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Table of Contents: May 3 2002; 277 (18)   [Index by Author] 
[Cover Figure and Caption]
      Down Classics
      Down Accelerated Publications
      Down DNA: Replication, Repair, and Recombination
      Down Genes: Structure and Regulation
      Down RNA: Structure, Metabolism, and Catalysis
      Down Protein Synthesis, Post-Translation Modification, and Degradation
      Down Genomics, Proteomics, and Bioinformatics
      Down Protein Structure and Folding
      Down Enzyme Catalysis and Regulation
      Down Metabolism and Bioenergetics
      Down Glycobiology and Extracellular Matrices
      Down Lipids and Lipoproteins
      Down Membrane Transport, Structure, Function, and Biogenesis
      Down Mechanisms Of Signal Transduction
      Down Molecular Basis Of Cell and Developmental Biology
      Down Additions and Corrections
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Classics:Back

Robert D. Simoni, Robert L. Hill, and Martha Vaughan
Nutritional Biochemistry and the Amino Acid Composition of Proteins: the Early Years of Protein Chemistry. The Work of Thomas B. Osborne and Lafayette B. Mendel
THE AMINO-ACID MINIMUM FOR MAINTENANCE AND GROWTH, AS EXEMPLIFIED BY FURTHER EXPERIMENTS WITH LYSINE AND TRYPTOPHANE (Thomas B. Osborne, Lafayette B. Mendel, and With the Cooperation of Edna L. Ferry and Alfred J. Wakeman J. Biol. Chem. 25, 1-12)
THE RÔLE OF VITAMINES IN THE DIET (Thomas B. Osborne, Lafayette B. Mendel, and With the cooperation of Edna L. Ferry and Alfred J. Wakeman J. Biol. Chem. 31, 149-163)
J. Biol. Chem. 2002 277: e7. [Full Text]  


Accelerated Publications:Back

Hélène Hirbec, Olga Perestenko, Atsushi Nishimune, Guido Meyer, Shigetada Nakanishi, Jeremy M. Henley, and Kumlesh K. Dev
The PDZ Proteins PICK1, GRIP, and Syntenin Bind Multiple Glutamate Receptor Subtypes. ANALYSIS OF PDZ BINDING MOTIFS
J. Biol. Chem. 2002 277: 15221-15224. First Published on March 12, 2002; doi:10.1074/jbc.C200112200 [Abstract] [Full Text] [PDF]  

Mikhail V. Ponamarev, Matthew J. Longley, Dinh Nguyen, Thomas A. Kunkel, and William C. Copeland
Active Site Mutation in DNA Polymerase gamma Associated with Progressive External Ophthalmoplegia Causes Error-prone DNA Synthesis
J. Biol. Chem. 2002 277: 15225-15228. First Published on March 15, 2002; doi:10.1074/jbc.C200100200 [Abstract] [Full Text] [PDF]  

Mio Kawaguchi, Luiz F. Onuchic, and Shau-Ku Huang
Activation of Extracellular Signal-regulated Kinase (ERK)1/2, but Not p38 and c-Jun N-terminal Kinase, Is Involved in Signaling of a Novel Cytokine, ML-1
J. Biol. Chem. 2002 277: 15229-15232. First Published on March 12, 2002; doi:10.1074/jbc.C100641200 [Abstract] [Full Text] [PDF]  

Jack D. Griffith, Laura A. Lindsey-Boltz, and Aziz Sancar
Structures of the Human Rad17-Replication Factor C and Checkpoint Rad 9-1-1 Complexes Visualized by Glycerol Spray/Low Voltage Microscopy
J. Biol. Chem. 2002 277: 15233-15236. First Published on March 20, 2002; doi:10.1074/jbc.C200129200 [Abstract] [Full Text] [PDF]  

Yick-Pang Ching, Andy S. H. Pang, Wing-Ho Lam, Robert Z. Qi, and Jerry H. Wang
Identification of a Neuronal Cdk5 Activator-binding Protein as Cdk5 Inhibitor
J. Biol. Chem. 2002 277: 15237-15240. First Published on March 6, 2002; doi:10.1074/jbc.C200032200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:Back

Lajos Haracska, Satya Prakash, and Louise Prakash
Yeast Rev1 Protein Is a G Template-specific DNA Polymerase
J. Biol. Chem. 2002 277: 15546-15551. First Published on February 15, 2002; doi:10.1074/jbc.M112146200 [Abstract] [Full Text] [PDF]  

Mary Lynn Tassotto and Christopher K. Mathews
Assessing the Metabolic Function of the MutT 8-Oxodeoxyguanosine Triphosphatase in Escherichia coli by Nucleotide Pool Analysis
J. Biol. Chem. 2002 277: 15807-15812. First Published on February 20, 2002; doi:10.1074/jbc.M200965200 [Abstract] [Full Text] [PDF]  

Ryusuke Tadokoro, Masako Fujita, Hitoshi Miura, Katsuhiko Shirahige, Hiroshi Yoshikawa, Toshiki Tsurimoto, and Chikashi Obuse
Scheduled Conversion of Replication Complex Architecture at Replication Origins of Saccharomyces cerevisiae during the Cell Cycle
J. Biol. Chem. 2002 277: 15881-15889. First Published on February 12, 2002; doi:10.1074/jbc.M200322200 [Abstract] [Full Text] [PDF]  

Naoko Takahashi, Shinji Tsutsumi, Tomofusa Tsuchiya, Bruce Stillman, and Tohru Mizushima
Functions of Sensor 1 and Sensor 2 Regions of Saccharomyces cerevisiae Cdc6p in Vivo and in Vitro
J. Biol. Chem. 2002 277: 16033-16040. First Published on February 4, 2002; doi:10.1074/jbc.M108615200 [Abstract] [Full Text] [PDF]  

Steve M. Patrick and John J. Turchi
Xeroderma Pigmentosum Complementation Group A Protein (XPA) Modulates RPA-DNA Interactions via Enhanced Complex Stability and Inhibition of Strand Separation Activity
J. Biol. Chem. 2002 277: 16096-16101. First Published on February 21, 2002; doi:10.1074/jbc.M200816200 [Abstract] [Full Text] [PDF]  

N. Guhan and K. Muniyappa
Mycobacterium tuberculosis RecA Intein Possesses a Novel ATP-dependent Site-specific Double-stranded DNA Endonuclease Activity
J. Biol. Chem. 2002 277: 16257-16264. First Published on February 15, 2002; doi:10.1074/jbc.M112365200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:Back

Alison J. Pollard, Adrian R. Krainer, Stephen C. Robson, and G. Nicholas Europe-Finner
Alternative Splicing of the Adenylyl Cyclase Stimulatory G-protein Galpha s Is Regulated by SF2/ASF and Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNPA1) and Involves the Use of an Unusual TG 3'-Splice Site
J. Biol. Chem. 2002 277: 15241-15251. First Published on February 1, 2002; doi:10.1074/jbc.M109046200 [Abstract] [Full Text] [PDF]  

Christophe Beloin, Sorcha McKenna, and Charles J. Dorman
Molecular Dissection of VirB, a Key Regulator of the Virulence Cascade of Shigella flexneri
J. Biol. Chem. 2002 277: 15333-15344. First Published on February 15, 2002; doi:10.1074/jbc.M111429200 [Abstract] [Full Text] [PDF]  

Motoki Susa, Ranjan Sen, and Nobuo Shimamoto
Generality of the Branched Pathway in Transcription Initiation by Escherichia coli RNA Polymerase
J. Biol. Chem. 2002 277: 15407-15412. First Published on February 19, 2002; doi:10.1074/jbc.M112481200 [Abstract] [Full Text] [PDF]  

Sanchari Kar, Kazuyasu Sakaguchi, Yasuyuki Shimohigashi, Soma Samaddar, Raja Banerjee, Gautam Basu, V. Swaminathan, Tapas K. Kundu, and Siddhartha Roy
Effect of Phosphorylation on the Structure and Fold of Transactivation Domain of p53
J. Biol. Chem. 2002 277: 15579-15585. First Published on February 19, 2002; doi:10.1074/jbc.M106915200 [Abstract] [Full Text] [PDF]  

Manuel Baader, Carmela Gnerre, John J. Stegeman, and Urs A. Meyer
Transcriptional Activation of Cytochrome P450 CYP2C45 by Drugs Is Mediated by the Chicken Xenobiotic Receptor (CXR) Interacting with a Phenobarbital Response Enhancer Unit
J. Biol. Chem. 2002 277: 15647-15653. First Published on February 26, 2002; doi:10.1074/jbc.M109882200 [Abstract] [Full Text] [PDF]  

