JBC Focus on PI3-Kinase with Echelon

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Table of Contents: Sep 12 2003; 278 (37)   [Index by Author]  [Cover Figure and Caption]
       Reflections
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Genomics, Proteomics, and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Reflections:

I. R. Lehman
Discovery of DNA Polymerase
J. Biol. Chem. 2003 278: 34733-34738. First Published on June 5, 2003; doi:10.1074/jbc.X300002200 [Full Text] [PDF]  


Accelerated Publications:

Adam Wood, Jessica Schneider, Jim Dover, Mark Johnston, and Ali Shilatifard
The Paf1 Complex Is Essential for Histone Monoubiquitination by the Rad6-Bre1 Complex, Which Signals for Histone Methylation by COMPASS and Dot1p
J. Biol. Chem. 2003 278: 34739-34742. First Published on July 21, 2003; doi:10.1074/jbc.C300269200 [Abstract] [Full Text] [PDF]  

Foon Wu-Baer, Karen Lagrazon, Wei Yuan, and Richard Baer
The BRCA1/BARD1 Heterodimer Assembles Polyubiquitin Chains through an Unconventional Linkage Involving Lysine Residue K6 of Ubiquitin
J. Biol. Chem. 2003 278: 34743-34746. First Published on July 30, 2003; doi:10.1074/jbc.C300249200 [Abstract] [Full Text] [PDF]  

Mousumi Ghosh, Yuri K. Peterson, Stephen M. Lanier, and Alan V. Smrcka
Receptor- and Nucleotide Exchange-independent Mechanisms for Promoting G Protein Subunit Dissociation
J. Biol. Chem. 2003 278: 34747-34750. First Published on July 24, 2003; doi:10.1074/jbc.C300271200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:

Hou Qiang Xu, Eric Deprez, Ai Hua Zhang, Patrick Tauc, Moncef M. Ladjimi, Jean-Claude Brochon, Christian Auclair, and Xu Guang Xi
The Escherichia coli RecQ Helicase Functions as a Monomer
J. Biol. Chem. 2003 278: 34925-34933. First Published on June 12, 2003; doi:10.1074/jbc.M303581200 [Abstract] [Full Text] [PDF]  

Joo Seok Han, Sukhyun Kang, Ho Lee, Hak Kyun Kim, and Deog Su Hwang
Sequential Binding of SeqA to Paired Hemi-methylated GATC Sequences Mediates Formation of Higher Order Complexes
J. Biol. Chem. 2003 278: 34983-34989. First Published on June 24, 2003; doi:10.1074/jbc.M304923200 [Abstract] [Full Text] [PDF]  

Olivier A. Pierrat and Anthony Maxwell
The Action of the Bacterial Toxin Microcin B17: INSIGHT INTO THE CLEAVAGE-RELIGATION REACTION OF DNA GYRASE
J. Biol. Chem. 2003 278: 35016-35023. First Published on June 25, 2003; doi:10.1074/jbc.M304516200 [Abstract] [Full Text] [PDF]  

Stéphane Vispé, Erick L. Y. Ho, Tetsu M. C. Yung, and Masahiko S. Satoh
Double-strand DNA Break Formation Mediated by Flap Endonuclease-1
J. Biol. Chem. 2003 278: 35279-35285. First Published on June 27, 2003; doi:10.1074/jbc.M303448200 [Abstract] [Full Text] [PDF]  

Sara K. Binz, Ye Lao, David F. Lowry, and Marc S. Wold
The Phosphorylation Domain of the 32-kDa Subunit of Replication Protein A (RPA) Modulates RPA-DNA Interactions: EVIDENCE FOR AN INTERSUBUNIT INTERACTION
J. Biol. Chem. 2003 278: 35584-35591. First Published on June 20, 2003; doi:10.1074/jbc.M305388200 [Abstract] [Full Text] [PDF]  

Silvia Tornaletti, Steve M. Patrick, John J. Turchi, and Philip C. Hanawalt
Behavior of T7 RNA Polymerase and Mammalian RNA Polymerase II at Site-specific Cisplatin Adducts in the Template DNA
J. Biol. Chem. 2003 278: 35791-35797. First Published on June 26, 2003; doi:10.1074/jbc.M305394200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Yaofeng Zhao, Imre Kacskovics, Hodjattallah Rabbani, and Lennart Hammarström
Physical Mapping of the Bovine Immunoglobulin Heavy Chain Constant Region Gene Locus
J. Biol. Chem. 2003 278: 35024-35032. First Published on June 26, 2003; doi:10.1074/jbc.M301337200 [Abstract] [Full Text] [PDF]  

Daniel M. Kemp, Julia C. Lin, and Joel F. Habener
Regulation of Pax4 Paired Homeodomain Gene by Neuron-restrictive Silencer Factor
J. Biol. Chem. 2003 278: 35057-35062. First Published on June 26, 2003; doi:10.1074/jbc.M305891200 [Abstract] [Full Text] [PDF]  

Beatrice Cardinali, Claudia Carissimi, Paolo Gravina, and Paola Pierandrei-Amaldi
La Protein Is Associated with Terminal Oligopyrimidine mRNAs in Actively Translating Polysomes
J. Biol. Chem. 2003 278: 35145-35151. First Published on July 1, 2003; doi:10.1074/jbc.M300722200 [Abstract] [Full Text] [PDF]  

Zheng Chen and James L. Manley
In Vivo Functional Analysis of the Histone 3-like TAF9 and a TAF9-related Factor, TAF9L
J. Biol. Chem. 2003 278: 35172-35183. First Published on July 1, 2003; doi:10.1074/jbc.M304241200 [Abstract] [Full Text] [PDF]  

Chi Zhang, Diane R. Dowd, Ada Staal, Chun Gu, Jane B. Lian, Andre J. van Wijnen, Gary S. Stein, and Paul N. MacDonald
Nuclear Coactivator-62 kDa/Ski-interacting Protein Is a Nuclear Matrix-associated Coactivator That May Couple Vitamin D Receptor-mediated Transcription and RNA Splicing
J. Biol. Chem. 2003 278: 35325-35336. First Published on July 2, 2003; doi:10.1074/jbc.M305191200 [Abstract] [Full Text] [PDF]  

Haiying He, Fabrice Soncin, Nicholas Grammatikakis, Youlin Li, Aliki Siganou, Jianlin Gong, Steven A. Brown, Robert E. Kingston, and Stuart K. Calderwood
Elevated Expression of Heat Shock Factor (HSF) 2A Stimulates HSF1-induced Transcription during Stress
J. Biol. Chem. 2003 278: 35465-35475. First Published on June 16, 2003; doi:10.1074/jbc.M304663200 [Abstract] [Full Text] [PDF]  

Annette Lasham, Stephanie Moloney, Tracy Hale, Craig Homer, You Fang Zhang, J. Greg Murison, Antony W. Braithwaite, and James Watson
The Y-box-binding Protein, YB1, Is a Potential Negative Regulator of the p53 Tumor Suppressor
J. Biol. Chem. 2003 278: 35516-35523. First Published on June 30, 2003; doi:10.1074/jbc.M303920200 [Abstract] [Full Text] [PDF]  

Mario deFelice, Daniel Silberschmidt, Roberto DiLauro, Yan Xu, Susan E. Wert, Timothy E. Weaver, Cindy J. Bachurski, Jean C. Clark, and Jeffrey A. Whitsett
TTF-1 Phosphorylation Is Required for Peripheral Lung Morphogenesis, Perinatal Survival, and Tissue-specific Gene Expression
J. Biol. Chem. 2003 278: 35574-35583. First Published on June 26, 2003; doi:10.1074/jbc.M304885200 [Abstract] [Full Text] [PDF]  

