JBC -- Table of Contents (Dec 20 2002, 277, (51))

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Reflections:

Thressa Campbell Stadtman: A Gold Mine of Fascinating Enzymes: Those Remarkable, Strictly Anaerobic Bacteria, Methanococcus vannielii and Clostridium sticklandii
J. Biol. Chem. 2002 277: 49091-49100. First Published on October 25, 2002; 10.1074/jbc.X200005200 [Full Text] [PDF]

Accelerated Publications:

Marianna Tcherpakov, Francisca C. Bronfman, Silvestro G. Conticello, Anna Vaskovsky, Zehava Levy, Michio Niinobe, Kazuaki Yoshikawa, Ernest Arenas, and Mike Fainzilber: The p75 Neurotrophin Receptor Interacts with Multiple MAGE Proteins
J. Biol. Chem. 2002 277: 49101-49104. First Published on October 31, 2002; 10.1074/jbc.C200533200 [Abstract] [Full Text] [PDF]

DNA: Replication Repair and Recombination:

Adam P. Silverman, Weiming Bu, Seth M. Cohen, and Stephen J. Lippard: 2.4-Å Crystal Structure of the Asymmetric Platinum Complex {Pt(ammine)(cyclohexylamine)}²⁺ Bound to a Dodecamer DNA Duplex
J. Biol. Chem. 2002 277: 49743-49749. First Published on October 10, 2002; 10.1074/jbc.M206979200 [Abstract] [Full Text] [PDF]

José A. Carrodeguas, Kevin G. Pinz, and Daniel F. Bogenhagen: DNA Binding Properties of Human pol $gamma$ B
J. Biol. Chem. 2002 277: 50008-50014. First Published on October 11, 2002; 10.1074/jbc.M207030200 [Abstract] [Full Text] [PDF]

Laurence Servant, Christophe Cazaux, Anne Bieth, Shigenori Iwai, Fumio Hanaoka, and Jean-Sébastien Hoffmann: A Role for DNA Polymerase $beta$ in Mutagenic UV Lesion Bypass
J. Biol. Chem. 2002 277: 50046-50053. First Published on October 17, 2002; 10.1074/jbc.M207101200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Valerie Christiaens, Charlotte L. Bevan, Leen Callewaert, Anna Haelens, Guy Verrijdt, Wilfried Rombauts, and Frank Claessens: Characterization of the Two Coactivator-interacting Surfaces of the Androgen Receptor and Their Relative Role in Transcriptional Control^*
J. Biol. Chem. 2002 277: 49230-49237. First Published on October 4, 2002; 10.1074/jbc.M209322200 [Abstract] [Full Text] [PDF]

Yuanzheng He, Daniele Szapary, and S. Stoney Simons, Jr.: Modulation of Induction Properties of Glucocorticoid Receptor-Agonist and -Antagonist Complexes by Coactivators Involves Binding to Receptors but Is Independent of Ability of Coactivators to Augment Transactivation
J. Biol. Chem. 2002 277: 49256-49266. First Published on October 9, 2002; 10.1074/jbc.M205536200 [Abstract] [Full Text] [PDF]

Eric Raspè, Gisèle Mautino, Caroline Duval, Coralie Fontaine, Hélène Duez, Olivier Barbier, Didier Monte, Jamila Fruchart, Jean-Charles Fruchart, and Bart Staels: Transcriptional Regulation of Human Rev-erb $alpha$ Gene Expression by the Orphan Nuclear Receptor Retinoic Acid-related Orphan Receptor $alpha$
J. Biol. Chem. 2002 277: 49275-49281. First Published on October 10, 2002; 10.1074/jbc.M206215200 [Abstract] [Full Text] [PDF]

Katarzyna Cieslik, Ying Zhu, and Kenneth K. Wu: Salicylate Suppresses Macrophage Nitric-oxide Synthase-2 and Cyclo-oxygenase-2 Expression by Inhibiting CCAAT/Enhancer-binding Protein- $beta$ Binding via a Common Signaling Pathway
J. Biol. Chem. 2002 277: 49304-49310. First Published on October 11, 2002; 10.1074/jbc.M205030200 [Abstract] [Full Text] [PDF]

Danielle R. Mercatante, James L. Mohler, and Ryszard Kole: Cellular Response to an Antisense-mediated Shift of Bcl-x Pre-mRNA Splicing and Antineoplastic Agents
J. Biol. Chem. 2002 277: 49374-49382. First Published on October 14, 2002; 10.1074/jbc.M209236200 [Abstract] [Full Text] [PDF]

Alexandre Caillaud, Arun Prakash, Eric Smith, Atsuko Masumi, Ara G. Hovanessian, David E. Levy, and Isabelle Marié: Acetylation of Interferon Regulatory Factor-7 by p300/CREB-binding Protein (CBP)-associated Factor (PCAF) Impairs its DNA Binding
J. Biol. Chem. 2002 277: 49417-49421. First Published on October 8, 2002; 10.1074/jbc.M207484200 [Abstract] [Full Text] [PDF]

Isabelle Lemasson, Nicholas J. Polakowski, Paul J. Laybourn, and Jennifer K. Nyborg: Transcription Factor Binding and Histone Modifications on the Integrated Proviral Promoter in Human T-cell Leukemia Virus-I-infected T-cells
J. Biol. Chem. 2002 277: 49459-49465. First Published on October 16, 2002; 10.1074/jbc.M209566200 [Abstract] [Full Text] [PDF]

Rajnikant Mishra, Ivan P. Gorlov, Lian Y. Chao, Sanjaya Singh, and Grady F. Saunders: PAX6, Paired Domain Influences Sequence Recognition by the Homeodomain
J. Biol. Chem. 2002 277: 49488-49494. First Published on October 17, 2002; 10.1074/jbc.M206478200 [Abstract] [Full Text] [PDF]

Shivalingappa K. Swamynathan and Joram Piatigorsky: Orientation-dependent Influence of an Intergenic Enhancer on the Promoter Activity of the Divergently Transcribed Mouse Shsp/ $alpha$ B-crystallin and Mkbp/HspB2 Genes
J. Biol. Chem. 2002 277: 49700-49706. First Published on October 25, 2002; 10.1074/jbc.M209700200 [Abstract] [Full Text] [PDF]

Kohsuke Kataoka, Song-iee Han, Setsuko Shioda, Momoki Hirai, Makoto Nishizawa, and Hiroshi Handa: MafA Is a Glucose-regulated and Pancreatic $beta$ -Cell-specific Transcriptional Activator for the Insulin Gene
J. Biol. Chem. 2002 277: 49903-49910. First Published on October 3, 2002; 10.1074/jbc.M206796200 [Abstract] [Full Text] [PDF]

Chenchou Yu, Kuofeng Shen, Meiyao Lin, Porchun Chen, Chenchen Lin, Geen-Dong Chang, and Hungwen Chen: GCMa Regulates the Syncytin-mediated Trophoblastic Fusion
J. Biol. Chem. 2002 277: 50062-50068. First Published on October 22, 2002; 10.1074/jbc.M209316200 [Abstract] [Full Text] [PDF]

RNA: Structure Metabolism and Catalysis:

Stephanie J. Muh, Ruben H. Hovhannisyan, and Russ P. Carstens: A Non-sequence-specific Double-stranded RNA Structural Element Regulates Splicing of Two Mutually Exclusive Exons of Fibroblast Growth Factor Receptor 2 (FGFR2)
J. Biol. Chem. 2002 277: 50143-50154. First Published on October 21, 2002; 10.1074/jbc.M207409200 [Abstract] [Full Text] [PDF]

Yuhong Zuo and Murray P. Deutscher: Mechanism of Action of RNase T. I. IDENTIFICATION OF RESIDUES REQUIRED FOR CATALYSIS, SUBSTRATE BINDING, AND DIMERIZATION
J. Biol. Chem. 2002 277: 50155-50159. First Published on October 2, 2002; 10.1074/jbc.M207706200 [Abstract] [Full Text] [PDF]