Osamu Sato, Chikako Kuriki, Yuka Fukui, and Kiyoto Motojima
Dual Promoter Structure of Mouse and Human Fatty Acid Translocase/CD36 Genes and Unique Transcriptional Activation by Peroxisome Proliferator-activated Receptor alpha and gamma Ligands
J. Biol. Chem. 2002 277: 15703-15711. First Published on February 26, 2002; doi:10.1074/jbc.M110158200 [Abstract] [Full Text] [PDF]  

Fabienne Rajas, Amandine Gautier, Isabelle Bady, Sandrine Montano, and Gilles Mithieux
Polyunsaturated Fatty Acyl Coenzyme A Suppress the Glucose-6-phosphatase Promoter Activity by Modulating the DNA Binding of Hepatocyte Nuclear Factor 4alpha
J. Biol. Chem. 2002 277: 15736-15744. First Published on February 25, 2002; doi:10.1074/jbc.M200971200 [Abstract] [Full Text] [PDF]  

Reiko Akakura and Stephen C. Winans
Mutations in the occQ Operator That Decrease OccR-induced DNA Bending Do Not Cause Constitutive Promoter Activity
J. Biol. Chem. 2002 277: 15773-15780. First Published on February 27, 2002; doi:10.1074/jbc.M200109200 [Abstract] [Full Text] [PDF]  

Taketoshi Mizutani, Taiji Ito, Mitsue Nishina, Nobutake Yamamichi, Akiko Watanabe, and Hideo Iba
Maintenance of Integrated Proviral Gene Expression Requires Brm, a Catalytic Subunit of SWI/SNF Complex
J. Biol. Chem. 2002 277: 15859-15864. First Published on February 15, 2002; doi:10.1074/jbc.M112421200 [Abstract] [Full Text] [PDF]  

Sarmila Majumder, Kalpana Ghoshal, Jharna Datta, Shoumei Bai, Xiaocheng Dong, Ning Quan, Christoph Plass, and Samson T. Jacob
Role of de Novo DNA Methyltransferases and Methyl CpG-binding Proteins in Gene Silencing in a Rat Hepatoma
J. Biol. Chem. 2002 277: 16048-16058. First Published on February 13, 2002; doi:10.1074/jbc.M111662200 [Abstract] [Full Text] [PDF]  

Kitti Torrungruang, Marta Alvarez, Rita Shah, Jude E. Onyia, Simon J. Rhodes, and Joseph P. Bidwell
DNA Binding and Gene Activation Properties of the Nmp4 Nuclear Matrix Transcription Factors
J. Biol. Chem. 2002 277: 16153-16159. First Published on February 26, 2002; doi:10.1074/jbc.M107496200 [Abstract] [Full Text] [PDF]  

Nicholas E. S. Sibinga, Mark W. Feinberg, Hongyuan Yang, Frank Werner, and Mukesh K. Jain
Macrophage-restricted and Interferon gamma -inducible Expression of the Allograft Inflammatory Factor-1 Gene Requires Pu.1
J. Biol. Chem. 2002 277: 16202-16210. First Published on February 22, 2002; doi:10.1074/jbc.M200935200 [Abstract] [Full Text] [PDF]  

Heather A. Foley, Solomon F. Ofori-Acquah, Akihiko Yoshimura, Stuart Critz, B. Surendra Baliga, and Betty S. Pace
Stat3beta Inhibits gamma -Globin Gene Expression in Erythroid Cells
J. Biol. Chem. 2002 277: 16211-16219. First Published on February 20, 2002; doi:10.1074/jbc.M106556200 [Abstract] [Full Text] [PDF]  

Kumar Pandya and Tim M. Townes
Basic Residues within the Kruppel Zinc Finger DNA Binding Domains Are the Critical Nuclear Localization Determinants of EKLF/KLF-1
J. Biol. Chem. 2002 277: 16304-16312. First Published on February 13, 2002; doi:10.1074/jbc.M200866200 [Abstract] [Full Text] [PDF]  


RNA: Structure, Metabolism, and Catalysis:Back

Susanne Schneider, Hans-Rudolf Hotz, and Beate Schwer
Characterization of Dominant-negative Mutants of the DEAH-box Splicing Factors Prp22 and Prp16
J. Biol. Chem. 2002 277: 15452-15458. First Published on February 20, 2002; doi:10.1074/jbc.M112473200 [Abstract] [Full Text] [PDF]  

Andrea Lapucci, Martino Donnini, Laura Papucci, Ewa Witort, Alessio Tempestini, Anna Bevilacqua, Angelo Nicolin, Gary Brewer, Nicola Schiavone, and Sergio Capaccioli
AUF1 Is a bcl-2 A + U-rich Element-binding Protein Involved in bcl-2 mRNA Destabilization during Apoptosis
J. Biol. Chem. 2002 277: 16139-16146. First Published on February 20, 2002; doi:10.1074/jbc.M201377200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:Back

Søren Kahns, Simon Lykkebo, Lene Diness Jakobsen, Morten S. Nielsen, and Poul Henning Jensen
Caspase-mediated Parkin Cleavage in Apoptotic Cell Death
J. Biol. Chem. 2002 277: 15303-15308. First Published on February 11, 2002; doi:10.1074/jbc.M111534200 [Abstract] [Full Text] [PDF]  

Ming-Kai Chern, Kwang-Ning Chang, Li-Fan Liu, Tsuey-Chyi S. Tam, Yi-Chen Liu, Yi-Lin Liang, and Ming F. Tam
Yeast Ribosomal Protein L12 Is a Substrate of Protein-arginine Methyltransferase 2
J. Biol. Chem. 2002 277: 15345-15353. First Published on February 20, 2002; doi:10.1074/jbc.M111379200 [Abstract] [Full Text] [PDF]  

Sheau-Fen Lee, Chiung-Yuan Ko, Chin-Tien Wang, and Steve S.-L. Chen
Effect of Point Mutations in the N Terminus of the Lentivirus Lytic Peptide-1 Sequence of Human Immunodeficiency Virus Type 1 Transmembrane Protein gp41 on Env Stability
J. Biol. Chem. 2002 277: 15363-15375. First Published on February 21, 2002; doi:10.1074/jbc.M201479200 [Abstract] [Full Text] [PDF]  

Andrey V. Pisarev, Maksim A. Skabkin, Adri A. Thomas, William C. Merrick, Lev P. Ovchinnikov, and Ivan N. Shatsky
Positive and Negative Effects of the Major Mammalian Messenger Ribonucleoprotein p50 on Binding of 40 S Ribosomal Subunits to the Initiation Codon of beta -Globin mRNA
J. Biol. Chem. 2002 277: 15445-15451. First Published on February 19, 2002; doi:10.1074/jbc.M111954200 [Abstract] [Full Text] [PDF]  

Ziyin Li, Chun-Bin Zou, Yi Yao, Martin A. Hoyt, Stephen McDonough, Zachary B. Mackey, Philip Coffino, and Ching C. Wang
An Easily Dissociated 26 S Proteasome Catalyzes an Essential Ubiquitin-mediated Protein Degradation Pathway in Trypanosoma brucei
J. Biol. Chem. 2002 277: 15486-15498. First Published on February 19, 2002; doi:10.1074/jbc.M109029200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Amnon Golan, Yana Yudkovsky, and Avram Hershko
The Cyclin-Ubiquitin Ligase Activity of Cyclosome/APC Is Jointly Activated by Protein Kinases Cdk1-Cyclin B and Plk
J. Biol. Chem. 2002 277: 15552-15557. First Published on February 21, 2002; doi:10.1074/jbc.M111476200 [Abstract] [Full Text] [PDF]  

Linda E. Hyman, Edward Kwon, Sumana Ghosh, Jennifer McGee, Anna M. Boguszewska Chachulska, Tanya Jackson, and William H. Baricos
Binding to Elongin C Inhibits Degradation of Interacting Proteins in Yeast
J. Biol. Chem. 2002 277: 15586-15591. First Published on February 25, 2002; doi:10.1074/jbc.M200800200 [Abstract] [Full Text] [PDF]  

Manabu Furukawa, Tomohiko Ohta, and Yue Xiong
Activation of UBC5 Ubiquitin-conjugating Enzyme by the RING Finger of ROC1 and Assembly of Active Ubiquitin Ligases by All Cullins
J. Biol. Chem. 2002 277: 15758-15765. First Published on February 22, 2002; doi:10.1074/jbc.M108565200 [Abstract] [Full Text] [PDF]  

