Accelerated Publications:

Stacy L. Springs, Virginia M. Diavolitsis, Joseph Goodhouse, and George L. McLendon

The Kinetics of Translocation of Smac/DIABLO from the Mitochondria to the Cytosol in HeLa Cells
J. Biol. Chem. 2002 277: 45715-45718. First Published on October 2, 2002; 10.1074/jbc.C200524200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Tseh-Ling Chang, Asma Naqvi, Syam P. Anand, M. Gabriela Kramer, Rajan Munshi, and Saleem A. Khan

Biochemical Characterization of the Staphylococcus aureus PcrA Helicase and Its Role in Plasmid Rolling Circle Replication
J. Biol. Chem. 2002 277: 45880-45886. First Published on September 19, 2002; 10.1074/jbc.M207383200 [Abstract] [Full Text] [PDF]  

Janice A. Lloyd, Anthony L. Forget, and Kendall L. Knight

Correlation of Biochemical Properties with the Oligomeric State of Human Rad52 Protein
J. Biol. Chem. 2002 277: 46172-46178. First Published on September 10, 2002; 10.1074/jbc.M207262200 [Abstract] [Full Text] [PDF]  

Konstantin Kiianitsa, Jachen A. Solinger, and Wolf-Dietrich Heyer

Rad54 Protein Exerts Diverse Modes of ATPase Activity on Duplex DNA Partially and Fully Covered with Rad51 Protein
J. Biol. Chem. 2002 277: 46205-46215. First Published on September 30, 2002; 10.1074/jbc.M207967200 [Abstract] [Full Text] [PDF]  

Sarah L. Donahue and Colin Campbell

A DNA Double Strand Break Repair Defect in Fanconi Anemia Fibroblasts
J. Biol. Chem. 2002 277: 46243-46247. First Published on October 1, 2002; 10.1074/jbc.M207937200 [Abstract] [Full Text] [PDF]  

Yukiko Kitagawa, Kaoru Inoue, Shigeru Sasaki, Yasuhide Hayashi, Yoshinobu Matsuo, Michael R. Lieber, Hideaki Mizoguchi, Jun Yokota, and Takashi Kohno

Prevalent Involvement of Illegitimate V(D)J Recombination in Chromosome 9p21 Deletions in Lymphoid Leukemia
J. Biol. Chem. 2002 277: 46289-46297. First Published on September 12, 2002; 10.1074/jbc.M208353200 [Abstract] [Full Text] [PDF]  

Abu Amar M. Al Mamun, Kenneth J. Marians, and M. Zafri Humayun

DNA Polymerase III from Escherichia coli Cells Expressing mutA Mistranslator tRNA Is Error-prone
J. Biol. Chem. 2002 277: 46319-46327. First Published on September 24, 2002; 10.1074/jbc.M206856200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Masahiko Goda, Yoshiteru Hashimoto, Masanori Takase, Sachio Herai, Yasuhito Iwahara, Hiroki Higashibata, and Michihiko Kobayashi

Isonitrile Hydratase from Pseudomonas putida N19-2. CLONING, SEQUENCING, GENE EXPRESSION, AND IDENTIFICATION OF ITS ACTIVE AMINO ACID RESIDUE
J. Biol. Chem. 2002 277: 45860-45865. First Published on September 18, 2002; 10.1074/jbc.M208571200 [Abstract] [Full Text] [PDF]  

Patrick S. Lin, Marie-Françoise Dubois, and Michael E. Dahmus

TFIIF-associating Carboxyl-terminal Domain Phosphatase Dephosphorylates Phosphoserines 2 and 5 of RNA Polymerase II
J. Biol. Chem. 2002 277: 45949-45956. First Published on September 25, 2002; 10.1074/jbc.M208588200 [Abstract] [Full Text] [PDF]  

Anu M. Idicula, Gregory L. Blatch, Terrance G. Cooper, and Rosemary A. Dorrington

Binding and Activation by the Zinc Cluster Transcription Factors of Saccharomyces cerevisiae. REDEFINING THE UAS_GABA AND ITS INTERACTION WITH Uga3p
J. Biol. Chem. 2002 277: 45977-45983. First Published on September 13, 2002; 10.1074/jbc.M201789200 [Abstract] [Full Text] [PDF]  

Daniel B. Hall and Kevin Struhl

The VP16 Activation Domain Interacts with Multiple Transcriptional Components as Determined by Protein-Protein Cross-linking in Vivo
J. Biol. Chem. 2002 277: 46043-46050. First Published on September 23, 2002; 10.1074/jbc.M208911200 [Abstract] [Full Text] [PDF]  

Catherine Teyssier, Dagang Chen, and Michael R. Stallcup

Requirement for Multiple Domains of the Protein Arginine Methyltransferase CARM1 in Its Transcriptional Coactivator Function
J. Biol. Chem. 2002 277: 46066-46072. First Published on September 25, 2002; 10.1074/jbc.M207623200 [Abstract] [Full Text] [PDF]  

Delwin J. Long, II, Karim Iskander, Amos Gaikwad, Meral Arin, Dennis R. Roop, Richard Knox, Roberto Barrios, and Anil K. Jaiswal

Disruption of Dihydronicotinamide Riboside:Quinone Oxidoreductase 2 (NQO2) Leads to Myeloid Hyperplasia of Bone Marrow and Decreased Sensitivity to Menadione Toxicity
J. Biol. Chem. 2002 277: 46131-46139. First Published on September 25, 2002; 10.1074/jbc.M208675200 [Abstract] [Full Text] [PDF]  

Ricardo V. Ullán, Javier Casqueiro, Oscar Bañuelos, Francisco J. Fernández, Santiago Gutiérrez, and Juan F. Martín

A Novel Epimerization System in Fungal Secondary Metabolism Involved in the Conversion of Isopenicillin N into Penicillin N in Acremonium chrysogenum
J. Biol. Chem. 2002 277: 46216-46225. First Published on September 11, 2002; 10.1074/jbc.M207482200 [Abstract] [Full Text] [PDF]  

Li Zhang, Masako Hosoi, Misa Fukuzawa, Hui Sun, Robert R. Rawlings, and Forrest F. Weight

Distinct Molecular Basis for Differential Sensitivity of the Serotonin Type 3A Receptor to Ethanol in the Absence and Presence of Agonist
J. Biol. Chem. 2002 277: 46256-46264. First Published on October 3, 2002; 10.1074/jbc.M207683200 [Abstract] [Full Text] [PDF]  

Ruey-Bing Yang, Chi Kin Domingos Ng, Scott M. Wasserman, Steven D. Colman, Suresh Shenoy, Fuad Mehraban, László G. Kömüves, James E. Tomlinson, and James N. Topper

Identification of a Novel Family of Cell-surface Proteins Expressed in Human Vascular Endothelium
J. Biol. Chem. 2002 277: 46364-46373. First Published on September 21, 2002; 10.1074/jbc.M207410200 [Abstract] [Full Text] [PDF]  

Anand Desai, Dorothy Turetsky, Kuzhalini Vasudevan, and Andres Buonanno

Analysis of Transcriptional Regulatory Sequences of the N-Methyl-D-aspartate Receptor 2A Subunit Gene in Cultured Cortical Neurons and Transgenic Mice
J. Biol. Chem. 2002 277: 46374-46384. First Published on September 27, 2002; 10.1074/jbc.M203032200 [Abstract] [Full Text] [PDF]  

Benoit St-Pierre, Grace Flock, Eldad Zacksenhaus, and Sean E. Egan

Stra13 Homodimers Repress Transcription through Class B E-box Elements
J. Biol. Chem. 2002 277: 46544-46551. First Published on September 23, 2002; 10.1074/jbc.M111652200 [Abstract] [Full Text] [PDF]  

Sangita Phadtare, Sanjay Tyagi, Masayori Inouye, and Konstantin Severinov

Three Amino Acids in Escherichia coli CspE Surface-exposed Aromatic Patch Are Critical for Nucleic Acid Melting Activity Leading to Transcription Antitermination and Cold Acclimation of Cells
J. Biol. Chem. 2002 277: 46706-46711. First Published on September 24, 2002; 10.1074/jbc.M208118200 [Abstract] [Full Text] [PDF]  

