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Other Issues:
 Table of Contents: Aug 2 2002; 277 (31)   [Index by Author]  [Cover Figure and Caption]
       Classics
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Genomics Proteomics and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Classics:

The Structure and Function of Hemoglobin: Gilbert Smithson Adair and the Adair Equations
The Hemoglobin System. VI. The Oxygen Dissociation Curve of Hemoglobin (G. S. Adair, A. V. Bock, and H. Field J. Biol. Chem. 63, 529-545)
J. Biol. Chem. 2002 277: 20. [Full Text]  

Accelerated Publications:

John D. Bishop and Jill M. Schumacher
Phosphorylation of the Carboxyl Terminus of Inner Centromere Protein (INCENP) by the Aurora B Kinase Stimulates Aurora B Kinase Activity
J. Biol. Chem. 2002 277: 27577-27580. First Published on June 4, 2002; 10.1074/jbc.C200307200 [Abstract] [Full Text] [PDF]  

Andras Gruber, Angelene M. Cantwell, Enrico Di Cera, and Stephen R. Hanson
The Thrombin Mutant W215A/E217A Shows Safe and Potent Anticoagulant and Antithrombotic Effects in Vivo
J. Biol. Chem. 2002 277: 27581-27584. First Published on June 17, 2002; 10.1074/jbc.C200237200 [Abstract] [Full Text] [PDF]  

Tip W. Loo, M. Claire Bartlett, and David M. Clarke
Introduction of the Most Common Cystic Fibrosis Mutation (Delta F508) into Human P-glycoprotein Disrupts Packing of the Transmembrane Segments
J. Biol. Chem. 2002 277: 27585-27588. First Published on June 17, 2002; 10.1074/jbc.C200330200 [Abstract] [Full Text] [PDF]  

Sonia A. Cunningham, Jose M. Rodriguez, M. Pia Arrate, Tuan M. Tran, and Tommy A. Brock
JAM2 Interacts with alpha 4beta 1. FACILITATION BY JAM3
J. Biol. Chem. 2002 277: 27589-27592. First Published on June 17, 2002; 10.1074/jbc.C200331200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Masayuki Yamada, Noriko Sato, Chika Taniyama, Kiyoshi Ohtani, Ken-ichi Arai, and Hisao Masai
A 63-Base Pair DNA Segment Containing an Sp1 Site but Not a Canonical E2F Site Can Confer Growth-dependent and E2F-mediated Transcriptional Stimulation of the Human ASK Gene Encoding the Regulatory Subunit for Human Cdc7-related Kinase
J. Biol. Chem. 2002 277: 27668-27681. First Published on May 15, 2002; 10.1074/jbc.M202884200 [Abstract] [Full Text] [PDF]  

Aleksandra Germaniuk, Krzysztof Liberek, and Jaroslaw Marszalek
A Bichaperone (Hsp70-Hsp78) System Restores Mitochondrial DNA Synthesis following Thermal Inactivation of Mip1p Polymerase
J. Biol. Chem. 2002 277: 27801-27808. First Published on May 21, 2002; 10.1074/jbc.M201756200 [Abstract] [Full Text] [PDF]  

Takuro Nakagawa and Richard D. Kolodner
The MER3 DNA Helicase Catalyzes the Unwinding of Holliday Junctions
J. Biol. Chem. 2002 277: 28019-28024. First Published on May 30, 2002; 10.1074/jbc.M204165200 [Abstract] [Full Text] [PDF]  

Tomoko Ohya, Yasuo Kawasaki, Shin-Ichiro Hiraga, Sakie Kanbara, Kou Nakajo, Naomi Nakashima, Akiko Suzuki, and Akio Sugino
The DNA Polymerase Domain of polepsilon Is Required for Rapid, Efficient, and Highly Accurate Chromosomal DNA Replication, Telomere Length Maintenance, and Normal Cell Senescence in Saccharomyces cerevisiae
J. Biol. Chem. 2002 277: 28099-28108. First Published on May 15, 2002; 10.1074/jbc.M111573200 [Abstract] [Full Text] [PDF]  

Olga Potapova, Nigel D. F. Grindley, and Catherine M. Joyce
The Mutational Specificity of the Dbh Lesion Bypass Polymerase and Its Implications
J. Biol. Chem. 2002 277: 28157-28166. First Published on May 21, 2002; 10.1074/jbc.M202607200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Stephane Konig, James Burkman, Julie Fitzgerald, Marilyn Mitchell, Leonard Su, and Hansell Stedman
Modular Organization of Phylogenetically Conserved Domains Controlling Developmental Regulation of the Human Skeletal Myosin Heavy Chain Gene Family
J. Biol. Chem. 2002 277: 27593-27605. First Published on April 23, 2002; 10.1074/jbc.M203162200 [Abstract] [Full Text] [PDF]  

Luis A. Jurado, Shulan Song, William J. Roesler, and Edwards A. Park
Conserved Amino Acids within CCAAT Enhancer-binding Proteins (C/EBPalpha and beta ) Regulate Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression
J. Biol. Chem. 2002 277: 27606-27612. First Published on May 7, 2002; 10.1074/jbc.M201429200 [Abstract] [Full Text] [PDF]  

