JBC Focus on PI3-Kinase with Echelon

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Table of Contents: Jun 14 2002; 277 (24)   [Index by Author] 
[Cover Figure and Caption]
      Down Classics
      Down Accelerated Publications
      Down DNA: Replication, Repair, and Recombination
      Down Genes: Structure and Regulation
      Down RNA: Structure, Metabolism, and Catalysis
      Down Protein Synthesis, Post-Translation Modification, and Degradation
      Down Genomics, Proteomics, and Bioinformatics
      Down Protein Structure and Folding
      Down Enzyme Catalysis and Regulation
      Down Metabolism and Bioenergetics
      Down Glycobiology and Extracellular Matrices
      Down Lipids and Lipoproteins
      Down Membrane Transport, Structure, Function, and Biogenesis
      Down Mechanisms Of Signal Transduction
      Down Molecular Basis Of Cell and Developmental Biology
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Classics:Back

Robert D. Simoni, Robert L. Hill, and Martha Vaughan
The Discovery of Glutathione by F. Gowland Hopkins and the Beginning of Biochemistry at Cambridge University
ON GLUTATHIONE. II. A THERMOSTABLE OXIDATION-REDUCTION SYSTEM (F. Gowland Hopkins and M. Dixon J. Biol. Chem. 54, 527-563)
J. Biol. Chem. 2002 277: e13. [Full Text]  


Accelerated Publications:Back

Jonathan E. Moody, Linda Millen, Derk Binns, John F. Hunt, and Philip J. Thomas
Cooperative, ATP-dependent Association of the Nucleotide Binding Cassettes during the Catalytic Cycle of ATP-binding Cassette Transporters
J. Biol. Chem. 2002 277: 21111-21114. First Published on April 18, 2002; doi:10.1074/jbc.C200228200 [Abstract] [Full Text] [PDF]  

Kozo Hamada, Tomoko Miyata, Kouta Mayanagi, Junji Hirota, and Katsuhiko Mikoshiba
Two-state Conformational Changes in Inositol 1,4,5-Trisphosphate Receptor Regulated by Calcium
J. Biol. Chem. 2002 277: 21115-21118. First Published on April 29, 2002; doi:10.1074/jbc.C200244200 [Abstract] [Full Text] [PDF]  

Srinivasa M. Srinivasula, Jean-Luc Poyet, Marjaneh Razmara, Pinaki Datta, ZhiJia Zhang, and Emad S. Alnemri
The PYRIN-CARD Protein ASC Is an Activating Adaptor for Caspase-1
J. Biol. Chem. 2002 277: 21119-21122. First Published on April 19, 2002; doi:10.1074/jbc.C200179200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:Back

Helen Budworth, Irina I. Dianova, Vladimir N. Podust, and Grigory L. Dianov
Repair of Clustered DNA Lesions. SEQUENCE-SPECIFIC INHIBITION OF LONG-PATCH BASE EXCISION REPAIR BY 8-OXOGUANINE
J. Biol. Chem. 2002 277: 21300-21305. First Published on March 28, 2002; doi:10.1074/jbc.M201918200 [Abstract] [Full Text] [PDF]  

Yoko Fujioka, Yukio Kimata, Koji Nomaguchi, Kenji Watanabe, and Kenji Kohno
Identification of a Novel Non-structural Maintenance of Chromosomes (SMC) Component of the SMC5-SMC6 Complex Involved in DNA Repair
J. Biol. Chem. 2002 277: 21585-21591. First Published on April 1, 2002; doi:10.1074/jbc.M201523200 [Abstract] [Full Text] [PDF]  

Piotr Widlak, Olena Palyvoda, Slawomir Kumala, and William T. Garrard
Modeling Apoptotic Chromatin Condensation in Normal Cell Nuclei. REQUIREMENT FOR INTRANUCLEAR MOBILITY AND ACTIN INVOLVEMENT
J. Biol. Chem. 2002 277: 21683-21690. First Published on April 1, 2002; doi:10.1074/jbc.M201027200 [Abstract] [Full Text] [PDF]  

Guy Tomer, Andrew B. Buermeyer, Megan M. Nguyen, and R. Michael Liskay
Contribution of Human Mlh1 and Pms2 ATPase Activities to DNA Mismatch Repair
J. Biol. Chem. 2002 277: 21801-21809. First Published on March 15, 2002; doi:10.1074/jbc.M111342200 [Abstract] [Full Text] [PDF]  

Markus Räschle, Patrick Dufner, Giancarlo Marra, and Josef Jiricny
Mutations within the hMLH1 and hPMS2 Subunits of the Human MutLalpha Mismatch Repair Factor Affect Its ATPase Activity, but Not Its Ability to Interact with hMutSalpha
J. Biol. Chem. 2002 277: 21810-21820. First Published on April 10, 2002; doi:10.1074/jbc.M108787200 [Abstract] [Full Text] [PDF]  

Cayetano von Kobbe, Parimal Karmakar, Lale Dawut, Patricia Opresko, Xianmin Zeng, Robert M. Brosh, Jr., Ian D. Hickson, and Vilhelm A. Bohr
Colocalization, Physical, and Functional Interaction between Werner and Bloom Syndrome Proteins
J. Biol. Chem. 2002 277: 22035-22044. First Published on March 27, 2002; doi:10.1074/jbc.M200914200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:Back

Hazel Jardine, William MacNee, Kenneth Donaldson, and Irfan Rahman
Molecular Mechanism of Transforming Growth Factor (TGF)-beta 1-induced Glutathione Depletion in Alveolar Epithelial Cells. INVOLVEMENT OF AP-1/ARE AND Fra-1
J. Biol. Chem. 2002 277: 21158-21166. First Published on March 23, 2002; doi:10.1074/jbc.M112145200 [Abstract] [Full Text] [PDF]  

Bettina Tudzynski, María Cecilia Rojas, Paul Gaskin, and Peter Hedden
The Gibberellin 20-Oxidase of Gibberella fujikuroi Is a Multifunctional Monooxygenase
J. Biol. Chem. 2002 277: 21246-21253. First Published on April 9, 2002; doi:10.1074/jbc.M201651200 [Abstract] [Full Text] [PDF]  

Bassel Akache and Bernard Turcotte
New Regulators of Drug Sensitivity in the Family of Yeast Zinc Cluster Proteins
J. Biol. Chem. 2002 277: 21254-21260. First Published on April 9, 2002; doi:10.1074/jbc.M202566200 [Abstract] [Full Text] [PDF]  

Colin Conway, Richard McCulloch, Michael L. Ginger, Nicholas P. Robinson, Alison Browitt, and J. David Barry
Ku Is Important for Telomere Maintenance, but Not for Differential Expression of Telomeric VSG Genes, in African Trypanosomes
J. Biol. Chem. 2002 277: 21269-21277. First Published on March 27, 2002; doi:10.1074/jbc.M200550200 [Abstract] [Full Text] [PDF]  

Takanori Sakaguchi, Xiubin Gu, Heidi M. Golden, EunRan Suh, David B. Rhoads, and Hans-Christian Reinecker
Cloning of the Human Claudin-2 5'-Flanking Region Revealed a TATA-less Promoter with Conserved Binding Sites in Mouse and Human for Caudal-related Homeodomain Proteins and Hepatocyte Nuclear Factor-1alpha
J. Biol. Chem. 2002 277: 21361-21370. First Published on April 4, 2002; doi:10.1074/jbc.M110261200 [Abstract] [Full Text] [PDF]  