David Piluso, Patricia Bilan, and John P. Capone

Host Cell Factor-1 Interacts with and Antagonizes Transactivation by the Cell Cycle Regulatory Factor Miz-1
J. Biol. Chem. 2002 277: 46799-46808. First Published on September 19, 2002; 10.1074/jbc.M206226200 [Abstract] [Full Text] [PDF]  

Bimal K. Ray, Ryan Murphy, Papiya Ray, and Alpana Ray

SAF-2, a Splice Variant of SAF-1, Acts as a Negative Regulator of Transcription
J. Biol. Chem. 2002 277: 46822-46830. First Published on September 20, 2002; 10.1074/jbc.M206299200 [Abstract] [Full Text] [PDF]  

Zhi Y. Chen, Jue-Lon Shie, and Chi-Chuan Tseng

Gut-enriched Krüppel-like Factor Represses Ornithine Decarboxylase Gene Expression and Functions as Checkpoint Regulator in Colonic Cancer Cells
J. Biol. Chem. 2002 277: 46831-46839. First Published on September 23, 2002; 10.1074/jbc.M204816200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Arlette Moncion, Nhu Traï Truong, Alessio Garrone, Philippe Beaune, Robert Barouki, and Isabelle de Waziers

Identification of a 16-Nucleotide Sequence That Mediates Post-transcriptional Regulation of Rat CYP2E1 by Insulin
J. Biol. Chem. 2002 277: 45904-45910. First Published on September 20, 2002; 10.1074/jbc.M207841200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Leslie A. Nangle, Valérie de Crécy Lagard, Volker Döring, and Paul Schimmel

Genetic Code Ambiguity. CELL VIABILITY RELATED TO SEVERITY OF EDITING DEFECTS IN MUTANT tRNA SYNTHETASES^*
J. Biol. Chem. 2002 277: 45729-45733. First Published on September 18, 2002; 10.1074/jbc.M208093200 [Abstract] [Full Text] [PDF]  

Karin Röttgers, Nicole Zufall, Bernard Guiard, and Wolfgang Voos

The ClpB Homolog Hsp78 Is Required for the Efficient Degradation of Proteins in the Mitochondrial Matrix
J. Biol. Chem. 2002 277: 45829-45837. First Published on September 16, 2002; 10.1074/jbc.M207152200 [Abstract] [Full Text] [PDF]  

Hongfei Ge, Lu Huang, Tiffany Pourbahrami, and Cai Li

Generation of Soluble Leptin Receptor by Ectodomain Shedding of Membrane-spanning Receptors in Vitro and in Vivo
J. Biol. Chem. 2002 277: 45898-45903. First Published on September 20, 2002; 10.1074/jbc.M205825200 [Abstract] [Full Text] [PDF]  

Barbara Colombo, Renato Longhi, Chiara Marinzi, Fulvio Magni, Angela Cattaneo, Seung Hyun Yoo, Flavio Curnis, and Angelo Corti

Cleavage of Chromogranin A N-terminal Domain by Plasmin Provides a New Mechanism for Regulating Cell Adhesion
J. Biol. Chem. 2002 277: 45911-45919. First Published on September 23, 2002; 10.1074/jbc.M202637200 [Abstract] [Full Text] [PDF]  

Simon Alberti, Jens Demand, Claudia Esser, Niels Emmerich, Hansjörg Schild, and Jörg Höhfeld

Ubiquitylation of BAG-1 Suggests a Novel Regulatory Mechanism during the Sorting of Chaperone Substrates to the Proteasome
J. Biol. Chem. 2002 277: 45920-45927. First Published on September 23, 2002; 10.1074/jbc.M204196200 [Abstract] [Full Text] [PDF]  

Hui Chen, Alasdair MacDonald, and Philip Coffino

Structural Elements of Antizymes 1 and 2 Are Required for Proteasomal Degradation of Ornithine Decarboxylase
J. Biol. Chem. 2002 277: 45957-45961. First Published on September 30, 2002; 10.1074/jbc.M206799200 [Abstract] [Full Text] [PDF]  

Joo Weon Lim, Hyeyoung Kim, and Kyung Hwan Kim

Expression of Ku70 and Ku80 Mediated by NF-B and Cyclooxygenase-2 Is Related to Proliferation of Human Gastric Cancer Cells
J. Biol. Chem. 2002 277: 46093-46100. First Published on September 24, 2002; 10.1074/jbc.M206603200 [Abstract] [Full Text] [PDF]  

Asok Banerjee

Coordination of Posttranslational Modifications of Bovine Brain -Tubulin. POLYGLYCYLATION OF 2 TUBULIN
J. Biol. Chem. 2002 277: 46140-46144. First Published on September 27, 2002; 10.1074/jbc.M208065200 [Abstract] [Full Text] [PDF]  

Kathryn J. MacLeod, Rhonda D. Husain, Douglas A. Gage, and Kyunghye Ahn

Constitutive Phosphorylation of Human Endothelin-converting Enzyme-1 Isoforms
J. Biol. Chem. 2002 277: 46355-46363. First Published on September 18, 2002; 10.1074/jbc.M207972200 [Abstract] [Full Text] [PDF]  

Suzana Anjos, Audrey Nguyen, Houria Ounissi-Benkalha, Marie-Catherine Tessier, and Constantin Polychronakos

A Common Autoimmunity Predisposing Signal Peptide Variant of the Cytotoxic T-lymphocyte Antigen 4 Results in Inefficient Glycosylation of the Susceptibility Allele
J. Biol. Chem. 2002 277: 46478-46486. First Published on September 19, 2002; 10.1074/jbc.M206894200 [Abstract] [Full Text] [PDF]  

Valery Krasnoperov, Yun Lu, Leonid Buryanovsky, Thomas A. Neubert, Konstantin Ichtchenko, and Alexander G. Petrenko

Post-translational Proteolytic Processing of the Calcium-independent Receptor of -Latrotoxin (CIRL), a Natural Chimera of the Cell Adhesion Protein and the G Protein-coupled Receptor. ROLE OF THE G PROTEIN-COUPLED RECEPTOR PROTEOLYSIS SITE (GPS) MOTIF
J. Biol. Chem. 2002 277: 46518-46526. First Published on September 20, 2002; 10.1074/jbc.M206415200 [Abstract] [Full Text] [PDF]  

Masahide Tojo, Kazuhito Matsuzaki, Takeshi Minami, Yoshiomi Honda, Hideyo Yasuda, Tsutomu Chiba, Hideyuki Saya, Yoshiaki Fujii-Kuriyama, and Mitsuyoshi Nakao

The Aryl Hydrocarbon Receptor Nuclear Transporter Is Modulated by the SUMO-1 Conjugation System
J. Biol. Chem. 2002 277: 46576-46585. First Published on September 26, 2002; 10.1074/jbc.M205987200 [Abstract] [Full Text] [PDF]  

Nathan E. Hellman, Satoshi Kono, Grazia M. Mancini, A. J. Hoogeboom, G. J. de Jong, and Jonathan D. Gitlin

Mechanisms of Copper Incorporation into Human Ceruloplasmin
J. Biol. Chem. 2002 277: 46632-46638. First Published on September 25, 2002; 10.1074/jbc.M206246200 [Abstract] [Full Text] [PDF]  

Fusheng Guo, Michael R. Maurizi, Lothar Esser, and Di Xia

Crystal Structure of ClpA, an Hsp100 Chaperone and Regulator of ClpAP Protease
J. Biol. Chem. 2002 277: 46743-46752. First Published on August 29, 2002; 10.1074/jbc.M207796200 [Abstract] [Full Text] [PDF]  