Herbert M. van Wering, Inge L. Huibregtse, Sanne M. van der Zwan, Maartje S. de Bie, Lauren N. Dowling, François Boudreau, Edmond H. H. M. Rings, Richard J. Grand, and Stephen D. Krasinski
Physical Interaction between GATA-5 and Hepatocyte Nuclear Factor-1alpha Results in Synergistic Activation of the Human Lactase-Phlorizin Hydrolase Promoter
J. Biol. Chem. 2002 277: 27659-27667. First Published on May 14, 2002; 10.1074/jbc.M203645200 [Abstract] [Full Text] [PDF]  

Joseph Koipally and Katia Georgopoulos
A Molecular Dissection of the Repression Circuitry of Ikaros
J. Biol. Chem. 2002 277: 27697-27705. First Published on May 15, 2002; 10.1074/jbc.M201694200 [Abstract] [Full Text] [PDF]  

Daeyoup Lee, Hak-Zoo Kim, Kwi Wan Jeong, Young Sam Shim, Izumi Horikawa, J. Carl Barrett, and Joonho Choe
Human Papillomavirus E2 Down-regulates the Human Telomerase Reverse Transcriptase Promoter
J. Biol. Chem. 2002 277: 27748-27756. First Published on May 17, 2002; 10.1074/jbc.M203706200 [Abstract] [Full Text] [PDF]  

Dongping Li, Huifen Zhu, Kunfan Liu, Xin Liu, Georg Leggewie, Michael Udvardi, and Daowen Wang
Purple Acid Phosphatases of Arabidopsis thaliana. COMPARATIVE ANALYSIS AND DIFFERENTIAL REGULATION BY PHOSPHATE DEPRIVATION
J. Biol. Chem. 2002 277: 27772-27781. First Published on May 20, 2002; 10.1074/jbc.M204183200 [Abstract] [Full Text] [PDF]  

Britta M. Jacobsen, Jennifer K. Richer, Stephanie A. Schittone, and Kathryn B. Horwitz
New Human Breast Cancer Cells to Study Progesterone Receptor Isoform Ratio Effects and Ligand-independent Gene Regulation
J. Biol. Chem. 2002 277: 27793-27800. First Published on May 20, 2002; 10.1074/jbc.M202584200 [Abstract] [Full Text] [PDF]  

Simona Volpi, Cristina Rabadan-Diehl, Niamh Cawley, and Greti Aguilera
Transcriptional Regulation of the Pituitary Vasopressin V1b Receptor Involves a GAGA-binding Protein
J. Biol. Chem. 2002 277: 27829-27838. First Published on May 21, 2002; 10.1074/jbc.M201508200 [Abstract] [Full Text] [PDF]  

Vasudevan Seshadri, Paul L. Fox, and Chinmay K. Mukhopadhyay
Dual Role of Insulin in Transcriptional Regulation of the Acute Phase Reactant Ceruloplasmin
J. Biol. Chem. 2002 277: 27903-27911. First Published on May 23, 2002; 10.1074/jbc.M203610200 [Abstract] [Full Text] [PDF]  

Julio E. Ayala, Ryan S. Streeper, Christina A. Svitek, Joshua K. Goldman, James K. Oeser, and Richard M. O'Brien
Accessory Elements, Flanking DNA Sequence, and Promoter Context Play Key Roles in Determining the Efficacy of Insulin and Phorbol Ester Signaling through the Malic Enzyme and Collagenase-1 AP-1 Motifs
J. Biol. Chem. 2002 277: 27935-27944. First Published on May 24, 2002; 10.1074/jbc.M203682200 [Abstract] [Full Text] [PDF]  

Naohiro Hori, Hiroshi Nakano, Toshiyuki Takeuchi, Hiroyuki Kato, Sayuri Hamaguchi, Mitsuo Oshimura, and Kenzo Sato
A Dyad Oct-binding Sequence Functions as a Maintenance Sequence for the Unmethylated State within the H19/Igf2-imprinted Control Region
J. Biol. Chem. 2002 277: 27960-27967. First Published on May 23, 2002; 10.1074/jbc.M202280200 [Abstract] [Full Text] [PDF]  

Mónica Olivares, José Luis García-Pérez, M. Carmen Thomas, Sara R. Heras, and Manuel C. López
The Non-LTR (Long Terminal Repeat) Retrotransposon L1Tc from Trypanosoma cruzi Codes for a Protein with RNase H Activity
J. Biol. Chem. 2002 277: 28025-28030. First Published on May 30, 2002; 10.1074/jbc.M202896200 [Abstract] [Full Text] [PDF]  

Yan Zhang, Takashi Miki, Toshihiko Iwanaga, Yoko Koseki, Masaaki Okuno, Yasuhiro Sunaga, Nobuaki Ozaki, Hideki Yano, Haruhiko Koseki, and Susumu Seino
Identification, Tissue Expression, and Functional Characterization of Otx3, a Novel Member of the Otx Family
J. Biol. Chem. 2002 277: 28065-28069. First Published on June 7, 2002; 10.1074/jbc.C100767200 [Abstract] [Full Text] [PDF]  

Mark A. Karlok, Sei-Heon Jang, and Judith A. Jaehning
Mutations in the Yeast Mitochondrial RNA Polymerase Specificity Factor, Mtf1, Verify an Essential Role in Promoter Utilization
J. Biol. Chem. 2002 277: 28143-28149. First Published on May 20, 2002; 10.1074/jbc.M204123200 [Abstract] [Full Text] [PDF]  

