JBC -- Table of Contents (Nov 8 2002, 277, (45))

HOME

HELP

FEEDBACK

SUBSCRIPTIONS

Accelerated Publications:

Graham M. T. Cheetham, Ronald M. A. Knegtel, Joyce T. Coll, Suzanne B. Renwick, Lora Swenson, Peter Weber, Judith A. Lippke, and Douglas A. Austen: Crystal Structure of Aurora-2, an Oncogenic Serine/Threonine Kinase
J. Biol. Chem. 2002 277: 42419-42422. First Published on September 16, 2002; doi:10.1074/jbc.C200426200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Yong-Dong Wang, Jaroslaw Dziegielewski, Aileen Y. Chang, Peter B. Dervan, and Terry A. Beerman: Cell-free and Cellular Activities of a DNA Sequence Selective Hairpin Polyamide-CBI Conjugate
J. Biol. Chem. 2002 277: 42431-42437. First Published on August 23, 2002; doi:10.1074/jbc.M207179200 [Abstract] [Full Text] [PDF]

Zhiying You, Yukio Ishimi, Hisao Masai, and Fumio Hanaoka: Roles of Mcm7 and Mcm4 Subunits in the DNA Helicase Activity of the Mouse Mcm4/6/7 Complex
J. Biol. Chem. 2002 277: 42471-42479. First Published on August 30, 2002; doi:10.1074/jbc.M205769200 [Abstract] [Full Text] [PDF]

Katalin Szászi, Anders Paulsen, Elöd Z. Szabó, Masayuki Numata, Sergio Grinstein, and John Orlowski: Clathrin-mediated Endocytosis and Recycling of the Neuron-specific Na⁺/H⁺ Exchanger NHE5 Isoform. REGULATION BY PHOSPHATIDYLINOSITOL 3'-KINASE AND THE ACTIN CYTOSKELETON
J. Biol. Chem. 2002 277: 42623-42632. First Published on August 29, 2002; doi:10.1074/jbc.M206629200 [Abstract] [Full Text] [PDF]

Devon R. Byrd, Juliana K. Sampson, Heather M. Ragonese, and Steven W. Matson: Structure-Function Analysis of Escherichia coli DNA Helicase I Reveals Non-overlapping Transesterase and Helicase Domains
J. Biol. Chem. 2002 277: 42645-42653. First Published on August 30, 2002; doi:10.1074/jbc.M205984200 [Abstract] [Full Text] [PDF]

Stefan Sigurdsson, Stephen Van Komen, Galina Petukhova, and Patrick Sung: Homologous DNA Pairing by Human Recombination Factors Rad51 and Rad54
J. Biol. Chem. 2002 277: 42790-42794. First Published on August 29, 2002; doi:10.1074/jbc.M208004200 [Abstract] [Full Text] [PDF]

Yoshinori Takei, Magdalena Assenberg, Gozoh Tsujimoto, and Ronald Laskey: The MCM3 Acetylase MCM3AP Inhibits Initiation, but Not Elongation, of DNA Replication via Interaction with MCM3
J. Biol. Chem. 2002 277: 43121-43125. First Published on September 10, 2002; doi:10.1074/jbc.C200442200 [Abstract] [Full Text] [PDF]

Valérie Goldschmidt, Mickaël Rigourd, Chantal Ehresmann, Stuart F. J. Le Grice, Bernard Ehresmann, and Roland Marquet: Direct and Indirect Contributions of RNA Secondary Structure Elements to the Initiation of HIV-1 Reverse Transcription
J. Biol. Chem. 2002 277: 43233-43242. First Published on August 22, 2002; doi:10.1074/jbc.M205295200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Lynne D. Vales and Erika M. Friedl: Binding of C/EBP and RBP (CBF1) to Overlapping Sites Regulates Interleukin-6 Gene Expression
J. Biol. Chem. 2002 277: 42438-42446. First Published on August 27, 2002; doi:10.1074/jbc.M207363200 [Abstract] [Full Text] [PDF]

Alexander V. Medvedev, Jacques Robidoux, Xu Bai, Wenhong Cao, Lisa M. Floering, Kiefer W. Daniel, and Sheila Collins: Regulation of the Uncoupling Protein-2 Gene in INS-1 $beta$ -Cells by Oleic Acid
J. Biol. Chem. 2002 277: 42639-42644. First Published on August 29, 2002; doi:10.1074/jbc.M208645200 [Abstract] [Full Text] [PDF]

John S. Welch, Laure Escoubet-Lozach, David B. Sykes, Kate Liddiard, David R. Greaves, and Christopher K. Glass: T_H2 Cytokines and Allergic Challenge Induce Ym1 Expression in Macrophages by a STAT6-dependent Mechanism
J. Biol. Chem. 2002 277: 42821-42829. First Published on September 4, 2002; doi:10.1074/jbc.M205873200 [Abstract] [Full Text] [PDF]

Rémy Castellano, Carine Van Lint, Valentine Péri, Emmanuelle Veithen, Yannis Morel, Régis Costello, Daniel Olive, and Yves Collette: Mechanisms Regulating Expression of the Tumor Necrosis Factor-related light Gene. ROLE OF CALCIUM-SIGNALING PATHWAY IN THE TRANSCRIPTIONAL CONTROL
J. Biol. Chem. 2002 277: 42841-42851. First Published on September 4, 2002; doi:10.1074/jbc.M207689200 [Abstract] [Full Text] [PDF]

Qianben Wang, Dipali Sharma, Yunsheng Ren, and Joseph D. Fondell: A Coregulatory Role for the TRAP-Mediator Complex in Androgen Receptor-mediated Gene Expression
J. Biol. Chem. 2002 277: 42852-42858. First Published on September 5, 2002; doi:10.1074/jbc.M206061200 [Abstract] [Full Text] [PDF]

Alexandra Grosfeld, Jocelyne André, Sylvie Hauguel-de Mouzon, Edurne Berra, Jacques Pouysségur, and Michèle Guerre-Millo: Hypoxia-inducible Factor 1 Transactivates the Human Leptin Gene Promoter
J. Biol. Chem. 2002 277: 42953-42957. First Published on September 4, 2002; doi:10.1074/jbc.M206775200 [Abstract] [Full Text] [PDF]

Marie-Christine Gerbod-Giannone, Antonio del Castillo-Olivares, Sabina Janciauskiene, Gregorio Gil, and Phillip B Hylemon: Suppression of Cholesterol 7 $alpha$ -Hydroxylase Transcription and Bile Acid Synthesis by an $alpha$ ₁-Antitrypsin Peptide via Interaction with $alpha$ ₁-Fetoprotein Transcription Factor
J. Biol. Chem. 2002 277: 42973-42980. First Published on September 9, 2002; doi:10.1074/jbc.M205089200 [Abstract] [Full Text] [PDF]

Guadalupe Nogués, Sebastián Kadener, Paula Cramer, David Bentley, and Alberto R. Kornblihtt: Transcriptional Activators Differ in Their Abilities to Control Alternative Splicing
J. Biol. Chem. 2002 277: 43110-43114. First Published on September 6, 2002; doi:10.1074/jbc.M208418200 [Abstract] [Full Text] [PDF]

Natalie K. Goto, Tsaffrir Zor, Maria Martinez-Yamout, H. Jane Dyson, and Peter E. Wright: Cooperativity in Transcription Factor Binding to the Coactivator CREB-binding Protein (CBP). THE MIXED LINEAGE LEUKEMIA PROTEIN (MLL) ACTIVATION DOMAIN BINDS TO AN ALLOSTERIC SITE ON THE KIX DOMAIN
J. Biol. Chem. 2002 277: 43168-43174. First Published on August 29, 2002; doi:10.1074/jbc.M207660200 [Abstract] [Full Text] [PDF]