Fusheng Guo, Lothar Esser, Satyendra K. Singh, Michael R. Maurizi, and Di Xia

Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA⁺ Chaperone, ClpA
J. Biol. Chem. 2002 277: 46753-46762. First Published on September 15, 2002; 10.1074/jbc.M208104200 [Abstract] [Full Text] [PDF]  

Genomics Proteomics and Bioinformatics:

Kuo-Chen Chou and Yu-Dong Cai

Using Functional Domain Composition and Support Vector Machines for Prediction of Protein Subcellular Location
J. Biol. Chem. 2002 277: 45765-45769. First Published on August 16, 2002; 10.1074/jbc.M204161200 [Abstract] [Full Text] [PDF]  

Jürgen Harder and Jens-Michael Schröder

RNase 7, a Novel Innate Immune Defense Antimicrobial Protein of Healthy Human Skin
J. Biol. Chem. 2002 277: 46779-46784. First Published on September 18, 2002; 10.1074/jbc.M207587200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Joseph G. Joyce, William M. Hurni, Michael J. Bogusky, Victor M. Garsky, Xiaoping Liang, Michael P. Citron, Renee C. Danzeisen, Michael D. Miller, John W. Shiver, and Paul M. Keller

Enhancement of -Helicity in the HIV-1 Inhibitory Peptide DP178 Leads to an Increased Affinity for Human Monoclonal Antibody 2F5 but Does Not Elicit Neutralizing Responses in Vitro. IMPLICATIONS FOR VACCINE DESIGN
J. Biol. Chem. 2002 277: 45811-45820. First Published on September 16, 2002; 10.1074/jbc.M205862200 [Abstract] [Full Text] [PDF]  

Saloni Yatin Pasta, Bakthisaran Raman, Tangirala Ramakrishna, and Ch. Mohan Rao

Role of the C-terminal Extensions of -Crystallins. SWAPPING THE C-TERMINAL EXTENSION OF A-CRYSTALLIN TO B-CRYSTALLIN RESULTS IN ENHANCED CHAPERONE ACTIVITY
J. Biol. Chem. 2002 277: 45821-45828. First Published on September 15, 2002; 10.1074/jbc.M206499200 [Abstract] [Full Text] [PDF]  

Ivana Sirangelo, Clorinda Malmo, Mariateresa Casillo, Antonio Mezzogiorno, Michele Papa, and Gaetano Irace

Tryptophanyl Substitutions in Apomyoglobin Determine Protein Aggregation and Amyloid-like Fibril Formation at Physiological pH
J. Biol. Chem. 2002 277: 45887-45891. First Published on September 19, 2002; 10.1074/jbc.M207659200 [Abstract] [Full Text] [PDF]  

William P. Sullivan, Barbara A. L. Owen, and David O. Toft

The Influence of ATP and p23 on the Conformation of hsp90
J. Biol. Chem. 2002 277: 45942-45948. First Published on September 24, 2002; 10.1074/jbc.M207754200 [Abstract] [Full Text] [PDF]  

M. S. R. Sastry, Konstantin Korotkov, Yan Brodsky, and François Baneyx

Hsp31, the Escherichia coli yedU Gene Product, Is a Molecular Chaperone Whose Activity Is Inhibited by ATP at High Temperatures
J. Biol. Chem. 2002 277: 46026-46034. First Published on September 15, 2002; 10.1074/jbc.M205800200 [Abstract] [Full Text] [PDF]  

Salvino D'Amico, Charles Gerday, and Georges Feller

Dual Effects of an Extra Disulfide Bond on the Activity and Stability of a Cold-adapted -Amylase
J. Biol. Chem. 2002 277: 46110-46115. First Published on September 24, 2002; 10.1074/jbc.M207253200 [Abstract] [Full Text] [PDF]  

Álvaro Martínez del Pozo, Valle Lacadena, José M. Mancheño, Nieves Olmo, Mercedes Oñaderra, and José G. Gavilanes

The Antifungal Protein AFP of Aspergillus giganteus Is an Oligonucleotide/Oligosaccharide Binding (OB) Fold-containing Protein That Produces Condensation of DNA
J. Biol. Chem. 2002 277: 46179-46183. First Published on September 25, 2002; 10.1074/jbc.M207472200 [Abstract] [Full Text] [PDF]  

Tian Xue and Ronald A. Li

An External Determinant in the S5-P Linker of the Pacemaker (HCN) Channel Identified by Sulfhydryl Modification
J. Biol. Chem. 2002 277: 46233-46242. First Published on September 25, 2002; 10.1074/jbc.M204915200 [Abstract] [Full Text] [PDF]  

Eduard V. Bocharov, Dmitry M. Korzhnev, Marcel J. J. Blommers, Tudor Arvinte, Vladislav Yu. Orekhov, Martin Billeter, and Alexander S. Arseniev

Dynamics-modulated Biological Activity of Transforming Growth Factor 3
J. Biol. Chem. 2002 277: 46273-46279. First Published on September 6, 2002; 10.1074/jbc.M206274200 [Abstract] [Full Text] [PDF] Supplemental Data  

Yael Sandowski, Nina Raver, Eugene E. Gussakovsky, Suzan Shochat, Orly Dym, Oded Livnah, Menachem Rubinstein, Radha Krishna, and Arieh Gertler

Subcloning, Expression, Purification, and Characterization of Recombinant Human Leptin-binding Domain
J. Biol. Chem. 2002 277: 46304-46309. First Published on September 10, 2002; 10.1074/jbc.M207556200 [Abstract] [Full Text] [PDF]  

Kim C. Giese and Elizabeth Vierling

Changes in Oligomerization Are Essential for the Chaperone Activity of a Small Heat Shock Protein in Vivo and in Vitro
J. Biol. Chem. 2002 277: 46310-46318. First Published on September 23, 2002; 10.1074/jbc.M208926200 [Abstract] [Full Text] [PDF]  

Hana Im, Mi-Sook Woo, Kwang Yeon Hwang, and Myeong-Hee Yu

Interactions Causing the Kinetic Trap in Serpin Protein Folding
J. Biol. Chem. 2002 277: 46347-46354. First Published on September 18, 2002; 10.1074/jbc.M207682200 [Abstract] [Full Text] [PDF]  

Ming-Hui Li, Francis Kwok, Wen-Rui Chang, Chi-Kong Lau, Ji-Ping Zhang, Samuel C. L. Lo, Tao Jiang, and Dong-Cai Liang

Crystal Structure of Brain Pyridoxal Kinase, a Novel Member of the Ribokinase Superfamily
J. Biol. Chem. 2002 277: 46385-46390. First Published on September 15, 2002; 10.1074/jbc.M208600200 [Abstract] [Full Text] [PDF]  

E. Bartholomeus Kuettner, Rolf Hilgenfeld, and Manfred S. Weiss

The Active Principle of Garlic at Atomic Resolution
J. Biol. Chem. 2002 277: 46402-46407. First Published on September 15, 2002; 10.1074/jbc.M208669200 [Abstract] [Full Text] [PDF]  

Alphonse Ignatius Arunkumar, Sampath Srisailam, Thallampuranam Krishnaswamy Suresh Kumar, Karuppanan Muthusamy Kathir, Ya-Hui Chi, Han-Min Wang, Gu-Gang Chang, Ing- Ming Chiu, and Chin Yu

Structure and Stability of an Acidic Fibroblast Growth Factor from Notophthalmus viridescens
J. Biol. Chem. 2002 277: 46424-46432. First Published on August 29, 2002; 10.1074/jbc.M207814200 [Abstract] [Full Text] [PDF] Supplemental Data  

Larry C. Anthony and Richard R. Burgess

Conformational Flexibility in ⁷⁰ Region 2 during Transcription Initiation
J. Biol. Chem. 2002 277: 46433-46441. First Published on September 30, 2002; 10.1074/jbc.M208205200 [Abstract] [Full Text] [PDF]  

