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Table of Contents: Feb 1 2002; 277 (5)   [Index by Author]  [Cover Figure and Caption]
       Minireviews
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Genomics Proteomics and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Minireviews:

Guri Tzivion and Joseph Avruch
14-3-3 Proteins: Active Cofactors in Cellular Regulation by Serine/Threonine Phosphorylation
J. Biol. Chem. 2002 277: 3061-3064. First Published on November 14, 2001; 10.1074/jbc.R100059200 [Full Text] [PDF]  


Accelerated Publications:

Armin Neininger, Dimitris Kontoyiannis, Alexey Kotlyarov, Reinhard Winzen, Rolf Eckert, Hans-Dieter Volk, Helmut Holtmann, George Kollias, and Matthias Gaestel
MK2 Targets AU-rich Elements and Regulates Biosynthesis of Tumor Necrosis Factor and Interleukin-6 Independently at Different Post-transcriptional Levels
J. Biol. Chem. 2002 277: 3065-3068. First Published on December 6, 2001; 10.1074/jbc.C100685200 [Abstract] [Full Text] [PDF]  

Meike Goenrich, Stefan Bartoschek, Christoph H. Hagemeier, Christian Griesinger, and Julia A. Vorholt
A Glutathione-dependent Formaldehyde-activating Enzyme (Gfa) from Paracoccus denitrificans Detected and Purified via Two-dimensional Proton Exchange NMR Spectroscopy
J. Biol. Chem. 2002 277: 3069-3072. First Published on December 10, 2001; 10.1074/jbc.C100579200 [Abstract] [Full Text] [PDF] Supplemental Data  


DNA: Replication Repair and Recombination:

Paola B. Arimondo, Alexandre Boutorine, Brigitte Baldeyrou, Christian Bailly, Masayasu Kuwahara, Sidney M. Hecht, Jian-Sheng Sun, Thérèse Garestier, and Claude Hélène
Design and Optimization of Camptothecin Conjugates of Triple Helix-forming Oligonucleotides for Sequence-specific DNA Cleavage by Topoisomerase I
J. Biol. Chem. 2002 277: 3132-3140. First Published on November 27, 2001; 10.1074/jbc.M110181200 [Abstract] [Full Text] [PDF]  

Mark C. Hall, Polina V. Shcherbakova, and Thomas A. Kunkel
Differential ATP Binding and Intrinsic ATP Hydrolysis by Amino-terminal Domains of the Yeast Mlh1 and Pms1 Proteins
J. Biol. Chem. 2002 277: 3673-3679. First Published on November 20, 2001; 10.1074/jbc.M106120200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Rosa M. Reguera, Rafael Balaña-Fouce, Yolanda Pérez-Pertejo, Francisco J. Fernández, Carlos García-Estrada, Juan C. Cubría, César Ordóñez, and David Ordóñez
Cloning Expression and Characterization of Methionine Adenosyltransferase in Leishmania infantum Promastigotes
J. Biol. Chem. 2002 277: 3158-3167. First Published on November 6, 2001; 10.1074/jbc.M105512200 [Abstract] [Full Text] [PDF]  

Teresa López-Rovira, Elisabet Chalaux, Joan Massagué, Jose Luis Rosa, and Francesc Ventura
Direct Binding of Smad1 and Smad4 to Two Distinct Motifs Mediates Bone Morphogenetic Protein-specific Transcriptional Activation of Id1 Gene
J. Biol. Chem. 2002 277: 3176-3185. First Published on November 7, 2001; 10.1074/jbc.M106826200 [Abstract] [Full Text] [PDF]  

José M. A. Moreira, Wolfram Hörz, and Steen Holmberg
Neither Reb1p nor Poly(dA·dT) Elements Are Responsible for the Highly Specific Chromatin Organization at the ILV1 Promoter
J. Biol. Chem. 2002 277: 3202-3209. First Published on November 8, 2001; 10.1074/jbc.M108962200 [Abstract] [Full Text] [PDF]  

William H. Hoffman, Siham Biade, Jack T. Zilfou, Jiandong Chen, and Maureen Murphy
Transcriptional Repression of the Anti-apoptotic survivin Gene by Wild Type p53
J. Biol. Chem. 2002 277: 3247-3257. First Published on November 19, 2001; 10.1074/jbc.M106643200 [Abstract] [Full Text] [PDF]  

Raffaela Pero, Francesca Lembo, Emiliano Antonio Palmieri, Carmen Vitiello, Monica Fedele, Alfredo Fusco, Carmelo Bruno Bruni, and Lorenzo Chiariotti
PATZ Attenuates the RNF4-mediated Enhancement of Androgen Receptor-dependent Transcription
J. Biol. Chem. 2002 277: 3280-3285. First Published on November 21, 2001; 10.1074/jbc.M109491200 [Abstract] [Full Text] [PDF]  

Amaris R. Guardiola and Tso-Pang Yao
Molecular Cloning and Characterization of a Novel Histone Deacetylase HDAC10
J. Biol. Chem. 2002 277: 3350-3356. First Published on November 28, 2001; 10.1074/jbc.M109861200 [Abstract] [Full Text] [PDF]  

