biol. Chem. 2000 275: 6490-6498. [Abstract] [Full Text] [PDF]  

Maria L. Kireeva, Natalia Komissarova, David S. Waugh, and Mikhail Kashlev
The 8-Nucleotide-long RNA:DNA Hybrid Is a Primary Stability Determinant of the RNA Polymerase II Elongation Complex
J. Biol. Chem. 2000 275: 6530-6536. [Abstract] [Full Text] [PDF]  

Laigeng Li, Jacqueline L. Popko, Toshiaki Umezawa, and Vincent L. Chiang
5-Hydroxyconiferyl Aldehyde Modulates Enzymatic Methylation for Syringyl Monolignol Formation, a New View of Monolignol Biosynthesis in Angiosperms
J. Biol. Chem. 2000 275: 6537-6545. [Abstract] [Full Text] [PDF]  

Teijiro Aso, Katsuhisa Yamazaki, Keiko Amimoto, Asato Kuroiwa, Hideaki Higashi, Yoichi Matsuda, Shigetaka Kitajima, and Masanori Hatakeyama
Identification and Characterization of Elongin A2, a New Member of the Elongin Family of Transcription Elongation Factors, Specifically Expressed in the Testis
J. Biol. Chem. 2000 275: 6546-6552. [Abstract] [Full Text] [PDF]  

Scott W. Rowlinson, Brenda C. Crews, Douglas C. Goodwin, Claus Schneider, James K. Gierse, and Lawrence J. Marnett
Spatial Requirements for 15-(R)-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid Synthesis within the Cyclooxygenase Active Site of Murine COX-2. WHY ACETYLATED COX-1 DOES NOT SYNTHESIZE 15-(R)-HETE
J. Biol. Chem. 2000 275: 6586-6591. [Abstract] [Full Text] [PDF]  

Haruhiko Isawa, Masao Yuda, Kentaro Yoneda, and Yasuo Chinzei
The Insect Salivary Protein, Prolixin-S, Inhibits Factor IXa Generation and Xase Complex Formation in the Blood Coagulation Pathway
J. Biol. Chem. 2000 275: 6636-6641. [Abstract] [Full Text] [PDF]  

Birgitte Munch-Petersen, Wolfgang Knecht, Camilla Lenz, Leif Søndergaard, and Jure Piskur
Functional Expression of a Multisubstrate Deoxyribonucleoside Kinase from Drosophila melanogaster and Its C-terminal Deletion Mutants
J. Biol. Chem. 2000 275: 6673-6679. [Abstract] [Full Text] [PDF]  

Steven E. Screen and Raymond J. St. Leger
Cloning, Expression, and Substrate Specificity of a Fungal Chymotrypsin. EVIDENCE FOR LATERAL GENE TRANSFER FROM AN ACTINOMYCETE BACTERIUM
J. Biol. Chem. 2000 275: 6689-6694. [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Julie H. Cieslar and Geoffrey P. Dobson
Free [ADP] and Aerobic Muscle Work Follow at Least Second Order Kinetics in Rat Gastrocnemius in Vivo
J. Biol. Chem. 2000 275: 6129-6134. [Abstract] [Full Text] [PDF]  

Sangwon Kim and Prem Ponka
Effects of Interferon-gamma and Lipopolysaccharide on Macrophage Iron Metabolism Are Mediated by Nitric Oxide-induced Degradation of Iron Regulatory Protein 2
J. Biol. Chem. 2000 275: 6220-6226. [Abstract] [Full Text] [PDF]  

Sung-Kwon Jung, Lisa M. Kauri, Wei-Jun Qian, and Robert T. Kennedy
Correlated Oscillations in Glucose Consumption, Oxygen Consumption, and Intracellular Free Ca2+ in Single Islets of Langerhans
J. Biol. Chem. 2000 275: 6642-6650. [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Prateek Lala, Shinya Ito, and Clifford A. Lingwood
Retroviral Transfection of Madin-Darby Canine Kidney Cells with Human MDR1 Results in a Major Increase in Globotriaosylceramide and 105- to 106-Fold Increased Cell Sensitivity to Verocytotoxin. ROLE OF P-GLYCOPROTEIN IN GLYCOLIPID SYNTHESIS
J. Biol. Chem. 2000 275: 6246-6251. [Abstract] [Full Text] [PDF]  

Michael T. Bayliss, Sarah Howat, Catherine Davidson, and Jayesh Dudhia
The Organization of Aggrecan in Human Articular Cartilage. EVIDENCE FOR AGE-RELATED CHANGES IN THE RATE OF AGGREGATION OF NEWLY SYNTHESIZED MOLECULES
J. Biol. Chem. 2000 275: 6321-6327. [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Olaf Kruse, Ben Hankamer, Carsten Konczak, Christoph Gerle, Ed Morris, Alfons Radunz, Georg H. Schmid, and James Barber
Phosphatidylglycerol Is Involved in the Dimerization of Photosystem II
J. Biol. Chem. 2000 275: 6509-6514. [Abstract] [Full Text] [PDF]  

