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Table of Contents: Dec 13 2002; 277 (50)   [Index by Author]  [Cover Figure and Caption]
       Reflections
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Genomics Proteomics and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Reflections:

Bernard L. Horecker
The Pentose Phosphate Pathway
J. Biol. Chem. 2002 277: 47965-47971. First Published on October 25, 2002; 10.1074/jbc.X200007200 [Full Text] [PDF]  


Accelerated Publications:

Zhao Xu and Konstantin V. Kandror
Translocation of Small Preformed Vesicles Is Responsible for the Insulin Activation of Glucose Transport in Adipose Cells. EVIDENCE FROM THE IN VITRO RECONSTITUTION ASSAY
J. Biol. Chem. 2002 277: 47972-47975. First Published on October 21, 2002; 10.1074/jbc.C200486200 [Abstract] [Full Text] [PDF]  

Gerburg M. Wulf, Yih-Cherng Liou, Akihide Ryo, Sam W. Lee, and Kun Ping Lu
Role of Pin1 in the Regulation of p53 Stability and p21 Transactivation, and Cell Cycle Checkpoints in Response to DNA Damage
J. Biol. Chem. 2002 277: 47976-47979. First Published on October 17, 2002; 10.1074/jbc.C200538200 [Abstract] [Full Text] [PDF]  


DNA: Replication Repair and Recombination:

Jana Kasparkova, Jana Zehnulova, Nicholas Farrell, and Viktor Brabec
DNA Interstrand Cross-links of the Novel Antitumor Trinuclear Platinum Complex BBR3464. CONFORMATION, RECOGNITION BY HIGH MOBILITY GROUP DOMAIN PROTEINS, AND NUCLEOTIDE EXCISION REPAIR
J. Biol. Chem. 2002 277: 48076-48086. First Published on September 10, 2002; 10.1074/jbc.M208016200 [Abstract] [Full Text] [PDF]  

Ming H. Wu and Benjamin Y. M. Yung
UV Stimulation of Nucleophosmin/B23 Expression Is an Immediate-early Gene Response Induced by Damaged DNA
J. Biol. Chem. 2002 277: 48234-48240. First Published on October 8, 2002; 10.1074/jbc.M206550200 [Abstract] [Full Text] [PDF]  

Giovanni Maga, Giuseppe Villani, Kristijan Ramadan, Igor Shevelev, Nicolas Tanguy Le Gac, Luis Blanco, Giuseppina Blanca, Silvio Spadari, and Ulrich Hübscher
Human DNA Polymerase lambda Functionally and Physically Interacts with Proliferating Cell Nuclear Antigen in Normal and Translesion DNA Synthesis
J. Biol. Chem. 2002 277: 48434-48440. First Published on October 3, 2002; 10.1074/jbc.M206889200 [Abstract] [Full Text] [PDF]  

Takashi Okada, Eiichiro Sonoda, Yukiko M. Yamashita, Shogo Koyoshi, Satoshi Tateishi, Masaru Yamaizumi, Minoru Takata, Osamu Ogawa, and Shunichi Takeda
Involvement of Vertebrate Polkappa in Rad18-independent Postreplication Repair of UV Damage
J. Biol. Chem. 2002 277: 48690-48695. First Published on September 27, 2002; 10.1074/jbc.M207957200 [Abstract] [Full Text] [PDF] Supplemental Data  

Hiroyuki Kitao and Zhi-Min Yuan
Regulation of Ionizing Radiation-induced Rad52 Nuclear Foci Formation by c-Abl-mediated Phosphorylation
J. Biol. Chem. 2002 277: 48944-48948. First Published on October 11, 2002; 10.1074/jbc.M208151200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Mira A. Rao, Helen Cheng, Alandra N. Quayle, Hideo Nishitani, Colleen C. Nelson, and Paul S. Rennie
RanBPM, a Nuclear Protein That Interacts with and Regulates Transcriptional Activity of Androgen Receptor and Glucocorticoid Receptor
J. Biol. Chem. 2002 277: 48020-48027. First Published on October 1, 2002; 10.1074/jbc.M209741200 [Abstract] [Full Text] [PDF]  

Alain Bruhat, Julien Averous, Valérie Carraro, Can Zhong, Andreas M. Reimold, Michael S. Kilberg, and Pierre Fafournoux
Differences in the Molecular Mechanisms Involved in the Transcriptional Activation of the CHOP and Asparagine Synthetase Genes in Response to Amino Acid Deprivation or Activation of the Unfolded Protein Response
J. Biol. Chem. 2002 277: 48107-48114. First Published on September 25, 2002; 10.1074/jbc.M206149200 [Abstract] [Full Text] [PDF]  

Zoë A. Felton-Edkins and Robert J. White
Multiple Mechanisms Contribute to the Activation of RNA Polymerase III Transcription in Cells Transformed by Papovaviruses
J. Biol. Chem. 2002 277: 48182-48191. First Published on October 4, 2002; 10.1074/jbc.M201333200 [Abstract] [Full Text] [PDF]  

Keizou Ookawa, Toshihiro Kudo, Shu Aizawa, Hiroshi Saito, and Shigeki Tsuchida
Transcriptional Activation of the MUC2 Gene by p53
J. Biol. Chem. 2002 277: 48270-48275. First Published on October 8, 2002; 10.1074/jbc.M207986200 [Abstract] [Full Text] [PDF]  

Melissa L. Holmes, Natalie Bartle, Michael Eisbacher, and Beng H. Chong
Cloning and Analysis of the Thrombopoietin-induced Megakaryocyte-specific Glycoprotein VI Promoter and Its Regulation by GATA-1, Fli-1, and Sp1
J. Biol. Chem. 2002 277: 48333-48341. First Published on September 30, 2002; 10.1074/jbc.M206127200 [Abstract] [Full Text] [PDF]  

Chun-yi Zhang, Yu-Ling Wu, and Linda M. Boxer
Impaired Proliferation and Survival of Activated B Cells in Transgenic Mice That Express a Dominant-negative cAMP-response Element-binding Protein Transcription Factor in B Cells
J. Biol. Chem. 2002 277: 48359-48365. First Published on October 8, 2002; 10.1074/jbc.M209329200 [Abstract] [Full Text] [PDF]  

Zhigang Kang, Asta Pirskanen, Olli A. Jänne, and Jorma J. Palvimo
Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex
J. Biol. Chem. 2002 277: 48366-48371. First Published on October 9, 2002; 10.1074/jbc.M209074200 [Abstract] [Full Text] [PDF]  

Manjeet K. Rao, Chad M. Wayne, and Miles F. Wilkinson
Pem Homeobox Gene Regulatory Sequences That Direct Androgen-dependent Developmentally Regulated Gene Expression in Different Subregions of the Epididymis
J. Biol. Chem. 2002 277: 48771-48778. First Published on September 25, 2002; 10.1074/jbc.M209417200 [Abstract] [Full Text] [PDF]  

Hong Zhou, Vicky Kartsogiannis, Julian M. W. Quinn, Chi Ly, Christine Gange, Jan Elliott, Kong Wah Ng, and Matthew T. Gillespie
Osteoclast Inhibitory Lectin, a Family of New Osteoclast Inhibitors
J. Biol. Chem. 2002 277: 48808-48815. First Published on October 8, 2002; 10.1074/jbc.M209059200 [Abstract] [Full Text] [PDF]  

Daeyoup Lee, Chunghun Lim, Taegun Seo, Hyockman Kwon, Hyesun Min, and Joonho Choe
The Viral Oncogene Human Papillomavirus E7 Deregulates Transcriptional Silencing by Brm-related Gene 1 via Molecular Interactions
J. Biol. Chem. 2002 277: 48842-48848. First Published on October 7, 2002; 10.1074/jbc.M203583200 [Abstract] [Full Text] [PDF]  

Michael A. Rogers, Lutz Langbein, Hermelita Winter, Claudia Ehmann, Silke Praetzel, and Jürgen Schweizer
Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-associated Protein (KAP) Genes on Chromosome 21q22.1
J. Biol. Chem. 2002 277: 48993-49002. First Published on September 30, 2002; 10.1074/jbc.M206422200 [Abstract] [Full Text] [PDF]  


