JBC -- Table of Contents (Nov 15 2002, 277, (46))

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Abner Louis Notkins: Immunologic and Genetic Factors in Type 1 Diabetes
J. Biol. Chem. 2002 277: 43545-43548. First Published on September 20, 2002; doi:10.1074/jbc.R200012200 [Full Text] [PDF]

Accelerated Publications:

Katsumi Fukamachi, Yoichiro Matsuoka, Hiroshi Ohno, Tetsuya Hamaguchi, and Hiroyuki Tsuda: Neuronal Leucine-rich Repeat Protein-3 Amplifies MAPK Activation by Epidermal Growth Factor through a Carboxyl-terminal Region Containing Endocytosis Motifs
J. Biol. Chem. 2002 277: 43549-43552. First Published on September 23, 2002; doi:10.1074/jbc.C200502200 [Abstract] [Full Text] [PDF]

Mei Zhang, Eugenia Mileykovskaya, and William Dowhan: Gluing the Respiratory Chain Together. CARDIOLIPIN IS REQUIRED FOR SUPERCOMPLEX FORMATION IN THE INNER MITOCHONDRIAL MEMBRANE
J. Biol. Chem. 2002 277: 43553-43556. First Published on October 2, 2002; doi:10.1074/jbc.C200551200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Stephen Van Komen, Galina Petukhova, Stefan Sigurdsson, and Patrick Sung: Functional Cross-talk among Rad51, Rad54, and Replication Protein A in Heteroduplex DNA Joint Formation
J. Biol. Chem. 2002 277: 43578-43587. First Published on September 10, 2002; doi:10.1074/jbc.M205864200 [Abstract] [Full Text] [PDF]

Janina Cramer, Michael Strerath, Andreas Marx, and Tobias Restle: Exploring the Effects of Active Site Constraints on HIV-1 Reverse Transcriptase DNA Polymerase Fidelity
J. Biol. Chem. 2002 277: 43593-43598. First Published on August 27, 2002; doi:10.1074/jbc.M207854200 [Abstract] [Full Text] [PDF]

Yong-Joo Jeong, Dong-Eun Kim, and Smita S. Patel: Kinetic Pathway of dTTP Hydrolysis by Hexameric T7 Helicase-Primase in the Absence of DNA
J. Biol. Chem. 2002 277: 43778-43784. First Published on September 10, 2002; doi:10.1074/jbc.M208634200 [Abstract] [Full Text] [PDF]

Pia Roos-Mattjus, Benjamin T. Vroman, Matthew A. Burtelow, Matthew Rauen, Alex K. Eapen, and Larry M. Karnitz: Genotoxin-induced Rad9-Hus1-Rad1 (9-1-1) Chromatin Association Is an Early Checkpoint Signaling Event
J. Biol. Chem. 2002 277: 43809-43812. First Published on September 11, 2002; doi:10.1074/jbc.M207272200 [Abstract] [Full Text] [PDF]

Steven P. Angus, Linda J. Wheeler, Sejal A. Ranmal, Xiaoping Zhang, Michael P. Markey, Christopher K. Mathews, and Erik S. Knudsen: Retinoblastoma Tumor Suppressor Targets dNTP Metabolism to Regulate DNA Replication
J. Biol. Chem. 2002 277: 44376-44384. First Published on September 6, 2002; doi:10.1074/jbc.M205911200 [Abstract] [Full Text] [PDF]

Konstantinos Kiakos, Tiffany T. Howard, Moses Lee, John A. Hartley, and Peter J. McHugh: Saccharomyces cerevisiae RAD5 Influences the Excision Repair of DNA Minor Groove Adducts
J. Biol. Chem. 2002 277: 44576-44581. First Published on September 10, 2002; doi:10.1074/jbc.M208169200 [Abstract] [Full Text] [PDF]

Yanbin Zhang, Xiaohua Wu, Dongyu Guo, Olga Rechkoblit, John-Stephen Taylor, Nicholas E. Geacintov, and Zhigang Wang: Lesion Bypass Activities of Human DNA Polymerase µ
J. Biol. Chem. 2002 277: 44582-44587. First Published on September 12, 2002; doi:10.1074/jbc.M207297200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Ling He, Martin J. J. Ronis, and Thomas M. Badger: Ethanol Induction of Class I Alcohol Dehydrogenase Expression in the Rat Occurs through Alterations in CCAAT/Enhancer Binding Proteins $beta$ and $gamma$
J. Biol. Chem. 2002 277: 43572-43577. First Published on September 3, 2002; doi:10.1074/jbc.M204535200 [Abstract] [Full Text] [PDF]

Günter Schneider, Franz Oswald, Christian Wahl, Florian R. Greten, Guido Adler, and Roland M. Schmid: Cyclosporine Inhibits Growth through the Activating Transcription Factor/cAMP-responsive Element-binding Protein Binding Site in the Cyclin D1 Promoter
J. Biol. Chem. 2002 277: 43599-43607. First Published on September 4, 2002; doi:10.1074/jbc.M204787200 [Abstract] [Full Text] [PDF]

Felix Grün, Ranga N. Venkatesan, Michelle M. Tabb, Changcheng Zhou, Junran Cao, Daniel Hemmati, and Bruce Blumberg: Benzoate X Receptors $alpha$ and $beta$ Are Pharmacologically Distinct and Do Not Function as Xenobiotic Receptors
J. Biol. Chem. 2002 277: 43691-43697. First Published on August 26, 2002; doi:10.1074/jbc.M206553200 [Abstract] [Full Text] [PDF]

Marta Kolodziejczak, Anna Kolaczkowska, Bartosz Szczesny, Adam Urantowka, Carina Knorpp, Jan Kieleczawa, and Hanna Janska: A Higher Plant Mitochondrial Homologue of the Yeast m-AAA Protease. MOLECULAR CLONING, LOCALIZATION, AND PUTATIVE FUNCTION
J. Biol. Chem. 2002 277: 43792-43798. First Published on September 11, 2002; doi:10.1074/jbc.M203831200 [Abstract] [Full Text] [PDF]

Tilman Sánchez-Elsner, Luisa M. Botella, Beatriz Velasco, Carmen Langa, and Carmelo Bernabéu: Endoglin Expression Is Regulated by Transcriptional Cooperation between the Hypoxia and Transforming Growth Factor- $beta$ Pathways
J. Biol. Chem. 2002 277: 43799-43808. First Published on September 11, 2002; doi:10.1074/jbc.M207160200 [Abstract] [Full Text] [PDF]

Johnathan R. Whetstine, Teah L. Witt, and Larry H. Matherly: The Human Reduced Folate Carrier Gene Is Regulated by the AP2 and Sp1 Transcription Factor Families and a Functional 61-Base Pair Polymorphism
J. Biol. Chem. 2002 277: 43873-43880. First Published on September 12, 2002; doi:10.1074/jbc.M208296200 [Abstract] [Full Text] [PDF]

Heather L. Wilson, Pamela J. McFie, and William J. Roesler: Different Transcription Factor Binding Arrays Modulate the cAMP Responsivity of the Phosphoenolpyruvate Carboxykinase Gene Promoter
J. Biol. Chem. 2002 277: 43895-43902. First Published on September 16, 2002; doi:10.1074/jbc.M203169200 [Abstract] [Full Text] [PDF]

Christos Chadjichristos, Chafik Ghayor, Jean-François Herrouin, Leena Ala-Kokko, Gunthram Suske, Jean-Pierre Pujol, and Philippe Galéra: Down-regulation of Human Type II Collagen Gene Expression by Transforming Growth Factor- $beta$ 1 (TGF- $beta$ 1) in Articular Chondrocytes Involves SP3/SP1 Ratio
J. Biol. Chem. 2002 277: 43903-43917. First Published on August 16, 2002; doi:10.1074/jbc.M206111200 [Abstract] [Full Text] [PDF]