Jun Hirayama, Haruki Nakamura, Tomoko Ishikawa, Yuri Kobayashi, and Takeshi Todo
Functional and Structural Analyses of Cryptochrome: VERTEBRATE CRY REGIONS RESPONSIBLE FOR INTERACTION WITH THE CLOCK:BMAL1 HETERODIMER AND ITS NUCLEAR LOCALIZATION
J. Biol. Chem. 2003 278: 35620-35628. First Published on June 27, 2003; doi:10.1074/jbc.M305028200 [Abstract] [Full Text] [PDF]  

Takashi Umehara and Masami Horikoshi
Transcription Initiation Factor IID-interactive Histone Chaperone CIA-II Implicated in Mammalian Spermatogenesis
J. Biol. Chem. 2003 278: 35660-35667. First Published on July 2, 2003; doi:10.1074/jbc.M303549200 [Abstract] [Full Text] [PDF]  

Graciela Piwien Pilipuk, Mario D. Galigniana, and Jessica Schwartz
Subnuclear Localization of C/EBP{beta} Is Regulated by Growth Hormone and Dependent on MAPK
J. Biol. Chem. 2003 278: 35668-35677. First Published on June 23, 2003; doi:10.1074/jbc.M305182200 [Abstract] [Full Text] [PDF]  

Elisabeth Fayard, Kristina Schoonjans, Jean-Sébastien Annicotte, and Johan Auwerx
Liver Receptor Homolog 1 Controls the Expression of Carboxyl Ester Lipase
J. Biol. Chem. 2003 278: 35725-35731. First Published on July 9, 2003; doi:10.1074/jbc.M302370200 [Abstract] [Full Text] [PDF]  

Guangyong Li, Kunfan Liu, Stephen A. Baldwin, and Daowen Wang
Equilibrative Nucleoside Transporters of Arabidopsis thaliana: cDNA CLONING, EXPRESSION PATTERN, AND ANALYSIS OF TRANSPORT ACTIVITIES
J. Biol. Chem. 2003 278: 35732-35742. First Published on June 16, 2003; doi:10.1074/jbc.M304768200 [Abstract] [Full Text] [PDF]  

Sudhakar Ammanamanchi, James W. Freeman, and Michael G. Brattain
Acetylated Sp3 Is a Transcriptional Activator
J. Biol. Chem. 2003 278: 35775-35780. First Published on June 30, 2003; doi:10.1074/jbc.M305961200 [Abstract] [Full Text] [PDF]  

Xiao-Hong Li and David E. Ong
Cellular Retinoic Acid-binding Protein II Gene Expression Is Directly Induced by Estrogen, but Not Retinoic Acid, in Rat Uterus
J. Biol. Chem. 2003 278: 35819-35825. First Published on July 3, 2003; doi:10.1074/jbc.M302551200 [Abstract] [Full Text] [PDF]  


RNA: Structure, Metabolism, and Catalysis:

Antonio M. Estévez, Ben Lehner, Christopher M. Sanderson, Thomas Ruppert, and Christine Clayton
The Roles of Intersubunit Interactions in Exosome Stability
J. Biol. Chem. 2003 278: 34943-34951. First Published on June 23, 2003; doi:10.1074/jbc.M305333200 [Abstract] [Full Text] [PDF]  

Jacoba G. Slagter-Jäger and E. Gerhart H. Wagner
Loop Swapping in an Antisense RNA/Target RNA Pair Changes Directionality of Helix Progression
J. Biol. Chem. 2003 278: 35558-35563. First Published on June 20, 2003; doi:10.1074/jbc.M304867200 [Abstract] [Full Text] [PDF]  

Shannon F. Holmes and Dorothy A. Erie
Downstream DNA Sequence Effects on Transcription Elongation: ALLOSTERIC BINDING OF NUCLEOSIDE TRIPHOSPHATES FACILITATES TRANSLOCATION VIA A RATCHET MOTION
J. Biol. Chem. 2003 278: 35597-35608. First Published on June 16, 2003; doi:10.1074/jbc.M304496200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:

Dennis Flierman, Yihong Ye, Min Dai, Vincent Chau, and Tom A. Rapoport
Polyubiquitin Serves as a Recognition Signal, Rather than a Ratcheting Molecule, during Retrotranslocation of Proteins across the Endoplasmic Reticulum Membrane
J. Biol. Chem. 2003 278: 34774-34782. First Published on June 17, 2003; doi:10.1074/jbc.M303360200 [Abstract] [Full Text] [PDF]  

Margo H. Furman, Joana Loureiro, Hidde L. Ploegh, and Domenico Tortorella
Ubiquitinylation of the Cytosolic Domain of a Type I Membrane Protein Is Not Required to Initiate Its Dislocation from the Endoplasmic Reticulum
J. Biol. Chem. 2003 278: 34804-34811. First Published on June 27, 2003; doi:10.1074/jbc.M300913200 [Abstract] [Full Text] [PDF] Supplemental Data  

Jesse Bertinato and Mary R. L'Abbé
Copper Modulates the Degradation of Copper Chaperone for Cu,Zn Superoxide Dismutase by the 26 S Proteosome
J. Biol. Chem. 2003 278: 35071-35078. First Published on June 27, 2003; doi:10.1074/jbc.M302242200 [Abstract] [Full Text] [PDF]  

Beat C. Bornhauser, Per-Anders Olsson, and Dan Lindholm
MSAP Is a Novel MIR-interacting Protein That Enhances Neurite Outgrowth and Increases Myosin Regulatory Light Chain
J. Biol. Chem. 2003 278: 35412-35420. First Published on June 24, 2003; doi:10.1074/jbc.M306271200 [Abstract] [Full Text] [PDF]  

Lynda J. Donald, Oleg V. Krokhin, Harry W. Duckworth, Benjamin Wiseman, Taweewat Deemagarn, Rahul Singh, Jack Switala, Xavi Carpena, Ignacio Fita, and Peter C. Loewen
Characterization of the Catalase-Peroxidase KatG from Burkholderia pseudomallei by Mass Spectrometry
J. Biol. Chem. 2003 278: 35687-35692. First Published on June 29, 2003; doi:10.1074/jbc.M304053200 [Abstract] [Full Text] [PDF]  

Husam A. J. Alwan, Everardus J. J. van Zoelen, and Jeroen E. M. van Leeuwen
Ligand-induced Lysosomal Epidermal Growth Factor Receptor (EGFR) Degradation Is Preceded by Proteasome-dependent EGFR De-ubiquitination
J. Biol. Chem. 2003 278: 35781-35790. First Published on June 26, 2003; doi:10.1074/jbc.M301326200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:

Ameeta K. Agarwal, P. David Rogers, Scott R. Baerson, Melissa R. Jacob, Katherine S. Barker, John D. Cleary, Larry A. Walker, Dale G. Nagle, and Alice M. Clark
Genome-wide Expression Profiling of the Response to Polyene, Pyrimidine, Azole, and Echinocandin Antifungal Agents in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 34998-35015. First Published on June 24, 2003; doi:10.1074/jbc.M306291200 [Abstract] [Full Text] [PDF] Supplemental Data  

Angela Schulz and Torsten Schöneberg
The Structural Evolution of a P2Y-like G-protein-coupled Receptor
J. Biol. Chem. 2003 278: 35531-35541. First Published on June 30, 2003; doi:10.1074/jbc.M303346200 [Abstract] [Full Text] [PDF] Supplemental Data  