RNA: Structure Metabolism and Catalysis:

Kozo Tomita and Alan M. Weiner
Closely Related CC- and A-adding Enzymes Collaborate to Construct and Repair the 3'-Terminal CCA of tRNA in Synechocystis sp. and Deinococcus radiodurans
J. Biol. Chem. 2002 277: 48192-48198. First Published on October 4, 2002; 10.1074/jbc.M207527200 [Abstract] [Full Text] [PDF]  

Sander Granneman, Ger J. M. Pruijn, Wendy Horstman, Walther J. van Venrooij, Reinhard Lührmann, and Nicholas J. Watkins
The hU3-55K Protein Requires 15.5K Binding to the Box B/C Motif as Well as Flanking RNA Elements for Its Association with the U3 Small Nucleolar RNA in Vitro
J. Biol. Chem. 2002 277: 48490-48500. First Published on October 14, 2002; 10.1074/jbc.M206631200 [Abstract] [Full Text] [PDF]  

Mark T. Worthington, Jared W. Pelo, Muhammadreza A. Sachedina, Joan L. Applegate, Kristen O. Arseneau, and Theresa T. Pizarro
RNA Binding Properties of the AU-rich Element-binding Recombinant Nup475/TIS11/Tristetraprolin Protein
J. Biol. Chem. 2002 277: 48558-48564. First Published on September 24, 2002; 10.1074/jbc.M206505200 [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

Petra Schling and Thorsten Schäfer
Human Adipose Tissue Cells Keep Tight Control on the Angiotensin II Levels in Their Vicinity
J. Biol. Chem. 2002 277: 48066-48075. First Published on August 23, 2002; 10.1074/jbc.M204058200 [Abstract] [Full Text] [PDF]  

Chad R. Borges, Timothy Geddes, J. Throck Watson, and Donald M. Kuhn
Dopamine Biosynthesis Is Regulated by S-Glutathionylation. POTENTIAL MECHANISM OF TYROSINE HYDROXYLASE INHIBITION DURING OXIDATIVE STRESS
J. Biol. Chem. 2002 277: 48295-48302. First Published on October 9, 2002; 10.1074/jbc.M209042200 [Abstract] [Full Text] [PDF] Supplemental Data  

Eduardo A. Nillni, Weihua Xie, Lawrence Mulcahy, Vanesa C. Sanchez, and William C. Wetsel
Deficiencies in Pro-thyrotropin-releasing Hormone Processing and Abnormalities in Thermoregulation in Cpefat/fat Mice
J. Biol. Chem. 2002 277: 48587-48595. First Published on September 20, 2002; 10.1074/jbc.M206702200 [Abstract] [Full Text] [PDF]  

Heidi S.-T. Kai, Georgina S. Butler, Charlotte J. Morrison, Angela E. King, Gayle R. Pelman, and Christopher M. Overall
Utilization of a Novel Recombinant Myoglobin Fusion Protein Expression System to Characterize the Tissue Inhibitor of Metalloproteinase (TIMP)-4 and TIMP-2 C-terminal Domain and Tails by Mutagenesis. THE IMPORTANCE OF ACIDIC RESIDUES IN BINDING THE MMP-2 HEMOPEXIN C DOMAIN
J. Biol. Chem. 2002 277: 48696-48707. First Published on October 8, 2002; 10.1074/jbc.M209177200 [Abstract] [Full Text] [PDF]  

Parimal Misra, Edward D. Owuor, Wenge Li, Songtao Yu, Chao Qi, Kirstin Meyer, Yi-Jun Zhu, M. Sambasiva Rao, A.-N. Tony Kong, and Janardan K. Reddy
Phosphorylation of Transcriptional Coactivator Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein (PBP). STIMULATION OF TRANSCRIPTIONAL REGULATION BY MITOGEN-ACTIVATED PROTEIN KINASE
J. Biol. Chem. 2002 277: 48745-48754. First Published on September 27, 2002; 10.1074/jbc.M208829200 [Abstract] [Full Text] [PDF]  

Ryoji Nagai, Cristina Miki Hayashi, Ling Xia, Motohiro Takeya, and Seikoh Horiuchi
Identification in Human Atherosclerotic Lesions of GA-pyridine, a Novel Structure Derived from Glycolaldehyde-modified Proteins
J. Biol. Chem. 2002 277: 48905-48912. First Published on October 10, 2002; 10.1074/jbc.M205688200 [Abstract] [Full Text] [PDF]  

He-Jin Lee and Seung-Jae Lee
Characterization of Cytoplasmic alpha -Synuclein Aggregates. FIBRIL FORMATION IS TIGHTLY LINKED TO THE INCLUSION-FORMING PROCESS IN CELLS
J. Biol. Chem. 2002 277: 48976-48983. First Published on September 25, 2002; 10.1074/jbc.M208192200 [Abstract] [Full Text] [PDF]  

Nirmal Gosavi, He-Jin Lee, Jun Sung Lee, Smita Patel, and Seung-Jae Lee
Golgi Fragmentation Occurs in the Cells with Prefibrillar alpha -Synuclein Aggregates and Precedes the Formation of Fibrillar Inclusion
J. Biol. Chem. 2002 277: 48984-48992. First Published on September 25, 2002; 10.1074/jbc.M208194200 [Abstract] [Full Text] [PDF]  

Masato Hasegawa, Hideo Fujiwara, Takashi Nonaka, Koichi Wakabayashi, Hitoshi Takahashi, Virginia M.-Y. Lee, John Q. Trojanowski, David Mann, and Takeshi Iwatsubo
Phosphorylated alpha -Synuclein Is Ubiquitinated in alpha -Synucleinopathy Lesions
J. Biol. Chem. 2002 277: 49071-49076. First Published on October 10, 2002; 10.1074/jbc.M208046200 [Abstract] [Full Text] [PDF]  


Genomics Proteomics and Bioinformatics:

Dmitry A. Rodionov, Alexey G. Vitreschak, Andrey A. Mironov, and Mikhail S. Gelfand
Comparative Genomics of Thiamin Biosynthesis in Procaryotes. NEW GENES AND REGULATORY MECHANISMS
J. Biol. Chem. 2002 277: 48949-48959. First Published on October 9, 2002; 10.1074/jbc.M208965200 [Abstract] [Full Text] [PDF] Supplemental Data  

Alison L. Woo, Lucy A. Gildea, Leslie M. Tack, Marian L. Miller, Zachary Spicer, David E. Millhorn, Fred D. Finkelman, Daniel J. Hassett, and Gary E. Shull
In Vivo Evidence for Interferon-gamma -mediated Homeostatic Mechanisms in Small Intestine of the NHE3 Na+/H+ Exchanger Knockout Model of Congenital Diarrhea
J. Biol. Chem. 2002 277: 49036-49046. First Published on October 4, 2002; 10.1074/jbc.M205288200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Luigi Mandrich, Emilia Caputo, Brian M. Martin, Mosè Rossi, and Giuseppe Manco
The Aes Protein and the Monomeric alpha -Galactosidase from Escherichia coli Form a Non-covalent Complex. IMPLICATIONS FOR THE REGULATION OF CARBOHYDRATE METABOLISM
J. Biol. Chem. 2002 277: 48241-48247. First Published on October 8, 2002; 10.1074/jbc.M207398200 [Abstract] [Full Text] [PDF]  

Jana Oliveriusová, Vladimír Kery, Kenneth N. Maclean, and Jan P. Kraus
Deletion Mutagenesis of Human Cystathionine beta -Synthase. IMPACT ON ACTIVITY, OLIGOMERIC STATUS, AND S-ADENOSYLMETHIONINE REGULATION
J. Biol. Chem. 2002 277: 48386-48394. First Published on October 11, 2002; 10.1074/jbc.M207087200 [Abstract] [Full Text] [PDF]  

