JBC -- Table of Contents (May 23 2003, 278, (21))

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Matthew C. Trudeau and William N. Zagotta: Calcium/Calmodulin Modulation of Olfactory and Rod Cyclic Nucleotide-gated Ion Channels
J. Biol. Chem. 2003 278: 18705-18708. First Published on March 7, 2003; doi:10.1074/jbc.R300001200 [Abstract] [Full Text] [PDF]

DNA: Replication Repair and Recombination:

Anne Stary, Patricia Kannouche, Alan R. Lehmann, and Alain Sarasin: Role of DNA Polymerase ${eta}$ in the UV Mutation Spectrum in Human Cells
J. Biol. Chem. 2003 278: 18767-18775. First Published on March 18, 2003; doi:10.1074/jbc.M211838200 [Abstract] [Full Text] [PDF]

Masanori Ogawa, Siripan Limsirichaikul, Atsuko Niimi, Shigenori Iwai, Shonen Yoshida, and Motoshi Suzuki: Distinct Function of Conserved Amino Acids in the Fingers of Saccharomyces cerevisiae DNA Polymerase ${alpha}$
J. Biol. Chem. 2003 278: 19071-19078. First Published on March 7, 2003; doi:10.1074/jbc.M208605200 [Abstract] [Full Text] [PDF]

Siripan Limsirichaikul, Masanori Ogawa, Atsuko Niimi, Shigenori Iwai, Takashi Murate, Shonen Yoshida, and Motoshi Suzuki: The Gly-952 Residue of Saccharomyces cerevisiae DNA Polymerase ${alpha}$ Is Important in Discriminating Correct Deoxyribonucleotides from Incorrect Ones
J. Biol. Chem. 2003 278: 19079-19086. First Published on March 7, 2003; doi:10.1074/jbc.M208604200 [Abstract] [Full Text] [PDF]

Eitan Glick, Janice S. Chau, Kellie L. Vigna, Scott D. McCulloch, Elinor T. Adman, Thomas A. Kunkel, and Lawrence A. Loeb: Amino Acid Substitutions at Conserved Tyrosine 52 Alter Fidelity and Bypass Efficiency of Human DNA Polymerase ${eta}$
J. Biol. Chem. 2003 278: 19341-19346. First Published on March 18, 2003; doi:10.1074/jbc.M300686200 [Abstract] [Full Text] [PDF]

Keehwan Kwon, Chunyang Cao, and James T. Stivers: A Novel Zinc Snap Motif Conveys Structural Stability to 3-Methyladenine DNA Glycosylase I
J. Biol. Chem. 2003 278: 19442-19446. First Published on March 24, 2003; doi:10.1074/jbc.M300934200 [Abstract] [Full Text] [PDF]

Marcel Hohl, Fabrizio Thorel, Stuart G. Clarkson, and Orlando D. Schärer: Structural Determinants for Substrate Binding and Catalysis by the Structure-specific Endonuclease XPG
J. Biol. Chem. 2003 278: 19500-19508. First Published on March 18, 2003; doi:10.1074/jbc.M213155200 [Abstract] [Full Text] [PDF]

Anne Jensen, Guillaume Calvayrac, Bensu Karahalil, Vilhelm A. Bohr, and Tinna Stevnsner: Mammalian 8-Oxoguanine DNA Glycosylase 1 Incises 8-Oxoadenine Opposite Cytosine in Nuclei and Mitochondria, while a Different Glycosylase Incises 8-Oxoadenine Opposite Guanine in Nuclei
J. Biol. Chem. 2003 278: 19541-19548. First Published on March 18, 2003; doi:10.1074/jbc.M301504200 [Abstract] [Full Text] [PDF]

Virginia S. Kalogeraki, Silvia Tornaletti, and Philip C. Hanawalt: Transcription Arrest at a Lesion in the Transcribed DNA Strand in Vitro Is Not Affected by a Nearby Lesion in the Opposite Strand
J. Biol. Chem. 2003 278: 19558-19564. First Published on March 19, 2003; doi:10.1074/jbc.M301060200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Shuwen Wang and Jiyue Zhu: Evidence for a Relief of Repression Mechanism for Activation of the Human Telomerase Reverse Transcriptase Promoter
J. Biol. Chem. 2003 278: 18842-18850. First Published on February 28, 2003; doi:10.1074/jbc.M209544200 [Abstract] [Full Text] [PDF]

Javier G. De Gaudenzi, Iván D'Orso, and Alberto C. C. Frasch: RNA Recognition Motif-type RNA-binding Proteins in Trypanosoma cruzi Form a Family Involved in the Interaction with Specific Transcripts in Vivo
J. Biol. Chem. 2003 278: 18884-18894. First Published on March 13, 2003; doi:10.1074/jbc.M301756200 [Abstract] [Full Text] [PDF]

Yukio Mukai, Judith K. Davie, and Sharon Y. R. Dent: Physical and Functional Interaction of the Yeast Corepressor Tup1 with mRNA 5'-Triphosphatase
J. Biol. Chem. 2003 278: 18895-18901. First Published on March 13, 2003; doi:10.1074/jbc.M302155200 [Abstract] [Full Text] [PDF]

Sonya Wieler, Jean-Philippe Gagné, Homayoun Vaziri, Guy G. Poirier, and Samuel Benchimol: Poly(ADP-ribose) Polymerase-1 Is a Positive Regulator of the p53-mediated G₁ Arrest Response following Ionizing Radiation
J. Biol. Chem. 2003 278: 18914-18921. First Published on March 17, 2003; doi:10.1074/jbc.M211641200 [Abstract] [Full Text] [PDF]

Iwona Hirschler-Laszkiewicz, Alice H. Cavanaugh, Ayoub Mirza, Mingyue Lun, Qiyue Hu, Tom Smink, and Lawrence I. Rothblum: Rrn3 Becomes Inactivated in the Process of Ribosomal DNA Transcription
J. Biol. Chem. 2003 278: 18953-18959. First Published on March 19, 2003; doi:10.1074/jbc.M301093200 [Abstract] [Full Text] [PDF]