Hiroharu Kataoka, Noriaki Kume, Susumu Miyamoto, Manabu Minami, Takatoshi Murase, Tatsuya Sawamura, Tomoh Masaki, Nobuo Hashimoto, and Toru Kita
Biosynthesis and Post-translational Processing of Lectin-like Oxidized Low Density Lipoprotein Receptor-1 (LOX-1). N-LINKED GLYCOSYLATION AFFECTS CELL-SURFACE EXPRESSION AND LIGAND BINDING
J. Biol. Chem. 2000 275: 6573-6579. [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Cynthia A. Saraceni-Richards and Stuart B. Levy
Evidence for Interactions between Helices 5 and 8 and a Role for the Interdomain Loop in Tetracycline Resistance Mediated by Hybrid Tet Proteins
J. Biol. Chem. 2000 275: 6101-6106. [Abstract] [Full Text] [PDF]  

L. H. Jiang, D. J. Gawler, N. Hodson, C. J. Milligan, H. A. Pearson, V. Porter, and D. Wray
Regulation of Cloned Cardiac L-type Calcium Channels by cGMP-dependent Protein Kinase
J. Biol. Chem. 2000 275: 6135-6143. [Abstract] [Full Text] [PDF]  

Pierre Bonnafous and Toon Stegmann
Membrane Perturbation and Fusion Pore Formation in Influenza Hemagglutinin-mediated Membrane Fusion. A NEW MODEL FOR FUSION
J. Biol. Chem. 2000 275: 6160-6166. [Abstract] [Full Text] [PDF]  

Carmen de la Horra, Nati Hernando, Georg Lambert, Ian Forster, Jürg Biber, and Heini Murer
Molecular Determinants of pH Sensitivity of the Type IIa Na/Pi Cotransporter
J. Biol. Chem. 2000 275: 6284-6287. [Abstract] [Full Text] [PDF]  

Elöd Z. Szabó, Masayuki Numata, Gary E. Shull, and John Orlowski
Kinetic and Pharmacological Properties of Human Brain Na+/H+ Exchanger Isoform 5 Stably Expressed in Chinese Hamster Ovary Cells
J. Biol. Chem. 2000 275: 6302-6307. [Abstract] [Full Text] [PDF]  

Roy R. L. Gerona, Eric C. Larsen, Judith A. Kowalchyk, and Thomas F. J. Martin
The C Terminus of SNAP25 Is Essential for Ca2+-dependent Binding of Synaptotagmin to SNARE Complexes
J. Biol. Chem. 2000 275: 6328-6336. [Abstract] [Full Text] [PDF]  

Wataru Nunomura, Yuichi Takakuwa, Marilyn Parra, John G. Conboy, and Narla Mohandas
Ca2+-dependent and Ca2+-independent Calmodulin Binding Sites in Erythrocyte Protein 4.1. IMPLICATIONS FOR REGULATION OF PROTEIN 4.1 INTERACTIONS WITH TRANSMEMBRANE PROTEINS
J. Biol. Chem. 2000 275: 6360-6367. [Abstract] [Full Text] [PDF]  

Matthew T. Drake, Maureen A. Downs, and Linton M. Traub
Epsin Binds to Clathrin by Associating Directly with the Clathrin-terminal Domain. EVIDENCE FOR COOPERATIVE BINDING THROUGH TWO DISCRETE SITES
J. Biol. Chem. 2000 275: 6479-6489. [Abstract] [Full Text] [PDF]  

Yukio Kawamura, Keita Arakawa, Masayoshi Maeshima, and Shizuo Yoshida
Tissue Specificity of E Subunit Isoforms of Plant Vacuolar H+-ATPase and Existence of Isotype Enzymes
J. Biol. Chem. 2000 275: 6515-6522. [Abstract] [Full Text] [PDF]  

Norihiro Nakamura, Akitsugu Yamamoto, Yoh Wada, and Masamitsu Futai
Syntaxin 7 Mediates Endocytic Trafficking to Late Endosomes
J. Biol. Chem. 2000 275: 6523-6529. [Abstract] [Full Text] [PDF]  

Ralf Jacob, Marwan Alfalah, Jürgen Grünberg, Maik Obendorf, and Hassan Y. Naim
Structural Determinants Required for Apical Sorting of an Intestinal Brush-border Membrane Protein
J. Biol. Chem. 2000 275: 6566-6572. [Abstract] [Full Text] [PDF]  