Luis Felipe Jave-Suarez, Hermelita Winter, Lutz Langbein, Michael A. Rogers, and Jürgen Schweizer
HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression
J. Biol. Chem. 2002 277: 3718-3726. First Published on November 19, 2001; 10.1074/jbc.M101616200 [Abstract] [Full Text] [PDF]  


RNA: Structure Metabolism and Catalysis:

Luc Paillard, Vincent Legagneux, Dominique Maniey, and H. Beverley Osborne
c-Jun ARE Targets mRNA Deadenylation by an EDEN-BP (Embryo Deadenylation Element-binding Protein)-dependent Pathway
J. Biol. Chem. 2002 277: 3232-3235. First Published on November 13, 2001; 10.1074/jbc.M109362200 [Abstract] [Full Text] [PDF]  

Amanda Hicks, Robert G. Drager, David C. Higgs, and David B. Stern
An mRNA 3' Processing Site Targets Downstream Sequences for Rapid Degradation in Chlamydomonas Chloroplasts
J. Biol. Chem. 2002 277: 3325-3333. First Published on November 27, 2001; 10.1074/jbc.M108979200 [Abstract] [Full Text] [PDF]  

HyunDae D. Cho, Kozo Tomita, Tsutomu Suzuki, and Alan M. Weiner
U2 Small Nuclear RNA Is a Substrate for the CCA-adding Enzyme (tRNA Nucleotidyltransferase)
J. Biol. Chem. 2002 277: 3447-3455. First Published on November 7, 2001; 10.1074/jbc.M109559200 [Abstract] [Full Text] [PDF]  

Il-Ryong Choi and K. Andrew White
An RNA Activator of Subgenomic mRNA1 Transcription in Tomato Bushy Stunt Virus
J. Biol. Chem. 2002 277: 3760-3766. First Published on November 19, 2001; 10.1074/jbc.M109067200 [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

Dat Tran, Patti A. Tran, Yi-Quan Tang, Jun Yuan, Tim Cole, and Michael E. Selsted
Homodimeric theta -Defensins from Rhesus macaque Leukocytes. ISOLATION, SYNTHESIS, ANTIMICROBIAL ACTIVITIES, AND BACTERIAL BINDING PROPERTIES OF THE CYCLIC PEPTIDES
J. Biol. Chem. 2002 277: 3079-3084. First Published on October 23, 2001; 10.1074/jbc.M109117200 [Abstract] [Full Text] [PDF]  

Margo H. Furman, Hidde L. Ploegh, and Domenico Tortorella
Membrane-specific, Host-derived Factors Are Required for US2- and US11-mediated Degradation of Major Histocompatibility Complex Class I Molecules
J. Biol. Chem. 2002 277: 3258-3267. First Published on November 20, 2001; 10.1074/jbc.M109765200 [Abstract] [Full Text] [PDF]  

Gert C. Scheper, Barbara van Kollenburg, Jianzhong Hu, Yunjing Luo, Dixie J. Goss, and Christopher G. Proud
Phosphorylation of Eukaryotic Initiation Factor 4E Markedly Reduces Its Affinity for Capped mRNA
J. Biol. Chem. 2002 277: 3303-3309. First Published on November 26, 2001; 10.1074/jbc.M103607200 [Abstract] [Full Text] [PDF]  

Paul A. Voziyan, Thomas O. Metz, John W. Baynes, and Billy G. Hudson
A Post-Amadori Inhibitor Pyridoxamine Also Inhibits Chemical Modification of Proteins by Scavenging Carbonyl Intermediates of Carbohydrate and Lipid Degradation
J. Biol. Chem. 2002 277: 3397-3403. First Published on November 29, 2001; 10.1074/jbc.M109935200 [Abstract] [Full Text] [PDF]  

Yoshiomi Honda, Masahide Tojo, Kazuhito Matsuzaki, Tadashi Anan, Mitsuhiro Matsumoto, Masayuki Ando, Hideyuki Saya, and Mitsuyoshi Nakao
Cooperation of HECT-domain Ubiquitin Ligase hHYD and DNA Topoisomerase II-binding Protein for DNA Damage Response
J. Biol. Chem. 2002 277: 3599-3605. First Published on November 19, 2001; 10.1074/jbc.M104347200 [Abstract] [Full Text] [PDF]  

Arsalan S. Haqqani, John F. Kelly, and H. Chaim Birnboim
Selective Nitration of Histone Tyrosine Residues in Vivo in Mutatect Tumors
J. Biol. Chem. 2002 277: 3614-3621. First Published on November 26, 2001; 10.1074/jbc.M105730200 [Abstract] [Full Text] [PDF]  

Han-Jia Lin, Ching-Wei Luo, and Yee-Hsiung Chen
Localization of the Transglutaminase Cross-linking Site in SVS III, a Novel Glycoprotein Secreted from Mouse Seminal Vesicle
J. Biol. Chem. 2002 277: 3632-3639. First Published on November 26, 2001; 10.1074/jbc.M107578200 [Abstract] [Full Text] [PDF]  


Genomics Proteomics and Bioinformatics:

Christophe Roos, Meelis Kolmer, Pirkko Mattila, and Risto Renkonen
Composition of Drosophila melanogaster Proteome Involved in Fucosylated Glycan Metabolism
J. Biol. Chem. 2002 277: 3168-3175. First Published on November 6, 2001; 10.1074/jbc.M107927200 [Abstract] [Full Text] [PDF]  

