Minireviews:

John M. Dietschy and Stephen D. Turley

Control of Cholesterol Turnover in the Mouse
J. Biol. Chem. 2002 277: 3801-3804. First Published on December 3, 2001; 10.1074/jbc.R100057200 [Full Text] [PDF]  

Accelerated Publications:

Mica Ohara-Imaizumi, Yoko Nakamichi, Toshiaki Tanaka, Hitoshi Ishida, and Shinya Nagamatsu

Imaging Exocytosis of Single Insulin Secretory Granules with Evanescent Wave Microscopy. DISTINCT BEHAVIOR OF GRANULE MOTION IN BIPHASIC INSULIN RELEASE
J. Biol. Chem. 2002 277: 3805-3808. First Published on December 21, 2001; 10.1074/jbc.C100712200 [Abstract] [Full Text] [PDF] Supplemental Data  

Bryce A. Nelson, Katherine A. Robinson, and Maria G. Buse

Insulin Acutely Regulates Munc18-c Subcellular Trafficking. ALTERED RESPONSE IN INSULIN-RESISTANT 3T3-L1 ADIPOCYTES
J. Biol. Chem. 2002 277: 3809-3812. First Published on December 18, 2001; 10.1074/jbc.C100645200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Vladimir N. Podust, Long-Sheng Chang, Robert Ott, Grigory L. Dianov, and Ellen Fanning

Reconstitution of Human DNA Polymerase Using Recombinant Baculoviruses. THE p12 SUBUNIT POTENTIATES DNA POLYMERIZING ACTIVITY OF THE FOUR-SUBUNIT ENZYME
J. Biol. Chem. 2002 277: 3894-3901. First Published on November 15, 2001; 10.1074/jbc.M109684200 [Abstract] [Full Text] [PDF]  

Abigail J. Bath, Susan E. Milsom, Niall A. Gormley, and Stephen E. Halford

Many Type IIs Restriction Endonucleases Interact with Two Recognition Sites before Cleaving DNA
J. Biol. Chem. 2002 277: 4024-4033. First Published on November 29, 2001; 10.1074/jbc.M108441200 [Abstract] [Full Text] [PDF]  

Niall A. Gormley, Anna L. Hillberg, and Stephen E. Halford

The Type IIs Restriction Endonuclease BspMI Is a Tetramer That Acts Concertedly at Two Copies of an Asymmetric DNA Sequence
J. Biol. Chem. 2002 277: 4034-4041. First Published on November 29, 2001; 10.1074/jbc.M108442200 [Abstract] [Full Text] [PDF]  

Maria Meijer, Feridoun Karimi-Busheri, Timothy Y. Huang, Michael Weinfeld, and Dallan Young

Pnk1, a DNA Kinase/Phosphatase Required for Normal Response to DNA Damage by -Radiation or Camptothecin in Schizosaccharomyces pombe
J. Biol. Chem. 2002 277: 4050-4055. First Published on November 29, 2001; 10.1074/jbc.M109383200 [Abstract] [Full Text] [PDF]  

Paul Nghiem, Peter K. Park, Yong-son Kim, Bimal N. Desai, and Stuart L. Schreiber

ATR Is Not Required for p53 Activation but Synergizes with p53 in the Replication Checkpoint
J. Biol. Chem. 2002 277: 4428-4434. First Published on November 15, 2001; 10.1074/jbc.M106113200 [Abstract] [Full Text] [PDF]  

Zhijie Wang, Eli Lazarov, Mike O'Donnell, and Myron F. Goodman

Resolving a Fidelity Paradox. WHY ESCHERICHIA COLI DNA POLYMERASE II MAKES MORE BASE SUBSTITUTION ERRORS IN AT- COMPARED WITH GC-RICH DNA
J. Biol. Chem. 2002 277: 4446-4454. First Published on December 3, 2001; 10.1074/jbc.M110006200 [Abstract] [Full Text] [PDF]  

Amrita Machwe, Liren Xiao, Shaji Theodore, and David K. Orren

DNase I Footprinting and Enhanced Exonuclease Function of the Bipartite Werner Syndrome Protein (WRN) Bound to Partially Melted Duplex DNA
J. Biol. Chem. 2002 277: 4492-4504. First Published on November 20, 2001; 10.1074/jbc.M108880200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Kyung-Ran You, Jing Wen, Soo-Taek Lee, and Dae-Ghon Kim

Cytochrome c Oxidase Subunit III. A MOLECULAR MARKER FOR N-(4-HYDROXYPHENYL)RETINAMIDE-INDUCED OXIDATIVE STRESS IN HEPATOMA CELLS
J. Biol. Chem. 2002 277: 3870-3877. First Published on November 6, 2001; 10.1074/jbc.M109284200 [Abstract] [Full Text] [PDF]  

Lance R. Johnson, Teresa K. Johnson, Michelle Desler, Troy A. Luster, Tamara Nowling, Robert E. Lewis, and Angie Rizzino

Effects of B-Myb on Gene Transcription. PHOSPHORYLATION-DEPENDENT ACTIVITY AND ACETYLATION BY p300
J. Biol. Chem. 2002 277: 4088-4097. First Published on December 3, 2001; 10.1074/jbc.M105112200 [Abstract] [Full Text] [PDF]  

Tadepalli Adilakshmi and Roney O. Laine

Ribosomal Protein S25 mRNA Partners with MTF-1 and La to Provide a p53-mediated Mechanism for Survival or Death
J. Biol. Chem. 2002 277: 4147-4151. First Published on December 7, 2001; 10.1074/jbc.M109785200 [Abstract] [Full Text] [PDF]  

