JBC INTERFERin siRNA transfection reagent

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 Table of Contents: Oct 3 2003; 278 (40)   [Index by Author]  [Cover Figure and Caption]
       Minireviews
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Genomics, Proteomics, and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Minireviews:

Shizuo Akira
Toll-like Receptor Signaling
J. Biol. Chem. 2003 278: 38105-38108. First Published on July 30, 2003; doi:10.1074/jbc.R300028200 [Full Text] [PDF]  

Accelerated Publications:

Ok-kyu Song, Xiaorong Wang, Jakob H. Waterborg, and Rolf Sternglanz
An N{alpha}-Acetyltransferase Responsible for Acetylation of the N-terminal Residues of Histones H4 and H2A
J. Biol. Chem. 2003 278: 38109-38112. First Published on August 12, 2003; doi:10.1074/jbc.C300355200 [Abstract] [Full Text] [PDF]  

Eva M. Gonzalez, Maurizio Mongiat, Simon J. Slater, Raffaele Baffa, and Renato V. Iozzo
A Novel Interaction between Perlecan Protein Core and Progranulin: POTENTIAL EFFECTS ON TUMOR GROWTH
J. Biol. Chem. 2003 278: 38113-38116. First Published on August 4, 2003; doi:10.1074/jbc.C300310200 [Abstract] [Full Text] [PDF]  

Jieya Shao, Thomas Prince, Steven D. Hartson, and Robert L. Matts
Phosphorylation of Serine 13 Is Required for the Proper Function of the Hsp90 Co-chaperone, Cdc37
J. Biol. Chem. 2003 278: 38117-38120. First Published on August 20, 2003; doi:10.1074/jbc.C300330200 [Abstract] [Full Text] [PDF]  

Seiki Hirano, Yohei Tominaga, Akimasa Ichinoe, Yasuhiro Ushijima, Daisuke Tsuchimoto, Yoko Honda-Ohnishi, Toshio Ohtsubo, Kunihiko Sakumi, and Yusaku Nakabeppu
Mutator Phenotype of MUTYH-null Mouse Embryonic Stem Cells
J. Biol. Chem. 2003 278: 38121-38124. First Published on August 13, 2003; doi:10.1074/jbc.C300316200 [Abstract] [Full Text] [PDF]  

DNA: Replication, Repair, and Recombination:

Yan Chen, Mini Balakrishnan, Bernard P. Roques, and Robert A. Bambara
Steps of the Acceptor Invasion Mechanism for HIV-1 Minus Strand Strong Stop Transfer
J. Biol. Chem. 2003 278: 38368-38375. First Published on July 22, 2003; doi:10.1074/jbc.M305700200 [Abstract] [Full Text] [PDF]  

Gil Blander, Rita Machado de Oliveira, Caitlin M. Conboy, Marcia Haigis, and Leonard Guarente
Superoxide Dismutase 1 Knock-down Induces Senescence in Human Fibroblasts
J. Biol. Chem. 2003 278: 38966-38969. First Published on July 18, 2003; doi:10.1074/jbc.M307146200 [Abstract] [Full Text] [PDF]  

Erin N. Worthington, I. Halil Kavakli, Gloria Berrocal-Tito, Bruce E. Bondo, and Aziz Sancar
Purification and Characterization of Three Members of the Photolyase/Cryptochrome Family Blue-light Photoreceptors from Vibrio cholerae
J. Biol. Chem. 2003 278: 39143-39154. First Published on July 22, 2003; doi:10.1074/jbc.M305792200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Vicky Y. Lin, Eileen M. Resnick, and Margaret A. Shupnik
Truncated Estrogen Receptor Product-1 Stimulates Estrogen Receptor {alpha} Transcriptional Activity by Titration of Repressor Proteins
J. Biol. Chem. 2003 278: 38125-38131. First Published on July 23, 2003; doi:10.1074/jbc.M303882200 [Abstract] [Full Text] [PDF]  

Mingli Yang, Takahiko Ito, and W. Stratford May
A Novel Role for RAX, the Cellular Activator of PKR, in Synergistically Stimulating SV40 Large T Antigen-dependent Gene Expression
J. Biol. Chem. 2003 278: 38325-38332. First Published on July 21, 2003; doi:10.1074/jbc.M303420200 [Abstract] [Full Text] [PDF]  

Yali E. Friedman and Mark R. O'Brian
A Novel DNA-binding Site for the Ferric Uptake Regulator (Fur) Protein from Bradyrhizobium japonicum
J. Biol. Chem. 2003 278: 38395-38401. First Published on July 23, 2003; doi:10.1074/jbc.M306710200 [Abstract] [Full Text] [PDF]  

YuanXiang Pan, Hong Chen, Fai Siu, and Michael S. Kilberg
Amino Acid Deprivation and Endoplasmic Reticulum Stress Induce Expression of Multiple Activating Transcription Factor-3 mRNA Species That, When Overexpressed in HepG2 Cells, Modulate Transcription by the Human Asparagine Synthetase Promoter
J. Biol. Chem. 2003 278: 38402-38412. First Published on July 24, 2003; doi:10.1074/jbc.M304574200 [Abstract] [Full Text] [PDF]  

Chang-Hoon Kim, Wen C. Xiong, and Lin Mei
Regulation of MuSK Expression by a Novel Signaling Pathway
J. Biol. Chem. 2003 278: 38522-38527. First Published on July 28, 2003; doi:10.1074/jbc.M305058200 [Abstract] [Full Text] [PDF]  

Dongsheng Chen, Marie J. Lucey, Fladia Phoenix, Jorge Lopez-Garcia, Stephen M. Hart, Régine Losson, Lakjaya Buluwela, R. Charles Coombes, Pierre Chambon, Primo Schär, and Simak Ali
T:G Mismatch-specific Thymine-DNA Glycosylase Potentiates Transcription of Estrogen-regulated Genes through Direct Interaction with Estrogen Receptor {alpha}
J. Biol. Chem. 2003 278: 38586-38592. First Published on July 21, 2003; doi:10.1074/jbc.M304286200 [Abstract] [Full Text] [PDF]  

Mary Elizabeth Gardocki and John M. Lopes
Expression of the Yeast PIS1 Gene Requires Multiple Regulatory Elements Including a Rox1p Binding Site
J. Biol. Chem. 2003 278: 38646-38652. First Published on July 30, 2003; doi:10.1074/jbc.M305251200 [Abstract] [Full Text] [PDF]  

Robert J. Kelm, Jr., Shu-Xia Wang, John A. Polikandriotis, and Arthur R. Strauch
Structure/Function Analysis of Mouse Pur{beta}, a Single-stranded DNA-binding Repressor of Vascular Smooth Muscle {alpha}-Actin Gene Transcription
J. Biol. Chem. 2003 278: 38749-38757. First Published on July 21, 2003; doi:10.1074/jbc.M306163200 [Abstract] [Full Text] [PDF]  