Xiaowu Liang, Andy Teng, Dawn M. Braun, Jiin Felgner, Yan Wang, Scott I. Baker, Shizong Chen, Olivier Zelphati, and Philip L. Felgner
Transcriptionally Active Polymerase Chain Reaction (TAP). HIGH THROUGHPUT GENE EXPRESSION USING GENOME SEQUENCE DATA
J. Biol. Chem. 2002 277: 3593-3598. First Published on November 16, 2001; 10.1074/jbc.M110652200 [Abstract] [Full Text] [PDF]  

Seok Hong Min, Rosalia C. M. Simmen, Leena Alhonen, Maria Halmekytö, Carl W. Porter, Juhani Jänne, and Frank A. Simmen
Altered Levels of Growth-related and Novel Gene Transcripts in Reproductive and Other Tissues of Female Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase (SSAT)
J. Biol. Chem. 2002 277: 3647-3657. First Published on November 14, 2001; 10.1074/jbc.M100751200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Keith E. Shearwin, Ian B. Dodd, and J. Barry Egan
The Helix-Turn-Helix Motif of the Coliphage 186 Immunity Repressor Binds to Two Distinct Recognition Sequences
J. Biol. Chem. 2002 277: 3186-3194. First Published on November 7, 2001; 10.1074/jbc.M107740200 [Abstract] [Full Text] [PDF]  

Qiaofang Chen, Enbo Ma, Kevin L. Behar, Tian Xu, and Gabriel G. Haddad
Role of Trehalose Phosphate Synthase in Anoxia Tolerance and Development in Drosophila melanogaster
J. Biol. Chem. 2002 277: 3274-3279. First Published on November 21, 2001; 10.1074/jbc.M109479200 [Abstract] [Full Text] [PDF]  

Hideki Sakahira and Shigekazu Nagata
Co-translational Folding of Caspase-activated DNase with Hsp70, Hsp40, and Inhibitor of Caspase-activated DNase
J. Biol. Chem. 2002 277: 3364-3370. First Published on November 27, 2001; 10.1074/jbc.M110071200 [Abstract] [Full Text] [PDF]  

Arthur Oubrie, Henriëtte J. Rozeboom, Kor H. Kalk, Eric G. Huizinga, and Bauke W. Dijkstra
Crystal Structure of Quinohemoprotein Alcohol Dehydrogenase from Comamonas testosteroni. STRUCTURAL BASIS FOR SUBSTRATE OXIDATION AND ELECTRON TRANSFER
J. Biol. Chem. 2002 277: 3727-3732. First Published on November 19, 2001; 10.1074/jbc.M109403200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Carsten D. Richter, James W. A. Allen, Christopher W. Higham, Alrik Koppenhöfer, Richard S. Zajicek, Nicholas J. Watmough, and Stuart J. Ferguson
Cytochrome cd1, Reductive Activation and Kinetic Analysis of a Multifunctional Respiratory Enzyme
J. Biol. Chem. 2002 277: 3093-3100. First Published on November 14, 2001; 10.1074/jbc.M108944200 [Abstract] [Full Text] [PDF]  

Charles Burke and Rodney Croteau
Interaction with the Small Subunit of Geranyl Diphosphate Synthase Modifies the Chain Length Specificity of Geranylgeranyl Diphosphate Synthase to Produce Geranyl Diphosphate
J. Biol. Chem. 2002 277: 3141-3149. First Published on December 3, 2001; 10.1074/jbc.M105900200 [Abstract] [Full Text] [PDF]  

Gregory A. Kicska, Peter C. Tyler, Gary B. Evans, Richard H. Furneaux, Kami Kim, and Vern L. Schramm
Transition State Analogue Inhibitors of Purine Nucleoside Phosphorylase from Plasmodium falciparum
J. Biol. Chem. 2002 277: 3219-3225. First Published on November 13, 2001; 10.1074/jbc.M105905200 [Abstract] [Full Text] [PDF]  

Gregory A. Kicska, Peter C. Tyler, Gary B. Evans, Richard H. Furneaux, Vern L. Schramm, and Kami Kim
Purine-less Death in Plasmodium falciparum Induced by Immucillin-H, a Transition State Analogue of Purine Nucleoside Phosphorylase
J. Biol. Chem. 2002 277: 3226-3231. First Published on November 12, 2001; 10.1074/jbc.M105906200 [Abstract] [Full Text] [PDF]  

Kaisa Huhtinen, James O'Byrne, Per J. G. Lindquist, Juan A. Contreras, and Stefan E. H. Alexson
The Peroxisome Proliferator-induced Cytosolic Type I Acyl-CoA Thioesterase (CTE-I) Is a Serine-Histidine-Aspartic Acid alpha /beta Hydrolase
J. Biol. Chem. 2002 277: 3424-3432. First Published on November 2, 2001; 10.1074/jbc.M109040200 [Abstract] [Full Text] [PDF]  

Adam Frankel, Neelu Yadav, Jaeho Lee, Tina L. Branscombe, Steven Clarke, and Mark T. Bedford
The Novel Human Protein Arginine N-Methyltransferase PRMT6 Is a Nuclear Enzyme Displaying Unique Substrate Specificity
J. Biol. Chem. 2002 277: 3537-3543. First Published on November 27, 2001; 10.1074/jbc.M108786200 [Abstract] [Full Text] [PDF]  