Meir H. Scheinfeld, Enrico Ghersi, Karen Laky, B. J. Fowlkes, and Luciano D'Adamio: Processing of $beta$ -Amyloid Precursor-like Protein-1 and -2 by $gamma$ -Secretase Regulates Transcription
J. Biol. Chem. 2002 277: 44195-44201. First Published on September 12, 2002; doi:10.1074/jbc.M208110200 [Abstract] [Full Text] [PDF]

Tilman Borggrefe, Ralph Davis, Hediye Erdjument-Bromage, Paul Tempst, and Roger D. Kornberg: A Complex of the Srb8, -9, -10, and -11 Transcriptional Regulatory Proteins from Yeast
J. Biol. Chem. 2002 277: 44202-44207. First Published on August 27, 2002; doi:10.1074/jbc.M207195200 [Abstract] [Full Text] [PDF]

Shahana S. Mahajan, Markus M. Little, Rafael Vazquez, and Angus C. Wilson: Interaction of HCF-1 with a Cellular Nuclear Export Factor
J. Biol. Chem. 2002 277: 44292-44299. First Published on September 15, 2002; doi:10.1074/jbc.M205440200 [Abstract] [Full Text] [PDF]

Marie-Hélène Quentien, Isabelle Manfroid, Daniel Moncet, Ginette Gunz, Marc Muller, Michel Grino, Alain Enjalbert, and Isabelle Pellegrini: Pitx Factors Are Involved in Basal and Hormone-regulated Activity of the Human Prolactin Promoter
J. Biol. Chem. 2002 277: 44408-44416. First Published on September 9, 2002; doi:10.1074/jbc.M207824200 [Abstract] [Full Text] [PDF]

Julie M. Hall and Kenneth S. Korach: Analysis of the Molecular Mechanisms of Human Estrogen Receptors $alpha$ and $beta$ Reveals Differential Specificity in Target Promoter Regulation by Xenoestrogens
J. Biol. Chem. 2002 277: 44455-44461. First Published on August 27, 2002; doi:10.1074/jbc.M200849200 [Abstract] [Full Text] [PDF]

Miri Bidder, Jian-Su Shao, Nichole Charlton-Kachigian, Arleen P. Loewy, Clay F. Semenkovich, and Dwight A. Towler: Osteopontin Transcription in Aortic Vascular Smooth Muscle Cells Is Controlled by Glucose-regulated Upstream Stimulatory Factor and Activator Protein-1 Activities
J. Biol. Chem. 2002 277: 44485-44496. First Published on August 27, 2002; doi:10.1074/jbc.M206235200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Maurizio Romano, Roberto Marcucci, Emanuele Buratti, Youhna M. Ayala, Gianfranco Sebastio, and Francisco E. Baralle: Regulation of 3' Splice Site Selection in the 844ins68 Polymorphism of the Cystathionine $beta$ -Synthase Gene
J. Biol. Chem. 2002 277: 43821-43829. First Published on September 12, 2002; doi:10.1074/jbc.M208107200 [Abstract] [Full Text] [PDF]

Meijuan Zhao, Dan Tang, Stanislav Lechpammer, Alexander Hoffman, Alexzander Asea, Mary Ann Stevenson, and Stuart K. Calderwood: Double-stranded RNA-dependent Protein Kinase (pkr) Is Essential for Thermotolerance, Accumulation of HSP70, and Stabilization of ARE-containing HSP70 mRNA during Stress
J. Biol. Chem. 2002 277: 44539-44547. First Published on August 30, 2002; doi:10.1074/jbc.M208408200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Ping Jin, Thomas M. Weiger, and Irwin B. Levitan: Reciprocal Modulation between the $alpha$ and $beta$ 4 Subunits of hSlo Calcium-dependent Potassium Channels
J. Biol. Chem. 2002 277: 43724-43729. First Published on September 9, 2002; doi:10.1074/jbc.M205795200 [Abstract] [Full Text] [PDF]

Stefan Richter and Gayle K. Lamppa: Determinants for Removal and Degradation of Transit Peptides of Chloroplast Precursor Proteins
J. Biol. Chem. 2002 277: 43888-43894. First Published on September 13, 2002; doi:10.1074/jbc.M206020200 [Abstract] [Full Text] [PDF]

Colin Hanfrey, Marina Franceschetti, Melinda J. Mayer, Crista Illingworth, and Anthony J. Michael: Abrogation of Upstream Open Reading Frame-mediated Translational Control of a Plant S-Adenosylmethionine Decarboxylase Results in Polyamine Disruption and Growth Perturbations
J. Biol. Chem. 2002 277: 44131-44139. First Published on August 29, 2002; doi:10.1074/jbc.M206161200 [Abstract] [Full Text] [PDF]

Kathleen C. Day, Michael T. McCabe, Xin Zhao, Yuzhuo Wang, Joanne N. Davis, John Phillips, Marion Von Geldern, Thomas Ried, Mark A. KuKuruga, Gerald R. Cunha, Simon W. Hayward, and Mark L. Day: Rescue of Embryonic Epithelium Reveals That the Homozygous Deletion of the Retinoblastoma Gene Confers Growth Factor Independence and Immortality but Does Not Influence Epithelial Differentiation or Tissue Morphogenesis
J. Biol. Chem. 2002 277: 44475-44484. First Published on August 20, 2002; doi:10.1074/jbc.M205361200 [Abstract] [Full Text] [PDF]

Martin Obin, Bruce Y. Lee, Gretchen Meinke, Andrew Bohm, Rehwa H. Lee, Rachelle Gaudet, Johnathan A. Hopp, Vadim Y. Arshavsky, Barry M. Willardson, and Allen Taylor: Ubiquitylation of the Transducin $beta$ $gamma$ Subunit Complex. REGULATION BY PHOSDUCIN
J. Biol. Chem. 2002 277: 44566-44575. First Published on September 4, 2002; doi:10.1074/jbc.M205308200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Jan D. H. Jongbloed, Haike Antelmann, Michael Hecker, Reindert Nijland, Sierd Bron, Ulla Airaksinen, Frens Pries, Wim J. Quax, Jan Maarten van Dijl, and Peter G. Braun: Selective Contribution of the Twin-Arginine Translocation Pathway to Protein Secretion in Bacillus subtilis
J. Biol. Chem. 2002 277: 44068-44078. First Published on September 5, 2002; doi:10.1074/jbc.M203191200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Lise B. Husted, Esben S. Sørensen, Peter B. Armstrong, James P. Quigley, Lene Kristensen, and Lars Sottrup-Jensen: Localization of Carbohydrate Attachment Sites and Disulfide Bridges in Limulus $alpha$ ₂-Macroglobulin. EVIDENCE FOR TWO FORMS DIFFERING PRIMARILY IN THEIR BAIT REGION SEQUENCES
J. Biol. Chem. 2002 277: 43698-43706. First Published on September 5, 2002; doi:10.1074/jbc.M208236200 [Abstract] [Full Text] [PDF]

Andrey A. Komissarov, Paul J. Declerck, and Joseph D. Shore: Mechanisms of Conversion of Plasminogen Activator Inhibitor 1 from a Suicide Inhibitor to a Substrate by Monoclonal Antibodies
J. Biol. Chem. 2002 277: 43858-43865. First Published on September 9, 2002; doi:10.1074/jbc.M204110200 [Abstract] [Full Text] [PDF]

Wen-Quan Zou and Neil R. Cashman: Acidic pH and Detergents Enhance in Vitro Conversion of Human Brain PrP^C to a PrP^Sc-like Form
J. Biol. Chem. 2002 277: 43942-43947. First Published on August 2, 2002; doi:10.1074/jbc.M203611200 [Abstract] [Full Text] [PDF]