Yuhong Zuo and Murray P. Deutscher: Mechanism of Action of RNase T. II. A STRUCTURAL AND FUNCTIONAL MODEL OF THE ENZYME
J. Biol. Chem. 2002 277: 50160-50164. First Published on October 2, 2002; 10.1074/jbc.M207707200 [Abstract] [Full Text] [PDF]

Protein Synthesis Post-Translation Modification and Degradation:

Konstantinos Stamatakis, Eva Cernuda-Morollón, Octavio Hernández-Perera, and Dolores Pérez-Sala: Isoprenylation of RhoB Is Necessary for Its Degradation. A NOVEL DETERMINANT IN THE COMPLEX REGULATION OF RhoB EXPRESSION BY THE MEVALONATE PATHWAY
J. Biol. Chem. 2002 277: 49389-49396. First Published on October 15, 2002; 10.1074/jbc.M204049200 [Abstract] [Full Text] [PDF]

Katrin Stade, Frank Vogel, Ingrid Schwienhorst, Birgit Meusser, Corinna Volkwein, Brigitte Nentwig, R. Jürgen Dohmen, and Thomas Sommer: A Lack of SUMO Conjugation Affects cNLS-dependent Nuclear Protein Import in Yeast
J. Biol. Chem. 2002 277: 49554-49561. First Published on October 18, 2002; 10.1074/jbc.M207991200 [Abstract] [Full Text] [PDF]

Katsuhiko Nakashima, Teruki Hagiwara, and Michiyuki Yamada: Nuclear Localization of Peptidylarginine Deiminase V and Histone Deimination in Granulocytes
J. Biol. Chem. 2002 277: 49562-49568. First Published on October 18, 2002; 10.1074/jbc.M208795200 [Abstract] [Full Text] [PDF]

Galyna Sidyelyeva and Lloyd D. Fricker: Characterization of Drosophila Carboxypeptidase D
J. Biol. Chem. 2002 277: 49613-49620. First Published on October 21, 2002; 10.1074/jbc.M209652200 [Abstract] [Full Text] [PDF]

James C. Badciong and Arthur L. Haas: MdmX Is a RING Finger Ubiquitin Ligase Capable of Synergistically Enhancing Mdm2 Ubiquitination
J. Biol. Chem. 2002 277: 49668-49675. First Published on October 21, 2002; 10.1074/jbc.M208593200 [Abstract] [Full Text] [PDF]

Doo Yeon Kim, Laura A. MacKenzie Ingano, and Dora M. Kovacs: Nectin-1 $alpha$ , an Immunoglobulin-like Receptor Involved in the Formation of Synapses, Is a Substrate for Presenilin/ $gamma$ -Secretase-like Cleavage
J. Biol. Chem. 2002 277: 49976-49981. First Published on October 9, 2002; 10.1074/jbc.M210179200 [Abstract] [Full Text] [PDF]

Xin Hua Liu, Alexander Kirschenbaum, Min Lu, Shen Yao, Amy Dosoretz, James F. Holland, and Alice C. Levine: Prostaglandin E₂ Induces Hypoxia-inducible Factor-1 $alpha$ Stabilization and Nuclear Localization in a Human Prostate Cancer Cell Line
J. Biol. Chem. 2002 277: 50081-50086. First Published on October 24, 2002; 10.1074/jbc.M201095200 [Abstract] [Full Text] [PDF]

Yasuhiro Miyauchi, Satomi Yogosawa, Reiko Honda, Tamotsu Nishida, and Hideyo Yasuda: Sumoylation of Mdm2 by Protein Inhibitor of Activated STAT (PIAS) and RanBP2 Enzymes
J. Biol. Chem. 2002 277: 50131-50136. First Published on October 18, 2002; 10.1074/jbc.M208319200 [Abstract] [Full Text] [PDF]

Genomics Proteomics and Bioinformatics:

Joerg F. Schlaak, Catharien M. U. Hilkens, Ana P. Costa-Pereira, Birgit Strobl, Fritz Aberger, Anna-Maria Frischauf, and Ian M. Kerr: Cell-type and Donor-specific Transcriptional Responses to Interferon- $alpha$ . USE OF CUSTOMIZED GENE ARRAYS
J. Biol. Chem. 2002 277: 49428-49437. First Published on October 16, 2002; 10.1074/jbc.M205571200 [Abstract] [Full Text] [PDF] Supplemental Data

Takehiko Sahara, Takako Goda, and Satoru Ohgiya: Comprehensive Expression Analysis of Time-dependent Genetic Responses in Yeast Cells to Low Temperature
J. Biol. Chem. 2002 277: 50015-50021. First Published on October 11, 2002; 10.1074/jbc.M209258200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Suat Özbek, Olivier Pertz, Martine Schwager, Ariel Lustig, Thomas Holstein, and Jürgen Engel: Structure/Function Relationships in the Minicollagen of Hydra Nematocysts
J. Biol. Chem. 2002 277: 49200-49204. First Published on October 3, 2002; 10.1074/jbc.M209401200 [Abstract] [Full Text] [PDF]

Guilherme D. Brand, José Roberto S. A. Leite, Luciano P. Silva, Sérgio Albuquerque, Maura V. Prates, Ricardo B. Azevedo, Vanessa Carregaro, João S. Silva, Vanuza C. L. Sá, Reuber A. Brandão, and Carlos Bloch, Jr.: Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta. ANTI-TRYPANOSOMA CRUZI ACTIVITY WITHOUT CYTOTOXICITY TO MAMMALIAN CELLS
J. Biol. Chem. 2002 277: 49332-49340. First Published on October 11, 2002; 10.1074/jbc.M209289200 [Abstract] [Full Text] [PDF]

Anat Peres Ben-Zvi and Pierre Goloubinoff: Proteinaceous Infectious Behavior in Non-pathogenic Proteins Is Controlled by Molecular Chaperones
J. Biol. Chem. 2002 277: 49422-49427. First Published on October 10, 2002; 10.1074/jbc.M209163200 [Abstract] [Full Text] [PDF]

Srikumar M. Raja, Baikun Wang, Mandakini Dantuluri, Umesh R. Desai, Borries Demeler, Katharina Spiegel, Sunil S. Metkar, and Christopher J. Froelich: Cytotoxic Cell Granule-mediated Apoptosis. CHARACTERIZATION OF THE MACROMOLECULAR COMPLEX OF GRANZYME B WITH SERGLYCIN
J. Biol. Chem. 2002 277: 49523-49530. First Published on October 17, 2002; 10.1074/jbc.M209607200 [Abstract] [Full Text] [PDF]

Arja Pasternack, Sarah K. Coleman, Annukka Jouppila, David G. Mottershead, Maria Lindfors, Michael Pasternack, and Kari Keinänen: $alpha$ -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Channels Lacking the N-terminal Domain
J. Biol. Chem. 2002 277: 49662-49667. First Published on October 21, 2002; 10.1074/jbc.M208349200 [Abstract] [Full Text] [PDF]

Agueda Rostagno, Tamas Revesz, Tammaryn Lashley, Yasushi Tomidokoro, Laura Magnotti, Hans Braendgaard, Gordon Plant, Marie Bojsen-Møller, Janice Holton, Blas Frangione, and Jorge Ghiso: Complement Activation in Chromosome 13 Dementias. SIMILARITIES WITH ALZHEIMER'S DISEASE
J. Biol. Chem. 2002 277: 49782-49790. First Published on October 17, 2002; 10.1074/jbc.M206448200 [Abstract] [Full Text] [PDF]

Andrey V. Kajava: What Curves $alpha$ -Solenoids? EVIDENCE FOR AN $alpha$ -HELICAL TOROID STRUCTURE OF Rpn1 AND Rpn2 PROTEINS OF THE 26 S PROTEASOME
J. Biol. Chem. 2002 277: 49791-49798. First Published on September 20, 2002; 10.1074/jbc.M204982200 [Abstract] [Full Text] [PDF]