Oliver Valerius, Cornelia Brendel, Katrin Düvel, and Gerhard H. Braus
Multiple Factors Prevent Transcriptional Interference at the Yeast ARO4-HIS7 Locus
J. Biol. Chem. 2002 277: 21440-21445. First Published on April 5, 2002; doi:10.1074/jbc.M201841200 [Abstract] [Full Text] [PDF]  

Nicolas Bouché, Ariel Scharlat, Wayne Snedden, David Bouchez, and Hillel Fromm
A Novel Family of Calmodulin-binding Transcription Activators in Multicellular Organisms
J. Biol. Chem. 2002 277: 21851-21861. First Published on March 29, 2002; doi:10.1074/jbc.M200268200 [Abstract] [Full Text] [PDF]  

Anette Wärnmark, Eckardt Treuter, Jan-Åke Gustafsson, Roderick E. Hubbard, Andrzej M. Brzozowski, and Ashley C. W. Pike
Interaction of Transcriptional Intermediary Factor 2 Nuclear Receptor Box Peptides with the Coactivator Binding Site of Estrogen Receptor alpha
J. Biol. Chem. 2002 277: 21862-21868. First Published on April 5, 2002; doi:10.1074/jbc.M200764200 [Abstract] [Full Text] [PDF]  

Claudie Lemercier, Marie-Paule Brocard, Francine Puvion-Dutilleul, Hung-Ying Kao, Olivier Albagli, and Saadi Khochbin
Class II Histone Deacetylases Are Directly Recruited by BCL6 Transcriptional Repressor
J. Biol. Chem. 2002 277: 22045-22052. First Published on April 19, 2002; doi:10.1074/jbc.M201736200 [Abstract] [Full Text] [PDF]  


RNA: Structure, Metabolism, and Catalysis:Back

Priyanka D. Abeyrathne, Atanas I. Lalev, and Ross N. Nazar
A RAC Protein-binding Site in the Internal Transcribed Spacer 2 of Pre-rRNA Transcripts from Schizosaccharomyces pombe
J. Biol. Chem. 2002 277: 21291-21299. First Published on March 28, 2002; doi:10.1074/jbc.M201751200 [Abstract] [Full Text] [PDF]  

Anil K. Nair, John C. Kash, Helle Peegel, and K. M. J. Menon
Post-transcriptional Regulation of Luteinizing Hormone Receptor mRNA in the Ovary by a Novel mRNA-binding Protein
J. Biol. Chem. 2002 277: 21468-21473. First Published on April 8, 2002; doi:10.1074/jbc.M111653200 [Abstract] [Full Text] [PDF]  

Zhuan-Fen Cheng and Murray P. Deutscher
Purification and Characterization of the Escherichia coli Exoribonuclease RNase R. COMPARISON WITH RNase II
J. Biol. Chem. 2002 277: 21624-21629. First Published on April 10, 2002; doi:10.1074/jbc.M202942200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:Back

Philip Eaton, William Fuller, and Michael J. Shattock
S-Thiolation of HSP27 Regulates Its Multimeric Aggregate Size Independently of Phosphorylation
J. Biol. Chem. 2002 277: 21189-21196. First Published on March 29, 2002; doi:10.1074/jbc.M200591200 [Abstract] [Full Text] [PDF]  

Mingyu Zhang, Eric P. Smith, Hiroaki Kuroda, Walter Banach, Steven D. Chernausek, and James A. Fagin
Targeted Expression of a Protease-resistant IGFBP-4 Mutant in Smooth Muscle of Transgenic Mice Results in IGFBP-4 Stabilization and Smooth Muscle Hypotrophy
J. Biol. Chem. 2002 277: 21285-21290. First Published on March 28, 2002; doi:10.1074/jbc.M112082200 [Abstract] [Full Text] [PDF]  

Donghai Lin, Michael H. Tatham, Bin Yu, Suhkmann Kim, Ronald T. Hay, and Yuan Chen
Identification of a Substrate Recognition Site on Ubc9
J. Biol. Chem. 2002 277: 21740-21748. First Published on March 4, 2002; doi:10.1074/jbc.M108418200 [Abstract] [Full Text] [PDF]  

Angus Chen, Frida E. Kleiman, James L. Manley, Toru Ouchi, and Zhen-Qiang Pan
Autoubiquitination of the BRCA1·BARD1 RING Ubiquitin Ligase
J. Biol. Chem. 2002 277: 22085-22092. First Published on April 1, 2002; doi:10.1074/jbc.M201252200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:Back

Simona Panni, Luciana Dente, and Gianni Cesareni
In Vitro Evolution of Recognition Specificity Mediated by SH3 Domains Reveals Target Recognition Rules
J. Biol. Chem. 2002 277: 21666-21674. First Published on April 19, 2002; doi:10.1074/jbc.M109788200 [Abstract] [Full Text] [PDF]  

David Cappellen, Ngoc-Hong Luong-Nguyen, Sandrine Bongiovanni, Olivier Grenet, Christoph Wanke, and Mira Susa
Transcriptional Program of Mouse Osteoclast Differentiation Governed by the Macrophage Colony-stimulating Factor and the Ligand for the Receptor Activator of NFkappa B
J. Biol. Chem. 2002 277: 21971-21982. First Published on March 28, 2002; doi:10.1074/jbc.M200434200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:Back

Ilia V. Baskakov, Giuseppe Legname, Michael A. Baldwin, Stanley B. Prusiner, and Fred E. Cohen
Pathway Complexity of Prion Protein Assembly into Amyloid
J. Biol. Chem. 2002 277: 21140-21148. First Published on March 23, 2002; doi:10.1074/jbc.M111402200 [Abstract] [Full Text] [PDF]  

James L. McManaman and David L. Bain
Structural and Conformational Analysis of the Oxidase to Dehydrogenase Conversion of Xanthine Oxidoreductase
J. Biol. Chem. 2002 277: 21261-21268. First Published on March 25, 2002; doi:10.1074/jbc.M200828200 [Abstract] [Full Text] [PDF]  

Ben J. Mans, Abraham I. Louw, and Albert W. H. Neitz
Savignygrin, a Platelet Aggregation Inhibitor from the Soft Tick Ornithodoros savignyi, Presents the RGD Integrin Recognition Motif on the Kunitz-BPTI Fold
J. Biol. Chem. 2002 277: 21371-21378. First Published on April 3, 2002; doi:10.1074/jbc.M112060200 [Abstract] [Full Text] [PDF]  

Sheref S. Mansy, Gong Wu, Kristene K. Surerus, and J. A. Cowan
Iron-Sulfur Cluster Biosynthesis. THERMATOGA MARITIMA IscU IS A STRUCTURED IRON-SULFUR CLUSTER ASSEMBLY PROTEIN
J. Biol. Chem. 2002 277: 21397-21404. First Published on April 4, 2002; doi:10.1074/jbc.M201439200 [Abstract] [Full Text] [PDF]  