Ying Shen, Laurent Meunier, and Linda M. Hendershot
Identification and Characterization of a Novel Endoplasmic Reticulum (ER) DnaJ Homologue, Which Stimulates ATPase Activity of BiP in Vitro and Is Induced by ER Stress
J. Biol. Chem. 2002 277: 15947-15956. First Published on February 8, 2002; doi:10.1074/jbc.M112214200 [Abstract] [Full Text] [PDF]  

Seung Hyun Yoo, Soon Hee You, Moon Kyung Kang, Yang Hoon Huh, Choong Sik Lee, and Chan Seob Shim
Localization of the Secretory Granule Marker Protein Chromogranin B in the Nucleus. POTENTIAL ROLE IN TRANSCRIPTION CONTROL
J. Biol. Chem. 2002 277: 16011-16021. First Published on February 19, 2002; doi:10.1074/jbc.M105594200 [Abstract] [Full Text] [PDF]  

Jeong-Il Oh and Samuel Kaplan
Oxygen Adaptation. THE ROLE OF THE CcoQ SUBUNIT OF THE cbb3 CYTOCHROME c OXIDASE OF RHODOBACTER SPHAEROIDES 2.4.1
J. Biol. Chem. 2002 277: 16220-16228. First Published on February 25, 2002; doi:10.1074/jbc.M200198200 [Abstract] [Full Text] [PDF]  

Adrienne M. Perry, Hung Ton-That, Sarkis K. Mazmanian, and Olaf Schneewind
Anchoring of Surface Proteins to the Cell Wall of Staphylococcus aureus. III. LIPID II IS AN IN VIVO PEPTIDOGLYCAN SUBSTRATE FOR SORTASE-CATALYZED SURFACE PROTEIN ANCHORING
J. Biol. Chem. 2002 277: 16241-16248. First Published on February 20, 2002; doi:10.1074/jbc.M109194200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:Back

Michael Motz, Ingo Kober, Charles Girardot, Eva Loeser, Ulrike Bauer, Michael Albers, Gerd Moeckel, Eric Minch, Hartmut Voss, Christian Kilger, and Manfred Koegl
Elucidation of an Archaeal Replication Protein Network to Generate Enhanced PCR Enzymes
J. Biol. Chem. 2002 277: 16179-16188. First Published on January 22, 2002; doi:10.1074/jbc.M107793200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:Back

Agustín Valenzuela-Fernández, Thierry Planchenault, Françoise Baleux, Isabelle Staropoli, Karine Le-Barillec, Dominique Leduc, Thierry Delaunay, Françoise Lazarini, Jean-Louis Virelizier, Michel Chignard, Dominique Pidard, and Fernando Arenzana-Seisdedos
Leukocyte Elastase Negatively Regulates Stromal Cell-derived Factor-1 (SDF-1)/CXCR4 Binding and Functions by Amino-terminal Processing of SDF-1 and CXCR4
J. Biol. Chem. 2002 277: 15677-15689. First Published on February 26, 2002; doi:10.1074/jbc.M111388200 [Abstract] [Full Text] [PDF]  

Simon Hellstern, Takako Sasaki, Charlotte Fauser, Ariel Lustig, Rupert Timpl, and Jürgen Engel
Functional Studies on Recombinant Domains of Mac-2-binding Protein
J. Biol. Chem. 2002 277: 15690-15696. First Published on February 26, 2002; doi:10.1074/jbc.M200386200 [Abstract] [Full Text] [PDF]  

Tomas Nyman, Rebecca Page, Clarence E. Schutt, Roger Karlsson, and Uno Lindberg
A Cross-linked Profilin-Actin Heterodimer Interferes with Elongation at the Fast-growing End of F-actin
J. Biol. Chem. 2002 277: 15828-15833. First Published on February 13, 2002; doi:10.1074/jbc.M112195200 [Abstract] [Full Text] [PDF]  

Chi-Fon Chang, Hui-Ting Chou, Jacinta L. Chuang, David T. Chuang, and Tai-huang Huang
Solution Structure and Dynamics of the Lipoic Acid-bearing Domain of Human Mitochondrial Branched-chain alpha -Keto Acid Dehydrogenase Complex
J. Biol. Chem. 2002 277: 15865-15873. First Published on February 11, 2002; doi:10.1074/jbc.M110952200 [Abstract] [Full Text] [PDF]  

Masaru Goto, Yoshitaka Nakajima, and Ken Hirotsu
Crystal Structure of Argininosuccinate Synthetase from Thermus thermophilus HB8. STRUCTURAL BASIS FOR THE CATALYTIC ACTION
J. Biol. Chem. 2002 277: 15890-15896. First Published on February 13, 2002; doi:10.1074/jbc.M112430200 [Abstract] [Full Text] [PDF]  

Lawrence J. Hayward, Jorge A. Rodriguez, Ji W. Kim, Ashutosh Tiwari, Joy J. Goto, Diane E. Cabelli, Joan Selverstone Valentine, and Robert H. Brown, Jr.
Decreased Metallation and Activity in Subsets of Mutant Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis
J. Biol. Chem. 2002 277: 15923-15931. First Published on February 19, 2002; doi:10.1074/jbc.M112087200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Jorge A. Rodriguez, Joan S. Valentine, Daryl K. Eggers, James A. Roe, Ashutosh Tiwari, Robert H. Brown, Jr., and Lawrence J. Hayward
Familial Amyotrophic Lateral Sclerosis-associated Mutations Decrease the Thermal Stability of Distinctly Metallated Species of Human Copper/Zinc Superoxide Dismutase
J. Biol. Chem. 2002 277: 15932-15937. First Published on February 19, 2002; doi:10.1074/jbc.M112088200 [Abstract] [Full Text] [PDF]  

Wim Versées, Klaas Decanniere, Els Van Holsbeke, Neel Devroede, and Jan Steyaert
Enzyme-Substrate Interactions in the Purine-specific Nucleoside Hydrolase from Trypanosoma vivax
J. Biol. Chem. 2002 277: 15938-15946. First Published on February 19, 2002; doi:10.1074/jbc.M111735200 [Abstract] [Full Text] [PDF]  

Lucas M. Velloso, Kerstin Svensson, Gunter Schneider, Ralf F. Pettersson, and Ylva Lindqvist
Crystal Structure of the Carbohydrate Recognition Domain of p58/ERGIC-53, a Protein Involved in Glycoprotein Export from the Endoplasmic Reticulum
J. Biol. Chem. 2002 277: 15979-15984. First Published on February 15, 2002; doi:10.1074/jbc.M112098200 [Abstract] [Full Text] [PDF]  

Irwan T. Makagiansar, Phuong D. Nguyen, Atsutoshi Ikesue, Krzysztof Kuczera, William Dentler, Jeffrey L. Urbauer, Nadezhda Galeva, Michail Alterman, and Teruna J. Siahaan
Disulfide Bond Formation Promotes the cis- and trans-Dimerization of the E-cadherin-derived First Repeat
J. Biol. Chem. 2002 277: 16002-16010. First Published on February 20, 2002; doi:10.1074/jbc.M200916200 [Abstract] [Full Text] [PDF]  

Natalie Golts, Heather Snyder, Mark Frasier, Catherine Theisler, Peter Choi, and Benjamin Wolozin
Magnesium Inhibits Spontaneous and Iron-induced Aggregation of alpha -Synuclein
J. Biol. Chem. 2002 277: 16116-16123. First Published on February 15, 2002; doi:10.1074/jbc.M107866200 [Abstract] [Full Text] [PDF]  

Evelin Kozma, Elaine Brown, Elizabeth M. Ellis, and Adrian J. Lapthorn
The Crystal Structure of Rat Liver AKR7A1. A DIMERIC MEMBER OF THE ALDO-KETO REDUCTASE SUPERFAMILY
J. Biol. Chem. 2002 277: 16285-16293. First Published on February 11, 2002; doi:10.1074/jbc.M110808200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:Back

Chunling Gong and Stewart Shuman
Chlorella Virus RNA Triphosphatase. MUTATIONAL ANALYSIS AND MECHANISM OF INHIBITION BY TRIPOLYPHOSPHATE
J. Biol. Chem. 2002 277: 15317-15324. First Published on February 13, 2002; doi:10.1074/jbc.M200532200 [Abstract] [Full Text] [PDF]  

Yu Lin Jiang, Alexander C. Drohat, Yoshitaka Ichikawa, and James T. Stivers
Probing the Limits of Electrostatic Catalysis by Uracil DNA Glycosylase Using Transition State Mimicry and Mutagenesis
J. Biol. Chem. 2002 277: 15385-15392. First Published on February 21, 2002; doi:10.1074/jbc.M200634200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Arno de Kreij, Bertus van den Burg, Gerard Venema, Gert Vriend, Vincent G. H. Eijsink, and Jens E. Nielsen
The Effects of Modifying the Surface Charge on the Catalytic Activity of a Thermolysin-like Protease
J. Biol. Chem. 2002 277: 15432-15438. First Published on February 21, 2002; doi:10.1074/jbc.M200807200 [Abstract] [Full Text] [PDF]  