Frank J. Kaiser, Tarik Möröy, Glenn T. G. Chang, Bernhard Horsthemke, and Hermann-Josef Lüdecke
The RING Finger Protein RNF4, a Co-regulator of Transcription, Interacts with the TRPS1 Transcription Factor
J. Biol. Chem. 2003 278: 38780-38785. First Published on July 28, 2003; doi:10.1074/jbc.M306259200 [Abstract] [Full Text] [PDF]  

Ana G. Rondón, Sonia Jimeno, María García-Rubio, and Andrés Aguilera
Molecular Evidence That the Eukaryotic THO/TREX Complex Is Required for Efficient Transcription Elongation
J. Biol. Chem. 2003 278: 39037-39043. First Published on July 18, 2003; doi:10.1074/jbc.M305718200 [Abstract] [Full Text] [PDF]  

Dorota A. Kwasnicka, Agnieszka Krakowiak, Colin Thacker, Charles Brenner, and Steven R. Vincent
Coordinate Expression of NADPH-dependent Flavin Reductase, Fre-1, and Hint-related 7meGMP-directed Hydrolase, DCS-1
J. Biol. Chem. 2003 278: 39051-39058. First Published on July 18, 2003; doi:10.1074/jbc.M306355200 [Abstract] [Full Text] [PDF] Supplemental Data  

Seongwoo Hwang, Natarajan Tamilarasu, Karen Kibler, Hong Cao, Akbar Ali, Yueh-Hsin Ping, Kuan-Teh Jeang, and Tariq M. Rana
Discovery of a Small Molecule Tat-trans-Activation-responsive RNA Antagonist That Potently Inhibits Human Immunodeficiency Virus-1 Replication
J. Biol. Chem. 2003 278: 39092-39103. First Published on July 11, 2003; doi:10.1074/jbc.M301749200 [Abstract] [Full Text] [PDF]  

Emma De Fabiani, Nico Mitro, Federica Gilardi, Donatella Caruso, Giovanni Galli, and Maurizio Crestani
Coordinated Control of Cholesterol Catabolism to Bile Acids and of Gluconeogenesis via a Novel Mechanism of Transcription Regulation Linked to the Fasted-to-fed Cycle
J. Biol. Chem. 2003 278: 39124-39132. First Published on July 15, 2003; doi:10.1074/jbc.M305079200 [Abstract] [Full Text] [PDF]  

Mátyás Czipri, Jeffrey M. Otto, Gabriella Cs-Szabó, Rajesh V. Kamath, Csaba Vermes, Gábor Firneisz, Kevin J. Kolman, Hideto Watanabe, Yefu Li, Peter J. Roughley, Yoshihiko Yamada, Björn R. Olsen, and Tibor T. Glant
Genetic Rescue of Chondrodysplasia and the Perinatal Lethal Effect of Cartilage Link Protein Deficiency
J. Biol. Chem. 2003 278: 39214-39223. First Published on May 5, 2003; doi:10.1074/jbc.M303329200 [Abstract] [Full Text] [PDF]  

Elena Longobardi and Francesco Blasi
Overexpression of PREP-1 in F9 Teratocarcinoma Cells Leads to a Functionally Relevant Increase of PBX-2 by Preventing Its Degradation
J. Biol. Chem. 2003 278: 39235-39241. First Published on July 18, 2003; doi:10.1074/jbc.M304704200 [Abstract] [Full Text] [PDF]  

RNA: Structure, Metabolism, and Catalysis:

Gusti M. Zeiner, Nancy R. Sturm, and David A. Campbell
The Leishmania tarentolae Spliced Leader Contains Determinants for Association with Polysomes
J. Biol. Chem. 2003 278: 38269-38275. First Published on July 22, 2003; doi:10.1074/jbc.M304295200 [Abstract] [Full Text] [PDF]  

Nao Hosoda, Tetsuo Kobayashi, Naoyuki Uchida, Yuji Funakoshi, Yoshiko Kikuchi, Shinichi Hoshino, and Toshiaki Katada
Translation Termination Factor eRF3 Mediates mRNA Decay through the Regulation of Deadenylation
J. Biol. Chem. 2003 278: 38287-38291. First Published on August 15, 2003; doi:10.1074/jbc.C300300200 [Abstract] [Full Text] [PDF] Supplemental Data  

Hushan Yang, Juhua Zhou, Robert L. Ochs, Dale Henning, Runyan Jin, and Benigno C. Valdez
Down-regulation of RNA Helicase II/Gu Results in the Depletion of 18 and 28 S rRNAs in Xenopus Oocyte
J. Biol. Chem. 2003 278: 38847-38859. First Published on July 8, 2003; doi:10.1074/jbc.M302258200 [Abstract] [Full Text] [PDF]  

Tadeusz Kulinski, Mikolaj Olejniczak, Hendrik Huthoff, Lukasz Bielecki, Katarzyna Pachulska-Wieczorek, Atze T. Das, Ben Berkhout, and Ryszard W. Adamiak
The Apical Loop of the HIV-1 TAR RNA Hairpin Is Stabilized by a Cross-loop Base Pair
J. Biol. Chem. 2003 278: 38892-38901. First Published on July 25, 2003; doi:10.1074/jbc.M301939200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Jack M. Webster, Swati Tiwari, Allan M. Weissman, and Richard J. H. Wojcikiewicz
Inositol 1,4,5-Trisphosphate Receptor Ubiquitination Is Mediated by Mammalian Ubc7, a Component of the Endoplasmic Reticulum-associated Degradation Pathway, and Is Inhibited by Chelation of Intracellular Zn2+
J. Biol. Chem. 2003 278: 38238-38246. First Published on July 17, 2003; doi:10.1074/jbc.M305600200 [Abstract] [Full Text] [PDF]  

Véronique Noé, Simon MacKenzie, and Carlos J. Ciudad
An Intron Is Required for Dihydrofolate Reductase Protein Stability
J. Biol. Chem. 2003 278: 38292-38300. First Published on July 15, 2003; doi:10.1074/jbc.M212746200 [Abstract] [Full Text] [PDF]  

Petra de Graaf, Natalie A. Little, Yolande F. M. Ramos, Erik Meulmeester, Stef J. F. Letteboer, and Aart G. Jochemsen
Hdmx Protein Stability Is Regulated by the Ubiquitin Ligase Activity of Mdm2
J. Biol. Chem. 2003 278: 38315-38324. First Published on July 21, 2003; doi:10.1074/jbc.M213034200 [Abstract] [Full Text] [PDF]  