María Isabel Tussié-Luna, Bertha Michel, Shweta Hakre, and Ananda L. Roy: The SUMO Ubiquitin-Protein Isopeptide Ligase Family Member Miz1/PIASx $beta$ /Siz2 Is a Transcriptional Cofactor for TFII-I
J. Biol. Chem. 2002 277: 43185-43193. First Published on August 21, 2002; doi:10.1074/jbc.M207635200 [Abstract] [Full Text] [PDF]

Xiaocheng Dong, Kalpana Ghoshal, Sarmila Majumder, Satya P. Yadav, and Samson T. Jacob: Mitochondrial Transcription Factor A and Its Downstream Targets Are Up-regulated in a Rat Hepatoma
J. Biol. Chem. 2002 277: 43309-43318. First Published on August 26, 2002; doi:10.1074/jbc.M206958200 [Abstract] [Full Text] [PDF]

Andrei O. Zalensky, Joseph S. Siino, Arunas A. Gineitis, Irina A. Zalenskaya, Nikolai V. Tomilin, Peter Yau, and E. Morton Bradbury: Human Testis/Sperm-specific Histone H2B (hTSH2B). MOLECULAR CLONING AND CHARACTERIZATION
J. Biol. Chem. 2002 277: 43474-43480. First Published on September 3, 2002; doi:10.1074/jbc.M206065200 [Abstract] [Full Text] [PDF]

Jian Du, Monika J. Stankiewicz, Yang Liu, Qing Xi, Jonathan E. Schmitz, Julie A. Lekstrom-Himes, and Steven J. Ackerman: Novel Combinatorial Interactions of GATA-1, PU.1, and C/EBP $epsilon$ Isoforms Regulate Transcription of the Gene Encoding Eosinophil Granule Major Basic Protein
J. Biol. Chem. 2002 277: 43481-43494. First Published on August 28, 2002; doi:10.1074/jbc.M204777200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Ronit Erlitzki, Joanne C. Long, and Elizabeth C. Theil: Multiple, Conserved Iron-responsive Elements in the 3'-Untranslated Region of Transferrin Receptor mRNA Enhance Binding of Iron Regulatory Protein 2
J. Biol. Chem. 2002 277: 42579-42587. First Published on August 27, 2002; doi:10.1074/jbc.M207918200 [Abstract] [Full Text] [PDF]

Weiwen Ge, Junhua Wu, Jinbin Zhai, Zhenying Nie, Hong Lin, William W. Schlaepfer, and Rafaela Cañete-Soler: Binding of p190RhoGEF to a Destabilizing Element on the Light Neurofilament mRNA Is Competed by BC1 RNA
J. Biol. Chem. 2002 277: 42701-42705. First Published on September 4, 2002; doi:10.1074/jbc.M206635200 [Abstract] [Full Text] [PDF]

Barbara J. Natalizio, Luis C. Muñiz, George K. Arhin, Jeffrey Wilusz, and Carol S. Lutz: Upstream Elements Present in the 3'-Untranslated Region of Collagen Genes Influence the Processing Efficiency of Overlapping Polyadenylation Signals
J. Biol. Chem. 2002 277: 42733-42740. First Published on August 27, 2002; doi:10.1074/jbc.M208070200 [Abstract] [Full Text] [PDF]

Ian J. Orozco, Steven J. Kim, and Harold G. Martinson: The Poly(A) Signal, without the Assistance of Any Downstream Element, Directs RNA Polymerase II to Pause in Vivo and Then to Release Stochastically from the Template
J. Biol. Chem. 2002 277: 42899-42911. First Published on August 23, 2002; doi:10.1074/jbc.M207415200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Ziyin Li and Ching C. Wang: Functional Characterization of the 11 Non-ATPase Subunit Proteins in the Trypanosome 19 S Proteasomal Regulatory Complex
J. Biol. Chem. 2002 277: 42686-42693. First Published on September 3, 2002; doi:10.1074/jbc.M207183200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anna Rita Bellu, Florian A. Salomons, Jan A. K. W. Kiel, Marten Veenhuis, and Ida J. van der Klei: Removal of Pex3p Is an Important Initial Stage in Selective Peroxisome Degradation in Hansenula polymorpha
J. Biol. Chem. 2002 277: 42875-42880. First Published on September 6, 2002; doi:10.1074/jbc.M205437200 [Abstract] [Full Text] [PDF]

Zsuzsa Bebok, Karoly Varga, James K. Hicks, Charles J. Venglarik, Timea Kovacs, Lan Chen, Karin M. Hardiman, James F. Collawn, Eric J. Sorscher, and Sadis Matalon: Reactive Oxygen Nitrogen Species Decrease Cystic Fibrosis Transmembrane Conductance Regulator Expression and cAMP-mediated Cl Secretion in Airway Epithelia
J. Biol. Chem. 2002 277: 43041-43049. First Published on August 22, 2002; doi:10.1074/jbc.M203154200 [Abstract] [Full Text] [PDF]

Hideyuki Suzuki and Hidehiko Kumagai: Autocatalytic Processing of $gamma$ -Glutamyltranspeptidase
J. Biol. Chem. 2002 277: 43536-43543. First Published on August 31, 2002; doi:10.1074/jbc.M207680200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Giulia Fontemaggi, Itai Kela, Ninette Amariglio, Gideon Rechavi, Janakiraman Krishnamurthy, Sabrina Strano, Ada Sacchi, David Givol, and Giovanni Blandino: Identification of Direct p73 Target Genes Combining DNA Microarray and Chromatin Immunoprecipitation Analyses
J. Biol. Chem. 2002 277: 43359-43368. First Published on September 3, 2002; doi:10.1074/jbc.M205573200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Carlos Velazquez, Ilan Vidavsky, Koen van der Drift, Michael L. Gross, and Emil R. Unanue: Chemical Identification of a Low Abundance Lysozyme Peptide Family Bound to I-A^k Histocompatibility Molecules
J. Biol. Chem. 2002 277: 42514-42522. First Published on June 7, 2002; doi:10.1074/jbc.M202316200 [Abstract] [Full Text] [PDF]

Gen Kobayashi, Takashi Nakamura, Hitoshi Ohmachi, Ariki Matsuoka, Takehiko Ochiai, and Keiji Shikama: Yeast Flavohemoglobin from Candida norvegensis. ITS STRUCTURAL, SPECTRAL, AND STABILITY PROPERTIES
J. Biol. Chem. 2002 277: 42540-42548. First Published on August 20, 2002; doi:10.1074/jbc.M206529200 [Abstract] [Full Text] [PDF]

Ranveig Braathen, Vigdis Sørensen, Per Brandtzaeg, Inger Sandlie, and Finn-Eirik Johansen: The Carboxyl-terminal Domains of IgA and IgM Direct Isotype-specific Polymerization and Interaction with the Polymeric Immunoglobulin Receptor
J. Biol. Chem. 2002 277: 42755-42762. First Published on September 3, 2002; doi:10.1074/jbc.M205502200 [Abstract] [Full Text] [PDF]