Jarkko Valjakka, Ari Hemminki, Seija Niemi, Hans Söderlund, Kristiina Takkinen, and Juha Rouvinen: Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone. IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS
J. Biol. Chem. 2002 277: 44021-44027. First Published on August 23, 2002; doi:10.1074/jbc.M208392200 [Abstract] [Full Text] [PDF]

Tariq A. Tahir, Jean-Guy Berrin, Ruth Flatman, Alain Roussel, Peter Roepstorff, Gary Williamson, and Nathalie Juge: Specific Characterization of Substrate and Inhibitor Binding Sites of a Glycosyl Hydrolase Family 11 Xylanase from Aspergillus niger
J. Biol. Chem. 2002 277: 44035-44043. First Published on August 30, 2002; doi:10.1074/jbc.M205657200 [Abstract] [Full Text] [PDF]

Fabrizio Gentile, Pietro Amodeo, Ferdinando Febbraio, Francesco Picaro, Andrea Motta, Silvestro Formisano, and Roberto Nucci: SDS-resistant Active and Thermostable Dimers Are Obtained from the Dissociation of Homotetrameric $beta$ -Glycosidase from Hyperthermophilic Sulfolobus solfataricus in SDS. STABILIZING ROLE OF THE A-C INTERMONOMERIC INTERFACE
J. Biol. Chem. 2002 277: 44050-44060. First Published on September 3, 2002; doi:10.1074/jbc.M206761200 [Abstract] [Full Text] [PDF]

Irene M. C. van Amsterdam, Marcellus Ubbink, Marieke van den Bosch, Frederik Rotsaert, Joann Sanders-Loehr, and Gerard W. Canters: A New Type 2 Copper Cysteinate Azurin. INVOLVEMENT OF AN ENGINEERED EXPOSED CYSTEINE IN COPPER BINDING THROUGH INTERNAL REARRANGEMENT
J. Biol. Chem. 2002 277: 44121-44130. First Published on August 16, 2002; doi:10.1074/jbc.M202977200 [Abstract] [Full Text] [PDF]

Takako Sasaki, Pjotr G. Knyazev, Yuri Cheburkin, Walter Göhring, Dominic Tisi, Axel Ullrich, Rupert Timpl, and Erhard Hohenester: Crystal Structure of a C-terminal Fragment of Growth Arrest-specific Protein Gas6. RECEPTOR TYROSINE KINASE ACTIVATION BY LAMININ G-LIKE DOMAINS
J. Biol. Chem. 2002 277: 44164-44170. First Published on September 5, 2002; doi:10.1074/jbc.M207340200 [Abstract] [Full Text] [PDF]

J. Sivaraman, Véronique Sauvé, Allan Matte, and Miroslaw Cygler: Crystal Structure of Escherichia coli Glucose-1-Phosphate Thymidylyltransferase (RffH) Complexed with dTTP and Mg²⁺
J. Biol. Chem. 2002 277: 44214-44219. First Published on August 8, 2002; doi:10.1074/jbc.M206932200 [Abstract] [Full Text] [PDF]

Tatsuki Kashiwagi, Kei-ichi Yokoyama, Kohki Ishikawa, Kunio Ono, Daisuke Ejima, Hiroshi Matsui, and Ei-ichiro Suzuki: Crystal Structure of Microbial Transglutaminase from Streptoverticillium mobaraense
J. Biol. Chem. 2002 277: 44252-44260. First Published on September 7, 2002; doi:10.1074/jbc.M203933200 [Abstract] [Full Text] [PDF]

Xingxing Zang, Paul Taylor, Ji Ming Wang, David J. Meyer, Alan L. Scott, Malcolm D. Walkinshaw, and Rick M. Maizels: Homologues of Human Macrophage Migration Inhibitory Factor from a Parasitic Nematode. GENE CLONING, PROTEIN ACTIVITY, AND CRYSTAL STRUCTURE
J. Biol. Chem. 2002 277: 44261-44267. First Published on September 6, 2002; doi:10.1074/jbc.M204655200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Günther Regelsberger, Werner Atzenhofer, Florian Rüker, Günter A. Peschek, Christa Jakopitsch, Martina Paumann, Paul Georg Furtmüller, and Christian Obinger: Biochemical Characterization of a Membrane-bound Manganese-containing Superoxide Dismutase from the Cyanobacterium Anabaena PCC 7120
J. Biol. Chem. 2002 277: 43615-43622. First Published on September 4, 2002; doi:10.1074/jbc.M207691200 [Abstract] [Full Text] [PDF]

Dalia Shallom, Valery Belakhov, Dmitry Solomon, Gil Shoham, Timor Baasov, and Yuval Shoham: Detailed Kinetic Analysis and Identification of the Nucleophile in $alpha$ -L-Arabinofuranosidase from Geobacillus stearothermophilus T-6, a Family 51 Glycoside Hydrolase
J. Biol. Chem. 2002 277: 43667-43673. First Published on September 6, 2002; doi:10.1074/jbc.M208285200 [Abstract] [Full Text] [PDF]

Masafumi Ito, Urbain Tchoua, Mitsuhiro Okamoto, and Hiromasa Tojo: Purification and Properties of a Phospholipase A₂/Lipase Preferring Phosphatidic Acid, Bis(monoacylglycerol) Phosphate, and Monoacylglycerol from Rat Testis
J. Biol. Chem. 2002 277: 43674-43681. First Published on September 9, 2002; doi:10.1074/jbc.M202817200 [Abstract] [Full Text] [PDF]

Katarzyna Potrykus, Grzegorz Wegrzyn, and V. James Hernandez: Multiple Mechanisms of Transcription Inhibition by ppGpp at the $lambda$ p_R Promoter
J. Biol. Chem. 2002 277: 43785-43791. First Published on September 10, 2002; doi:10.1074/jbc.M208768200 [Abstract] [Full Text] [PDF]

T. Govind Pai, Kei Ohkimoto, Yoichi Sakakibara, Masahito Suiko, Takuya Sugahara, and Ming-Cheh Liu: Manganese Stimulation and Stereospecificity of the Dopa (3,4-Dihydroxyphenylalanine)/Tyrosine-sulfating Activity of Human Monoamine-form Phenol Sulfotransferase. KINETIC STUDIES OF THE MECHANISM USING WILD-TYPE AND MUTANT ENZYMES
J. Biol. Chem. 2002 277: 43813-43820. First Published on September 12, 2002; doi:10.1074/jbc.M200785200 [Abstract] [Full Text] [PDF]

Michel Nauze, Lauriane Gonin, Brigitte Chaminade, Christine Perès, Françoise Hullin-Matsuda, Bertrand Perret, Hugues Chap, and Ama Gassama-Diagne: Guinea Pig Phospholipase B, Identification of the Catalytic Serine and the Proregion Involved in Its Processing and Enzymatic Activity
J. Biol. Chem. 2002 277: 44093-44099. First Published on August 22, 2002; doi:10.1074/jbc.M205761200 [Abstract] [Full Text] [PDF]

Seiji Tsuboi, Yoshifumi Kotani, Ken'ichi Ogawa, Tadashi Hatanaka, Shouki Yatsushiro, Masato Otsuka, and Yoshinori Moriyama: An Intramolecular Disulfide Bridge as a Catalytic Switch for Serotonin N-Acetyltransferase
J. Biol. Chem. 2002 277: 44229-44235. First Published on September 4, 2002; doi:10.1074/jbc.M203305200 [Abstract] [Full Text] [PDF]