Zhihong Jiang, Hao Tang, Necat Havlioglu, Xiaochun Zhang, Stefan Stamm, Riqiang Yan, and Jane Y. Wu: Mutations in Tau Gene Exon 10 Associated with FTDP-17 Alter the Activity of an Exonic Splicing Enhancer to Interact with Tra2 ${beta}$
J. Biol. Chem. 2003 278: 18997-19007. First Published on March 20, 2003; doi:10.1074/jbc.M301800200 [Abstract] [Full Text] [PDF]

Karanam Balasubramanyam, V. Swaminathan, Anupama Ranganathan, and Tapas K. Kundu: Small Molecule Modulators of Histone Acetyltransferase p300
J. Biol. Chem. 2003 278: 19134-19140. First Published on March 6, 2003; doi:10.1074/jbc.M301580200 [Abstract] [Full Text] [PDF]

Lin Weng, Dirk R. Van Bockstaele, Jan Wauters, Eric Van Marck, Jean Plum, Zwi N. Berneman, and Jozef Merregaert: A Novel Alternative Spliced Chondrolectin Isoform Lacking the Transmembrane Domain Is Expressed during T Cell Maturation
J. Biol. Chem. 2003 278: 19164-19170. First Published on March 5, 2003; doi:10.1074/jbc.M300653200 [Abstract] [Full Text] [PDF]

Amine Nourani, LeAnn Howe, Marilyn G. Pray-Grant, Jerry L. Workman, Patrick A. Grant, and Jacques Côté: Opposite Role of Yeast ING Family Members in p53-dependent Transcriptional Activation
J. Biol. Chem. 2003 278: 19171-19175. First Published on April 2, 2003; doi:10.1074/jbc.C300036200 [Abstract] [Full Text] [PDF]

Jan-Jan Liu, Shin-Chen Hou, and C.-K. James Shen: Erythroid Gene Suppression by NF- ${kappa}$ B
J. Biol. Chem. 2003 278: 19534-19540. First Published on March 17, 2003; doi:10.1074/jbc.M212278200 [Abstract] [Full Text] [PDF]

RNA: Structure Metabolism and Catalysis:

Victor Julian Valdes, Alicia Sampieri, Jorge Sepulveda, and Luis Vaca: Using Double-stranded RNA to Prevent in Vitro and in Vivo Viral Infections by Recombinant Baculovirus
J. Biol. Chem. 2003 278: 19317-19324. First Published on March 19, 2003; doi:10.1074/jbc.M212039200 [Abstract] [Full Text] [PDF]

Protein Synthesis Post-Translation Modification and Degradation:

Yechiel Elkabetz, Anat Kerem, Lilach Tencer, Dorit Winitz, Ron R. Kopito, and Shoshana Bar-Nun: Immunoglobulin Light Chains Dictate Vesicular Transport-dependent and -independent Routes for IgM Degradation by the Ubiquitin-Proteasome Pathway
J. Biol. Chem. 2003 278: 18922-18929. First Published on March 18, 2003; doi:10.1074/jbc.M208730200 [Abstract] [Full Text] [PDF]

Tadahiro Goda, Takashi Ishii, Nobushige Nakajo, Noriyuki Sagata, and Hideki Kobayashi: The RRASK Motif in Xenopus Cyclin B2 Is Required for the Substrate Recognition of Cdc25C by the Cyclin B-Cdc2 Complex
J. Biol. Chem. 2003 278: 19032-19037. First Published on March 24, 2003; doi:10.1074/jbc.M300210200 [Abstract] [Full Text] [PDF]

Judianne Davis, Matthew R. Wagner, Weibing Zhang, Feng Xu, and William E. Van Nostrand: Amyloid ${beta}$ -Protein Stimulates the Expression of Urokinase-type Plasminogen Activator (uPA) and Its Receptor (uPAR) in Human Cerebrovascular Smooth Muscle Cells
J. Biol. Chem. 2003 278: 19054-19061. First Published on March 24, 2003; doi:10.1074/jbc.M301398200 [Abstract] [Full Text] [PDF]

J. Paul Chapple and Michael E. Cheetham: The Chaperone Environment at the Cytoplasmic Face of the Endoplasmic Reticulum Can Modulate Rhodopsin Processing and Inclusion Formation
J. Biol. Chem. 2003 278: 19087-19094. First Published on March 6, 2003; doi:10.1074/jbc.M212349200 [Abstract] [Full Text] [PDF] Data Supplement Supplemental Data

Genomics Proteomics and Bioinformatics:

Mohamed T. Ghorbel, Greig Sharman, Marie Leroux, Tanya Barrett, David M. Donovan, Kevin G. Becker, and David Murphy: Microarray Analysis Reveals Interleukin-6 as a Novel Secretory Product of the Hypothalamo-neurohypophyseal System
J. Biol. Chem. 2003 278: 19280-19285. First Published on March 14, 2003; doi:10.1074/jbc.M209902200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Sergio Menéndez, Zeb Khan, David W. Coomber, David P. Lane, Maureen Higgins, Maria M. Koufali, and Sonia Laín: Oligomerization of the Human ARF Tumor Suppressor and Its Response to Oxidative Stress
J. Biol. Chem. 2003 278: 18720-18729. First Published on February 11, 2003; doi:10.1074/jbc.M211007200 [Abstract] [Full Text] [PDF]

Chiara Ciaccio, Antonella Rosati, Giampiero De Sanctis, Federica Sinibaldi, Stefano Marini, Roberto Santucci, Paolo Ascenzi, Karen G. Welinder, and Massimo Coletta: Relationships of Ligand Binding, Redox Properties, and Protonation in Coprinus cinereus Peroxidase
J. Biol. Chem. 2003 278: 18730-18737. First Published on March 5, 2003; doi:10.1074/jbc.M212034200 [Abstract] [Full Text] [PDF]

Christian Tendeng, Evelyne Krin, Olga A. Soutourina, Antoine Marin, Antoine Danchin, and Philippe N. Bertin: A Novel H-NS-like Protein from an Antarctic Psychrophilic Bacterium Reveals a Crucial Role for the N-terminal Domain in Thermal Stability
J. Biol. Chem. 2003 278: 18754-18760. First Published on March 13, 2003; doi:10.1074/jbc.M211766200 [Abstract] [Full Text] [PDF]