Thomas Taverner, Nathan E. Hall, Richard A. J. O'Hair, and Richard J. Simpson

Characterization of an Antagonist Interleukin-6 Dimer by Stable Isotope Labeling, Cross-linking, and Mass Spectrometry
J. Biol. Chem. 2002 277: 46487-46492. First Published on September 15, 2002; 10.1074/jbc.M207370200 [Abstract] [Full Text] [PDF]  

Arnon Henn, Shu-Ping Shi, Raz Zarivach, Efrat Ben-Zeev, and Irit Sagi

The RNA Helicase DbpA Exhibits a Markedly Different Conformation in the ADP-bound State When Compared with the ATP- or RNA-Bound States
J. Biol. Chem. 2002 277: 46559-46565. First Published on September 24, 2002; 10.1074/jbc.M207438200 [Abstract] [Full Text] [PDF]  

Tatsuro Shimamura, Akiko Ibuka, Shinya Fushinobu, Takayoshi Wakagi, Masaji Ishiguro, Yoshikazu Ishii, and Hiroshi Matsuzawa

Acyl-intermediate Structures of the Extended-spectrum Class A -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin
J. Biol. Chem. 2002 277: 46601-46608. First Published on September 8, 2002; 10.1074/jbc.M207884200 [Abstract] [Full Text] [PDF]  

Baoguang Zhao, Michael J. Bower, Patrick J. McDevitt, Huizhen Zhao, Stephen T. Davis, Kyung O. Johanson, Susan M. Green, Nestor O. Concha, and Bin-Bing S. Zhou

Structural Basis for Chk1 Inhibition by UCN-01
J. Biol. Chem. 2002 277: 46609-46615. First Published on September 19, 2002; 10.1074/jbc.M201233200 [Abstract] [Full Text] [PDF]  

Hye-Yeon Kim, Yong-Seok Heo, Jin Hwan Kim, Min Hye Park, Jinho Moon, Eunmi Kim, Doyoon Kwon, Jeongmin Yoon, Dongkyu Shin, Eui-june Jeong, Sam Yong Park, Tae Gyu Lee, Young Ho Jeon, Seonggu Ro, Joong Myung Cho, and Kwang Yeon Hwang

Molecular Basis for the Local Conformational Rearrangement of Human Phosphoserine Phosphatase
J. Biol. Chem. 2002 277: 46651-46658. First Published on September 3, 2002; 10.1074/jbc.M204866200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Elena Evguenieva-Hackenberg, Emile Schiltz, and Gabriele Klug

Dehydrogenases from All Three Domains of Life Cleave RNA
J. Biol. Chem. 2002 277: 46145-46150. First Published on September 30, 2002; 10.1074/jbc.M208717200 [Abstract] [Full Text] [PDF]  

Steven J. Orcutt, Concetta Pietropaolo, and Sriram Krishnaswamy

Extended Interactions with Prothrombinase Enforce Affinity and Specificity for Its Macromolecular Substrate
J. Biol. Chem. 2002 277: 46191-46196. First Published on October 4, 2002; 10.1074/jbc.M208677200 [Abstract] [Full Text] [PDF]  

Jennifer Stamos, Mark X. Sliwkowski, and Charles Eigenbrot

Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor
J. Biol. Chem. 2002 277: 46265-46272. First Published on August 23, 2002; 10.1074/jbc.M207135200 [Abstract] [Full Text] [PDF]  

Mark T. Brown, Kevin M. McBride, Mary Lynn Baniecki, Nancy C. Reich, Gerard Marriott, and Walter F. Mangel

Actin Can Act as a Cofactor for a Viral Proteinase in the Cleavage of the Cytoskeleton
J. Biol. Chem. 2002 277: 46298-46303. First Published on August 20, 2002; 10.1074/jbc.M202988200 [Abstract] [Full Text] [PDF]  

Aihua Hu, Fei Wang, and James R. Sellers

Mutations in Human Nonmuscle Myosin IIA Found in Patients with May-Hegglin Anomaly and Fechtner Syndrome Result in Impaired Enzymatic Function
J. Biol. Chem. 2002 277: 46512-46517. First Published on September 16, 2002; 10.1074/jbc.M208506200 [Abstract] [Full Text] [PDF]  

Ioannis Zaganas, Cleanthe Spanaki, Michael Karpusas, and Andreas Plaitakis

Substitution of Ser for Arg-443 in the Regulatory Domain of Human Housekeeping (GLUD1) Glutamate Dehydrogenase Virtually Abolishes Basal Activity and Markedly Alters the Activation of the Enzyme by ADP and L-Leucine
J. Biol. Chem. 2002 277: 46552-46558. First Published on September 24, 2002; 10.1074/jbc.M208596200 [Abstract] [Full Text] [PDF]  

Yong Jie Wei, Hui Qiao Sun, Masaya Yamamoto, Pawel Wlodarski, Kaiko Kunii, Manuel Martinez, Barbara Barylko, Joseph P. Albanesi, and Helen L. Yin

Type II Phosphatidylinositol 4-Kinase Is a Cytosolic and Peripheral Membrane Protein That Is Recruited to the Plasma Membrane and Activated by Rac-GTP
J. Biol. Chem. 2002 277: 46586-46593. First Published on September 24, 2002; 10.1074/jbc.M206860200 [Abstract] [Full Text] [PDF]  

Souzan Armstrong, Susan P. Yates, and A. Rod Merrill

Insight into the Catalytic Mechanism of Pseudomonas aeruginosa Exotoxin A. STUDIES OF TOXIN INTERACTION WITH EUKARYOTIC ELONGATION FACTOR-2
J. Biol. Chem. 2002 277: 46669-46675. First Published on September 20, 2002; 10.1074/jbc.M206916200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Ahmed Bouhss, Nathalie Josseaume, Anatoly Severin, Keiko Tabei, Jean-Emmanuel Hugonnet, David Shlaes, Dominique Mengin-Lecreulx, Jean van Heijenoort, and Michel Arthur

Synthesis of the L-Alanyl-L-alanine Cross-bridge of Enterococcus faecalis Peptidoglycan
J. Biol. Chem. 2002 277: 45935-45941. First Published on September 24, 2002; 10.1074/jbc.M207449200 [Abstract] [Full Text] [PDF]  

Begoña Comín-Anduix, László G. Boros, Silvia Marin, Joan Boren, Carles Callol-Massot, Josep J. Centelles, Josep L. Torres, Neus Agell, Sara Bassilian, and Marta Cascante

Fermented Wheat Germ Extract Inhibits Glycolysis/Pentose Cycle Enzymes and Induces Apoptosis through Poly(ADP-ribose) Polymerase Activation in Jurkat T-cell Leukemia Tumor Cells
J. Biol. Chem. 2002 277: 46408-46414. First Published on September 25, 2002; 10.1074/jbc.M206150200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Shou Takashima, Shuichi Tsuji, and Masafumi Tsujimoto

Characterization of the Second Type of Human -Galactoside 2,6-Sialyltransferase (ST6Gal II), Which Sialylates Gal1,4GlcNAc Structures on Oligosaccharides Preferentially. GENOMIC ANALYSIS OF HUMAN SIALYLTRANSFERASE GENES
J. Biol. Chem. 2002 277: 45719-45728. First Published on September 15, 2002; 10.1074/jbc.M206808200 [Abstract] [Full Text] [PDF]  

Adriane R. Todeschini, Murielle F. Girard, Jean-Michel Wieruszeski, Marise P. Nunes, George A. DosReis, Lúcia Mendonça-Previato, and José O. Previato

trans-Sialidase from Trypanosoma cruzi Binds Host T-lymphocytes in a Lectin Manner
J. Biol. Chem. 2002 277: 45962-45968. First Published on September 16, 2002; 10.1074/jbc.M203185200 [Abstract] [Full Text] [PDF]  

Jung-Eun Kim, Ha-Won Jeong, Ju-Ock Nam, Byung-Heon Lee, Je-Yong Choi, Rang-Woon Park, Jae Yong Park, and In-San Kim