Hilal A. Lashuel, Dean M. Hartley, David Balakhaneh, Aneel Aggarwal, Saul Teichberg, and David J. E. Callaway: New Class of Inhibitors of Amyloid- $beta$ Fibril Formation. IMPLICATIONS FOR THE MECHANISM OF PATHOGENESIS IN ALZHEIMER'S DISEASE
J. Biol. Chem. 2002 277: 42881-42890. First Published on August 6, 2002; doi:10.1074/jbc.M206593200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Luke A. Miles, Catherine Y. Dy, Jake Nielsen, Kevin J. Barnham, Mark G. Hinds, Baldomero M. Olivera, Grzegorz Bulaj, and Raymond S. Norton: Structure of a Novel P-superfamily Spasmodic Conotoxin Reveals an Inhibitory Cystine Knot Motif
J. Biol. Chem. 2002 277: 43033-43040. First Published on August 21, 2002; doi:10.1074/jbc.M206690200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Björn Philipps and Rudi Glockshuber: Randomization of the Entire Active-site Helix $alpha$ 1 of the Thiol-disulfide Oxidoreductase DsbA from Escherichia coli
J. Biol. Chem. 2002 277: 43050-43057. First Published on August 21, 2002; doi:10.1074/jbc.M207638200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ville O. Paavilainen, Michael C. Merckel, Sandra Falck, Pauli J. Ojala, Ehmke Pohl, Matthias Wilmanns, and Pekka Lappalainen: Structural Conservation between the Actin Monomer-binding Sites of Twinfilin and Actin-depolymerizing Factor (ADF)/Cofilin
J. Biol. Chem. 2002 277: 43089-43095. First Published on August 30, 2002; doi:10.1074/jbc.M208225200 [Abstract] [Full Text] [PDF]

Yuliya V. Korolkova, Eduard V. Bocharov, Kamilla Angelo, Innokenty V. Maslennikov, Olga V. Grinenko, Aleksey V. Lipkin, Elena D. Nosyreva, Kirill A. Pluzhnikov, Søren-Peter Olesen, Alexander S. Arseniev, and Eugene V. Grishin: New Binding Site on Common Molecular Scaffold Provides HERG Channel Specificity of Scorpion Toxin BeKm-1
J. Biol. Chem. 2002 277: 43104-43109. First Published on July 31, 2002; doi:10.1074/jbc.M204083200 [Abstract] [Full Text] [PDF] [Supplemental Data]

A. B. Madhankumar, Akiva Mintz, and Waldemar Debinski: Alanine-scanning Mutagenesis of $alpha$ -Helix D Segment of Interleukin-13 Reveals New Functionally Important Residues of the Cytokine
J. Biol. Chem. 2002 277: 43194-43205. First Published on August 19, 2002; doi:10.1074/jbc.M205047200 [Abstract] [Full Text] [PDF]

Kaiyu Ma, Dmitri Temiakov, Manli Jiang, Michael Anikin, and William T. McAllister: Major Conformational Changes Occur during the Transition from an Initiation Complex to an Elongation Complex by T7 RNA Polymerase
J. Biol. Chem. 2002 277: 43206-43215. First Published on August 16, 2002; doi:10.1074/jbc.M206658200 [Abstract] [Full Text] [PDF]

Lars Tjernberg, Waltteri Hosia, Niklas Bark, Johan Thyberg, and Jan Johansson: Charge Attraction and $beta$ Propensity Are Necessary for Amyloid Fibril Formation from Tetrapeptides
J. Biol. Chem. 2002 277: 43243-43246. First Published on September 4, 2002; doi:10.1074/jbc.M205570200 [Abstract] [Full Text] [PDF]

José Manuel Andreu, María Angela Oliva, and Octavio Monasterio: Reversible Unfolding of FtsZ Cell Division Proteins from Archaea and Bacteria. COMPARISON WITH EUKARYOTIC TUBULIN FOLDING AND ASSEMBLY
J. Biol. Chem. 2002 277: 43262-43270. First Published on September 4, 2002; doi:10.1074/jbc.M206723200 [Abstract] [Full Text] [PDF]

Jianxin Shi, Zoran Radi $c'$ , and Palmer Taylor: Inhibitors of Different Structure Induce Distinguishing Conformations in the Omega Loop, Cys⁶⁹-Cys⁹⁶, of Mouse Acetylcholinesterase
J. Biol. Chem. 2002 277: 43301-43308. First Published on August 24, 2002; doi:10.1074/jbc.M204391200 [Abstract] [Full Text] [PDF]

Yves A. Muller, Christoph Heiring, Rolf Misselwitz, Karin Welfle, and Heinz Welfle: The Cystine Knot Promotes Folding and Not Thermodynamic Stability in Vascular Endothelial Growth Factor
J. Biol. Chem. 2002 277: 43410-43416. First Published on August 30, 2002; doi:10.1074/jbc.M206438200 [Abstract] [Full Text] [PDF]

Alexandre Chenal, Philippe Savarin, Philippe Nizard, Florent Guillain, Daniel Gillet, and Vincent Forge: Membrane Protein Insertion Regulated by Bringing Electrostatic and Hydrophobic Interactions into Play. A CASE STUDY WITH THE TRANSLOCATION DOMAIN OF THE DIPHTHERIA TOXIN
J. Biol. Chem. 2002 277: 43425-43432. First Published on August 21, 2002; doi:10.1074/jbc.M204148200 [Abstract] [Full Text] [PDF]

Kathryn L. Kavanagh, Mario Klimacek, Bernd Nidetzky, and David K. Wilson: Crystal Structure of Pseudomonas fluorescens Mannitol 2-Dehydrogenase Binary and Ternary Complexes. SPECIFICITY AND CATALYTIC MECHANISM
J. Biol. Chem. 2002 277: 43433-43442. First Published on August 23, 2002; doi:10.1074/jbc.M206914200 [Abstract] [Full Text] [PDF]

Qing-xin Hua, Ying-Chi Chu, Wenhua Jia, Nelson F. B. Phillips, Run-ying Wang, Panayotis G. Katsoyannis, and Michael A. Weiss: Mechanism of Insulin Chain Combination. ASYMMETRIC ROLES OF A-CHAIN $alpha$ -HELICES IN DISULFIDE PAIRING
J. Biol. Chem. 2002 277: 43443-43453. First Published on August 23, 2002; doi:10.1074/jbc.M206107200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Christopher Ceccarelli, Neil B. Grodsky, Nandana Ariyaratne, Roberta F. Colman, and Brian J. Bahnson: Crystal Structure of Porcine Mitochondrial NADP⁺-dependent Isocitrate Dehydrogenase Complexed with Mn²⁺ and Isocitrate. INSIGHTS INTO THE ENZYME MECHANISM
J. Biol. Chem. 2002 277: 43454-43462. First Published on August 30, 2002; doi:10.1074/jbc.M207306200 [Abstract] [Full Text] [PDF]

Uma Narendra, Lingyang Zhu, Biaoru Li, Jill Wilken, and Michael A. Weiss: Sex-specific Gene Regulation. THE DOUBLESEX DM MOTIF IS A BIPARTITE DNA-BINDING DOMAIN
J. Biol. Chem. 2002 277: 43463-43473. First Published on August 26, 2002; doi:10.1074/jbc.M204616200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

W. David Nes, Julie A. Marshall, Zhonghua Jia, Tahhan T. Jaradat, Zhihong Song, and Pruthvi Jayasimha: Active Site Mapping and Substrate Channeling in the Sterol Methyltransferase Pathway
J. Biol. Chem. 2002 277: 42549-42556. First Published on August 23, 2002; doi:10.1074/jbc.M204223200 [Abstract] [Full Text] [PDF]

Zoltán Szeltner, Dean Rea, Veronika Renner, Vilmos Fülöp, and László Polgár: Electrostatic Effects and Binding Determinants in the Catalysis of Prolyl Oligopeptidase. SITE-SPECIFIC MUTAGENESIS AT THE OXYANION BINDING SITE
J. Biol. Chem. 2002 277: 42613-42622. First Published on August 28, 2002; doi:10.1074/jbc.M208043200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Salem Chouchane, Stefania Girotto, Shengwei Yu, and Richard S. Magliozzo: Identification and Characterization of Tyrosyl Radical Formation in Mycobacterium tuberculosis Catalase-Peroxidase (KatG)
J. Biol. Chem. 2002 277: 42633-42638. First Published on August 29, 2002; doi:10.1074/jbc.M207916200 [Abstract] [Full Text] [PDF]