Marie-Hélène Le Du and José Luis Millán: Structural Evidence of Functional Divergence in Human Alkaline Phosphatases
J. Biol. Chem. 2002 277: 49808-49814. First Published on October 7, 2002; 10.1074/jbc.M207394200 [Abstract] [Full Text] [PDF]

Se Bok Jang, Yeon-Gil Kim, Yong-Soon Cho, Pann-Ghill Suh, Kyung-Hwa Kim, and Byung-Ha Oh: Crystal Structure of SEDL and Its Implications for a Genetic Disease Spondyloepiphyseal Dysplasia Tarda
J. Biol. Chem. 2002 277: 49863-49869. First Published on October 1, 2002; 10.1074/jbc.M207436200 [Abstract] [Full Text] [PDF]

Nathalie Boulanger, Rebecca J. L. Munks, Joanne V. Hamilton, Françoise Vovelle, Reto Brun, Mike J. Lehane, and Philippe Bulet: Epithelial Innate Immunity. A NOVEL ANTIMICROBIAL PEPTIDE WITH ANTIPARASITIC ACTIVITY IN THE BLOOD-SUCKING INSECT STOMOXYS CALCITRANS
J. Biol. Chem. 2002 277: 49921-49926. First Published on October 7, 2002; 10.1074/jbc.M206296200 [Abstract] [Full Text] [PDF]

Mårten Steen, Bruno O. Villoutreix, Eva A. Norstrøm, Tomio Yamazaki, and Björn Dahlbäck: Defining the Factor Xa-binding Site on Factor Va by Site-directed Glycosylation
J. Biol. Chem. 2002 277: 50022-50029. First Published on October 15, 2002; 10.1074/jbc.M205609200 [Abstract] [Full Text] [PDF]

Gregory W. Sawyer, David C. Chiara, Richard W. Olsen, and Jonathan B. Cohen: Identification of the Bovine $gamma$ -Aminobutyric Acid Type A Receptor $alpha$ Subunit Residues Photolabeled by the Imidazobenzodiazepine [³H]Ro15-4513
J. Biol. Chem. 2002 277: 50036-50045. First Published on October 17, 2002; 10.1074/jbc.M209281200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Yuchen Ma, Tsvika Greener, Michael E. Pacold, Shivani Kaushal, Lois E. Greene, and Evan Eisenberg: Identification of Domain Required for Catalytic Activity of Auxilin in Supporting Clathrin Uncoating by Hsc70
J. Biol. Chem. 2002 277: 49267-49274. First Published on October 10, 2002; 10.1074/jbc.M203695200 [Abstract] [Full Text] [PDF]

William B. Greenleaf and David N. Silverman: Activation of the Proton Transfer Pathway in Catalysis by Iron Superoxide Dismutase
J. Biol. Chem. 2002 277: 49282-49286. First Published on October 10, 2002; 10.1074/jbc.M208629200 [Abstract] [Full Text] [PDF]

Hiroshi Sumichika, Kei Sakata, Noriko Sato, Sanae Takeshita, Seigo Ishibuchi, Mitsuharu Nakamura, Takao Kamahori, Syuji Ehara, Katsuhiko Itoh, Tatsuyuki Ohtsuka, Tomoko Ohbora, Tadashi Mishina, Hirotsugu Komatsu, and Yoichi Naka: Identification of a Potent and Orally Active Non-peptide C5a Receptor Antagonist
J. Biol. Chem. 2002 277: 49403-49407. First Published on October 15, 2002; 10.1074/jbc.M209672200 [Abstract] [Full Text] [PDF]

Yi Yang, Matthew Z. Dieter, Ying Chen, Howard G. Shertzer, Daniel W. Nebert, and Timothy P. Dalton: Initial Characterization of the Glutamate-Cysteine Ligase Modifier Subunit Gclm( $-$ / $-$ ) Knockout Mouse. NOVEL MODEL SYSTEM FOR A SEVERELY COMPROMISED OXIDATIVE STRESS RESPONSE
J. Biol. Chem. 2002 277: 49446-49452. First Published on October 15, 2002; 10.1074/jbc.M209372200 [Abstract] [Full Text] [PDF]

Stuart M. Pitson, Paul A. B. Moretti, Julia R. Zebol, Reza Zareie, Claudia K. Derian, Andrew L. Darrow, Jenson Qi, Richard J. D'Andrea, Christopher J. Bagley, Mathew A. Vadas, and Binks W. Wattenberg: The Nucleotide-binding Site of Human Sphingosine Kinase 1
J. Biol. Chem. 2002 277: 49545-49553. First Published on October 18, 2002; 10.1074/jbc.M206687200 [Abstract] [Full Text] [PDF]

John J. Caterina, Ziedonis Skobe, Joanne Shi, Yanli Ding, James P. Simmer, Henning Birkedal-Hansen, and John D. Bartlett: Enamelysin (Matrix Metalloproteinase 20)-deficient Mice Display an Amelogenesis Imperfecta Phenotype
J. Biol. Chem. 2002 277: 49598-49604. First Published on October 21, 2002; 10.1074/jbc.M209100200 [Abstract] [Full Text] [PDF]

Henri-Pierre Fierobe, Edward A. Bayer, Chantal Tardif, Mirjam Czjzek, Adva Mechaly, Anne Bélaïch, Raphael Lamed, Yuval Shoham, and Jean-Pierre Bélaïch: Degradation of Cellulose Substrates by Cellulosome Chimeras. SUBSTRATE TARGETING VERSUS PROXIMITY OF ENZYME COMPONENTS
J. Biol. Chem. 2002 277: 49621-49630. First Published on October 22, 2002; 10.1074/jbc.M207672200 [Abstract] [Full Text] [PDF]

Xiaohong Zhu, Guiliang Tang, and Gad Galili: The Activity of the Arabidopsis Bifunctional Lysine-ketoglutarate Reductase/Saccharopine Dehydrogenase Enzyme of Lysine Catabolism Is Regulated by Functional Interaction between Its Two Enzyme Domains
J. Biol. Chem. 2002 277: 49655-49661. First Published on October 21, 2002; 10.1074/jbc.M205466200 [Abstract] [Full Text] [PDF]

Chunbo Qin, Cunxi Wang, and Xuemin Wang: Kinetic Analysis of Arabidopsis Phospholipase D $delta$ . SUBSTRATE PREFERENCE AND MECHANISM OF ACTIVATION BY Ca²⁺ AND PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE
J. Biol. Chem. 2002 277: 49685-49690. First Published on October 22, 2002; 10.1074/jbc.M209598200 [Abstract] [Full Text] [PDF]

Guido Capitani, Darla L. McCarthy, Heinz Gut, Markus G. Grütter, and Jack F. Kirsch: Apple 1-Aminocyclopropane-1-carboxylate Synthase in Complex with the Inhibitor L-Aminoethoxyvinylglycine. EVIDENCE FOR A KETIMINE INTERMEDIATE
J. Biol. Chem. 2002 277: 49735-49742. First Published on September 11, 2002; 10.1074/jbc.M208427200 [Abstract] [Full Text] [PDF]

Robin S. Chan, Jessica B. Sakash, Christine P. Macol, Jay M. West, Hiro Tsuruta, and Evan R. Kantrowitz: The Role of Intersubunit Interactions for the Stabilization of the T State of Escherichia coli Aspartate Transcarbamoylase
J. Biol. Chem. 2002 277: 49755-49760. First Published on October 23, 2002; 10.1074/jbc.M208919200 [Abstract] [Full Text] [PDF]

David M. Keller and Hua Lu: p53 Serine 392 Phosphorylation Increases after UV through Induction of the Assembly of the CK2·hSPT16·SSRP1 Complex
J. Biol. Chem. 2002 277: 50206-50213. First Published on October 21, 2002; 10.1074/jbc.M209820200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Yann Saint-Georges, Nathalie Bonnefoy, Jean Paul di Rago, Stephane Chiron, and Geneviève Dujardin: A Pathogenic Cytochrome b Mutation Reveals New Interactions between Subunits of the Mitochondrial bc1 Complex
J. Biol. Chem. 2002 277: 49397-49402. First Published on October 15, 2002; 10.1074/jbc.M207219200 [Abstract] [Full Text] [PDF]