Nicole Foeger, Walter Glaser, and Tim Skern: Recognition of Eukaryotic Initiation Factor 4G Isoforms by Picornaviral Proteinases
J. Biol. Chem. 2002 277: 44300-44309. First Published on September 11, 2002; doi:10.1074/jbc.M208006200 [Abstract] [Full Text] [PDF]

Barbara Barylko, Pawel Wlodarski, Derk D. Binns, Stefan H. Gerber, Svetlana Earnest, Thomas C. Sudhof, Nikolai Grichine, and Joseph P. Albanesi: Analysis of the Catalytic Domain of Phosphatidylinositol 4-Kinase Type II
J. Biol. Chem. 2002 277: 44366-44375. First Published on September 4, 2002; doi:10.1074/jbc.M203241200 [Abstract] [Full Text] [PDF]

Mitsuko Hashiguchi, Taro Saito, Shin-ichi Hisanaga, and Toshio Hashiguchi: Truncation of CDK5 Activator p35 Induces Intensive Phosphorylation of Ser²⁰²/Thr²⁰⁵ of Human Tau
J. Biol. Chem. 2002 277: 44525-44530. First Published on September 10, 2002; doi:10.1074/jbc.M207426200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Deborah A. Berthold, Nina Voevodskaya, Pål Stenmark, Astrid Gräslund, and Pär Nordlund: EPR Studies of the Mitochondrial Alternative Oxidase. EVIDENCE FOR A DIIRON CARBOXYLATE CENTER
J. Biol. Chem. 2002 277: 43608-43614. First Published on September 4, 2002; doi:10.1074/jbc.M206724200 [Abstract] [Full Text] [PDF]

Denis Rontein, Martine Dieuaide-Noubhani, Erick J. Dufourc, Philippe Raymond, and Dominique Rolin: The Metabolic Architecture of Plant Cells. STABILITY OF CENTRAL METABOLISM AND FLEXIBILITY OF ANABOLIC PATHWAYS DURING THE GROWTH CYCLE OF TOMATO CELLS
J. Biol. Chem. 2002 277: 43948-43960. First Published on September 10, 2002; doi:10.1074/jbc.M206366200 [Abstract] [Full Text] [PDF]

Elisa Cabiscol, Gemma Bellí, Jordi Tamarit, Pedro Echave, Enrique Herrero, and Joaquim Ros: Mitochondrial Hsp60, Resistance to Oxidative Stress, and the Labile Iron Pool Are Closely Connected in Saccharomyces cerevisiae
J. Biol. Chem. 2002 277: 44531-44538. First Published on August 27, 2002; doi:10.1074/jbc.M206525200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Rui-Zhu Zhang, Patrizia Sabatelli, Te-Cheng Pan, Stefano Squarzoni, Elisabetta Mattioli, Enrico Bertini, Guglielmina Pepe, and Mon-Li Chu: Effects on Collagen VI mRNA Stability and Microfibrillar Assembly of Three COL6A2 Mutations in Two Families with Ullrich Congenital Muscular Dystrophy
J. Biol. Chem. 2002 277: 43557-43564. First Published on September 5, 2002; doi:10.1074/jbc.M207696200 [Abstract] [Full Text] [PDF]

Wojciech J. Grzesik, Chester R. Frazier, Jay R. Shapiro, Paul D. Sponseller, Pamela Gehron Robey, and Neal S. Fedarko: Age-related Changes in Human Bone Proteoglycan Structure. IMPACT OF OSTEOGENESIS IMPERFECTA
J. Biol. Chem. 2002 277: 43638-43647. First Published on September 6, 2002; doi:10.1074/jbc.M202124200 [Abstract] [Full Text] [PDF]

Sarama Sathyaseelan Deepa, Yuko Umehara, Shigeki Higashiyama, Nobuyuki Itoh, and Kazuyuki Sugahara: Specific Molecular Interactions of Oversulfated Chondroitin Sulfate E with Various Heparin-binding Growth Factors. IMPLICATIONS AS A PHYSIOLOGICAL BINDING PARTNER IN THE BRAIN AND OTHER TISSUES
J. Biol. Chem. 2002 277: 43707-43716. First Published on September 6, 2002; doi:10.1074/jbc.M207105200 [Abstract] [Full Text] [PDF]

Maureen R. Horton, Sada Boodoo, and Jonathan D. Powell: NF- $kappa$ B Activation Mediates the Cross-talk between Extracellular Matrix and Interferon- $gamma$ (IFN- $gamma$ ) Leading to Enhanced Monokine Induced by IFN- $gamma$ (MIG) Expression in Macrophages
J. Biol. Chem. 2002 277: 43757-43762. First Published on September 10, 2002; doi:10.1074/jbc.M206007200 [Abstract] [Full Text] [PDF]

Fang Cheng, Katrin Mani, Jacob van den Born, Kan Ding, Mattias Belting, and Lars-Åke Fransson: Nitric Oxide-dependent Processing of Heparan Sulfate in Recycling S-Nitrosylated Glypican-1 Takes Place in Caveolin-1-containing Endosomes
J. Biol. Chem. 2002 277: 44431-44439. First Published on September 10, 2002; doi:10.1074/jbc.M205241200 [Abstract] [Full Text] [PDF]

Joanna Cichy, Robert Bals, Jan Potempa, Anne Mani, and Ellen Puré: Proteinase-mediated Release of Epithelial Cell-associated CD44. EXTRACELLULAR CD44 COMPLEXES WITH COMPONENTS OF CELLULAR MATRICES
J. Biol. Chem. 2002 277: 44440-44447. First Published on September 10, 2002; doi:10.1074/jbc.M207437200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Antoni R. Slabas, Johan T. M. Kroon, Ted P. Scheirer, John S. Gilroy, Matthew Hayman, David W. Rice, Andy P. Turnbull, John B. Rafferty, Tony Fawcett, and William J. Simon: Squash Glycerol-3-phosphate (1)-Acyltransferase. ALTERATION OF SUBSTRATE SELECTIVITY AND IDENTIFICATION OF ARGININE AND LYSINE RESIDUES IMPORTANT IN CATALYTIC ACTIVITY
J. Biol. Chem. 2002 277: 43918-43923. First Published on August 29, 2002; doi:10.1074/jbc.M206429200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Neil Tran, Catherine Proenza, Vincenzo Macri, Fiona Petigara, Erin Sloan, Shannon Samler, and Eric A. Accili: A Conserved Domain in the NH₂ Terminus Important for Assembly and Functional Expression of Pacemaker Channels
J. Biol. Chem. 2002 277: 43588-43592. First Published on August 21, 2002; doi:10.1074/jbc.M208477200 [Abstract] [Full Text] [PDF]

Jean-Christophe Marvaud, Bradley G. Stiles, Alexandre Chenal, Daniel Gillet, Maryse Gibert, Leonard A. Smith, and Michel R. Popoff: Clostridium perfringens Iota Toxin. MAPPING OF THE Ia DOMAIN INVOLVED IN DOCKING WITH Ib AND CELLULAR INTERNALIZATION
J. Biol. Chem. 2002 277: 43659-43666. First Published on September 6, 2002; doi:10.1074/jbc.M207828200 [Abstract] [Full Text] [PDF]

Petra Scholze, Michael Freissmuth, and Harald H. Sitte: Mutations within an Intramembrane Leucine Heptad Repeat Disrupt Oligomer Formation of the Rat GABA Transporter 1
J. Biol. Chem. 2002 277: 43682-43690. First Published on September 9, 2002; doi:10.1074/jbc.M205602200 [Abstract] [Full Text] [PDF]