Catherine A. McLellan, Deborah A. Raynes, and Vince Guerriero: HspBP1, an Hsp70 Cochaperone, Has Two Structural Domains and Is Capable of Altering the Conformation of the Hsp70 ATPase Domain
J. Biol. Chem. 2003 278: 19017-19022. First Published on March 21, 2003; doi:10.1074/jbc.M301109200 [Abstract] [Full Text] [PDF]

Wanjiang Han and Philipp Christen: Mechanism of the Targeting Action of DnaJ in the DnaK Molecular Chaperone System
J. Biol. Chem. 2003 278: 19038-19043. First Published on March 24, 2003; doi:10.1074/jbc.M300756200 [Abstract] [Full Text] [PDF]

Pius Bischofberger, Wanjiang Han, Bastian Feifel, Hans-Joachim Schönfeld, and Philipp Christen: D-Peptides as Inhibitors of the DnaK/DnaJ/GrpE Chaperone System
J. Biol. Chem. 2003 278: 19044-19047. First Published on March 10, 2003; doi:10.1074/jbc.M300922200 [Abstract] [Full Text] [PDF]

John P. A. Grimshaw, Ilian Jelesarov, Rahel K. Siegenthaler, and Philipp Christen: Thermosensor Action of GrpE: THE DnaK CHAPERONE SYSTEM AT HEAT SHOCK TEMPERATURES
J. Biol. Chem. 2003 278: 19048-19053. First Published on March 14, 2003; doi:10.1074/jbc.M300924200 [Abstract] [Full Text] [PDF]

Tzu-Ping Ko, Jing-Jer Lin, Chih-Yung Hu, Yi-Hsin Hsu, Andrew H.-J. Wang, and Shwu-Huey Liaw: Crystal Structure of Yeast Cytosine Deaminase: INSIGHTS INTO ENZYME MECHANISM AND EVOLUTION
J. Biol. Chem. 2003 278: 19111-19117. First Published on March 13, 2003; doi:10.1074/jbc.M300874200 [Abstract] [Full Text] [PDF]

Jacinta A. Lodge, Timm Maier, Wolfgang Liebl, Volker Hoffmann, and Norbert Sträter: Crystal Structure of Thermotoga maritima ${alpha}$ -Glucosidase AglA Defines a New Clan of NAD⁺-dependent Glycosidases
J. Biol. Chem. 2003 278: 19151-19158. First Published on February 14, 2003; doi:10.1074/jbc.M211626200 [Abstract] [Full Text] [PDF]

Jordi Benach, Insun Lee, William Edstrom, Alexandre P. Kuzin, Yiwen Chiang, Thomas B. Acton, Gaetano T. Montelione, and John F. Hunt: The 2.3-Å Crystal Structure of the Shikimate 5-Dehydrogenase Orthologue YdiB from Escherichia coli Suggests a Novel Catalytic Environment for an NAD-dependent Dehydrogenase
J. Biol. Chem. 2003 278: 19176-19182. First Published on March 6, 2003; doi:10.1074/jbc.M301348200 [Abstract] [Full Text] [PDF]

Hiromi Imamura, Shinya Fushinobu, Masaki Yamamoto, Takashi Kumasaka, Beong-Sam Jeon, Takayoshi Wakagi, and Hiroshi Matsuzawa: Crystal Structures of 4- ${alpha}$ -Glucanotransferase from Thermococcus litoralis and Its Complex with an Inhibitor
J. Biol. Chem. 2003 278: 19378-19386. First Published on March 4, 2003; doi:10.1074/jbc.M213134200 [Abstract] [Full Text] [PDF]

Satoshi Sogabe, Ayumi Yoshizumi, Takaaki A. Fukami, Yasuhiko Shiratori, Sakayu Shimizu, Hiroshi Takagi, Shigeru Nakamori, and Masaru Wada: The Crystal Structure and Stereospecificity of Levodione Reductase from Corynebacterium aquaticum M-13
J. Biol. Chem. 2003 278: 19387-19395. First Published on March 5, 2003; doi:10.1074/jbc.M208146200 [Abstract] [Full Text] [PDF]

Francisco J. Enguita, Lígia O. Martins, Adriano O. Henriques, and Maria Arménia Carrondo: Crystal Structure of a Bacterial Endospore Coat Component: A LACCASE WITH ENHANCED THERMOSTABILITY PROPERTIES
J. Biol. Chem. 2003 278: 19416-19425. First Published on March 13, 2003; doi:10.1074/jbc.M301251200 [Abstract] [Full Text] [PDF]

Gurvan Michel, Aleksander W. Roszak, Véronique Sauvé, John Maclean, Allan Matte, John R. Coggins, Miroslaw Cygler, and Adrian J. Lapthorn: Structures of Shikimate Dehydrogenase AroE and Its Paralog YdiB: A COMMON STRUCTURAL FRAMEWORK FOR DIFFERENT ACTIVITIES
J. Biol. Chem. 2003 278: 19463-19472. First Published on March 12, 2003; doi:10.1074/jbc.M300794200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

M. Lucia Bianconi: Calorimetric Determination of Thermodynamic Parameters of Reaction Reveals Different Enthalpic Compensations of the Yeast Hexokinase Isozymes
J. Biol. Chem. 2003 278: 18709-18713. First Published on February 28, 2003; doi:10.1074/jbc.M211103200 [Abstract] [Full Text] [PDF]

Christine Dörr, Melanie Zaparty, Britta Tjaden, Henner Brinkmann, and Bettina Siebers: The Hexokinase of the Hyperthermophile Thermoproteus tenax: ATP-DEPENDENT HEXOKINASES AND ADP-DEPENDENT GLUCOKINASES, TWO ALTERNATIVES FOR GLUCOSE PHOSPHORYLATION IN ARCHAEA
J. Biol. Chem. 2003 278: 18744-18753. First Published on March 7, 2003; doi:10.1074/jbc.M301914200 [Abstract] [Full Text] [PDF]

Eftychia Pinakoulaki, Ute Pfitzner, Bernd Ludwig, and Constantinos Varotsis: Direct Detection of Fe(IV)=O Intermediates in the Cytochrome aa₃ Oxidase from Paracoccus denitrificans/H₂O₂ Reaction
J. Biol. Chem. 2003 278: 18761-18766. First Published on March 13, 2003; doi:10.1074/jbc.M211925200 [Abstract] [Full Text] [PDF]