Robert Sabatini, Nico Meeuwenoord, Jacques H. van Boom, and Piet Borst
Site-specific Interactions of JBP with Base and Sugar Moieties in Duplex J-DNA. EVIDENCE FOR BOTH MAJOR AND MINOR GROOVE CONTACTS
J. Biol. Chem. 2002 277: 28150-28156. First Published on May 23, 2002; 10.1074/jbc.M201487200 [Abstract] [Full Text] [PDF]  

Normand Beaulieu, Steves Morin, Ian C. Chute, Marie-France Robert, Hannah Nguyen, and A. Robert MacLeod
An Essential Role for DNA Methyltransferase DNMT3B in Cancer Cell Survival
J. Biol. Chem. 2002 277: 28176-28181. First Published on May 15, 2002; 10.1074/jbc.M204734200 [Abstract] [Full Text] [PDF]  

Erika Krasnickas Keeton, Terace M. Fletcher, Christopher T. Baumann, Gordon L. Hager, and Catharine L. Smith
Glucocorticoid Receptor Domain Requirements for Chromatin Remodeling and Transcriptional Activation of the Mouse Mammary Tumor Virus Promoter in Different Nucleoprotein Contexts
J. Biol. Chem. 2002 277: 28247-28255. First Published on May 23, 2002; 10.1074/jbc.M203898200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Andrea C. Beckel-Mitchener, Angel Miera, Rebecca Keller, and Nora I. Perrone-Bizzozero
Poly(A) Tail Length-dependent Stabilization of GAP-43 mRNA by the RNA-binding Protein HuD
J. Biol. Chem. 2002 277: 27996-28002. First Published on May 28, 2002; 10.1074/jbc.M201982200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Christine Farrar and Steven Clarke
Altered Levels of S-Adenosylmethionine and S-Adenosylhomocysteine in the Brains of L-Isoaspartyl (D-Aspartyl) O-Methyltransferase-deficient Mice
J. Biol. Chem. 2002 277: 27856-27863. First Published on May 22, 2002; 10.1074/jbc.M203911200 [Abstract] [Full Text] [PDF]  

Atsunori Furuhata, Mitsuhiro Nakamura, Toshihiko Osawa, and Koji Uchida
Thiolation of Protein-bound Carcinogenic Aldehyde. AN ELECTROPHILIC ACROLEIN-LYSINE ADDUCT THAT COVALENTLY BINDS TO THIOLS
J. Biol. Chem. 2002 277: 27919-27926. First Published on May 24, 2002; 10.1074/jbc.M202794200 [Abstract] [Full Text] [PDF]  

Miriam Ellis, Deepak K. Sharma, James D. Hilley, Graham H. Coombs, and Jeremy C. Mottram
Processing and Trafficking of Leishmania mexicana GP63. ANALYSIS USING GPI8 MUTANTS DEFICIENT IN GLYCOSYLPHOSPHATIDYLINOSITOL PROTEIN ANCHORING
J. Biol. Chem. 2002 277: 27968-27974. First Published on May 23, 2002; 10.1074/jbc.M202047200 [Abstract] [Full Text] [PDF]  

Markus Heitzer and Armin Hallmann
An Extracellular Matrix-localized Metalloproteinase with an Exceptional QEXXH Metal Binding Site Prefers Copper for Catalytic Activity
J. Biol. Chem. 2002 277: 28280-28286. First Published on May 28, 2002; 10.1074/jbc.M203925200 [Abstract] [Full Text] [PDF]  

Genomics Proteomics and Bioinformatics:

Nicolas Sabarth, Stefanie Lamer, Ursula Zimny-Arndt, Peter R. Jungblut, Thomas F. Meyer, and Dirk Bumann
Identification of Surface Proteins of Helicobacter pylori by Selective Biotinylation, Affinity Purification, and Two-dimensional Gel Electrophoresis
J. Biol. Chem. 2002 277: 27896-27902. First Published on May 22, 2002; 10.1074/jbc.M204473200 [Abstract] [Full Text] [PDF]  

Markus W. Covert and Bernhard Ø. Palsson
Transcriptional Regulation in Constraints-based Metabolic Models of Escherichia coli
J. Biol. Chem. 2002 277: 28058-28064. First Published on May 10, 2002; 10.1074/jbc.M201691200 [Abstract] [Full Text] [PDF] Supplemental Data  

Protein Structure and Folding:

Anna Balandina, Dmitri Kamashev, and Josette Rouviere-Yaniv
The Bacterial Histone-like Protein HU Specifically Recognizes Similar Structures in All Nucleic Acids. DNA, RNA, AND THEIR HYBRIDS
J. Biol. Chem. 2002 277: 27622-27628. First Published on May 10, 2002; 10.1074/jbc.M201978200 [Abstract] [Full Text] [PDF]  

Guanghua Zhao, Pierpaolo Ceci, Andrea Ilari, Laura Giangiacomo, Thomas M. Laue, Emilia Chiancone, and N. Dennis Chasteen
Iron and Hydrogen Peroxide Detoxification Properties of DNA-binding Protein from Starved Cells. A FERRITIN-LIKE DNA-BINDING PROTEIN OF ESCHERICHIA COLI
J. Biol. Chem. 2002 277: 27689-27696. First Published on May 16, 2002; 10.1074/jbc.M202094200 [Abstract] [Full Text] [PDF]  