Donna K. Mahnke-Zizelman and Richard L. Sabina: N-terminal Sequence and Distal Histidine Residues Are Responsible for pH-regulated Cytoplasmic Membrane Binding of Human AMP Deaminase Isoform E
J. Biol. Chem. 2002 277: 42654-42662. First Published on September 3, 2002; doi:10.1074/jbc.M203473200 [Abstract] [Full Text] [PDF]

Ilia G. Denisov, Thomas M. Makris, and Stephen G. Sligar: Formation and Decay of Hydroperoxo-Ferric Heme Complex in Horseradish Peroxidase Studied by Cryoradiolysis
J. Biol. Chem. 2002 277: 42706-42710. First Published on September 4, 2002; doi:10.1074/jbc.M207949200 [Abstract] [Full Text] [PDF]

Sanja Roje, Machhindra T. Janave, Michael J. Ziemak, and Andrew D. Hanson: Cloning and Characterization of Mitochondrial 5-Formyltetrahydrofolate Cycloligase from Higher Plants
J. Biol. Chem. 2002 277: 42748-42754. First Published on August 30, 2002; doi:10.1074/jbc.M205632200 [Abstract] [Full Text] [PDF]

Carl R. Flannery, Weilan Zeng, Chris Corcoran, Lisa A. Collins-Racie, Priya S. Chockalingam, Tracy Hebert, Stewart A. Mackie, Thomas McDonagh, Tara K. Crawford, Kathy N. Tomkinson, Edward R. LaVallie, and Elisabeth A. Morris: Autocatalytic Cleavage of ADAMTS-4 (Aggrecanase-1) Reveals Multiple Glycosaminoglycan-binding Sites
J. Biol. Chem. 2002 277: 42775-42780. First Published on August 28, 2002; doi:10.1074/jbc.M205309200 [Abstract] [Full Text] [PDF]

James L. Thomas, J. Ian Mason, Stacey Brandt, Byron R. Spencer, Jr., and Wendy Norris: Structure/Function Relationships Responsible for the Kinetic Differences between Human Type 1 and Type 2 3 $beta$ -Hydroxysteroid Dehydrogenase and for the Catalysis of the Type 1 Activity
J. Biol. Chem. 2002 277: 42795-42801. First Published on August 29, 2002; doi:10.1074/jbc.M208537200 [Abstract] [Full Text] [PDF]

Nils Hoffmann, Amro A. Amara, Br. Bernd Beermann, Qingsheng Qi, Hans-Jürgen Hinz, and Bernd H. A. Rehm: Biochemical Characterization of the Pseudomonas putida 3-Hydroxyacyl ACP:CoA Transacylase, Which Diverts Intermediates of Fatty Acid de Novo Biosynthesis
J. Biol. Chem. 2002 277: 42926-42936. First Published on August 27, 2002; doi:10.1074/jbc.M207821200 [Abstract] [Full Text] [PDF]

Eric F. Johnson, Wolfgang Hinz, Chloé E. Atreya, Frank Maley, and Karen S. Anderson: Mechanistic Characterization of Toxoplasma gondii Thymidylate Synthase (TS-DHFR)-Dihydrofolate Reductase. EVIDENCE FOR A TS INTERMEDIATE AND TS HALF-SITES REACTIVITY
J. Biol. Chem. 2002 277: 43126-43136. First Published on August 20, 2002; doi:10.1074/jbc.M206523200 [Abstract] [Full Text] [PDF]

Balajee R. Somalinga and Rajendra P. Roy: Volume Exclusion Effect as a Driving Force for Reverse Proteolysis. IMPLICATIONS FOR POLYPEPTIDE ASSEMBLAGE IN A MACROMOLECULAR CROWDED MILIEU
J. Biol. Chem. 2002 277: 43253-43261. First Published on August 30, 2002; doi:10.1074/jbc.M207974200 [Abstract] [Full Text] [PDF]

Jian-Ming Gu, James T. B. Crawley, Gary Ferrell, Fangjiu Zhang, Weihong Li, Naomi L. Esmon, and Charles T. Esmon: Disruption of the Endothelial Cell Protein C Receptor Gene in Mice Causes Placental Thrombosis and Early Embryonic Lethality
J. Biol. Chem. 2002 277: 43335-43343. First Published on September 5, 2002; doi:10.1074/jbc.M207538200 [Abstract] [Full Text] [PDF]

Jenny Sandmark, Stéphane Mann, Andrée Marquet, and Gunter Schneider: Structural Basis for the Inhibition of the Biosynthesis of Biotin by the Antibiotic Amiclenomycin
J. Biol. Chem. 2002 277: 43352-43358. First Published on September 5, 2002; doi:10.1074/jbc.M207239200 [Abstract] [Full Text] [PDF]

Kenneth M. Humphries, Celina Juliano, and Susan S. Taylor: Regulation of cAMP-dependent Protein Kinase Activity by Glutathionylation
J. Biol. Chem. 2002 277: 43505-43511. First Published on August 19, 2002; doi:10.1074/jbc.M207088200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Elsa Wiame, Ghislain Delpierre, François Collard, and Emile Van Schaftingen: Identification of a Pathway for the Utilization of the Amadori Product Fructoselysine in Escherichia coli
J. Biol. Chem. 2002 277: 42523-42529. First Published on July 29, 2002; doi:10.1074/jbc.M200863200 [Abstract] [Full Text] [PDF]

Lisa O'Rourke, Line M. Grønning, Stephen J. Yeaman, and Peter R. Shepherd: Glucose-dependent Regulation of Cholesterol Ester Metabolism in Macrophages by Insulin and Leptin
J. Biol. Chem. 2002 277: 42557-42562. First Published on August 27, 2002; doi:10.1074/jbc.M202151200 [Abstract] [Full Text] [PDF]

Kevin R. Messner and James A. Imlay: Mechanism of Superoxide and Hydrogen Peroxide Formation by Fumarate Reductase, Succinate Dehydrogenase, and Aspartate Oxidase
J. Biol. Chem. 2002 277: 42563-42571. First Published on August 27, 2002; doi:10.1074/jbc.M204958200 [Abstract] [Full Text] [PDF]

Nicolas L. Taylor, David A. Day, and A. Harvey Millar: Environmental Stress Causes Oxidative Damage to Plant Mitochondria Leading to Inhibition of Glycine Decarboxylase
J. Biol. Chem. 2002 277: 42663-42668. First Published on September 3, 2002; doi:10.1074/jbc.M204761200 [Abstract] [Full Text] [PDF]

Hong Xu, Dmitrii Vavilin, and Wim Vermaas: The Presence of Chlorophyll b in Synechocystis sp. PCC 6803 Disturbs Tetrapyrrole Biosynthesis and Enhances Chlorophyll Degradation
J. Biol. Chem. 2002 277: 42726-42732. First Published on August 30, 2002; doi:10.1074/jbc.M205237200 [Abstract] [Full Text] [PDF]

Alicia J. Kowaltowski, Ricardo G. Cosso, Cláudia B. Campos, and Gary Fiskum: Effect of Bcl-2 Overexpression on Mitochondrial Structure and Function
J. Biol. Chem. 2002 277: 42802-42807. First Published on August 30, 2002; doi:10.1074/jbc.M207765200 [Abstract] [Full Text] [PDF]

Shobhitha Ratnam, Kenneth N. Maclean, Rene L. Jacobs, Margaret E. Brosnan, Jan P. Kraus, and John T. Brosnan: Hormonal Regulation of Cystathionine $beta$ -Synthase Expression in Liver
J. Biol. Chem. 2002 277: 42912-42918. First Published on August 26, 2002; doi:10.1074/jbc.M206588200 [Abstract] [Full Text] [PDF]

Alexander V. Ruban, Andy Pascal, Pamela J. Lee, Bruno Robert, and Peter Horton: Molecular Configuration of Xanthophyll Cycle Carotenoids in Photosystem II Antenna Complexes
J. Biol. Chem. 2002 277: 42937-42942. First Published on September 1, 2002; doi:10.1074/jbc.M207823200 [Abstract] [Full Text] [PDF]