Degang Zhong, Madhu S. Bajaj, Amy E. Schmidt, and S. Paul Bajaj
The N-terminal Epidermal Growth Factor-like Domain in Factor IX and Factor X Represents an Important Recognition Motif for Binding to Tissue Factor
J. Biol. Chem. 2002 277: 3622-3631. First Published on November 26, 2001; 10.1074/jbc.M111202200 [Abstract] [Full Text] [PDF]  

Andrea M. Olland, Kathryn W. Underwood, Robert M. Czerwinski, Mei-Chu Lo, Ann Aulabaugh, Joel Bard, Mark L. Stahl, William S. Somers, Francis X. Sullivan, and Rajiv Chopra
Identification, Characterization, and Crystal Structure of Bacillus subtilis Nicotinic Acid Mononucleotide Adenylyltransferase
J. Biol. Chem. 2002 277: 3698-3707. First Published on November 9, 2001; 10.1074/jbc.M109670200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Elisabeth Darrouzet, Maria Valkova-Valchanova, and Fevzi Daldal
The [2Fe-2S] Cluster Em as an Indicator of the Iron-Sulfur Subunit Position in the Ubihydroquinone Oxidation Site of the Cytochrome bc1 Complex
J. Biol. Chem. 2002 277: 3464-3470. First Published on November 13, 2001; 10.1074/jbc.M107973200 [Abstract] [Full Text] [PDF]  

Elisabeth Darrouzet and Fevzi Daldal
Movement of the Iron-Sulfur Subunit beyond the ef Loop of Cytochrome b Is Required for Multiple Turnovers of the bc1 Complex but Not for Single Turnover Qo Site Catalysis
J. Biol. Chem. 2002 277: 3471-3476. First Published on November 13, 2001; 10.1074/jbc.M107974200 [Abstract] [Full Text] [PDF]  

Christoph von Ballmoos, Yvonne Appoldt, Josef Brunner, Thierry Granier, Andrea Vasella, and Peter Dimroth
Membrane Topography of the Coupling Ion Binding Site in Na+-translocating F1F0 ATP Synthase
J. Biol. Chem. 2002 277: 3504-3510. First Published on November 21, 2001; 10.1074/jbc.M110301200 [Abstract] [Full Text] [PDF]  

Shiguang Liu, Rong Guo, Qisheng Tu, and L. Darryl Quarles
Overexpression of Phex in Osteoblasts Fails to Rescue the Hyp Mouse Phenotype
J. Biol. Chem. 2002 277: 3686-3697. First Published on November 16, 2001; 10.1074/jbc.M107707200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Seiichi Tagami, Jin-ichi Inokuchi, Kazuya Kabayama, Haruhiko Yoshimura, Futoshi Kitamura, Satoshi Uemura, Chie Ogawa, Atsushi Ishii, Masaki Saito, Yoshinori Ohtsuka, Shinji Sakaue, and Yasuyuki Igarashi
Ganglioside GM3 Participates in the Pathological Conditions of Insulin Resistance
J. Biol. Chem. 2002 277: 3085-3092. First Published on November 13, 2001; 10.1074/jbc.M103705200 [Abstract] [Full Text] [PDF]  

Rajan Somasundaram, Martin Ruehl, Benjamin Schaefer, Monika Schmid, Renate Ackermann, E. O. Riecken, Martin Zeitz, and Detlef Schuppan
Interstitial Collagens I, III, and VI Sequester and Modulate the Multifunctional Cytokine Oncostatin M
J. Biol. Chem. 2002 277: 3242-3246. First Published on November 15, 2001; 10.1074/jbc.M110011200 [Abstract] [Full Text] [PDF]  

Mark Nitz, Chang-Chun Ling, Albin Otter, Jim E. Cutler, and David R. Bundle
The Unique Solution Structure and Immunochemistry of the Candida albicans beta -1,2-Mannopyranan Cell Wall Antigens
J. Biol. Chem. 2002 277: 3440-3446. First Published on November 7, 2001; 10.1074/jbc.M109274200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ichiro Kuwabara, Yasuko Kuwabara, Ri-Yao Yang, Martin Schuler, Douglas R. Green, Bruce L. Zuraw, Daniel K. Hsu, and Fu-Tong Liu
Galectin-7 (PIG1) Exhibits Pro-apoptotic Function through JNK Activation and Mitochondrial Cytochrome c Release
J. Biol. Chem. 2002 277: 3487-3497. First Published on November 8, 2001; 10.1074/jbc.M109360200 [Abstract] [Full Text] [PDF] Supplemental Data  

Wang-Sik Lee, Jack Rohrer, Rosalind Kornfeld, and Stuart Kornfeld
Multiple Signals Regulate Trafficking of the Mannose 6-Phosphate-uncovering Enzyme
J. Biol. Chem. 2002 277: 3544-3551. First Published on November 26, 2001; 10.1074/jbc.M108531200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