Steven J. Kolodziej, Terence Wagenknecht, Dudley K. Strickland, and James K. Stoops
The Three-dimensional Structure of the Human alpha 2-Macroglobulin Dimer Reveals Its Structural Organization in the Tetrameric Native and Chymotrypsin alpha 2-Macroglobulin Complexes
J. Biol. Chem. 2002 277: 28031-28037. First Published on May 15, 2002; 10.1074/jbc.M202714200 [Abstract] [Full Text] [PDF]  

Ning Wu and Emil F. Pai
Crystal Structures of Inhibitor Complexes Reveal an Alternate Binding Mode in Orotidine-5'-monophosphate Decarboxylase
J. Biol. Chem. 2002 277: 28080-28087. First Published on May 13, 2002; 10.1074/jbc.M202362200 [Abstract] [Full Text] [PDF]  

Dun-Sheng Yang, Anurag Tandon, Fusheng Chen, Gang Yu, Haung Yu, Shigeki Arawaka, Hiroshi Hasegawa, Monika Duthie, Stephen D. Schmidt, Triprayer V. Ramabhadran, Ralph A. Nixon, Paul M. Mathews, Samuel E. Gandy, Howard T. J. Mount, Peter St George-Hyslop, and Paul E. Fraser
Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins
J. Biol. Chem. 2002 277: 28135-28142. First Published on May 24, 2002; 10.1074/jbc.M110871200 [Abstract] [Full Text] [PDF] Supplemental Data  

Yoriko Sawano, Tomonari Muramatsu, Ken-ichi Hatano, Koji Nagata, and Masaru Tanokura
Characterization of Genomic Sequence Coding for Bromelain Inhibitors in Pineapple and Expression of Its Recombinant Isoform
J. Biol. Chem. 2002 277: 28222-28227. First Published on May 16, 2002; 10.1074/jbc.M202600200 [Abstract] [Full Text] [PDF]  

Mark J. Jedrzejas, Luciane V. Mello, Bert L. de Groot, and Songlin Li
Mechanism of Hyaluronan Degradation by Streptococcus pneumoniae Hyaluronate Lyase. STRUCTURES OF COMPLEXES WITH THE SUBSTRATE
J. Biol. Chem. 2002 277: 28287-28297. First Published on May 3, 2002; 10.1074/jbc.M112009200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Larry S. Tobacman, Mahta Nihli, Carol Butters, Mark Heller, Victoria Hatch, Roger Craig, William Lehman, and Earl Homsher
The Troponin Tail Domain Promotes a Conformational State of the Thin Filament That Suppresses Myosin Activity
J. Biol. Chem. 2002 277: 27636-27642. First Published on May 14, 2002; 10.1074/jbc.M201768200 [Abstract] [Full Text] [PDF]  

Haruhiko Isawa, Masao Yuda, Yuki Orito, and Yasuo Chinzei
A Mosquito Salivary Protein Inhibits Activation of the Plasma Contact System by Binding to Factor XII and High Molecular Weight Kininogen
J. Biol. Chem. 2002 277: 27651-27658. First Published on May 13, 2002; 10.1074/jbc.M203505200 [Abstract] [Full Text] [PDF]  

Daniel Y. Wu, Douglas C. Tkachuck, Rachel S. Roberson, and William H. Schubach
The Human SNF5/INI1 Protein Facilitates the Function of the Growth Arrest and DNA Damage-inducible Protein (GADD34) and Modulates GADD34-bound Protein Phosphatase-1 Activity
J. Biol. Chem. 2002 277: 27706-27715. First Published on May 16, 2002; 10.1074/jbc.M200955200 [Abstract] [Full Text] [PDF]  

Carol A. Chrestensen and Thomas W. Sturgill
Characterization of the p90 Ribosomal S6 Kinase 2 Carboxyl-terminal Domain as a Protein Kinase
J. Biol. Chem. 2002 277: 27733-27741. First Published on May 16, 2002; 10.1074/jbc.M202663200 [Abstract] [Full Text] [PDF]  

Silas P. Cook, Ismael Galve-Roperh, Álvaro Martínez del Pozo, and Ignacio Rodríguez-Crespo
Direct Calcium Binding Results in Activation of Brain Serine Racemase
J. Biol. Chem. 2002 277: 27782-27792. First Published on May 20, 2002; 10.1074/jbc.M111814200 [Abstract] [Full Text] [PDF]  

Yan Pafumi, Denis Lairon, Paulette Lechene de la Porte, Christine Juhel, Judith Storch, Margit Hamosh, and Martine Armand
Mechanisms of Inhibition of Triacylglycerol Hydrolysis by Human Gastric Lipase
J. Biol. Chem. 2002 277: 28070-28079. First Published on April 8, 2002; 10.1074/jbc.M202839200 [Abstract] [Full Text] [PDF]  

Ester Boix, Yingnan Zhang, G. Jawahar Swaminathan, Keith Brew, and K. Ravi Acharya
Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, alpha -1,3-Galactosyltransferase
J. Biol. Chem. 2002 277: 28310-28318. First Published on May 14, 2002; 10.1074/jbc.M202631200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