R. Graham Hope, Denis J. Murphy, and John McLauchlan

The Domains Required to Direct Core Proteins of Hepatitis C Virus and GB Virus-B to Lipid Droplets Share Common Features with Plant Oleosin Proteins
J. Biol. Chem. 2002 277: 4261-4270. First Published on November 12, 2001; 10.1074/jbc.M108798200 [Abstract] [Full Text] [PDF]  

Dominik Haudenschild, Timothy Moseley, Larry Rose, and A. Hari Reddi

Soluble and Transmembrane Isoforms of Novel Interleukin-17 Receptor-like Protein by RNA Splicing and Expression in Prostate Cancer
J. Biol. Chem. 2002 277: 4309-4316. First Published on November 12, 2001; 10.1074/jbc.M109372200 [Abstract] [Full Text] [PDF]  

Johannes Uhl, Niko Klan, Matthias Rose, Karl-Dieter Entian, Oliver Werz, and Dieter Steinhilber

The 5-Lipoxygenase Promoter Is Regulated by DNA Methylation
J. Biol. Chem. 2002 277: 4374-4379. First Published on November 12, 2001; 10.1074/jbc.M107665200 [Abstract] [Full Text] [PDF]  

Anil Mishra, Simon P. Hogan, Eric B. Brandt, Norbert Wagner, Michael W. Crossman, Paul S. Foster, and Marc E. Rothenberg

Enterocyte Expression of the Eotaxin and Interleukin-5 Transgenes Induces Compartmentalized Dysregulation of Eosinophil Trafficking
J. Biol. Chem. 2002 277: 4406-4412. First Published on November 30, 2001; 10.1074/jbc.M110424200 [Abstract] [Full Text] [PDF]  

Johannes Fürst, Markus Ritter, Jakob Rudzki, Johann Danzl, Martin Gschwentner, Elke Scandella, Martin Jakab, Matthias König, Bernhard Oehl, Florian Lang, Peter Deetjen, and Markus Paulmichl

ICln Ion Channel Splice Variants in Caenorhabditis elegans. VOLTAGE DEPENDENCE AND INTERACTION WITH AN OPERON PARTNER PROTEIN
J. Biol. Chem. 2002 277: 4435-4445. First Published on November 12, 2001; 10.1074/jbc.M107372200 [Abstract] [Full Text] [PDF]  

Sarah Ross, Anri Tienhaara, Ming-Sum Lee, Li-Huei Tsai, and Grace Gill

GC Box-binding Transcription Factors Control the Neuronal Specific Transcription of the Cyclin-dependent Kinase 5 Regulator p35
J. Biol. Chem. 2002 277: 4455-4464. First Published on November 27, 2001; 10.1074/jbc.M110771200 [Abstract] [Full Text] [PDF]  

Cong Liu, Stephan W. Glasser, Huajing Wan, and Jeffrey A. Whitsett

GATA-6 and Thyroid Transcription Factor-1 Directly Interact and Regulate Surfactant Protein-C Gene Expression
J. Biol. Chem. 2002 277: 4519-4525. First Published on December 3, 2001; 10.1074/jbc.M107585200 [Abstract] [Full Text] [PDF]  

Kezhong Zhang, Sumiko Kurachi, and Kotoku Kurachi

Genetic Mechanisms of Age Regulation of Protein C and Blood Coagulation
J. Biol. Chem. 2002 277: 4532-4540. First Published on November 21, 2001; 10.1074/jbc.M109524200 [Abstract] [Full Text] [PDF] Supplemental Data  

RNA: Structure Metabolism and Catalysis:

Yue Jiang, Shani Blanga, Michal Amitsur, Roberto Meidler, Eli Krivosheyev, Mallikarjun Sundaram, Ashok C. Bajji, Darrell R. Davis, and Gabriel Kaufmann

Structural Features of tRNA^Lys Favored by Anticodon Nuclease as Inferred from Reactivities of Anticodon Stem and Loop Substrate Analogs
J. Biol. Chem. 2002 277: 3836-3841. First Published on November 26, 2001; 10.1074/jbc.M110072200 [Abstract] [Full Text] [PDF]  

Andrei S. Zolotukhin, Wei Tan, Jenifer Bear, Sergey Smulevitch, and Barbara K. Felber

U2AF Participates in the Binding of TAP (NXF1) to mRNA
J. Biol. Chem. 2002 277: 3935-3942. First Published on November 27, 2001; 10.1074/jbc.M107598200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Toshio Uchiumi, Sachiko Honma, Takaomi Nomura, Eric R. Dabbs, and Akira Hachimori

Translation Elongation by a Hybrid Ribosome in Which Proteins at the GTPase Center of the Escherichia coli Ribosome Are Replaced with Rat Counterparts
J. Biol. Chem. 2002 277: 3857-3862. First Published on November 29, 2001; 10.1074/jbc.M107730200 [Abstract] [Full Text] [PDF]  

Paul A. Price, Gethin R. Thomas, Aaron W. Pardini, William F. Figueira, Jeffrey M. Caputo, and Matthew K. Williamson

Discovery of a High Molecular Weight Complex of Calcium, Phosphate, Fetuin, and Matrix -Carboxyglutamic Acid Protein in the Serum of Etidronate-treated Rats
J. Biol. Chem. 2002 277: 3926-3934. First Published on November 27, 2001; 10.1074/jbc.M106366200 [Abstract] [Full Text] [PDF]  

Z. Elizabeth Floyd and Jacqueline M. Stephens

Interferon--mediated Activation and Ubiquitin-Proteasome-dependent Degradation of PPAR in Adipocytes
J. Biol. Chem. 2002 277: 4062-4068. First Published on November 30, 2001; 10.1074/jbc.M108473200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Qiang Liu, ZhenQin Xia, and Casey C. Case