James W. Furbee, Jr., Janet K. Sawyer, and John S. Parks
Lecithin:Cholesterol Acyltransferase Deficiency Increases Atherosclerosis in the Low Density Lipoprotein Receptor and Apolipoprotein E Knockout Mice
J. Biol. Chem. 2002 277: 3511-3519. First Published on November 21, 2001; 10.1074/jbc.M109883200 [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Ovidiu Pop, Ulrike Martin, Christian Abel, and Jörg P. Müller
The Twin-arginine Signal Peptide of PhoD and the TatAd/Cd Proteins of Bacillus subtilis Form an Autonomous Tat Translocation System
J. Biol. Chem. 2002 277: 3268-3273. First Published on November 21, 2001; 10.1074/jbc.M110829200 [Abstract] [Full Text] [PDF]  

Ellen J. Tisdale
Glyceraldehyde-3-phosphate Dehydrogenase Is Phosphorylated by Protein Kinase Ciota /lambda and Plays a Role in Microtubule Dynamics in the Early Secretory Pathway
J. Biol. Chem. 2002 277: 3334-3341. First Published on November 27, 2001; 10.1074/jbc.M109744200 [Abstract] [Full Text] [PDF]  

Yoichiro Arata, James D. Baleja, and Michael Forgac
Cysteine-directed Cross-linking to Subunit B Suggests That Subunit E Forms Part of the Peripheral Stalk of the Vacuolar H+-ATPase
J. Biol. Chem. 2002 277: 3357-3363. First Published on November 27, 2001; 10.1074/jbc.M109967200 [Abstract] [Full Text] [PDF]  

Phuong U. Le, Ginette Guay, Yoram Altschuler, and Ivan R. Nabi
Caveolin-1 Is a Negative Regulator of Caveolae-mediated Endocytosis to the Endoplasmic Reticulum
J. Biol. Chem. 2002 277: 3371-3379. First Published on November 27, 2001; 10.1074/jbc.M111240200 [Abstract] [Full Text] [PDF]  

Natàlia Dave, Víctor A. Lórenz-Fonfría, Joaquim Villaverde, Raymonde Lemonnier, Gérard Leblanc, and Esteve Padrós
Study of Amide-proton Exchange of Escherichia coli Melibiose Permease by Attenuated Total Reflection-Fourier Transform Infrared Spectroscopy. EVIDENCE OF STRUCTURE MODULATION BY SUBSTRATE BINDING
J. Biol. Chem. 2002 277: 3380-3387. First Published on November 29, 2001; 10.1074/jbc.M105466200 [Abstract] [Full Text] [PDF]  

Kota Saito, Jun Murai, Hiroaki Kajiho, Kenji Kontani, Hiroshi Kurosu, and Toshiaki Katada
A Novel Binding Protein Composed of Homophilic Tetramer Exhibits Unique Properties for the Small GTPase Rab5
J. Biol. Chem. 2002 277: 3412-3418. First Published on December 3, 2001; 10.1074/jbc.M106276200 [Abstract] [Full Text] [PDF]  

Mike Mueckler and Carol Makepeace
Analysis of Transmembrane Segment 10 of the Glut1 Glucose Transporter by Cysteine-scanning Mutagenesis and Substituted Cysteine Accessibility
J. Biol. Chem. 2002 277: 3498-3503. First Published on November 16, 2001; 10.1074/jbc.M109157200 [Abstract] [Full Text] [PDF]  

Jie Cheng, Bryan D. Moyer, Michal Milewski, Johannes Loffing, Masahiro Ikeda, John E. Mickle, Garry R. Cutting, Min Li, Bruce A. Stanton, and William B. Guggino
A Golgi-associated PDZ Domain Protein Modulates Cystic Fibrosis Transmembrane Regulator Plasma Membrane Expression
J. Biol. Chem. 2002 277: 3520-3529. First Published on November 13, 2001; 10.1074/jbc.M110177200 [Abstract] [Full Text] [PDF]  

Marieangela C. Wilson, David Meredith, and Andrew P. Halestrap
Fluorescence Resonance Energy Transfer Studies on the Interaction between the Lactate Transporter MCT1 and CD147 Provide Information on the Topology and Stoichiometry of the Complex in Situ
J. Biol. Chem. 2002 277: 3666-3672. First Published on November 21, 2001; 10.1074/jbc.M109658200 [Abstract] [Full Text] [PDF]  

Alex Böhm, Joachim Diez, Kay Diederichs, Wolfram Welte, and Winfried Boos
Structural Model of MalK, the ABC Subunit of the Maltose Transporter of Escherichia coli. IMPLICATIONS FOR mal GENE REGULATION, INDUCER EXCLUSION, AND SUBUNIT ASSEMBLY
J. Biol. Chem. 2002 277: 3708-3717. First Published on November 14, 2001; 10.1074/jbc.M107905200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Julian A. Tanner, Asif Abowath, and Andrew D. Miller
Isothermal Titration Calorimetry Reveals a Zinc Ion as an Atomic Switch in the Diadenosine Polyphosphates
J. Biol. Chem. 2002 277: 3073-3078. First Published on October 16, 2001; 10.1074/jbc.M106588200 [Abstract] [Full Text] [PDF]  

Renata Colavitti, Giovanni Pani, Barbara Bedogni, Rosanna Anzevino, Silvia Borrello, Johannes Waltenberger, and Tommaso Galeotti
Reactive Oxygen Species as Downstream Mediators of Angiogenic Signaling by Vascular Endothelial Growth Factor Receptor-2/KDR
J. Biol. Chem. 2002 277: 3101-3108. First Published on November 21, 2001; 10.1074/jbc.M107711200 [Abstract] [Full Text] [PDF]  