Laurent Loiseau, Sandrine Ollagnier-de-Choudens, Laurence Nachin, Marc Fontecave, and Frédéric Barras
Biogenesis of Fe-S Cluster by the Bacterial Suf System: SufS AND SufE FORM A NEW TYPE OF CYSTEINE DESULFURASE
J. Biol. Chem. 2003 278: 38352-38359. First Published on July 21, 2003; doi:10.1074/jbc.M305953200 [Abstract] [Full Text] [PDF]  

Sean M. Culbertson, Ekaterina I. Vassilenko, Lisa D. Morrison, and Keith. U. Ingold
Paradoxical Impact of Antioxidants on Post-Amadori Glycoxidation: COUNTERINTUITIVE INCREASE IN THE YIELDS OF PENTOSIDINE AND N{epsilon}-CARBOXYMETHYLLYSINE USING A NOVEL MULTIFUNCTIONAL PYRIDOXAMINE DERIVATIVE
J. Biol. Chem. 2003 278: 38384-38394. First Published on July 23, 2003; doi:10.1074/jbc.M305099200 [Abstract] [Full Text] [PDF] Data Supplement  

Yuko Miura-Shimura, Lei Duan, Navin L. Rao, Alagarsamy L. Reddi, Hideki Shimura, Rob Rottapel, Brain J. Druker, Alexander Tsygankov, Vimla Band, and Hamid Band
Cbl-mediated Ubiquitinylation and Negative Regulation of Vav
J. Biol. Chem. 2003 278: 38495-38504. First Published on July 24, 2003; doi:10.1074/jbc.M305656200 [Abstract] [Full Text] [PDF]  

Patricia Rodriguez, Moninder S. Bhogal, and John Colyer
Stoichiometric Phosphorylation of Cardiac Ryanodine Receptor on Serine 2809 by Calmodulin-dependent Kinase II and Protein Kinase A
J. Biol. Chem. 2003 278: 38593-38600. First Published ; doi:10.1074/jbc.C301180200 [Abstract] [Full Text] [PDF]  

Genomics, Proteomics, and Bioinformatics:

Rui-Dong Duan, Tomas Bergman, Ning Xu, Jun Wu, Yajun Cheng, Jianxin Duan, Sven Nelander, Carina Palmberg, and Åke Nilsson
Identification of Human Intestinal Alkaline Sphingomyelinase as a Novel Ecto-enzyme Related to the Nucleotide Phosphodiesterase Family
J. Biol. Chem. 2003 278: 38528-38536. First Published on July 28, 2003; doi:10.1074/jbc.M305437200 [Abstract] [Full Text] [PDF]  

Teresa C. Santiago and Choukri Ben Mamoun
Genome Expression Analysis in Yeast Reveals Novel Transcriptional Regulation by Inositol and Choline and New Regulatory Functions for Opi1p, Ino2p, and Ino4p
J. Biol. Chem. 2003 278: 38723-38730. First Published on July 18, 2003; doi:10.1074/jbc.M303008200 [Abstract] [Full Text] [PDF]  

Sajida Hassan, Bao Duong, Kwang-Soo Kim, and Michael F. Miles
Pharmacogenomic Analysis of Mechanisms Mediating Ethanol Regulation of Dopamine {beta}-Hydroxylase
J. Biol. Chem. 2003 278: 38860-38869. First Published on July 3, 2003; doi:10.1074/jbc.M305040200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Sönke Tobaben, Frederique Varoqueaux, Nils Brose, Bernd Stahl, and Guido Meyer
A Brain-specific Isoform of Small Glutamine-rich Tetratricopeptide Repeat-containing Protein Binds to Hsc70 and the Cysteine String Protein
J. Biol. Chem. 2003 278: 38376-38383. First Published on July 23, 2003; doi:10.1074/jbc.M301558200 [Abstract] [Full Text] [PDF]  

Kausik Chattopadhyay and Kalyan K. Banerjee
Unfolding of Vibrio cholerae Hemolysin Induces Oligomerization of the Toxin Monomer
J. Biol. Chem. 2003 278: 38470-38475. First Published on July 23, 2003; doi:10.1074/jbc.M305965200 [Abstract] [Full Text] [PDF]  

Scott Allen, Hui Lu, David Thornton, and Kostas Tokatlidis
Juxtaposition of the Two Distal CX3C Motifs via Intrachain Disulfide Bonding Is Essential for the Folding of Tim10
J. Biol. Chem. 2003 278: 38505-38513. First Published on July 25, 2003; doi:10.1074/jbc.M306027200 [Abstract] [Full Text] [PDF]  

Orsolya Barabás, Michaela Rumlová, Anna Erdei, Veronika Pongrácz, Iva Pichová, and Beáta G. Vértessy
dUTPase and Nucleocapsid Polypeptides of the Mason-Pfizer Monkey Virus Form a Fusion Protein in the Virion with Homotrimeric Organization and Low Catalytic Efficiency
J. Biol. Chem. 2003 278: 38803-38812. First Published on July 16, 2003; doi:10.1074/jbc.M306967200 [Abstract] [Full Text] [PDF]  

Mathias Färnegårdh, Tomas Bonn, Sherry Sun, Jan Ljunggren, Harri Ahola, Anna Wilhelmsson, Jan-Åke Gustafsson, and Mats Carlquist
The Three-dimensional Structure of the Liver X Receptor {beta} Reveals a Flexible Ligand-binding Pocket That Can Accommodate Fundamentally Different Ligands
J. Biol. Chem. 2003 278: 38821-38828. First Published on June 20, 2003; doi:10.1074/jbc.M304842200 [Abstract] [Full Text] [PDF]  

Laura Ragona, Federico Fogolari, Maddalena Catalano, Raffaella Ugolini, Lucia Zetta, and Henriette Molinari
EF Loop Conformational Change Triggers Ligand Binding in {beta}-Lactoglobulins
J. Biol. Chem. 2003 278: 38840-38846. First Published on July 11, 2003; doi:10.1074/jbc.M306269200 [Abstract] [Full Text] [PDF]  

Srinivas Honnappa, Brian Cutting, Wolfgang Jahnke, Joachim Seelig, and Michel O. Steinmetz
Thermodynamics of the Op18/Stathmin-Tubulin Interaction
J. Biol. Chem. 2003 278: 38926-38934. First Published on July 14, 2003; doi:10.1074/jbc.M305546200 [Abstract] [Full Text] [PDF]  

Jason Baardsnes, Michael J. Kuiper, and Peter L. Davies
Antifreeze Protein Dimer: WHEN TWO ICE-BINDING FACES ARE BETTER THAN ONE
J. Biol. Chem. 2003 278: 38942-38947. First Published on July 17, 2003; doi:10.1074/jbc.M306776200 [Abstract] [Full Text] [PDF]  