J. Glen Newell and Susan M. J. Dunn
Functional Consequences of the Loss of High Affinity Agonist Binding to gamma -Aminobutyric Acid Type A Receptors. IMPLICATIONS FOR RECEPTOR DESENSITIZATION
J. Biol. Chem. 2002 277: 21423-21430. First Published on April 3, 2002; doi:10.1074/jbc.M110312200 [Abstract] [Full Text] [PDF]  

Dong-Pyo Hong, Masayo Gozu, Kazuhiro Hasegawa, Hironobu Naiki, and Yuji Goto
Conformation of beta 2-Microglobulin Amyloid Fibrils Analyzed by Reduction of the Disulfide Bond
J. Biol. Chem. 2002 277: 21554-21560. First Published on April 9, 2002; doi:10.1074/jbc.M200188200 [Abstract] [Full Text] [PDF]  

Philip S. Renshaw, Parthena Panagiotidou, Adam Whelan, Stephen V. Gordon, R. Glyn Hewinson, Richard A. Williamson, and Mark D. Carr
Conclusive Evidence That the Major T-cell Antigens of the Mycobacterium tuberculosis Complex ESAT-6 and CFP-10 Form a Tight, 1:1 Complex and Characterization of the Structural Properties of ESAT-6, CFP-10, and the ESAT-6·CFP-10 Complex. IMPLICATIONS FOR PATHOGENESIS AND VIRULENCE
J. Biol. Chem. 2002 277: 21598-21603. First Published on April 8, 2002; doi:10.1074/jbc.M201625200 [Abstract] [Full Text] [PDF]  

José Solbiati, Anne Chapman-Smith, and John E. Cronan, Jr.
Stabilization of the Biotinoyl Domain of Escherichia coli Acetyl-CoA Carboxylase by Interactions between the Attached Biotin and the Protruding "Thumb" Structure
J. Biol. Chem. 2002 277: 21604-21609. First Published on April 9, 2002; doi:10.1074/jbc.M201928200 [Abstract] [Full Text] [PDF]  

Ji Young Choi, Sang Hyoung Lee, Chan Young Park, Won Do Heo, Jong Cheol Kim, Min Chul Kim, Woo Sik Chung, Byeong Cheol Moon, Yong Hwa Cheong, Cha Young Kim, Jae Hyuk Yoo, Ja Choon Koo, Hyun Mi Ok, Seung-Wook Chi, Seong-Eon Ryu, Sang Yeol Lee, Chae Oh Lim, and Moo Je Cho
Identification of Calmodulin Isoform-specific Binding Peptides from a Phage-displayed Random 22-mer Peptide Library
J. Biol. Chem. 2002 277: 21630-21638. First Published on March 18, 2002; doi:10.1074/jbc.M110803200 [Abstract] [Full Text] [PDF]  

Soojin Lee, Chun Yang Fan, J. Michael Younger, Hongyu Ren, and Douglas M. Cyr
Identification of Essential Residues in the Type II Hsp40 Sis1 That Function in Polypeptide Binding
J. Biol. Chem. 2002 277: 21675-21682. First Published on March 27, 2002; doi:10.1074/jbc.M111075200 [Abstract] [Full Text] [PDF]  

Christoph Eicken, Vivek Sharma, Thomas Klabunde, Matthew B. Lawrenz, John M. Hardham, Steven J. Norris, and James C. Sacchettini
Crystal Structure of Lyme Disease Variable Surface Antigen VlsE of Borrelia burgdorferi
J. Biol. Chem. 2002 277: 21691-21696. First Published on March 28, 2002; doi:10.1074/jbc.M201547200 [Abstract] [Full Text] [PDF]  

Indra Adi Lim, Duane D. Hall, and Johannes W. Hell
Selectivity and Promiscuity of the First and Second PDZ Domains of PSD-95 and Synapse-associated Protein 102
J. Biol. Chem. 2002 277: 21697-21711. First Published on April 5, 2002; doi:10.1074/jbc.M112339200 [Abstract] [Full Text] [PDF]  

Henrik J. Ditzel, Merel C. M. Strik, Morten K. Larsen, Antony C. Willis, Ahmad Waseem, Karin Kejling, and Jens C. Jensenius
Cancer-associated Cleavage of Cytokeratin 8/18 Heterotypic Complexes Exposes a Neoepitope in Human Adenocarcinomas
J. Biol. Chem. 2002 277: 21712-21722. First Published on March 28, 2002; doi:10.1074/jbc.M202140200 [Abstract] [Full Text] [PDF]  

Jun Funahashi, Kazufumi Takano, Yuriko Yamagata, and Katsuhide Yutani
Positive Contribution of Hydration Structure on the Surface of Human Lysozyme to the Conformational Stability
J. Biol. Chem. 2002 277: 21792-21800. First Published on April 1, 2002; doi:10.1074/jbc.M110728200 [Abstract] [Full Text] [PDF]  

Hee-Seob Lee, Min-Sung Kim, Hyun-Soo Cho, Jung-In Kim, Tae-Jip Kim, Ji-Hye Choi, Cheonseok Park, Heung-Soo Lee, Byung-Ha Oh, and Kwan-Hwa Park
Cyclomaltodextrinase, Neopullulanase, and Maltogenic Amylase Are Nearly Indistinguishable from Each Other
J. Biol. Chem. 2002 277: 21891-21897. First Published on March 28, 2002; doi:10.1074/jbc.M201623200 [Abstract] [Full Text] [PDF]  

Megumi Mito, Khoon Tee Chong, Gentaro Miyazaki, Shin-ichi Adachi, Sam-Yong Park, Jeremy R. H. Tame, and Hideki Morimoto
Crystal Structures of Deoxy- and Carbonmonoxyhemoglobin F1 from the Hagfish Eptatretus burgeri
J. Biol. Chem. 2002 277: 21898-21905. First Published on March 28, 2002; doi:10.1074/jbc.M111492200 [Abstract] [Full Text] [PDF]  

Yaqiong Lin, William C. Hwang, and Ravi Basavappa
Structural and Functional Analysis of the Human Mitotic-specific Ubiquitin-conjugating Enzyme, UbcH10
J. Biol. Chem. 2002 277: 21913-21921. First Published on April 1, 2002; doi:10.1074/jbc.M109398200 [Abstract] [Full Text] [PDF]  

Gergely Katona, Rupert C. Wilmouth, Penny A. Wright, Gunnar I. Berglund, Janos Hajdu, Richard Neutze, and Christopher J. Schofield
X-ray Structure of a Serine Protease Acyl-Enzyme Complex at 0.95-Å Resolution
J. Biol. Chem. 2002 277: 21962-21970. First Published on March 14, 2002; doi:10.1074/jbc.M200676200 [Abstract] [Full Text] [PDF]  

Lorella Franzoni, Christian Lücke, Carlos Pérez, Davide Cavazzini, Martin Rademacher, Christian Ludwig, Alberto Spisni, Gian Luigi Rossi, and Heinz Rüterjans
Structure and Backbone Dynamics of Apo- and Holo-cellular Retinol-binding Protein in Solution
J. Biol. Chem. 2002 277: 21983-21997. First Published on April 4, 2002; doi:10.1074/jbc.M201994200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:Back