Illarion V. Turko and Ferid Murad
Quantitative Protein Profiling in Heart Mitochondria from Diabetic Rats
J. Biol. Chem. 2003 278: 35844-35849. First Published on July 7, 2003; doi:10.1074/jbc.M303139200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Robert J. Chalifour, Richard W. McLaughlin, Louis Lavoie, Céline Morissette, Nadine Tremblay, Marie Boulé, Philippe Sarazin, Dino Stéa, Diane Lacombe, Patrick Tremblay, and Francine Gervais
Stereoselective Interactions of Peptide Inhibitors with the {beta}-Amyloid Peptide
J. Biol. Chem. 2003 278: 34874-34881. First Published on July 2, 2003; doi:10.1074/jbc.M212694200 [Abstract] [Full Text] [PDF]  

Gal Bitan, Sabrina S. Vollers, and David B. Teplow
Elucidation of Primary Structure Elements Controlling Early Amyloid {beta}-Protein Oligomerization
J. Biol. Chem. 2003 278: 34882-34889. First Published on July 2, 2003; doi:10.1074/jbc.M300825200 [Abstract] [Full Text] [PDF] Supplemental Data  

Reija Hieta, Liisa Kukkola, Perttu Permi, Päivi Pirilä, Kari I. Kivirikko, Ilkka Kilpeläinen, and Johanna Myllyharju
The Peptide-Substrate-binding Domain of Human Collagen Prolyl 4-Hydroxylases: BACKBONE ASSIGNMENTS, SECONDARY STRUCTURE, AND BINDING OF PROLINE-RICH PEPTIDES
J. Biol. Chem. 2003 278: 34966-34974. First Published on June 24, 2003; doi:10.1074/jbc.M303624200 [Abstract] [Full Text] [PDF]  

Stanley C. Kwok and Robert S. Hodges
Clustering of Large Hydrophobes in the Hydrophobic Core of Two-stranded {alpha}-Helical Coiled-Coils Controls Protein Folding and Stability
J. Biol. Chem. 2003 278: 35248-35254. First Published on July 3, 2003; doi:10.1074/jbc.M305306200 [Abstract] [Full Text] [PDF]  

Robert Fedic, Michal Zurovec, and Frantisek Sehnal
Correlation between Fibroin Amino Acid Sequence and Physical Silk Properties
J. Biol. Chem. 2003 278: 35255-35264. First Published on June 19, 2003; doi:10.1074/jbc.M305304200 [Abstract] [Full Text] [PDF]  

H. Michael Ellerby, Sannamu Lee, Lisa M. Ellerby, Sylvia Chen, Taira Kiyota, Gabriel del Rio, Gohsuke Sugihara, Yan Sun, Dale E. Bredesen, Wadih Arap, and Renata Pasqualini
An Artificially Designed Pore-forming Protein with Anti-tumor Effects
J. Biol. Chem. 2003 278: 35311-35316. First Published on May 14, 2003; doi:10.1074/jbc.M300474200 [Abstract] [Full Text] [PDF]  

Ariane Schmechel, Hanswalter Zentgraf, Stefan Scheuermann, Guenter Fritz, Rüdiger Pipkorn, Jennifer Reed, Konrad Beyreuther, Thomas A. Bayer, and Gerd Multhaup
Alzheimer {beta}-Amyloid Homodimers Facilitate A{beta} Fibrillization and the Generation of Conformational Antibodies
J. Biol. Chem. 2003 278: 35317-35324. First Published on July 1, 2003; doi:10.1074/jbc.M303547200 [Abstract] [Full Text] [PDF]  

Júlio C. Borges, Hannes Fischer, Aldo F. Craievich, Lee D. Hansen, and Carlos H. I. Ramos
Free Human Mitochondrial GrpE Is a Symmetric Dimer in Solution
J. Biol. Chem. 2003 278: 35337-35344. First Published on July 2, 2003; doi:10.1074/jbc.M305083200 [Abstract] [Full Text] [PDF]  

Masayuki Yamasaki, Nobuyuki Takahashi, and Masaaki Hirose
Crystal Structure of S-ovalbumin as a Non-loop-inserted Thermostabilized Serpin Form
J. Biol. Chem. 2003 278: 35524-35530. First Published on July 1, 2003; doi:10.1074/jbc.M305926200 [Abstract] [Full Text] [PDF]  

Luigi Calzolai and Ralph Zahn
Influence of pH on NMR Structure and Stability of the Human Prion Protein Globular Domain
J. Biol. Chem. 2003 278: 35592-35596. First Published on June 25, 2003; doi:10.1074/jbc.M303005200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Noureddine Atmane, Julien Dairou, Angela Paul, Jean-Marie Dupret, and Fernando Rodrigues-Lima
Redox Regulation of the Human Xenobiotic Metabolizing Enzyme Arylamine N-Acetyltransferase 1 (NAT1): REVERSIBLE INACTIVATION BY HYDROGEN PEROXIDE
J. Biol. Chem. 2003 278: 35086-35092. First Published on June 27, 2003; doi:10.1074/jbc.M303813200 [Abstract] [Full Text] [PDF]  

Bruno Marchand and Matthias Götte
Site-specific Footprinting Reveals Differences in the Translocation Status of HIV-1 Reverse Transcriptase: IMPLICATIONS FOR POLYMERASE TRANSLOCATION AND DRUG RESISTANCE
J. Biol. Chem. 2003 278: 35362-35372. First Published on June 20, 2003; doi:10.1074/jbc.M304262200 [Abstract] [Full Text] [PDF]  

Daohai Zhang, Nan Li, Shee-Mei Lok, Lian-Hui Zhang, and Kunchithapadam Swaminathan
Isomaltulose Synthase (PalI) of Klebsiella sp. LX3: CRYSTAL STRUCTURE AND IMPLICATION OF MECHANISM
J. Biol. Chem. 2003 278: 35428-35434. First Published on June 20, 2003; doi:10.1074/jbc.M302616200 [Abstract] [Full Text] [PDF]  

David J. Stokell, Lynda J. Donald, Robert Maurus, Nham T. Nguyen, Gillian Sadler, Kajal Choudhary, Philip G. Hultin, Gary D. Brayer, and Harry W. Duckworth
Probing the Roles of Key Residues in the Unique Regulatory NADH Binding Site of Type II Citrate Synthase of Escherichia coli
J. Biol. Chem. 2003 278: 35435-35443. First Published on June 23, 2003; doi:10.1074/jbc.M302786200 [Abstract] [Full Text] [PDF]  

James L. Thomas, William L. Duax, Anthony Addlagatta, Stacey Brandt, Robert R. Fuller, and Wendy Norris
Structure/Function Relationships Responsible for Coenzyme Specificity and the Isomerase Activity of Human Type 1 3{beta}-Hydroxysteroid Dehydrogenase/Isomerase
J. Biol. Chem. 2003 278: 35483-35490. First Published on June 27, 2003; doi:10.1074/jbc.M304752200 [Abstract] [Full Text] [PDF]  

Nadaraj Palaniappan, Beom Seok Kim, Yasuyo Sekiyama, Hiroyuki Osada, and Kevin A. Reynolds
Enhancement and Selective Production of Phoslactomycin B, a Protein Phosphatase IIa Inhibitor, through Identification and Engineering of the Corresponding Biosynthetic Gene Cluster
J. Biol. Chem. 2003 278: 35552-35557. First Published on June 20, 2003; doi:10.1074/jbc.M305082200 [Abstract] [Full Text] [PDF]  

Ericka M. Wiebe, Alan R. Stafford, James C. Fredenburgh, and Jeffrey I. Weitz
Mechanism of Catalysis of Inhibition of Factor IXa by Antithrombin in the Presence of Heparin or Pentasaccharide
J. Biol. Chem. 2003 278: 35767-35774. First Published on June 27, 2003; doi:10.1074/jbc.M304803200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Tammy Bohannon Grabar and Brian D. Cain
Integration of b Subunits of Unequal Lengths into F1F0-ATP Synthase
J. Biol. Chem. 2003 278: 34751-34756. First Published on July 2, 2003; doi:10.1074/jbc.M303361200 [Abstract] [Full Text] [PDF]  