Anu Salminen, Alexey N. Parfenyev, Krista Salli, Irina S. Efimova, Natalia N. Magretova, Adrian Goldman, Alexander A. Baykov, and Reijo Lahti
Modulation of Dimer Stability in Yeast Pyrophosphatase by Mutations at the Subunit Interface and Ligand Binding to the Active Site
J. Biol. Chem. 2002 277: 15465-15471. First Published on February 19, 2002; doi:10.1074/jbc.M200101200 [Abstract] [Full Text] [PDF]  

Scott W. Nelson, Richard B. Honzatko, and Herbert J. Fromm
Hybrid Tetramers of Porcine Liver Fructose-1,6-bisphosphatase Reveal Multiple Pathways of Allosteric Inhibition
J. Biol. Chem. 2002 277: 15539-15545. First Published on February 19, 2002; doi:10.1074/jbc.M112304200 [Abstract] [Full Text] [PDF]  

Emanuelle Pascolo, Christian Wenz, Joachim Lingner, Norbert Hauel, Henning Priepke, Iris Kauffmann, Pilar Garin-Chesa, Wolfgang J. Rettig, Klaus Damm, and Andreas Schnapp
Mechanism of Human Telomerase Inhibition by BIBR1532, a Synthetic, Non-nucleosidic Drug Candidate
J. Biol. Chem. 2002 277: 15566-15572. First Published on February 19, 2002; doi:10.1074/jbc.M201266200 [Abstract] [Full Text] [PDF]  

John A. Broadwater, Edward Whittle, and John Shanklin
Desaturation and Hydroxylation. RESIDUES 148 AND 324 OF ARABIDOPSIS FAD2, IN ADDITION TO SUBSTRATE CHAIN LENGTH, EXERT A MAJOR INFLUENCE IN PARTITIONING OF CATALYTIC SPECIFICITY
J. Biol. Chem. 2002 277: 15613-15620. First Published on February 25, 2002; doi:10.1074/jbc.M200231200 [Abstract] [Full Text] [PDF]  

Ting-Hui Lin, Hsing-Lin Lai, Yu-Ya Kao, Chung-Nan Sun, Ming-Jing Hwang, and Yijuang Chern
Protein Kinase C Inhibits Type VI Adenylyl Cyclase by Phosphorylating the Regulatory N Domain and Two Catalytic C1 and C2 Domains
J. Biol. Chem. 2002 277: 15721-15728. First Published on February 27, 2002; doi:10.1074/jbc.M111537200 [Abstract] [Full Text] [PDF]  

Frederic D. Sigoillot, David R. Evans, and Hedeel I. Guy
Growth-dependent Regulation of Mammalian Pyrimidine Biosynthesis by the Protein Kinase A and MAPK Signaling Cascades
J. Biol. Chem. 2002 277: 15745-15751. First Published on February 28, 2002; doi:10.1074/jbc.M201112200 [Abstract] [Full Text] [PDF]  

Qian Han, Jianmin Fang, and Jianyong Li
3-Hydroxykynurenine Transaminase Identity with Alanine Glyoxylate Transaminase. A PROBABLE DETOXIFICATION PROTEIN IN AEDES AEGYPTI
J. Biol. Chem. 2002 277: 15781-15787. First Published on March 5, 2002; doi:10.1074/jbc.M201202200 [Abstract] [Full Text] [PDF]  

Andrew C. Terentis, Shane R. Thomas, Osamu Takikawa, Tamantha K. Littlejohn, Roger J. W. Truscott, Robert S. Armstrong, Syun-Ru Yeh, and Roland Stocker
The Heme Environment of Recombinant Human Indoleamine 2,3-Dioxygenase. STRUCTURAL PROPERTIES AND SUBSTRATE-LIGAND INTERACTIONS
J. Biol. Chem. 2002 277: 15788-15794. First Published on February 26, 2002; doi:10.1074/jbc.M200457200 [Abstract] [Full Text] [PDF]  

Anne M. Gurnett, Paul A. Liberator, Paula M. Dulski, Scott P. Salowe, Robert G. K. Donald, Jennifer W. Anderson, Judyann Wiltsie, Carmen A. Diaz, Georgiana Harris, Ben Chang, Sandra J. Darkin-Rattray, Bakela Nare, Tami Crumley, Penny Sue Blum, Andrew S. Misura, Tamas Tamas, Mohinder K. Sardana, Jeffrey Yuan, Tesfaye Biftu, and Dennis M. Schmatz
Purification and Molecular Characterization of cGMP-dependent Protein Kinase from Apicomplexan Parasites. A NOVEL CHEMOTHERAPEUTIC TARGET
J. Biol. Chem. 2002 277: 15913-15922. First Published on February 7, 2002; doi:10.1074/jbc.M108393200 [Abstract] [Full Text] [PDF]  

Noelene S. Quinsey, James C. Whisstock, Bernard Le Bonniec, Virginie Louvain, Stephen P. Bottomley, and Robert N. Pike
Molecular Determinants of the Mechanism Underlying Acceleration of the Interaction between Antithrombin and Factor Xa by Heparin Pentasaccharide
J. Biol. Chem. 2002 277: 15971-15978. First Published on February 19, 2002; doi:10.1074/jbc.M108131200 [Abstract] [Full Text] [PDF]  

Gregory A. Bannikov, Tatiana V. Karelina, Ivan E. Collier, Barry L. Marmer, and Gregory I. Goldberg
Substrate Binding of Gelatinase B Induces Its Enzymatic Activity in the Presence of Intact Propeptide
J. Biol. Chem. 2002 277: 16022-16027. First Published on February 11, 2002; doi:10.1074/jbc.M110931200 [Abstract] [Full Text] [PDF]  

Jennifer Westling, Amanda J. Fosang, Karena Last, Vivian P. Thompson, Kathy N. Tomkinson, Tracy Hebert, Thomas McDonagh, Lisa A. Collins-Racie, Edward R. LaVallie, Elisabeth A. Morris, and John D. Sandy
ADAMTS4 Cleaves at the Aggrecanase Site (Glu373-Ala374) and Secondarily at the Matrix Metalloproteinase Site (Asn341-Phe342) in the Aggrecan Interglobular Domain
J. Biol. Chem. 2002 277: 16059-16066. First Published on February 19, 2002; doi:10.1074/jbc.M108607200 [Abstract] [Full Text] [PDF]  

Subrata Adak, Kulwant S. Aulak, and Dennis J. Stuehr
Direct Evidence for Nitric Oxide Production by a Nitric-oxide Synthase-like Protein from Bacillus subtilis
J. Biol. Chem. 2002 277: 16167-16171. First Published on February 20, 2002; doi:10.1074/jbc.M201136200 [Abstract] [Full Text] [PDF]  

Jason T. Huse, Kangning Liu, Donald S. Pijak, Dan Carlin, Virginia M.-Y. Lee, and Robert W. Doms
beta -Secretase Processing in the Trans-Golgi Network Preferentially Generates Truncated Amyloid Species That Accumulate in Alzheimer's Disease Brain
J. Biol. Chem. 2002 277: 16278-16284. First Published on February 14, 2002; doi:10.1074/jbc.M111141200 [Abstract] [Full Text] [PDF]  

John M. Lyle, Amy Clewell, Kathryn Richmond, Oliver C. Richards, Debra A. Hope, Steve C. Schultz, and Karla Kirkegaard
Similar Structural Basis for Membrane Localization and Protein Priming by an RNA-dependent RNA Polymerase
J. Biol. Chem. 2002 277: 16324-16331. First Published on February 27, 2002; doi:10.1074/jbc.M112429200 [Abstract] [Full Text] [PDF]  

Yeon Mi Kim, Jieun Yun, Chong-Kil Lee, Hwanghee Lee, Kyung Rak Min, and Youngsoo Kim
Oxyresveratrol and Hydroxystilbene Compounds. INHIBITORY EFFECT ON TYROSINASE AND MECHANISM OF ACTION
J. Biol. Chem. 2002 277: 16340-16344. First Published on February 25, 2002; doi:10.1074/jbc.M200678200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:Back

Ranjana Pathania, Naveen K. Navani, Govindan Rajamohan, and Kanak L. Dikshit
Mycobacterium tuberculosis Hemoglobin HbO Associates with Membranes and Stimulates Cellular Respiration of Recombinant Escherichia coli
J. Biol. Chem. 2002 277: 15293-15302. First Published on January 16, 2002; doi:10.1074/jbc.M111478200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