Identification of Motifs in the Fasciclin Domains of the Transforming Growth Factor--induced Matrix Protein ig-h3 That Interact with the v5 Integrin
J. Biol. Chem. 2002 277: 46159-46165. First Published on September 21, 2002; 10.1074/jbc.M207055200 [Abstract] [Full Text] [PDF]  

Yoshiki Miura, Tsuyoshi Takahashi, Stephanie M. Jung, and Masaaki Moroi

Analysis of the Interaction of Platelet Collagen Receptor Glycoprotein VI (GPVI) with Collagen. A DIMERIC FORM OF GPVI, BUT NOT THE MONOMERIC FORM, SHOWS AFFINITY TO FIBROUS COLLAGEN
J. Biol. Chem. 2002 277: 46197-46204. First Published on September 29, 2002; 10.1074/jbc.M204029200 [Abstract] [Full Text] [PDF]  

Yoko Nakamura, Nicola Haines, Jihua Chen, Tetsuya Okajima, Keiko Furukawa, Takeshi Urano, Pamela Stanley, Kenneth D. Irvine, and Koichi Furukawa

Identification of a Drosophila Gene Encoding Xylosylprotein 4-Galactosyltransferase That Is Essential for the Synthesis of Glycosaminoglycans and for Morphogenesis
J. Biol. Chem. 2002 277: 46280-46288. First Published on September 4, 2002; 10.1074/jbc.M203873200 [Abstract] [Full Text] [PDF]  

Hanke van der Wel, Howard R. Morris, Maria Panico, Thanai Paxton, Anne Dell, Lee Kaplan, and Christopher M. West

Molecular Cloning and Expression of a UDP-N-acetylglucosamine (GlcNAc):Hydroxyproline Polypeptide GlcNAc-transferase That Modifies Skp1 in the Cytoplasm of Dictyostelium
J. Biol. Chem. 2002 277: 46328-46337. First Published on September 19, 2002; 10.1074/jbc.M208024200 [Abstract] [Full Text] [PDF]  

Catherine M. Radcliffe, Gundo Diedrich, David J. Harvey, Raymond A. Dwek, Peter Cresswell, and Pauline M. Rudd

Identification of Specific Glycoforms of Major Histocompatibility Complex Class I Heavy Chains Suggests That Class I Peptide Loading Is an Adaptation of the Quality Control Pathway Involving Calreticulin and ERp57
J. Biol. Chem. 2002 277: 46415-46423. First Published on September 15, 2002; 10.1074/jbc.M202466200 [Abstract] [Full Text] [PDF]  

Sadahiko Iwamoto, Maki Kumada, Toyomi Kamesaki, Hiroshi Okuda, Eiji Kajii, Takeshi Inagaki, Daisuke Saikawa, Kouichi Takeuchi, Sigeo Ohkawara, Riichi Takahashi, Shoji Ueda, Seiichiro Inoue, Kazunori Tahara, Yoji Hakamata, and Eiji Kobayashi

Rat Encodes the Paralogous Gene Equivalent of the Human Histo-blood Group ABO Gene. ASSOCIATION WITH ANTIGEN EXPRESSION BY OVEREXPRESSION OF HUMAN ABO TRANSFERASE
J. Biol. Chem. 2002 277: 46463-46469. First Published on September 16, 2002; 10.1074/jbc.M206439200 [Abstract] [Full Text] [PDF]  

Hanke van der Wel, Suzanne Z. Fisher, and Christopher M. West

A Bifunctional Diglycosyltransferase Forms the Fuc1,2Gal1,3-Disaccharide on Skp1 in the Cytoplasm of Dictyostelium
J. Biol. Chem. 2002 277: 46527-46534. First Published on September 18, 2002; 10.1074/jbc.M208824200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Zhunan Xia, Allan D. Sniderman, and Katherine Cianflone

Acylation-stimulating Protein (ASP) Deficiency Induces Obesity Resistance and Increased Energy Expenditure in ob/ob Mice
J. Biol. Chem. 2002 277: 45874-45879. First Published on September 19, 2002; 10.1074/jbc.M207281200 [Abstract] [Full Text] [PDF]  

Aya Itoh, Anthony L. Schilmiller, Bonnie C. McCaig, and Gregg A. Howe

Identification of a Jasmonate-regulated Allene Oxide Synthase That Metabolizes 9-Hydroperoxides of Linoleic and Linolenic Acids
J. Biol. Chem. 2002 277: 46051-46058. First Published on September 25, 2002; 10.1074/jbc.M207234200 [Abstract] [Full Text] [PDF]  

Renliang Zhang, Marie-Luise Brennan, Zhongzhou Shen, Jennifer C. MacPherson, Dave Schmitt, Cheryl E. Molenda, and Stanley L. Hazen

Myeloperoxidase Functions as a Major Enzymatic Catalyst for Initiation of Lipid Peroxidation at Sites of Inflammation
J. Biol. Chem. 2002 277: 46116-46122. First Published on September 30, 2002; 10.1074/jbc.M209124200 [Abstract] [Full Text] [PDF]  

Yasuo Okamoto, Silvia Vaena de Avalos, and Yusuf A. Hannun

Structural Requirements for Selective Binding of ISC1 to Anionic Phospholipids
J. Biol. Chem. 2002 277: 46470-46477. First Published on September 18, 2002; 10.1074/jbc.M207779200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Bakhrom K. Berdiev, Jiazeng Xia, Biljana Jovov, James M. Markert, Timothy B. Mapstone, G. Yancey Gillespie, Catherine M. Fuller, James K. Bubien, and Dale J. Benos

Protein Kinase C Isoform Antagonism Controls BNaC2 (ASIC1) Function
J. Biol. Chem. 2002 277: 45734-45740. First Published on September 19, 2002; 10.1074/jbc.M208995200 [Abstract] [Full Text] [PDF]  

Avtandil Kalandadze, Ying Wu, and Michael B. Robinson

Protein Kinase C Activation Decreases Cell Surface Expression of the GLT-1 Subtype of Glutamate Transporter. REQUIREMENT OF A CARBOXYL-TERMINAL DOMAIN AND PARTIAL DEPENDENCE ON SERINE 486
J. Biol. Chem. 2002 277: 45741-45750. First Published on September 24, 2002; 10.1074/jbc.M203771200 [Abstract] [Full Text] [PDF]  

Sabine M. W. van Rossenberg, Karen M. Sliedregt-Bol, Nico J. Meeuwenoord, Theo J. C. van Berkel, Jacques H. van Boom, Gijs A. van der Marel, and Erik A. L. Biessen

Targeted Lysosome Disruptive Elements for Improvement of Parenchymal Liver Cell-specific Gene Delivery
J. Biol. Chem. 2002 277: 45803-45810. First Published on September 16, 2002; 10.1074/jbc.M203510200 [Abstract] [Full Text] [PDF]  

Nathalie Roudier, Pierre Ripoche, Pierre Gane, Pierre Yves Le Pennec, Geoff Daniels, Jean-Pierre Cartron, and Pascal Bailly

AQP3 Deficiency in Humans and the Molecular Basis of a Novel Blood Group System, GIL
J. Biol. Chem. 2002 277: 45854-45859. First Published on September 17, 2002; 10.1074/jbc.M208999200 [Abstract] [Full Text] [PDF]  

Mauro Cataldi, Edward Perez-Reyes, and Richard W. Tsien

Differences in Apparent Pore Sizes of Low and High Voltage-activated Ca²⁺ Channels
J. Biol. Chem. 2002 277: 45969-45976. First Published on August 26, 2002; 10.1074/jbc.M203922200 [Abstract] [Full Text] [PDF]  

Sabine W. Baumann, Roland Baur, and Erwin Sigel

Forced Subunit Assembly in ₁₂₂ GABA_A Receptors. INSIGHT INTO THE ABSOLUTE ARRANGEMENT
J. Biol. Chem. 2002 277: 46020-46025. First Published on September 24, 2002; 10.1074/jbc.M207663200 [Abstract] [Full Text] [PDF]  