Stéphane Hausmann and Stewart Shuman
Characterization of the CTD Phosphatase Fcp1 from Fission Yeast. PREFERENTIAL DEPHOSPHORYLATION OF SERINE 2 VERSUS SERINE 5
J. Biol. Chem. 2002 277: 21213-21220. First Published on April 4, 2002; doi:10.1074/jbc.M202056200 [Abstract] [Full Text] [PDF]  

Karim El Kirat, Françoise Besson, Annie-France Prigent, Jean-Paul Chauvet, and Bernard Roux
Role of Calcium and Membrane Organization on Phospholipase D Localization and Activity. COMPETITION BETWEEN A SOLUBLE AND AN INSOLUBLE SUBSTRATE
J. Biol. Chem. 2002 277: 21231-21236. First Published on April 8, 2002; doi:10.1074/jbc.M106449200 [Abstract] [Full Text] [PDF]  

Gideon Oudgenoeg, Eef Dirksen, Steen Ingemann, Riet Hilhorst, Harry Gruppen, Carmen G. Boeriu, Sander R. Piersma, Willem J. H. van Berkel, Colja Laane, and Alphons G. J. Voragen
Horseradish Peroxidase-catalyzed Oligomerization of Ferulic Acid on a Template of a Tyrosine-containing Tripeptide
J. Biol. Chem. 2002 277: 21332-21340. First Published on March 29, 2002; doi:10.1074/jbc.M201679200 [Abstract] [Full Text] [PDF]  

Zoltán Kukor, Julia Mayerle, Burkhard Krüger, Miklós Tóth, Paul M. Steed, Walter Halangk, Markus M. Lerch, and Miklós Sahin-Tóth
Presence of Cathepsin B in the Human Pancreatic Secretory Pathway and Its Role in Trypsinogen Activation during Hereditary Pancreatitis
J. Biol. Chem. 2002 277: 21389-21396. First Published on April 3, 2002; doi:10.1074/jbc.M200878200 [Abstract] [Full Text] [PDF]  

Matthew Daugherty, Boris Polanuyer, Michael Farrell, Michael Scholle, Athanasios Lykidis, Valérie de Crécy-Lagard, and Andrei Osterman
Complete Reconstitution of the Human Coenzyme A Biosynthetic Pathway via Comparative Genomics
J. Biol. Chem. 2002 277: 21431-21439. First Published on March 28, 2002; doi:10.1074/jbc.M201708200 [Abstract] [Full Text] [PDF]  

Mohammed El Mezgueldi, Nanyun Tang, Steven S. Rosenfeld, and E. Michael Ostap
The Kinetic Mechanism of Myo1e (Human Myosin-IC)
J. Biol. Chem. 2002 277: 21514-21521. First Published on April 8, 2002; doi:10.1074/jbc.M200713200 [Abstract] [Full Text] [PDF]  

Robert S. Phillips, Tatyana V. Demidkina, Lyudmila N. Zakomirdina, Stefano Bruno, Luca Ronda, and Andrea Mozzarelli
Crystals of Tryptophan Indole-Lyase and Tyrosine Phenol-Lyase Form Stable Quinonoid Complexes
J. Biol. Chem. 2002 277: 21592-21597. First Published on April 4, 2002; doi:10.1074/jbc.M200216200 [Abstract] [Full Text] [PDF]  

Catherine Gaille, Peter Kast, and Dieter Haas
Salicylate Biosynthesis in Pseudomonas aeruginosa. PURIFICATION AND CHARACTERIZATION OF PchB, A NOVEL BIFUNCTIONAL ENZYME DISPLAYING ISOCHORISMATE PYRUVATE-LYASE AND CHORISMATE MUTASE ACTIVITIES
J. Biol. Chem. 2002 277: 21768-21775. First Published on April 5, 2002; doi:10.1074/jbc.M202410200 [Abstract] [Full Text] [PDF]  

Stanislav Kopriva, Thomas Büchert, Günter Fritz, Marianne Suter, Rüdiger Benda, Volker Schünemann, Anna Koprivova, Peter Schürmann, Alfred X. Trautwein, Peter M. H. Kroneck, and Christian Brunold
The Presence of an Iron-Sulfur Cluster in Adenosine 5'-Phosphosulfate Reductase Separates Organisms Utilizing Adenosine 5'-Phosphosulfate and Phosphoadenosine 5'-Phosphosulfate for Sulfate Assimilation
J. Biol. Chem. 2002 277: 21786-21791. First Published on April 8, 2002; doi:10.1074/jbc.M202152200 [Abstract] [Full Text] [PDF]  

Lars C. Pedersen, Thomas A. Darden, and Masahiko Negishi
Crystal Structure of beta 1,3-Glucuronyltransferase I in Complex with Active Donor Substrate UDP-GlcUA
J. Biol. Chem. 2002 277: 21869-21873. First Published on April 11, 2002; doi:10.1074/jbc.M112343200 [Abstract] [Full Text] [PDF]  

Robert A. Maxwell, William H. Welch, and David A. Schooley
Juvenile Hormone Diol Kinase. I. PURIFICATION, CHARACTERIZATION, AND SUBSTRATE SPECIFICITY OF JUVENILE HORMONE-SELECTIVE DIOL KINASE FROM MANDUCA SEXTA
J. Biol. Chem. 2002 277: 21874-21881. First Published on March 21, 2002; doi:10.1074/jbc.M201510200 [Abstract] [Full Text] [PDF]  

Robert A. Maxwell, William H. Welch, Frank M. Horodyski, Kathleen M. Schegg, and David A. Schooley
Juvenile Hormone Diol Kinase. II. SEQUENCING, CLONING, AND MOLECULAR MODELING OF JUVENILE HORMONE-SELECTIVE DIOL KINASE FROM MANDUCA SEXTA
J. Biol. Chem. 2002 277: 21882-21890. First Published on March 21, 2002; doi:10.1074/jbc.M201509200 [Abstract] [Full Text] [PDF]  

Huma Khan, Richard J. Harris, Terez Barna, Daniel H. Craig, Neil. C. Bruce, Andrew W. Munro, Peter C. E. Moody, and Nigel S. Scrutton
Kinetic and Structural Basis of Reactivity of Pentaerythritol Tetranitrate Reductase with NADPH, 2-Cyclohexenone, Nitroesters, and Nitroaromatic Explosives
J. Biol. Chem. 2002 277: 21906-21912. First Published on March 28, 2002; doi:10.1074/jbc.M200637200 [Abstract] [Full Text] [PDF]  

David R. Hall, Charles S. Bond, Gordon A. Leonard, C. Ian Watt, Alan Berry, and William N. Hunter
Structure of Tagatose-1,6-bisphosphate Aldolase. INSIGHT INTO CHIRAL DISCRIMINATION, MECHANISM, AND SPECIFICITY OF CLASS II ALDOLASES
J. Biol. Chem. 2002 277: 22018-22024. First Published on April 8, 2002; doi:10.1074/jbc.M202464200 [Abstract] [Full Text] [PDF]  