Validated Zinc Finger Protein Designs for All 16 GNN DNA Triplet Targets
J. Biol. Chem. 2002 277: 3850-3856. First Published on November 28, 2001; 10.1074/jbc.M110669200 [Abstract] [Full Text] [PDF]  

Jarkko Valjakka, Kristiina Takkinenz, Tuija Teerinen, Hans Söderlund, and Juha Rouvinen

Structural Insights into Steroid Hormone Binding. THE CRYSTAL STRUCTURE OF A RECOMBINANT ANTI-TESTOSTERONE Fab FRAGMENT IN FREE AND TESTOSTERONE-BOUND FORMS
J. Biol. Chem. 2002 277: 4183-4190. First Published on November 13, 2001; 10.1074/jbc.M105579200 [Abstract] [Full Text] [PDF]  

Heinrich Delbrück, Günter Ziegelin, Erich Lanka, and Udo Heinemann

An Src Homology 3-like Domain Is Responsible for Dimerization of the Repressor Protein KorB Encoded by the Promiscuous IncP Plasmid RP4
J. Biol. Chem. 2002 277: 4191-4198. First Published on November 15, 2001; 10.1074/jbc.M110103200 [Abstract] [Full Text] [PDF]  

Andrew G. Purkiss, Orval A. Bateman, Julia M. Goodfellow, Nicolette H. Lubsen, and Christine Slingsby

The X-ray Crystal Structure of Human S-crystallin C-terminal Domain
J. Biol. Chem. 2002 277: 4199-4205. First Published on November 8, 2001; 10.1074/jbc.M110083200 [Abstract] [Full Text] [PDF]  

Ling Fu and Jack J-N Liang

Detection of Protein-Protein Interactions among Lens Crystallins in a Mammalian Two-hybrid System Assay
J. Biol. Chem. 2002 277: 4255-4260. First Published on November 7, 2001; 10.1074/jbc.M110027200 [Abstract] [Full Text] [PDF]  

Ralph Wissmann, Wolfgang Bildl, Heinz Neumann, Andre F. Rivard, Nikolaj Klöcker, Dietmar Weitz, Uwe Schulte, John P. Adelman, Detlef Bentrop, and Bernd Fakler

A Helical Region in the C Terminus of Small-conductance Ca²⁺-activated K⁺ Channels Controls Assembly with Apo-calmodulin
J. Biol. Chem. 2002 277: 4558-4564. First Published on November 26, 2001; 10.1074/jbc.M109240200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Michael H. Woo, John R. Vance, Ana R. Otero Marcos, Christian Bailly, and Mary-Ann Bjornsti

Active Site Mutations in DNA Topoisomerase I Distinguish the Cytotoxic Activities of Camptothecin and the Indolocarbazole, Rebeccamycin
J. Biol. Chem. 2002 277: 3813-3822. First Published on December 3, 2001; 10.1074/jbc.M110484200 [Abstract] [Full Text] [PDF]  

Chittoor P. Swaminathan, Umesh T. Sankpal, Desirazu N. Rao, and Avadhesha Surolia

Water-assisted Dual Mode Cofactor Recognition by HhaI DNA Methyltransferase
J. Biol. Chem. 2002 277: 4042-4049. First Published on November 29, 2001; 10.1074/jbc.M109237200 [Abstract] [Full Text] [PDF]  

Yongting Wang, Dapeng Sun, and Victor L. Davidson

Use of Indirect Site-directed Mutagenesis to Alter the Substrate Specificity of Methylamine Dehydrogenase
J. Biol. Chem. 2002 277: 4119-4122. First Published on December 3, 2001; 10.1074/jbc.M109270200 [Abstract] [Full Text] [PDF]  

Liliana M. Sampaleanu, Bomina Yu, and P. Lynne Howell

Mutational Analysis of Duck 2 Crystallin and the Structure of an Inactive Mutant with Bound Substrate Provide Insight into the Enzymatic Mechanism of Argininosuccinate Lyase
J. Biol. Chem. 2002 277: 4166-4175. First Published on November 6, 2001; 10.1074/jbc.M107465200 [Abstract] [Full Text] [PDF]  

Sharda P. Singh, Andrzej J. Janecki, Sanjay K. Srivastava, Sanjay Awasthi, Yogesh C. Awasthi, Shujuan J. Xia, and Piotr Zimniak

Membrane Association of Glutathione S-Transferase mGSTA4-4, an Enzyme That Metabolizes Lipid Peroxidation Products
J. Biol. Chem. 2002 277: 4232-4239. First Published on November 19, 2001; 10.1074/jbc.M109678200 [Abstract] [Full Text] [PDF]  

Bo-Yeon Kwak, Yong-Mei Zhang, Mikyung Yun, Richard J. Heath, Charles O. Rock, Suzanne Jackowski, and Hee-Won Park

Structure and Mechanism of CTP:Phosphocholine Cytidylyltransferase (LicC) from Streptococcus pneumoniae
J. Biol. Chem. 2002 277: 4343-4350. First Published on November 12, 2001; 10.1074/jbc.M109163200 [Abstract] [Full Text] [PDF]  

Bryant W. Miles, James B. Thoden, Hazel M. Holden, and Frank M. Raushel

Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin
J. Biol. Chem. 2002 277: 4368-4373. First Published on November 29, 2001; 10.1074/jbc.M108582200 [Abstract] [Full Text] [PDF]  

Emily I. Chen, Steven J. Kridel, Eric W. Howard, Weizhong Li, Adam Godzik, and Jeffrey W. Smith

A Unique Substrate Recognition Profile for Matrix Metalloproteinase-2
J. Biol. Chem. 2002 277: 4485-4491. First Published on November 2, 2001; 10.1074/jbc.M109469200 [Abstract] [Full Text] [PDF]  