G. R. Scott Budinger, May Tso, David S. McClintock, David A. Dean, Jacob I. Sznajder, and Navdeep S. Chandel
Hyperoxia-induced Apoptosis Does Not Require Mitochondrial Reactive Oxygen Species and Is Regulated by Bcl-2 Proteins
J. Biol. Chem. 2002 277: 15654-15660. First Published on February 27, 2002; doi:10.1074/jbc.M109317200 [Abstract] [Full Text] [PDF]  

Vivian Y. Lee, David S. McClintock, Matthew T. Santore, G. R. Scott Budinger, and Navdeep S. Chandel
Hypoxia Sensitizes Cells to Nitric Oxide-induced Apoptosis
J. Biol. Chem. 2002 277: 16067-16074. First Published on February 22, 2002; doi:10.1074/jbc.M111177200 [Abstract] [Full Text] [PDF]  

Tina M. Iverson, César Luna-Chavez, Laura R. Croal, Gary Cecchini, and Douglas C. Rees
Crystallographic Studies of the Escherichia coli Quinol-Fumarate Reductase with Inhibitors Bound to the Quinol-binding Site
J. Biol. Chem. 2002 277: 16124-16130. First Published on February 15, 2002; doi:10.1074/jbc.M200815200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:Back

Hilke A. Nentwich, Zehra Mustafa, Marilyn S. Rugg, Brian D. Marsden, Martin R. Cordell, David J. Mahoney, Suzanne C. Jenkins, Barbara Dowling, Erik Fries, Caroline M. Milner, John Loughlin, and Anthony J. Day
A Novel Allelic Variant of the Human TSG-6 Gene Encoding an Amino Acid Difference in the CUB Module. CHROMOSOMAL LOCALIZATION, FREQUENCY ANALYSIS, MODELING, AND EXPRESSION
J. Biol. Chem. 2002 277: 15354-15362. First Published on February 19, 2002; doi:10.1074/jbc.M110765200 [Abstract] [Full Text] [PDF]  

Jae Kweon Park, Lai-Xi Wang, and Saul Roseman
Isolation of a Glucosamine-specific Kinase, a Unique Enzyme of Vibrio cholerae
J. Biol. Chem. 2002 277: 15573-15578. First Published on February 15, 2002; doi:10.1074/jbc.M107953200 [Abstract] [Full Text] [PDF]  

Kenneth K.-S. Ng, Anand R. Kolatkar, Shaun Park-Snyder, Hadar Feinberg, Damon A. Clark, Kurt Drickamer, and William I. Weis
Orientation of Bound Ligands in Mannose-binding Proteins. IMPLICATIONS FOR MULTIVALENT LIGAND RECOGNITION
J. Biol. Chem. 2002 277: 16088-16095. First Published on February 15, 2002; doi:10.1074/jbc.M200493200 [Abstract] [Full Text] [PDF]  

Ana M. Salicioni, Kellie S. Mizelle, Elena Loukinova, Irina Mikhailenko, Dudley K. Strickland, and Steven L. Gonias
The Low Density Lipoprotein Receptor-related Protein Mediates Fibronectin Catabolism and Inhibits Fibronectin Accumulation on Cell Surfaces
J. Biol. Chem. 2002 277: 16160-16166. First Published on February 26, 2002; doi:10.1074/jbc.M201401200 [Abstract] [Full Text] [PDF]  

Sayuri Hara-Kuge, Takashi Ohkura, Hiroko Ideo, Osamu Shimada, Saoko Atsumi, and Katsuko Yamashita
Involvement of VIP36 in Intracellular Transport and Secretion of Glycoproteins in Polarized Madin-Darby Canine Kidney (MDCK) Cells
J. Biol. Chem. 2002 277: 16332-16339. First Published on February 28, 2002; doi:10.1074/jbc.M112188200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:Back

Minna Kärkkäinen, Tomoichiro Oka, Vesa M. Olkkonen, Jari Metso, Hiroaki Hattori, Matti Jauhiainen, and Christian Ehnholm
Isolation and Partial Characterization of the Inactive and Active Forms of Human Plasma Phospholipid Transfer Protein (PLTP)
J. Biol. Chem. 2002 277: 15413-15418. First Published on February 19, 2002; doi:10.1074/jbc.M112247200 [Abstract] [Full Text] [PDF]  

Yong-Mei Zhang, Hedia Marrakchi, and Charles O. Rock
The FabR (YijC) Transcription Factor Regulates Unsaturated Fatty Acid Biosynthesis in Escherichia coli
J. Biol. Chem. 2002 277: 15558-15565. First Published on February 21, 2002; doi:10.1074/jbc.M201399200 [Abstract] [Full Text] [PDF]  

Hing C. Wong, Gaohua Liu, Yong-Mei Zhang, Charles O. Rock, and Jie Zheng
The Solution Structure of Acyl Carrier Protein from Mycobacterium tuberculosis
J. Biol. Chem. 2002 277: 15874-15880. First Published on February 1, 2002; doi:10.1074/jbc.M112300200 [Abstract] [Full Text] [PDF]  

Shaohua Tang, Bobby Bhatia, Carlos J. Maldonado, Peiying Yang, Robert A. Newman, Junwei Liu, Dhyan Chandra, Jeanine Traag, Russell D. Klein, Susan M. Fischer, Dharam Chopra, Jianjun Shen, Haiyen E. Zhau, Leland W. K. Chung, and Dean G. Tang
Evidence That Arachidonate 15-Lipoxygenase 2 Is a Negative Cell Cycle Regulator in Normal Prostate Epithelial Cells
J. Biol. Chem. 2002 277: 16189-16201. First Published on February 11, 2002; doi:10.1074/jbc.M111936200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Membrane Transport, Structure, Function, and Biogenesis:Back

Jian Song, Oran Kwon, Shenglin Chen, Rushad Daruwala, Peter Eck, Jae B. Park, and Mark Levine
Flavonoid Inhibition of Sodium-dependent Vitamin C Transporter 1 (SVCT1) and Glucose Transporter Isoform 2 (GLUT2), Intestinal Transporters for Vitamin C and Glucose
J. Biol. Chem. 2002 277: 15252-15260. First Published on February 7, 2002; doi:10.1074/jbc.M110496200 [Abstract] [Full Text] [PDF]  

Luba Aleksandrov, Andrei A. Aleksandrov, Xiu-bao Chang, and John R. Riordan
The First Nucleotide Binding Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is a Site of Stable Nucleotide Interaction, whereas the Second Is a Site of Rapid Turnover
J. Biol. Chem. 2002 277: 15419-15425. First Published on February 22, 2002; doi:10.1074/jbc.M111713200 [Abstract] [Full Text] [PDF]  

Kamran Salim, Tim Fenton, Jamil Bacha, Hector Urien-Rodriguez, Tim Bonnert, Heather A. Skynner, Emma Watts, Julie Kerby, Anne Heald, Margaret Beer, George McAllister, and Paul C. Guest
Oligomerization of G-protein-coupled Receptors Shown by Selective Co-immunoprecipitation
J. Biol. Chem. 2002 277: 15482-15485. First Published on February 19, 2002; doi:10.1074/jbc.M201539200 [Abstract] [Full Text] [PDF]  

Takashi Tsuboi, Susumu Terakawa, Bethe A. Scalettar, Claire Fantus, John Roder, and Andreas Jeromin
Sweeping Model of Dynamin Activity. VISUALIZATION OF COUPLING BETWEEN EXOCYTOSIS AND ENDOCYTOSIS UNDER AN EVANESCENT WAVE MICROSCOPE WITH GREEN FLUORESCENT PROTEINS
J. Biol. Chem. 2002 277: 15957-15961. First Published on February 20, 2002; doi:10.1074/jbc.C200051200 [Abstract] [Full Text] [PDF]  

Anne A. Wolf, Yukako Fujinaga, and Wayne I. Lencer
Uncoupling of the Cholera Toxin-GM1 Ganglioside Receptor Complex from Endocytosis, Retrograde Golgi Trafficking, and Downstream Signal Transduction by Depletion of Membrane Cholesterol
J. Biol. Chem. 2002 277: 16249-16256. First Published on February 21, 2002; doi:10.1074/jbc.M109834200 [Abstract] [Full Text] [PDF]  

Paul Cheresh, Travis Harrison, Hisashi Fujioka, and Kasturi Haldar
Targeting the Malarial Plastid via the Parasitophorous Vacuole
J. Biol. Chem. 2002 277: 16265-16277. First Published on January 28, 2002; doi:10.1074/jbc.M109331200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Mechanisms Of Signal Transduction:Back