Takayuki Nakayama, Tadashi Matsushita, Zhengyu Dong, J. Evan Sadler, Sylvie Jorieux, Claudine Mazurier, Dominique Meyer, Tetsuhito Kojima, and Hidehiko Saito
Identification of the Regulatory Elements of the Human von Willebrand Factor for Binding to Platelet GPIb. IMPORTANCE OF STRUCTURAL INTEGRITY OF THE REGIONS FLANKED BY THE CYS1272-CYS1458 DISULFIDE BOND
J. Biol. Chem. 2002 277: 22063-22072. First Published on April 9, 2002; doi:10.1074/jbc.M201327200 [Abstract] [Full Text] [PDF]  

Toshiyuki Nakanishi and Kazuhisa Sekimizu
SDT1/SSM1, a Multicopy Suppressor of S-II Null Mutant, Encodes a Novel Pyrimidine 5'-Nucleotidase
J. Biol. Chem. 2002 277: 22103-22106. First Published on April 4, 2002; doi:10.1074/jbc.M200573200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:Back

Nagendra Yadava, Prasanth Potluri, Erin N. Smith, Amina Bisevac, and Immo E. Scheffler
Species-specific and Mutant MWFE Proteins. THEIR EFFECT ON THE ASSEMBLY OF A FUNCTIONAL MAMMALIAN MITOCHONDRIAL COMPLEX I
J. Biol. Chem. 2002 277: 21221-21230. First Published on April 5, 2002; doi:10.1074/jbc.M202016200 [Abstract] [Full Text] [PDF]  

Tomoko Masaike, Eiro Muneyuki, Hiroyuki Noji, Kazuhiko Kinosita, Jr., and Masasuke Yoshida
F1-ATPase Changes Its Conformations upon Phosphate Release
J. Biol. Chem. 2002 277: 21643-21649. First Published on March 5, 2002; doi:10.1074/jbc.M110297200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:Back

Oren Dwir, Douglas A. Steeber, Ulrich S. Schwarz, Raymond T. Camphausen, Geoffrey S. Kansas, Thomas F. Tedder, and Ronen Alon
L-selectin Dimerization Enhances Tether Formation to Properly Spaced Ligand
J. Biol. Chem. 2002 277: 21130-21139. First Published on March 20, 2002; doi:10.1074/jbc.M201999200 [Abstract] [Full Text] [PDF]  

Iain B. H. Wilson
Functional Characterization of Drosophila melanogaster Peptide O-Xylosyltransferase, the Key Enzyme for Proteoglycan Chain Initiation and Member of the Core 2/I N-Acetylglucosaminyltransferase Family
J. Biol. Chem. 2002 277: 21207-21212. First Published on April 2, 2002; doi:10.1074/jbc.M201634200 [Abstract] [Full Text] [PDF]  

Sarah L. Dallas, Jennifer L. Rosser, Gregory R. Mundy, and Lynda F. Bonewald
Proteolysis of Latent Transforming Growth Factor-beta (TGF-beta )-binding Protein-1 by Osteoclasts. A CELLULAR MECHANISM FOR RELEASE OF TGF-beta FROM BONE MATRIX
J. Biol. Chem. 2002 277: 21352-21360. First Published on April 2, 2002; doi:10.1074/jbc.M111663200 [Abstract] [Full Text] [PDF]  

Toshio Ninomiya, Nobuo Sugiura, Akira Tawada, Kazunori Sugimoto, Hideto Watanabe, and Koji Kimata
Molecular Cloning and Characterization of Chondroitin Polymerase from Escherichia coli Strain K4
J. Biol. Chem. 2002 277: 21567-21575. First Published on April 9, 2002; doi:10.1074/jbc.M201719200 [Abstract] [Full Text] [PDF]  

Philip E. Pummill and Paul L. DeAngelis
Evaluation of Critical Structural Elements of UDP-Sugar Substrates and Certain Cysteine Residues of a Vertebrate Hyaluronan Synthase
J. Biol. Chem. 2002 277: 21610-21616. First Published on April 9, 2002; doi:10.1074/jbc.M202456200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:Back

Xiaoping Li, Horng-Yuan Kan, Sophia Lavrentiadou, Monty Krieger, and Vassilis Zannis
Reconstituted Discoidal ApoE-Phospholipid Particles Are Ligands for the Scavenger Receptor BI. THE AMINO-TERMINAL 1-165 DOMAIN OF ApoE SUFFICES FOR RECEPTOR BINDING
J. Biol. Chem. 2002 277: 21149-21157. First Published on February 22, 2002; doi:10.1074/jbc.M200658200 [Abstract] [Full Text] [PDF]  

Robert V. Diemel, Margot M. E. Snel, Alan J. Waring, Frans J. Walther, Lambert M. G. van Golde, Günther Putz, Henk P. Haagsman, and Joseph J. Batenburg
Multilayer Formation upon Compression of Surfactant Monolayers Depends on Protein Concentration as Well as Lipid Composition. AN ATOMIC FORCE MICROSCOPY STUDY
J. Biol. Chem. 2002 277: 21179-21188. First Published on March 28, 2002; doi:10.1074/jbc.M111758200 [Abstract] [Full Text] [PDF]  

Takamitsu Sano, Daniel Baker, Tamas Virag, Atsushi Wada, Yutaka Yatomi, Tetsuyuki Kobayashi, Yasuyuki Igarashi, and Gabor Tigyi
Multiple Mechanisms Linked to Platelet Activation Result in Lysophosphatidic Acid and Sphingosine 1-Phosphate Generation in Blood
J. Biol. Chem. 2002 277: 21197-21206. First Published on April 2, 2002; doi:10.1074/jbc.M201289200 [Abstract] [Full Text] [PDF]  

Richard B. Weinberg, Rachel A. Anderson, Victoria R. Cook, Florence Emmanuel, Patrice Denèfle, Alan R. Tall, and Armin Steinmetz
Interfacial Exclusion Pressure Determines the Ability of Apolipoprotein A-IV Truncation Mutants to Activate Cholesterol Ester Transfer Protein
J. Biol. Chem. 2002 277: 21549-21553. First Published on April 8, 2002; doi:10.1074/jbc.M202197200 [Abstract] [Full Text] [PDF]  

Tong Liu, Monty Krieger, Horng-Yuan Kan, and Vassilis I. Zannis
The Effects of Mutations in Helices 4 and 6 of ApoA-I on Scavenger Receptor Class B Type I (SR-BI)-mediated Cholesterol Efflux Suggest That Formation of a Productive Complex between Reconstituted High Density Lipoprotein and SR-BI Is Required for Efficient Lipid Transport
J. Biol. Chem. 2002 277: 21576-21584. First Published on March 6, 2002; doi:10.1074/jbc.M112103200 [Abstract] [Full Text] [PDF]  

K. Aftab Rashid, Sarah Hevi, Yin Chen, Françoise Le Cahérec, and Steven L. Chuck
A Proteomic Approach Identifies Proteins in Hepatocytes That Bind Nascent Apolipoprotein B
J. Biol. Chem. 2002 277: 22010-22017. First Published on April 4, 2002; doi:10.1074/jbc.M112448200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:Back

Angelos-Aristeidis Konstas, Michael Dabrowski, Christoph Korbmacher, and Stephen J. Tucker
Intrinsic Sensitivity of Kir1.1 (ROMK) to Glibenclamide in the Absence of SUR2B. IMPLICATIONS FOR THE IDENTITY OF THE RENAL ATP-REGULATED SECRETORY K+ CHANNEL
J. Biol. Chem. 2002 277: 21346-21351. First Published on April 1, 2002; doi:10.1074/jbc.M202005200 [Abstract] [Full Text] [PDF]  