Jeanine de Keyzer, Chris van der Does, and Arnold J. M. Driessen

Kinetic Analysis of the Translocation of Fluorescent Precursor Proteins into Escherichia coli Membrane Vesicles
J. Biol. Chem. 2002 277: 46059-46065. First Published on September 10, 2002; 10.1074/jbc.M208449200 [Abstract] [Full Text] [PDF]  

Jinzhe Mao, Lilly Li, Maurine McManus, Jianping Wu, Ningren Cui, and Chun Jiang

Molecular Determinants for Activation of G-protein-coupled Inward Rectifier K⁺ (GIRK) Channels by Extracellular Acidosis
J. Biol. Chem. 2002 277: 46166-46171. First Published on October 1, 2002; 10.1074/jbc.M205438200 [Abstract] [Full Text] [PDF]  

Itsaso Hormaeche, Itziar Alkorta, Fernando Moro, José M. Valpuesta, Félix M. Goñi, and Fernando de la Cruz

Purification and Properties of TrwB, a Hexameric, ATP-binding Integral Membrane Protein Essential for R388 Plasmid Conjugation
J. Biol. Chem. 2002 277: 46456-46462. First Published on September 18, 2002; 10.1074/jbc.M207250200 [Abstract] [Full Text] [PDF]  

Nicole Jenne, Karolin Frey, Britta Brügger, and Felix T. Wieland

Oligomeric State and Stoichiometry of p24 Proteins in the Early Secretory Pathway
J. Biol. Chem. 2002 277: 46504-46511. First Published on September 16, 2002; 10.1074/jbc.M206989200 [Abstract] [Full Text] [PDF] Supplemental Data  

Mariko Hara, Tonghui Ma, and A. S. Verkman

Selectively Reduced Glycerol in Skin of Aquaporin-3-deficient Mice May Account for Impaired Skin Hydration, Elasticity, and Barrier Recovery
J. Biol. Chem. 2002 277: 46616-46621. First Published on September 21, 2002; 10.1074/jbc.M209003200 [Abstract] [Full Text] [PDF]  

Daniel R. Bellemare, Lance Shaner, Kevin A. Morano, Jude Beaudoin, Réjean Langlois, and Simon Labbé

Ctr6, a Vacuolar Membrane Copper Transporter in Schizosaccharomyces pombe
J. Biol. Chem. 2002 277: 46676-46686. First Published on September 18, 2002; 10.1074/jbc.M206444200 [Abstract] [Full Text] [PDF]  

Zheng Liu, Jing Zhang, Pin Li, S. R. Wayne Chen, and Terence Wagenknecht

Three-dimensional Reconstruction of the Recombinant Type 2 Ryanodine Receptor and Localization of Its Divergent Region 1
J. Biol. Chem. 2002 277: 46712-46719. First Published on September 24, 2002; 10.1074/jbc.M208124200 [Abstract] [Full Text] [PDF]  

Michael J. Petris, Ilia Voskoboinik, Michael Cater, Kathryn Smith, Byung-Eun Kim, Roxana M. Llanos, Daniel Strausak, James Camakaris, and Julian F. B. Mercer

Copper-regulated Trafficking of the Menkes Disease Copper ATPase Is Associated with Formation of a Phosphorylated Catalytic Intermediate
J. Biol. Chem. 2002 277: 46736-46742. First Published on September 12, 2002; 10.1074/jbc.M208864200 [Abstract] [Full Text] [PDF]  

Robert M. Cleverley and Lila M. Gierasch

Mapping the Signal Sequence-binding Site on SRP Reveals a Significant Role for the NG Domain
J. Biol. Chem. 2002 277: 46763-46768. First Published on September 19, 2002; 10.1074/jbc.M207427200 [Abstract] [Full Text] [PDF]  

Robert G. Parton, Juan Carlos Molero, Matthias Floetenmeyer, Kathryn M. Green, and David E. James

Characterization of a Distinct Plasma Membrane Macrodomain in Differentiated Adipocytes
J. Biol. Chem. 2002 277: 46769-46778. First Published on September 27, 2002; 10.1074/jbc.M205683200 [Abstract] [Full Text] [PDF]  

Shun-ichi Wada, Masakazu Niimi, Kyoko Niimi, Ann R. Holmes, Brian C. Monk, Richard D. Cannon, and Yoshimasa Uehara

Candida glabrata ATP-binding Cassette Transporters Cdr1p and Pdh1p Expressed in a Saccharomyces cerevisiae Strain Deficient in Membrane Transporters Show Phosphorylation-dependent Pumping Properties
J. Biol. Chem. 2002 277: 46809-46821. First Published on September 19, 2002; 10.1074/jbc.M207817200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

David P. Aiello, Lianwu Fu, Attila Miseta, and David M. Bedwell

Intracellular Glucose 1-Phosphate and Glucose 6-Phosphate Levels Modulate Ca²⁺ Homeostasis in Saccharomyces cerevisiae
J. Biol. Chem. 2002 277: 45751-45758. First Published on September 25, 2002; 10.1074/jbc.M208748200 [Abstract] [Full Text] [PDF]  

Young Sun, Monita P. Wilson, and Philip W. Majerus

Inositol 1,3,4-Trisphosphate 5/6-Kinase Associates with the COP9 Signalosome by Binding to CSN1
J. Biol. Chem. 2002 277: 45759-45764. First Published on September 24, 2002; 10.1074/jbc.M208709200 [Abstract] [Full Text] [PDF]  

Meng-Ru Shen, Cheng-Yang Chou, Keng-Fu Hsu, and J. Clive Ellory

Osmotic Shrinkage of Human Cervical Cancer Cells Induces an Extracellular Cl-dependent Nonselective Cation Channel, Which Requires p38 MAPK
J. Biol. Chem. 2002 277: 45776-45784. First Published on September 10, 2002; 10.1074/jbc.M207993200 [Abstract] [Full Text] [PDF]  

Ewen D. Gallagher, Shuichan Xu, Carolyn Moomaw, Clive A. Slaughter, and Melanie H. Cobb

Binding of JNK/SAPK to MEKK1 Is Regulated by Phosphorylation
J. Biol. Chem. 2002 277: 45785-45792. First Published on September 12, 2002; 10.1074/jbc.M207702200 [Abstract] [Full Text] [PDF]  

Jörg Hamm, Dario R. Alessi, and Ricardo M. Biondi

Bi-functional, Substrate Mimicking RNA Inhibits MSK1-mediated cAMP-response Element-binding Protein Phosphorylation and Reveals Magnesium Ion-dependent Conformational Changes of the Kinase
J. Biol. Chem. 2002 277: 45793-45802. First Published on September 13, 2002; 10.1074/jbc.M205072200 [Abstract] [Full Text] [PDF]  

Olivier Dormond, Manuela Bezzi, Agnese Mariotti, and Curzio Rüegg

Prostaglandin E₂ Promotes Integrin _V3-dependent Endothelial Cell Adhesion, Rac-activation, and Spreading through cAMP/PKA-dependent Signaling
J. Biol. Chem. 2002 277: 45838-45846. First Published on September 16, 2002; 10.1074/jbc.M209213200 [Abstract] [Full Text] [PDF]  

Wolfgang Holnthoner, Manuela Pillinger, Marion Gröger, Klaus Wolff, Anthony W. Ashton, Chris Albanese, Peter Neumeister, Richard G. Pestell, and Peter Petzelbauer

Fibroblast Growth Factor-2 Induces Lef/Tcf-dependent Transcription in Human Endothelial Cells
J. Biol. Chem. 2002 277: 45847-45853. First Published on September 15, 2002; 10.1074/jbc.M209354200 [Abstract] [Full Text] [PDF]  

Lucinda Smith and Jeffrey B. Smith

Lack of Constitutive Activity of the Free Kinase Domain of Protein Kinase C . DEPENDENCE ON TRANSPHOSPHORYLATION OF THE ACTIVATION LOOP
J. Biol. Chem. 2002 277: 45866-45873. First Published on September 19, 2002; 10.1074/jbc.M206420200 [Abstract] [Full Text] [PDF]  