Sergio Rodríguez-Cuenca, Esperanza Pujol, Roberto Justo, Margalida Frontera, Jordi Oliver, Magdalena Gianotti, and Pilar Roca: Sex-dependent Thermogenesis, Differences in Mitochondrial Morphology and Function, and Adrenergic Response in Brown Adipose Tissue
J. Biol. Chem. 2002 277: 42958-42963. First Published on September 4, 2002; doi:10.1074/jbc.M207229200 [Abstract] [Full Text] [PDF]

Elodie Couplan, Chantal Gelly, Marc Goubern, Christophe Fleury, Bruno Quesson, Mathieu Silberberg, Eric Thiaudière, Philippe Mateo, Michel Lonchampt, Nigel Levens, Catherine de Montrion, Silvia Ortmann, Susanne Klaus, Maria-del-Mar Gonzalez-Barroso, Anne-Marie Cassard-Doulcier, Daniel Ricquier, A. Xavier Bigard, Philippe Diolez, and Frédéric Bouillaud: High Level of Uncoupling Protein 1 Expression in Muscle of Transgenic Mice Selectively Affects Muscles at Rest and Decreases Their IIb Fiber Content
J. Biol. Chem. 2002 277: 43079-43088. First Published on September 6, 2002; doi:10.1074/jbc.M206726200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Yukihiko Okada, Shuhei Yamada, Minako Toyoshima, Jian Dong, Motowo Nakajima, and Kazuyuki Sugahara: Structural Recognition by Recombinant Human Heparanase That Plays Critical Roles in Tumor Metastasis. HIERARCHICAL SULFATE GROUPS WITH DIFFERENTIAL EFFECTS AND THE ESSENTIAL TARGET DISULFATED TRISACCHARIDE SEQUENCE
J. Biol. Chem. 2002 277: 42488-42495. First Published on September 3, 2002; doi:10.1074/jbc.M206510200 [Abstract] [Full Text] [PDF]

Tomoya O. Akama, Anup K. Misra, Ole Hindsgaul, and Michiko N. Fukuda: Enzymatic Synthesis in Vitro of the Disulfated Disaccharide Unit of Corneal Keratan Sulfate
J. Biol. Chem. 2002 277: 42505-42513. First Published on September 5, 2002; doi:10.1074/jbc.M207412200 [Abstract] [Full Text] [PDF]

N. Martin Young, Jean-Robert Brisson, John Kelly, David C. Watson, Luc Tessier, Patricia H. Lanthier, Harold C. Jarrell, Nicolas Cadotte, Frank St. Michael, Erika Aberg, and Christine M. Szymanski: Structure of the N-Linked Glycan Present on Multiple Glycoproteins in the Gram-negative Bacterium, Campylobacter jejuni
J. Biol. Chem. 2002 277: 42530-42539. First Published on August 16, 2002; doi:10.1074/jbc.M206114200 [Abstract] [Full Text] [PDF]

Janet M. Trowbridge, Jennifer A. Rudisill, Dina Ron, and Richard L. Gallo: Dermatan Sulfate Binds and Potentiates Activity of Keratinocyte Growth Factor (FGF-7)
J. Biol. Chem. 2002 277: 42815-42820. First Published on September 4, 2002; doi:10.1074/jbc.M204959200 [Abstract] [Full Text] [PDF]

M. Gabriela Bowden, Livia Visai, Christopher M. Longshaw, Keith T. Holland, Pietro Speziale, and Magnus Höök: Is the GehD Lipase from Staphylococcus epidermidis a Collagen Binding Adhesin?
J. Biol. Chem. 2002 277: 43017-43023. First Published on September 5, 2002; doi:10.1074/jbc.M207921200 [Abstract] [Full Text] [PDF]

Laure Garrigue-Antar, Nichola Hartigan, and Karl E. Kadler: Post-translational Modification of Bone Morphogenetic Protein-1 Is Required for Secretion and Stability of the Protein
J. Biol. Chem. 2002 277: 43327-43334. First Published on September 5, 2002; doi:10.1074/jbc.M207342200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Gary M. Jenkins, L. Ashley Cowart, Paola Signorelli, Benjamin J. Pettus, Charles E. Chalfant, and Yusuf A. Hannun: Acute Activation of de Novo Sphingolipid Biosynthesis upon Heat Shock Causes an Accumulation of Ceramide and Subsequent Dephosphorylation of SR Proteins
J. Biol. Chem. 2002 277: 42572-42578. First Published on August 27, 2002; doi:10.1074/jbc.M207346200 [Abstract] [Full Text] [PDF]

Jean Y. Chen, Beatriz Levy-Wilson, Sheryl Goodart, and Allen D. Cooper: Mice Expressing the Human CYP7A1 Gene in the Mouse CYP7A1 Knock-out Background Lack Induction of CYP7A1 Expression by Cholesterol Feeding and Have Increased Hypercholesterolemia When Fed a High Fat Diet
J. Biol. Chem. 2002 277: 42588-42595. First Published on August 28, 2002; doi:10.1074/jbc.M205117200 [Abstract] [Full Text] [PDF]

Ute Panzenboeck, Zoltan Balazs, Andrea Sovic, Andelko Hrzenjak, Sanja Levak-Frank, Andrea Wintersperger, Ernst Malle, and Wolfgang Sattler: ABCA1 and Scavenger Receptor Class B, Type I, Are Modulators of Reverse Sterol Transport at an in Vitro Blood-Brain Barrier Constituted of Porcine Brain Capillary Endothelial Cells
J. Biol. Chem. 2002 277: 42781-42789. First Published on August 28, 2002; doi:10.1074/jbc.M207601200 [Abstract] [Full Text] [PDF]

Bo Feng and Ira Tabas: ABCA1-mediated Cholesterol Efflux Is Defective in Free Cholesterol-loaded Macrophages. MECHANISM INVOLVES ENHANCED ABCA1 DEGRADATION IN A PROCESS REQUIRING FULL NPC1 ACTIVITY
J. Biol. Chem. 2002 277: 43271-43280. First Published on September 4, 2002; doi:10.1074/jbc.M207532200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Qadeer H. Aziz, Christopher J. Partridge, Tim S. Munsey, and Asipu Sivaprasadarao: Depolarization Induces Intersubunit Cross-linking in a S4 Cysteine Mutant of the Shaker Potassium Channel
J. Biol. Chem. 2002 277: 42719-42725. First Published on August 23, 2002; doi:10.1074/jbc.M207258200 [Abstract] [Full Text] [PDF]

Pernille Bøttger and Lene Pedersen: Two Highly Conserved Glutamate Residues Critical for Type III Sodium-dependent Phosphate Transport Revealed by Uncoupling Transport Function from Retroviral Receptor Function
J. Biol. Chem. 2002 277: 42741-42747. First Published on August 29, 2002; doi:10.1074/jbc.M207096200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Gerrit J. Poelarends and Wil N. Konings: The Transmembrane Domains of the ABC Multidrug Transporter LmrA Form a Cytoplasmic Exposed, Aqueous Chamber within the Membrane
J. Biol. Chem. 2002 277: 42891-42898. First Published on August 14, 2002; doi:10.1074/jbc.M206508200 [Abstract] [Full Text] [PDF]

Amal K. Bera, Maya Chatav, and Myles H. Akabas: GABA_A Receptor M2-M3 Loop Secondary Structure and Changes in Accessibility during Channel Gating
J. Biol. Chem. 2002 277: 43002-43010. First Published on September 10, 2002; doi:10.1074/jbc.M206321200 [Abstract] [Full Text] [PDF]