Frank Baumann, Walter Neupert, and Johannes M. Herrmann
Insertion of Bitopic Membrane Proteins into the Inner Membrane of Mitochondria Involves an Export Step from the Matrix
J. Biol. Chem. 2002 277: 21405-21413. First Published on April 3, 2002; doi:10.1074/jbc.M201670200 [Abstract] [Full Text] [PDF]  

Marco A. Sanchez, Rob Tryon, Joy Green, Ilja Boor, and Scott M. Landfear
Six Related Nucleoside/Nucleobase Transporters from Trypanosoma brucei Exhibit Distinct Biochemical Functions
J. Biol. Chem. 2002 277: 21499-21504. First Published on April 5, 2002; doi:10.1074/jbc.M202319200 [Abstract] [Full Text] [PDF]  

Petra Scholze, Lene Nørregaard, Ernst A. Singer, Michael Freissmuth, Ulrik Gether, and Harald H. Sitte
The Role of Zinc Ions in Reverse Transport Mediated by Monoamine Transporters
J. Biol. Chem. 2002 277: 21505-21513. First Published on April 8, 2002; doi:10.1074/jbc.M112265200 [Abstract] [Full Text] [PDF]  

Tatiana Suárez, Subhasis B. Biswas, and Esther E. Biswas
Biochemical Defects in Retina-specific Human ATP Binding Cassette Transporter Nucleotide Binding Domain 1 Mutants Associated with Macular Degeneration
J. Biol. Chem. 2002 277: 21759-21767. First Published on March 27, 2002; doi:10.1074/jbc.M202053200 [Abstract] [Full Text] [PDF]  

Asier Sáez-Cirión, Shlomo Nir, Maier Lorizate, Aitziber Agirre, Antonio Cruz, Jesús Pérez-Gil, and José L. Nieva
Sphingomyelin and Cholesterol Promote HIV-1 gp41 Pretransmembrane Sequence Surface Aggregation and Membrane Restructuring
J. Biol. Chem. 2002 277: 21776-21785. First Published on April 2, 2002; doi:10.1074/jbc.M202255200 [Abstract] [Full Text] [PDF]  

Eva Loh and Wanjin Hong
Sec34 Is Implicated in Traffic from the Endoplasmic Reticulum to the Golgi and Exists in a Complex with GTC-90 and ldlBp
J. Biol. Chem. 2002 277: 21955-21961. First Published on April 2, 2002; doi:10.1074/jbc.M202326200 [Abstract] [Full Text] [PDF]  

Ruslan N. Grishanin, Vadim A. Klenchin, Kelly M. Loyet, Judith A. Kowalchyk, Kyoungsook Ann, and Thomas F. J. Martin
Membrane Association Domains in Ca2+-dependent Activator Protein for Secretion Mediate Plasma Membrane and Dense-core Vesicle Binding Required for Ca2+-dependent Exocytosis
J. Biol. Chem. 2002 277: 22025-22034. First Published on April 1, 2002; doi:10.1074/jbc.M201614200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:Back

Paulo C. Rodriguez, Arnold H. Zea, Kirk S. Culotta, Jovanny Zabaleta, Juan B. Ochoa, and Augusto C. Ochoa
Regulation of T Cell Receptor CD3zeta Chain Expression by L-Arginine
J. Biol. Chem. 2002 277: 21123-21129. First Published on April 11, 2002; doi:10.1074/jbc.M110675200 [Abstract] [Full Text] [PDF]  

Armelle Yart, Serge Roche, Reinhard Wetzker, Muriel Laffargue, Nicholas Tonks, Patrick Mayeux, Hugues Chap, and Patrick Raynal
A Function for Phosphoinositide 3-Kinase beta Lipid Products in Coupling beta gamma to Ras Activation in Response to Lysophosphatidic Acid
J. Biol. Chem. 2002 277: 21167-21178. First Published on March 26, 2002; doi:10.1074/jbc.M110411200 [Abstract] [Full Text] [PDF]  

Dayanand D. Deo, T. William Axelrad, Everett G. Robert, Victor Marcheselli, Nicolas G. Bazan, and Jay D. Hunt
Phosphorylation of STAT-3 in Response to Basic Fibroblast Growth Factor Occurs through a Mechanism Involving Platelet-activating Factor, JAK-2, and Src in Human Umbilical Vein Endothelial Cells. EVIDENCE FOR A DUAL KINASE MECHANISM
J. Biol. Chem. 2002 277: 21237-21245. First Published on April 8, 2002; doi:10.1074/jbc.M110955200 [Abstract] [Full Text] [PDF]  

Ji-Sook Hahn and Dennis J. Thiele
Regulation of the Saccharomyces cerevisiae Slt2 Kinase Pathway by the Stress-inducible Sdp1 Dual Specificity Phosphatase
J. Biol. Chem. 2002 277: 21278-21284. First Published on March 28, 2002; doi:10.1074/jbc.M202557200 [Abstract] [Full Text] [PDF]  

Zsolt Balla, Brigitte Hoch, Peter Karczewski, and Ingolf E. Blasig
Calcium/Calmodulin-dependent Protein Kinase IIdelta 2 and gamma Isoforms Regulate Potassium Currents of Rat Brain Capillary Endothelial Cells under Hypoxic Conditions
J. Biol. Chem. 2002 277: 21306-21314. First Published on March 29, 2002; doi:10.1074/jbc.M200553200 [Abstract] [Full Text] [PDF]  

Megan Fabbro, Jose A. Rodriguez, Richard Baer, and Beric R. Henderson
BARD1 Induces BRCA1 Intranuclear Foci Formation by Increasing RING-dependent BRCA1 Nuclear Import and Inhibiting BRCA1 Nuclear Export
J. Biol. Chem. 2002 277: 21315-21324. First Published on March 29, 2002; doi:10.1074/jbc.M200769200 [Abstract] [Full Text] [PDF]  

Salil K. Ghosh, Laxmisilpa Gadiparthi, Zhao-Zhu Zeng, Manjula Bhanoori, Carmen Tellez, Menashe Bar-Eli, and Gadiparthi N. Rao
ATF-1 Mediates Protease-activated Receptor-1 but Not Receptor Tyrosine Kinase-induced DNA Synthesis in Vascular Smooth Muscle Cells
J. Biol. Chem. 2002 277: 21325-21331. First Published on March 29, 2002; doi:10.1074/jbc.M201608200 [Abstract] [Full Text] [PDF]  

Chuan-Ming Hao, Reyadh Redha, Jason Morrow, and Matthew D. Breyer
Peroxisome Proliferator-activated Receptor delta Activation Promotes Cell Survival following Hypertonic Stress
J. Biol. Chem. 2002 277: 21341-21345. First Published on April 1, 2002; doi:10.1074/jbc.M200695200 [Abstract] [Full Text] [PDF]  

Dongmin Liu and Joseph S. Dillon
Dehydroepiandrosterone Activates Endothelial Cell Nitric-oxide Synthase by a Specific Plasma Membrane Receptor Coupled to Galpha i2,3
J. Biol. Chem. 2002 277: 21379-21388. First Published on April 4, 2002; doi:10.1074/jbc.M200491200 [Abstract] [Full Text] [PDF]  