Oliver Speer, Sarune Morkunaite-Haimi, Julius Liobikas, Marina Franck, Linn Hensbo, Matts D. Linder, Paavo K. J. Kinnunen, Theo Wallimann, and Ove Eriksson
Rapid Suppression of Mitochondrial Permeability Transition by Methylglyoxal: ROLE OF REVERSIBLE ARGININE MODIFICATION
J. Biol. Chem. 2003 278: 34757-34763. First Published on June 18, 2003; doi:10.1074/jbc.M301990200 [Abstract] [Full Text] [PDF]  

Aneta E. Reszko, Takhar Kasumov, Bradley A. Pierce, France David, Charles L. Hoppel, William C. Stanley, Christine Des Rosiers, and Henri Brunengraber
Assessing the Reversibility of the Anaplerotic Reactions of the Propionyl-CoA Pathway in Heart and Liver
J. Biol. Chem. 2003 278: 34959-34965. First Published on June 24, 2003; doi:10.1074/jbc.M302013200 [Abstract] [Full Text] [PDF]  

Elizabeth Hernández-Urzúa, Catherine E. Mills, Gregory P. White, Martha L. Contreras-Zentella, Edgardo Escamilla, Subhash G. Vasudevan, Jorge Membrillo-Hernández, and Robert K. Poole
Flavohemoglobin Hmp, but Not Its Individual Domains, Confers Protection from Respiratory Inhibition by Nitric Oxide in Escherichia coli
J. Biol. Chem. 2003 278: 34975-34982. First Published on June 24, 2003; doi:10.1074/jbc.M303629200 [Abstract] [Full Text] [PDF]  

Mei Zhang, Xuefeng Su, Eugenia Mileykovskaya, Andrew A. Amoscato, and William Dowhan
Cardiolipin Is Not Required to Maintain Mitochondrial DNA Stability or Cell Viability for Saccharomyces cerevisiae Grown at Elevated Temperatures
J. Biol. Chem. 2003 278: 35204-35210. First Published on July 2, 2003; doi:10.1074/jbc.M306729200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Kelly G. Ten Hagen, Duy T. Tran, Thomas A. Gerken, David S. Stein, and Zhenyu Zhang
Functional Characterization and Expression Analysis of Members of the UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase Family from Drosophila melanogaster
J. Biol. Chem. 2003 278: 35039-35048. First Published on June 26, 2003; doi:10.1074/jbc.M303836200 [Abstract] [Full Text] [PDF]  

Feng Gong, Per Jemth, Martha L. Escobar Galvis, Israel Vlodavsky, Alan Horner, Ulf Lindahl, and Jin-ping Li
Processing of Macromolecular Heparin by Heparanase
J. Biol. Chem. 2003 278: 35152-35158. First Published on July 1, 2003; doi:10.1074/jbc.M300925200 [Abstract] [Full Text] [PDF]  

Paul L. DeAngelis, Leonard C. Oatman, and Daniel F. Gay
Rapid Chemoenzymatic Synthesis of Monodisperse Hyaluronan Oligosaccharides with Immobilized Enzyme Reactors
J. Biol. Chem. 2003 278: 35199-35203. First Published on July 2, 2003; doi:10.1074/jbc.M306431200 [Abstract] [Full Text] [PDF]  

Yu-Teh Li, Karol Maskos, Chau-Wen Chou, Richard B. Cole, and Su-Chen Li
Presence of an Unusual GM2 Derivative, Taurine-conjugated GM2, in Tay-Sachs Brain
J. Biol. Chem. 2003 278: 35286-35291. First Published on June 26, 2003; doi:10.1074/jbc.M306126200 [Abstract] [Full Text] [PDF]  

Nobuaki Maeda, Jue He, Yuki Yajima, Tadahisa Mikami, Kazuyuki Sugahara, and Tomio Yabe
Heterogeneity of the Chondroitin Sulfate Portion of Phosphacan/6B4 Proteoglycan Regulates Its Binding Affinity for Pleiotrophin/Heparin Binding Growth-associated Molecule
J. Biol. Chem. 2003 278: 35805-35811. First Published on July 2, 2003; doi:10.1074/jbc.M305530200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Rhidaya Shrestha, Richard A. Dixon, and Kent D. Chapman
Molecular Identification of a Functional Homologue of the Mammalian Fatty Acid Amide Hydrolase in Arabidopsis thaliana
J. Biol. Chem. 2003 278: 34990-34997. First Published on June 24, 2003; doi:10.1074/jbc.M305613200 [Abstract] [Full Text] [PDF]  

Chester J. Provoda, Ethan M. Stier, and Kyung-Dall Lee
Tumor Cell Killing Enabled by Listeriolysin O-liposome-mediated Delivery of the Protein Toxin Gelonin
J. Biol. Chem. 2003 278: 35102-35108. First Published on June 27, 2003; doi:10.1074/jbc.M305411200 [Abstract] [Full Text] [PDF]  

Frédéric Domergue, Amine Abbadi, Claudia Ott, Thorsten K. Zank, Ulrich Zähringer, and Ernst Heinz
Acyl Carriers Used as Substrates by the Desaturases and Elongases Involved in Very Long-chain Polyunsaturated Fatty Acids Biosynthesis Reconstituted in Yeast
J. Biol. Chem. 2003 278: 35115-35126. First Published on June 30, 2003; doi:10.1074/jbc.M305990200 [Abstract] [Full Text] [PDF]  

F. Gregory Buchanan, Dingzhi Wang, Francesca Bargiacchi, and Raymond N. DuBois
Prostaglandin E2 Regulates Cell Migration via the Intracellular Activation of the Epidermal Growth Factor Receptor
J. Biol. Chem. 2003 278: 35451-35457. First Published on June 24, 2003; doi:10.1074/jbc.M302474200 [Abstract] [Full Text] [PDF]  

David J. Shields, Judith Y. Altarejos, Xu Wang, Luis B. Agellon, and Dennis E. Vance
Molecular Dissection of the S-Adenosylmethionine-binding Site of Phosphatidylethanolamine N-Methyltransferase
J. Biol. Chem. 2003 278: 35826-35836. First Published on July 3, 2003; doi:10.1074/jbc.M306308200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:

Melissa D. Laughery, Matthew L. Todd, and Jack H. Kaplan
Mutational Analysis of {alpha}-{beta} Subunit Interactions in the Delivery of Na,K-ATPase Heterodimers to the Plasma Membrane
J. Biol. Chem. 2003 278: 34794-34803. First Published on June 25, 2003; doi:10.1074/jbc.M302899200 [Abstract] [Full Text] [PDF]  

Hong Yang, Anang A. Shelat, R. Kiplin Guy, Vadiraj S. Gopinath, Tonghui Ma, Kai Du, Gergely L. Lukacs, Alessandro Taddei, Chiara Folli, Nicoletta Pedemonte, Luis J. V. Galietta, and A. S. Verkman
Nanomolar Affinity Small Molecule Correctors of Defective {Delta}F508-CFTR Chloride Channel Gating
J. Biol. Chem. 2003 278: 35079-35085. First Published on June 27, 2003; doi:10.1074/jbc.M303098200 [Abstract] [Full Text] [PDF]  

Sandra Console, Cornelia Marty, Carlos García-Echeverría, Reto Schwendener, and Kurt Ballmer-Hofer
Antennapedia and HIV Transactivator of Transcription (TAT) "Protein Transduction Domains" Promote Endocytosis of High Molecular Weight Cargo upon Binding to Cell Surface Glycosaminoglycans
J. Biol. Chem. 2003 278: 35109-35114. First Published on June 30, 2003; doi:10.1074/jbc.M301726200 [Abstract] [Full Text] [PDF] Supplemental Data  