Marc S. Pittman, Hazel Corker, Guanghui Wu, Marie B. Binet, Arthur J. G. Moir, and Robert K. Poole: Cysteine Is Exported from the Escherichia coli Cytoplasm by CydDC, an ATP-binding Cassette-type Transporter Required for Cytochrome Assembly
J. Biol. Chem. 2002 277: 49841-49849. First Published on October 21, 2002; 10.1074/jbc.M205615200 [Abstract] [Full Text] [PDF]

James P. Willcocks, Peter J. Mulquiney, J. Clive Ellory, Richard L. Veech, George K. Radda, and Kieran Clarke: Simultaneous Determination of Low Free Mg²⁺ and pH in Human Sickle Cells using ³¹P NMR Spectroscopy
J. Biol. Chem. 2002 277: 49911-49920. First Published on September 23, 2002; 10.1074/jbc.M207551200 [Abstract] [Full Text] [PDF] Supplemental Data

Athanasios Paschos, Anette Bauer, Anja Zimmermann, Eva Zehelein, and August Böck: HypF, a Carbamoyl Phosphate-converting Enzyme Involved in [NiFe] Hydrogenase Maturation
J. Biol. Chem. 2002 277: 49945-49951. First Published on October 10, 2002; 10.1074/jbc.M204601200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Charlotte Wiberg, Dick Heinegård, Christina Wenglén, Rupert Timpl, and Matthias Mörgelin: Biglycan Organizes Collagen VI into Hexagonal-like Networks Resembling Tissue Structures
J. Biol. Chem. 2002 277: 49120-49126. First Published on September 26, 2002; 10.1074/jbc.M206891200 [Abstract] [Full Text] [PDF]

John F. Cipollo, Catherine E. Costello, and Carlos B. Hirschberg: The Fine Structure of Caenorhabditis elegans N-Glycans
J. Biol. Chem. 2002 277: 49143-49157. First Published on October 1, 2002; 10.1074/jbc.M208020200 [Abstract] [Full Text] [PDF] Supplemental Data

Megumi Morimoto-Tomita, Kenji Uchimura, Zena Werb, Stefan Hemmerich, and Steven D. Rosen: Cloning and Characterization of Two Extracellular Heparin-degrading Endosulfatases in Mice and Humans
J. Biol. Chem. 2002 277: 49175-49185. First Published on October 3, 2002; 10.1074/jbc.M205131200 [Abstract] [Full Text] [PDF]

Camilla Westling and Ulf Lindahl: Location of N-Unsubstituted Glucosamine Residues in Heparan Sulfate
J. Biol. Chem. 2002 277: 49247-49255. First Published on October 8, 2002; 10.1074/jbc.M209139200 [Abstract] [Full Text] [PDF]

Tomomi Hirosaki, Yoshiaki Tsubota, Yoshinobu Kariya, Kayano Moriyama, Hiroto Mizushima, and Kaoru Miyazaki: Laminin-6 Is Activated by Proteolytic Processing and Regulates Cellular Adhesion and Migration Differently from Laminin-5
J. Biol. Chem. 2002 277: 49287-49295. First Published on October 11, 2002; 10.1074/jbc.M111096200 [Abstract] [Full Text] [PDF]

John R. Couchman, Susan Vogt, Ssang-Taek Lim, Yangmi Lim, Eok-Soo Oh, Glenn D. Prestwich, Anne Theibert, Weontae Lee, and Anne Woods: Regulation of Inositol Phospholipid Binding and Signaling through Syndecan-4
J. Biol. Chem. 2002 277: 49296-49303. First Published on October 10, 2002; 10.1074/jbc.M209679200 [Abstract] [Full Text] [PDF]

Ki-Young Lee, Hyung Gu Kim, Mi Ran Hwang, Jung Il Chae, Jai Myung Yang, Young Choon Lee, Young Kug Choo, Young Ik Lee, Sang-Soo Lee, and Su-Il Do: The Hexapeptide Inhibitor of Gal $beta$ 1,3GalNAc-specific $alpha$ 2,3-Sialyltransferase as a Generic Inhibitor of Sialyltransferases
J. Biol. Chem. 2002 277: 49341-49351. First Published on October 11, 2002; 10.1074/jbc.M209618200 [Abstract] [Full Text] [PDF]

Barry M. Steiglitz, Douglas R. Keene, and Daniel S. Greenspan: PCOLCE2 Encodes a Functional Procollagen C-Proteinase Enhancer (PCPE2) That Is a Collagen-binding Protein Differing in Distribution of Expression and Post-translational Modification from the Previously Described PCPE1
J. Biol. Chem. 2002 277: 49820-49830. First Published on October 20, 2002; 10.1074/jbc.M209891200 [Abstract] [Full Text] [PDF]

Thomas A. Gerken, Jiexin Zhang, Jessica Levine, and Åke Elhammer: Mucin Core O-Glycosylation Is Modulated by Neighboring Residue Glycosylation Status. KINETIC MODELING OF THE SITE-SPECIFIC GLYCOSYLATION OF THE APO-PORCINE SUBMAXILLARY MUCIN TANDEM REPEAT BY UDP-GalNAc:POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASES T1 AND T2
J. Biol. Chem. 2002 277: 49850-49862. First Published on October 22, 2002; 10.1074/jbc.M205851200 [Abstract] [Full Text] [PDF] Supplemental Data

Raquel París, Albert Morales, Olga Coll, Alberto Sánchez-Reyes, Carmen García-Ruiz, and José C. Fernández-Checa: Ganglioside GD3 Sensitizes Human Hepatoma Cells to Cancer Therapy
J. Biol. Chem. 2002 277: 49870-49876. First Published on September 25, 2002; 10.1074/jbc.M208303200 [Abstract] [Full Text] [PDF]

Tunhan Chang, Kenneth G. Milne, Maria Lucia Sampaio Güther, Terry K. Smith, and Michael A. J. Ferguson: Cloning of Trypanosoma brucei and Leishmania major Genes Encoding the GlcNAc-Phosphatidylinositol De-N-acetylase of Glycosylphosphatidylinositol Biosynthesis That Is Essential to the African Sleeping Sickness Parasite
J. Biol. Chem. 2002 277: 50176-50182. First Published on October 2, 2002; 10.1074/jbc.M208374200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Stuart J. Rabin, Alessia Bachis, and Italo Mocchetti: Gangliosides Activate Trk Receptors by Inducing the Release of Neurotrophins
J. Biol. Chem. 2002 277: 49466-49472. First Published on October 17, 2002; 10.1074/jbc.M203240200 [Abstract] [Full Text] [PDF]

Vidya V. Kunjathoor, Maria Febbraio, Eugene A. Podrez, Kathryn J. Moore, Lorna Andersson, Stephanie Koehn, Jeongmi S. Rhee, Roy Silverstein, Henry F. Hoff, and Mason W. Freeman: Scavenger Receptors Class A-I/II and CD36 Are the Principal Receptors Responsible for the Uptake of Modified Low Density Lipoprotein Leading to Lipid Loading in Macrophages
J. Biol. Chem. 2002 277: 49982-49988. First Published on October 9, 2002; 10.1074/jbc.M209649200 [Abstract] [Full Text] [PDF]

Membrane Transport Structure Function and Biogenesis:

Donald N. Cullis, Betsey Philip, James D. Baleja, and Larry A. Feig: Rab11-FIP2, an Adaptor Protein Connecting Cellular Components Involved in Internalization and Recycling of Epidermal Growth Factor Receptors
J. Biol. Chem. 2002 277: 49158-49166. First Published on October 2, 2002; 10.1074/jbc.M206316200 [Abstract] [Full Text] [PDF]