Anna Jansson, Jarmo Niemi, Pekka Mäntsälä, and Gunter Schneider
Crystal Structure of Aclacinomycin Methylesterase with Bound Product Analogues: IMPLICATIONS FOR ANTHRACYCLINE RECOGNITION AND MECHANISM
J. Biol. Chem. 2003 278: 39006-39013. First Published on July 23, 2003; doi:10.1074/jbc.M304008200 [Abstract] [Full Text] [PDF]  

Aleksandar Stojanovic, Irene Hwang, Har Gobind Khorana, and John Hwa
Retinitis Pigmentosa Rhodopsin Mutations L125R and A164V Perturb Critical Interhelical Interactions: NEW INSIGHTS THROUGH COMPENSATORY MUTATIONS AND CRYSTAL STRUCTURE ANALYSIS
J. Biol. Chem. 2003 278: 39020-39028. First Published on July 18, 2003; doi:10.1074/jbc.M303625200 [Abstract] [Full Text] [PDF]  

David H. Dyer, Scott Lovell, James B. Thoden, Hazel M. Holden, Ivan Rayment, and Que Lan
The Structural Determination of an Insect Sterol Carrier Protein-2 with a Ligand-bound C16 Fatty Acid at 1.35-Å Resolution
J. Biol. Chem. 2003 278: 39085-39091. First Published on July 10, 2003; doi:10.1074/jbc.M306214200 [Abstract] [Full Text] [PDF]  

Miriam Wingens, Tine Walma, Hugo van Ingen, Catelijne Stortelers, Jeroen E. M. van Leeuwen, Everardus J. J. van Zoelen, and Geerten W. Vuister
Structural Analysis of an Epidermal Growth Factor/Transforming Growth Factor-{alpha} Chimera with Unique ErbB Binding Specificity
J. Biol. Chem. 2003 278: 39114-39123. First Published on July 16, 2003; doi:10.1074/jbc.M305603200 [Abstract] [Full Text] [PDF]  

Yi Ding, Ming-Qun Xu, Inca Ghosh, Xuehui Chen, Sebastien Ferrandon, Guillaume Lesage, and Zihe Rao
Crystal Structure of a Mini-intein Reveals a Conserved Catalytic Module Involved in Side Chain Cyclization of Asparagine during Protein Splicing
J. Biol. Chem. 2003 278: 39133-39142. First Published on July 23, 2003; doi:10.1074/jbc.M306197200 [Abstract] [Full Text] [PDF] Supplemental Data  

Lucia Pappalardo, Ingo G. Janausch, Vinesh Vijayan, Eva Zientz, Jochen Junker, Wolfgang Peti, Markus Zweckstetter, Gottfried Unden, and Christian Griesinger
The NMR Structure of the Sensory Domain of the Membranous Two-component Fumarate Sensor (Histidine Protein Kinase) DcuS of Escherichia coli
J. Biol. Chem. 2003 278: 39185-39188. First Published on August 7, 2003; doi:10.1074/jbc.C300344200 [Abstract] [Full Text] [PDF]  

Stefan Reinelt, Eckhard Hofmann, Tanja Gerharz, Michael Bott, and Dean R. Madden
The Structure of the Periplasmic Ligand-binding Domain of the Sensor Kinase CitA Reveals the First Extracellular PAS Domain
J. Biol. Chem. 2003 278: 39189-39196. First Published on July 16, 2003; doi:10.1074/jbc.M305864200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Mihály Kovács, Fei Wang, Aihua Hu, Yue Zhang, and James R. Sellers
Functional Divergence of Human Cytoplasmic Myosin II: KINETIC CHARACTERIZATION OF THE NON-MUSCLE IIA ISOFORM
J. Biol. Chem. 2003 278: 38132-38140. First Published on July 7, 2003; doi:10.1074/jbc.M305453200 [Abstract] [Full Text] [PDF]  

Thomas Kupke, Pilar Hernández-Acosta, and Francisco A. Culiáñez-Macià
4'-Phosphopantetheine and Coenzyme A Biosynthesis in Plants
J. Biol. Chem. 2003 278: 38229-38237. First Published on July 14, 2003; doi:10.1074/jbc.M306321200 [Abstract] [Full Text] [PDF]  

Horatiu Olteanu and Ruma Banerjee
Redundancy in the Pathway for Redox Regulation of Mammalian Methionine Synthase: REDUCTIVE ACTIVATION BY THE DUAL FLAVOPROTEIN, NOVEL REDUCTASE 1
J. Biol. Chem. 2003 278: 38310-38314. First Published on July 18, 2003; doi:10.1074/jbc.M306282200 [Abstract] [Full Text] [PDF]  

Nenoo Rawal and Michael K. Pangburn
Formation of High Affinity C5 Convertase of the Classical Pathway of Complement
J. Biol. Chem. 2003 278: 38476-38483. First Published on July 23, 2003; doi:10.1074/jbc.M307017200 [Abstract] [Full Text] [PDF]  

Aixiang Jiang and Duanqing Pei
Distinct Roles of Catalytic and Pexin-like Domains in Membrane-type Matrix Metalloproteinase (MMP)-mediated Pro-MMP-2 Activation and Collagenolysis
J. Biol. Chem. 2003 278: 38765-38771. First Published on July 23, 2003; doi:10.1074/jbc.M306618200 [Abstract] [Full Text] [PDF]  

Joseph L. Johnson, Bernadette Cusack, Thomas F. Hughes, Elizabeth H. McCullough, Abdul Fauq, Peteris Romanovskis, Arno F. Spatola, and Terrone L. Rosenberry
Inhibitors Tethered Near the Acetylcholinesterase Active Site Serve as Molecular Rulers of the Peripheral and Acylation Sites
J. Biol. Chem. 2003 278: 38948-38955. First Published on July 8, 2003; doi:10.1074/jbc.M304797200 [Abstract] [Full Text] [PDF]  

Dongtao Ni Li, Stephen P. Matthews, Antony N. Antoniou, Daniela Mazzeo, and Colin Watts
Multistep Autoactivation of Asparaginyl Endopeptidase in Vitro and in Vivo
J. Biol. Chem. 2003 278: 38980-38990. First Published on July 14, 2003; doi:10.1074/jbc.M305930200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Agnès Conjard, Ola Komaty, Hélène Delage, Michelle Boghossian, Mireille Martin, Bernard Ferrier, and Gabriel Baverel
Inhibition of Glutamine Synthetase in the Mouse Kidney: A NOVEL MECHANISM OF ADAPTATION TO METABOLIC ACIDOSIS
J. Biol. Chem. 2003 278: 38159-38166. First Published on July 18, 2003; doi:10.1074/jbc.M302885200 [Abstract] [Full Text] [PDF]  