Alex Stein, Gayatri Vaseduvan, Nicola S. Carter, Buddy Ullman, Scott M. Landfear, and Michael P. Kavanaugh
Equilibrative Nucleoside Transporter Family Members from Leishmania donovani Are Electrogenic Proton Symporters
J. Biol. Chem. 2003 278: 35127-35134. First Published on June 30, 2003; doi:10.1074/jbc.M306188200 [Abstract] [Full Text] [PDF]  

Galya Reuter, Tavan Janvilisri, Henrietta Venter, Sanjay Shahi, Lekshmy Balakrishnan, and Hendrik W. van Veen
The ATP Binding Cassette Multidrug Transporter LmrA and Lipid Transporter MsbA Have Overlapping Substrate Specificities
J. Biol. Chem. 2003 278: 35193-35198. First Published on July 2, 2003; doi:10.1074/jbc.M306226200 [Abstract] [Full Text] [PDF]  

Susmita Samanta, Tulin Ayvaz, Moriama Reyes, Howard A. Shuman, Jue Chen, and Amy L. Davidson
Disulfide Cross-linking Reveals a Site of Stable Interaction between C-terminal Regulatory Domains of the Two MalK Subunits in the Maltose Transport Complex
J. Biol. Chem. 2003 278: 35265-35271. First Published on June 17, 2003; doi:10.1074/jbc.M301171200 [Abstract] [Full Text] [PDF]  

Debjani Mandal, Samuel J. Rulli, and Rajini Rao
Packing Interactions between Transmembrane Helices Alter Ion Selectivity of the Yeast Golgi Ca2+/Mn2+-ATPase PMR1
J. Biol. Chem. 2003 278: 35292-35298. First Published on June 24, 2003; doi:10.1074/jbc.M306166200 [Abstract] [Full Text] [PDF]  

Frank Voncken, Jaap J. van Hellemond, Iris Pfisterer, Alexander Maier, Stephan Hillmer, and Christine Clayton
Depletion of GIM5 Causes Cellular Fragility, a Decreased Glycosome Number, and Reduced Levels of Ether-linked Phospholipids in Trypanosomes
J. Biol. Chem. 2003 278: 35299-35310. First Published on June 26, 2003; doi:10.1074/jbc.M301811200 [Abstract] [Full Text] [PDF]  

Cornelia Spycher, Nectarios Klonis, Tobias Spielmann, Erwin Kump, Sylvia Steiger, Leann Tilley, and Hans-Peter Beck
MAHRP-1, a Novel Plasmodium falciparum Histidine-rich Protein, Binds Ferriprotoporphyrin IX and Localizes to the Maurer's Clefts
J. Biol. Chem. 2003 278: 35373-35383. First Published on June 18, 2003; doi:10.1074/jbc.M305851200 [Abstract] [Full Text] [PDF]  

Christophe Danelon, Thérèse Brando, and Mathias Winterhalter
Probing the Orientation of Reconstituted Maltoporin Channels at the Single-protein Level
J. Biol. Chem. 2003 278: 35542-35551. First Published on June 30, 2003; doi:10.1074/jbc.M305434200 [Abstract] [Full Text] [PDF]  

Kazuko Miyakawa and Toru Imamura
Secretion of FGF-16 Requires an Uncleaved Bipartite Signal Sequence
J. Biol. Chem. 2003 278: 35718-35724. First Published on July 8, 2003; doi:10.1074/jbc.M300690200 [Abstract] [Full Text] [PDF]  

Brian P. Delisle, Corey L. Anderson, Ravi C. Balijepalli, Blake D. Anson, Timothy J. Kamp, and Craig T. January
Thapsigargin Selectively Rescues the Trafficking Defective LQT2 Channels G601S and F805C
J. Biol. Chem. 2003 278: 35749-35754. First Published on July 1, 2003; doi:10.1074/jbc.M305787200 [Abstract] [Full Text] [PDF]  

Rita Padányi, Katalin Pászty, Alan R. Penheiter, Adelaida G. Filoteo, John T. Penniston, and Ágnes Enyedi
Intramolecular Interactions of the Regulatory Region with the Catalytic Core in the Plasma Membrane Calcium Pump
J. Biol. Chem. 2003 278: 35798-35804. First Published on June 26, 2003; doi:10.1074/jbc.M305794200 [Abstract] [Full Text] [PDF]  

Irina Y. Dobrosotskaya, Joseph L. Goldstein, Michael S. Brown, and Robert B. Rawson
Reconstitution of Sterol-regulated Endoplasmic Reticulum-to-Golgi Transport of SREBP-2 in Insect Cells by Co-expression of Mammalian SCAP and Insigs
J. Biol. Chem. 2003 278: 35837-35843. First Published on July 3, 2003; doi:10.1074/jbc.M306476200 [Abstract] [Full Text] [PDF]  

Alicia Llorente, Silje U. Lauvrak, Bo van Deurs, and Kirsten Sandvig
Induction of Direct Endosome to Endoplasmic Reticulum Transport in Chinese Hamster Ovary (CHO) Cells (LdlF) with a Temperature-sensitive Defect in {epsilon}-Coatomer Protein ({epsilon}-COP)
J. Biol. Chem. 2003 278: 35850-35855. First Published on July 7, 2003; doi:10.1074/jbc.M303425200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Patrick J. M. Murphy, Yoshihiro Morishima, Haifeng Chen, Mario D. Galigniana, John F. Mansfield, S. Stoney Simons, Jr., and William B. Pratt
Visualization and Mechanism of Assembly of a Glucocorticoid Receptor·Hsp70 Complex That Is Primed for Subsequent Hsp90-dependent Opening of the Steroid Binding Cleft
J. Biol. Chem. 2003 278: 34764-34773. First Published on June 13, 2003; doi:10.1074/jbc.M304469200 [Abstract] [Full Text] [PDF]  

Jeremy P. E. Spencer, Catherine Rice-Evans, and Robert J. Williams
Modulation of Pro-survival Akt/Protein Kinase B and ERK1/2 Signaling Cascades by Quercetin and Its in Vivo Metabolites Underlie Their Action on Neuronal Viability
J. Biol. Chem. 2003 278: 34783-34793. First Published on June 24, 2003; doi:10.1074/jbc.M305063200 [Abstract] [Full Text] [PDF]  

Isaac Goncalves, Sascha C. Hughan, Simone M. Schoenwaelder, Cindy L. Yap, Yuping Yuan, and Shaun P. Jackson
Integrin {alpha}IIb{beta}3-dependent Calcium Signals Regulate Platelet-Fibrinogen Interactions under Flow: INVOLVEMENT OF PHOSPHOLIPASE C{gamma}2
J. Biol. Chem. 2003 278: 34812-34822. First Published on June 27, 2003; doi:10.1074/jbc.M306504200 [Abstract] [Full Text] [PDF]  

Narkunaraja Shanmugam, Young Sook Kim, Linda Lanting, and Rama Natarajan
Regulation of Cyclooxygenase-2 Expression in Monocytes by Ligation of the Receptor for Advanced Glycation End Products
J. Biol. Chem. 2003 278: 34834-34844. First Published on June 30, 2003; doi:10.1074/jbc.M302828200 [Abstract] [Full Text] [PDF]  