Paulina Wakula, Monique Beullens, Hugo Ceulemans, Willy Stalmans, and Mathieu Bollen: Degeneracy and Function of the Ubiquitous RVXF Motif That Mediates Binding to Protein Phosphatase-1
J. Biol. Chem. 2003 278: 18817-18823. First Published on March 25, 2003; doi:10.1074/jbc.M300175200 [Abstract] [Full Text] [PDF]

Jerry L. Jeffrey, Joy Y. Feng, C. C. Richard Qi, Karen S. Anderson, and Phillip A. Furman: Dioxolane Guanosine 5'-Triphosphate, an Alternative Substrate Inhibitor of Wild-type and Mutant HIV-1 Reverse Transcriptase: STEADY STATE AND PRE-STEADY STATE KINETIC ANALYSES
J. Biol. Chem. 2003 278: 18971-18979. First Published on March 21, 2003; doi:10.1074/jbc.M210113200 [Abstract] [Full Text] [PDF]

Catherine A. Ibarra, Pramit Chowdhury, Jacob W. Petrich, and William M. Atkins: The Anomalous pK_a of Tyr-9 in Glutathione S-Transferase A1-1 Catalyzes Product Release
J. Biol. Chem. 2003 278: 19257-19265. First Published on March 13, 2003; doi:10.1074/jbc.M301566200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Joan Tordjman, Geneviève Chauvet, Joëlle Quette, Elmus G. Beale, Claude Forest, and Bénédicte Antoine: Thiazolidinediones Block Fatty Acid Release by Inducing Glyceroneogenesis in Fat Cells
J. Biol. Chem. 2003 278: 18785-18790. First Published on March 18, 2003; doi:10.1074/jbc.M206999200 [Abstract] [Full Text] [PDF]

Susan Chalmers and David G. Nicholls: The Relationship between Free and Total Calcium Concentrations in the Matrix of Liver and Brain Mitochondria
J. Biol. Chem. 2003 278: 19062-19070. First Published on March 26, 2003; doi:10.1074/jbc.M212661200 [Abstract] [Full Text] [PDF]

Marcus Fehr, Sylvie Lalonde, Ida Lager, Michael W. Wolff, and Wolf B. Frommer: In Vivo Imaging of the Dynamics of Glucose Uptake in the Cytosol of COS-7 Cells by Fluorescent Nanosensors
J. Biol. Chem. 2003 278: 19127-19133. First Published on March 20, 2003; doi:10.1074/jbc.M301333200 [Abstract] [Full Text] [PDF] Supplemental Data

Xiao-Min Gong, Rufat Agalarov, Klaus Brettel, and Chanoch Carmeli: Control of Electron Transport in Photosystem I by the Iron-Sulfur Cluster F_X in Response to Intra- and Intersubunit Interactions
J. Biol. Chem. 2003 278: 19141-19150. First Published on March 7, 2003; doi:10.1074/jbc.M301808200 [Abstract] [Full Text] [PDF]

Mirko Gastaldelli, Giusy Canino, Roberta Croce, and Roberto Bassi: Xanthophyll Binding Sites of the CP29 (Lhcb4) Subunit of Higher Plant Photosystem II Investigated by Domain Swapping and Mutation Analysis
J. Biol. Chem. 2003 278: 19190-19198. First Published on February 24, 2003; doi:10.1074/jbc.M212125200 [Abstract] [Full Text] [PDF]

Gilbert W. Moeckel, Li Zhang, Agnes B. Fogo, Chuan-Ming Hao, Ambra Pozzi, and Matthew D. Breyer: COX2 Activity Promotes Organic Osmolyte Accumulation and Adaptation of Renal Medullary Interstitial Cells to Hypertonic Stress
J. Biol. Chem. 2003 278: 19352-19357. First Published on March 9, 2003; doi:10.1074/jbc.M302209200 [Abstract] [Full Text] [PDF]

Harshila Patel, Erminia Di Pietro, and Robert E. MacKenzie: Mammalian Fibroblasts Lacking Mitochondrial NAD⁺-dependent Methylenetetrahydrofolate Dehydrogenase-Cyclohydrolase Are Glycine Auxotrophs
J. Biol. Chem. 2003 278: 19436-19441. First Published on March 19, 2003; doi:10.1074/jbc.M301718200 [Abstract] [Full Text] [PDF]

Leonid A. Sazanov, Joe Carroll, Peter Holt, Laurence Toime, and Ian M. Fearnley: A Role for Native Lipids in the Stabilization and Two-dimensional Crystallization of the Escherichia coli NADH-Ubiquinone Oxidoreductase (Complex I)
J. Biol. Chem. 2003 278: 19483-19491. First Published on March 10, 2003; doi:10.1074/jbc.M208959200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Naoto Maeda, Norifumi Kawada, Shuichi Seki, Tetsuo Arakawa, Kazuo Ikeda, Hiroshi Iwao, Hiroaki Okuyama, Jun Hirabayashi, Ken-ichi Kasai, and Katsutoshi Yoshizato: Stimulation of Proliferation of Rat Hepatic Stellate Cells by Galectin-1 and Galectin-3 through Different Intracellular Signaling Pathways
J. Biol. Chem. 2003 278: 18938-18944. First Published on March 19, 2003; doi:10.1074/jbc.M209673200 [Abstract] [Full Text] [PDF]

Michael L. Paine, Hong-Jun Wang, Wen Luo, Paul H. Krebsbach, and Malcolm L. Snead: A Transgenic Animal Model Resembling Amelogenesis Imperfecta Related to Ameloblastin Overexpression
J. Biol. Chem. 2003 278: 19447-19452. First Published on March 25, 2003; doi:10.1074/jbc.M300445200 [Abstract] [Full Text] [PDF]

Adrienne L. Goerges and Matthew A. Nugent: Regulation of Vascular Endothelial Growth Factor Binding and Activity by Extracellular pH
J. Biol. Chem. 2003 278: 19518-19525. First Published on March 11, 2003; doi:10.1074/jbc.M211208200 [Abstract] [Full Text] [PDF]