Nobuhiro Ikezawa, Masaru Tanaka, Masanori Nagayoshi, Raku Shinkyo, Toshiyuki Sakaki, Kuniyo Inouye, and Fumihiko Sato
Molecular Cloning and Characterization of CYP719, a Methylenedioxy Bridge-forming Enzyme That Belongs to a Novel P450 Family, from cultured Coptis japonica Cells
J. Biol. Chem. 2003 278: 38557-38565. First Published on May 5, 2003; doi:10.1074/jbc.M302470200 [Abstract] [Full Text] [PDF]  

Ei Sekoguchi, Norihiro Sato, Akihiro Yasui, Shinji Fukada, Yuji Nimura, Hiroyuki Aburatani, Kyoji Ikeda, and Akira Matsuura
A Novel Mitochondrial Carnitine-acylcarnitine Translocase Induced by Partial Hepatectomy and Fasting
J. Biol. Chem. 2003 278: 38796-38802. First Published on July 25, 2003; doi:10.1074/jbc.M306372200 [Abstract] [Full Text] [PDF]  

Yan-Yun Liu, James J. Schultz, and Gregory A. Brent
A Thyroid Hormone Receptor {alpha} Gene Mutation (P398H) Is Associated with Visceral Adiposity and Impaired Catecholamine-stimulated Lipolysis in Mice
J. Biol. Chem. 2003 278: 38913-38920. First Published on July 16, 2003; doi:10.1074/jbc.M306120200 [Abstract] [Full Text] [PDF]  

Ludmila Rizhsky, Hongjian Liang, and Ron Mittler
The Water-Water Cycle Is Essential for Chloroplast Protection in the Absence of Stress
J. Biol. Chem. 2003 278: 38921-38925. First Published on July 28, 2003; doi:10.1074/jbc.M304987200 [Abstract] [Full Text] [PDF] Supplemental Data  

Salil Bose, Stephanie French, Frank J. Evans, Fredric Joubert, and Robert S. Balaban
Metabolic Network Control of Oxidative Phosphorylation: MULTIPLE ROLES OF INORGANIC PHOSPHATE
J. Biol. Chem. 2003 278: 39155-39165. First Published on July 18, 2003; doi:10.1074/jbc.M306409200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Shiori Ohtake, Koji Kimata, and Osami Habuchi
A Unique Nonreducing Terminal Modification of Chondroitin Sulfate by N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase
J. Biol. Chem. 2003 278: 38443-38452. First Published on July 21, 2003; doi:10.1074/jbc.M306132200 [Abstract] [Full Text] [PDF]  

Kimika Saito, Toshiki Yajima, Hitoshi Nishimura, Keiko Aiba, Ryotaro Ishimitsu, Tetsuya Matsuguchi, Takashi Fushimi, Yoshifumi Ohshima, Yoshinori Tsukamoto, and Yasunobu Yoshikai
Soluble Branched {beta}-(1,4)Glucans from Acetobacter Species Show Strong Activities to Induce Interleukin-12 in Vitro and Inhibit T-helper 2 Cellular Response with Immunoglobulin E Production in Vivo
J. Biol. Chem. 2003 278: 38571-38578. First Published on June 10, 2003; doi:10.1074/jbc.M304948200 [Abstract] [Full Text] [PDF]  

Mohammad Amraei, Zongjian Jia, Pascal Reboul, and Ivan R. Nabi
Acid-induced Conformational Changes in Phosphoglucose Isomerase Result in Its Increased Cell Surface Association and Deposition on Fibronectin Fibrils
J. Biol. Chem. 2003 278: 38935-38941. First Published on July 29, 2003; doi:10.1074/jbc.M304778200 [Abstract] [Full Text] [PDF]  

Katrin Mani, Fang Cheng, Birgitta Havsmark, Mats Jönsson, Mattias Belting, and Lars-Åke Fransson
Prion, Amyloid {beta}-derived Cu(II) Ions, or Free Zn(II) Ions Support S-Nitroso-dependent Autocleavage of Glypican-1 Heparan Sulfate
J. Biol. Chem. 2003 278: 38956-38965. First Published on May 5, 2003; doi:10.1074/jbc.M300394200 [Abstract] [Full Text] [PDF]  

Sarmishtha De, Juhua Chen, Natalya V. Narizhneva, Warren Heston, Jennifer Brainard, E. Helene Sage, and Tatiana V. Byzova
Molecular Pathway for Cancer Metastasis to Bone
J. Biol. Chem. 2003 278: 39044-39050. First Published on July 28, 2003; doi:10.1074/jbc.M304494200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Atsuyuki Morishima, Nobutaka Ohkubo, Nobuji Maeda, Tetsuro Miki, and Noriaki Mitsuda
NF{kappa}B Regulates Plasma Apolipoprotein A-I and High Density Lipoprotein Cholesterol through Inhibition of Peroxisome Proliferator-activated Receptor {alpha}
J. Biol. Chem. 2003 278: 38188-38193. First Published on July 25, 2003; doi:10.1074/jbc.M306336200 [Abstract] [Full Text] [PDF]  

Maryanne Demasi, Leslie G. Cleland, Rebecca J. Cook-Johnson, Gillian E. Caughey, and Michael J. James
Effects of Hypoxia on Monocyte Inflammatory Mediator Production: DISSOCIATION BETWEEN CHANGES IN CYCLOOXYGENASE-2 EXPRESSION AND EICOSANOID SYNTHESIS
J. Biol. Chem. 2003 278: 38607-38616. First Published on July 21, 2003; doi:10.1074/jbc.M305944200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Danilo Guerini, Bin Pan, and Ernesto Carafoli
Expression, Purification, and Characterization of Isoform 1 of the Plasma Membrane Ca2+ Pump: FOCUS ON CALPAIN SENSITIVITY
J. Biol. Chem. 2003 278: 38141-38148. First Published on July 8, 2003; doi:10.1074/jbc.M302400200 [Abstract] [Full Text] [PDF]  

Shenhui Lang and Michael Palmer
Characterization of Streptococcus agalactiae CAMP Factor as a Pore-forming Toxin
J. Biol. Chem. 2003 278: 38167-38173. First Published on June 30, 2003; doi:10.1074/jbc.M303544200 [Abstract] [Full Text] [PDF]  

Amanda L Gavin, Djemel Aït-Azzouzene, Carl F. Ware, and David Nemazee
{Delta}BAFF, an Alternate Splice Isoform That Regulates Receptor Binding and Biopresentation of the B Cell Survival Cytokine, BAFF
J. Biol. Chem. 2003 278: 38220-38228. First Published on July 16, 2003; doi:10.1074/jbc.M306852200 [Abstract] [Full Text] [PDF]  

Nicolas Wolff, Guillaume Sapriel, Christophe Bodenreider, Alain Chaffotte, and Philippe Delepelaire
Antifolding Activity of the SecB Chaperone Is Essential for Secretion of HasA, a Quickly Folding ABC Pathway Substrate
J. Biol. Chem. 2003 278: 38247-38253. First Published on June 26, 2003; doi:10.1074/jbc.M302322200 [Abstract] [Full Text] [PDF] Supplemental Data  