Angela Valbuzzi and Charles Yanofsky
Zinc Is Required for Assembly and Function of the Anti-trp RNA-binding Attenuation Protein, AT
J. Biol. Chem. 2002 277: 48574-48578. First Published on October 16, 2002; 10.1074/jbc.M208980200 [Abstract] [Full Text] [PDF]  

Songlin Li, Jim Finley, Zhi-Jie Liu, Shi-Hong Qiu, Hongli Chen, Chi-Hao Luan, Mike Carson, Jun Tsao, David Johnson, Guangda Lin, Jun Zhao, Willie Thomas, Lisa A. Nagy, Bingdong Sha, Lawrence J. DeLucas, Bi-Cheng Wang, and Ming Luo
Crystal Structure of the Cytoskeleton-associated Protein Glycine-rich (CAP-Gly) Domain
J. Biol. Chem. 2002 277: 48596-48601. First Published on September 7, 2002; 10.1074/jbc.M208512200 [Abstract] [Full Text] [PDF]  

Valentin P. Yakubenko, Valeryi K. Lishko, Stephen C.-T. Lam, and Tatiana P. Ugarova
A Molecular Basis for Integrin alpha Mbeta 2 Ligand Binding Promiscuity
J. Biol. Chem. 2002 277: 48635-48642. First Published on October 10, 2002; 10.1074/jbc.M208877200 [Abstract] [Full Text] [PDF]  

Aniello Russo, Antonella Antignani, Concetta Giancola, and Giuseppe D'Alessio
Engineering the Refolding Pathway and the Quaternary Structure of Seminal Ribonuclease by Newly Introduced Disulfide Bridges
J. Biol. Chem. 2002 277: 48643-48649. First Published on October 10, 2002; 10.1074/jbc.M207141200 [Abstract] [Full Text] [PDF]  

Peter B. Crowley, Antonio Díaz-Quintana, Fernando P. Molina-Heredia, Pedro Nieto, Martin Sutter, Wolfgang Haehnel, Miguel A. De la Rosa, and Marcellus Ubbink
The Interactions of Cyanobacterial Cytochrome c6 and Cytochrome f, Characterized by NMR
J. Biol. Chem. 2002 277: 48685-48689. First Published on September 27, 2002; 10.1074/jbc.M203983200 [Abstract] [Full Text] [PDF] Supplemental Data  

Jie Liu and Min Lu
An Alanine-Zipper Structure Determined by Long Range Intermolecular Interactions
J. Biol. Chem. 2002 277: 48708-48713. First Published on October 3, 2002; 10.1074/jbc.M208773200 [Abstract] [Full Text] [PDF]  

Ravichandran N. Venkataramani, Timothy K. MacLachlan, Xiaomei Chai, Wafik S. El-Deiry, and Ronen Marmorstein
Structure-based Design of p18INK4c Proteins with Increased Thermodynamic Stability and Cell Cycle Inhibitory Activity
J. Biol. Chem. 2002 277: 48827-48833. First Published on October 4, 2002; 10.1074/jbc.M208061200 [Abstract] [Full Text] [PDF]  

Julie L. Dutton, Paramjit S. Bansal, Ron C. Hogg, David J. Adams, Paul F. Alewood, and David J. Craik
A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity
J. Biol. Chem. 2002 277: 48849-48857. First Published on October 9, 2002; 10.1074/jbc.M208842200 [Abstract] [Full Text] [PDF]  

Zhongzhen Nie, Katherine T. Stanley, Stacey Stauffer, Kerry M. Jacques, Dianne S. Hirsch, Jiro Takei, and Paul A. Randazzo
AGAP1, an Endosome-associated, Phosphoinositide-dependent ADP-ribosylation Factor GTPase-activating Protein That Affects Actin Cytoskeleton
J. Biol. Chem. 2002 277: 48965-48975. First Published on October 17, 2002; 10.1074/jbc.M202969200 [Abstract] [Full Text] [PDF]  

David L. Vanik and Witold K. Surewicz
Disease-associated F198S Mutation Increases the Propensity of the Recombinant Prion Protein for Conformational Conversion to Scrapie-like Form
J. Biol. Chem. 2002 277: 49065-49070. First Published on October 7, 2002; 10.1074/jbc.M207511200 [Abstract] [Full Text] [PDF]  

Mary Jo Mulligan-Kehoe, Hynda K. Kleinman, Mary Drinane, Robert J. Wagner, Courtney Wieland, and Richard J. Powell
A Truncated Plasminogen Activator Inhibitor-1 Protein Blocks the Availability of Heparin-binding Vascular Endothelial Growth Factor A Isoforms
J. Biol. Chem. 2002 277: 49077-49089. First Published on October 14, 2002; 10.1074/jbc.M208757200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Beom Seok Kim, T. Ashton Cropp, Brian J. Beck, David H. Sherman, and Kevin A. Reynolds
Biochemical Evidence for an Editing Role of Thioesterase II in the Biosynthesis of the Polyketide Pikromycin
J. Biol. Chem. 2002 277: 48028-48034. First Published on October 3, 2002; 10.1074/jbc.M207770200 [Abstract] [Full Text] [PDF]  

Vaka S. Reddy and Anireddy S. N. Reddy
The Calmodulin-binding Domain from a Plant Kinesin Functions as a Modular Domain in Conferring Ca2+-Calmodulin Regulation to Animal Plus- and Minus-end Kinesins
J. Biol. Chem. 2002 277: 48058-48065. First Published on October 13, 2002; 10.1074/jbc.M205459200 [Abstract] [Full Text] [PDF]  

Erick Strauss and Tadhg P. Begley
The Antibiotic Activity of N-Pentylpantothenamide Results from Its Conversion to Ethyldethia-Coenzyme A, a Coenzyme A Antimetabolite
J. Biol. Chem. 2002 277: 48205-48209. First Published on October 7, 2002; 10.1074/jbc.M204560200 [Abstract] [Full Text] [PDF]  

Uwe Schlomann, Dirk Wildeboer, Ailsa Webster, Olga Antropova, Dagmar Zeuschner, C. Graham Knight, Andrew J. P. Docherty, Marc Lambert, Lisa Skelton, Harald Jockusch, and Jörg W. Bartsch
The Metalloprotease Disintegrin ADAM8. PROCESSING BY AUTOCATALYSIS IS REQUIRED FOR PROTEOLYTIC ACTIVITY AND CELL ADHESION
J. Biol. Chem. 2002 277: 48210-48219. First Published on October 7, 2002; 10.1074/jbc.M203355200 [Abstract] [Full Text] [PDF]  

Katsuro Yaoi and Yasushi Mitsuishi
Purification, Characterization, Cloning, and Expression of a Novel Xyloglucan-specific Glycosidase, Oligoxyloglucan Reducing End-specific Cellobiohydrolase
J. Biol. Chem. 2002 277: 48276-48281. First Published on October 8, 2002; 10.1074/jbc.M208443200 [Abstract] [Full Text] [PDF]  

Jinwoo Ahn and Carol Prives
Checkpoint Kinase 2 (Chk2) Monomers or Dimers Phosphorylate Cdc25C after DNA Damage Regardless of Threonine 68 Phosphorylation
J. Biol. Chem. 2002 277: 48418-48426. First Published on October 16, 2002; 10.1074/jbc.M208321200 [Abstract] [Full Text] [PDF]  

Vittorio Pandini, Gianluca Caprini, Nadine Thomsen, Alessandro Aliverti, Frank Seeber, and Giuliana Zanetti
Ferredoxin-NADP+ Reductase and Ferredoxin of the Protozoan Parasite Toxoplasma gondii Interact Productively in Vitro and in Vivo
J. Biol. Chem. 2002 277: 48463-48471. First Published on October 4, 2002; 10.1074/jbc.M209388200 [Abstract] [Full Text] [PDF]  

Tiebang Kang, Hyun I. Park, Yewseok Suh, Yun-Ge Zhao, Harald Tschesche, and Qing-Xiang Amy Sang
Autolytic Processing at Glu586-Ser587 within the Cysteine-rich Domain of Human Adamalysin 19/Disintegrin-Metalloproteinase 19 Is Necessary for Its Proteolytic Activity
J. Biol. Chem. 2002 277: 48514-48522. First Published on October 18, 2002; 10.1074/jbc.M208961200 [Abstract] [Full Text] [PDF]  