Wei-Man Wang, Seungbok Lee, Barry M. Steiglitz, Ian C. Scott, Carter C. Lebares, M. Leah Allen, Mitchell C. Brenner, Kazuhiko Takahara, and Daniel S. Greenspan: Transforming Growth Factor- ${beta}$ Induces Secretion of Activated ADAMTS-2: A PROCOLLAGEN III N-PROTEINASE
J. Biol. Chem. 2003 278: 19549-19557. First Published on March 19, 2003; doi:10.1074/jbc.M300767200 [Abstract] [Full Text] [PDF]

Membrane Transport Structure Function and Biogenesis:

Moshit Lindzen, Roman Aizman, Yael Lifshitz, Irina Lubarski, Steven J. D. Karlish, and Haim Garty: Structure-Function Relations of Interactions between Na,K-ATPase, the ${gamma}$ Subunit, and Corticosteroid Hormone-induced Factor
J. Biol. Chem. 2003 278: 18738-18743. First Published on March 7, 2003; doi:10.1074/jbc.M213253200 [Abstract] [Full Text] [PDF]

Marie-Anne Robin, Subbuswamy K. Prabu, Haider Raza, Hindupur K. Anandatheerthavarada, and Narayan G. Avadhani: Phosphorylation Enhances Mitochondrial Targeting of GSTA4-4 through Increased Affinity for Binding to Cytoplasmic Hsp70
J. Biol. Chem. 2003 278: 18960-18970. First Published on March 19, 2003; doi:10.1074/jbc.M301807200 [Abstract] [Full Text] [PDF]

Jürgen Stolz and Martin Vielreicher: Tpn1p, the Plasma Membrane Vitamin B₆ Transporter of Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 18990-18996. First Published on March 20, 2003; doi:10.1074/jbc.M300949200 [Abstract] [Full Text] [PDF]

Aitziber L. Cortajarena, Félix M. Goñi, and Helena Ostolaza: A Receptor-binding Region in Escherichia coli ${alpha}$ -Haemolysin
J. Biol. Chem. 2003 278: 19159-19163. First Published on February 11, 2003; doi:10.1074/jbc.M208552200 [Abstract] [Full Text] [PDF]

Kinnosuke Yahiro, Akihiro Wada, Masaaki Nakayama, Takahiro Kimura, Ken-ichi Ogushi, Takuro Niidome, Haruhiko Aoyagi, Ken-ichi Yoshino, Kazuyoshi Yonezawa, Joel Moss, and Toshiya Hirayama: Protein-tyrosine Phosphatase ${alpha}$ , RPTP ${alpha}$ , Is a Helicobacter pylori VacA Receptor
J. Biol. Chem. 2003 278: 19183-19189. First Published on March 6, 2003; doi:10.1074/jbc.M300117200 [Abstract] [Full Text] [PDF]

Muriel Burnay, Gilles Crambert, Solange Kharoubi-Hess, Käthi Geering, and Jean-Daniel Horisberger: Electrogenicity of Na,K- and H,K-ATPase Activity and Presence of a Positively Charged Amino Acid in the Fifth Transmembrane Segment
J. Biol. Chem. 2003 278: 19237-19244. First Published on March 12, 2003; doi:10.1074/jbc.M300946200 [Abstract] [Full Text] [PDF]

Alice Habermeier, Sabine Wolf, Ursula Martinë, Petra Gräf, and Ellen I. Closs: Two Amino Acid Residues Determine the Low Substrate Affinity of Human Cationic Amino Acid Transporter-2A
J. Biol. Chem. 2003 278: 19492-19499. First Published on March 12, 2003; doi:10.1074/jbc.M210254200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Xia Lin, Min Liang, Yao-Yun Liang, F. Charles Brunicardi, Frauke Melchior, and Xin-Hua Feng: Activation of Transforming Growth Factor- ${beta}$ Signaling by SUMO-1 Modification of Tumor Suppressor Smad4/DPC4
J. Biol. Chem. 2003 278: 18714-18719. First Published on March 5, 2003; doi:10.1074/jbc.M302243200 [Abstract] [Full Text] [PDF]

Stephanie L. Borgland, Mark Connor, Peregrine B. Osborne, John B. Furness, and MacDonald J. Christie: Opioid Agonists Have Different Efficacy Profiles for G Protein Activation, Rapid Desensitization, and Endocytosis of Mu-opioid Receptors
J. Biol. Chem. 2003 278: 18776-18784. First Published on March 17, 2003; doi:10.1074/jbc.M300525200 [Abstract] [Full Text] [PDF]

Ian P. Salt, Valerie A. Morrow, Fiona M. Brandie, John M. C. Connell, and John R. Petrie: High Glucose Inhibits Insulin-stimulated Nitric Oxide Production without Reducing Endothelial Nitric-oxide Synthase Ser¹¹⁷⁷ Phosphorylation in Human Aortic Endothelial Cells
J. Biol. Chem. 2003 278: 18791-18797. First Published on March 18, 2003; doi:10.1074/jbc.M210618200 [Abstract] [Full Text] [PDF]

Shailaja Uttamsingh, Cong S. Zong, and Lu-Hai Wang: Matrix-independent Activation of Phosphatidylinositol 3-Kinase, Stat3, and Cyclin A-associated Cdk2 Is Essential for Anchorage-independent Growth of v-Ros-transformed Chicken Embryo Fibroblasts
J. Biol. Chem. 2003 278: 18798-18810. First Published on March 18, 2003; doi:10.1074/jbc.M211522200 [Abstract] [Full Text] [PDF]

Rebecca Ley, Kathryn Balmanno, Kathryn Hadfield, Claire Weston, and Simon J. Cook: Activation of the ERK1/2 Signaling Pathway Promotes Phosphorylation and Proteasome-dependent Degradation of the BH3-only Protein, Bim
J. Biol. Chem. 2003 278: 18811-18816. First Published on March 19, 2003; doi:10.1074/jbc.M301010200 [Abstract] [Full Text] [PDF]

Rachel J. Buchsbaum, Beth A. Connolly, and Larry A. Feig: Regulation of p70 S6 Kinase by Complex Formation between the Rac Guanine Nucleotide Exchange Factor (Rac-GEF) Tiam1 and the Scaffold Spinophilin
J. Biol. Chem. 2003 278: 18833-18841. First Published on January 16, 2003; doi:10.1074/jbc.M207876200 [Abstract] [Full Text] [PDF]