Soo-A Kim, Gregory S. Taylor, Knut M. Torgersen, and Jack E. Dixon

Myotubularin and MTMR2, Phosphatidylinositol 3-Phosphatases Mutated in Myotubular Myopathy and Type 4B Charcot-Marie-Tooth Disease
J. Biol. Chem. 2002 277: 4526-4531. First Published on December 3, 2001; 10.1074/jbc.M111087200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Brian D. Fink, Young-Sun Hong, Mary M. Mathahs, Thomas D. Scholz, Joseph S. Dillon, and William I. Sivitz

UCP2-dependent Proton Leak in Isolated Mammalian Mitochondria
J. Biol. Chem. 2002 277: 3918-3925. First Published on November 26, 2001; 10.1074/jbc.M107955200 [Abstract] [Full Text] [PDF]  

Sanja Roje, Sherwin Y. Chan, Fatma Kaplan, Rhonda K. Raymond, Donald W. Horne, Dean R. Appling, and Andrew D. Hanson

Metabolic Engineering in Yeast Demonstrates That S-Adenosylmethionine Controls Flux through the Methylenetetrahydrofolate Reductase Reaction in Vivo
J. Biol. Chem. 2002 277: 4056-4061. First Published on November 29, 2001; 10.1074/jbc.M110651200 [Abstract] [Full Text] [PDF]  

Fiona M. Campbell, Ray Kozak, Alese Wagner, Judith Y. Altarejos, Jason R. B. Dyck, Darrell D. Belke, David L. Severson, Daniel P. Kelly, and Gary D. Lopaschuk

A Role for Peroxisome Proliferator-activated Receptor (PPAR) in the Control of Cardiac Malonyl-CoA Levels. REDUCED FATTY ACID OXIDATION RATES AND INCREASED GLUCOSE OXIDATION RATES IN THE HEARTS OF MICE LACKING PPAR ARE ASSOCIATED WITH HIGHER CONCENTRATIONS OF MALONYL-CoA AND REDUCED EXPRESSION OF MALONYL-CoA DECARBOXYLASE
J. Biol. Chem. 2002 277: 4098-4103. First Published on December 4, 2001; 10.1074/jbc.M106054200 [Abstract] [Full Text] [PDF]  

Antonella Spinazzola, Ramon Marti, Ichizo Nishino, Antonio L. Andreu, Ali Naini, Saba Tadesse, Ivana Pela, Enrico Zammarchi, M. Alice Donati, Juan A. Oliver, and Michio Hirano

Altered Thymidine Metabolism Due to Defects of Thymidine Phosphorylase
J. Biol. Chem. 2002 277: 4128-4133. First Published on December 3, 2001; 10.1074/jbc.M111028200 [Abstract] [Full Text] [PDF]  

Arantxa Tabernero, Ana Velasco, Begoña Granda, Eva M. Lavado, and José M. Medina

Transcytosis of Albumin in Astrocytes Activates the Sterol Regulatory Element-binding Protein-1, Which Promotes the Synthesis of the Neurotrophic Factor Oleic Acid
J. Biol. Chem. 2002 277: 4240-4246. First Published on November 27, 2001; 10.1074/jbc.M108760200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Betty Reinboth, Eric Hanssen, Edward G. Cleary, and Mark A. Gibson

Molecular Interactions of Biglycan and Decorin with Elastic Fiber Components. BIGLYCAN FORMS A TERNARY COMPLEX WITH TROPOELASTIN AND MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 1
J. Biol. Chem. 2002 277: 3950-3957. First Published on November 26, 2001; 10.1074/jbc.M109540200 [Abstract] [Full Text] [PDF]  

Kenji Uchimura, Fathy M. El-Fasakhany, Mayuko Hori, Stefan Hemmerich, Sarah E. Blink, Geoffrey S. Kansas, Akiko Kanamori, Kensuke Kumamoto, Reiji Kannagi, and Takashi Muramatsu

Specificities of N-Acetylglucosamine-6-O-sulfotransferases in Relation to L-selectin Ligand Synthesis and Tumor-associated Enzyme Expression
J. Biol. Chem. 2002 277: 3979-3984. First Published on November 28, 2001; 10.1074/jbc.M106587200 [Abstract] [Full Text] [PDF]  

Wayne A. Cabral, Andrzej Fertala, Laura K. Green, Jarmo Körkkö, Antonella Forlino, and Joan C. Marini

Procollagen with Skipping of 1(I) Exon 41 Has Lower Binding Affinity for 1(I) C-telopeptide, Impaired in Vitro Fibrillogenesis, and Altered Fibril Morphology
J. Biol. Chem. 2002 277: 4215-4222. First Published on November 8, 2001; 10.1074/jbc.M109048200 [Abstract] [Full Text] [PDF]  

Gloria A. Di Lullo, Shawn M. Sweeney, Jarmo Körkkö, Leena Ala-Kokko, and James D. San Antonio

Mapping the Ligand-binding Sites and Disease-associated Mutations on the Most Abundant Protein in the Human, Type I Collagen
J. Biol. Chem. 2002 277: 4223-4231. First Published on November 9, 2001; 10.1074/jbc.M110709200 [Abstract] [Full Text] [PDF]  

Zenzo Isogai, Anders Aspberg, Douglas R. Keene, Robert N. Ono, Dieter P. Reinhardt, and Lynn Y. Sakai

Versican Interacts with Fibrillin-1 and Links Extracellular Microfibrils to Other Connective Tissue Networks
J. Biol. Chem. 2002 277: 4565-4572. First Published on November 28, 2001; 10.1074/jbc.M110583200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Arun K. Thukkani, Fong-Fu Hsu, Jan R. Crowley, Robert B. Wysolmerski, Carolyn J. Albert, and David A. Ford