Sofiane Bezzine, James G. Bollinger, Alan G. Singer, Sarah L. Veatch, Sarah L. Keller, and Michael H. Gelb
On the Binding Preference of Human Groups IIA and X Phospholipases A2 for Membranes with Anionic Phospholipids
J. Biol. Chem. 2002 277: 48523-48534. First Published on September 19, 2002; 10.1074/jbc.M203137200 [Abstract] [Full Text] [PDF]  

Alan G. Singer, Farideh Ghomashchi, Catherine Le Calvez, James Bollinger, Sofiane Bezzine, Morgane Rouault, Martin Sadilek, Eric Nguyen, Michel Lazdunski, Gérard Lambeau, and Michael H. Gelb
Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2
J. Biol. Chem. 2002 277: 48535-48549. First Published on September 30, 2002; 10.1074/jbc.M205855200 [Abstract] [Full Text] [PDF]  

Stefan Schauer, Shalini Chaturvedi, Lennart Randau, Jürgen Moser, Makoto Kitabatake, Stefan Lorenz, Elizabeth Verkamp, Wolf-Dieter Schubert, Toru Nakayashiki, Masatoshi Murai, Kristen Wall, Hans-Ulrich Thomann, Dirk W. Heinz, Hachiro Inokuchi, Dieter Söll, and Dieter Jahn
Escherichia coli Glutamyl-tRNA Reductase. TRAPPING THE THIOESTER INTERMEDIATE
J. Biol. Chem. 2002 277: 48657-48663. First Published on October 4, 2002; 10.1074/jbc.M206924200 [Abstract] [Full Text] [PDF]  

C. Lee Elmore and Todd D. Porter
Modification of the Nucleotide Cofactor-binding Site of Cytochrome P-450 Reductase to Enhance Turnover with NADH in Vivo
J. Biol. Chem. 2002 277: 48960-48964. First Published on October 14, 2002; 10.1074/jbc.M210173200 [Abstract] [Full Text] [PDF]  

Kenji Soejima, Masato Yuguchi, Jun Mizuguchi, Kazuhiko Tomokiyo, Toshihiro Nakashima, Tomohiro Nakagaki, and Sadaaki Iwanaga
The 99 and 170 Loop-modified Factor VIIa Mutants Show Enhanced Catalytic Activity without Tissue Factor
J. Biol. Chem. 2002 277: 49027-49035. First Published on October 2, 2002; 10.1074/jbc.M203091200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Axel Magalon, Chantal Frixon, Jeanine Pommier, Gérard Giordano, and Francis Blasco
In Vivo Interactions between Gene Products Involved in the Final Stages of Molybdenum Cofactor Biosynthesis in Escherichia coli
J. Biol. Chem. 2002 277: 48199-48204. First Published on October 7, 2002; 10.1074/jbc.M205806200 [Abstract] [Full Text] [PDF]  

Raúl Covián, Juan Pablo Pardo, and Rafael Moreno-Sánchez
Tight Binding of Inhibitors to Bovine bc1 Complex Is Independent of the Rieske Protein Redox State. CONSEQUENCES FOR SEMIQUINONE STABILIZATION IN THE QUINOL OXIDATION SITE
J. Biol. Chem. 2002 277: 48449-48455. First Published on October 2, 2002; 10.1074/jbc.M208060200 [Abstract] [Full Text] [PDF]  

Susanne Brunner, Valerie Everard-Gigot, and Rosemary A. Stuart
Su e of the Yeast F1Fo-ATP Synthase Forms Homodimers
J. Biol. Chem. 2002 277: 48484-48489. First Published on October 10, 2002; 10.1074/jbc.M209382200 [Abstract] [Full Text] [PDF]  

Nianning Qi, Ludmila Kazdova, Vaclav Zidek, Vladimir Landa, Vladimir Kren, Harrihar A. Pershadsingh, Elizabeth St. Lezin, Nada A. Abumrad, Michal Pravenec, and Theodore W. Kurtz
Pharmacogenetic Evidence That Cd36 Is a Key Determinant of the Metabolic Effects of Pioglitazone
J. Biol. Chem. 2002 277: 48501-48507. First Published on October 15, 2002; 10.1074/jbc.M206655200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Samuel K. Shinjo, Ivarne L. S. Tersariol, Vitor Oliveira, Clóvis R. Nakaie, Maria E. M. Oshiro, Alice T. Ferreira, Isabel A. Santos, Carl P. Dietrich, and Helena B. Nader
Heparin and Heparan Sulfate Disaccharides Bind to the Exchanger Inhibitor Peptide Region of Na+/Ca2+ Exchanger and Reduce the Cytosolic Calcium of Smooth Muscle Cell Lines. REQUIREMENT OF C4-C5 UNSATURATION AND 1 right-arrow 4 GLYCOSIDIC LINKAGE FOR ACTIVITY
J. Biol. Chem. 2002 277: 48227-48233. First Published on October 8, 2002; 10.1074/jbc.M205867200 [Abstract] [Full Text] [PDF]  

Guohui Ren, Mona Doshi, Bradley K. Hack, Jessy J. Alexander, and Richard J. Quigg
Isolation and Characterization of a Novel Rat Factor H-related Protein That Is Up-regulated in Glomeruli under Complement Attack
J. Biol. Chem. 2002 277: 48351-48358. First Published on October 8, 2002; 10.1074/jbc.M205135200 [Abstract] [Full Text] [PDF]  

Lynn M. Thomson, Douglas J. Lamont, Angela Mehlert, J. David Barry, and Michael A. J. Ferguson
Partial Structure of Glutamic Acid and Alanine-rich Protein, a Major Surface Glycoprotein of the Insect Stages of Trypanosoma congolense
J. Biol. Chem. 2002 277: 48899-48904. First Published on October 3, 2002; 10.1074/jbc.M208942200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Hélène Duez, Yu-Sheng Chao, Melba Hernandez, Gérard Torpier, Philippe Poulain, Steven Mundt, Ziad Mallat, Elisabeth Teissier, Charlotte A. Burton, Alain Tedgui, Jean-Charles Fruchart, Catherine Fiévet, Sam D. Wright, and Bart Staels
Reduction of Atherosclerosis by the Peroxisome Proliferator-activated Receptor alpha Agonist Fenofibrate in Mice
J. Biol. Chem. 2002 277: 48051-48057. First Published on October 10, 2002; 10.1074/jbc.M206966200 [Abstract] [Full Text] [PDF]  

Alejandra R. Diaz, María C. Mansilla, Alejandro J. Vila, and Diego de Mendoza
Membrane Topology of the Acyl-Lipid Desaturase from Bacillus subtilis
J. Biol. Chem. 2002 277: 48099-48106. First Published on September 24, 2002; 10.1074/jbc.M208960200 [Abstract] [Full Text] [PDF] Supplemental Data  

Desiree van der Kleij, Eicke Latz, Jos F. H. M. Brouwers, Yvonne C. M. Kruize, Marion Schmitz, Evelyn A. Kurt-Jones, Terje Espevik, Esther C. de Jong, Martien L. Kapsenberg, Douglas T. Golenbock, Aloysius G. M. Tielens, and Maria Yazdanbakhsh
A Novel Host-Parasite Lipid Cross-talk. SCHISTOSOMAL LYSO-PHOSPHATIDYLSERINE ACTIVATES TOLL-LIKE RECEPTOR 2 AND AFFECTS IMMUNE POLARIZATION
J. Biol. Chem. 2002 277: 48122-48129. First Published on September 30, 2002; 10.1074/jbc.M206941200 [Abstract] [Full Text] [PDF]  