Jaewon Han, David M. Rose, Darren G. Woodside, Lawrence E. Goldfinger, and Mark H. Ginsberg
Integrin {alpha}4{beta}1-dependent T Cell Migration Requires Both Phosphorylation and Dephosphorylation of the {alpha}4 Cytoplasmic Domain to Regulate the Reversible Binding of Paxillin
J. Biol. Chem. 2003 278: 34845-34853. First Published on June 30, 2003; doi:10.1074/jbc.M304691200 [Abstract] [Full Text] [PDF]  

Tomokazu Ito, Hideki Okazawa, Koji Maruyama, Kyoko Tomizawa, Sei-ichiro Motegi, Hiroshi Ohnishi, Hiroyuki Kuwano, Atsushi Kosugi, and Takashi Matozaki
Interaction of SAP-1, a Transmembrane-type Protein-tyrosine Phosphatase, with the Tyrosine Kinase Lck: ROLES IN REGULATION OF T CELL FUNCTION
J. Biol. Chem. 2003 278: 34854-34863. First Published on July 1, 2003; doi:10.1074/jbc.M300648200 [Abstract] [Full Text] [PDF]  

Yanjun Ma and Linda M. Hendershot
Delineation of a Negative Feedback Regulatory Loop That Controls Protein Translation during Endoplasmic Reticulum Stress
J. Biol. Chem. 2003 278: 34864-34873. First Published on July 1, 2003; doi:10.1074/jbc.M301107200 [Abstract] [Full Text] [PDF]  

Kyoung Seob Song, Je-Kyung Seong, Kwang Chul Chung, Won-Jae Lee, Chang-Hoon Kim, Kyou Nam Cho, Chi-Dug Kang, Ja Seok Koo, and Joo-Heon Yoon
Induction of MUC8 Gene Expression by Interleukin-1{beta} Is Mediated by a Sequential ERK MAPK/RSK1/CREB Cascade Pathway in Human Airway Epithelial Cells
J. Biol. Chem. 2003 278: 34890-34896. First Published on July 3, 2003; doi:10.1074/jbc.M303911200 [Abstract] [Full Text] [PDF]  

Christopher Belham, Joan Roig, Jennifer A. Caldwell, Yumi Aoyama, Bruce E. Kemp, Michael Comb, and Joseph Avruch
A Mitotic Cascade of NIMA Family Kinases: Nercc1/Nek9 ACTIVATES THE Nek6 AND Nek7 KINASES
J. Biol. Chem. 2003 278: 34897-34909. First Published on July 2, 2003; doi:10.1074/jbc.M303663200 [Abstract] [Full Text] [PDF]  

Julie L. Hanson, Vasiliki Anest, Julie Reuther-Madrid, and Albert S. Baldwin
Oncoprotein Suppression of Tumor Necrosis Factor-induced NF{kappa}B Activation Is Independent of Raf-controlled Pathways
J. Biol. Chem. 2003 278: 34910-34917. First Published on July 8, 2003; doi:10.1074/jbc.M304189200 [Abstract] [Full Text] [PDF]  

Michelle A. LaFevre-Bernt and Lisa M. Ellerby
Kennedy's Disease: PHOSPHORYLATION OF THE POLYGLUTAMINE-EXPANDED FORM OF ANDROGEN RECEPTOR REGULATES ITS CLEVAGE BY CASPASE-3 AND ENHANCES CELL DEATH
J. Biol. Chem. 2003 278: 34918-34924. First Published on June 24, 2003; doi:10.1074/jbc.M302841200 [Abstract] [Full Text] [PDF]  

Wayne P. Kelley, Andrew M. Wolters, Jon T. Sack, Rebecca A. Jockusch, John C. Jurchen, Evan R. Williams, Jonathan V. Sweedler, and William F. Gilly
Characterization of a Novel Gastropod Toxin (6-Bromo-2-mercaptotryptamine) That Inhibits Shaker K Channel Activity
J. Biol. Chem. 2003 278: 34934-34942. First Published on June 18, 2003; doi:10.1074/jbc.M301271200 [Abstract] [Full Text] [PDF]  

Mee-Kyung Cha, Seung-Keun Hong, Young-Mee Oh, and Il-Han Kim
The Protein Interaction of Saccharomyces cerevisiae Cytoplasmic Thiol Peroxidase II with SFH2p and Its in Vivo Function
J. Biol. Chem. 2003 278: 34952-34958. First Published on June 24, 2003; doi:10.1074/jbc.M301819200 [Abstract] [Full Text] [PDF]  

Martin J. Cann, Arne Hammer, Jie Zhou, and Tobias Kanacher
A Defined Subset of Adenylyl Cyclases Is Regulated by Bicarbonate Ion
J. Biol. Chem. 2003 278: 35033-35038. First Published on June 26, 2003; doi:10.1074/jbc.M303025200 [Abstract] [Full Text] [PDF] Supplemental Data  

Atsushi Konishi and Bradford C. Berk
Epidermal Growth Factor Receptor Transactivation Is Regulated by Glucose in Vascular Smooth Muscle Cells
J. Biol. Chem. 2003 278: 35049-35056. First Published on June 26, 2003; doi:10.1074/jbc.M304913200 [Abstract] [Full Text] [PDF]  

Michaela Havlickova, Jaroslav Blahos, Isabelle Brabet, Jianfeng Liu, Bohdana Hruskova, Laurent Prézeau, and Jean-Philippe Pin
The Second Intracellular Loop of Metabotropic Glutamate Receptors Recognizes C Termini of G-protein {alpha}-Subunits
J. Biol. Chem. 2003 278: 35063-35070. First Published on June 26, 2003; doi:10.1074/jbc.M306555200 [Abstract] [Full Text] [PDF]  

Marius P. Sumandea, W. Glen Pyle, Tomoyoshi Kobayashi, Pieter P. de Tombe, and R. John Solaro
Identification of a Functionally Critical Protein Kinase C Phosphorylation Residue of Cardiac Troponin T
J. Biol. Chem. 2003 278: 35135-35144. First Published on June 28, 2003; doi:10.1074/jbc.M306325200 [Abstract] [Full Text] [PDF]  

Marianne Høy, Per-Olof Berggren, and Jesper Gromada
Involvement of Protein Kinase C-{epsilon} in Inositol Hexakisphosphate-induced Exocytosis in Mouse Pancreatic {beta}-Cells
J. Biol. Chem. 2003 278: 35168-35171. First Published on July 1, 2003; doi:10.1074/jbc.M303927200 [Abstract] [Full Text] [PDF]  

Patricia A. Ladd, Liping Du, Jorge H. Capdevila, Raymond Mernaugh, and Diane S. Keeney
Epoxyeicosatrienoic Acids Activate Transglutaminases in Situ and Induce Cornification of Epidermal Keratinocytes
J. Biol. Chem. 2003 278: 35184-35192. First Published on July 2, 2003; doi:10.1074/jbc.M301666200 [Abstract] [Full Text] [PDF]  

Christine Cartier, Bénédicte Hemonnot, Bernard Gay, Martine Bardy, Céline Sanchiz, Christian Devaux, and Laurence Briant
Active cAMP-dependent Protein Kinase Incorporated within Highly Purified HIV-1 Particles Is Required for Viral Infectivity and Interacts with Viral Capsid Protein
J. Biol. Chem. 2003 278: 35211-35219. First Published on July 3, 2003; doi:10.1074/jbc.M301257200 [Abstract] [Full Text] [PDF]  

Jose A. Tapia, Luis J. García-Marin, and Robert T. Jensen
Cholecystokinin-stimulated Protein Kinase C-{delta} Kinase Activation, Tyrosine Phosphorylation, and Translocation Are Mediated by Src Tyrosine Kinases in Pancreatic Acinar Cells
J. Biol. Chem. 2003 278: 35220-35230. First Published on July 3, 2003; doi:10.1074/jbc.M303119200 [Abstract] [Full Text] [PDF]  