Toru Ishikawa, Chong Jiang, M. Jackson Stutts, Yoshinori Marunaka, and Daniela Rotin
Regulation of the Epithelial Na+ Channel by Cytosolic ATP
J. Biol. Chem. 2003 278: 38276-38286. First Published on July 22, 2003; doi:10.1074/jbc.M307216200 [Abstract] [Full Text] [PDF]  

Ovidiu I. Pop, Martin Westermann, Rudolf Volkmer-Engert, Daniela Schulz, Cornelius Lemke, Sandra Schreiber, Roman Gerlach, Reinhard Wetzker, and Jörg P. Müller
Sequence-specific Binding of prePhoD to Soluble TatAd Indicates Protein-mediated Targeting of the Tat Export in Bacillus subtilis
J. Biol. Chem. 2003 278: 38428-38436. First Published on July 16, 2003; doi:10.1074/jbc.M306516200 [Abstract] [Full Text] [PDF] Supplemental Data  

Lea F. Payen, Mian Gao, Christopher J. Westlake, Susan P. C. Cole, and Roger G. Deeley
Role of Carboxylate Residues Adjacent to the Conserved Core Walker B Motifs in the Catalytic Cycle of Multidrug Resistance Protein 1 (ABCC1)
J. Biol. Chem. 2003 278: 38537-38547. First Published on July 27, 2003; doi:10.1074/jbc.M305786200 [Abstract] [Full Text] [PDF]  

Takehito Inaba, Ming Li, Mayte Alvarez-Huerta, Felix Kessler, and Danny J. Schnell
atTic110 Functions as a Scaffold for Coordinating the Stromal Events of Protein Import into Chloroplasts
J. Biol. Chem. 2003 278: 38617-38627. First Published on July 21, 2003; doi:10.1074/jbc.M306367200 [Abstract] [Full Text] [PDF]  

Mads Toustrup-Jensen and Bente Vilsen
Functional Consequences of Alterations to Ile279, Ile283, Glu284, His285, Phe286, and His288 in the NH2-terminal Part of Transmembrane Helix M3 of the Na+,K+-ATPase
J. Biol. Chem. 2003 278: 38653-38664. First Published on July 7, 2003; doi:10.1074/jbc.M305521200 [Abstract] [Full Text] [PDF]  

Paul Whitley, Barbara J. Reaves, Makoto Hashimoto, Andrew M. Riley, Barry V. L. Potter, and Geoffrey D. Holman
Identification of Mammalian Vps24p as an Effector of Phosphatidylinositol 3,5-Bisphosphate-dependent Endosome Compartmentalization
J. Biol. Chem. 2003 278: 38786-38795. First Published on July 23, 2003; doi:10.1074/jbc.M306864200 [Abstract] [Full Text] [PDF]  

Carsten Strübing, Grigory Krapivinsky, Luba Krapivinsky, and David E. Clapham
Formation of Novel TRPC Channels by Complex Subunit Interactions in Embryonic Brain
J. Biol. Chem. 2003 278: 39014-39019. First Published on July 11, 2003; doi:10.1074/jbc.M306705200 [Abstract] [Full Text] [PDF] Supplemental Data  

Keiichi Katoh, Hideki Shibata, Hidenori Suzuki, Atsuki Nara, Kazumi Ishidoh, Eiki Kominami, Tamotsu Yoshimori, and Masatoshi Maki
The ALG-2-interacting Protein Alix Associates with CHMP4b, a Human Homologue of Yeast Snf7 That Is Involved in Multivesicular Body Sorting
J. Biol. Chem. 2003 278: 39104-39113. First Published on July 14, 2003; doi:10.1074/jbc.M301604200 [Abstract] [Full Text] [PDF]  

Takashi Daiho, Kazuo Yamasaki, Guoli Wang, Stefania Danko, Hajime Iizuka, and Hiroshi Suzuki
Deletions of Any Single Residues in Glu40-Ser48 Loop Connecting A Domain and the First Transmembrane Helix of Sarcoplasmic Reticulum Ca2+-ATPase Result in Almost Complete Inhibition of Conformational Transition and Hydrolysis of Phosphoenzyme Intermediate
J. Biol. Chem. 2003 278: 39197-39204. First Published on July 11, 2003; doi:10.1074/jbc.M305200200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Alexandre Chigaev, Gordon Zwartz, Steven W. Graves, Denise C. Dwyer, Hisashi Tsuji, Terry D. Foutz, Bruce S. Edwards, Eric R. Prossnitz, Richard S. Larson, and Larry A. Sklar
{alpha}4{beta}1 Integrin Affinity Changes Govern Cell Adhesion
J. Biol. Chem. 2003 278: 38174-38182. First Published on July 3, 2003; doi:10.1074/jbc.M210472200 [Abstract] [Full Text] [PDF]  

Gisela D'Angelo, Eric Duplan, Nicole Boyer, Paul Vigne, and Christian Frelin
Hypoxia Up-regulates Prolyl Hydroxylase Activity: A FEEDBACK MECHANSIM THAT LIMITS HIF-1 RESPONSES DURING REOXYGENATION
J. Biol. Chem. 2003 278: 38183-38187. First Published on July 21, 2003; doi:10.1074/jbc.M302244200 [Abstract] [Full Text] [PDF]  

Benjamin J. Pettus, Alicja Bielawska, Sarah Spiegel, Patrick Roddy, Yusuf A. Hannun, and Charles E. Chalfant
Ceramide Kinase Mediates Cytokine- and Calcium Ionophore-induced Arachidonic Acid Release
J. Biol. Chem. 2003 278: 38206-38213. First Published on July 10, 2003; doi:10.1074/jbc.M304816200 [Abstract] [Full Text] [PDF] Supplemental Data  

Giorgia Santilli, Bruce J. Aronow, and Arturo Sala
Essential Requirement of Apolipoprotein J (Clusterin) Signaling for I{kappa}B Expression and Regulation of NF-{kappa}B Activity
J. Biol. Chem. 2003 278: 38214-38219. First Published on July 25, 2003; doi:10.1074/jbc.C300252200 [Abstract] [Full Text] [PDF]  

Sujin Yim, Su Mi Choi, Youngyeon Choi, Naery Lee, Jieun Chung, and Hyunsung Park
Insulin and Hypoxia Share Common Target Genes but Not the Hypoxia-inducible Factor-1{alpha}
J. Biol. Chem. 2003 278: 38260-38268. First Published on July 21, 2003; doi:10.1074/jbc.M306016200 [Abstract] [Full Text] [PDF]  