Christoph Michalski, Yunhai Cui, Anne T. Nies, Andreas K. Nuessler, Peter Neuhaus, Ulrich M. Zanger, Kathrin Klein, Michel Eichelbaum, Dietrich Keppler, and Jörg König: A Naturally Occurring Mutation in the SLC21A6 Gene Causing Impaired Membrane Localization of the Hepatocyte Uptake Transporter
J. Biol. Chem. 2002 277: 43058-43063. First Published on August 23, 2002; doi:10.1074/jbc.M207735200 [Abstract] [Full Text] [PDF]

Lei Hetian, An Ping, Song Shumei, Liu Xiaoying, He Luowen, Wu Jian, Meng Lin, Liu Meisheng, Yang Junshan, and Shou Chengchao: A Novel Peptide Isolated from a Phage Display Library Inhibits Tumor Growth and Metastasis by Blocking the Binding of Vascular Endothelial Growth Factor to Its Kinase Domain Receptor
J. Biol. Chem. 2002 277: 43137-43142. First Published on August 14, 2002; doi:10.1074/jbc.M203103200 [Abstract] [Full Text] [PDF]

Thomas Nebl, Kersi N. Pestonjamasp, John D. Leszyk, Jessica L. Crowley, Sang W. Oh, and Elizabeth J. Luna: Proteomic Analysis of a Detergent-resistant Membrane Skeleton from Neutrophil Plasma Membranes
J. Biol. Chem. 2002 277: 43399-43409. First Published on August 28, 2002; doi:10.1074/jbc.M205386200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ayumu Fukuda, Shin-ichi Matsuyama, Takashi Hara, Jiro Nakayama, Hiromichi Nagasawa, and Hajime Tokuda: Aminoacylation of the N-terminal Cysteine Is Essential for Lol-dependent Release of Lipoproteins from Membranes but Does Not Depend on Lipoprotein Sorting Signals
J. Biol. Chem. 2002 277: 43512-43518. First Published on August 26, 2002; doi:10.1074/jbc.M206816200 [Abstract] [Full Text] [PDF]

Hin C. Lee and Harris D. Bernstein: Trigger Factor Retards Protein Export in Escherichia coli
J. Biol. Chem. 2002 277: 43527-43535. First Published on August 29, 2002; doi:10.1074/jbc.M205950200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Sarah E. Abbey and Lincoln R. Potter: Vasopressin-dependent Inhibition of the C-type Natriuretic Peptide Receptor, NPR-B/GC-B, Requires Elevated Intracellular Calcium Concentrations
J. Biol. Chem. 2002 277: 42423-42430. First Published on August 23, 2002; doi:10.1074/jbc.M206686200 [Abstract] [Full Text] [PDF]

Claire Mulligan, Justin Rochford, Gareth Denyer, Richard Stephens, Giles Yeo, Thomas Freeman, Kenneth Siddle, and Stephen O'Rahilly: Microarray Analysis of Insulin and Insulin-like Growth Factor-1 (IGF-1) Receptor Signaling Reveals the Selective Up-regulation of the Mitogen Heparin-binding EGF-like Growth Factor by IGF-1
J. Biol. Chem. 2002 277: 42480-42487. First Published on September 3, 2002; doi:10.1074/jbc.M206206200 [Abstract] [Full Text] [PDF]

Usamah S. Kayyali, Corin M. Pennella, Carolina Trujillo, Otto Villa, Matthias Gaestel, and Paul M. Hassoun: Cytoskeletal Changes in Hypoxic Pulmonary Endothelial Cells Are Dependent on MAPK-activated Protein Kinase MK2
J. Biol. Chem. 2002 277: 42596-42602. First Published on August 28, 2002; doi:10.1074/jbc.M205863200 [Abstract] [Full Text] [PDF]

Declan F. McCole, Stephen J. Keely, Robert J. Coffey, and Kim E. Barrett: Transactivation of the Epidermal Growth Factor Receptor in Colonic Epithelial Cells by Carbachol Requires Extracellular Release of Transforming Growth Factor- $alpha$
J. Biol. Chem. 2002 277: 42603-42612. First Published on August 28, 2002; doi:10.1074/jbc.M206487200 [Abstract] [Full Text] [PDF]

Jianmin Wu and Ralf Janknecht: Regulation of the ETS Transcription Factor ER81 by the 90-kDa Ribosomal S6 Kinase 1 and Protein Kinase A
J. Biol. Chem. 2002 277: 42669-42679. First Published on September 3, 2002; doi:10.1074/jbc.M205501200 [Abstract] [Full Text] [PDF]

Ko Eto and Hideo Kimura: A Novel Enhancing Mechanism for Hydrogen Sulfide-producing Activity of Cystathionine $beta$ -Synthase
J. Biol. Chem. 2002 277: 42680-42685. First Published on September 3, 2002; doi:10.1074/jbc.M205835200 [Abstract] [Full Text] [PDF]

William R. Franek, Yalamanchali C. Chowdary, Xinchun Lin, Maowen Hu, Edmund J. Miller, Jeffrey A. Kazzaz, Pasquale Razzano, John Romashko, III, Jonathan M. Davis, Pramod Narula, Stuart Horowitz, William Scott, and Lin L. Mantell: Suppression of Nuclear Factor- $kappa$ B Activity by Nitric Oxide and Hyperoxia in Oxygen-resistant Cells
J. Biol. Chem. 2002 277: 42694-42700. First Published on September 4, 2002; doi:10.1074/jbc.M202623200 [Abstract] [Full Text] [PDF]

Jill Stevenson-Paulik, Audrey R. Odom, and John D. York: Molecular and Biochemical Characterization of Two Plant Inositol Polyphosphate 6-/3-/5-Kinases
J. Biol. Chem. 2002 277: 42711-42718. First Published on September 10, 2002; doi:10.1074/jbc.M209112200 [Abstract] [Full Text] [PDF]

H.-C. Huang, Truyen Nguyen, and Cecil B. Pickett: Phosphorylation of Nrf2 at Ser-40 by Protein Kinase C Regulates Antioxidant Response Element-mediated Transcription
J. Biol. Chem. 2002 277: 42769-42774. First Published on August 26, 2002; doi:10.1074/jbc.M206911200 [Abstract] [Full Text] [PDF]

Steven Bozinovski, Jessica E. Jones, Ross Vlahos, John A. Hamilton, and Gary P. Anderson: Granulocyte/Macrophage-Colony-stimulating Factor (GM-CSF) Regulates Lung Innate Immunity to Lipopolysaccharide through Akt/Erk Activation of NF $kappa$ B and AP-1 in Vivo
J. Biol. Chem. 2002 277: 42808-42814. First Published on September 2, 2002; doi:10.1074/jbc.M207840200 [Abstract] [Full Text] [PDF]

Jenny K. S. Shum, J. Andres Melendez, and John J. Jeffrey: Serotonin-induced MMP-13 Production Is Mediated via Phospholipase C, Protein Kinase C, and ERK1/2 in Rat Uterine Smooth Muscle Cells
J. Biol. Chem. 2002 277: 42830-42840. First Published on September 3, 2002; doi:10.1074/jbc.M205094200 [Abstract] [Full Text] [PDF]

Heba O. Barazi, Zhuqing Li, Jo Anne Cashel, Henry C. Krutzsch, Douglas S. Annis, Deane F. Mosher, and David D. Roberts: Regulation of Integrin Function by CD47 Ligands. DIFFERENTIAL EFFECTS ON $alpha$ _v $beta$ ₃ AND $alpha$ ₄ $beta$ ₁ INTEGRIN-MEDIATED ADHESION
J. Biol. Chem. 2002 277: 42859-42866. First Published on September 5, 2002; doi:10.1074/jbc.M206849200 [Abstract] [Full Text] [PDF]