Margaret M. Chou, Jeffrey M. Masuda-Robens, and Meryl L. Gupta
Cdc42 Promotes G1 Progression through p70 S6 Kinase-mediated Induction of Cyclin E Expression
J. Biol. Chem. 2003 278: 35241-35247. First Published on July 3, 2003; doi:10.1074/jbc.M305246200 [Abstract] [Full Text] [PDF]  

Kyu-Jin Park, Richard B. Gaynor, and Youn Tae Kwak
Heat Shock Protein 27 Association with the I{kappa}B Kinase Complex Regulates Tumor Necrosis Factor {alpha}-induced NF-{kappa}B Activation
J. Biol. Chem. 2003 278: 35272-35278. First Published on June 25, 2003; doi:10.1074/jbc.M305095200 [Abstract] [Full Text] [PDF]  

Jeffery M. Klco, Tracey B. Lassere, and Thomas J. Baranski
C5a Receptor Oligomerization: I. DISULFIDE TRAPPING REVEALS OLIGOMERS AND POTENTIAL CONTACT SURFACES IN A G PROTEIN-COUPLED RECEPTOR
J. Biol. Chem. 2003 278: 35345-35353. First Published on June 30, 2003; doi:10.1074/jbc.M305606200 [Abstract] [Full Text] [PDF]  

Desiree H. Floyd, Adi Geva, Stephen P. Bruinsma, Mark C. Overton, Kendall J. Blumer, and Thomas J. Baranski
C5a Receptor Oligomerization: II. FLUORESCENCE RESONANCE ENERGY TRANSFER STUDIES OF A HUMAN G PROTEIN-COUPLED RECEPTOR EXPRESSED IN YEAST
J. Biol. Chem. 2003 278: 35354-35361. First Published on June 30, 2003; doi:10.1074/jbc.M305607200 [Abstract] [Full Text] [PDF]  

Candace M. Coyle, Mrinalini Puranik, Hwan Youn, Steen Brøndsted Nielsen, Robert D. Williams, Robert L. Kerby, Gary P. Roberts, and Thomas G. Spiro
Activation Mechanism of the CO Sensor CooA: MUTATIONAL AND RESONANCE RAMAN SPECTROSCOPIC STUDIES
J. Biol. Chem. 2003 278: 35384-35393. First Published on June 9, 2003; doi:10.1074/jbc.M301000200 [Abstract] [Full Text] [PDF]  

Anne E. Christensen, Frode Selheim, Johan de Rooij, Sarah Dremier, Frank Schwede, Khanh K. Dao, Aurora Martinez, Carine Maenhaut, Johannes L. Bos, H.-G. Genieser, and Stein O. Døskeland
cAMP Analog Mapping of Epac1 and cAMP Kinase: DISCRIMINATING ANALOGS DEMONSTRATE THAT Epac AND cAMP KINASE ACT SYNERGISTICALLY TO PROMOTE PC-12 CELL NEURITE EXTENSION
J. Biol. Chem. 2003 278: 35394-35402. First Published on June 20, 2003; doi:10.1074/jbc.M302179200 [Abstract] [Full Text] [PDF]  

Antonio Rapacciuolo, Shayela Suvarna, Liza Barki-Harrington, Louis M. Luttrell, Mei Cong, Robert J. Lefkowitz, and Howard A. Rockman
Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates {beta}-1 Adrenergic Receptor Endocytosis through Different Pathways
J. Biol. Chem. 2003 278: 35403-35411. First Published on June 23, 2003; doi:10.1074/jbc.M305675200 [Abstract] [Full Text] [PDF] Supplemental Data  

Li Yin, Yongqing Li, Jian Ren, Hiroaki Kuwahara, and Donald Kufe
Human MUC1 Carcinoma Antigen Regulates Intracellular Oxidant Levels and the Apoptotic Response to Oxidative Stress
J. Biol. Chem. 2003 278: 35458-35464. First Published on June 25, 2003; doi:10.1074/jbc.M301987200 [Abstract] [Full Text] [PDF]  

Lieve Verlinden, Annemieke Verstuyf, Christel Verboven, Guy Eelen, Camiel De Ranter, Ling-Jie Gao, Yong-Jun Chen, Ibrahim Murad, Mihwa Choi, Keiko Yamamoto, Sachiko Yamada, Dirk Van Haver, Maurits Vandewalle, Pierre J. De Clercq, and Roger Bouillon
Previtamin D3 with a trans-Fused Decalin CD-ring Has Pronounced Genomic Activity
J. Biol. Chem. 2003 278: 35476-35482. First Published on June 26, 2003; doi:10.1074/jbc.M302045200 [Abstract] [Full Text] [PDF]  

Xianhe Bai, Francesca Cerimele, Masuko Ushio-Fukai, Muhammad Waqas, Paul M. Campbell, Baskaran Govindarajan, Channing J. Der, Traci Battle, David A. Frank, Keqiang Ye, Emma Murad, Wolfgang Dubiel, Gerald Soff, and Jack L. Arbiser
Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo
J. Biol. Chem. 2003 278: 35501-35507. First Published on June 19, 2003; doi:10.1074/jbc.M302967200 [Abstract] [Full Text] [PDF]  

Lior Zilberberg, Svetlana Shinkaruk, Olivier Lequin, Benoit Rousseau, Martin Hagedorn, Francesco Costa, Dario Caronzolo, Maurice Balke, Xavier Canron, Odile Convert, Georges Laïn, Karine Gionnet, Mario Gonçalvès, Mireille Bayle, Lorenzo Bello, Gerard Chassaing, Gérard Deleris, and Andreas Bikfalvi
Structure and Inhibitory Effects on Angiogenesis and Tumor Development of a New Vascular Endothelial Growth Inhibitor
J. Biol. Chem. 2003 278: 35564-35573. First Published on July 1, 2003; doi:10.1074/jbc.M304435200 [Abstract] [Full Text] [PDF] Supplemental Data  

Angel Ciprés, Silvia Carrasco, Ernesto Merino, Ernesto Díaz, U. Murali Krishna, John R. Falck, Carlos Martínez-A, and Isabel Mérida
Regulation of Diacylglycerol Kinase {alpha} by Phosphoinositide 3-Kinase Lipid Products
J. Biol. Chem. 2003 278: 35629-35635. First Published on June 27, 2003; doi:10.1074/jbc.M305635200 [Abstract] [Full Text] [PDF]  

Yama A. Abassi, Marko Rehn, Niklas Ekman, Kari Alitalo, and Kristiina Vuori
p130Cas Couples the Tyrosine Kinase Bmx/Etk with Regulation of the Actin Cytoskeleton and Cell Migration
J. Biol. Chem. 2003 278: 35636-35643. First Published on June 28, 2003; doi:10.1074/jbc.M306438200 [Abstract] [Full Text] [PDF]  

Ming Zhang, Gilda M. Kalinec, Raul Urrutia, Daniel D. Billadeau, and Federico Kalinec
ROCK-dependent and ROCK-independent Control of Cochlear Outer Hair Cell Electromotility
J. Biol. Chem. 2003 278: 35644-35650. First Published on July 1, 2003; doi:10.1074/jbc.M301668200 [Abstract] [Full Text] [PDF]  

Christopher M. Tan, Hilary Highfield Nickols, and Lee E. Limbird
Appropriate Polarization following Pharmacological Rescue of V2 Vasopressin Receptors Encoded by X-linked Nephrogenic Diabetes Insipidus Alleles Involves a Conformation of the Receptor That Also Attains Mature Glycosylation
J. Biol. Chem. 2003 278: 35678-35686. First Published on June 24, 2003; doi:10.1074/jbc.M301888200 [Abstract] [Full Text] [PDF]  