Clara Tan, Alice Mui, and Shoukat Dedhar
Integrin-linked Kinase Regulates Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Expression in an NF-kappa B-dependent Manner
J. Biol. Chem. 2002 277: 3109-3116. First Published on November 27, 2001; 10.1074/jbc.M108673200 [Abstract] [Full Text] [PDF]  

Masahiro Kido, Fumi Shima, Takaya Satoh, Tsuyoshi Asato, Ken-ichi Kariya, and Tohru Kataoka
Critical Function of the Ras-associating Domain as a Primary Ras-binding Site for Regulation of Saccharomyces cerevisiae Adenylyl Cyclase
J. Biol. Chem. 2002 277: 3117-3123. First Published on November 26, 2001; 10.1074/jbc.M109526200 [Abstract] [Full Text] [PDF]  

Yiguo Zhang, Wei-Ya Ma, Akira Kaji, Ann M. Bode, and Zigang Dong
Requirement of ATM in UVA-induced Signaling and Apoptosis
J. Biol. Chem. 2002 277: 3124-3131. First Published on November 26, 2001; 10.1074/jbc.M110245200 [Abstract] [Full Text] [PDF]  

Daniel Sliva, Maria T. Rizzo, and Denis English
Phosphatidylinositol 3-Kinase and NF-kappa B Regulate Motility of Invasive MDA-MB-231 Human Breast Cancer Cells by the Secretion of Urokinase-type Plasminogen Activator
J. Biol. Chem. 2002 277: 3150-3157. First Published on October 31, 2001; 10.1074/jbc.M109579200 [Abstract] [Full Text] [PDF]  

Permeen Yusoff, Dieu-Hung Lao, Siew Hwa Ong, Esther Sook Miin Wong, Jormay Lim, Ting Ling Lo, Hwei Fen Leong, Chee Wai Fong, and Graeme R. Guy
Sprouty2 Inhibits the Ras/MAP Kinase Pathway by Inhibiting the Activation of Raf
J. Biol. Chem. 2002 277: 3195-3201. First Published on November 6, 2001; 10.1074/jbc.M108368200 [Abstract] [Full Text] [PDF]  

Rosalind A. Le Feuvre, David Brough, Yoichiro Iwakura, Kiyoshi Takeda, and Nancy J. Rothwell
Priming of Macrophages with Lipopolysaccharide Potentiates P2X7-mediated Cell Death via a Caspase-1-dependent Mechanism, Independently of Cytokine Production
J. Biol. Chem. 2002 277: 3210-3218. First Published on November 12, 2001; 10.1074/jbc.M104388200 [Abstract] [Full Text] [PDF]  

Béatrice Duthey, Sara Caudron, Julie Perroy, Bernhard Bettler, Laurent Fagni, Jean-Philippe Pin, and Laurent Prézeau
A Single Subunit (GB2) Is Required for G-protein Activation by the Heterodimeric GABAB Receptor
J. Biol. Chem. 2002 277: 3236-3241. First Published on November 15, 2001; 10.1074/jbc.M108900200 [Abstract] [Full Text] [PDF]  

Nicole A. Bourbon, Lakshman Sandirasegarane, and Mark Kester
Ceramide-induced Inhibition of Akt Is Mediated through Protein Kinase Czeta . IMPLICATIONS FOR GROWTH ARREST
J. Biol. Chem. 2002 277: 3286-3292. First Published on November 26, 2001; 10.1074/jbc.M110541200 [Abstract] [Full Text] [PDF]  

Carlos O. Stocco, Lester F. Lau, and Geula Gibori
A Calcium/Calmodulin-dependent Activation of ERK1/2 Mediates JunD Phosphorylation and Induction of nur77 and 20alpha -hsd Genes by Prostaglandin F2alpha in Ovarian Cells
J. Biol. Chem. 2002 277: 3293-3302. First Published on November 21, 2001; 10.1074/jbc.M110936200 [Abstract] [Full Text] [PDF]  

Sergei D. Rybalkin, Irina G. Rybalkina, Robert Feil, Franz Hofmann, and Joseph A. Beavo
Regulation of cGMP-specific Phosphodiesterase (PDE5) Phosphorylation in Smooth Muscle Cells
J. Biol. Chem. 2002 277: 3310-3317. First Published on November 26, 2001; 10.1074/jbc.M106562200 [Abstract] [Full Text] [PDF]  

Mao Yang and Henry K. W. Fong
Synthesis of the All-trans-retinal Chromophore of Retinal G Protein-coupled Receptor Opsin in Cultured Pigment Epithelial Cells
J. Biol. Chem. 2002 277: 3318-3324. First Published on November 26, 2001; 10.1074/jbc.M108946200 [Abstract] [Full Text] [PDF]  

Yong Chool Boo, George Sorescu, Nolan Boyd, Ichiro Shiojima, Kenneth Walsh, Jie Du, and Hanjoong Jo
Shear Stress Stimulates Phosphorylation of Endothelial Nitric-oxide Synthase at Ser1179 by Akt-independent Mechanisms. ROLE OF PROTEIN KINASE A
J. Biol. Chem. 2002 277: 3388-3396. First Published on November 29, 2001; 10.1074/jbc.M108789200 [Abstract] [Full Text] [PDF]  