Valérie Gouazé, Nathalie Andrieu-Abadie, Olivier Cuvillier, Sophie Malagarie-Cazenave, Marie-Françoise Frisach, Marc-Edouard Mirault, and Thierry Levade: Glutathione Peroxidase-1 Protects from CD95-induced Apoptosis
J. Biol. Chem. 2002 277: 42867-42874. First Published on September 6, 2002; doi:10.1074/jbc.M203067200 [Abstract] [Full Text] [PDF]

Rotem Karni, Yuval Dor, Eli Keshet, Oded Meyuhas, and Alexander Levitzki: Activated pp60^c-Src Leads to Elevated Hypoxia-inducible Factor (HIF)-1 $alpha$ Expression under Normoxia
J. Biol. Chem. 2002 277: 42919-42925. First Published on August 27, 2002; doi:10.1074/jbc.M206141200 [Abstract] [Full Text] [PDF]

Daniel Martín, Marta Salinas, Naoya Fujita, Takashi Tsuruo, and Antonio Cuadrado: Ceramide and Reactive Oxygen Species Generated by H₂O₂ Induce Caspase-3-independent Degradation of Akt/Protein Kinase B
J. Biol. Chem. 2002 277: 42943-42952. First Published on September 3, 2002; doi:10.1074/jbc.M201070200 [Abstract] [Full Text] [PDF]

William T. Arthur, Shawn M. Ellerbroek, Channing J. Der, Keith Burridge, and Krister Wennerberg: XPLN, a Guanine Nucleotide Exchange Factor for RhoA and RhoB, But Not RhoC
J. Biol. Chem. 2002 277: 42964-42972. First Published on September 6, 2002; doi:10.1074/jbc.M207401200 [Abstract] [Full Text] [PDF]

Hong-Liang Rui, Ernest Fan, Hai-Meng Zhou, Zhen Xu, Yi Zhang, and Sheng-Cai Lin: SUMO-1 Modification of the C-terminal KVEKVD of Axin Is Required for JNK Activation but Has No Effect on Wnt Signaling
J. Biol. Chem. 2002 277: 42981-42986. First Published on September 9, 2002; doi:10.1074/jbc.M208099200 [Abstract] [Full Text] [PDF]

Helmut Glantschnig, Gideon A. Rodan, and Alfred A. Reszka: Mapping of MST1 Kinase Sites of Phosphorylation. ACTIVATION AND AUTOPHOSPHORYLATION
J. Biol. Chem. 2002 277: 42987-42996. First Published on September 9, 2002; doi:10.1074/jbc.M208538200 [Abstract] [Full Text] [PDF]

Tatsuo Tanimoto, Zheng-Gen Jin, and Bradford C. Berk: Transactivation of Vascular Endothelial Growth Factor (VEGF) Receptor Flk-1/KDR Is Involved in Sphingosine 1-Phosphate-stimulated Phosphorylation of Akt and Endothelial Nitric-oxide Synthase (eNOS)
J. Biol. Chem. 2002 277: 42997-43001. First Published on September 10, 2002; doi:10.1074/jbc.M204764200 [Abstract] [Full Text] [PDF]

John M. Schmitt and Philip J. S. Stork: G $alpha$ and G $beta$ $gamma$ Require Distinct Src-dependent Pathways to Activate Rap1 and Ras
J. Biol. Chem. 2002 277: 43024-43032. First Published on September 6, 2002; doi:10.1074/jbc.M204006200 [Abstract] [Full Text] [PDF]

Deanna R. Brickley, Christina A. Mikosz, Christy R. Hagan, and Suzanne D. Conzen: Ubiquitin Modification of Serum and Glucocorticoid-induced Protein Kinase-1 (SGK-1)
J. Biol. Chem. 2002 277: 43064-43070. First Published on September 5, 2002; doi:10.1074/jbc.M207604200 [Abstract] [Full Text] [PDF]

Valérie Perrot, José Vázquez-Prado, and J. Silvio Gutkind: Plexin B Regulates Rho through the Guanine Nucleotide Exchange Factors Leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF
J. Biol. Chem. 2002 277: 43115-43120. First Published on August 14, 2002; doi:10.1074/jbc.M206005200 [Abstract] [Full Text] [PDF]

Christina Lutz, Johannes Nimpf, Marcel Jenny, Karl Boecklinger, Christiane Enzinger, Gerd Utermann, Gabriele Baier-Bitterlich, and Gottfried Baier: Evidence of Functional Modulation of the MEKK/JNK/cJun Signaling Cascade by the Low Density Lipoprotein Receptor-related Protein (LRP)
J. Biol. Chem. 2002 277: 43143-43151. First Published on August 21, 2002; doi:10.1074/jbc.M204426200 [Abstract] [Full Text] [PDF]

Annakaisa Haapasalo, Ilkka Sipola, Kim Larsson, Karl E. O. Åkerman, Peter Stoilov, Stefan Stamm, Garry Wong, and Eero Castrén: Regulation of TRKB Surface Expression by Brain-derived Neurotrophic Factor and Truncated TRKB Isoforms
J. Biol. Chem. 2002 277: 43160-43167. First Published on August 28, 2002; doi:10.1074/jbc.M205202200 [Abstract] [Full Text] [PDF]

Zhao Mei Mu, Xiao Ying Yin, and Edward V. Prochownik: Pag, a Putative Tumor Suppressor, Interacts with the Myc Box II Domain of c-Myc and Selectively Alters Its Biological Function and Target Gene Expression
J. Biol. Chem. 2002 277: 43175-43184. First Published on August 23, 2002; doi:10.1074/jbc.M206066200 [Abstract] [Full Text] [PDF]

Juha Klefstrom, Emmy W. Verschuren, and Gerard Evan: c-Myc Augments the Apoptotic Activity of Cytosolic Death Receptor Signaling Proteins by Engaging the Mitochondrial Apoptotic Pathway
J. Biol. Chem. 2002 277: 43224-43232. First Published on August 28, 2002; doi:10.1074/jbc.M206967200 [Abstract] [Full Text] [PDF]

Jessica L. DeGraff, Vsevolod V. Gurevich, and Jeffrey L. Benovic: The Third Intracellular Loop of $alpha$ ₂-Adrenergic Receptors Determines Subtype Specificity of Arrestin Interaction
J. Biol. Chem. 2002 277: 43247-43252. First Published on August 29, 2002; doi:10.1074/jbc.M207495200 [Abstract] [Full Text] [PDF]

Gouri Ranganathan, Dan Phan, Irina D. Pokrovskaya, Joan E. McEwen, Chunling Li, and Philip A. Kern: The Translational Regulation of Lipoprotein Lipase by Epinephrine Involves an RNA Binding Complex Including the Catalytic Subunit of Protein Kinase A
J. Biol. Chem. 2002 277: 43281-43287. First Published on September 5, 2002; doi:10.1074/jbc.M202560200 [Abstract] [Full Text] [PDF]

Raju V. S. Rajala, Mark E. McClellan, John D. Ash, and Robert E. Anderson: In Vivo Regulation of Phosphoinositide 3-Kinase in Retina through Light-induced Tyrosine Phosphorylation of the Insulin Receptor $beta$ -Subunit
J. Biol. Chem. 2002 277: 43319-43326. First Published on September 3, 2002; doi:10.1074/jbc.M206355200 [Abstract] [Full Text] [PDF]

Jiwei Wang, Lora W. Barsky, Chung H. Shum, Ambrose Jong, Kenneth I. Weinberg, Steven J. Collins, Timothy J. Triche, and Lingtao Wu: Retinoid-induced G₁ Arrest and Differentiation Activation Are Associated with a Switch to Cyclin-dependent Kinase-activating Kinase Hypophosphorylation of Retinoic Acid Receptor $alpha$
J. Biol. Chem. 2002 277: 43369-43376. First Published on September 3, 2002; doi:10.1074/jbc.M206792200 [Abstract] [Full Text] [PDF]