John J. Enyeart, Lin Xu, Sanjay Danthi, and Judith A. Enyeart: An ACTH- and ATP-regulated Background K⁺ Channel in Adrenocortical Cells Is TREK-1
J. Biol. Chem. 2002 277: 49186-49199. First Published on October 3, 2002; 10.1074/jbc.M207233200 [Abstract] [Full Text] [PDF]

Gerardo De Blas, Marcela Michaut, Claudia L. Treviño, Claudia N. Tomes, Roberto Yunes, Alberto Darszon, and Luis S. Mayorga: The Intraacrosomal Calcium Pool Plays a Direct Role in Acrosomal Exocytosis
J. Biol. Chem. 2002 277: 49326-49331. First Published on October 11, 2002; 10.1074/jbc.M208587200 [Abstract] [Full Text] [PDF]

Ke Dong, LieQi Tang, Gordon G. MacGregor, and Steven C. Hebert: Localization of the ATP/Phosphatidylinositol 4,5 Diphosphate-binding Site to a 39-Amino Acid Region of the Carboxyl Terminus of the ATP-regulated K⁺ Channel Kir1.1
J. Biol. Chem. 2002 277: 49366-49373. First Published on October 14, 2002; 10.1074/jbc.M208679200 [Abstract] [Full Text] [PDF]

Koji Koike, Curtis J. Oleschuk, Anass Haimeur, Sharon L. Olsen, Roger G. Deeley, and Susan P. C. Cole: Multiple Membrane-associated Tryptophan Residues Contribute to the Transport Activity and Substrate Specificity of the Human Multidrug Resistance Protein, MRP1
J. Biol. Chem. 2002 277: 49495-49503. First Published on October 17, 2002; 10.1074/jbc.M206896200 [Abstract] [Full Text] [PDF]

Reika Watanabe, Kouichi Funato, Krishnan Venkataraman, Anthony H. Futerman, and Howard Riezman: Sphingolipids Are Required for the Stable Membrane Association of Glycosylphosphatidylinositol-anchored Proteins in Yeast
J. Biol. Chem. 2002 277: 49538-49544. First Published on October 18, 2002; 10.1074/jbc.M206209200 [Abstract] [Full Text] [PDF]

Georgiy A. Belogurov and Reijo Lahti: A Lysine Substitute for K⁺. A460K MUTATION ELIMINATES K⁺ DEPENDENCE IN H⁺-PYROPHOSPHATASE OF CARBOXYDOTHERMUS HYDROGENOFORMANS
J. Biol. Chem. 2002 277: 49651-49654. First Published on October 24, 2002; 10.1074/jbc.M210341200 [Abstract] [Full Text] [PDF]

Luke H. Chamberlain and Gwyn W. Gould: The Vesicle- and Target-SNARE Proteins That Mediate Glut4 Vesicle Fusion Are Localized in Detergent-insoluble Lipid Rafts Present on Distinct Intracellular Membranes
J. Biol. Chem. 2002 277: 49750-49754. First Published on October 9, 2002; 10.1074/jbc.M206936200 [Abstract] [Full Text] [PDF]

Hanbang Zhang, Ellen M. Howard, and Paul D. Roepe: Analysis of the Antimalarial Drug Resistance Protein Pfcrt Expressed in Yeast
J. Biol. Chem. 2002 277: 49767-49775. First Published on September 25, 2002; 10.1074/jbc.M204005200 [Abstract] [Full Text] [PDF]

Krisztina Peter, Karoly Varga, Zsuzsa Bebok, Carmel M. McNicholas-Bevensee, Lisa Schwiebert, Eric J. Sorscher, Erik M. Schwiebert, and James F. Collawn: Ablation of Internalization Signals in the Carboxyl-terminal Tail of the Cystic Fibrosis Transmembrane Conductance Regulator Enhances Cell Surface Expression
J. Biol. Chem. 2002 277: 49952-49957. First Published on October 9, 2002; 10.1074/jbc.M209275200 [Abstract] [Full Text] [PDF]

Serhan Karvar, Xuebiao Yao, James M. Crothers, Jr., Yuechueng Liu, and John G. Forte: Localization and Function of Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein-25 and Vesicle-associated Membrane Protein-2 in Functioning Gastric Parietal Cells
J. Biol. Chem. 2002 277: 50030-50035. First Published on October 16, 2002; 10.1074/jbc.M207694200 [Abstract] [Full Text] [PDF]

Rajgopal Govindarajan, Sumin Zhao, Xiao-Hong Song, Rong-Jun Guo, Margaret Wheelock, Keith R. Johnson, and Parmender P. Mehta: Impaired Trafficking of Connexins in Androgen-independent Human Prostate Cancer Cell Lines and Its Mitigation by $alpha$ -Catenin
J. Biol. Chem. 2002 277: 50087-50097. First Published on August 29, 2002; 10.1074/jbc.M202652200 [Abstract] [Full Text] [PDF]

Shaohu Sheng, Clint J. Perry, and Thomas R. Kleyman: External Nickel Inhibits Epithelial Sodium Channel by Binding to Histidine Residues within the Extracellular Domains of $alpha$ and $gamma$ Subunits and Reducing Channel Open Probability
J. Biol. Chem. 2002 277: 50098-50111. First Published on October 22, 2002; 10.1074/jbc.M209975200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Wei Chen, Michael A. White, and Melanie H. Cobb: Stimulus-specific Requirements for MAP3 Kinases in Activating the JNK Pathway
J. Biol. Chem. 2002 277: 49105-49110. First Published on September 25, 2002; 10.1074/jbc.M204934200 [Abstract] [Full Text] [PDF]

Jon Schoorlemmer and Mitchell Goldfarb: Fibroblast Growth Factor Homologous Factors and the Islet Brain-2 Scaffold Protein Regulate Activation of a Stress-activated Protein Kinase
J. Biol. Chem. 2002 277: 49111-49119. First Published on September 18, 2002; 10.1074/jbc.M205520200 [Abstract] [Full Text] [PDF]

Amandine Hurbin, Laurence Dubrez, Jean-Luc Coll, and Marie-Christine Favrot: Inhibition of Apoptosis by Amphiregulin via an Insulin-like Growth Factor-1 Receptor-dependent Pathway in Non-small Cell Lung Cancer Cell Lines
J. Biol. Chem. 2002 277: 49127-49133. First Published on September 27, 2002; 10.1074/jbc.M207584200 [Abstract] [Full Text] [PDF]

Veronica Novotny-Diermayr, Tong Zhang, Lei Gu, and Xinmin Cao: Protein Kinase C $delta$ Associates with the Interleukin-6 Receptor Subunit Glycoprotein (gp) 130 via Stat3 and Enhances Stat3-gp130 Interaction
J. Biol. Chem. 2002 277: 49134-49142. First Published on October 1, 2002; 10.1074/jbc.M206727200 [Abstract] [Full Text] [PDF]

Rao V. L. Papineni, Kristen M. S. O'Connell, Hongwei Zhang, Robert T. Dirksen, and Susan L. Hamilton: Suramin Interacts with the Calmodulin Binding Site on the Ryanodine Receptor, RYR1
J. Biol. Chem. 2002 277: 49167-49174. First Published on October 2, 2002; 10.1074/jbc.M209564200 [Abstract] [Full Text] [PDF]

Elizabeth K. Brint, Katherine A. Fitzgerald, Philip Smith, Anthony J. Coyle, Jose-Carlos Gutierrez-Ramos, Padraic G. Fallon, and Luke A. J. O'Neill: Characterization of Signaling Pathways Activated by the Interleukin 1 (IL-1) Receptor Homologue T1/ST2. A ROLE FOR JUN N-TERMINAL KINASE IN IL-4 INDUCTION
J. Biol. Chem. 2002 277: 49205-49211. First Published on October 3, 2002; 10.1074/jbc.M209685200 [Abstract] [Full Text] [PDF]