Jie Fan, Randall S. Frey, Arshad Rahman, and Asrar B. Malik
Role of Neutrophil NADPH Oxidase in the Mechanism of Tumor Necrosis Factor-alpha -induced NF-kappa B Activation and Intercellular Adhesion Molecule-1 Expression in Endothelial Cells
J. Biol. Chem. 2002 277: 3404-3411. First Published on November 29, 2001; 10.1074/jbc.M110054200 [Abstract] [Full Text] [PDF]  

Yakov Blumenstein, Nataly Kanevsky, Gideon Sahar, Rachel Barzilai, Tatiana Ivanina, and Nathan Dascal
A Novel Long N-terminal Isoform of Human L-type Ca2+ Channel Is Up-regulated by Protein Kinase C
J. Biol. Chem. 2002 277: 3419-3423. First Published on December 11, 2001; 10.1074/jbc.C100642200 [Abstract] [Full Text] [PDF]  

Yasujiro Morimitsu, Yoko Nakagawa, Kazuhiro Hayashi, Hiroyuki Fujii, Takeshi Kumagai, Yoshimasa Nakamura, Toshihiko Osawa, Fumihiko Horio, Ken Itoh, Katsuyuki Iida, Masayuki Yamamoto, and Koji Uchida
A Sulforaphane Analogue That Potently Activates the Nrf2-dependent Detoxification Pathway
J. Biol. Chem. 2002 277: 3456-3463. First Published on November 12, 2001; 10.1074/jbc.M110244200 [Abstract] [Full Text] [PDF]  

Mark G. H. Scott, Alexandre Benmerah, Olivier Muntaner, and Stefano Marullo
Recruitment of Activated G Protein-coupled Receptors to Pre-existing Clathrin-coated Pits in Living Cells
J. Biol. Chem. 2002 277: 3552-3559. First Published on October 15, 2001; 10.1074/jbc.M106586200 [Abstract] [Full Text] [PDF]  

Bharath Ananthanarayanan, Sudipto Das, Sue Goo Rhee, Diana Murray, and Wonhwa Cho
Membrane Targeting of C2 Domains of Phospholipase C-delta Isoforms
J. Biol. Chem. 2002 277: 3568-3575. First Published on November 12, 2001; 10.1074/jbc.M109705200 [Abstract] [Full Text] [PDF]  

Sabine Wolter, J. Frederic Mushinski, Ali M. Saboori, Klaus Resch, and Michael Kracht
Inducible Expression of a Constitutively Active Mutant of Mitogen-activated Protein Kinase Kinase 7 Specifically Activates c-JUN NH2-terminal Protein Kinase, Alters Expression of at Least Nine Genes, and Inhibits Cell Proliferation
J. Biol. Chem. 2002 277: 3576-3584. First Published on November 19, 2001; 10.1074/jbc.M105800200 [Abstract] [Full Text] [PDF]  

Hideaki Kaneto, Kiyoshi Suzuma, Arun Sharma, Susan Bonner-Weir, George L. King, and Gordon C. Weir
Involvement of Protein Kinase C beta 2 in c-myc Induction by High Glucose in Pancreatic beta -Cells
J. Biol. Chem. 2002 277: 3680-3685. First Published on November 19, 2001; 10.1074/jbc.M109647200 [Abstract] [Full Text] [PDF]  

Jarmo Laine, Gerald Künstle, Toshiyuki Obata, and Masayuki Noguchi
Differential Regulation of Akt Kinase Isoforms by the Members of the TCL1 Oncogene Family
J. Biol. Chem. 2002 277: 3743-3751. First Published on November 13, 2001; 10.1074/jbc.M107069200 [Abstract] [Full Text] [PDF]  

Michael Schaefer, Tim D. Plant, Nicole Stresow, Nadine Albrecht, and Günter Schultz
Functional Differences between TRPC4 Splice Variants
J. Biol. Chem. 2002 277: 3752-3759. First Published on November 16, 2001; 10.1074/jbc.M109850200 [Abstract] [Full Text] [PDF]  

Meir H. Scheinfeld, Roberta Roncarati, Pasquale Vito, Peter A. Lopez, Mona Abdallah, and Luciano D'Adamio
Jun NH2-terminal Kinase (JNK) Interacting Protein 1 (JIP1) Binds the Cytoplasmic Domain of the Alzheimer's beta -Amyloid Precursor Protein (APP)
J. Biol. Chem. 2002 277: 3767-3775. First Published on November 27, 2001; 10.1074/jbc.M108357200 [Abstract] [Full Text] [PDF]  

Xue Wei Meng, Michael P. Heldebrant, and Scott H. Kaufmann
Phorbol 12-myristate 13-Acetate Inhibits Death Receptor-mediated Apoptosis in Jurkat Cells by Disrupting Recruitment of Fas-associated Polypeptide with Death Domain
J. Biol. Chem. 2002 277: 3776-3783. First Published on November 29, 2001; 10.1074/jbc.M107218200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Fei Chen, Jacquelyn Bower, Stephen S. Leonard, Min Ding, Yongju Lu, Yon Rojanasakul, Hsiang-fu Kung, Val Vallyathan, Vince Castranova, and Xianglin Shi
Protective Roles of NF-kappa B for Chromium(VI)-induced Cytotoxicity Is Revealed by Expression of Ikappa B Kinase-beta Mutant
J. Biol. Chem. 2002 277: 3342-3349. First Published on November 28, 2001; 10.1074/jbc.M101089200 [Abstract] [Full Text] [PDF]  