Alexander W. Krug, Claudia Schuster, Birgit Gassner, Ruth Freudinger, Sigrid Mildenberger, Jakob Troppmair, and Michael Gekle

Human Epidermal Growth Factor Receptor-1 Expression Renders Chinese Hamster Ovary Cells Sensitive to Alternative Aldosterone Signaling
J. Biol. Chem. 2002 277: 45892-45897. First Published on September 19, 2002; 10.1074/jbc.M208851200 [Abstract] [Full Text] [PDF]  

Alexey Navdaev and Kenneth J. Clemetson

Glycoprotein Ib Cross-linking/Ligation on Echicetin-coated Surfaces or Echicetin-IgM in Stirred Suspension Activates Platelets by Cytoskeleton Modulated Calcium Release
J. Biol. Chem. 2002 277: 45928-45934. First Published on September 24, 2002; 10.1074/jbc.M206129200 [Abstract] [Full Text] [PDF]  

Kalipada Pahan, Malabendu Jana, Xiaojuan Liu, Bradley S. Taylor, Charles Wood, and Susan M. Fischer

Gemfibrozil, a Lipid-lowering Drug, Inhibits the Induction of Nitric-oxide Synthase in Human Astrocytes
J. Biol. Chem. 2002 277: 45984-45991. First Published on September 18, 2002; 10.1074/jbc.M200250200 [Abstract] [Full Text] [PDF]  

Michael J. May, Ralf B. Marienfeld, and Sankar Ghosh

Characterization of the IB-kinase NEMO Binding Domain
J. Biol. Chem. 2002 277: 45992-46000. First Published on September 19, 2002; 10.1074/jbc.M206494200 [Abstract] [Full Text] [PDF]  

Patrizia Tosetti, Timothy Turner, Qiang Lü, and Kathleen Dunlap

Unique Isoform of G-interacting Protein (RGS-GAIP) Selectively Discriminates between Two G_o-mediated Pathways That Inhibit Ca²⁺ Channels
J. Biol. Chem. 2002 277: 46001-46009. First Published on September 20, 2002; 10.1074/jbc.M207874200 [Abstract] [Full Text] [PDF]  

Natalie Lavine, Nathalie Ethier, James N. Oak, Lin Pei, Fang Liu, Phan Trieu, R. Victor Rebois, Michel Bouvier, Terence E. Hébert, and Hubert H. M. Van Tol

G Protein-coupled Receptors Form Stable Complexes with Inwardly Rectifying Potassium Channels and Adenylyl Cyclase
J. Biol. Chem. 2002 277: 46010-46019. First Published on September 23, 2002; 10.1074/jbc.M205035200 [Abstract] [Full Text] [PDF]  

Jing Yang, Jie Wu, Hong Jiang, Richard Mortensen, Sandra Austin, David R. Manning, Donna Woulfe, and Lawrence F. Brass

Signaling through G_i Family Members in Platelets. REDUNDANCY AND SPECIFICITY IN THE REGULATION OF ADENYLYL CYCLASE AND OTHER EFFECTORS
J. Biol. Chem. 2002 277: 46035-46042. First Published on September 23, 2002; 10.1074/jbc.M208519200 [Abstract] [Full Text] [PDF]  

Allison-Lynn Andrews, John W. Holloway, Sarah M. Puddicombe, Stephen T. Holgate, and Donna E. Davies

Kinetic Analysis of the Interleukin-13 Receptor Complex
J. Biol. Chem. 2002 277: 46073-46078. First Published on September 26, 2002; 10.1074/jbc.M209560200 [Abstract] [Full Text] [PDF]  

Evangeline Y. Choe, Elena S. Schoenberger, Jerome E. Groopman, and In-Woo Park

HIV Nef Inhibits T Cell Migration
J. Biol. Chem. 2002 277: 46079-46084. First Published on September 26, 2002; 10.1074/jbc.M204698200 [Abstract] [Full Text] [PDF]  

Ben C. B. Ko, Amy K. M. Lam, András Kapus, Lingzhi Fan, Sookja K. Chung, and Stephen S. M. Chung

Fyn and p38 Signaling Are Both Required for Maximal Hypertonic Activation of the Osmotic Response Element-binding Protein/Tonicity-responsive Enhancer-binding Protein (OREBP/TonEBP)
J. Biol. Chem. 2002 277: 46085-46092. First Published on September 30, 2002; 10.1074/jbc.M208138200 [Abstract] [Full Text] [PDF]  

Paola Pedarzani, Dieter D'hoedt, Kevina B. Doorty, Jonathan D. F. Wadsworth, Jeremiah S. Joseph, Kandiah Jeyaseelan, R. Manjunatha Kini, S. V. Gadre, S. M. Sapatnekar, Martin Stocker, and Peter N. Strong

Tamapin, a Venom Peptide from the Indian Red Scorpion (Mesobuthus tamulus) That Targets Small Conductance Ca²⁺-activated K⁺ Channels and Afterhyperpolarization Currents in Central Neurons
J. Biol. Chem. 2002 277: 46101-46109. First Published on September 17, 2002; 10.1074/jbc.M206465200 [Abstract] [Full Text] [PDF]  

Kirill Rosen, Wen Shi, Bruno Calabretta, and Jorge Filmus

Cell Detachment Triggers p38 Mitogen-activated Protein Kinase-dependent Overexpression of Fas Ligand. A NOVEL MECHANISM OF ANOIKIS OF INTESTINAL EPITHELIAL CELLS
J. Biol. Chem. 2002 277: 46123-46130. First Published on September 27, 2002; 10.1074/jbc.M207883200 [Abstract] [Full Text] [PDF]  

Minghua Zhu, Erin Janssen, Kin Leung, and Weiguo Zhang

Molecular Cloning of a Novel Gene Encoding a Membrane-associated Adaptor Protein (LAX) in Lymphocyte Signaling
J. Biol. Chem. 2002 277: 46151-46158. First Published on September 30, 2002; 10.1074/jbc.M208946200 [Abstract] [Full Text] [PDF]  

Rochus Franzen, Doriano Fabbro, Armaz Aschrafi, Josef Pfeilschifter, and Andrea Huwiler

Nitric Oxide Induces Degradation of the Neutral Ceramidase in Rat Renal Mesangial Cells and Is Counterregulated by Protein Kinase C
J. Biol. Chem. 2002 277: 46184-46190. First Published on September 30, 2002; 10.1074/jbc.M204034200 [Abstract] [Full Text] [PDF]  

Suvi-Katri Leivonen, Andrew Chantry, Lari Häkkinen, Jiahuai Han, and Veli-Matti Kähäri

Smad3 Mediates Transforming Growth Factor--induced Collagenase-3 (Matrix Metalloproteinase-13) Expression in Human Gingival Fibroblasts. EVIDENCE FOR CROSS-TALK BETWEEN Smad3 AND p38 SIGNALING PATHWAYS
J. Biol. Chem. 2002 277: 46338-46346. First Published on September 20, 2002; 10.1074/jbc.M206535200 [Abstract] [Full Text] [PDF]  

Ghislaine Garrel, Anne Lozach, Lydia K. Bachir, Jean-Noël Laverrière, and Raymond Counis

Pituitary Adenylate Cyclase-activating Polypeptide Stimulates Nitric-oxide Synthase Type I Expression and Potentiates the cGMP Response to Gonadotropin-releasing Hormone of Rat Pituitary Gonadotrophs
J. Biol. Chem. 2002 277: 46391-46401. First Published on September 18, 2002; 10.1074/jbc.M203763200 [Abstract] [Full Text] [PDF]  

Ashok Kumar, Imran Chaudhry, Michael B. Reid, and Aladin M. Boriek

Distinct Signaling Pathways Are Activated in Response to Mechanical Stress Applied Axially and Transversely to Skeletal Muscle Fibers
J. Biol. Chem. 2002 277: 46493-46503. First Published on September 6, 2002; 10.1074/jbc.M203654200 [Abstract] [Full Text] [PDF]  