William M. Pandak, Shunlin Ren, Dalila Marques, Elizabeth Hall, Kaye Redford, Darrell Mallonee, Patricia Bohdan, Douglas Heuman, Gregorio Gil, and Phillip Hylemon
Transport of Cholesterol into Mitochondria Is Rate-limiting for Bile Acid Synthesis via the Alternative Pathway in Primary Rat Hepatocytes
J. Biol. Chem. 2002 277: 48158-48164. First Published on October 3, 2002; 10.1074/jbc.M205244200 [Abstract] [Full Text] [PDF]  

Joanna K. Davies, Robert M. Hagan, and David C. Wilton
Effect of Charge Reversal Mutations on the Ligand- and Membrane-binding Properties of Liver Fatty Acid-binding Protein
J. Biol. Chem. 2002 277: 48395-48402. First Published on October 11, 2002; 10.1074/jbc.M208141200 [Abstract] [Full Text] [PDF]  

Hiroaki Fukumoto, Amy Deng, Michael C. Irizarry, Michael L. Fitzgerald, and G. William Rebeck
Induction of the Cholesterol Transporter ABCA1 in Central Nervous System Cells by Liver X Receptor Agonists Increases Secreted Abeta Levels
J. Biol. Chem. 2002 277: 48508-48513. First Published on October 15, 2002; 10.1074/jbc.M209085200 [Abstract] [Full Text] [PDF]  

Junken Aoki, Akitsu Taira, Yasukazu Takanezawa, Yasuhiro Kishi, Kotaro Hama, Tatsuya Kishimoto, Koji Mizuno, Keijiro Saku, Ryo Taguchi, and Hiroyuki Arai
Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways
J. Biol. Chem. 2002 277: 48737-48744. First Published on September 26, 2002; 10.1074/jbc.M206812200 [Abstract] [Full Text] [PDF]  

Rien van Haperen, Monique de Waard, Elza van Deel, Barend Mees, Michael Kutryk, Thijs van Aken, Jaap Hamming, Frank Grosveld, Dirk J. Duncker, and Rini de Crom
Reduction of Blood Pressure, Plasma Cholesterol, and Atherosclerosis by Elevated Endothelial Nitric Oxide
J. Biol. Chem. 2002 277: 48803-48807. First Published on October 2, 2002; 10.1074/jbc.M209477200 [Abstract] [Full Text] [PDF]  

Rien van Haperen, Arie van Tol, Teus van Gent, Leo Scheek, Pim Visser, Arthur van der Kamp, Frank Grosveld, and Rini de Crom
Increased Risk of Atherosclerosis by Elevated Plasma Levels of Phospholipid Transfer Protein
J. Biol. Chem. 2002 277: 48938-48943. First Published on October 7, 2002; 10.1074/jbc.M209128200 [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Csilla Özvegy, András Váradi, and Balázs Sarkadi
Characterization of Drug Transport, ATP Hydrolysis, and Nucleotide Trapping by the Human ABCG2 Multidrug Transporter. MODULATION OF SUBSTRATE SPECIFICITY BY A POINT MUTATION
J. Biol. Chem. 2002 277: 47980-47990. First Published on October 8, 2002; 10.1074/jbc.M207857200 [Abstract] [Full Text] [PDF]  

Francisco S. Cayabyab, Florence W. L. Tsui, and Lyanne C. Schlichter
Modulation of the ERG K+ Current by the Tyrosine Phosphatase, SHP-1
J. Biol. Chem. 2002 277: 48130-48138. First Published on October 1, 2002; 10.1074/jbc.M208448200 [Abstract] [Full Text] [PDF]  

Yuan Guo, Gareth J. Waldron, and Ruth Murrell-Lagnado
A Role for the Middle C Terminus of G-protein-activated Inward Rectifier Potassium Channels in Regulating Gating
J. Biol. Chem. 2002 277: 48289-48294. First Published on October 9, 2002; 10.1074/jbc.M207987200 [Abstract] [Full Text] [PDF]  

Symeon Siniossoglou and Hugh R. B. Pelham
Vps51p Links the VFT Complex to the SNARE Tlg1p
J. Biol. Chem. 2002 277: 48318-48324. First Published on October 10, 2002; 10.1074/jbc.M209428200 [Abstract] [Full Text] [PDF]  

Xiao-Fang Li, Alexander S. Kraev, and Jonathan Lytton
Molecular Cloning of a Fourth Member of the Potassium-dependent Sodium-Calcium Exchanger Gene Family, NCKX4
J. Biol. Chem. 2002 277: 48410-48417. First Published on October 11, 2002; 10.1074/jbc.M210011200 [Abstract] [Full Text] [PDF]  

Hiroyuki Mori, Yuhsuke Shimizu, and Koreaki Ito
Superactive SecY Variants That Fulfill the Essential Translocation Function with a Reduced Cellular Quantity
J. Biol. Chem. 2002 277: 48550-48557. First Published on September 25, 2002; 10.1074/jbc.M204436200 [Abstract] [Full Text] [PDF]  

Aimée Paulussen, Adam Raes, Gert Matthijs, Dirk J. Snyders, Nadine Cohen, and Jeroen Aerssens
A Novel Mutation (T65P) in the PAS Domain of the Human Potassium Channel HERG Results in the Long QT Syndrome by Trafficking Deficiency
J. Biol. Chem. 2002 277: 48610-48616. First Published on September 26, 2002; 10.1074/jbc.M206569200 [Abstract] [Full Text] [PDF]  

Claudia O. Rodrigues, Felix A. Ruiz, Peter Rohloff, David A. Scott, and Silvia N. J. Moreno
Characterization of Isolated Acidocalcisomes from Toxoplasma gondii Tachyzoites Reveals a Novel Pool of Hydrolyzable Polyphosphate
J. Biol. Chem. 2002 277: 48650-48656. First Published on October 11, 2002; 10.1074/jbc.M208990200 [Abstract] [Full Text] [PDF]  

Isabel C. Morrow, Shane Rea, Sally Martin, Ian A. Prior, Rainer Prohaska, John F. Hancock, David E. James, and Robert G. Parton
Flotillin-1/Reggie-2 Traffics to Surface Raft Domains via a Novel Golgi-independent Pathway. IDENTIFICATION OF A NOVEL MEMBRANE TARGETING DOMAIN AND A ROLE FOR PALMITOYLATION
J. Biol. Chem. 2002 277: 48834-48841. First Published on October 4, 2002; 10.1074/jbc.M209082200 [Abstract] [Full Text] [PDF]  

Ellen M. van Dam, Toine ten Broeke, Karen Jansen, Patricia Spijkers, and Willem Stoorvogel
Endocytosed Transferrin Receptors Recycle via Distinct Dynamin and Phosphatidylinositol 3-Kinase-dependent Pathways
J. Biol. Chem. 2002 277: 48876-48883. First Published on October 7, 2002; 10.1074/jbc.M206271200 [Abstract] [Full Text] [PDF]  

Xinjiang Cai, Kathy Zhang, and Jonathan Lytton
A Novel Topology and Redox Regulation of the Rat Brain K+-dependent Na+/Ca2+ Exchanger, NCKX2
J. Biol. Chem. 2002 277: 48923-48930. First Published on October 10, 2002; 10.1074/jbc.M208818200 [Abstract] [Full Text] [PDF]  

Jaehoon Jung, Taesook Yoon, Eung Chil Choi, and Kyunglim Lee
Interaction of Cofilin with Triose-phosphate Isomerase Contributes Glycolytic Fuel for Na,K-ATPase via Rho-mediated Signaling Pathway
J. Biol. Chem. 2002 277: 48931-48937. First Published on September 30, 2002; 10.1074/jbc.M208806200 [Abstract] [Full Text] [PDF]  

Jennifer M. Meyers and Rytis Prekeris
Formation of Mutually Exclusive Rab11 Complexes with Members of the Family of Rab11-interacting Proteins Regulates Rab11 Endocytic Targeting and Function
J. Biol. Chem. 2002 277: 49003-49010. First Published on October 9, 2002; 10.1074/jbc.M205728200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Yenshou Lin, Andrei Khokhlatchev, Daniel Figeys, and Joseph Avruch
Death-associated Protein 4 Binds MST1 and Augments MST1-induced Apoptosis
J. Biol. Chem. 2002 277: 47991-48001. First Published on October 15, 2002; 10.1074/jbc.M202630200 [Abstract] [Full Text] [PDF]  