Reactive Chlorinating Species Produced during Neutrophil Activation Target Tissue Plasmalogens. PRODUCTION OF THE CHEMOATTRACTANT, 2-CHLOROHEXADECANAL
J. Biol. Chem. 2002 277: 3842-3849. First Published on November 27, 2001; 10.1074/jbc.M109489200 [Abstract] [Full Text] [PDF]  

Tilla S. Worgall, Rebecca A. Johnson, Toru Seo, Hedi Gierens, and Richard J. Deckelbaum

Unsaturated Fatty Acid-mediated Decreases in Sterol Regulatory Element-mediated Gene Transcription Are Linked to Cellular Sphingolipid Metabolism
J. Biol. Chem. 2002 277: 3878-3885. First Published on November 13, 2001; 10.1074/jbc.M102393200 [Abstract] [Full Text] [PDF]  

R. Jason Kirby, Shuqin Zheng, Patrick Tso, Philip N. Howles, and David Y. Hui

Bile Salt-stimulated Carboxyl Ester Lipase Influences Lipoprotein Assembly and Secretion in Intestine. A PROCESS MEDIATED VIA CERAMIDE HYDROLYSIS
J. Biol. Chem. 2002 277: 4104-4109. First Published on December 3, 2001; 10.1074/jbc.M107549200 [Abstract] [Full Text] [PDF]  

Debi K. Swertfeger, Guojun Bu, and David Y. Hui

Low Density Lipoprotein Receptor-related Protein Mediates Apolipoprotein E Inhibition of Smooth Muscle Cell Migration
J. Biol. Chem. 2002 277: 4141-4146. First Published on December 5, 2001; 10.1074/jbc.M109124200 [Abstract] [Full Text] [PDF]  

Sara Deakin, Ilia Leviev, Monica Gomaraschi, Laura Calabresi, Guido Franceschini, and Richard W. James

Enzymatically Active Paraoxonase-1 Is Located at the External Membrane of Producing Cells and Released by a High Affinity, Saturable, Desorption Mechanism
J. Biol. Chem. 2002 277: 4301-4308. First Published on November 28, 2001; 10.1074/jbc.M107440200 [Abstract] [Full Text] [PDF]  

Yan Shen, Aivar Lookene, Solveig Nilsson, and Gunilla Olivecrona

Functional Analyses of Human Apolipoprotein CII by Site-directed Mutagenesis. IDENTIFICATION OF RESIDUES IMPORTANT FOR ACTIVATION OF LIPOPROTEIN LIPASE
J. Biol. Chem. 2002 277: 4334-4342. First Published on November 21, 2001; 10.1074/jbc.M105421200 [Abstract] [Full Text] [PDF]  

Meihui Pan, Jun-shan Liang, Edward A. Fisher, and Henry N. Ginsberg

The Late Addition of Core Lipids to Nascent Apolipoprotein B100, Resulting in the Assembly and Secretion of Triglyceride-rich Lipoproteins, Is Independent of Both Microsomal Triglyceride Transfer Protein Activity and New Triglyceride Synthesis
J. Biol. Chem. 2002 277: 4413-4421. First Published on November 9, 2001; 10.1074/jbc.M107460200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Judith Racapé, Alain Lecoq, Régine Romi-Lebrun, Jessica Liu, Martin Kohler, Maria L. Garcia, André Ménez, and Sylvaine Gasparini

Characterization of a Novel Radiolabeled Peptide Selective for a Subpopulation of Voltage-gated Potassium Channels in Mammalian Brain
J. Biol. Chem. 2002 277: 3886-3893. First Published on November 13, 2001; 10.1074/jbc.M109886200 [Abstract] [Full Text] [PDF]  

Barry J. Bowman and Emma Jean Bowman

Mutations in Subunit c of the Vacuolar ATPase Confer Resistance to Bafilomycin and Identify a Conserved Antibiotic Binding Site
J. Biol. Chem. 2002 277: 3965-3972. First Published on November 27, 2001; 10.1074/jbc.M109756200 [Abstract] [Full Text] [PDF]  

Lihi Brocke, Annie Bendahan, Myriam Grunewald, and Baruch I. Kanner

Proximity of Two Oppositely Oriented Reentrant Loops in the Glutamate Transporter GLT-1 Identified by Paired Cysteine Mutagenesis
J. Biol. Chem. 2002 277: 3985-3992. First Published on November 27, 2001; 10.1074/jbc.M107735200 [Abstract] [Full Text] [PDF]  

Biljana Jovov, Bakhrom K. Berdiev, Catherine M. Fuller, Hong-Long Ji, and Dale J. Benos

The Serine Protease Trypsin Cleaves C Termini of - and -Subunits of Epithelial Na⁺ Channels
J. Biol. Chem. 2002 277: 4134-4140. First Published on December 5, 2001; 10.1074/jbc.M108354200 [Abstract] [Full Text] [PDF]  

Hyacinth Sterling, Dao-Hong Lin, Rui-Min Gu, Ke Dong, Steven C. Hebert, and Wen-Hui Wang

Inhibition of Protein-tyrosine Phosphatase Stimulates the Dynamin-dependent Endocytosis of ROMK1
J. Biol. Chem. 2002 277: 4317-4323. First Published on November 21, 2001; 10.1074/jbc.M109739200 [Abstract] [Full Text] [PDF]  

Jaekwon Lee, Maria Marjorette O. Peña, Yasuhiro Nose, and Dennis J. Thiele

Biochemical Characterization of the Human Copper Transporter Ctr1
J. Biol. Chem. 2002 277: 4380-4387. First Published on December 4, 2001; 10.1074/jbc.M104728200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Andrew Freywald, Nigel Sharfe, and Chaim M. Roifman