Kyung Song, Susan C. Cornelius, Michael Reiss, and David Danielpour
Insulin-like Growth Factor-I Inhibits Transcriptional Responses of Transforming Growth Factor-{beta} by Phosphatidylinositol 3-Kinase/Akt-dependent Suppression of the Activation of Smad3 but Not Smad2
J. Biol. Chem. 2003 278: 38342-38351. First Published on July 21, 2003; doi:10.1074/jbc.M304583200 [Abstract] [Full Text] [PDF]  

Kotb Abdelmohsen, P. Arne Gerber, Claudia von Montfort, Helmut Sies, and Lars-Oliver Klotz
Epidermal Growth Factor Receptor Is a Common Mediator of Quinone-induced Signaling Leading to Phosphorylation of Connexin-43: ROLE OF GLUTATHIONE AND TYROSINE PHOSPHATASES
J. Biol. Chem. 2003 278: 38360-38367. First Published on July 21, 2003; doi:10.1074/jbc.M306785200 [Abstract] [Full Text] [PDF]  

Ken-ichi Sato, Alexander A. Tokmakov, Chang-Li He, Manabu Kurokawa, Tetsushi Iwasaki, Mikako Shirouzu, Rafael A. Fissore, Shigeyuki Yokoyama, and Yasuo Fukami
Reconstitution of Src-dependent Phospholipase C{gamma} Phosphorylation and Transient Calcium Release by Using Membrane Rafts and Cell-free Extracts from Xenopus Eggs
J. Biol. Chem. 2003 278: 38413-38420. First Published on July 7, 2003; doi:10.1074/jbc.M302617200 [Abstract] [Full Text] [PDF]  

Qiu-Chen Cheng, Oleg Tikhomirov, Wenli Zhou, and Graham Carpenter
Ectodomain Cleavage of ErbB-4: CHARACTERIZATION OF THE CLEAVAGE SITE AND m80 FRAGMENT
J. Biol. Chem. 2003 278: 38421-38427. First Published on July 16, 2003; doi:10.1074/jbc.M302111200 [Abstract] [Full Text] [PDF]  

Yann Leverrier, Klaus Okkenhaug, Carol Sawyer, Antonio Bilancio, Bart Vanhaesebroeck, and Anne J. Ridley
Class I Phosphoinositide 3-Kinase p110{beta} Is Required for Apoptotic Cell and Fc{gamma} Receptor-mediated Phagocytosis by Macrophages
J. Biol. Chem. 2003 278: 38437-38442. First Published on July 16, 2003; doi:10.1074/jbc.M306649200 [Abstract] [Full Text] [PDF]  

Eric M. Muller, Nancy A. Mackin, Scott E. Erdman, and Kyle W. Cunningham
Fig1p Facilitates Ca2+ Influx and Cell Fusion during Mating of Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 38461-38469. First Published on July 23, 2003; doi:10.1074/jbc.M304089200 [Abstract] [Full Text] [PDF] Supplemental Data  

Anita S. Galvez, Juan Alberto Ulloa, Mario Chiong, Alfredo Criollo, Verónica Eisner, Luis Felipe Barros, and Sergio Lavandero
Aldose Reductase Induced by Hyperosmotic Stress Mediates Cardiomyocyte Apoptosis: DIFFERENTIAL EFFECTS OF SORBITOL AND MANNITOL
J. Biol. Chem. 2003 278: 38484-38494. First Published on July 24, 2003; doi:10.1074/jbc.M211824200 [Abstract] [Full Text] [PDF]  

Mohammed El-Azami-El-Idrissi, Cécile Bauche, Jirina Loucka, Radim Osicka, Peter Sebo, Daniel Ladant, and Claude Leclerc
Interaction of Bordetella pertussis Adenylate Cyclase with CD11b/CD18: ROLE OF TOXIN ACYLATION AND IDENTIFICATION OF THE MAIN INTEGRIN INTERACTION DOMAIN
J. Biol. Chem. 2003 278: 38514-38521. First Published on July 28, 2003; doi:10.1074/jbc.M304387200 [Abstract] [Full Text] [PDF]  

Holger Rehmann, Frank Schwede, Stein O. Døskeland, Alfred Wittinghofer, and Johannes L. Bos
Ligand-mediated Activation of the cAMP-responsive Guanine Nucleotide Exchange Factor Epac
J. Biol. Chem. 2003 278: 38548-38556. First Published on July 29, 2003; doi:10.1074/jbc.M306292200 [Abstract] [Full Text] [PDF]  

Eric D. Tang, Naohiro Inohara, Cun-Yu Wang, Gabriel Nuñez, and Kun-Liang Guan
Roles for Homotypic Interactions and Transautophosphorylation in I{kappa}B Kinase (IKK{beta}) Activation
J. Biol. Chem. 2003 278: 38566-38570. First Published on July 30, 2003; doi:10.1074/jbc.M304374200 [Abstract] [Full Text] [PDF]  

Shuji Matsuda, Yukiko Matsuda, and Luciano D'Adamio
Amyloid {beta} Protein Precursor (A{beta}PP), but Not A{beta}PP-like Protein 2, Is Bridged to the Kinesin Light Chain by the Scaffold Protein JNK-interacting Protein 1
J. Biol. Chem. 2003 278: 38601-38606. First Published on July 31, 2003; doi:10.1074/jbc.M304379200 [Abstract] [Full Text] [PDF]  

Christopher P. Baran, Susheela Tridandapani, Cheryl D. Helgason, R. Keith Humphries, Gerald Krystal, and Clay B. Marsh
The Inositol 5'-Phosphatase SHIP-1 and the Src Kinase Lyn Negatively Regulate Macrophage Colony-stimulating Factor-induced Akt Activity
J. Biol. Chem. 2003 278: 38628-38636. First Published on July 25, 2003; doi:10.1074/jbc.M305021200 [Abstract] [Full Text] [PDF]  

Yong Li, Long-Jun Wu, Pascal Legendre, and Tian-Le Xu
Asymmetric Cross-inhibition between GABAA and Glycine Receptors in Rat Spinal Dorsal Horn Neurons
J. Biol. Chem. 2003 278: 38637-38645. First Published on July 28, 2003; doi:10.1074/jbc.M303735200 [Abstract] [Full Text] [PDF]  

Jui-Cheng Hsieh, Jeanne M. Sisk, Peter W. Jurutka, Carol A. Haussler, Stephanie A. Slater, Mark R. Haussler, and Catherine C. Thompson
Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling
J. Biol. Chem. 2003 278: 38665-38674. First Published on July 7, 2003; doi:10.1074/jbc.M304886200 [Abstract] [Full Text] [PDF]  

Rolf Jakobi, Corine C. McCarthy, Mark A. Koeppel, and Daniel K. Stringer
Caspase-activated PAK-2 Is Regulated by Subcellular Targeting and Proteasomal Degradation
J. Biol. Chem. 2003 278: 38675-38685. First Published on July 9, 2003; doi:10.1074/jbc.M306494200 [Abstract] [Full Text] [PDF]  