Ji Suk Chang, Kenneth Henry, Bianka L. Wolf, Maribel Geli, and Sandra K. Lemmon
Protein Phosphatase-1 Binding to Scd5p Is Important for Regulation of Actin Organization and Endocytosis in Yeast
J. Biol. Chem. 2002 277: 48002-48008. First Published on September 27, 2002; 10.1074/jbc.M208471200 [Abstract] [Full Text] [PDF]  

Nathalie Strutz, Carmen Villmann, Hans-Georg Breitinger, Markus Werner, Robert J. Wenthold, Pablo Kizelsztein, Vivian I. Teichberg, and Michael Hollmann
Kainate-binding Proteins Are Rendered Functional Ion Channels upon Transplantation of Two Short Pore-flanking Domains from a Kainate Receptor
J. Biol. Chem. 2002 277: 48035-48042. First Published on October 5, 2002; 10.1074/jbc.M209647200 [Abstract] [Full Text] [PDF]  

Amir H. Salehi, Steven Xanthoudakis, and Philip A. Barker
NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway
J. Biol. Chem. 2002 277: 48043-48050. First Published on October 9, 2002; 10.1074/jbc.M205324200 [Abstract] [Full Text] [PDF]  

Gray W. Pearson and Melanie H. Cobb
Cell Condition-dependent Regulation of ERK5 by cAMP
J. Biol. Chem. 2002 277: 48094-48098. First Published on September 23, 2002; 10.1074/jbc.M208535200 [Abstract] [Full Text] [PDF]  

Zhanguo Gao, Daniel Hwang, Fredly Bataille, Michael Lefevre, David York, Michael J. Quon, and Jianping Ye
Serine Phosphorylation of Insulin Receptor Substrate 1 by Inhibitor kappa B Kinase Complex
J. Biol. Chem. 2002 277: 48115-48121. First Published on September 25, 2002; 10.1074/jbc.M209459200 [Abstract] [Full Text] [PDF] Supplemental Data  

Steffen Gross, Christophe Blanchetot, Jan Schepens, Sabrina Albet, Reiner Lammers, Jeroen den Hertog, and Wiljan Hendriks
Multimerization of the Protein-tyrosine Phosphatase (PTP)-like Insulin-dependent Diabetes Mellitus Autoantigens IA-2 and IA-2beta with Receptor PTPs (RPTPs). INHIBITION OF RPTPalpha ENZYMATIC ACTIVITY
J. Biol. Chem. 2002 277: 48139-48145. First Published on October 2, 2002; 10.1074/jbc.M208228200 [Abstract] [Full Text] [PDF]  

Edith Gomez, Catrin Pritchard, and Terence P. Herbert
cAMP-dependent Protein Kinase and Ca2+ Influx through L-type Voltage-gated Calcium Channels Mediate Raf-independent Activation of Extracellular Regulated Kinase in Response to Glucagon-like Peptide-1 in Pancreatic beta -Cells
J. Biol. Chem. 2002 277: 48146-48151. First Published on October 2, 2002; 10.1074/jbc.M209165200 [Abstract] [Full Text] [PDF]  

Jing-Jy Cheng, Yuen-Jen Chao, and Danny Ling Wang
Cyclic Strain Activates Redox-sensitive Proline-rich Tyrosine Kinase 2 (PYK2) in Endothelial Cells
J. Biol. Chem. 2002 277: 48152-48157. First Published on October 3, 2002; 10.1074/jbc.M110937200 [Abstract] [Full Text] [PDF]  

Bin-Xian Zhang, Xiuye Ma, Chih-Ko Yeh, Meyer D. Lifschitz, Michael X. Zhu, and Michael S. Katz
Epidermal Growth Factor-induced Depletion of the Intracellular Ca2+ Store Fails to Activate Capacitative Ca2+ Entry in a Human Salivary Cell Line
J. Biol. Chem. 2002 277: 48165-48171. First Published on October 3, 2002; 10.1074/jbc.M208077200 [Abstract] [Full Text] [PDF]  

Jason I. E. Bruce, David I. Yule, and Trevor J. Shuttleworth
Ca2+-dependent Protein Kinase-A Modulation of the Plasma Membrane Ca2+-ATPase in Parotid Acinar Cells
J. Biol. Chem. 2002 277: 48172-48181. First Published on October 3, 2002; 10.1074/jbc.M208393200 [Abstract] [Full Text] [PDF]  

Anna Usacheva, Raudel Sandoval, Paul Domanski, Sergei V. Kotenko, Keats Nelms, Mark A. Goldsmith, and Oscar R. Colamonici
Contribution of the Box 1 and Box 2 Motifs of Cytokine Receptors to Jak1 Association and Activation
J. Biol. Chem. 2002 277: 48220-48226. First Published on October 8, 2002; 10.1074/jbc.M205757200 [Abstract] [Full Text] [PDF]  

Daniel L. Galvan and Gregory A. Mignery
Carboxyl-terminal Sequences Critical for Inositol 1,4,5-Trisphosphate Receptor Subunit Assembly
J. Biol. Chem. 2002 277: 48248-48260. First Published on October 10, 2002; 10.1074/jbc.M209990200 [Abstract] [Full Text] [PDF]  

Neil J. Freedman, Luke K. Kim, John P. Murray, Sabrina T. Exum, Leigh Brian, Jiao-Hui Wu, and Karsten Peppel
Phosphorylation of the Platelet-derived Growth Factor Receptor-beta and Epidermal Growth Factor Receptor by G Protein-coupled Receptor Kinase-2. MECHANISMS FOR SELECTIVITY OF DESENSITIZATION
J. Biol. Chem. 2002 277: 48261-48269. First Published on October 14, 2002; 10.1074/jbc.M204431200 [Abstract] [Full Text] [PDF]  

Ilham Bettahi, Cheryl L. Marker, Maria I. Roman, and Kevin Wickman
Contribution of the Kir3.1 Subunit to the Muscarinic-gated Atrial Potassium Channel IKACh
J. Biol. Chem. 2002 277: 48282-48288. First Published on October 8, 2002; 10.1074/jbc.M209599200 [Abstract] [Full Text] [PDF]  

Monu Goel, William G. Sinkins, and William P. Schilling
Selective Association of TRPC Channel Subunits in Rat Brain Synaptosomes
J. Biol. Chem. 2002 277: 48303-48310. First Published on October 10, 2002; 10.1074/jbc.M207882200 [Abstract] [Full Text] [PDF] Supplemental Data  

Yuren Wang, Guyu Ho, Jerry J. Zhang, Bart Nieuwenhuijsen, Wade Edris, Pranab K. Chanda, and Kathleen H. Young
Regulator of G Protein Signaling Z1 (RGSZ1) Interacts with Galpha i Subunits and Regulates Galpha i-mediated Cell Signaling
J. Biol. Chem. 2002 277: 48325-48332. First Published on October 11, 2002; 10.1074/jbc.M206116200 [Abstract] [Full Text] [PDF]  

Kiyotsugu Yoshida, Yoshio Miki, and Donald Kufe
Activation of SAPK/JNK Signaling by Protein Kinase Cdelta in Response to DNA Damage
J. Biol. Chem. 2002 277: 48372-48378. First Published on October 10, 2002; 10.1074/jbc.M205485200 [Abstract] [Full Text] [PDF]  

Qiwei Han, Jay Leng, Dafang Bian, Chitladda Mahanivong, Kevin A. Carpenter, Zhixing K. Pan, Jiahuai Han, and Shuang Huang
Rac1-MKK3-p38-MAPKAPK2 Pathway Promotes Urokinase Plasminogen Activator mRNA Stability in Invasive Breast Cancer Cells
J. Biol. Chem. 2002 277: 48379-48385. First Published on October 10, 2002; 10.1074/jbc.M209542200 [Abstract] [Full Text] [PDF]  