The Kinase-null EphB6 Receptor Undergoes Transphosphorylation in a Complex with EphB1
J. Biol. Chem. 2002 277: 3823-3828. First Published on November 16, 2001; 10.1074/jbc.M108011200 [Abstract] [Full Text] [PDF]  

Takumi Kawaguchi, Kiyoshi Osatomi, Hiromi Yamashita, Tsutomu Kabashima, and Kosaku Uyeda

Mechanism for Fatty Acid "Sparing" Effect on Glucose-induced Transcription. REGULATION OF CARBOHYDRATE-RESPONSIVE ELEMENT-BINDING PROTEIN BY AMP-ACTIVATED PROTEIN KINASE
J. Biol. Chem. 2002 277: 3829-3835. First Published on November 27, 2001; 10.1074/jbc.M107895200 [Abstract] [Full Text] [PDF]  

Nywana Sizemore, Natalia Lerner, Nicole Dombrowski, Hiroaki Sakurai, and George R. Stark

Distinct Roles of the IB Kinase and Subunits in Liberating Nuclear Factor B (NF-B) from IB and in Phosphorylating the p65 Subunit of NF-B
J. Biol. Chem. 2002 277: 3863-3869. First Published on December 3, 2001; 10.1074/jbc.M110572200 [Abstract] [Full Text] [PDF]  

Philippe Delerive, Yifei Wu, Thomas P. Burris, William W. Chin, and Chen S. Suen

PGC-1 Functions as a Transcriptional Coactivator for the Retinoid X Receptors
J. Biol. Chem. 2002 277: 3913-3917. First Published on November 19, 2001; 10.1074/jbc.M109409200 [Abstract] [Full Text] [PDF]  

Anirban Datta, Francois Huber, and David Boettiger

Phosphorylation of ₃ Integrin Controls Ligand Binding Strength
J. Biol. Chem. 2002 277: 3943-3949. First Published on November 26, 2001; 10.1074/jbc.M109536200 [Abstract] [Full Text] [PDF]  

Shinya Nishi, Koji Nakabayashi, Brian Kobilka, and Aaron J. W. Hsueh

The Ectodomain of the Luteinizing Hormone Receptor Interacts with Exoloop 2 to Constrain the Transmembrane Region. STUDIES USING CHIMERIC HUMAN AND FLY RECEPTORS
J. Biol. Chem. 2002 277: 3958-3964. First Published on November 26, 2001; 10.1074/jbc.M109617200 [Abstract] [Full Text] [PDF]  

Xiao Yi Yang, Li Hua Wang, Kelly Mihalic, Weihua Xiao, Taosheng Chen, Peng Li, Larry M. Wahl, and William L. Farrar

Interleukin (IL)-4 Indirectly Suppresses IL-2 Production by Human T Lymphocytes via Peroxisome Proliferator-activated Receptor Activated by Macrophage-derived 12/15-Lipoxygenase Ligands
J. Biol. Chem. 2002 277: 3973-3978. First Published on November 28, 2001; 10.1074/jbc.M105619200 [Abstract] [Full Text] [PDF]  

Emma Teixeiro, Patricia Fuentes, Begoña Galocha, Balbino Alarcón, and Rafael Bragado

T Cell Receptor-mediated Signal Transduction Controlled by the Chain Transmembrane Domain. APOPTOSIS-DEFICIENT CELLS DISPLAY UNBALANCED MITOGEN-ACTIVATED PROTEIN KINASES ACTIVITIES UPON T CELL RECEPTOR ENGAGEMENT
J. Biol. Chem. 2002 277: 3993-4002. First Published on November 27, 2001; 10.1074/jbc.M107797200 [Abstract] [Full Text] [PDF]  

Huiyan Zeng, Dezheng Zhao, and Debabrata Mukhopadhyay

Flt-1-mediated Down-regulation of Endothelial Cell Proliferation through Pertussis Toxin-sensitive G Proteins, Subunits, Small GTPase CDC42, and Partly by Rac-1
J. Biol. Chem. 2002 277: 4003-4009. First Published on November 28, 2001; 10.1074/jbc.M110842200 [Abstract] [Full Text] [PDF]  

Madalina Stanciu and Donald B. DeFranco

Prolonged Nuclear Retention of Activated Extracellular Signal-regulated Protein Kinase Promotes Cell Death Generated by Oxidative Toxicity or Proteasome Inhibition in a Neuronal Cell Line
J. Biol. Chem. 2002 277: 4010-4017. First Published on November 28, 2001; 10.1074/jbc.M104479200 [Abstract] [Full Text] [PDF]  

Uma Kant Misra and Salvatore Vincent Pizzo

Regulation of Cytosolic Phospholipase A₂ Activity in Macrophages Stimulated with Receptor-recognized Forms of ₂-Macroglobulin. ROLE IN MITOGENESIS AND CELL PROLIFERATION
J. Biol. Chem. 2002 277: 4069-4078. First Published on November 30, 2001; 10.1074/jbc.M109764200 [Abstract] [Full Text] [PDF]  

Joanne T. Hulme, Misol Ahn, Stephen D. Hauschka, Todd Scheuer, and William A. Catterall

A Novel Leucine Zipper Targets AKAP15 and Cyclic AMP-dependent Protein Kinase to the C Terminus of the Skeletal Muscle Ca²⁺ Channel and Modulates Its Function
J. Biol. Chem. 2002 277: 4079-4087. First Published on November 30, 2001; 10.1074/jbc.M109814200 [Abstract] [Full Text] [PDF]  

Eve Zentrich, Sun-Young Han, Luis Pessoa-Brandao, Laura Butterfield, and Lynn E. Heasley