Gra $z$ yna Nowak: Protein Kinase C- $alpha$ and ERK1/2 Mediate Mitochondrial Dysfunction, Decreases in Active Na⁺ Transport, and Cisplatin-induced Apoptosis in Renal Cells
J. Biol. Chem. 2002 277: 43377-43388. First Published on September 5, 2002; doi:10.1074/jbc.M206373200 [Abstract] [Full Text] [PDF]

Masashi Isshiki, Yun-shu Ying, Toshiro Fujita, and Richard G. W. Anderson: A Molecular Sensor Detects Signal Transduction from Caveolae in Living Cells
J. Biol. Chem. 2002 277: 43389-43398. First Published on August 12, 2002; doi:10.1074/jbc.M205411200 [Abstract] [Full Text] [PDF]

Jingwei Meng and Patrick J. Casey: Activation of G_z Attenuates Rap1-mediated Differentiation of PC12 Cells
J. Biol. Chem. 2002 277: 43417-43424. First Published on August 26, 2002; doi:10.1074/jbc.M204074200 [Abstract] [Full Text] [PDF]

Jordi Torres, Charles J. Di Como, Enrique Herrero, and Maria Angeles de la Torre-Ruiz: Regulation of the Cell Integrity Pathway by Rapamycin-sensitive TOR Function in Budding Yeast
J. Biol. Chem. 2002 277: 43495-43504. First Published on August 8, 2002; doi:10.1074/jbc.M205408200 [Abstract] [Full Text] [PDF]

Fumio Sakane, Shin-ichi Imai, Keiko Yamada, Tomohiro Murakami, Shuichi Tsushima, and Hideo Kanoh: Alternative Splicing of the Human Diacylglycerol Kinase $delta$ Gene Generates Two Isoforms Differing in Their Expression Patterns and in Regulatory Functions
J. Biol. Chem. 2002 277: 43519-43526. First Published on August 27, 2002; doi:10.1074/jbc.M206895200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Natalia A. Riobó, Mariana Melani, Norberto Sanjuán, Mónica L. Fiszman, María Clara Gravielle, M. Cecilia Carreras, Enrique Cadenas, and Juan J. Poderoso: The Modulation of Mitochondrial Nitric-oxide Synthase Activity in Rat Brain Development
J. Biol. Chem. 2002 277: 42447-42455. First Published on August 28, 2002; doi:10.1074/jbc.M204580200 [Abstract] [Full Text] [PDF]

Cori N. Newton, Jennifer G. DeLuca, Richard H. Himes, Herbert P. Miller, Mary Ann Jordan, and Leslie Wilson: Intrinsically Slow Dynamic Instability of HeLa Cell Microtubules in Vitro
J. Biol. Chem. 2002 277: 42456-42462. First Published on August 30, 2002; doi:10.1074/jbc.M207134200 [Abstract] [Full Text] [PDF]

Yufang Zheng, Johannes Schlöndorff, and Carl P. Blobel: Evidence for Regulation of the Tumor Necrosis Factor $alpha$ -Convertase (TACE) by Protein-tyrosine Phosphatase PTPH1
J. Biol. Chem. 2002 277: 42463-42470. First Published on August 30, 2002; doi:10.1074/jbc.M207459200 [Abstract] [Full Text] [PDF]

Patricia B. Cornet, Christine Picquet, Pascale Lemoine, Kevin G. Osteen, Kaylon L. Bruner-Tran, Siamak Tabibzadeh, Pierre J. Courtoy, Yves Eeckhout, Etienne Marbaix, and Patrick Henriet: Regulation and Function of LEFTY-A/EBAF in the Human Endometrium. mRNA EXPRESSION DURING THE MENSTRUAL CYCLE, CONTROL BY PROGESTERONE, AND EFFECT ON MATRIX METALLOPROTEINASES
J. Biol. Chem. 2002 277: 42496-42504. First Published on September 4, 2002; doi:10.1074/jbc.M201793200 [Abstract] [Full Text] [PDF]

Nanyun Tang, Tianming Lin, and E. Michael Ostap: Dynamics of Myo1c (Myosin-I $beta$ ) Lipid Binding and Dissociation
J. Biol. Chem. 2002 277: 42763-42768. First Published on September 6, 2002; doi:10.1074/jbc.M206388200 [Abstract] [Full Text] [PDF]

Kyoko Okada, Laurent Blanchoin, Hiroshi Abe, Hui Chen, Thomas D. Pollard, and James R. Bamburg: Xenopus Actin-interacting Protein 1 (XAip1) Enhances Cofilin Fragmentation of Filaments by Capping Filament Ends
J. Biol. Chem. 2002 277: 43011-43016. First Published on June 7, 2002; doi:10.1074/jbc.M203111200 [Abstract] [Full Text] [PDF]

Katell Peoc'h, Catherine Serres, Yveline Frobert, Caroline Martin, Sylvain Lehmann, Stéphanie Chasseigneaux, Véronique Sazdovitch, Jacques Grassi, Pierre Jouannet, Jean-Marie Launay, and Jean-Louis Laplanche: The Human "Prion-like" Protein Doppel Is Expressed in Both Sertoli Cells and Spermatozoa
J. Biol. Chem. 2002 277: 43071-43078. First Published on August 27, 2002; doi:10.1074/jbc.M206357200 [Abstract] [Full Text] [PDF]

Mitsunori Fukuda and Taruho S. Kuroda: Slac2-c (Synaptotagmin-like Protein Homologue Lacking C2 Domains-c), a Novel Linker Protein that Interacts with Rab27, Myosin Va/VIIa, and Actin
J. Biol. Chem. 2002 277: 43096-43103. First Published on September 7, 2002; doi:10.1074/jbc.M203862200 [Abstract] [Full Text] [PDF]

Julian Ik Tsen Heng and Seong-Seng Tan: Cloning and Characterization of GRIPE, a Novel Interacting Partner of the Transcription Factor E12 in Developing Mouse Forebrain
J. Biol. Chem. 2002 277: 43152-43159. First Published on August 27, 2002; doi:10.1074/jbc.M204858200 [Abstract] [Full Text] [PDF]

Andrea Krempler, MaLinda D. Henry, Aleata A. Triplett, and Kay-Uwe Wagner: Targeted Deletion of the Tsg101 Gene Results in Cell Cycle Arrest at G₁/S and p53-independent Cell Death
J. Biol. Chem. 2002 277: 43216-43223. First Published on August 29, 2002; doi:10.1074/jbc.M207662200 [Abstract] [Full Text] [PDF]

Xuejiao Wang, Siqun Xu, Carlo Rivolta, Lili Y. Li, Guang-Hua Peng, Prabodh K. Swain, Ching-Hwa Sung, Anand Swaroop, Eliot L. Berson, Thaddeus P. Dryja, and Shiming Chen: Barrier to Autointegration Factor Interacts with the Cone-Rod Homeobox and Represses Its Transactivation Function
J. Biol. Chem. 2002 277: 43288-43300. First Published on September 4, 2002; doi:10.1074/jbc.M207952200 [Abstract] [Full Text] [PDF]

Sue J. Sohn, Brieana K. Sarvis, Dragana Cado, and Astar Winoto: ERK5 MAPK Regulates Embryonic Angiogenesis and Acts as a Hypoxia-sensitive Repressor of Vascular Endothelial Growth Factor Expression
J. Biol. Chem. 2002 277: 43344-43351. First Published on September 6, 2002; doi:10.1074/jbc.M207573200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Nagendra Yadava, Prasanth Potluri, Erin N. Smith, Amina Bisevac, and Immo E. Scheffler: Species-specific and mutant MWFE proteins. Their effect on the assembly of a functional mammalian mitochondrial complex I.
J. Biol. Chem. 2002 277: 43544. [Full Text] [PDF]