Elisabeth L. Pagé, Geneviève A. Robitaille, Jacques Pouysségur, and Darren E. Richard
Induction of Hypoxia-inducible Factor-1alpha by Transcriptional and Translational Mechanisms
J. Biol. Chem. 2002 277: 48403-48409. First Published on October 11, 2002; 10.1074/jbc.M209114200 [Abstract] [Full Text] [PDF]  

Gele Liu, Liliane Robillard, Behzad Banihashemi, and Paul R. Albert
Growth Hormone-induced Diacylglycerol and Ceramide Formation via Galpha i3 and Gbeta gamma in GH4 Pituitary Cells. POTENTIATION BY DOPAMINE-D2 RECEPTOR ACTIVATION
J. Biol. Chem. 2002 277: 48427-48433. First Published on October 9, 2002; 10.1074/jbc.M202130200 [Abstract] [Full Text] [PDF]  

A. Soren Leonard, K.-Ulrich Bayer, Michelle A. Merrill, Indra A. Lim, Madeline A. Shea, Howard Schulman, and Johannes W. Hell
Regulation of Calcium/Calmodulin-dependent Protein Kinase II Docking to N-Methyl-D-aspartate Receptors by Calcium/Calmodulin and alpha -Actinin
J. Biol. Chem. 2002 277: 48441-48448. First Published on October 13, 2002; 10.1074/jbc.M205164200 [Abstract] [Full Text] [PDF]  

Bing-e Xu, Xiaoshan Min, Steve Stippec, Byung-Hoon Lee, Elizabeth J. Goldsmith, and Melanie H. Cobb
Regulation of WNK1 by an Autoinhibitory Domain and Autophosphorylation
J. Biol. Chem. 2002 277: 48456-48462. First Published on October 8, 2002; 10.1074/jbc.M207917200 [Abstract] [Full Text] [PDF]  

Xin Zhang, Won-Suk Kim, Nathan Hatcher, Kurt Potgieter, Leonid L. Moroz, Rhanor Gillette, and Jonathan V. Sweedler
Interfering with Nitric Oxide Measurements. 4,5-DIAMINOFLUORESCEIN REACTS WITH DEHYDROASCORBIC ACID AND ASCORBIC ACID
J. Biol. Chem. 2002 277: 48472-48478. First Published on October 4, 2002; 10.1074/jbc.M209130200 [Abstract] [Full Text] [PDF]  

Linda Björnström and Maria Sjöberg
Mutations in the Estrogen Receptor DNA-binding Domain Discriminate between the Classical Mechanism of Action and Cross-talk with Stat5b and Activating Protein 1 (AP-1)
J. Biol. Chem. 2002 277: 48479-48483. First Published on October 30, 2002; 10.1074/jbc.C200570200 [Abstract] [Full Text] [PDF]  

Adam B. Keeton, Maggie O. Amsler, Derwei Y. Venable, and Joseph L. Messina
Insulin Signal Transduction Pathways and Insulin-induced Gene Expression
J. Biol. Chem. 2002 277: 48565-48573. First Published on October 2, 2002; 10.1074/jbc.M207837200 [Abstract] [Full Text] [PDF]  

Julie Pannequin, Kevin J. Barnham, Frédéric Hollande, Arthur Shulkes, Raymond S. Norton, and Graham S. Baldwin
Ferric Ions Are Essential for the Biological Activity of the Hormone Glycine-extended Gastrin
J. Biol. Chem. 2002 277: 48602-48609. First Published on September 20, 2002; 10.1074/jbc.M208440200 [Abstract] [Full Text] [PDF]  

Eva van Rooij, Pieter A. Doevendans, Chiel C. de Theije, Fawzi A. Babiker, Jeffery D. Molkentin, and Leon J. De Windt
Requirement of Nuclear Factor of Activated T-cells in Calcineurin-mediated Cardiomyocyte Hypertrophy
J. Biol. Chem. 2002 277: 48617-48626. First Published on September 10, 2002; 10.1074/jbc.M206532200 [Abstract] [Full Text] [PDF]  

Colleen M. Sheridan, E. Kevin Heist, Chan R. Beals, Gerald R. Crabtree, and Phyllis Gardner
Protein Kinase A Negatively Modulates the Nuclear Accumulation of NF-ATc1 by Priming for Subsequent Phosphorylation by Glycogen Synthase Kinase-3
J. Biol. Chem. 2002 277: 48664-48676. First Published on September 25, 2002; 10.1074/jbc.M207029200 [Abstract] [Full Text] [PDF]  

Jun You, Christopher R. Jacobs, Thomas H. Steinberg, and Henry J. Donahue
P2Y Purinoceptors Are Responsible for Oscillatory Fluid Flow-induced Intracellular Calcium Mobilization in Osteoblastic Cells
J. Biol. Chem. 2002 277: 48724-48729. First Published on October 9, 2002; 10.1074/jbc.M209245200 [Abstract] [Full Text] [PDF]  

Gyles E. Cozier, Jez Carlton, Alex H. McGregor, Paul A. Gleeson, Rohan D. Teasdale, Harry Mellor, and Peter J. Cullen
The Phox Homology (PX) Domain-dependent, 3-Phosphoinositide-mediated Association of Sorting Nexin-1 with an Early Sorting Endosomal Compartment Is Required for Its Ability to Regulate Epidermal Growth Factor Receptor Degradation
J. Biol. Chem. 2002 277: 48730-48736. First Published on August 26, 2002; 10.1074/jbc.M206986200 [Abstract] [Full Text] [PDF]  

Yan-Shi Guo, Ji-Zhong Cheng, Gui-Fang Jin, J. Silvio Gutkind, Mark R. Hellmich, and Courtney M. Townsend, Jr.
Gastrin Stimulates Cyclooxygenase-2 Expression in Intestinal Epithelial Cells through Multiple Signaling Pathways. EVIDENCE FOR INVOLVEMENT OF ERK5 KINASE AND TRANSACTIVATION OF THE EPIDERMAL GROWTH FACTOR RECEPTOR
J. Biol. Chem. 2002 277: 48755-48763. First Published on September 17, 2002; 10.1074/jbc.M209016200 [Abstract] [Full Text] [PDF]  

Sheng T. Hou, Xiaoqi Xie, Anne Baggley, David S. Park, Gao Chen, and Teena Walker
Activation of the Rb/E2F1 Pathway by the Nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated Neuronal Apoptosis
J. Biol. Chem. 2002 277: 48764-48770. First Published on September 25, 2002; 10.1074/jbc.M206336200 [Abstract] [Full Text] [PDF]  

Simon A. Walker, Sabine Kupzig, Peter J. Lockyer, Sara Bilu, Dorit Zharhary, and Peter J. Cullen
Analyzing the Role of the Putative Inositol 1,3,4,5-Tetrakisphosphate Receptor GAP1IP4BP in Intracellular Ca2+ Homeostasis
J. Biol. Chem. 2002 277: 48779-48785. First Published on September 27, 2002; 10.1074/jbc.M204839200 [Abstract] [Full Text] [PDF]  

Hiromichi Fujino, Dinesh Srinivasan, and John W. Regan
Cellular Conditioning and Activation of beta -Catenin Signaling by the FPB Prostanoid Receptor
J. Biol. Chem. 2002 277: 48786-48795. First Published on October 3, 2002; 10.1074/jbc.M209393200 [Abstract] [Full Text] [PDF]  

Mark L. Dell'Acqua, Kimberly L. Dodge, Steven J. Tavalin, and John D. Scott
Mapping the Protein Phosphatase-2B Anchoring Site on AKAP79. BINDING AND INHIBITION OF PHOSPHATASE ACTIVITY ARE MEDIATED BY RESIDUES 315-360
J. Biol. Chem. 2002 277: 48796-48802. First Published on September 26, 2002; 10.1074/jbc.M207833200 [Abstract] [Full Text] [PDF]  

Xiao-Jian Yao, Julie Lemay, Nicole Rougeau, Martin Clément, Steve Kurtz, Pierre Belhumeur, and Éric A. Cohen
Genetic Selection of Peptide Inhibitors of Human Immunodeficiency Virus Type 1 Vpr
J. Biol. Chem. 2002 277: 48816-48826. First Published on October 11, 2002; 10.1074/jbc.M207982200 [Abstract] [Full Text] [PDF]  