Feng Lin, Siva Kumar Kolluri, Guo-quan Chen, and Xiao-kun Zhang
Regulation of Retinoic Acid-induced Inhibition of AP-1 Activity by Orphan Receptor Chicken Ovalbumin Upstream Promoter-Transcription Factor
J. Biol. Chem. 2002 277: 21414-21422. First Published on April 4, 2002; doi:10.1074/jbc.M201885200 [Abstract] [Full Text] [PDF]  

Yoshiya Tanaka, Shingo Nakayamada, Hiroko Fujimoto, Yosuke Okada, Hisanori Umehara, Tohru Kataoka, and Yasuhiro Minami
H-Ras/Mitogen-activated Protein Kinase Pathway Inhibits Integrin-mediated Adhesion and Induces Apoptosis in Osteoblasts
J. Biol. Chem. 2002 277: 21446-21452. First Published on April 4, 2002; doi:10.1074/jbc.M202238200 [Abstract] [Full Text] [PDF]  

Volker Brinkmann, Michael D. Davis, Christopher E. Heise, Rainer Albert, Sylvain Cottens, Robert Hof, Christian Bruns, Eva Prieschl, Thomas Baumruker, Peter Hiestand, Carolyn A. Foster, Markus Zollinger, and Kevin R. Lynch
The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors
J. Biol. Chem. 2002 277: 21453-21457. First Published on April 19, 2002; doi:10.1074/jbc.C200176200 [Abstract] [Full Text] [PDF]  

Anna Bagorda, Lorenzo Guerra, Francesca Di Sole, Corinna Hemle-Kolb, Rosa A. Cardone, Teresa Fanelli, Stephan J. Reshkin, Serge M. Gisler, Heini Murer, and Valeria Casavola
Reciprocal Protein Kinase A Regulatory Interactions between Cystic Fibrosis Transmembrane Conductance Regulator and Na+/H+ Exchanger Isoform 3 in a Renal Polarized Epithelial Cell Model
J. Biol. Chem. 2002 277: 21480-21488. First Published on April 5, 2002; doi:10.1074/jbc.M112245200 [Abstract] [Full Text] [PDF]  

Mohammed A. Ayoub, Cyril Couturier, Estelle Lucas-Meunier, Stephane Angers, Philippe Fossier, Michel Bouvier, and Ralf Jockers
Monitoring of Ligand-independent Dimerization and Ligand-induced Conformational Changes of Melatonin Receptors in Living Cells by Bioluminescence Resonance Energy Transfer
J. Biol. Chem. 2002 277: 21522-21528. First Published on April 8, 2002; doi:10.1074/jbc.M200729200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Zipora Borovsky, Galit Mishan-Eisenberg, Einat Yaniv, and Jacob Rachmilewitz
Serial Triggering of T Cell Receptors Results in Incremental Accumulation of Signaling Intermediates
J. Biol. Chem. 2002 277: 21529-21536. First Published on April 8, 2002; doi:10.1074/jbc.M201613200 [Abstract] [Full Text] [PDF]  

Geneviève Lachance, Sylvain Levasseur, and Paul H. Naccache
Chemotactic Factor-induced Recruitment and Activation of Tec Family Kinases in Human Neutrophils. IMPLICATION OF PHOSPHATIDYLINOSITOL 3-KINASES
J. Biol. Chem. 2002 277: 21537-21541. First Published on April 8, 2002; doi:10.1074/jbc.M201903200 [Abstract] [Full Text] [PDF]  

Katsue Suzuki-Inoue, David Tulasne, Yang Shen, Teresa Bori-Sanz, Osamu Inoue, Stephanie M. Jung, Masaaki Moroi, Robert K. Andrews, Michael C. Berndt, and Steve P. Watson
Association of Fyn and Lyn with the Proline-rich Domain of Glycoprotein VI Regulates Intracellular Signaling
J. Biol. Chem. 2002 277: 21561-21566. First Published on April 9, 2002; doi:10.1074/jbc.M201012200 [Abstract] [Full Text] [PDF]  

Mohamed Trebak, Gary St. J. Bird, Richard R. McKay, and James W. Putney, Jr.
Comparison of Human TRPC3 Channels in Receptor-activated and Store-operated Modes. DIFFERENTIAL SENSITIVITY TO CHANNEL BLOCKERS SUGGESTS FUNDAMENTAL DIFFERENCES IN CHANNEL COMPOSITION
J. Biol. Chem. 2002 277: 21617-21623. First Published on April 9, 2002; doi:10.1074/jbc.M202549200 [Abstract] [Full Text] [PDF]  

David W. Powell, Madhavi J. Rane, Qingdan Chen, Saurabh Singh, and Kenneth R. McLeish
Identification of 14-3-3zeta as a Protein Kinase B/Akt Substrate
J. Biol. Chem. 2002 277: 21639-21642. First Published on April 15, 2002; doi:10.1074/jbc.M203167200 [Abstract] [Full Text] [PDF]  

Márta Szaszák, Zsuzsanna Gáborik, Gábor Turu, Peter S. McPherson, Adrian J. L. Clark, Kevin J. Catt, and László Hunyady
Role of the Proline-rich Domain of Dynamin-2 and Its Interactions with Src Homology 3 Domains during Endocytosis of the AT1 Angiotensin Receptor
J. Biol. Chem. 2002 277: 21650-21656. First Published on March 29, 2002; doi:10.1074/jbc.M200778200 [Abstract] [Full Text] [PDF]  

Janet Y. Leung, Frank T. Kolligs, Rong Wu, Yali Zhai, Rork Kuick, Samir Hanash, Kathleen R. Cho, and Eric R. Fearon
Activation of AXIN2 Expression by beta -Catenin-T Cell Factor. A FEEDBACK REPRESSOR PATHWAY REGULATING Wnt SIGNALING
J. Biol. Chem. 2002 277: 21657-21665. First Published on April 8, 2002; doi:10.1074/jbc.M200139200 [Abstract] [Full Text] [PDF]  

Wenli Wang, Chengyu Z. Prince, Yongshan Mou, and Matthew J. Pollman
Notch3 Signaling in Vascular Smooth Muscle Cells Induces c-FLIP Expression via ERK/MAPK Activation. RESISTANCE TO Fas LIGAND-INDUCED APOPTOSIS
J. Biol. Chem. 2002 277: 21723-21729. First Published on March 29, 2002; doi:10.1074/jbc.M202224200 [Abstract] [Full Text] [PDF]  

Maria Filippova, Helen Song, Jodi L. Connolly, Terence S. Dermody, and Penelope J. Duerksen-Hughes
The Human Papillomavirus 16 E6 Protein Binds to Tumor Necrosis Factor (TNF) R1 and Protects Cells from TNF-induced Apoptosis
J. Biol. Chem. 2002 277: 21730-21739. First Published on April 4, 2002; doi:10.1074/jbc.M200113200 [Abstract] [Full Text] [PDF]  

David A. Calderwood, Boxu Yan, Jose M. de Pereda, Begoña García Alvarez, Yosuke Fujioka, Robert C. Liddington, and Mark H. Ginsberg
The Phosphotyrosine Binding-like Domain of Talin Activates Integrins
J. Biol. Chem. 2002 277: 21749-21758. First Published on April 3, 2002; doi:10.1074/jbc.M111996200 [Abstract] [Full Text] [PDF]  