David B. Hawkes, Gregory W. Adams, Alma L. Burlingame, Paul R. Ortiz de Montellano, and James J. De Voss
Cytochrome P450cin (CYP176A), Isolation, Expression, and Characterization
J. Biol. Chem. 2002 277: 27725-27732. First Published on May 16, 2002; 10.1074/jbc.M203382200 [Abstract] [Full Text] [PDF]  

Inga-lill Påhlman, Christer Larsson, Nicole Averét, Odile Bunoust, Samira Boubekeur, Lena Gustafsson, and Michel Rigoulet
Kinetic Regulation of the Mitochondrial Glycerol-3-phosphate Dehydrogenase by the External NADH Dehydrogenase in Saccharomyces cerevisiae
J. Biol. Chem. 2002 277: 27991-27995. First Published on May 24, 2002; 10.1074/jbc.M204079200 [Abstract] [Full Text] [PDF]  

Ana Rute Neves, Rita Ventura, Nahla Mansour, Claire Shearman, Michael J. Gasson, Christopher Maycock, Ana Ramos, and Helena Santos
Is the Glycolytic Flux in Lactococcus lactis Primarily Controlled by the Redox Charge? KINETICS OF NAD+ AND NADH POOLS DETERMINED IN VIVO BY 13C NMR
J. Biol. Chem. 2002 277: 28088-28098. First Published on May 13, 2002; 10.1074/jbc.M202573200 [Abstract] [Full Text] [PDF] Supplemental Data  

Glycobiology and Extracellular Matrices:

Paul C. Billings, J. Charles Whitbeck, Christopher S. Adams, William R. Abrams, Arthur J. Cohen, Beatrice N. Engelsberg, Pamela S. Howard, and Joel Rosenbloom
The Transforming Growth Factor-beta -inducible Matrix Protein beta ig-h3 Interacts with Fibronectin
J. Biol. Chem. 2002 277: 28003-28009. First Published on May 28, 2002; 10.1074/jbc.M106837200 [Abstract] [Full Text] [PDF]  

Geetha L. Poongodi, Nimmagadda Suresh, Subash C. B. Gopinath, Tschining Chang, Sadako Inoue, and Yasuo Inoue
Dynamic Change of Neural Cell Adhesion Molecule Polysialylation on Human Neuroblastoma (IMR-32) and Rat Pheochromocytoma (PC-12) Cells during Growth and Differentiation
J. Biol. Chem. 2002 277: 28200-28211. First Published on May 21, 2002; 10.1074/jbc.M202731200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Jens-Michael Schröder, Robert Häsler, Jörg Grabowsky, Barbara Kahlke, and Anthony I. Mallet
Identification of Diacylated Ureas as a Novel Family of Fungus-specific Leukocyte-activating Pathogen-associated Molecules
J. Biol. Chem. 2002 277: 27887-27895. First Published on May 22, 2002; 10.1074/jbc.M202998200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Joel M. Walker, Ruslan Tsivkovskii, and Svetlana Lutsenko
Metallochaperone Atox1 Transfers Copper to the NH2-terminal Domain of the Wilson's Disease Protein and Regulates Its Catalytic Activity
J. Biol. Chem. 2002 277: 27953-27959. First Published on May 23, 2002; 10.1074/jbc.M203845200 [Abstract] [Full Text] [PDF]  

Nicolai Sidenius, Annapaola Andolfo, Riccardo Fesce, and Francesco Blasi
Urokinase Regulates Vitronectin Binding by Controlling Urokinase Receptor Oligomerization
J. Biol. Chem. 2002 277: 27982-27990. First Published on May 28, 2002; 10.1074/jbc.M111736200 [Abstract] [Full Text] [PDF]  

Nam Soo Joo, Yamil Saenz, Mauri E. Krouse, and Jeffrey J. Wine
Mucus Secretion from Single Submucosal Glands of Pig. STIMULATION BY CARBACHOL AND VASOACTIVE INTESTINAL PEPTIDE
J. Biol. Chem. 2002 277: 28167-28175. First Published on May 13, 2002; 10.1074/jbc.M202712200 [Abstract] [Full Text] [PDF]  

Marion Buyse, Shanthi V. Sitaraman, Xia Liu, Andre Bado, and Didier Merlin
Luminal Leptin Enhances CD147/MCT-1-mediated Uptake of Butyrate in the Human Intestinal Cell Line Caco2-BBE
J. Biol. Chem. 2002 277: 28182-28190. First Published on May 28, 2002; 10.1074/jbc.M203281200 [Abstract] [Full Text] [PDF]  

Juan M. Falcón-Pérez, Marta Starcevic, Rashi Gautam, and Esteban C. Dell'Angelica
BLOC-1, a Novel Complex Containing the Pallidin and Muted Proteins Involved in the Biogenesis of Melanosomes and Platelet-dense Granules
J. Biol. Chem. 2002 277: 28191-28199. First Published on May 17, 2002; 10.1074/jbc.M204011200 [Abstract] [Full Text] [PDF]  

Yankun Li, Lih-Shen Chin, Allan I. Levey, and Lian Li
Huntingtin-associated Protein 1 Interacts with Hepatocyte Growth Factor-regulated Tyrosine Kinase Substrate and Functions in Endosomal Trafficking
J. Biol. Chem. 2002 277: 28212-28221. First Published on May 20, 2002; 10.1074/jbc.M111612200 [Abstract] [Full Text] [PDF]  