Qiang Fu, Robert L. Jilka, Stavros C. Manolagas, and Charles A. O'Brien
Parathyroid Hormone Stimulates Receptor Activator of NFkappa B Ligand and Inhibits Osteoprotegerin Expression via Protein Kinase A Activation of cAMP-response Element-binding Protein
J. Biol. Chem. 2002 277: 48868-48875. First Published on October 2, 2002; 10.1074/jbc.M208494200 [Abstract] [Full Text] [PDF]  

Raphaël Rousset, Keith A. Wharton, Jr., Gregor Zimmermann, and Matthew P. Scott
Zinc-dependent Interaction between Dishevelled and the Drosophila Wnt Antagonist Naked Cuticle
J. Biol. Chem. 2002 277: 49019-49026. First Published on September 26, 2002; 10.1074/jbc.M203246200 [Abstract] [Full Text] [PDF]  

Jennifer N. Gass, Nicole M. Gifford, and Joseph W. Brewer
Activation of an Unfolded Protein Response during Differentiation of Antibody-secreting B Cells
J. Biol. Chem. 2002 277: 49047-49054. First Published on October 8, 2002; 10.1074/jbc.M205011200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

James B. Petro, Rachel M. Gerstein, John Lowe, Robert S. Carter, Nicholas Shinners, and Wasif N. Khan
Transitional Type 1 and 2 B Lymphocyte Subsets Are Differentially Responsive to Antigen Receptor Signaling
J. Biol. Chem. 2002 277: 48009-48019. First Published on September 28, 2002; 10.1074/jbc.M200305200 [Abstract] [Full Text] [PDF]  

Sarah E. Whitehead, Kevin W. Jones, Xing Zhang, Xiaodong Cheng, Rebecca M. Terns, and Michael P. Terns
Determinants of the Interaction of the Spinal Muscular Atrophy Disease Protein SMN with the Dimethylarginine-modified Box H/ACA Small Nucleolar Ribonucleoprotein GAR1
J. Biol. Chem. 2002 277: 48087-48093. First Published on September 19, 2002; 10.1074/jbc.M204551200 [Abstract] [Full Text] [PDF]  

Hua Cai, Zongming Li, Sergey Dikalov, Steven M. Holland, Jinah Hwang, Hanjoong Jo, Samuel C. Dudley, Jr., and David G. Harrison
NAD(P)H Oxidase-derived Hydrogen Peroxide Mediates Endothelial Nitric Oxide Production in Response to Angiotensin II
J. Biol. Chem. 2002 277: 48311-48317. First Published on October 10, 2002; 10.1074/jbc.M208884200 [Abstract] [Full Text] [PDF]  

Julie Vadnais, Geneviève Nault, Zeinab Daher, Mohammad Amraei, Yolaine Dodier, Ivan Robert Nabi, and Josette Noël
Autocrine Activation of the Hepatocyte Growth Factor Receptor/Met Tyrosine Kinase Induces Tumor Cell Motility by Regulating Pseudopodial Protrusion
J. Biol. Chem. 2002 277: 48342-48350. First Published on October 7, 2002; 10.1074/jbc.M209481200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ketut Suardita, Katsumi Fujimoto, Ryo Oda, Atsushi Shimazu, Kazuko Miyazaki, Takeshi Kawamoto, and Yukio Kato
Effects of Overexpression of Membrane-bound Transferrin-like Protein (MTf) on Chondrogenic Differentiation in Vitro
J. Biol. Chem. 2002 277: 48579-48586. First Published on October 8, 2002; 10.1074/jbc.M209243200 [Abstract] [Full Text] [PDF]  

Ana A. Kitazono and Stephen J. Kron
An Essential Function of Yeast Cyclin-dependent Kinase Cdc28 Maintains Chromosome Stability
J. Biol. Chem. 2002 277: 48627-48634. First Published on September 30, 2002; 10.1074/jbc.M207247200 [Abstract] [Full Text] [PDF]  

Zifei Pei, Galit Reske, Qihong Huang, Bruce D. Hammock, Yipeng Qi, and Nor Chejanovsky
Characterization of the Apoptosis Suppressor Protein P49 from the Spodoptera littoralis Nucleopolyhedrovirus
J. Biol. Chem. 2002 277: 48677-48684. First Published on September 24, 2002; 10.1074/jbc.M208810200 [Abstract] [Full Text] [PDF]  

Hirotaka Sakai, Takeshi Urano, Kayoko Ookata, Mi-Hyun Kim, Yugo Hirai, Motoki Saito, Yoshihisa Nojima, and Fuyuki Ishikawa
MBD3 and HDAC1, Two Components of the NuRD Complex, Are Localized at Aurora-A-positive Centrosomes in M Phase
J. Biol. Chem. 2002 277: 48714-48723. First Published on September 26, 2002; 10.1074/jbc.M208461200 [Abstract] [Full Text] [PDF]  

Ziqiang Spoerl, Maria Stumpf, Angelika A. Noegel, and Andreas Hasse
Oligomerization, F-actin Interaction, and Membrane Association of the Ubiquitous Mammalian Coronin 3 Are Mediated by Its Carboxyl Terminus
J. Biol. Chem. 2002 277: 48858-48867. First Published on October 10, 2002; 10.1074/jbc.M205136200 [Abstract] [Full Text] [PDF]  

Eri Taniguchi, Fumiko Toyoshima-Morimoto, and Eisuke Nishida
Nuclear Translocation of Plk1 Mediated by Its Bipartite Nuclear Localization Signal
J. Biol. Chem. 2002 277: 48884-48888. First Published on October 2, 2002; 10.1074/jbc.M206307200 [Abstract] [Full Text] [PDF]  

Tomoji Maeda, Deborah L. Chapman, and Alexandre F. R. Stewart
Mammalian Vestigial-like 2, a Cofactor of TEF-1 and MEF2 Transcription Factors That Promotes Skeletal Muscle Differentiation
J. Biol. Chem. 2002 277: 48889-48898. First Published on October 9, 2002; 10.1074/jbc.M206858200 [Abstract] [Full Text] [PDF]  

Xuemin Xu, Yong-chang Shi, Wei Gao, Guozhang Mao, Guojun Zhao, Sudesh Agrawal, Guy M. Chisolm, Dexin Sui, and Mei-Zhen Cui
The Novel Presenilin-1-associated Protein Is a Proapoptotic Mitochondrial Protein
J. Biol. Chem. 2002 277: 48913-48922. First Published on October 10, 2002; 10.1074/jbc.M209613200 [Abstract] [Full Text] [PDF]  

Yasuhiro Takeuchi, Sumiyo Watanabe, Genichiro Ishii, Shu Takeda, Konosuke Nakayama, Seiji Fukumoto, Yasuyuki Kaneta, Daisuke Inoue, Toshio Matsumoto, Kenichi Harigaya, and Toshiro Fujita
Interleukin-11 as a Stimulatory Factor for Bone Formation Prevents Bone Loss with Advancing Age in Mice
J. Biol. Chem. 2002 277: 49011-49018. First Published on October 15, 2002; 10.1074/jbc.M207804200 [Abstract] [Full Text] [PDF]  

Sherry S. H. Wu, Der Fen Suen, Han Chang Chang, and Anthony H. C. Huang
Maize Tapetum Xylanase Is Synthesized as a Precursor, Processed and Activated by a Serine Protease, and Deposited on the Pollen
J. Biol. Chem. 2002 277: 49055-49064. First Published on October 3, 2002; 10.1074/jbc.M208804200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:

James P. Bridges, Harold W. Davis, Mamatha Damodarasamy, Yoshio Kuroki, Gabriel Howles, David Y. Hui, and Francis X. McCormack
Pulmonary surfactant proteins A and D are potent endogenous inhibitors of lipid peroxidation and oxidative cellular injury.
J. Biol. Chem. 2002 277: 49090. [Full Text] [PDF]  


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