Collaboration of JNKs and ERKs in Nerve Growth Factor Regulation of the Neurofilament Light Chain Promoter in PC12 Cells
J. Biol. Chem. 2002 277: 4110-4118. First Published on December 3, 2001; 10.1074/jbc.M107824200 [Abstract] [Full Text] [PDF]  

Peter Speck, Masato Ikeda, Akiko Ikeda, Howard M. Lederman, and Richard Longnecker

Signal Transduction through the B Cell Antigen Receptor Is Normal in Ataxia-Telangiectasia B Lymphocytes
J. Biol. Chem. 2002 277: 4123-4127. First Published on December 3, 2001; 10.1074/jbc.M110109200 [Abstract] [Full Text] [PDF]  

Shuting Bai and Xu Cao

A Nuclear Antagonistic Mechanism of Inhibitory Smads in Transforming Growth Factor- Signaling
J. Biol. Chem. 2002 277: 4176-4182. First Published on November 15, 2001; 10.1074/jbc.M105105200 [Abstract] [Full Text] [PDF]  

Anireddy S. N. Reddy, Irene S. Day, S. B. Narasimhulu, Farida Safadi, Vaka S. Reddy, Maxim Golovkin, and Melissa J. Harnly

Isolation and Characterization of a Novel Calmodulin-binding Protein from Potato
J. Biol. Chem. 2002 277: 4206-4214. First Published on October 29, 2001; 10.1074/jbc.M104595200 [Abstract] [Full Text] [PDF]  

Ming L. Chen, Charalabos Pothoulakis, and J. Thomas LaMont

Protein Kinase C Signaling Regulates ZO-1 Translocation and Increased Paracellular Flux of T84 Colonocytes Exposed to Clostridium difficile Toxin A
J. Biol. Chem. 2002 277: 4247-4254. First Published on November 29, 2001; 10.1074/jbc.M109254200 [Abstract] [Full Text] [PDF]  

David Fulton, Jason Fontana, Grzegorz Sowa, Jean-Philippe Gratton, Michelle Lin, Kai-Xun Li, Belinda Michell, Bruce E. Kemp, David Rodman, and William C. Sessa

Localization of Endothelial Nitric-oxide Synthase Phosphorylated on Serine 1179 and Nitric Oxide in Golgi and Plasma Membrane Defines the Existence of Two Pools of Active Enzyme
J. Biol. Chem. 2002 277: 4277-4284. First Published on November 29, 2001; 10.1074/jbc.M106302200 [Abstract] [Full Text] [PDF]  

Michael J. Feldhaus, Andrew S. Weyrich, Guy A. Zimmerman, and Thomas M. McIntyre

Ceramide Generation in Situ Alters Leukocyte Cytoskeletal Organization and ₂-Integrin Function and Causes Complete Degranulation
J. Biol. Chem. 2002 277: 4285-4293. First Published on November 12, 2001; 10.1074/jbc.M106653200 [Abstract] [Full Text] [PDF]  

Olga Ilkaeva, Lisa N. Kinch, Ruth H. Paulssen, and Elliott M. Ross

Mutations in the Carboxyl-terminal Domain of Phospholipase C-1 Delineate the Dimer Interface and a Potential G_q Interaction Site
J. Biol. Chem. 2002 277: 4294-4300. First Published on November 29, 2001; 10.1074/jbc.M109612200 [Abstract] [Full Text] [PDF]  

Alexander H. Stegh, Bryan C. Barnhart, Jörg Volkland, Alicia Algeciras-Schimnich, Ning Ke, John C. Reed, and Marcus E. Peter

Inactivation of Caspase-8 on Mitochondria of Bcl-x_L-expressing MCF7-Fas Cells. ROLE FOR THE BIFUNCTIONAL APOPTOSIS REGULATOR PROTEIN
J. Biol. Chem. 2002 277: 4351-4360. First Published on December 3, 2001; 10.1074/jbc.M108947200 [Abstract] [Full Text] [PDF]  

Gareth Williams, Emma-Jane Williams, and Patrick Doherty

Dimeric Versions of Two Short N-cadherin Binding Motifs (HAVDI and INPISG) Function as N-cadherin Agonists
J. Biol. Chem. 2002 277: 4361-4367. First Published on November 28, 2001; 10.1074/jbc.M109185200 [Abstract] [Full Text] [PDF]  

Mengwei Zang, Cynthia Hayne, and Zhijun Luo

Interaction between Active Pak1 and Raf-1 Is Necessary for Phosphorylation and Activation of Raf-1
J. Biol. Chem. 2002 277: 4395-4405. First Published on November 30, 2001; 10.1074/jbc.M110000200 [Abstract] [Full Text] [PDF]  

Christopher T. Richards, Ozgur Ogut, and Frank V. Brozovich

Agonist-induced Force Enhancement. THE ROLE OF ISOFORMS AND PHOSPHORYLATION OF THE MYOSIN-TARGETING SUBUNIT OF MYOSIN LIGHT CHAIN PHOSPHATASE
J. Biol. Chem. 2002 277: 4422-4427. First Published on November 28, 2001; 10.1074/jbc.M111047200 [Abstract] [Full Text] [PDF]  

Anthony D. Cristillo and Barbara E. Bierer

Identification of Novel Targets of Immunosuppressive Agents by cDNA-based Microarray Analysis
J. Biol. Chem. 2002 277: 4465-4476. First Published on November 1, 2001; 10.1074/jbc.M108598200 [Abstract] [Full Text] [PDF]  

Mandy J. Ludford-Menting, Suzanne J. Thomas, Blessing Crimeen, Lisa J. Harris, Bruce E. Loveland, Margaret Bills, Sarah Ellis, and Sarah M. Russell