Kota Sato, Mutsumi Inaba, Yuki Suwa, Aya Matsuu, Yoshiaki Hikasa, Ken-ichiro Ono, and Katsumoto Kagota
Inherited Defects of Sodium-dependent Glutamate Transport Mediated by Glutamate/Aspartate Transporter in Canine Red Cells Due to a Decreased Level of Transporter Protein Expression
J. Biol. Chem. 2000 275: 6620-6627. [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Sandrine Bastian, Didier Pruneau, Bruno Loillier, Claude Robert, Jean-Claude Bonnafous, and Jean-Luc Paquet
Identification of a Key Region of Kinin B1 Receptor for High Affinity Binding of Peptide Antagonists
J. Biol. Chem. 2000 275: 6107-6113. [Abstract] [Full Text] [PDF]  

Russell I. Ludowyke, Jeff Holst, Lisa-Maree Mudge, and Alistair T. R. Sim
Transient Translocation and Activation of Protein Phosphatase 2A during Mast Cell Secretion
J. Biol. Chem. 2000 275: 6144-6152. [Abstract] [Full Text] [PDF]  

John J. LaPres, Edward Glover, Elizabeth E. Dunham, Maureen K. Bunger, and Christopher A. Bradfield
ARA9 Modifies Agonist Signaling through an Increase in Cytosolic Aryl Hydrocarbon Receptor
J. Biol. Chem. 2000 275: 6153-6159. [Abstract] [Full Text] [PDF]  

Kristina Sachs, Dieter Maretzki, Christoph K. Meyer, and Klaus Peter Hofmann
Diffusible Ligand All-trans-retinal Activates Opsin via a Palmitoylation-dependent Mechanism
J. Biol. Chem. 2000 275: 6189-6194. [Abstract] [Full Text] [PDF]  

Hidehisa Yoshimura, Toru Hisabori, Shuichi Yanagisawa, and Masayuki Ohmori
Identification and Characterization of a Novel cAMP Receptor Protein in the Cyanobacterium Synechocystis sp. PCC 6803
J. Biol. Chem. 2000 275: 6241-6245. [Abstract] [Full Text] [PDF]  

Masahiro Aoki, Christian Schetter, Martin Himly, Osvaldo Batista, Hwai Wen Chang, and Peter K. Vogt
The Catalytic Subunit of Phosphoinositide 3-Kinase: Requirements for Oncogenicity
J. Biol. Chem. 2000 275: 6267-6275. [Abstract] [Full Text] [PDF]  

Asael Herman, Christophe Bignon, Nathalie Daniel, Jeanne Grosclaude, Arieh Gertler, and Jean Djiane
Functional Heterodimerization of Prolactin and Growth Hormone Receptors by Ovine Placental Lactogen
J. Biol. Chem. 2000 275: 6295-6301. [Abstract] [Full Text] [PDF]  

Mónica R. Calera, Gino Vallega, and Paul F. Pilch
Dynamics of Protein-tyrosine Phosphatases in Rat Adipocytes
J. Biol. Chem. 2000 275: 6308-6312. [Abstract] [Full Text] [PDF]  

Silvia Pfeiffer, Kurt Schmidt, and Bernd Mayer
Dityrosine Formation Outcompetes Tyrosine Nitration at Low Steady-state Concentrations of Peroxynitrite. IMPLICATIONS FOR TYROSINE MODIFICATION BY NITRIC OXIDE/SUPEROXIDE IN VIVO
J. Biol. Chem. 2000 275: 6346-6352. [Abstract] [Full Text] [PDF]  

Scott E. Jarvis, Johanna M. Magga, Aaron M. Beedle, Janice E. A. Braun, and Gerald W. Zamponi
G Protein Modulation of N-type Calcium Channels Is Facilitated by Physical Interactions between Syntaxin 1A and Gbeta gamma
J. Biol. Chem. 2000 275: 6388-6394. [Abstract] [Full Text] [PDF]  

Akira Sakakibara and Seisuke Hattori
Chat, a Cas/HEF1-associated Adaptor Protein That Integrates Multiple Signaling Pathways
J. Biol. Chem. 2000 275: 6404-6410. [Abstract] [Full Text] [PDF]  

Benoit Poulin, Fujio Sekiya, and Sue Goo Rhee
Differential Roles of the Src Homology 2 Domains of Phospholipase C-gamma 1 (PLC-gamma 1) in Platelet-derived Growth Factor-induced Activation of PLC-gamma 1 in Intact Cells
J. Biol. Chem. 2000 275: 6411-6416. [Abstract] [Full Text] [PDF]  

Thottala Jayaraman and Andrew R. Marks
Calcineurin Is Downstream of the Inositol 1,4,5-Trisphosphate Receptor in the Apoptotic and Cell Growth Pathways
J. Biol. Chem. 2000 275: 6417-6420. [Abstract] [Full Text] [PDF]  