Viviana I. Torres and David S. Weiss: Identification of a Tyrosine in the Agonist Binding Site of the Homomeric $rho$ 1 $gamma$ -Aminobutyric Acid (GABA) Receptor That, When Mutated, Produces Spontaneous Opening
J. Biol. Chem. 2002 277: 43741-43748. First Published on September 10, 2002; doi:10.1074/jbc.M202007200 [Abstract] [Full Text] [PDF]

Tianxiang Pang, Shigeo Wakabayashi, and Munekazu Shigekawa: Expression of Calcineurin B Homologous Protein 2 Protects Serum Deprivation-induced Cell Death by Serum-independent Activation of Na⁺/H⁺ Exchanger
J. Biol. Chem. 2002 277: 43771-43777. First Published on September 10, 2002; doi:10.1074/jbc.M208313200 [Abstract] [Full Text] [PDF]

Maria Kauppi, Gerd Wohlfahrt, and Vesa M. Olkkonen: Analysis of the Munc18b-Syntaxin Binding Interface. USE OF A MUTANT Munc18b TO DISSECT THE FUNCTIONS OF SYNTAXINS 2 AND 3
J. Biol. Chem. 2002 277: 43973-43979. First Published on August 26, 2002; doi:10.1074/jbc.M208315200 [Abstract] [Full Text] [PDF]

Andrey P. Babenko and Joseph Bryan: SUR-dependent Modulation of K_ATP Channels by an N-terminal K_IR6.2 Peptide. DEFINING INTERSUBUNIT GATING INTERACTIONS
J. Biol. Chem. 2002 277: 43997-44004. First Published on September 3, 2002; doi:10.1074/jbc.M208085200 [Abstract] [Full Text] [PDF]

Guocheng He, Sarita Gupta, Ming Yi, Peter Michaely, Helen H. Hobbs, and Jonathan C. Cohen: ARH Is a Modular Adaptor Protein That Interacts with the LDL Receptor, Clathrin, and AP-2
J. Biol. Chem. 2002 277: 44044-44049. First Published on September 8, 2002; doi:10.1074/jbc.M208539200 [Abstract] [Full Text] [PDF]

Byung-Eun Kim, Kathryn Smith, Carisa K. Meagher, and Michael J. Petris: A Conditional Mutation Affecting Localization of the Menkes Disease Copper ATPase. SUPPRESSION BY COPPER SUPPLEMENTATION
J. Biol. Chem. 2002 277: 44079-44084. First Published on September 6, 2002; doi:10.1074/jbc.M208737200 [Abstract] [Full Text] [PDF]

Alicia G. Howe, Vanina Zaremberg, and Christopher R. McMaster: Cessation of Growth to Prevent Cell Death Due to Inhibition of Phosphatidylcholine Synthesis Is Impaired at 37 °C in Saccharomyces cerevisiae
J. Biol. Chem. 2002 277: 44100-44107. First Published on August 27, 2002; doi:10.1074/jbc.M206643200 [Abstract] [Full Text] [PDF]

Youyun Yang, Qun Chen, and Jian-Ting Zhang: Structural and Functional Consequences of Mutating Cysteine Residues in the Amino Terminus of Human Multidrug Resistance-associated Protein 1
J. Biol. Chem. 2002 277: 44268-44277. First Published on September 13, 2002; doi:10.1074/jbc.M207003200 [Abstract] [Full Text] [PDF]

DaoHong Lin, Hyacinth Sterling, Kenneth M. Lerea, Gerhard Giebisch, and Wen-Hui Wang: Protein Kinase C (PKC)-induced Phosphorylation of ROMK1 Is Essential for the Surface Expression of ROMK1 Channels
J. Biol. Chem. 2002 277: 44278-44284. First Published on September 6, 2002; doi:10.1074/jbc.M203702200 [Abstract] [Full Text] [PDF]

Tip W. Loo and David M. Clarke: Location of the Rhodamine-binding Site in the Human Multidrug Resistance P-glycoprotein
J. Biol. Chem. 2002 277: 44332-44338. First Published on September 9, 2002; doi:10.1074/jbc.M208433200 [Abstract] [Full Text] [PDF]

Scott E. Jarvis, Wendy Barr, Zhong-Ping Feng, Jawed Hamid, and Gerald W. Zamponi: Molecular Determinants of Syntaxin 1 Modulation of N-type Calcium Channels
J. Biol. Chem. 2002 277: 44399-44407. First Published on September 6, 2002; doi:10.1074/jbc.M206902200 [Abstract] [Full Text] [PDF]

Jooyoung Jung, Soon-Youl Lee, Sun Wook Hwang, Hawon Cho, Jieun Shin, Young-Sun Kang, Sunghoon Kim, and Uhtaek Oh: Agonist Recognition Sites in the Cytosolic Tails of Vanilloid Receptor 1
J. Biol. Chem. 2002 277: 44448-44454. First Published on September 11, 2002; doi:10.1074/jbc.M207103200 [Abstract] [Full Text] [PDF]

Shuhong Luo, David A. Scott, and Roberto Docampo: Trypanosoma cruzi H⁺-ATPase 1 (TcHA1) and 2 (TcHA2) Genes Complement Yeast Mutants Defective in H⁺ Pumps and Encode Plasma Membrane P-type H⁺-ATPases with Different Enzymatic Properties
J. Biol. Chem. 2002 277: 44497-44506. First Published on September 6, 2002; doi:10.1074/jbc.M202267200 [Abstract] [Full Text] [PDF]

Kumi Tauchi-Sato, Shintaro Ozeki, Toshiaki Houjou, Ryo Taguchi, and Toyoshi Fujimoto: The Surface of Lipid Droplets Is a Phospholipid Monolayer with a Unique Fatty Acid Composition
J. Biol. Chem. 2002 277: 44507-44512. First Published on September 6, 2002; doi:10.1074/jbc.M207712200 [Abstract] [Full Text] [PDF]

Masanori Honsho, Takanobu Hiroshige, and Yukio Fujiki: The Membrane Biogenesis Peroxin Pex16p. TOPOGENESIS AND FUNCTIONAL ROLES IN PEROXISOMAL MEMBRANE ASSEMBLY
J. Biol. Chem. 2002 277: 44513-44524. First Published on September 9, 2002; doi:10.1074/jbc.M206139200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Celia Pender, Ira D. Goldfine, Vara Prasad Manchem, Joseph L. Evans, Wayne R. Spevak, Songyuan Shi, Sandhya Rao, Sonia Bajjalieh, Betty A. Maddux, and Jack F. Youngren: Regulation of Insulin Receptor Function by a Small Molecule Insulin Receptor Activator
J. Biol. Chem. 2002 277: 43565-43571. First Published on September 3, 2002; doi:10.1074/jbc.M202426200 [Abstract] [Full Text] [PDF]

Albrecht Piiper, Ivan Dikic, Manfred P. Lutz, Jürgen Leser, Bernd Kronenberger, Robert Elez, Henning Cramer, Werner Müller-Esterl, and Stefan Zeuzem: Cyclic AMP Induces Transactivation of the Receptors for Epidermal Growth Factor and Nerve Growth Factor, Thereby Modulating Activation of MAP Kinase, Akt, and Neurite Outgrowth in PC12 Cells
J. Biol. Chem. 2002 277: 43623-43630. First Published on September 5, 2002; doi:10.1074/jbc.M203926200 [Abstract] [Full Text] [PDF]

Hong Zhang, Xiaoqing Shi, Qian-Jin Zhang, Maggie Hampong, Harry Paddon, Dewi Wahyuningsih, and Steven Pelech: Nocodazole-induced p53-dependent c-Jun N-terminal Kinase Activation Reduces Apoptosis in Human Colon Carcinoma HCT116 Cells
J. Biol. Chem. 2002 277: 43648-43658. First Published on September 6, 2002; doi:10.1074/jbc.M203214200 [Abstract] [Full Text] [PDF]