A Functional Interaction between CD46 and DLG4. A ROLE FOR DLG4 IN EPITHELIAL POLARIZATION
J. Biol. Chem. 2002 277: 4477-4484. First Published on November 19, 2001; 10.1074/jbc.M108479200 [Abstract] [Full Text] [PDF]  

HongBin Wang and Marcelo G. Kazanietz

Chimaerins, Novel Non-protein Kinase C Phorbol Ester Receptors, Associate with Tmp21-I (p23). EVIDENCE FOR A NOVEL ANCHORING MECHANISM INVOLVING THE CHIMAERIN C1 DOMAIN
J. Biol. Chem. 2002 277: 4541-4550. First Published on October 31, 2001; 10.1074/jbc.M107150200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Gowrishankar Banumathy, Varsha Singh, and Utpal Tatu

Host Chaperones Are Recruited in Membrane-bound Complexes by Plasmodium falciparum
J. Biol. Chem. 2002 277: 3902-3912. First Published on November 15, 2001; 10.1074/jbc.M110513200 [Abstract] [Full Text] [PDF]  

Helen R. Burgar, Helen D. Burns, Joanna L. Elsden, Maria D. Lalioti, and John K. Heath

Association of the Signaling Adaptor FRS2 with Fibroblast Growth Factor Receptor 1 (Fgfr1) Is Mediated by Alternative Splicing of the Juxtamembrane Domain
J. Biol. Chem. 2002 277: 4018-4023. First Published on November 29, 2001; 10.1074/jbc.M107785200 [Abstract] [Full Text] [PDF]  

Nguyen Tien Huy, Kaeko Kamei, Takushi Yamamoto, Yoshiro Kondo, Kenji Kanaori, Ryo Takano, Kunihiko Tajima, and Saburo Hara

Clotrimazole Binds to Heme and Enhances Heme-dependent Hemolysis. PROPOSED ANTIMALARIAL MECHANISM OF CLOTRIMAZOLE
J. Biol. Chem. 2002 277: 4152-4158. First Published on November 13, 2001; 10.1074/jbc.M107285200 [Abstract] [Full Text] [PDF]  

Yuanhe Li, Oliver Spangenberg, Ingo Paarmann, Manfred Konrad, and Arnon Lavie

Structural Basis for Nucleotide-dependent Regulation of Membrane-associated Guanylate Kinase-like Domains
J. Biol. Chem. 2002 277: 4159-4165. First Published on November 29, 2001; 10.1074/jbc.M110792200 [Abstract] [Full Text] [PDF]  

Sean P. Kessler, Janette B. Gomos, Thomas S. Scheidemantel, Theresa M. Rowe, Heather L. Smith, and Ganes C. Sen

The Germinal Isozyme of Angiotensin-converting Enzyme Can Substitute for the Somatic Isozyme in Maintaining Normal Renal Structure and Functions
J. Biol. Chem. 2002 277: 4271-4276. First Published on November 26, 2001; 10.1074/jbc.M109474200 [Abstract] [Full Text] [PDF]  

Shen Liang Chen, Kelly A. Loffler, Dagang Chen, Michael R. Stallcup, and George E. O. Muscat

The Coactivator-associated Arginine Methyltransferase Is Necessary for Muscle Differentiation. CARM1 COACTIVATES MYOCYTE ENHANCER FACTOR-2
J. Biol. Chem. 2002 277: 4324-4333. First Published on November 16, 2001; 10.1074/jbc.M109835200 [Abstract] [Full Text] [PDF]  

Amina F. Zebboudj, Minori Imura, and Kristina Boström

Matrix GLA Protein, a Regulatory Protein for Bone Morphogenetic Protein-2
J. Biol. Chem. 2002 277: 4388-4394. First Published on December 6, 2001; 10.1074/jbc.M109683200 [Abstract] [Full Text] [PDF]  

Silvio Zaina, Linda Pettersson, Bo Ahrén, Lena Brånén, A. Bassim Hassan, Marie Lindholm, Ragnar Mattsson, Johan Thyberg, and Jan Nilsson

Insulin-like Growth Factor II Plays a Central Role in Atherosclerosis in a Mouse Model
J. Biol. Chem. 2002 277: 4505-4511. First Published on November 28, 2001; 10.1074/jbc.M108061200 [Abstract] [Full Text] [PDF]  

Yong Zhan, Joseph V. Virbasius, Xi Song, Darcy P. Pomerleau, and G. Wayne Zhou

The p40^phox and p47^phox PX Domains of NADPH Oxidase Target Cell Membranes via Direct and Indirect Recruitment by Phosphoinositides
J. Biol. Chem. 2002 277: 4512-4518. First Published on November 29, 2001; 10.1074/jbc.M109520200 [Abstract] [Full Text] [PDF]  

Beat Kunz, Ruth Lierheimer, Christoph Rader, Marianne Spirig, Urs Ziegler, and Peter Sonderegger

Axonin-1/TAG-1 Mediates Cell-Cell Adhesion by a Cis-assisted Trans-interaction
J. Biol. Chem. 2002 277: 4551-4557. First Published on December 3, 2001; 10.1074/jbc.M109779200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Andrea Todisco, Nonthalee Pausawasdi, Saravanan Ramamoorthy, John Del Valle, Rebecca W. Van Dyke, and Frederick K. Askari

Functional role of protein kinase B/Akt in gastric acid secretion.
J. Biol. Chem. 2002 277: 4573. [Full Text] [PDF]  

Motoyoshi Nomizu, Grzegorz Pietrzynski, Tamaki Kato, Paule Lachance, Robert Menard, and Edmund Ziomek

Substrate specificity of the streptococcal cysteine protease.
J. Biol. Chem. 2002 277: 4574. [Full Text] [PDF]  

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