Suzie J. Scales, Boris A. Hesser, Esteban S. Masuda, and Richard H. Scheller
Amisyn, a Novel Syntaxin-binding Protein That May Regulate SNARE Complex Assembly
J. Biol. Chem. 2002 277: 28271-28279. First Published on May 24, 2002; 10.1074/jbc.M204929200 [Abstract] [Full Text] [PDF]  

Larry R. Jones, Razvan L. Cornea, and Zhenhui Chen
Close Proximity between Residue 30 of Phospholamban and Cysteine 318 of the Cardiac Ca2+ Pump Revealed by Intermolecular Thiol Cross-linking
J. Biol. Chem. 2002 277: 28319-28329. First Published on May 15, 2002; 10.1074/jbc.M204085200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Sebastien Arico, Sophie Pattingre, Chantal Bauvy, Pierre Gane, Alain Barbat, Patrice Codogno, and Eric Ogier-Denis
Celecoxib Induces Apoptosis by Inhibiting 3-Phosphoinositide-dependent Protein Kinase-1 Activity in the Human Colon Cancer HT-29 Cell Line
J. Biol. Chem. 2002 277: 27613-27621. First Published on May 8, 2002; 10.1074/jbc.M201119200 [Abstract] [Full Text] [PDF]  

Andrew P. Gilmore, Anthony J. Valentijn, Pengbo Wang, Ann M. Ranger, Nigel Bundred, Michael J. O'Hare, Alan Wakeling, Stanley J. Korsmeyer, and Charles H. Streuli
Activation of BAD by Therapeutic Inhibition of Epidermal Growth Factor Receptor and Transactivation by Insulin-like Growth Factor Receptor
J. Biol. Chem. 2002 277: 27643-27650. First Published on May 13, 2002; 10.1074/jbc.M108863200 [Abstract] [Full Text] [PDF]  

Kuniyuki Okada, Paul C. Moe, and Paul Blount
Functional Design of Bacterial Mechanosensitive Channels. COMPARISONS AND CONTRASTS ILLUMINATED BY RANDOM MUTAGENESIS
J. Biol. Chem. 2002 277: 27682-27688. First Published on May 15, 2002; 10.1074/jbc.M202497200 [Abstract] [Full Text] [PDF]  

Ryan T. Terry-Lorenzo, Leigh C. Carmody, James W. Voltz, John H. Connor, Shi Li, F. Donelson Smith, Sharon L. Milgram, Roger J. Colbran, and Shirish Shenolikar
The Neuronal Actin-binding Proteins, Neurabin I and Neurabin II, Recruit Specific Isoforms of Protein Phosphatase-1 Catalytic Subunits
J. Biol. Chem. 2002 277: 27716-27724. First Published on May 16, 2002; 10.1074/jbc.M203365200 [Abstract] [Full Text] [PDF]  

Hana Cho, Ji-Young Hwang, Daesoo Kim, Hee-Sup Shin, Yangmi Kim, Yung E. Earm, and Won-Kyung Ho
Acetylcholine-induced Phosphatidylinositol 4,5-Bisphosphate Depletion Does Not Cause Short-term Desensitization of G Protein-gated Inwardly Rectifying K+ Current in Mouse Atrial Myocytes
J. Biol. Chem. 2002 277: 27742-27747. First Published on May 17, 2002; 10.1074/jbc.M203660200 [Abstract] [Full Text] [PDF]  

Manabu Kawada, Tohru Masuda, Masaaki Ishizuka, and Tomio Takeuchi
15-Deoxyspergualin Inhibits Akt Kinase Activation and Phosphatidylcholine Synthesis
J. Biol. Chem. 2002 277: 27765-27771. First Published on May 20, 2002; 10.1074/jbc.M200318200 [Abstract] [Full Text] [PDF]  

James Jianping Wu and Guido Guidotti
Construction and Characterization of a Monomeric Insulin Receptor
J. Biol. Chem. 2002 277: 27809-27817. First Published on May 22, 2002; 10.1074/jbc.M200367200 [Abstract] [Full Text] [PDF]  

Mark T. Gladwin, Xunde Wang, Christopher D. Reiter, Benjamin K. Yang, Esther X. Vivas, Celia Bonaventura, and Alan N. Schechter
S-Nitrosohemoglobin Is Unstable in the Reductive Erythrocyte Environment and Lacks O2/NO-linked Allosteric Function
J. Biol. Chem. 2002 277: 27818-27828. First Published on May 21, 2002; 10.1074/jbc.M203236200 [Abstract] [Full Text] [PDF]  

Jose M. Lizcano, Maria Deak, Nick Morrice, Agnieszka Kieloch, C. James Hastie, Liying Dong, Mike Schutkowski, Ulf Reimer, and Dario R. Alessi
Molecular Basis for the Substrate Specificity of NIMA-related Kinase-6 (NEK6). EVIDENCE THAT NEK6 DOES NOT PHOSPHORYLATE THE HYDROPHOBIC MOTIF OF RIBOSOMAL S6 PROTEIN KINASE AND SERUM- AND GLUCOCORTICOID-INDUCED PROTEIN KINASE IN VIVO
J. Biol. Chem. 2002 277: 27839-27849. First Published on May 22, 2002; 10.1074/jbc.M202042200 [Abstract] [Full Text] [PDF]  