Roger C. Hardie, Fernando Martin, Sylwester Chyb, and Padinjat Raghu: Rescue of Light Responses in the Drosophila "Null" Phospholipase C Mutant, norpA^P24, by the Diacylglycerol Kinase Mutant, rdgA, and by Metabolic Inhibition
J. Biol. Chem. 2003 278: 18851-18858. First Published on March 5, 2003; doi:10.1074/jbc.M300310200 [Abstract] [Full Text] [PDF]

Malvyne Rolli-Derkinderen, François Machavoine, Jay M. Baraban, Annabelle Grolleau, Laura Beretta, and Michel Dy: ERK and p38 Inhibit the Expression of 4E-BP1 Repressor of Translation through Induction of Egr-1
J. Biol. Chem. 2003 278: 18859-18867. First Published on March 4, 2003; doi:10.1074/jbc.M211696200 [Abstract] [Full Text] [PDF]

Ashok Kumar, Alan J. Knox, and Aladin M. Boriek: CCAAT/Enhancer-binding Protein and Activator Protein-1 Transcription Factors Regulate the Expression of Interleukin-8 through the Mitogen-activated Protein Kinase Pathways in Response to Mechanical Stretch of Human Airway Smooth Muscle Cells
J. Biol. Chem. 2003 278: 18868-18876. First Published on March 13, 2003; doi:10.1074/jbc.M212777200 [Abstract] [Full Text] [PDF]

Anders Bergqvist, Sara Sundström, Lina Y. Dimberg, Erik Gylfe, and Maria G. Masucci: The Hepatitis C Virus Core Protein Modulates T Cell Responses by Inducing Spontaneous and Altering T-cell Receptor-triggered Ca²⁺ Oscillations
J. Biol. Chem. 2003 278: 18877-18883. First Published on March 13, 2003; doi:10.1074/jbc.M300185200 [Abstract] [Full Text] [PDF]

Yao Huang, Sung-Oh Kim, Jing Jiang, and Stuart J. Frank: Growth Hormone-induced Phosphorylation of Epidermal Growth Factor (EGF) Receptor in 3T3-F442A Cells: MODULATION OF EGF-INDUCED TRAFFICKING AND SIGNALING
J. Biol. Chem. 2003 278: 18902-18913. First Published on March 14, 2003; doi:10.1074/jbc.M300939200 [Abstract] [Full Text] [PDF]

Haruhiko Tokuda, Atsushi Harada, Kouseki Hirade, Hiroyuki Matsuno, Hidenori Ito, Kanefusa Kato, Yutaka Oiso, and Osamu Kozawa: Incadronate Amplifies Prostaglandin F₂-induced Vascular Endothelial Growth Factor Synthesis in Osteoblasts: ENHANCEMENT OF MAPK ACTIVITY
J. Biol. Chem. 2003 278: 18930-18937. First Published on March 19, 2003; doi:10.1074/jbc.M209159200 [Abstract] [Full Text] [PDF]

Irute Meskiene, Emmanuel Baudouin, Alois Schweighofer, Aneta Liwosz, Claudia Jonak, Pedro L. Rodriguez, Heinrich Jelinek, and Heribert Hirt: Stress-induced Protein Phosphatase 2C Is a Negative Regulator of a Mitogen-activated Protein Kinase
J. Biol. Chem. 2003 278: 18945-18952. First Published on March 19, 2003; doi:10.1074/jbc.M300878200 [Abstract] [Full Text] [PDF]

Marty W. Mayo, Chadrick E. Denlinger, Robert M. Broad, Fan Yeung, Eugene T. Reilly, Yang Shi, and David R. Jones: Ineffectiveness of Histone Deacetylase Inhibitors to Induce Apoptosis Involves the Transcriptional Activation of NF- ${kappa}$ B through the Akt Pathway
J. Biol. Chem. 2003 278: 18980-18989. First Published on March 20, 2003; doi:10.1074/jbc.M211695200 [Abstract] [Full Text] [PDF]

Andrea Pace, Luis J. García-Marin, Jose A. Tapia, María J. Bragado, and Robert T. Jensen: Phosphospecific Site Tyrosine Phosphorylation of p125^FAK and Proline-rich Kinase 2 Is Differentially Regulated by Cholecystokinin Receptor Type A Activation in Pancreatic Acini
J. Biol. Chem. 2003 278: 19008-19016. First Published on March 21, 2003; doi:10.1074/jbc.M300832200 [Abstract] [Full Text] [PDF]

Shawn M. Ellerbroek, Krister Wennerberg, and Keith Burridge: Serine Phosphorylation Negatively Regulates RhoA in Vivo
J. Biol. Chem. 2003 278: 19023-19031. First Published on March 24, 2003; doi:10.1074/jbc.M213066200 [Abstract] [Full Text] [PDF]

Michinori Mutsuda, Klaus-Peter Michel, Xiaofan Zhang, Beronda L. Montgomery, and Susan S. Golden: Biochemical Properties of CikA, an Unusual Phytochrome-like Histidine Protein Kinase That Resets the Circadian Clock in Synechococcus elongatus PCC 7942
J. Biol. Chem. 2003 278: 19102-19110. First Published on March 7, 2003; doi:10.1074/jbc.M213255200 [Abstract] [Full Text] [PDF]

Bukhtiar H. Shah, M. Parvaiz Farshori, Anokhi Jambusaria, and Kevin J. Catt: Roles of Src and Epidermal Growth Factor Receptor Transactivation in Transient and Sustained ERK1/2 Responses to Gonadotropin-releasing Hormone Receptor Activation
J. Biol. Chem. 2003 278: 19118-19126. First Published on March 17, 2003; doi:10.1074/jbc.M212932200 [Abstract] [Full Text] [PDF]

Sandip K. Mishra, Abhijit Mazumdar, Ratna K. Vadlamudi, Feng Li, Rui-An Wang, Wei Yu, V. Craig Jordan, Richard J. Santen, and Rakesh Kumar: MICoA, a Novel Metastasis-associated Protein 1 (MTA1) Interacting Protein Coactivator, Regulates Estrogen Receptor- ${alpha}$ Transactivation Functions
J. Biol. Chem. 2003 278: 19209-19219. First Published on March 14, 2003; doi:10.1074/jbc.M301968200 [Abstract] [Full Text] [PDF]