Florian Kühnel, Lars Zender, Yasmin Paul, Maja K. Tietze, Christian Trautwein, Michael Manns, and Stefan Kubicka
NFkappa B Mediates Apoptosis through Transcriptional Activation of Fas (CD95) in Adenoviral Hepatitis
J. Biol. Chem. 2000 275: 6421-6427. [Abstract] [Full Text] [PDF]  

Tetsuya Furuya, Corinna Kashuba, Roberto Docampo, and Silvia N. J. Moreno
A Novel Phosphatidylinositol-Phospholipase C of Trypanosoma cruzi That Is Lipid Modified and Activated during Trypomastigote to Amastigote Differentiation
J. Biol. Chem. 2000 275: 6428-6438. [Abstract] [Full Text] [PDF]  

Robert Brenner, Tim J. Jegla, Alan Wickenden, Yi Liu, and Richard W. Aldrich
Cloning and Functional Characterization of Novel Large Conductance Calcium-activated Potassium Channel beta  Subunits, hKCNMB3 and hKCNMB4
J. Biol. Chem. 2000 275: 6453-6461. [Abstract] [Full Text] [PDF]  

Yao-Qi Huang, Jian-Jun Li, and Simon Karpatkin
Thrombin Inhibits Tumor Cell Growth in Association with Up-regulation of p21waf/cip1 and Caspases via a p53-independent, STAT-1-dependent Pathway
J. Biol. Chem. 2000 275: 6462-6468. [Abstract] [Full Text] [PDF]  

José Vázquez-Prado, Luz del Carmen Medina, María Teresa Romero-Avila, Claudia González-Espinosa, and J. Adolfo García-Sáinz
Norepinephrine- and Phorbol Ester-induced Phosphorylation of alpha 1a-Adrenergic Receptors. FUNCTIONAL ASPECTS
J. Biol. Chem. 2000 275: 6553-6559. [Abstract] [Full Text] [PDF]  

Mourad Majidi, J. Silvio Gutkind, and Jack H. Lichy
Deletion of the COOH Terminus Converts the ST5 p70 Protein from an Inhibitor of RAS Signaling to an Activator with Transforming Activity in NIH-3T3 Cells
J. Biol. Chem. 2000 275: 6560-6565. [Abstract] [Full Text] [PDF]  

Kevin D. Brown, Tamara A. Lataxes, Sanjeev Shangary, Jennifer L. Mannino, Jason F. Giardina, Jiandong Chen, and R. Baskaran
Ionizing Radiation Exposure Results in Up-regulation of Ku70 via a p53/Ataxia-Telangiectasia-mutated Protein-dependent Mechanism
J. Biol. Chem. 2000 275: 6651-6656. [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Snezana Milutinovic, J. David Knox, and Moshe Szyf
DNA Methyltransferase Inhibition Induces the Transcription of the Tumor Suppressor p21WAF1/CIP1/sdi1
J. Biol. Chem. 2000 275: 6353-6359. [Abstract] [Full Text] [PDF]  

Michael T. Chin, Koji Maemura, Shinya Fukumoto, Mukesh K. Jain, Matthew D. Layne, Masafumi Watanabe, Chung-Ming Hsieh, and Mu-En Lee
Cardiovascular Basic Helix Loop Helix Factor 1, a Novel Transcriptional Repressor Expressed Preferentially in the Developing and Adult Cardiovascular System
J. Biol. Chem. 2000 275: 6381-6387. [Abstract] [Full Text] [PDF]  

Peter Penzes, Richard C. Johnson, M. Rashid Alam, Vikram Kambampati, Richard E. Mains, and Betty A. Eipper
An Isoform of Kalirin, a Brain-specific GDP/GTP Exchange Factor, Is Enriched in the Postsynaptic Density Fraction
J. Biol. Chem. 2000 275: 6395-6403. [Abstract] [Full Text] [PDF]  

Yasuo Okamoto, Haruaki Ninomiya, Soichi Miwa, and Tomoh Masaki
Cholesterol Oxidation Switches the Internalization Pathway of Endothelin Receptor Type A from Caveolae to Clathrin-coated Pits in Chinese Hamster Ovary Cells
J. Biol. Chem. 2000 275: 6439-6446. [Abstract] [Full Text] [PDF]  

Hongmiao Sheng, Jinyi Shao, Dan A. Dixon, Christopher S. Williams, Stephen M. Prescott, Raymond N. DuBois, and R. Daniel Beauchamp
Transforming Growth Factor-beta 1 Enhances Ha-ras-induced Expression of Cyclooxygenase-2 in Intestinal Epithelial Cells via Stabilization of mRNA
J. Biol. Chem. 2000 275: 6628-6635. [Abstract] [Full Text] [PDF]  


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