Francesca Spinella, Laura Rosanò, Valeriana Di Castro, Pier Giorgio Natali, and Anna Bagnato
Endothelin-1 Induces Vascular Endothelial Growth Factor by Increasing Hypoxia-inducible Factor-1alpha in Ovarian Carcinoma Cells
J. Biol. Chem. 2002 277: 27850-27855. First Published on May 22, 2002; 10.1074/jbc.M202421200 [Abstract] [Full Text] [PDF]  

Robert Z. Orlowski, George W. Small, and Yue Y. Shi
Evidence That Inhibition of p44/42 Mitogen-activated Protein Kinase Signaling Is a Factor in Proteasome Inhibitor-mediated Apoptosis
J. Biol. Chem. 2002 277: 27864-27871. First Published on May 22, 2002; 10.1074/jbc.M201519200 [Abstract] [Full Text] [PDF]  

Young-Mi Kim, Sewook Hwang, Young-Myoeng Kim, Bo-Jeong Pyun, Tae-Yoon Kim, Seung-Taek Lee, Yong Song Gho, and Young-Guen Kwon
Endostatin Blocks Vascular Endothelial Growth Factor-mediated Signaling via Direct Interaction with KDR/Flk-1
J. Biol. Chem. 2002 277: 27872-27879. First Published on May 23, 2002; 10.1074/jbc.M202771200 [Abstract] [Full Text] [PDF]  

Thomas Jungas, Iris Motta, Francis Duffieux, Pascale Fanen, Véronique Stoven, and David M. Ojcius
Glutathione Levels and BAX Activation during Apoptosis Due to Oxidative Stress in Cells Expressing Wild-type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator
J. Biol. Chem. 2002 277: 27912-27918. First Published on May 22, 2002; 10.1074/jbc.M110288200 [Abstract] [Full Text] [PDF]  

Minou Adib-Conquy and Jean-Marc Cavaillon
Gamma Interferon and Granulocyte/Monocyte Colony-stimulating Factor Prevent Endotoxin Tolerance in Human Monocytes by Promoting Interleukin-1 Receptor-associated Kinase Expression and Its Association to MyD88 and Not by Modulating TLR4 Expression
J. Biol. Chem. 2002 277: 27927-27934. First Published on May 24, 2002; 10.1074/jbc.M200705200 [Abstract] [Full Text] [PDF]  

Mark M. W. Chong, Helen E. Thomas, and Thomas W. H. Kay
Suppressor of Cytokine Signaling-1 Regulates the Sensitivity of Pancreatic beta Cells to Tumor Necrosis Factor
J. Biol. Chem. 2002 277: 27945-27952. First Published on May 24, 2002; 10.1074/jbc.M110214200 [Abstract] [Full Text] [PDF]  

Caroline Treins, Sophie Giorgetti-Peraldi, Joseph Murdaca, Gregg L. Semenza, and Emmanuel Van Obberghen
Insulin Stimulates Hypoxia-inducible Factor 1 through a Phosphatidylinositol 3-Kinase/Target of Rapamycin-dependent Signaling Pathway
J. Biol. Chem. 2002 277: 27975-27981. First Published on May 24, 2002; 10.1074/jbc.M204152200 [Abstract] [Full Text] [PDF]  

Vidya Mamidipudi, Xiaoxia Li, and Marie W. Wooten
Identification of Interleukin 1 Receptor-associated Kinase as a Conserved Component in the p75-Neurotrophin Receptor Activation of Nuclear Factor-kappa B
J. Biol. Chem. 2002 277: 28010-28018. First Published on May 28, 2002; 10.1074/jbc.M109730200 [Abstract] [Full Text] [PDF]  

You Cheng Xu, Ru Feng Wu, Ying Gu, Yih-Sheng Yang, Meng-Chun Yang, Fiemu E. Nwariaku, and Lance S. Terada
Involvement of TRAF4 in Oxidative Activation of c-Jun N-terminal Kinase
J. Biol. Chem. 2002 277: 28051-28057. First Published on May 22, 2002; 10.1074/jbc.M202665200 [Abstract] [Full Text] [PDF]  

Carlos Guillén, Pilar Martínez, Arancha R. de Gortázar, María Eugenia Martínez, and Pedro Esbrit
Both N- and C-terminal Domains of Parathyroid Hormone-related Protein Increase Interleukin-6 by Nuclear Factor-kappa B Activation in Osteoblastic Cells
J. Biol. Chem. 2002 277: 28109-28117. First Published on May 8, 2002; 10.1074/jbc.M111013200 [Abstract] [Full Text] [PDF]  

Ahmed A. Samatar, Luquan Wang, Asra Mirza, Sandra Koseoglu, Suxing Liu, and Chandra C. Kumar
Transforming Growth Factor-beta 2 Is a Transcriptional Target for Akt/Protein Kinase B via Forkhead Transcription Factor
J. Biol. Chem. 2002 277: 28118-28126. First Published on May 14, 2002; 10.1074/jbc.M203686200 [Abstract] [Full Text] [PDF]  