Yutaka Umayahara, Yoshitaka Kajimoto, Yoshio Fujitani, Shin-ichi Gorogawa, Tetsuyuki Yasuda, Akio Kuroda, Kentaro Ohtoshi, Shigeru Yoshida, Dan Kawamori, Yoshimitsu Yamasaki, and Masatsugu Hori
Protein Kinase C-dependent, CCAAT/Enhancer-binding Protein beta -mediated Expression of Insulin-like Growth Factor I Gene
J. Biol. Chem. 2002 277: 15261-15270. First Published on February 1, 2002; doi:10.1074/jbc.M110827200 [Abstract] [Full Text] [PDF]  

Jürgen U. Linder, Anita Schultz, and Joachim E. Schultz
Adenylyl Cyclase Rv1264 from Mycobacterium tuberculosis Has an Autoinhibitory N-terminal Domain
J. Biol. Chem. 2002 277: 15271-15276. First Published on February 11, 2002; doi:10.1074/jbc.M200235200 [Abstract] [Full Text] [PDF]  

Simon J. Slater, Jodie L. Seiz, Anthony C. Cook, Christopher J. Buzas, Steve A. Malinowski, Jennifer L. Kershner, Brigid A. Stagliano, and Christopher D. Stubbs
Regulation of PKCalpha Activity by C1-C2 Domain Interactions
J. Biol. Chem. 2002 277: 15277-15285. First Published on February 15, 2002; doi:10.1074/jbc.M112207200 [Abstract] [Full Text] [PDF]  

Ginell R. Post, Carol Swiderski, Bruce A. Waldrop, Lina Salty, Christopher C. Glembotski, Rob M. F. Wolthuis, and Naoki Mochizuki
Guanine Nucleotide Exchange Factor-like Factor (Rlf) Induces Gene Expression and Potentiates alpha 1-Adrenergic Receptor-induced Transcriptional Responses in Neonatal Rat Ventricular Myocytes
J. Biol. Chem. 2002 277: 15286-15292. First Published on February 14, 2002; doi:10.1074/jbc.M111844200 [Abstract] [Full Text] [PDF]  

Xianwu Li, Li Liu, Joan C. Tupper, Douglas D. Bannerman, Robert K. Winn, Said M. Sebti, Andrew D. Hamilton, and John M. Harlan
Inhibition of Protein Geranylgeranylation and RhoA/RhoA Kinase Pathway Induces Apoptosis in Human Endothelial Cells
J. Biol. Chem. 2002 277: 15309-15316. First Published on February 11, 2002; doi:10.1074/jbc.M201253200 [Abstract] [Full Text] [PDF]  

Byung-Chun Yoo, Jung-Youn Lee, and William J. Lucas
Analysis of the Complexity of Protein Kinases within the Phloem Sieve Tube System. CHARACTERIZATION OF CUCURBITA MAXIMA CALMODULIN-LIKE DOMAIN PROTEIN KINASE 1
J. Biol. Chem. 2002 277: 15325-15332. First Published on February 14, 2002; doi:10.1074/jbc.M200382200 [Abstract] [Full Text] [PDF]  

Céline Charvet, Patrick Auberger, Sophie Tartare-Deckert, Alain Bernard, and Marcel Deckert
Vav1 Couples T Cell Receptor to Serum Response Factor-dependent Transcription via a MEK-dependent Pathway
J. Biol. Chem. 2002 277: 15376-15384. First Published on February 21, 2002; doi:10.1074/jbc.M111627200 [Abstract] [Full Text] [PDF]  

J. Kevin Leach, Stephen M. Black, Rupert K. Schmidt-Ullrich, and Ross B. Mikkelsen
Activation of Constitutive Nitric-oxide Synthase Activity Is an Early Signaling Event Induced by Ionizing Radiation
J. Biol. Chem. 2002 277: 15400-15406. First Published on February 20, 2002; doi:10.1074/jbc.M110309200 [Abstract] [Full Text] [PDF]  

Xin Wang, Yue Yang, Xiaojian Guo, Erik R. Sampson, Cheng-Lung Hsu, Meng-Yin Tsai, Shuyuan Yeh, Guan Wu, Yinglu Guo, and Chawnshang Chang
Suppression of Androgen Receptor Transactivation by Pyk2 via Interaction and Phosphorylation of the ARA55 Coregulator
J. Biol. Chem. 2002 277: 15426-15431. First Published on February 20, 2002; doi:10.1074/jbc.M111218200 [Abstract] [Full Text] [PDF]  

Jeremiah Stitham, Aleksandar Stojanovic, and John Hwa
Impaired Receptor Binding and Activation Associated with a Human Prostacyclin Receptor Polymorphism
J. Biol. Chem. 2002 277: 15439-15444. First Published on February 19, 2002; doi:10.1074/jbc.M201187200 [Abstract] [Full Text] [PDF]  

Carsten Scheller, Sieghart Sopper, Peifeng Chen, Egbert Flory, Eleni Koutsilieri, Tomas Racek, Stephan Ludwig, Volker ter Meulen, and Christian Jassoy
Caspase Inhibition Activates HIV in Latently Infected Cells. ROLE OF TUMOR NECROSIS FACTOR RECEPTOR 1 AND CD95
J. Biol. Chem. 2002 277: 15459-15464. First Published on February 19, 2002; doi:10.1074/jbc.M200763200 [Abstract] [Full Text] [PDF]  

Richard Little, Victoria Colombo, Andrew Leech, and Ray Dixon
Direct Interaction of the NifL Regulatory Protein with the GlnK Signal Transducer Enables the Azotobacter vinelandii NifL-NifA Regulatory System to Respond to Conditions Replete for Nitrogen
J. Biol. Chem. 2002 277: 15472-15481. First Published on February 20, 2002; doi:10.1074/jbc.M112262200 [Abstract] [Full Text] [PDF]  

Elena Loukinova, Sripriya Ranganathan, Sergey Kuznetsov, Natalia Gorlatova, Mary M. Migliorini, Dmitri Loukinov, Paula G. Ulery, Irina Mikhailenko, Daniel A. Lawrence, and Dudley K. Strickland
Platelet-derived Growth Factor (PDGF)-induced Tyrosine Phosphorylation of the Low Density Lipoprotein Receptor-related Protein (LRP). EVIDENCE FOR INTEGRATED CO-RECEPTOR FUNCTION BETWEEN LRP AND THE PDGF
J. Biol. Chem. 2002 277: 15499-15506. First Published on February 19, 2002; doi:10.1074/jbc.M200427200 [Abstract] [Full Text] [PDF]  

Philippe Boucher, Pingsheng Liu, Michael Gotthardt, Thomas Hiesberger, Richard G. W. Anderson, and Joachim Herz
Platelet-derived Growth Factor Mediates Tyrosine Phosphorylation of the Cytoplasmic Domain of the Low Density Lipoprotein Receptor-related Protein in Caveolae
J. Biol. Chem. 2002 277: 15507-15513. First Published on February 19, 2002; doi:10.1074/jbc.M200428200 [Abstract] [Full Text] [PDF]  

Chung-Fang Lai and Su-Li Cheng
Signal Transductions Induced by Bone Morphogenetic Protein-2 and Transforming Growth Factor-beta in Normal Human Osteoblastic Cells
J. Biol. Chem. 2002 277: 15514-15522. First Published on February 19, 2002; doi:10.1074/jbc.M200794200 [Abstract] [Full Text] [PDF]  

Jonathon M. Willets, R. A. John Challiss, and Stefan R. Nahorski
Endogenous G Protein-coupled Receptor Kinase 6 Regulates M3 Muscarinic Acetylcholine Receptor Phosphorylation and Desensitization in Human SH-SY5Y Neuroblastoma Cells
J. Biol. Chem. 2002 277: 15523-15529. First Published on February 20, 2002; doi:10.1074/jbc.M111217200 [Abstract] [Full Text] [PDF]  

Jeffrey A. Jones and Yusuf A. Hannun
Tight Binding Inhibition of Protein Phosphatase-1 by Phosphatidic Acid. SPECIFICITY OF INHIBITION BY THE PHOSPHOLIPID
J. Biol. Chem. 2002 277: 15530-15538. First Published on February 20, 2002; doi:10.1074/jbc.M111555200 [Abstract] [Full Text] [PDF]  

Meng-Ru Shen, Tzi-Peng Yang, and Ming-Jer Tang
A Novel Function of BCL-2 Overexpression in Regulatory Volume Decrease. ENHANCING SWELLING-ACTIVATED Ca2+ ENTRY AND Cl- CHANNEL ACTIVITY
J. Biol. Chem. 2002 277: 15592-15599. First Published on February 22, 2002; doi:10.1074/jbc.M111043200 [Abstract] [Full Text] [PDF]  