David Gilot, Pascal Loyer, Anne Corlu, Denise Glaise, Dominique Lagadic-Gossmann, Azeddine Atfi, Fabrice Morel, Hidenori Ichijo, and Christiane Guguen-Guillouzo: Liver Protection from Apoptosis Requires Both Blockage of Initiator Caspase Activities and Inhibition of ASK1/JNK Pathway via Glutathione S-Transferase Regulation
J. Biol. Chem. 2002 277: 49220-49229. First Published on October 4, 2002; 10.1074/jbc.M207325200 [Abstract] [Full Text] [PDF]

Chuan-Min Hu, So Young Jang, Jessica C. Fanzo, and Alessandra B. Pernis: Modulation of T Cell Cytokine Production by Interferon Regulatory Factor-4
J. Biol. Chem. 2002 277: 49238-49246. First Published on October 8, 2002; 10.1074/jbc.M205895200 [Abstract] [Full Text] [PDF]

Susanne Idel, Peter Ellinghaus, Christian Wolfrum, Jerzy-Roch Nofer, Jolein Gloerich, Gerd Assmann, Friedrich Spener, and Udo Seedorf: Branched Chain Fatty Acids Induce Nitric Oxide-dependent Apoptosis in Vascular Smooth Muscle Cells
J. Biol. Chem. 2002 277: 49319-49325. First Published on October 3, 2002; 10.1074/jbc.M204639200 [Abstract] [Full Text] [PDF]

Lihong Zhao, Sandra Lobo, Xiangwen Dong, Addison D. Ault, and Robert J. Deschenes: Erf4p and Erf2p Form an Endoplasmic Reticulum-associated Complex Involved in the Plasma Membrane Localization of Yeast Ras Proteins
J. Biol. Chem. 2002 277: 49352-49359. First Published on October 11, 2002; 10.1074/jbc.M209760200 [Abstract] [Full Text] [PDF]

Jiaxu Li, Danesh Moazed, and Steven P. Gygi: Association of the Histone Methyltransferase Set2 with RNA Polymerase II Plays a Role in Transcription Elongation
J. Biol. Chem. 2002 277: 49383-49388. First Published on October 14, 2002; 10.1074/jbc.M209294200 [Abstract] [Full Text] [PDF]

Seunghwan Lim, Yonglong Zou, and Eileen Friedman: The Transcriptional Activator Mirk/Dyrk1B Is Sequestered by p38 $alpha$ / $beta$ MAP Kinase
J. Biol. Chem. 2002 277: 49438-49445. First Published on October 15, 2002; 10.1074/jbc.M206840200 [Abstract] [Full Text] [PDF]

Cyrus B. Munshi, Richard Graeff, and Hon Cheung Lee: Evidence for a Causal Role of CD38 Expression in Granulocytic Differentiation of Human HL-60 Cells
J. Biol. Chem. 2002 277: 49453-49458. First Published on October 16, 2002; 10.1074/jbc.M209313200 [Abstract] [Full Text] [PDF]

Philippe P. Roux, Geneviève Dorval, Mathieu Boudreau, Alexandre Angers-Loustau, Stephen J. Morris, Joe Makkerh, and Philip A. Barker: K252a and CEP1347 Are Neuroprotective Compounds That Inhibit Mixed-lineage Kinase-3 and Induce Activation of Akt and ERK
J. Biol. Chem. 2002 277: 49473-49480. First Published on October 17, 2002; 10.1074/jbc.M203428200 [Abstract] [Full Text] [PDF]

Yan Zhou, Peter H. Larsen, Chunhai Hao, and V. Wee Yong: CXCR4 Is a Major Chemokine Receptor on Glioma Cells and Mediates Their Survival
J. Biol. Chem. 2002 277: 49481-49487. First Published on October 17, 2002; 10.1074/jbc.M206222200 [Abstract] [Full Text] [PDF]

Hege Berghagen, Erlend Ragnhildstveit, Kristin Krogsrud, Gunnar Thuestad, James Apriletti, and Fahri Saatcioglu: Corepressor SMRT Functions as a Coactivator for Thyroid Hormone Receptor T3R $alpha$ from a Negative Hormone Response Element
J. Biol. Chem. 2002 277: 49517-49522. First Published on October 17, 2002; 10.1074/jbc.M209546200 [Abstract] [Full Text] [PDF]

Anat Erdreich-Epstein, Linda B. Tran, Nina N. Bowman, Hongtao Wang, Myles C. Cabot, Donald L. Durden, Jitka Vlckova, C. Patrick Reynolds, Monique F. Stins, Susan Groshen, and Melissa Millard: Ceramide Signaling in Fenretinide-induced Endothelial Cell Apoptosis
J. Biol. Chem. 2002 277: 49531-49537. First Published on October 17, 2002; 10.1074/jbc.M209962200 [Abstract] [Full Text] [PDF]

Marco Tafani, Joshua A. Cohn, Natalie O. Karpinich, Ronald J. Rothman, Matteo A. Russo, and John L. Farber: Regulation of Intracellular pH Mediates Bax Activation in HeLa Cells Treated with Staurosporine or Tumor Necrosis Factor- $alpha$
J. Biol. Chem. 2002 277: 49569-49576. First Published on October 18, 2002; 10.1074/jbc.M208915200 [Abstract] [Full Text] [PDF]

Michal Hetman, Shih-Ling Hsuan, Agata Habas, Matthew J. Higgins, and Zhengui Xia: ERK1/2 Antagonizes Glycogen Synthase Kinase-3 $beta$ -induced Apoptosis in Cortical Neurons
J. Biol. Chem. 2002 277: 49577-49584. First Published on October 21, 2002; 10.1074/jbc.M111227200 [Abstract] [Full Text] [PDF]

Bastiano Sanna, Dana Kramer, and Armando A. Genazzani: The Expression of the PDZ Protein MALS-1/Velis Is Regulated by Calcium and Calcineurin in Cerebellar Granule Cells
J. Biol. Chem. 2002 277: 49585-49590. First Published on October 21, 2002; 10.1074/jbc.M207826200 [Abstract] [Full Text] [PDF]

Hong Wang and David L. Brautigan: A Novel Transmembrane Ser/Thr Kinase Complexes with Protein Phosphatase-1 and Inhibitor-2
J. Biol. Chem. 2002 277: 49605-49612. First Published on October 21, 2002; 10.1074/jbc.M209335200 [Abstract] [Full Text] [PDF]

Xu Chen and Marilyn D. Resh: Cholesterol Depletion from the Plasma Membrane Triggers Ligand-independent Activation of the Epidermal Growth Factor Receptor
J. Biol. Chem. 2002 277: 49631-49637. First Published on October 22, 2002; 10.1074/jbc.M208327200 [Abstract] [Full Text] [PDF]

Qishen Pang, Tracy A. Christianson, Winifred Keeble, Tara Koretsky, and Grover C. Bagby: The Anti-apoptotic Function of Hsp70 in the Interferon-inducible Double-stranded RNA-dependent Protein Kinase-mediated Death Signaling Pathway Requires the Fanconi Anemia Protein, FANCC
J. Biol. Chem. 2002 277: 49638-49643. First Published on October 22, 2002; 10.1074/jbc.M209386200 [Abstract] [Full Text] [PDF]

Christian E. Wrede, Lorna M. Dickson, Melissa K. Lingohr, Isabelle Briaud, and Christopher J. Rhodes: Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic $beta$ -Cells (INS-1)
J. Biol. Chem. 2002 277: 49676-49684. First Published on October 21, 2002; 10.1074/jbc.M208756200 [Abstract] [Full Text] [PDF]

Susanne Miedlich, Lucio Gama, and Gerda E. Breitwieser: Calcium Sensing Receptor Activation by a Calcimimetic Suggests a Link between Cooperativity and Intracellular Calcium Oscillations
J. Biol. Chem. 2002 277: 49691-49699. First Published on October 23, 2002; 10.1074/jbc.M205578200 [Abstract] [Full Text] [PDF]