Céline Auzanneau, Vincent Thoreau, Alain Kitzis, and Frédéric Becq: A Novel Voltage-dependent Chloride Current Activated by Extracellular Acidic pH in Cultured Rat Sertoli Cells
J. Biol. Chem. 2003 278: 19230-19236. First Published on March 11, 2003; doi:10.1074/jbc.M301096200 [Abstract] [Full Text] [PDF]

Abdellah Mansouri, Lon D. Ridgway, Anita L. Korapati, Qingxiu Zhang, Ling Tian, Yibin Wang, Zahid H. Siddik, Gordon B. Mills, and François X. Claret: Sustained Activation of JNK/p38 MAPK Pathways in Response to Cisplatin Leads to Fas Ligand Induction and Cell Death in Ovarian Carcinoma Cells
J. Biol. Chem. 2003 278: 19245-19256. First Published on March 12, 2003; doi:10.1074/jbc.M208134200 [Abstract] [Full Text] [PDF]

Kylie A. Hotchkiss, Anthony W. Ashton, and Edward L. Schwartz: Thymidine Phosphorylase and 2-Deoxyribose Stimulate Human Endothelial Cell Migration by Specific Activation of the Integrins ${alpha}$ ₅ ${beta}$ ₁ and ${alpha}$ _V ${beta}$ ₃
J. Biol. Chem. 2003 278: 19272-19279. First Published on March 13, 2003; doi:10.1074/jbc.M212670200 [Abstract] [Full Text] [PDF]

Yu-Chi Chiang, Shu-Chun Teng, Yi-Ning Su, Fon-Jou Hsieh, and Kou-Juey Wu: c-Myc Directly Regulates the Transcription of the NBS1 Gene Involved in DNA Double-strand Break Repair
J. Biol. Chem. 2003 278: 19286-19291. First Published on March 13, 2003; doi:10.1074/jbc.M212043200 [Abstract] [Full Text] [PDF]

Tara L. Baker, Hui Zheng, Joy Walker, Jonathan L. Coloff, and Janice E. Buss: Distinct Rates of Palmitate Turnover on Membrane-bound Cellular and Oncogenic H-Ras
J. Biol. Chem. 2003 278: 19292-19300. First Published on March 17, 2003; doi:10.1074/jbc.M206956200 [Abstract] [Full Text] [PDF]

Abel Hiol, Penelope C. Davey, James L. Osterhout, Abdul A. Waheed, Elizabeth R. Fischer, Ching-Kang Chen, Graeme Milligan, Kirk M. Druey, and Teresa L. Z. Jones: Palmitoylation Regulates Regulators of G-protein Signaling (RGS) 16 Function: I. MUTATION OF AMINO-TERMINAL CYSTEINE RESIDUES ON RGS16 PREVENTS ITS TARGETING TO LIPID RAFTS AND PALMITOYLATION OF AN INTERNAL CYSTEINE RESIDUE
J. Biol. Chem. 2003 278: 19301-19308. First Published on March 17, 2003; doi:10.1074/jbc.M210123200 [Abstract] [Full Text] [PDF]

James L. Osterhout, Abdul A. Waheed, Abel Hiol, Richard J. Ward, Penelope C. Davey, Lylia Nini, Jiun Wang, Graeme Milligan, Teresa L. Z. Jones, and Kirk M. Druey: Palmitoylation Regulates Regulator of G-protein Signaling (RGS) 16 Function: II. PALMITOYLATION OF A CYSTEINE RESIDUE IN THE RGS BOX IS CRITICAL FOR RGS16 GTPase ACCELERATING ACTIVITY AND REGULATION OF G_i-COUPLED SIGNALING
J. Biol. Chem. 2003 278: 19309-19316. First Published on March 17, 2003; doi:10.1074/jbc.M210124200 [Abstract] [Full Text] [PDF]

Tzong-Shyuan Lee, Hui-Ling Tsai, and Lee-Young Chau: Induction of Heme Oxygenase-1 Expression in Murine Macrophages Is Essential for the Anti-inflammatory Effect of Low Dose 15-Deoxy- ${Delta}$ ^12,14-prostaglandin J₂
J. Biol. Chem. 2003 278: 19325-19330. First Published on March 17, 2003; doi:10.1074/jbc.M300498200 [Abstract] [Full Text] [PDF]

Dario Diviani, Anne-Laure Lattion, Liliane Abuin, Olivier Staub, and Susanna Cotecchia: The Adaptor Complex 2 Directly Interacts with the ${alpha}$ _1b-Adrenergic Receptor and Plays a Role in Receptor Endocytosis
J. Biol. Chem. 2003 278: 19331-19340. First Published on March 18, 2003; doi:10.1074/jbc.M302110200 [Abstract] [Full Text] [PDF]

Jungyeon Won, Doo Yeon Kim, Muhnho La, Doyeun Kim, Gary G. Meadows, and Cheol O. Joe: Cleavage of 14-3-3 Protein by Caspase-3 Facilitates Bad Interaction with Bcl-x(L) during Apoptosis
J. Biol. Chem. 2003 278: 19347-19351. First Published on March 25, 2003; doi:10.1074/jbc.M213098200 [Abstract] [Full Text] [PDF]

William Andrew Holtz and Karen Laurel O'Malley: Parkinsonian Mimetics Induce Aspects of Unfolded Protein Response in Death of Dopaminergic Neurons
J. Biol. Chem. 2003 278: 19367-19377. First Published on February 21, 2003; doi:10.1074/jbc.M211821200 [Abstract] [Full Text] [PDF]

Áine Kelly, Emily Vereker, Yvonne Nolan, Marcella Brady, Claire Barry, Christine E. Loscher, Kingston H. G. Mills, and Marina A. Lynch: Activation of p38 Plays a Pivotal Role in the Inhibitory Effect of Lipopolysaccharide and Interleukin-1 ${beta}$ on Long Term Potentiation in Rat Dentate Gyrus
J. Biol. Chem. 2003 278: 19453-19462. First Published on February 27, 2003; doi:10.1074/jbc.M301938200 [Abstract] [Full Text] [PDF]