Lisa Héron-Milhavet and Derek LeRoith
Insulin-like Growth Factor I Induces MDM2-dependent Degradation of p53 via the p38 MAPK Pathway in Response to DNA Damage
J. Biol. Chem. 2002 277: 15600-15606. First Published on February 27, 2002; doi:10.1074/jbc.M111142200 [Abstract] [Full Text] [PDF]  

James R. Stone and Tucker Collins
Rapid Phosphorylation of Heterogeneous Nuclear Ribonucleoprotein C1/C2 in Response to Physiologic Levels of Hydrogen Peroxide in Human Endothelial Cells
J. Biol. Chem. 2002 277: 15621-15628. First Published on February 27, 2002; doi:10.1074/jbc.M112153200 [Abstract] [Full Text] [PDF]  

Junko Doi, Hiroshi Takemori, Xing-zi Lin, Nanao Horike, Yoshiko Katoh, and Mitsuhiro Okamoto
Salt-inducible Kinase Represses cAMP-dependent Protein Kinase-mediated Activation of Human Cholesterol Side Chain Cleavage Cytochrome P450 Promoter through the CREB Basic Leucine Zipper Domain
J. Biol. Chem. 2002 277: 15629-15637. First Published on February 25, 2002; doi:10.1074/jbc.M109365200 [Abstract] [Full Text] [PDF]  

Peter Macpherson, Tatiana Kostrominova, Huibin Tang, and Daniel Goldman
Protein Kinase C and Calcium/Calmodulin-activated Protein Kinase II (CaMK II) Suppress Nicotinic Acetylcholine Receptor Gene Expression in Mammalian Muscle. A SPECIFIC ROLE FOR CaMK II IN ACTIVITY-DEPENDENT GENE EXPRESSION
J. Biol. Chem. 2002 277: 15638-15646. First Published on February 27, 2002; doi:10.1074/jbc.M109864200 [Abstract] [Full Text] [PDF]  

Michael Potente, U. Ruth Michaelis, Beate Fisslthaler, Rudi Busse, and Ingrid Fleming
Cytochrome P450 2C9-induced Endothelial Cell Proliferation Involves Induction of Mitogen-activated Protein (MAP) Kinase Phosphatase-1, Inhibition of the c-Jun N-terminal Kinase, and Up-regulation of Cyclin D1
J. Biol. Chem. 2002 277: 15671-15676. First Published on February 26, 2002; doi:10.1074/jbc.M110806200 [Abstract] [Full Text] [PDF]  

Xinjiang Wang, Dan Michael, Gilbert de Murcia, and Moshe Oren
p53 Activation by Nitric Oxide Involves Down-regulation of Mdm2
J. Biol. Chem. 2002 277: 15697-15702. First Published on February 26, 2002; doi:10.1074/jbc.M112068200 [Abstract] [Full Text] [PDF]  

Yijiang Shi, Jung-hsin Hsu, Liping Hu, Joseph Gera, and Alan Lichtenstein
Signal Pathways Involved in Activation of p70S6K and Phosphorylation of 4E-BP1 following Exposure of Multiple Myeloma Tumor Cells to Interleukin-6
J. Biol. Chem. 2002 277: 15712-15720. First Published on February 28, 2002; doi:10.1074/jbc.M200043200 [Abstract] [Full Text] [PDF]  

Janet D. Lowe, Jeremy P. Celver, Vsevolod V. Gurevich, and Charles Chavkin
µ-Opioid Receptors Desensitize Less Rapidly than delta -Opioid Receptors Due to Less Efficient Activation of Arrestin
J. Biol. Chem. 2002 277: 15729-15735. First Published on February 22, 2002; doi:10.1074/jbc.M200612200 [Abstract] [Full Text] [PDF]  

Bing Hu, Carol Senkler, Alexander Yang, Florentina Soto, and Bruce T. Liang
P2X4 Receptor Is a Glycosylated Cardiac Receptor Mediating a Positive Inotropic Response to ATP
J. Biol. Chem. 2002 277: 15752-15757. First Published on February 25, 2002; doi:10.1074/jbc.M112097200 [Abstract] [Full Text] [PDF]  

Yuqi Wang and Henrik G. Dohlman
Pheromone-dependent Ubiquitination of the Mitogen-activated Protein Kinase Kinase Ste7
J. Biol. Chem. 2002 277: 15766-15772. First Published on February 25, 2002; doi:10.1074/jbc.M111733200 [Abstract] [Full Text] [PDF]  

ChangWoo Lee, Inhae Ji, KiSung Ryu, YongSang Song, P. Michael Conn, and Tae H. Ji
Two Defective Heterozygous Luteinizing Hormone Receptors Can Rescue Hormone Action
J. Biol. Chem. 2002 277: 15795-15800. First Published on February 21, 2002; doi:10.1074/jbc.M111818200 [Abstract] [Full Text] [PDF]  

Edwin C. Thrower, Hee Yun Park, Seung Ho So, Seung Hyun Yoo, and Barbara E. Ehrlich
Activation of the Inositol 1,4,5-Trisphosphate Receptor by the Calcium Storage Protein Chromogranin A
J. Biol. Chem. 2002 277: 15801-15806. First Published on February 12, 2002; doi:10.1074/jbc.M110139200 [Abstract] [Full Text] [PDF]  

Hiroshi Tokumitsu, Hiroyuki Inuzuka, Yumi Ishikawa, Masahiko Ikeda, Ikutaro Saji, and Ryoji Kobayashi
STO-609, a Specific Inhibitor of the Ca2+/Calmodulin-dependent Protein Kinase Kinase
J. Biol. Chem. 2002 277: 15813-15818. First Published on February 26, 2002; doi:10.1074/jbc.M201075200 [Abstract] [Full Text] [PDF]  

Atsushi Mizutani, Takako Furukawa, Yasushi Adachi, Susumu Ikehara, and Shigeru Taketani
A Zinc-finger Protein, PLAGL2, Induces the Expression of a Proapoptotic Protein Nip3, Leading to Cellular Apoptosis
J. Biol. Chem. 2002 277: 15851-15858. First Published on February 6, 2002; doi:10.1074/jbc.M111431200 [Abstract] [Full Text] [PDF]  

Joe B. Blumer, L. Judson Chandler, and Stephen M. Lanier
Expression Analysis and Subcellular Distribution of the Two G-protein Regulators AGS3 and LGN Indicate Distinct Functionality. LOCALIZATION OF LGN TO THE MIDBODY DURING CYTOKINESIS
J. Biol. Chem. 2002 277: 15897-15903. First Published on February 6, 2002; doi:10.1074/jbc.M112185200 [Abstract] [Full Text] [PDF]  

Monica Kong, Ching S. Wang, and Daniel J. Donoghue
Interaction of Fibroblast Growth Factor Receptor 3 and the Adapter Protein SH2-B. A ROLE IN STAT5 ACTIVATION
J. Biol. Chem. 2002 277: 15962-15970. First Published on February 4, 2002; doi:10.1074/jbc.M102777200 [Abstract] [Full Text] [PDF]  

Danying Chen, Xiaoyan Li, Zhonghe Zhai, and Hong-Bing Shu
A Novel Zinc Finger Protein Interacts with Receptor-interacting Protein (RIP) and Inhibits Tumor Necrosis Factor (TNF)- and IL1-induced NF-kappa B Activation
J. Biol. Chem. 2002 277: 15985-15991. First Published on February 19, 2002; doi:10.1074/jbc.M108675200 [Abstract] [Full Text] [PDF]  

Paula M. Bryan and Lincoln R. Potter
The Atrial Natriuretic Peptide Receptor (NPR-A/GC-A) Is Dephosphorylated by Distinct Microcystin-sensitive and Magnesium-dependent Protein Phosphatases
J. Biol. Chem. 2002 277: 16041-16047. First Published on January 30, 2002; doi:10.1074/jbc.M110626200 [Abstract] [Full Text] [PDF]  

Mariana S. Silveira, Mariana R. Costa, Marcelo Bozza, and Rafael Linden
Pituitary Adenylyl Cyclase-activating Polypeptide Prevents Induced Cell Death in Retinal Tissue through Activation of Cyclic AMP-dependent Protein Kinase
J. Biol. Chem. 2002 277: 16075-16080. First Published on February 14, 2002; doi:10.1074/jbc.M110106200 [Abstract] [Full Text] [PDF]  