Elizabeth Buck, Peter Schatz, Suzanne Scarlata, and Ravi Iyengar: Role of Dynamic Interactions in Effective Signal Transfer for G $beta$ Stimulation of Phospholipase C- $beta$ 2
J. Biol. Chem. 2002 277: 49707-49715. First Published on October 17, 2002; 10.1074/jbc.M205553200 [Abstract] [Full Text] [PDF]

Jonathan P. Davis, Jack A. Rall, Peter J. Reiser, Lawrence B. Smillie, and Svetlana B. Tikunova: Engineering Competitive Magnesium Binding into the First EF-hand of Skeletal Troponin C
J. Biol. Chem. 2002 277: 49716-49726. First Published on October 22, 2002; 10.1074/jbc.M208488200 [Abstract] [Full Text] [PDF]

Lotta Johansson Borgius, Knut R. Steffensen, Jan-Åke Gustafsson, and Eckardt Treuter: Glucocorticoid Signaling Is Perturbed by the Atypical Orphan Receptor and Corepressor SHP
J. Biol. Chem. 2002 277: 49761-49766. First Published on September 24, 2002; 10.1074/jbc.M205641200 [Abstract] [Full Text] [PDF]

Joel W. Neal and Neil A. Clipstone: Calcineurin Mediates the Calcium-dependent Inhibition of Adipocyte Differentiation in 3T3-L1 Cells
J. Biol. Chem. 2002 277: 49776-49781. First Published on September 25, 2002; 10.1074/jbc.M207913200 [Abstract] [Full Text] [PDF]

Anat Shirvan, Michal Kimron, Vered Holdengreber, Ilan Ziv, Yehuda Ben-Shaul, Shlomo Melamed, Eldad Melamed, Ari Barzilai, and Arieh S. Solomon: Anti-semaphorin 3A Antibodies Rescue Retinal Ganglion Cells from Cell Death following Optic Nerve Axotomy
J. Biol. Chem. 2002 277: 49799-49807. First Published on October 9, 2002; 10.1074/jbc.M204793200 [Abstract] [Full Text] [PDF]

George Sandusky, David T. Berg, Mark A. Richardson, Laura Myers, and Brian W. Grinnell: Modulation of Thrombomodulin-dependent Activation of Human Protein C through Differential Expression of Endothelial Smads
J. Biol. Chem. 2002 277: 49815-49819. First Published on October 28, 2002; 10.1074/jbc.C200543200 [Abstract] [Full Text] [PDF]

Brett Langley, Mark Thomas, Amy Bishop, Mridula Sharma, Stewart Gilmour, and Ravi Kambadur: Myostatin Inhibits Myoblast Differentiation by Down-regulating MyoD Expression
J. Biol. Chem. 2002 277: 49831-49840. First Published on September 18, 2002; 10.1074/jbc.M204291200 [Abstract] [Full Text] [PDF]

Edward J. Dell, Jennifer Connor, Songhai Chen, Elizabeth G. Stebbins, Nikolai P. Skiba, Daria Mochly-Rosen, and Heidi E. Hamm: The $beta$ $gamma$ Subunit of Heterotrimeric G Proteins Interacts with RACK1 and Two Other WD Repeat Proteins
J. Biol. Chem. 2002 277: 49888-49895. First Published on September 30, 2002; 10.1074/jbc.M202755200 [Abstract] [Full Text] [PDF]

Elisabetta Ciani, Sandra Guidi, Giuliano Della Valle, Giovanni Perini, Renata Bartesaghi, and Antonio Contestabile: Nitric Oxide Protects Neuroblastoma Cells from Apoptosis Induced by Serum Deprivation through cAMP-response Element-binding Protein (CREB) Activation
J. Biol. Chem. 2002 277: 49896-49902. First Published on October 3, 2002; 10.1074/jbc.M206177200 [Abstract] [Full Text] [PDF]

Anjana Saxena, Pavel Morozov, Dale Frank, Raymond Musalo, Mark A. Lemmon, Edward Y. Skolnik, and Benjamin Tycko: Phosphoinositide Binding by the Pleckstrin Homology Domains of Ipl and Tih1
J. Biol. Chem. 2002 277: 49935-49944. First Published on October 8, 2002; 10.1074/jbc.M206497200 [Abstract] [Full Text] [PDF]

Uwe Beffert, Gerardo Morfini, Hans H. Bock, Huichuan Reyna, Scott T. Brady, and Joachim Herz: Reelin-mediated Signaling Locally Regulates Protein Kinase B/Akt and Glycogen Synthase Kinase 3 $beta$
J. Biol. Chem. 2002 277: 49958-49964. First Published on October 9, 2002; 10.1074/jbc.M209205200 [Abstract] [Full Text] [PDF]

Gaelh Ouengue Mbele, Jean Christophe Deloulme, Benoît Jean Gentil, Christian Delphin, Myriam Ferro, Jérôme Garin, Miyoko Takahashi, and Jacques Baudier: The Zinc- and Calcium-binding S100B Interacts and Co-localizes with IQGAP1 during Dynamic Rearrangement of Cell Membranes
J. Biol. Chem. 2002 277: 49998-50007. First Published on October 10, 2002; 10.1074/jbc.M205363200 [Abstract] [Full Text] [PDF]

Hideki Matsui, Yukiko Hikichi, Isamu Tsuji, Takao Yamada, and Yasushi Shintani: LIGHT, a Member of the Tumor Necrosis Factor Ligand Superfamily, Prevents Tumor Necrosis Factor- $alpha$ -mediated Human Primary Hepatocyte Apoptosis, but Not Fas-mediated Apoptosis
J. Biol. Chem. 2002 277: 50054-50061. First Published on October 18, 2002; 10.1074/jbc.M206562200 [Abstract] [Full Text] [PDF]

Maya Groysman, Idit Hornstein, Andres Alcover, and Shulamit Katzav: Vav1 and Ly-GDI Two Regulators of Rho GTPases, Function Cooperatively as Signal Transducers in T Cell Antigen Receptor-induced Pathways
J. Biol. Chem. 2002 277: 50121-50130. First Published on October 16, 2002; 10.1074/jbc.M204299200 [Abstract] [Full Text] [PDF]

Qinghua Zeng, Laurie K. McCauley, and Cun-Yu Wang: Hepatocyte Growth Factor Inhibits Anoikis by Induction of Activator Protein 1-dependent Cyclooxygenase-2. IMPLICATION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA PROGRESSION
J. Biol. Chem. 2002 277: 50137-50142. First Published on October 18, 2002; 10.1074/jbc.M208952200 [Abstract] [Full Text] [PDF]

Johann Sohn, KiSung Ryu, Gail Sievert, MyoungKun Jeoung, Inhae Ji, and Tae H. Ji: Follicle-stimulating Hormone Interacts with Exoloop 3 of the Receptor
J. Biol. Chem. 2002 277: 50165-50175. First Published on October 8, 2002; 10.1074/jbc.M207646200 [Abstract] [Full Text] [PDF]

Simone M. Ward, Jay S. Desgrosellier, Xiaoli Zhuang, Joey V. Barnett, and Jonas B. Galper: Transforming Growth Factor $beta$ (TGF $beta$ ) Signaling via Differential Activation of Activin Receptor-like Kinases 2 and 5 during Cardiac Development. ROLE IN REGULATING PARASYMPATHETIC RESPONSIVENESS
J. Biol. Chem. 2002 277: 50183-50189. First Published on October 21, 2002; 10.1074/jbc.M209668200 [Abstract] [Full Text] [PDF]