Maria Waldhoer, Paola Casarosa, Mette M. Rosenkilde, Martine J. Smit, Rob Leurs, Jennifer L. Whistler, and Thue W. Schwartz: The Carboxyl Terminus of Human Cytomegalovirus-encoded 7 Transmembrane Receptor US28 Camouflages Agonism by Mediating Constitutive Endocytosis
J. Biol. Chem. 2003 278: 19473-19482. First Published on March 18, 2003; doi:10.1074/jbc.M213179200 [Abstract] [Full Text] [PDF]

Shujuan Chen, Nghia Nguyen, Kumiko Tamura, Michael Karin, and Robert H. Tukey: The Role of the Ah Receptor and p38 in Benzo[a]pyrene-7,8-dihydrodiol and Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced Apoptosis
J. Biol. Chem. 2003 278: 19526-19533. First Published on March 12, 2003; doi:10.1074/jbc.M300780200 [Abstract] [Full Text] [PDF]

David C. Budd, John McDonald, Nita Emsley, Kelvin Cain, and Andrew B. Tobin: The C-terminal Tail of the M₃-muscarinic Receptor Possesses Anti-apoptotic Properties
J. Biol. Chem. 2003 278: 19565-19573. First Published on March 20, 2003; doi:10.1074/jbc.M211670200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Kristen A. Johnson, Deborah van Etten, Nisha Nanda, Robert M. Graham, and Robert A. Terkeltaub: Distinct Transglutaminase 2-independent and Transglutaminase 2-dependent Pathways Mediate Articular Chondrocyte Hypertrophy
J. Biol. Chem. 2003 278: 18824-18832. First Published on February 26, 2003; doi:10.1074/jbc.M301055200 [Abstract] [Full Text] [PDF]

Jacques-Emmanuel Guidotti, Olivier Brégerie, Aude Robert, Pascale Debey, Christian Brechot, and Chantal Desdouets: Liver Cell Polyploidization: A Pivotal Role for Binuclear Hepatocytes
J. Biol. Chem. 2003 278: 19095-19101. First Published on March 7, 2003; doi:10.1074/jbc.M300982200 [Abstract] [Full Text] [PDF] Supplemental Movies

Kanyan Xiao, David F. Allison, Margaret D. Kottke, Susan Summers, George P. Sorescu, Victor Faundez, and Andrew P. Kowalczyk: Mechanisms of VE-cadherin Processing and Degradation in Microvascular Endothelial Cells
J. Biol. Chem. 2003 278: 19199-19208. First Published on March 6, 2003; doi:10.1074/jbc.M211746200 [Abstract] [Full Text] [PDF]

Eunhye Park, Moonseok Na, Jeonghoon Choi, Seho Kim, Jae-Ran Lee, Jiyoung Yoon, Dongeun Park, Morgan Sheng, and Eunjoon Kim: The Shank Family of Postsynaptic Density Proteins Interacts with and Promotes Synaptic Accumulation of the ${beta}$ PIX Guanine Nucleotide Exchange Factor for Rac1 and Cdc42
J. Biol. Chem. 2003 278: 19220-19229. First Published on March 7, 2003; doi:10.1074/jbc.M301052200 [Abstract] [Full Text] [PDF]

Gina-Marie Barletta, Iulia A. Kovari, Rakesh K. Verma, Dontscho Kerjaschki, and Lawrence B. Holzman: Nephrin and Neph1 Co-localize at the Podocyte Foot Process Intercellular Junction and Form cis Hetero-oligomers
J. Biol. Chem. 2003 278: 19266-19271. First Published on March 19, 2003; doi:10.1074/jbc.M301279200 [Abstract] [Full Text] [PDF]

Duanduan Ma, Ping Zhou, and J. William Harbour: Distinct Mechanisms for Regulating the Tumor Suppressor and Antiapoptotic Functions of Rb
J. Biol. Chem. 2003 278: 19358-19366. First Published on March 19, 2003; doi:10.1074/jbc.M301761200 [Abstract] [Full Text] [PDF]

Daisuke Kamei, Makoto Murakami, Yoshihito Nakatani, Yukio Ishikawa, Toshiharu Ishii, and Ichiro Kudo: Potential Role of Microsomal Prostaglandin E Synthase-1 in Tumorigenesis
J. Biol. Chem. 2003 278: 19396-19405. First Published on March 7, 2003; doi:10.1074/jbc.M213290200 [Abstract] [Full Text] [PDF]

Moonil Kim, Joon-Woo Ahn, Un-Ho Jin, Doil Choi, Kyung-Hee Paek, and Hyun-Sook Pai: Activation of the Programmed Cell Death Pathway by Inhibition of Proteasome Function in Plants
J. Biol. Chem. 2003 278: 19406-19415. First Published on March 13, 2003; doi:10.1074/jbc.M210539200 [Abstract] [Full Text] [PDF] Supplemental Data

Carole Moreau, Pierre-François Cartron, Abigail Hunt, Khaled Meflah, Douglas R. Green, Gerard Evan, François M. Vallette, and Philippe Juin: Minimal BH3 Peptides Promote Cell Death by Antagonizing Anti-apoptotic Proteins
J. Biol. Chem. 2003 278: 19426-19435. First Published on March 17, 2003; doi:10.1074/jbc.M209472200 [Abstract] [Full Text] [PDF]

Lucia Cicchillitti, Pasquale Fasanaro, Paolo Biglioli, Maurizio C. Capogrossi, and Fabio Martelli: Oxidative Stress Induces Protein Phosphatase 2A-dependent Dephosphorylation of the Pocket Proteins pRb, p107, and p130
J. Biol. Chem. 2003 278: 19509-19517. First Published on March 5, 2003; doi:10.1074/jbc.M300511200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Qunhua Huang, Nicole Lerner-Marmarosh, Wenyi Che, Shinsuke Ohta, Masaki Osawa, Masanori Yoshizumi, Michael Glassman, Chen Yan, Bradford C. Berk, and Jun-ichi Abe: The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation.
J. Biol. Chem. 2003 278: 19574. [Full Text] [PDF]

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