Annamaria Biroccio, Sarah Amodei, Anna Antonelli, Barbara Benassi, and Gabriella Zupi
Inhibition of c-Myc Oncoprotein Limits the Growth of Human Melanoma Cells by Inducing Cellular Crisis
J. Biol. Chem. 2003 278: 35693-35701. First Published on June 24, 2003; doi:10.1074/jbc.M304597200 [Abstract] [Full Text] [PDF]  

Bing-Sheng Li, Wu Ma, Howard Jaffe, Yali Zheng, Satoru Takahashi, Lei Zhang, Ashok B. Kulkarni, and Harish C. Pant
Cyclin-dependent Kinase-5 Is Involved in Neuregulin-dependent Activation of Phosphatidylinositol 3-Kinase and Akt Activity Mediating Neuronal Survival
J. Biol. Chem. 2003 278: 35702-35709. First Published on June 24, 2003; doi:10.1074/jbc.M302004200 [Abstract] [Full Text] [PDF]  

Latha P. Ganesan, Huiqing Fang, Clay B. Marsh, and Susheela Tridandapani
The Protein-tyrosine Phosphatase SHP-1 Associates with the Phosphorylated Immunoreceptor Tyrosine-based Activation Motif of Fc{gamma}RIIa to Modulate Signaling Events in Myeloid Cells
J. Biol. Chem. 2003 278: 35710-35717. First Published on June 27, 2003; doi:10.1074/jbc.M305078200 [Abstract] [Full Text] [PDF]  

Junko Hatakeyama, Taduru Sreenath, Yuji Hatakeyama, Tamizchelvi Thyagarajan, Lillian Shum, Carolyn W. Gibson, J. Tim Wright, and Ashok B. Kulkarni
The Receptor Activator of Nuclear Factor-{kappa}B Ligand-mediated Osteoclastogenic Pathway Is Elevated in Amelogenin-null Mice
J. Biol. Chem. 2003 278: 35743-35748. First Published on July 8, 2003; doi:10.1074/jbc.M306284200 [Abstract] [Full Text] [PDF]  

Anuradha Balasubramanian, Ramesh K. Ganju, and Jerome E. Groopman
Hepatitis C Virus and HIV Envelope Proteins Collaboratively Mediate Interleukin-8 Secretion through Activation of p38 MAP Kinase and SHP2 in Hepatocytes
J. Biol. Chem. 2003 278: 35755-35766. First Published on June 24, 2003; doi:10.1074/jbc.M302889200 [Abstract] [Full Text] [PDF]  

Julie A. Cook, Lee Albacker, Avery August, and Andrew J. Henderson
CD28-dependent HIV-1 Transcription Is Associated with Vav, Rac, and NF-{kappa}B Activation
J. Biol. Chem. 2003 278: 35812-35818. First Published on July 3, 2003; doi:10.1074/jbc.M302878200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Kyung-Joo Cho, Hae-Eun Moon, Hadi Moini, Lester Packer, Do-Young Yoon, and An-Sik Chung
{alpha}-Lipoic Acid Inhibits Adipocyte Differentiation by Regulating Pro-adipogenic Transcription Factors via Mitogen-activated Protein Kinase Pathways
J. Biol. Chem. 2003 278: 34823-34833. First Published on June 30, 2003; doi:10.1074/jbc.M210747200 [Abstract] [Full Text] [PDF]  

Charlotte H. Widberg, Nia J. Bryant, Milena Girotti, Shane Rea, and David E. James
Tomosyn Interacts with the t-SNAREs Syntaxin4 and SNAP23 and Plays a Role in Insulin-stimulated GLUT4 Translocation
J. Biol. Chem. 2003 278: 35093-35101. First Published on June 27, 2003; doi:10.1074/jbc.M304261200 [Abstract] [Full Text] [PDF]  

Amere Subbarao Sreedhar, Katalin Mihály, Bálint Pató, Tamás Schnaider, Attila Steták, Katalin Kis-Petik, Judit Fidy, Tibor Simonics, Anna Maráz, and Péter Csermely
Hsp90 Inhibition Accelerates Cell Lysis: ANTI-Hsp90 RIBOZYME REVEALS A COMPLEX MECHANISM OF Hsp90 INHIBITORS INVOLVING BOTH SUPEROXIDE- AND Hsp90-DEPENDENT EVENTS
J. Biol. Chem. 2003 278: 35231-35240. First Published on July 3, 2003; doi:10.1074/jbc.M301371200 [Abstract] [Full Text] [PDF]  

Tatsushi Shingai, Wataru Ikeda, Shigeki Kakunaga, Koji Morimoto, Kyoji Takekuni, Shinsuke Itoh, Keiko Satoh, Masakazu Takeuchi, Toshio Imai, Morito Monden, and Yoshimi Takai
Implications of Nectin-like Molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in Cell-Cell Adhesion and Transmembrane Protein Localization in Epithelial Cells
J. Biol. Chem. 2003 278: 35421-35427. First Published on June 25, 2003; doi:10.1074/jbc.M305387200 [Abstract] [Full Text] [PDF]  

Peter M. Siegel, Weiping Shu, and Joan Massagué
Mad Upregulation and Id2 Repression Accompany Transforming Growth Factor (TGF)-{beta}-mediated Epithelial Cell Growth Suppression
J. Biol. Chem. 2003 278: 35444-35450. First Published on June 24, 2003; doi:10.1074/jbc.M301413200 [Abstract] [Full Text] [PDF]  

Hiroki Toda, Masayuki Tsuji, Ichiro Nakano, Kazuhiro Kobuke, Takeshi Hayashi, Hironori Kasahara, Jun Takahashi, Akira Mizoguchi, Takeshi Houtani, Tetsuo Sugimoto, Nobuo Hashimoto, Theo D. Palmer, Tasuku Honjo, and Kei Tashiro
Stem Cell-derived Neural Stem/Progenitor Cell Supporting Factor Is an Autocrine/Paracrine Survival Factor for Adult Neural Stem/Progenitor Cells
J. Biol. Chem. 2003 278: 35491-35500. First Published on June 27, 2003; doi:10.1074/jbc.M305342200 [Abstract] [Full Text] [PDF]  

Wen-Wei Zhang, Susana Mendez, Anirban Ghosh, Peter Myler, Al Ivens, Joachim Clos, David L. Sacks, and Greg Matlashewski
Comparison of the A2 Gene Locus in Leishmania donovani and Leishmania major and Its Control over Cutaneous Infection
J. Biol. Chem. 2003 278: 35508-35515. First Published on June 26, 2003; doi:10.1074/jbc.M305030200 [Abstract] [Full Text] [PDF]  

Sergey S. Akimov and Alexey M. Belkin
Opposing Roles of Ras/Raf Oncogenes and the MEK1/ERK Signaling Module in Regulation of Expression and Adhesive Function of Surface Transglutaminase
J. Biol. Chem. 2003 278: 35609-35619. First Published on June 27, 2003; doi:10.1074/jbc.M303488200 [Abstract] [Full Text] [PDF] Supplemental Data  

Rihong Zhou, Xinwang Cao, Charles Watson, Yong Miao, Zhen Guo, John G. Forte, and Xuebiao Yao
Characterization of Protein Kinase A-mediated Phosphorylation of Ezrin in Gastric Parietal Cell Activation
J. Biol. Chem. 2003 278: 35651-35659. First Published on July 2, 2003; doi:10.1074/jbc.M303416200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Meenakshi A. Chellaiah, Rajat S. Biswas, Susan R. Rittling, David T. Denhardt, and Keith A. Hruska
Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts.
J. Biol. Chem. 2003 278: 35856. [Full Text] [PDF]  


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