Devki Nandan, Taolin Yi, Martin Lopez, Crystal Lai, and Neil E. Reiner: Leishmania EF-1 $alpha$ Activates the Src Homology 2 Domain Containing Tyrosine Phosphatase SHP-1 Leading to Macrophage Deactivation
J. Biol. Chem. 2002 277: 50190-50197. First Published on October 15, 2002; 10.1074/jbc.M209210200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Yue Sun, Zhijie Cheng, Lan Ma, and Gang Pei: $beta$ -Arrestin2 Is Critically Involved in CXCR4-mediated Chemotaxis, and This Is Mediated by Its Enhancement of p38 MAPK Activation
J. Biol. Chem. 2002 277: 49212-49219. First Published on October 4, 2002; 10.1074/jbc.M207294200 [Abstract] [Full Text] [PDF]

Rodrigo Martinez and Flávia Carvalho Alcantara Gomes: Neuritogenesis Induced by Thyroid Hormone-treated Astrocytes Is Mediated by Epidermal Growth Factor/Mitogen-activated Protein Kinase-Phosphatidylinositol 3-Kinase Pathways and Involves Modulation of Extracellular Matrix Proteins
J. Biol. Chem. 2002 277: 49311-49318. First Published on September 27, 2002; 10.1074/jbc.M209284200 [Abstract] [Full Text] [PDF]

Gorka Basañez, Juanita C. Sharpe, Jennifer Galanis, Teresa B. Brandt, J. Marie Hardwick, and Joshua Zimmerberg: Bax-type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature
J. Biol. Chem. 2002 277: 49360-49365. First Published on October 14, 2002; 10.1074/jbc.M206069200 [Abstract] [Full Text] [PDF]

Yumay Chen, Daniel J. Riley, Lei Zheng, Phang-Lang Chen, and Wen-Hwa Lee: Phosphorylation of the Mitotic Regulator Protein Hec1 by Nek2 Kinase Is Essential for Faithful Chromosome Segregation
J. Biol. Chem. 2002 277: 49408-49416. First Published on October 16, 2002; 10.1074/jbc.M207069200 [Abstract] [Full Text] [PDF]

Ji Li, Peili Chen, Natasha Sinogeeva, Myriam Gorospe, Robert P. Wersto, Francis J. Chrest, Janice Barnes, and Yusen Liu: Arsenic Trioxide Promotes Histone H3 Phosphoacetylation at the Chromatin of CASPASE-10 in Acute Promyelocytic Leukemia Cells
J. Biol. Chem. 2002 277: 49504-49510. First Published on October 17, 2002; 10.1074/jbc.M207836200 [Abstract] [Full Text] [PDF]

Subhas C. Biswas and Lloyd A. Greene: Nerve Growth Factor (NGF) Down-regulates the Bcl-2 Homology 3 (BH3) Domain-only Protein Bim and Suppresses Its Proapoptotic Activity by Phosphorylation
J. Biol. Chem. 2002 277: 49511-49516. First Published on October 17, 2002; 10.1074/jbc.M208086200 [Abstract] [Full Text] [PDF]

Catherine A. Wolkow, Manuel J. Muñoz, Donald L. Riddle, and Gary Ruvkun: Insulin Receptor Substrate and p55 Orthologous Adaptor Proteins Function in the Caenorhabditis elegans daf-2/Insulin-like Signaling Pathway
J. Biol. Chem. 2002 277: 49591-49597. First Published on October 18, 2002; 10.1074/jbc.M207866200 [Abstract] [Full Text] [PDF]

Israel Muro, Bruce A. Hay, and Rollie J. Clem: The Drosophila DIAP1 Protein Is Required to Prevent Accumulation of a Continuously Generated, Processed Form of the Apical Caspase DRONC
J. Biol. Chem. 2002 277: 49644-49650. First Published on October 22, 2002; 10.1074/jbc.M203464200 [Abstract] [Full Text] [PDF]

Oyebode Olakanmi, Larry S. Schlesinger, Ambar Ahmed, and Bradley E. Britigan: Intraphagosomal Mycobacterium tuberculosis Acquires Iron from Both Extracellular Transferrin and Intracellular Iron Pools. IMPACT OF INTERFERON- $gamma$ AND HEMOCHROMATOSIS
J. Biol. Chem. 2002 277: 49727-49734. First Published on October 23, 2002; 10.1074/jbc.M209768200 [Abstract] [Full Text] [PDF]

Young-Hoon Han, Chang Y. Chung, Deborah Wessels, Stephen Stephens, Margaret A. Titus, David R. Soll, and Richard A. Firtel: Requirement of a Vasodilator-stimulated Phosphoprotein Family Member for Cell Adhesion, the Formation of Filopodia, and Chemotaxis in Dictyostelium
J. Biol. Chem. 2002 277: 49877-49887. First Published on October 17, 2002; 10.1074/jbc.M209107200 [Abstract] [Full Text] [PDF] Supplemental Data

Jhang Ho Pak, Yefim Manevich, Han Suk Kim, Sheldon I. Feinstein, and Aron B. Fisher: An Antisense Oligonucleotide to 1-cys Peroxiredoxin Causes Lipid Peroxidation and Apoptosis in Lung Epithelial Cells
J. Biol. Chem. 2002 277: 49927-49934. First Published on October 7, 2002; 10.1074/jbc.M204222200 [Abstract] [Full Text] [PDF]

Antonio Arroyo, Martin Modrianský, F. Behice Serinkan, Rosario I. Bello, Tatsuya Matsura, Jianfei Jiang, Vladimir A. Tyurin, Yulia Y. Tyurina, Bengt Fadeel, and Valerian E. Kagan: NADPH Oxidase-dependent Oxidation and Externalization of Phosphatidylserine during Apoptosis in Me₂SO-differentiated HL-60 Cells. ROLE IN PHAGOCYTIC CLEARANCE
J. Biol. Chem. 2002 277: 49965-49975. First Published on October 9, 2002; 10.1074/jbc.M204513200 [Abstract] [Full Text] [PDF]

Gang Xu, Carlos Arregui, Jack Lilien, and Janne Balsamo: PTP1B Modulates the Association of $beta$ -Catenin with N-cadherin through Binding to an Adjacent and Partially Overlapping Target Site
J. Biol. Chem. 2002 277: 49989-49997. First Published on October 10, 2002; 10.1074/jbc.M206454200 [Abstract] [Full Text] [PDF]

Esther Lechner, Daoxin Xie, Sandrine Grava, Emmanuelle Pigaglio, Severine Planchais, James A. H. Murray, Yves Parmentier, Jerome Mutterer, Bertrand Dubreucq, Wen-Hui Shen, and Pascal Genschik: The AtRbx1 Protein Is Part of Plant SCF Complexes, and Its Down-regulation Causes Severe Growth and Developmental Defects
J. Biol. Chem. 2002 277: 50069-50080. First Published on October 14, 2002; 10.1074/jbc.M204254200 [Abstract] [Full Text] [PDF]

Ming Shen, Eri Yoshida, Weiqun Yan, Takeshi Kawamoto, Ketut Suardita, Yasuhiko Koyano, Katsumi Fujimoto, Mitsuhide Noshiro, and Yukio Kato: Basic Helix-loop-helix Protein DEC1 Promotes Chondrocyte Differentiation at the Early and Terminal Stages
J. Biol. Chem. 2002 277: 50112-50120. First Published on October 15, 2002; 10.1074/jbc.M206771200 [Abstract] [Full Text] [PDF]

Nobumasa Takasugi, Yasuko Takahashi, Yuichi Morohashi, Taisuke Tomita, and Takeshi Iwatsubo: The Mechanism of $gamma$ -Secretase Activities through High Molecular Weight Complex Formation of Presenilins Is Conserved in Drosophila melanogaster and Mammals
J. Biol. Chem. 2002 277: 50198-50205. First Published on October 17, 2002; 10.1074/jbc.M205352200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Chaoxian Geng, Hung-Tat Leung, David R. Skingsley, Mladen I. Iovchev, Zhan Yin, Eugene P. Semenov, Martin G. Burg, Roger C. Hardie, and William L. Pak: Target of Drosophila photoreceptor synaptic transmission is a histamine-gated chloride channel encoded by ort (hclA).
J. Biol. Chem. 2002 277: 50214. [Full Text] [PDF]