Ellen Poon, Emily V. Howman, Sarah E. Newey, and Kay E. Davies
Association of Syncoilin and Desmin. LINKING INTERMEDIATE FILAMENT PROTEINS TO THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX
J. Biol. Chem. 2002 277: 3433-3439. First Published on November 1, 2001; 10.1074/jbc.M105273200 [Abstract] [Full Text] [PDF]  

Sarwar Hashmi, Collette Britton, Jing Liu, David B. Guiliano, Yelena Oksov, and Sara Lustigman
Cathepsin L Is Essential for Embryogenesis and Development of Caenorhabditis elegans
J. Biol. Chem. 2002 277: 3477-3486. First Published on November 13, 2001; 10.1074/jbc.M106117200 [Abstract] [Full Text] [PDF]  

Hsien-yu Wang, Jyotshnabala Kanungo, and Craig C. Malbon
Expression of Galpha 13 (Q226L) Induces P19 Stem Cells to Primitive Endoderm via MEKK1, 2, or 4
J. Biol. Chem. 2002 277: 3530-3536. First Published on November 7, 2001; 10.1074/jbc.M107031200 [Abstract] [Full Text] [PDF]  

S. Wesley Clark, Brian E. Fee, and John L. Cleveland
Misexpression of the Eyes Absent Family Triggers the Apoptotic Program
J. Biol. Chem. 2002 277: 3560-3567. First Published on November 7, 2001; 10.1074/jbc.M108410200 [Abstract] [Full Text] [PDF]  

Susan E. Crawford, Chao Qi, Parimal Misra, Veronica Stellmach, M. Sambasiva Rao, James D. Engel, Yijun Zhu, and Janardan K. Reddy
Defects of the Heart, Eye, and Megakaryocytes in Peroxisome Proliferator Activator Receptor-binding Protein (PBP) Null Embryos Implicate GATA Family of Transcription Factors
J. Biol. Chem. 2002 277: 3585-3592. First Published on November 27, 2001; 10.1074/jbc.M107995200 [Abstract] [Full Text] [PDF]  

Elvira Olaso, Juan-Pablo Labrador, LiHsien Wang, Kazuo Ikeda, Francis J. Eng, Rudiger Klein, David H. Lovett, Hsin Chieh Lin, and Scott L. Friedman
Discoidin Domain Receptor 2 Regulates Fibroblast Proliferation and Migration through the Extracellular Matrix in Association with Transcriptional Activation of Matrix Metalloproteinase-2
J. Biol. Chem. 2002 277: 3606-3613. First Published on November 26, 2001; 10.1074/jbc.M107571200 [Abstract] [Full Text] [PDF]  

Fumiaki Imamura, Shoji Maeda, Tomoko Doi, and Yoshinori Fujiyoshi
Ligand Binding of the Second PDZ Domain Regulates Clustering of PSD-95 with the Kv1.4 Potassium Channel
J. Biol. Chem. 2002 277: 3640-3646. First Published on November 26, 2001; 10.1074/jbc.M106940200 [Abstract] [Full Text] [PDF]  

Matthew J. Robinson, Philippe Tessier, Richard Poulsom, and Nancy Hogg
The S100 Family Heterodimer, MRP-8/14, Binds with High Affinity to Heparin and Heparan Sulfate Glycosaminoglycans on Endothelial Cells
J. Biol. Chem. 2002 277: 3658-3665. First Published on November 26, 2001; 10.1074/jbc.M102950200 [Abstract] [Full Text] [PDF]  

Minh-Hoa Dao-Thi, Daniel Charlier, Remy Loris, Dominique Maes, Joris Messens, Lode Wyns, and Jan Backmann
Intricate Interactions within the ccd Plasmid Addiction System
J. Biol. Chem. 2002 277: 3733-3742. First Published on December 7, 2001; 10.1074/jbc.M105505200 [Abstract] [Full Text] [PDF]  

Lance C. Bridges, Patricia H. Tani, Krista R. Hanson, Charles M. Roberts, Matthew B. Judkins, and Ron D. Bowditch
The Lymphocyte Metalloprotease MDC-L (ADAM 28) Is a Ligand for the Integrin alpha 4beta 1
J. Biol. Chem. 2002 277: 3784-3792. First Published on November 27, 2001; 10.1074/jbc.M109538200 [Abstract] [Full Text] [PDF]  

Tokiyoshi Ayabe, Heike Wulff, Dalila Darmoul, Michael D. Cahalan, K. George Chandy, and Andre J. Ouellette
Modulation of Mouse Paneth Cell alpha -Defensin Secretion by mIKCa1, a Ca2+-activated, Intermediate Conductance Potassium Channel
J. Biol. Chem. 2002 277: 3793-3800. First Published on November 27, 2001; 10.1074/jbc.M107507200 [Abstract] [Full Text] [PDF]  


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