Georgina Berridge, George Dickinson, John Parrington, Antony Galione, and Sandip Patel: Solubilization of Receptors for the Novel Ca²⁺-mobilizing Messenger, Nicotinic Acid Adenine Dinucleotide Phosphate
J. Biol. Chem. 2002 277: 43717-43723. First Published on September 9, 2002; doi:10.1074/jbc.M203224200 [Abstract] [Full Text] [PDF]

Seiji Inoshita, Kohsuke Takeda, Takiko Hatai, Yoshio Terada, Makoto Sano, Junichi Hata, Akihiro Umezawa, and Hidenori Ichijo: Phosphorylation and Inactivation of Myeloid Cell Leukemia 1 by JNK in Response to Oxidative Stress
J. Biol. Chem. 2002 277: 43730-43734. First Published on September 9, 2002; doi:10.1074/jbc.M207951200 [Abstract] [Full Text] [PDF]

Joanne L. Eyles, Donald Metcalf, Michael J. Grusby, Douglas J. Hilton, and Robyn Starr: Negative Regulation of Interleukin-12 Signaling by Suppressor of Cytokine Signaling-1
J. Biol. Chem. 2002 277: 43735-43740. First Published on September 8, 2002; doi:10.1074/jbc.M208586200 [Abstract] [Full Text] [PDF]

Hong-Yo Kang, Ko-En Huang, Shiuh Young Chang, Wen-Lung Ma, Wen-Jye Lin, and Chawnshang Chang: Differential Modulation of Androgen Receptor-mediated Transactivation by Smad3 and Tumor Suppressor Smad4
J. Biol. Chem. 2002 277: 43749-43756. First Published on September 10, 2002; doi:10.1074/jbc.M205603200 [Abstract] [Full Text] [PDF]

Annamaria Biroccio, Barbara Benassi, Giuseppe Filomeni, Sarah Amodei, Sergio Marchini, Giovanna Chiorino, Giuseppe Rotilio, Gabriella Zupi, and Maria Rosa Ciriolo: Glutathione Influences c-Myc-induced Apoptosis in M14 Human Melanoma Cells
J. Biol. Chem. 2002 277: 43763-43770. First Published on September 10, 2002; doi:10.1074/jbc.M207684200 [Abstract] [Full Text] [PDF]

Jena J. Steinle, Cynthia J. Meininger, Reza Forough, Guoyao Wu, Mack H. Wu, and Harris J. Granger: Eph B4 Receptor Signaling Mediates Endothelial Cell Migration and Proliferation via the Phosphatidylinositol 3-Kinase Pathway
J. Biol. Chem. 2002 277: 43830-43835. First Published on September 13, 2002; doi:10.1074/jbc.M207221200 [Abstract] [Full Text] [PDF]

Shao-Chun Chang, Aimee L. Miller, Yucheng Feng, Susan R. Wente, and Philip W. Majerus: The Human Homolog of the Rat Inositol Phosphate Multikinase Is an Inositol 1,3,4,6-Tetrakisphosphate 5-Kinase
J. Biol. Chem. 2002 277: 43836-43843. First Published on September 9, 2002; doi:10.1074/jbc.M206134200 [Abstract] [Full Text] [PDF]

Jonathan Franca-Koh, Margaret Yeo, Elizabeth Fraser, Neville Young, and Trevor C. Dale: The Regulation of Glycogen Synthase Kinase-3 Nuclear Export by Frat/GBP
J. Biol. Chem. 2002 277: 43844-43848. First Published on September 9, 2002; doi:10.1074/jbc.M207265200 [Abstract] [Full Text] [PDF]

Marc G. Coppolino, Renee Dierckman, Joost Loijens, Richard F. Collins, Mahmoud Pouladi, Jenny Jongstra-Bilen, Alan D. Schreiber, William S. Trimble, Richard Anderson, and Sergio Grinstein: Inhibition of Phosphatidylinositol-4-phosphate 5-Kinase I $alpha$ Impairs Localized Actin Remodeling and Suppresses Phagocytosis
J. Biol. Chem. 2002 277: 43849-43857. First Published on September 9, 2002; doi:10.1074/jbc.M209046200 [Abstract] [Full Text] [PDF]

Ava L. Taylor and Sandra J. Hewett: Potassium-evoked Glutamate Release Liberates Arachidonic Acid from Cortical Neurons
J. Biol. Chem. 2002 277: 43881-43887. First Published on September 13, 2002; doi:10.1074/jbc.M205872200 [Abstract] [Full Text] [PDF]

Jeremy W. Peck, Michael Oberst, Kerrie B. Bouker, Emma Bowden, and Peter D. Burbelo: The RhoA-binding protein, Rhophilin-2, Regulates Actin Cytoskeleton Organization
J. Biol. Chem. 2002 277: 43924-43932. First Published on September 6, 2002; doi:10.1074/jbc.M203569200 [Abstract] [Full Text] [PDF]

Evelina Grantcharova, Jens Furkert, H. Peter Reusch, Hans-Willi Krell, Gisela Papsdorf, Michael Beyermann, Ralf Schülein, Walter Rosenthal, and Alexander Oksche: The Extracellular N Terminus of the Endothelin B (ET_B) Receptor Is Cleaved by a Metalloprotease in an Agonist-dependent Process
J. Biol. Chem. 2002 277: 43933-43941. First Published on September 10, 2002; doi:10.1074/jbc.M208407200 [Abstract] [Full Text] [PDF]

Sergey A. Vishnivetskiy, Joel A. Hirsch, Maria-Gabriela Velez, Yulia V. Gurevich, and Vsevolod V. Gurevich: Transition of Arrestin into the Active Receptor-binding State Requires an Extended Interdomain Hinge
J. Biol. Chem. 2002 277: 43961-43967. First Published on September 4, 2002; doi:10.1074/jbc.M206951200 [Abstract] [Full Text] [PDF]

Xinkang Wang, Lin Xu, Hugh Wang, Peter R. Young, Matthias Gaestel, and Giora Z. Feuerstein: Mitogen-activated Protein Kinase-activated Protein (MAPKAP) Kinase 2 Deficiency Protects Brain from Ischemic Injury in Mice
J. Biol. Chem. 2002 277: 43968-43972. First Published on September 4, 2002; doi:10.1074/jbc.M206837200 [Abstract] [Full Text] [PDF]

Philippe Gual, Satoshi Shigematsu, Makoto Kanzaki, Thierry Grémeaux, Teresa Gonzalez, Jeffrey E. Pessin, Yannick Le Marchand-Brustel, and Jean-François Tanti: A Crk-II/TC10 Signaling Pathway Is Required For Osmotic Shock-stimulated Glucose Transport
J. Biol. Chem. 2002 277: 43980-43986. First Published on September 4, 2002; doi:10.1074/jbc.M203042200 [Abstract] [Full Text] [PDF]

Katrin Schröder, Alexander Pulvermüller, and Klaus Peter Hofmann: Arrestin and Its Splice Variant Arr^1-370A (p⁴⁴). MECHANISM AND BIOLOGICAL ROLE OF THEIR INTERACTION WITH RHODOPSIN
J. Biol. Chem. 2002 277: 43987-43996. First Published on August 22, 2002; doi:10.1074/jbc.M206211200 [Abstract] [Full Text] [PDF]

Masumi Eto, Elizabeth Elliott, Todd D. Prickett, and David L. Brautigan: Inhibitor-2 Regulates Protein Phosphatase-1 Complexed with NimA-related Kinase to Induce Centrosome Separation
J. Biol. Chem. 2002 277: 44013-44020. First Published on September 6, 2002; doi:10.1074/jbc.M208035200 [Abstract] [Full Text] [PDF]