Xiongwen Zhang, Lili Shu, Hajime Hosoi, K. Gopal Murti, and Peter J. Houghton
Predominant Nuclear Localization of Mammalian Target of Rapamycin in Normal and Malignant Cells in Culture
J. Biol. Chem. 2002 277: 28127-28134. First Published on May 8, 2002; 10.1074/jbc.M202625200 [Abstract] [Full Text] [PDF]  

Chang-Cheng Zhu, Laurie B. Cook, and Patricia M. Hinkle
Dimerization and Phosphorylation of Thyrotropin-releasing Hormone Receptors Are Modulated by Agonist Stimulation
J. Biol. Chem. 2002 277: 28228-28237. First Published on May 22, 2002; 10.1074/jbc.M204221200 [Abstract] [Full Text] [PDF]  

Margaret Porter Scott, Francesca Zappacosta, Eun Young Kim, Roland S. Annan, and W. Todd Miller
Identification of Novel SH3 Domain Ligands for the Src Family Kinase Hck. WISKOTT-ALDRICH SYNDROME PROTEIN (WASP), WASP-INTERACTING PROTEIN (WIP), AND ELMO1
J. Biol. Chem. 2002 277: 28238-28246. First Published on May 23, 2002; 10.1074/jbc.M202783200 [Abstract] [Full Text] [PDF]  

Susumu Tanimura, Kayo Nomura, Kei-ichi Ozaki, Masafumi Tsujimoto, Takahito Kondo, and Michiaki Kohno
Prolonged Nuclear Retention of Activated Extracellular Signal-regulated Kinase 1/2 Is Required for Hepatocyte Growth Factor-induced Cell Motility
J. Biol. Chem. 2002 277: 28256-28264. First Published on May 24, 2002; 10.1074/jbc.M202866200 [Abstract] [Full Text] [PDF]  

George S. Baillie, Elaine Huston, Grant Scotland, Matt Hodgkin, Irene Gall, Alex H. Peden, Carolynn MacKenzie, Emma S. Houslay, Richard Currie, Trevor R. Pettitt, Adrian R. Walmsley, Michael J. O. Wakelam, Jim Warwicker, and Miles D. Houslay
TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid
J. Biol. Chem. 2002 277: 28298-28309. First Published on May 6, 2002; 10.1074/jbc.M108353200 [Abstract] [Full Text] [PDF]  

Alan Berezov, Jinqiu Chen, Qingdu Liu, Hong-Tao Zhang, Mark I. Greene, and Ramachandran Murali
Disabling Receptor Ensembles with Rationally Designed Interface Peptidomimetics
J. Biol. Chem. 2002 277: 28330-28339. First Published on May 14, 2002; 10.1074/jbc.M202880200 [Abstract] [Full Text] [PDF]  

Deming Gong, Zhizhong Gong, Yan Guo, Xiuyin Chen, and Jian-Kang Zhu
Biochemical and Functional Characterization of PKS11, a Novel Arabidopsis Protein Kinase
J. Biol. Chem. 2002 277: 28340-28350. First Published on May 23, 2002; 10.1074/jbc.M107719200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Hiroshi Kubota, Robert W. Storms, and Lola M. Reid
Variant Forms of alpha -Fetoprotein Transcripts Expressed in Human Hematopoietic Progenitors. IMPLICATIONS FOR THEIR DEVELOPMENTAL POTENTIAL TOWARDS ENDODERM
J. Biol. Chem. 2002 277: 27629-27635. First Published on May 10, 2002; 10.1074/jbc.M202117200 [Abstract] [Full Text] [PDF]  

Fabio D'Atri, Fabio Nadalutti, and Sandra Citi
Evidence for a Functional Interaction between Cingulin and ZO-1 in Cultured Cells
J. Biol. Chem. 2002 277: 27757-27764. First Published on May 21, 2002; 10.1074/jbc.M203717200 [Abstract] [Full Text] [PDF]  

Toshikichi Hayashi, Toshio Kaneda, Yoshiaki Toyama, Masayoshi Kumegawa, and Yoshiyuki Hakeda
Regulation of Receptor Activator of NF-kappa B Ligand-induced Osteoclastogenesis by Endogenous Interferon-beta (INF-beta ) and Suppressors of Cytokine Signaling (SOCS). THE POSSIBLE COUNTERACTING ROLE OF SOCSs IN IFN-beta -INHIBITED OSTEOCLAST FORMATION
J. Biol. Chem. 2002 277: 27880-27886. First Published on May 22, 2002; 10.1074/jbc.M203836200 [Abstract] [Full Text] [PDF]  

Steven M. Claypool, Bonny L. Dickinson, Masaru Yoshida, Wayne I. Lencer, and Richard S. Blumberg
Functional Reconstitution of Human FcRn in Madin-Darby Canine Kidney Cells Requires Co-expressed Human beta 2-Microglobulin
J. Biol. Chem. 2002 277: 28038-28050. First Published on May 22, 2002; 10.1074/jbc.M202367200 [Abstract] [Full Text] [PDF]  

Tetsuo Yamashita, Morichika Konishi, Ayumi Miyake, Ken-ichi Inui, and Nobuyuki Itoh
Fibroblast Growth Factor (FGF)-23 Inhibits Renal Phosphate Reabsorption by Activation of the Mitogen-activated Protein Kinase Pathway
J. Biol. Chem. 2002 277: 28265-28270. First Published on May 24, 2002; 10.1074/jbc.M202527200 [Abstract] [Full Text] [PDF]  

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