Rammohan V. Rao, Susana Castro-Obregon, Harald Frankowski, Martin Schuler, Veronica Stoka, Gabriel del Rio, Dale E. Bredesen, and H. Michael Ellerby
Coupling Endoplasmic Reticulum Stress to the Cell Death Program. AN Apaf-1-INDEPENDENT INTRINSIC PATHWAY
J. Biol. Chem. 2002 277: 21836-21842. First Published on March 27, 2002; doi:10.1074/jbc.M202726200 [Abstract] [Full Text] [PDF]  

Yoko Ogawara, Shohei Kishishita, Toshiyuki Obata, Yuko Isazawa, Toshiaki Suzuki, Keiji Tanaka, Norihisa Masuyama, and Yukiko Gotoh
Akt Enhances Mdm2-mediated Ubiquitination and Degradation of p53
J. Biol. Chem. 2002 277: 21843-21850. First Published on March 28, 2002; doi:10.1074/jbc.M109745200 [Abstract] [Full Text] [PDF]  

Xin-Min Zheng, Ross J. Resnick, and David Shalloway
Mitotic Activation of Protein-tyrosine Phosphatase alpha and Regulation of Its Src-mediated Transforming Activity by Its Sites of Protein Kinase C Phosphorylation
J. Biol. Chem. 2002 277: 21922-21929. First Published on March 28, 2002; doi:10.1074/jbc.M201394200 [Abstract] [Full Text] [PDF]  

Hiroshi Kishi, Hanumanthappa Krishnamurthy, Colette Galet, Ravi Sankar Bhaskaran, and Mario Ascoli
Identification of a Short Linear Sequence Present in the C-terminal Tail of the Rat Follitropin Receptor That Modulates Arrestin-3 Binding in a Phosphorylation-independent Fashion
J. Biol. Chem. 2002 277: 21939-21946. First Published on April 4, 2002; doi:10.1074/jbc.M110894200 [Abstract] [Full Text] [PDF]  

Laurence Aubry, Sara Mattei, Béatrice Blot, Rémy Sadoul, Michel Satre, and Gérard Klein
Biochemical Characterization of Two Analogues of the Apoptosis-linked Gene 2 Protein in Dictyostelium discoideum and Interaction with a Physiological Partner in Mammals, Murine Alix
J. Biol. Chem. 2002 277: 21947-21954. First Published on April 1, 2002; doi:10.1074/jbc.M201718200 [Abstract] [Full Text] [PDF]  

Tiina Kainulainen, Alexandra Pender, Mario D'Addario, Yuanyi Feng, Predrag Lekic, and Christopher A. McCulloch
Cell Death and Mechanoprotection by Filamin A in Connective Tissues after Challenge by Applied Tensile Forces
J. Biol. Chem. 2002 277: 21998-22009. First Published on March 21, 2002; doi:10.1074/jbc.M200715200 [Abstract] [Full Text] [PDF]  

Jun Chen, Sunil Kaul, and S. Stoney Simons, Jr.
Structure/Activity Elements of the Multifunctional Protein, GMEB-1. CHARACTERIZATION OF DOMAINS RELEVANT FOR THE MODULATION OF GLUCOCORTICOID RECEPTOR TRANSACTIVATION PROPERTIES
J. Biol. Chem. 2002 277: 22053-22062. First Published on April 4, 2002; doi:10.1074/jbc.M202311200 [Abstract] [Full Text] [PDF]  

Arnaud Besson, Tammy L. Wilson, and V. Wee Yong
The Anchoring Protein RACK1 Links Protein Kinase Cepsilon to Integrin beta Chains. REQUIREMENT FOR ADHESION AND MOTILITY
J. Biol. Chem. 2002 277: 22073-22084. First Published on April 4, 2002; doi:10.1074/jbc.M111644200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:Back

Victor T. Solovyan, Zinayida A. Bezvenyuk, Antero Salminen, Caroline A. Austin, and Michael J. Courtney
The Role of Topoisomerase II in the Excision of DNA Loop Domains during Apoptosis
J. Biol. Chem. 2002 277: 21458-21467. First Published on April 8, 2002; doi:10.1074/jbc.M110621200 [Abstract] [Full Text] [PDF]  

Ying Xu and Ronald L. Mellgren
Calpain Inhibition Decreases the Growth Rate of Mammalian Cell Colonies
J. Biol. Chem. 2002 277: 21474-21479. First Published on April 5, 2002; doi:10.1074/jbc.M111689200 [Abstract] [Full Text] [PDF]  

M. Carmen Carmona, Roser Iglesias, María-Jesús Obregón, Gretchen J. Darlington, Francesc Villarroya, and Marta Giralt
Mitochondrial Biogenesis and Thyroid Status Maturation in Brown Fat Require CCAAT/Enhancer-binding Protein alpha
J. Biol. Chem. 2002 277: 21489-21498. First Published on April 8, 2002; doi:10.1074/jbc.M201710200 [Abstract] [Full Text] [PDF]  

Mónica Montero-Lomelí, Bruno L. B. Morais, Daniela L. Figueiredo, Domingos C. S. Neto, João R. P. Martins, and Claudio A. Masuda
The Initiation Factor eIF4A Is Involved in the Response to Lithium Stress in Saccharomyces cerevisiae
J. Biol. Chem. 2002 277: 21542-21548. First Published on April 8, 2002; doi:10.1074/jbc.M201977200 [Abstract] [Full Text] [PDF]  

Zhong-Sheng Ji, R. Dennis Miranda, Yvonne M. Newhouse, Karl H. Weisgraber, Yadong Huang, and Robert W. Mahley
Apolipoprotein E4 Potentiates Amyloid beta Peptide-induced Lysosomal Leakage and Apoptosis in Neuronal Cells
J. Biol. Chem. 2002 277: 21821-21828. First Published on March 23, 2002; doi:10.1074/jbc.M112109200 [Abstract] [Full Text] [PDF]  

Molly A. Accola, Bing Huang, Azzah Al Masri, and Mark A. McNiven
The Antiviral Dynamin Family Member, MxA, Tubulates Lipids and Localizes to the Smooth Endoplasmic Reticulum
J. Biol. Chem. 2002 277: 21829-21835. First Published on March 26, 2002; doi:10.1074/jbc.M201641200 [Abstract] [Full Text] [PDF]  

Jan Pilch, Rolf Habermann, and Brunhilde Felding-Habermann
Unique Ability of Integrin alpha vbeta 3 to Support Tumor Cell Arrest under Dynamic Flow Conditions
J. Biol. Chem. 2002 277: 21930-21938. First Published on April 4, 2002; doi:10.1074/jbc.M201630200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Toru Amano, Noriko Kaji, Kazumasa Ohashi, and Kensaku Mizuno
Mitosis-specific Activation of LIM Motif-containing Protein Kinase and Roles of Cofilin Phosphorylation and Dephosphorylation in Mitosis
J. Biol. Chem. 2002 277: 22093-22102. First Published on March 29, 2002; doi:10.1074/jbc.M201444200 [Abstract] [Full Text] [PDF]  


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