Monica Antenos, Robert F. Casper, and Theodore J. Brown: Interaction with Nedd8, a Ubiquitin-like Protein, Enhances the Transcriptional Activity of the Aryl Hydrocarbon Receptor
J. Biol. Chem. 2002 277: 44028-44034. First Published on September 4, 2002; doi:10.1074/jbc.M202413200 [Abstract] [Full Text] [PDF]

Morten A. Karsdal, Lykke Larsen, Michael T. Engsig, Henriette Lou, Mercedes Ferreras, André Lochter, Jean-Marie Delaissé, and Niels T. Foged: Matrix Metalloproteinase-dependent Activation of Latent Transforming Growth Factor- $beta$ Controls the Conversion of Osteoblasts into Osteocytes by Blocking Osteoblast Apoptosis
J. Biol. Chem. 2002 277: 44061-44067. First Published on September 10, 2002; doi:10.1074/jbc.M207205200 [Abstract] [Full Text] [PDF]

Takahisa Murata, Koichi Sato, Masatoshi Hori, Hiroshi Ozaki, and Hideaki Karaki: Decreased Endothelial Nitric-oxide Synthase (eNOS) Activity Resulting from Abnormal Interaction between eNOS and Its Regulatory Proteins in Hypoxia-induced Pulmonary Hypertension
J. Biol. Chem. 2002 277: 44085-44092. First Published on August 15, 2002; doi:10.1074/jbc.M205934200 [Abstract] [Full Text] [PDF]

Riad Efendiev, Guillermo A. Yudowski, Jean Zwiller, Barbara Leibiger, Adrian I. Katz, Per-Olof Berggren, Carlos H. Pedemonte, Ingo B. Leibiger, and Alejandro M. Bertorello: Relevance of Dopamine Signals Anchoring Dynamin-2 to the Plasma Membrane during Na⁺,K⁺-ATPase Endocytosis
J. Biol. Chem. 2002 277: 44108-44114. First Published on August 29, 2002; doi:10.1074/jbc.M205173200 [Abstract] [Full Text] [PDF]

Young-Joo Jang, Sheng Ma, Yasuhiko Terada, and Raymond L. Erikson: Phosphorylation of Threonine 210 and the Role of Serine 137 in the Regulation of Mammalian Polo-like Kinase
J. Biol. Chem. 2002 277: 44115-44120. First Published on August 30, 2002; doi:10.1074/jbc.M202172200 [Abstract] [Full Text] [PDF]

Kiyoshi Takayama, Guillermo García-Cardeña, Galina K. Sukhova, Jason Comander, Michael A. Gimbrone, Jr., and Peter Libby: Prostaglandin E₂ Suppresses Chemokine Production in Human Macrophages through the EP4 Receptor
J. Biol. Chem. 2002 277: 44147-44154. First Published on September 4, 2002; doi:10.1074/jbc.M204810200 [Abstract] [Full Text] [PDF]

Anja Krippner-Heidenreich, Fabian Tübing, Susanne Bryde, Sylvia Willi, Gudrun Zimmermann, and Peter Scheurich: Control of Receptor-induced Signaling Complex Formation by the Kinetics of Ligand/Receptor Interaction
J. Biol. Chem. 2002 277: 44155-44163. First Published on September 4, 2002; doi:10.1074/jbc.M207399200 [Abstract] [Full Text] [PDF]

Rocío Jorge, Natasha Zarich, José Luis Oliva, Marta Azañedo, Natalia Martínez, Xavier de la Cruz, and José M. Rojas: hSos1 Contains a New Amino-terminal Regulatory Motif with Specific Binding Affinity for Its Pleckstrin Homology Domain
J. Biol. Chem. 2002 277: 44171-44179. First Published on September 9, 2002; doi:10.1074/jbc.M204423200 [Abstract] [Full Text] [PDF]

John K. G. Crean, Darren Finlay, Madeline Murphy, Catherine Moss, Catherine Godson, Finian Martin, and Hugh R. Brady: The Role of p42/44 MAPK and Protein Kinase B in Connective Tissue Growth Factor Induced Extracellular Matrix Protein Production, Cell Migration, and Actin Cytoskeletal Rearrangement in Human Mesangial Cells
J. Biol. Chem. 2002 277: 44187-44194. First Published on September 5, 2002; doi:10.1074/jbc.M203715200 [Abstract] [Full Text] [PDF]

Rieko Katsu, Hiroshi Onogi, Kazuhiro Wada, Yasushi Kawaguchi, and Masatoshi Hagiwara: Novel SR-rich-related Protein Clasp Specifically Interacts with Inactivated Clk4 and Induces the Exon EB Inclusion of Clk
J. Biol. Chem. 2002 277: 44220-44228. First Published on August 6, 2002; doi:10.1074/jbc.M206504200 [Abstract] [Full Text] [PDF]

Christina R. Arnt, Mihnea V. Chiorean, Michael P. Heldebrant, Gregory J. Gores, and Scott H. Kaufmann: Synthetic Smac/DIABLO Peptides Enhance the Effects of Chemotherapeutic Agents by Binding XIAP and cIAP1 in Situ
J. Biol. Chem. 2002 277: 44236-44243. First Published on September 5, 2002; doi:10.1074/jbc.M207578200 [Abstract] [Full Text] [PDF]

Tsuyoshi Hirota, Toshiyuki Okano, Koichi Kokame, Hiroko Shirotani-Ikejima, Toshiyuki Miyata, and Yoshitaka Fukada: Glucose Down-regulates Per1 and Per2 mRNA Levels and Induces Circadian Gene Expression in Cultured Rat-1 Fibroblasts
J. Biol. Chem. 2002 277: 44244-44251. First Published on September 3, 2002; doi:10.1074/jbc.M206233200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Theocharis Panaretakis, Katja Pokrovskaja, Maria C. Shoshan, and Dan Grandér: Activation of Bak, Bax, and BH3-only Proteins in the Apoptotic Response to Doxorubicin
J. Biol. Chem. 2002 277: 44317-44326. First Published on August 21, 2002; doi:10.1074/jbc.M205273200 [Abstract] [Full Text] [PDF]

Irina Korichneva, Beatrice Hoyos, Ramon Chua, Ester Levi, and Ulrich Hammerling: Zinc Release from Protein Kinase C as the Common Event during Activation by Lipid Second Messenger or Reactive Oxygen
J. Biol. Chem. 2002 277: 44327-44331. First Published on September 3, 2002; doi:10.1074/jbc.M205634200 [Abstract] [Full Text] [PDF]

Allison P. Armstrong, Mark E. Tometsko, Moira Glaccum, Claire L. Sutherland, David Cosman, and William C. Dougall: A RANK/TRAF6-dependent Signal Transduction Pathway Is Essential for Osteoclast Cytoskeletal Organization and Resorptive Function
J. Biol. Chem. 2002 277: 44347-44356. First Published on August 15, 2002; doi:10.1074/jbc.M202009200 [Abstract] [Full Text] [PDF]

Ali Pedram, Mahnaz Razandi, and Ellis R. Levin: Deciphering Vascular Endothelial Cell Growth Factor/Vascular Permeability Factor Signaling to Vascular Permeability. INHIBITION BY ATRIAL NATRIURETIC PEPTIDE
J. Biol. Chem. 2002 277: 44385-44398. First Published on September 3, 2002; doi:10.1074/jbc.M202391200 [Abstract] [Full Text] [PDF]