Eric Camerer, Hiroshi Kataoka, Mark Kahn, Katy Lease, and Shaun R. Coughlin
Genetic Evidence That Protease-activated Receptors Mediate Factor Xa Signaling in Endothelial Cells
J. Biol. Chem. 2002 277: 16081-16087. First Published on February 15, 2002; doi:10.1074/jbc.M108555200 [Abstract] [Full Text] [PDF]  

Ted O'Neill, Lauren Giarratani, Ping Chen, Lakshmanan Iyer, Chang-Hun Lee, Matthew Bobiak, Fumihiko Kanai, Bin-Bing Zhou, Jay H. Chung, and Gary A. Rathbun
Determination of Substrate Motifs for Human Chk1 and hCds1/Chk2 by the Oriented Peptide Library Approach
J. Biol. Chem. 2002 277: 16102-16115. First Published on January 30, 2002; doi:10.1074/jbc.M111705200 [Abstract] [Full Text] [PDF]  

Robert Köchl, Martina Alken, Claudia Rutz, Gerd Krause, Alexander Oksche, Walter Rosenthal, and Ralf Schülein
The Signal Peptide of the G Protein-coupled Human Endothelin B Receptor Is Necessary for Translocation of the N-terminal Tail across the Endoplasmic Reticulum Membrane
J. Biol. Chem. 2002 277: 16131-16138. First Published on February 19, 2002; doi:10.1074/jbc.M111674200 [Abstract] [Full Text] [PDF]  

Alexander G. Obukhov and Martha C. Nowycky
TRPC4 Can Be Activated by G-protein-coupled Receptors and Provides Sufficient Ca2+ to Trigger Exocytosis in Neuroendocrine Cells
J. Biol. Chem. 2002 277: 16172-16178. First Published on February 20, 2002; doi:10.1074/jbc.M111664200 [Abstract] [Full Text] [PDF]  

Pamela M. Holland, Alison Milne, Kirsten Garka, Richard S. Johnson, Cynthia Willis, John E. Sims, Charles T. Rauch, Timothy A. Bird, and G. Duke Virca
Purification, Cloning, and Characterization of Nek8, a Novel NIMA-related Kinase, and Its Candidate Substrate Bicd2
J. Biol. Chem. 2002 277: 16229-16240. First Published on February 25, 2002; doi:10.1074/jbc.M108662200 [Abstract] [Full Text] [PDF]  

M. Fatima Leite, Keiji Hirata, Thomas Pusl, Angela D. Burgstahler, Keisuke Okazaki, J. Miguel Ortega, Alfredo M. Goes, Marco A. M. Prado, David C. Spray, and Michael H. Nathanson
Molecular Basis for Pacemaker Cells in Epithelia
J. Biol. Chem. 2002 277: 16313-16323. First Published on February 15, 2002; doi:10.1074/jbc.M109207200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:Back

Helen Petropoulos and Ilona S. Skerjanc
beta -Catenin Is Essential and Sufficient for Skeletal Myogenesis in P19 Cells
J. Biol. Chem. 2002 277: 15393-15399. First Published on February 20, 2002; doi:10.1074/jbc.M112141200 [Abstract] [Full Text] [PDF]  

Naveed Ahmed Khan, Ying Wang, Kee Jun Kim, Jin Woong Chung, Carol Ann Wass, and Kwang Sik Kim
Cytotoxic Necrotizing Factor-1 Contributes to Escherichia coli K1 Invasion of the Central Nervous System
J. Biol. Chem. 2002 277: 15607-15612. First Published on February 27, 2002; doi:10.1074/jbc.M112224200 [Abstract] [Full Text] [PDF]  

Morten O. Christensen, Hans U. Barthelmes, Silke Feineis, Birgitta R. Knudsen, Anni H. Andersen, Fritz Boege, and Christian Mielke
Changes in Mobility Account for Camptothecin-induced Subnuclear Relocation of Topoisomerase I
J. Biol. Chem. 2002 277: 15661-15665. First Published on March 20, 2002; doi:10.1074/jbc.C200066200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Pascal Kienlen-Campard, Sarah Miolet, Bernadette Tasiaux, and Jean-Noël Octave
Intracellular Amyloid-beta 1-42, but Not Extracellular Soluble Amyloid-beta Peptides, Induces Neuronal Apoptosis
J. Biol. Chem. 2002 277: 15666-15670. First Published on February 22, 2002; doi:10.1074/jbc.M200887200 [Abstract] [Full Text] [PDF]  

Fei Yu, Russell L. Finley, Jr., Avraham Raz, and Hyeong-Reh Choi Kim
Galectin-3 Translocates to the Perinuclear Membranes and Inhibits Cytochrome c Release from the Mitochondria. A ROLE FOR SYNEXIN IN GALECTIN-3 TRANSLOCATION
J. Biol. Chem. 2002 277: 15819-15827. First Published on February 11, 2002; doi:10.1074/jbc.M200154200 [Abstract] [Full Text] [PDF]  

Takumi Misaka, Tomoyuki Miyashita, and Yoshihiro Kubo
Primary Structure of a Dynamin-related Mouse Mitochondrial GTPase and Its Distribution in Brain, Subcellular Localization, and Effect on Mitochondrial Morphology
J. Biol. Chem. 2002 277: 15834-15842. First Published on February 14, 2002; doi:10.1074/jbc.M109260200 [Abstract] [Full Text] [PDF]  

Melissa H. Wong, Joerg Huelsken, Walter Birchmeier, and Jeffrey I. Gordon
Selection of Multipotent Stem Cells during Morphogenesis of Small Intestinal Crypts of Lieberkühn Is Perturbed by Stimulation of Lef-1/beta -Catenin Signaling
J. Biol. Chem. 2002 277: 15843-15850. First Published on February 19, 2002; doi:10.1074/jbc.M200184200 [Abstract] [Full Text] [PDF]  

Sunday Crider-Pirkle, Peggy Billingsley, Charles Faust, Daniel M. Hardy, Vaughan Lee, and Harry Weitlauf
Cubilin, a Binding Partner for Galectin-3 in the Murine Utero-Placental Complex
J. Biol. Chem. 2002 277: 15904-15912. First Published on February 20, 2002; doi:10.1074/jbc.M200331200 [Abstract] [Full Text] [PDF]  

Minna Eriksson and Sirpa Leppä
Mitogen-activated Protein Kinases and Activator Protein 1 Are Required for Proliferation and Cardiomyocyte Differentiation of P19 Embryonal Carcinoma Cells
J. Biol. Chem. 2002 277: 15992-16001. First Published on March 7, 2002; doi:10.1074/jbc.M107340200 [Abstract] [Full Text] [PDF]  

Mehboob A. Hussain, Christopher P. Miller, and Joel F. Habener
Brn-4 Transcription Factor Expression Targeted to the Early Developing Mouse Pancreas Induces Ectopic Glucagon Gene Expression in Insulin-producing beta Cells
J. Biol. Chem. 2002 277: 16028-16032. First Published on February 7, 2002; doi:10.1074/jbc.M107124200 [Abstract] [Full Text] [PDF]  

Denise M. Ferkey and David Kimelman
Glycogen Synthase Kinase-3beta Mutagenesis Identifies a Common Binding Domain for GBP and Axin
J. Biol. Chem. 2002 277: 16147-16152. First Published on February 22, 2002; doi:10.1074/jbc.M112363200 [Abstract] [Full Text] [PDF]  

Ines Nasdala, Karen Wolburg-Buchholz, Hartwig Wolburg, Annegret Kuhn, Klaus Ebnet, Gertrud Brachtendorf, Ulrike Samulowitz, Bernhard Kuster, Britta Engelhardt, Dietmar Vestweber, and Stefan Butz
A Transmembrane Tight Junction Protein Selectively Expressed on Endothelial Cells and Platelets
J. Biol. Chem. 2002 277: 16294-16303. First Published on February 14, 2002; doi:10.1074/jbc.M111999200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:Back

Minoru Fukuda, Nobuyoshi Hiraoka, Tomoya O. Akama, and Michiko N. Fukuda
Carbohydrate-modifying sulfotransferases. Structure, function, and pathophysiology.
J. Biol. Chem. 2002 277: 16345. [Full Text] [PDF]  

Mika Suzuki, Hiroshi Kobayashi, Michio Fujie, Takashi Nishida, Masaharu Takigawa, Naohiro Kanayama, and Toshihiko Terao
Kunitz-type protease inhibitor bikunin disrupts phorbol ester-induced oligomerization of CD44 variant isoforms containing epitope v9 and subsequently suppresses expression of urokinase-type plasminogen activator in human chondrosarcoma cells.
J. Biol. Chem. 2002 277: 16346. [Full Text] [PDF]  


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