Ryan T. Terry-Lorenzo, Elizabeth Elliot, Douglas C. Weiser, Todd D. Prickett, David L. Brautigan, and Shirish Shenolikar

Neurabins Recruit Protein Phosphatase-1 and Inhibitor-2 to the Actin Cytoskeleton
J. Biol. Chem. 2002 277: 46535-46543. First Published on September 21, 2002; 10.1074/jbc.M206960200 [Abstract] [Full Text] [PDF]  

Jae J. Song, Juong G. Rhee, Mohan Suntharalingam, Susan A. Walsh, Douglas R. Spitz, and Yong J. Lee

Role of Glutaredoxin in Metabolic Oxidative Stress. GLUTAREDOXIN AS A SENSOR OF OXIDATIVE STRESS MEDIATED BY H₂O₂
J. Biol. Chem. 2002 277: 46566-46575. First Published on September 19, 2002; 10.1074/jbc.M206826200 [Abstract] [Full Text] [PDF]  

Irena Sherameti, Sudhir K. Sopory, Artan Trebicka, Thomas Pfannschmidt, and Ralf Oelmüller

Photosynthetic Electron Transport Determines Nitrate Reductase Gene Expression and Activity in Higher Plants
J. Biol. Chem. 2002 277: 46594-46600. First Published on September 18, 2002; 10.1074/jbc.M202924200 [Abstract] [Full Text] [PDF]  

Jianxin Hu, Guadalupe Reyes-Cruz, Wangzhong Chen, Kenneth A. Jacobson, and Allen M. Spiegel

Identification of Acidic Residues in the Extracellular Loops of the Seven-transmembrane Domain of the Human Ca²⁺ Receptor Critical for Response to Ca²⁺ and a Positive Allosteric Modulator
J. Biol. Chem. 2002 277: 46622-46631. First Published on September 23, 2002; 10.1074/jbc.M207100200 [Abstract] [Full Text] [PDF]  

Jing Wang, Celeste E. Kirby, and Ronald Herbst

The Tyrosine Phosphatase PRL-1 Localizes to the Endoplasmic Reticulum and the Mitotic Spindle and Is Required for Normal Mitosis
J. Biol. Chem. 2002 277: 46659-46668. First Published on September 13, 2002; 10.1074/jbc.M206407200 [Abstract] [Full Text] [PDF]  

Huogen Lu, Poonam Shah, David Ennis, Gail Shinder, Jan Sap, Hoang Le-Tien, and I. George Fantus

The Differentiation of Skeletal Muscle Cells Involves a Protein-tyrosine Phosphatase--mediated C-Src Signaling Pathway
J. Biol. Chem. 2002 277: 46687-46695. First Published on September 25, 2002; 10.1074/jbc.M209643200 [Abstract] [Full Text] [PDF]  

Serge Arnaudeau, Maud Frieden, Kimitoshi Nakamura, Cyril Castelbou, Marek Michalak, and Nicolas Demaurex

Calreticulin Differentially Modulates Calcium Uptake and Release in the Endoplasmic Reticulum and Mitochondria
J. Biol. Chem. 2002 277: 46696-46705. First Published on September 24, 2002; 10.1074/jbc.M202395200 [Abstract] [Full Text] [PDF]  

Shiu-Hwa Yeh, Chia-Ho Lin, Ching-Fen Lee, and Po-Wu Gean

A Requirement of Nuclear Factor-B Activation in Fear-potentiated Startle
J. Biol. Chem. 2002 277: 46720-46729. First Published on September 25, 2002; 10.1074/jbc.M206258200 [Abstract] [Full Text] [PDF]  

Huiyan Zeng, Dezheng Zhao, and Debabrata Mukhopadhyay

KDR Stimulates Endothelial Cell Migration through Heterotrimeric G Protein Gq/11-mediated Activation of a Small GTPase RhoA
J. Biol. Chem. 2002 277: 46791-46798. First Published on September 19, 2002; 10.1074/jbc.M206133200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Hiroshi Sakamoto, Tetsuo Mashima, Kazuo Yamamoto, and Takashi Tsuruo

Modulation of Heat-shock Protein 27 (Hsp27) Anti-apoptotic Activity by Methylglyoxal Modification
J. Biol. Chem. 2002 277: 45770-45775. First Published on September 10, 2002; 10.1074/jbc.M207485200 [Abstract] [Full Text] [PDF]  

Deepanwita Prusty, Bae-Hang Park, Kathryn E. Davis, and Stephen R. Farmer

Activation of MEK/ERK Signaling Promotes Adipogenesis by Enhancing Peroxisome Proliferator-activated Receptor (PPAR) and C/EBP Gene Expression during the Differentiation of 3T3-L1 Preadipocytes
J. Biol. Chem. 2002 277: 46226-46232. First Published on September 20, 2002; 10.1074/jbc.M207776200 [Abstract] [Full Text] [PDF]  

Shr-Jeng Leu, Stephen C.-T. Lam, and Lester F. Lau

Pro-angiogenic Activities of CYR61 (CCN1) Mediated through Integrins _v3 and ₆₁ in Human Umbilical Vein Endothelial Cells
J. Biol. Chem. 2002 277: 46248-46255. First Published on October 2, 2002; 10.1074/jbc.M209288200 [Abstract] [Full Text] [PDF]  

Brice Gaudillière, Yang Shi, and Azad Bonni

RNA Interference Reveals a Requirement for Myocyte Enhancer Factor 2A in Activity-dependent Neuronal Survival
J. Biol. Chem. 2002 277: 46442-46446. First Published on September 13, 2002; 10.1074/jbc.M206653200 [Abstract] [Full Text] [PDF]  

Quanxi Li, Jun Wang, D. Randall Armant, Milan K. Bagchi, and Indrani C. Bagchi

Calcitonin Down-regulates E-cadherin Expression in Rodent Uterine Epithelium during Implantation
J. Biol. Chem. 2002 277: 46447-46455. First Published on September 16, 2002; 10.1074/jbc.M203555200 [Abstract] [Full Text] [PDF]  

Yu-Mei Xiong, Thomas A. Haas, and Li Zhang

Identification of Functional Segments within the ₂I-domain of Integrin _M2
J. Biol. Chem. 2002 277: 46639-46644. First Published on September 24, 2002; 10.1074/jbc.M207971200 [Abstract] [Full Text] [PDF]  

Daniel Rueda, Beatriz Navarro, Alberto Martínez-Serrano, Manuel Guzmán, and Ismael Galve-Roperh

The Endocannabinoid Anandamide Inhibits Neuronal Progenitor Cell Differentiation through Attenuation of the Rap1/B-Raf/ERK Pathway
J. Biol. Chem. 2002 277: 46645-46650. First Published on September 16, 2002; 10.1074/jbc.M206590200 [Abstract] [Full Text] [PDF]  

David Karnak, Seonok Lee, and Ben Margolis

Identification of Multiple Binding Partners for the Amino-terminal Domain of Synapse-associated Protein 97
J. Biol. Chem. 2002 277: 46730-46735. First Published on September 25, 2002; 10.1074/jbc.M208781200 [Abstract] [Full Text] [PDF]  

Ognian C. Ikonomov, Diego Sbrissa, Tamotsu Yoshimori, Timothy L. Cover, and Assia Shisheva

PIKfyve Kinase and SKD1 AAA ATPase Define Distinct Endocytic Compartments. ONLY PIKfyve EXPRESSION INHIBITS THE CELL-VACUOLATING ACTIVITY OF HELICOBACTER PYLORI VacA TOXIN
J. Biol. Chem. 2002 277: 46785-46790. First Published on September 3, 2002; 10.1074/jbc.M208068200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Christophe Grundschober, Maria Luisa Malosio, Laura Astolfi, Tiziana Giordano, Patrick Nef, and Jacopo Meldolesi

Neurosecretion competence. A comprehensive gene expression program identified in PC12 cells.
J. Biol. Chem. 2002 277: 46840. [Full Text] [PDF]  

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