Eun-Young Shin, Kyung-Sun Shin, Chan-Soo Lee, Kyung-Nam Woo, Song-Hua Quan, Nak-Kyun Soung, Young Gyu Kim, Choong Ik Cha, Seung-Ryul Kim, Dongeun Park, Gary M. Bokoch, and Eung-Gook Kim: Phosphorylation of p85 $beta$ PIX, a Rac/Cdc42-specific Guanine Nucleotide Exchange Factor, via the Ras/ERK/PAK2 Pathway Is Required for Basic Fibroblast Growth Factor-induced Neurite Outgrowth
J. Biol. Chem. 2002 277: 44417-44430. First Published on September 10, 2002; doi:10.1074/jbc.M203754200 [Abstract] [Full Text] [PDF]

Takeyuki Nishi, Noriaki Shimizu, Masaki Hiramoto, Iwao Sato, Yuki Yamaguchi, Makoto Hasegawa, Shin Aizawa, Hirotoshi Tanaka, Kohsuke Kataoka, Hajime Watanabe, and Hiroshi Handa: Spatial Redox Regulation of a Critical Cysteine Residue of NF- $kappa$ B in Vivo
J. Biol. Chem. 2002 277: 44548-44556. First Published on September 3, 2002; doi:10.1074/jbc.M202970200 [Abstract] [Full Text] [PDF]

Graciela Piwien-Pilipuk, Ormond MacDougald, and Jessica Schwartz: Dual Regulation of Phosphorylation and Dephosphorylation of C/EBP $beta$ Modulate Its Transcriptional Activation and DNA Binding in Response to Growth Hormone
J. Biol. Chem. 2002 277: 44557-44565. First Published on September 3, 2002; doi:10.1074/jbc.M206886200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Sue Shackleton, Isabelle Hamer, Michelangelo Foti, Nicole Zumwald, Christine Maeder, and Jean-Louis Carpentier: Role of Two Dileucine-like Motifs in Insulin Receptor Anchoring to Microvilli
J. Biol. Chem. 2002 277: 43631-43637. First Published on September 5, 2002; doi:10.1074/jbc.M204036200 [Abstract] [Full Text] [PDF]

Concepción Almoguera, Anabel Rojas, Juan Díaz-Martín, Pilar Prieto-Dapena, Raúl Carranco, and Juan Jordano: A Seed-specific Heat-shock Transcription Factor Involved in Developmental Regulation during Embryogenesis in Sunflower
J. Biol. Chem. 2002 277: 43866-43872. First Published on September 12, 2002; doi:10.1074/jbc.M207330200 [Abstract] [Full Text] [PDF]

Mei Zhang, Shouhong Xuan, Mary L. Bouxsein, Dietrich von Stechow, Nagako Akeno, Marie Claude Faugere, Hartmut Malluche, Guisheng Zhao, Clifford J. Rosen, Argiris Efstratiadis, and Thomas L. Clemens: Osteoblast-specific Knockout of the Insulin-like Growth Factor (IGF) Receptor Gene Reveals an Essential Role of IGF Signaling in Bone Matrix Mineralization
J. Biol. Chem. 2002 277: 44005-44012. First Published on September 4, 2002; doi:10.1074/jbc.M208265200 [Abstract] [Full Text] [PDF]

Kazushi Sasagawa, Yuji Matsudo, Myenmo Kang, Lisa Fujimura, Yoshinori Iitsuka, Seiji Okada, Takenori Ochiai, Takeshi Tokuhisa, and Masahiko Hatano: Identification of Nd1, a Novel Murine Kelch Family Protein, Involved in Stabilization of Actin Filaments
J. Biol. Chem. 2002 277: 44140-44146. First Published on September 3, 2002; doi:10.1074/jbc.M202596200 [Abstract] [Full Text] [PDF]

Luciana A. Haddad, Nicole Smith, Mark Bowser, Yo Niida, Vanishree Murthy, Charo Gonzalez-Agosti, and Vijaya Ramesh: The TSC1 Tumor Suppressor Hamartin Interacts with Neurofilament-L and Possibly Functions as a Novel Integrator of the Neuronal Cytoskeleton
J. Biol. Chem. 2002 277: 44180-44186. First Published on September 10, 2002; doi:10.1074/jbc.M207211200 [Abstract] [Full Text] [PDF]

Zhi-Liang Wu, Teresa M. O'Kane, Richard W. Scott, Mary J. Savage, and Donna Bozyczko-Coyne: Protein Tyrosine Phosphatases Are Up-regulated and Participate in Cell Death Induced by Polyglutamine Expansion
J. Biol. Chem. 2002 277: 44208-44213. First Published on September 10, 2002; doi:10.1074/jbc.M206890200 [Abstract] [Full Text] [PDF]

Jun Peng, Zhijin Wu, Yongqin Wu, Mike Hsu, Fang Feng Stevenson, Rapee Boonplueang, Suzanne K. Roffler-Tarlov, and Julie K. Andersen: Inhibition of Caspases Protects Cerebellar Granule Cells of the Weaver Mouse from Apoptosis and Improves Behavioral Phenotype
J. Biol. Chem. 2002 277: 44285-44291. First Published on September 6, 2002; doi:10.1074/jbc.M207407200 [Abstract] [Full Text] [PDF]

Xinhe Wang, Katherine Krupczak-Hollis, Yongjun Tan, Margaret B. Dennewitz, Guy R. Adami, and Robert H. Costa: Increased Hepatic Forkhead Box M1B (FoxM1B) Levels in Old-aged Mice Stimulated Liver Regeneration through Diminished p27^Kip1 Protein Levels and Increased Cdc25B Expression
J. Biol. Chem. 2002 277: 44310-44316. First Published on September 6, 2002; doi:10.1074/jbc.M207510200 [Abstract] [Full Text] [PDF]

Sharon Wald Krauss, Rebecca Heald, Gloria Lee, Wataru Nunomura, J. Aura Gimm, Narla Mohandas, and Joel Anne Chasis: Two Distinct Domains of Protein 4.1 Critical for Assembly of Functional Nuclei in Vitro
J. Biol. Chem. 2002 277: 44339-44346. First Published on August 8, 2002; doi:10.1074/jbc.M204135200 [Abstract] [Full Text] [PDF]

Xiao Tu, Priti Batta, Nathalie Innocent, Marco Prisco, Ivan Casaburi, Barbara Belletti, and Renato Baserga: Nuclear Translocation of Insulin Receptor Substrate-1 by Oncogenes And Igf-I. EFFECT ON RIBOSOMAL RNA SYNTHESIS^*
J. Biol. Chem. 2002 277: 44357-44365. First Published on August 28, 2002; doi:10.1074/jbc.M208001200 [Abstract] [Full Text] [PDF]

Yan Hu, Joseph E. Ippolito, Emily M. Garabedian, Peter A. Humphrey, and Jeffrey I. Gordon: Molecular Characterization of a Metastatic Neuroendocrine Cell Cancer Arising in the Prostates of Transgenic Mice
J. Biol. Chem. 2002 277: 44462-44474. First Published on September 11, 2002; doi:10.1074/jbc.M205784200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Additions and Corrections:

Yvonne L. Kapila, Shaohui Wang, Paul Dazin, Elizabeth Tafolla, and Marc J. Mass: The heparin-binding domain and V region of fibronectin regulate apoptosis by suppression of p53 and c-myc in human primary cells.
J. Biol. Chem. 2002 277: 44588. [Full Text] [PDF]

Nóra Nusser, Elvira Gosmanova, Yi Zheng, and Gabor Tigyi: Nerve growth factor signals through TrkA, phosphatidylinositol 3-kinase, and Rac1 to inactivate RhoA during the initiation of neuronal differentiation of PC12 cells.
J. Biol. Chem. 2002 277: 44588a. [Full Text] [PDF]

William T. Doerrler and Christian R. H. Raetz: ATPase activity of the MsbA lipid flippase of Escherichia coli.
J. Biol. Chem. 2002 277: 44588b. [Full Text] [PDF]