Francesco Massimo Lasorsa, Paolo Pinton, Luigi Palmieri, Giuseppe Fiermonte, Rosario Rizzuto, and Ferdinando Palmieri
Recombinant Expression of the Ca2+-sensitive Aspartate/Glutamate Carrier Increases Mitochondrial ATP Production in Agonist-stimulated Chinese Hamster Ovary Cells
J. Biol. Chem. 2003 278: 38686-38692. First Published on July 8, 2003; doi:10.1074/jbc.M304988200 [Abstract] [Full Text] [PDF]  

Nathan Airhart, Yong-Feng Yang, Charles T. Roberts, Jr., and Michael Silberbach
Atrial Natriuretic Peptide Induces Natriuretic Peptide Receptor-cGMP-dependent Protein Kinase Interaction
J. Biol. Chem. 2003 278: 38693-38698. First Published on July 10, 2003; doi:10.1074/jbc.M304098200 [Abstract] [Full Text] [PDF]  

Ramesh Hegde, Srinivasa M. Srinivasula, Pinaki Datta, Muniswamy Madesh, Richard Wassell, ZhiJia Zhang, NaEun Cheong, Julie Nejmeh, Teresa Fernandes-Alnemri, Shin-ichi Hoshino, and Emad S. Alnemri
The Polypeptide Chain-releasing Factor GSPT1/eRF3 Is Proteolytically Processed into an IAP-binding Protein
J. Biol. Chem. 2003 278: 38699-38706. First Published on July 15, 2003; doi:10.1074/jbc.M303179200 [Abstract] [Full Text] [PDF]  

Yu Pong Ng, Wei He, and Nancy Y. Ip
Leukemia Inhibitory Factor Receptor Signaling Negatively Modulates Nerve Growth Factor-induced Neurite Outgrowth in PC12 Cells and Sympathetic Neurons
J. Biol. Chem. 2003 278: 38731-38739. First Published on July 18, 2003; doi:10.1074/jbc.M304623200 [Abstract] [Full Text] [PDF]  

Mutsumi Kanamori, Peter Sandy, Stefania Marzinotto, Roberta Benetti, Chikatoshi Kai, Yoshihide Hayashizaki, Claudio Schneider, and Harukazu Suzuki
The PDZ Protein Tax-interacting Protein-1 Inhibits {beta}-Catenin Transcriptional Activity and Growth of Colorectal Cancer Cells
J. Biol. Chem. 2003 278: 38758-38764. First Published on July 21, 2003; doi:10.1074/jbc.M306324200 [Abstract] [Full Text] [PDF]  

Hans H. Bock, Yves Jossin, Pingsheng Liu, Eckart Förster, Petra May, André M. Goffinet, and Joachim Herz
Phosphatidylinositol 3-Kinase Interacts with the Adaptor Protein Dab1 in Response to Reelin Signaling and Is Required for Normal Cortical Lamination
J. Biol. Chem. 2003 278: 38772-38779. First Published on July 25, 2003; doi:10.1074/jbc.M306416200 [Abstract] [Full Text] [PDF]  

Nilda M. Muñoz, Young Jun Kim, Angelo Y. Meliton, Kwang Pyo Kim, Sang-Kyou Han, Evan Boetticher, Eileen O'Leary, Shigeharu Myou, Xiangdong Zhu, Joseph V. Bonventre, Alan R. Leff, and Wonhwa Cho
Human Group V Phospholipase A2 Induces Group IVA Phospholipase A2-independent Cysteinyl Leukotriene Synthesis in Human Eosinophils
J. Biol. Chem. 2003 278: 38813-38820. First Published on June 9, 2003; doi:10.1074/jbc.M302476200 [Abstract] [Full Text] [PDF]  

Vance Matthews, Björn Schuster, Stefan Schütze, Ingo Bussmeyer, Andreas Ludwig, Christian Hundhausen, Thorsten Sadowski, Paul Saftig, Dieter Hartmann, Karl-Josef Kallen, and Stefan Rose-John
Cellular Cholesterol Depletion Triggers Shedding of the Human Interleukin-6 Receptor by ADAM10 and ADAM17 (TACE)
J. Biol. Chem. 2003 278: 38829-38839. First Published on June 27, 2003; doi:10.1074/jbc.M210584200 [Abstract] [Full Text] [PDF] Supplemental Data  

Hiroshi Sakaue, Akihiko Nishizawa, Wataru Ogawa, Kiyoshi Teshigawara, Toshiyuki Mori, Yasuhiro Takashima, Tetsuo Noda, and Masato Kasuga
Requirement for 3-Phosphoinositide-dependent Kinase-1 (PDK-1) in Insulin-induced Glucose Uptake in Immortalized Brown Adipocytes
J. Biol. Chem. 2003 278: 38870-38874. First Published on July 10, 2003; doi:10.1074/jbc.M306151200 [Abstract] [Full Text] [PDF]  

Fernand Gobeil, Jr., Sylvie G. Bernier, Alejandro Vazquez-Tello, Sonia Brault, Martin H. Beauchamp, Christiane Quiniou, Anne Marilise Marrache, Daniella Checchin, Florian Sennlaub, Xin Hou, Mony Nader, Ghassan Bkaily, Alfredo Ribeiro-da-Silva, Edward J. Goetzl, and Sylvain Chemtob
Modulation of Pro-inflammatory Gene Expression by Nuclear Lysophosphatidic Acid Receptor Type-1
J. Biol. Chem. 2003 278: 38875-38883. First Published on July 7, 2003; doi:10.1074/jbc.M212481200 [Abstract] [Full Text] [PDF]  

Paul Déléris, Daniel Bacqueville, Stéphanie Gayral, Laurent Carrez, Jean-Pierre Salles, Bertrand Perret, and Monique Breton-Douillon
SHIP-2 and PTEN Are Expressed and Active in Vascular Smooth Muscle Cell Nuclei, but Only SHIP-2 Is Associated with Nuclear Speckles
J. Biol. Chem. 2003 278: 38884-38891. First Published on July 7, 2003; doi:10.1074/jbc.M300816200 [Abstract] [Full Text] [PDF]  

Jun Harada, Kenji Kokura, Chie Kanei-Ishii, Teruaki Nomura, Md Matiullah Khan, Yongsok Kim, and Shunsuke Ishii
Requirement of the Co-repressor Homeodomain-interacting Protein Kinase 2 for Ski-mediated Inhibition of Bone Morphogenetic Protein-induced Transcriptional Activation
J. Biol. Chem. 2003 278: 38998-39005. First Published on July 21, 2003; doi:10.1074/jbc.M307112200 [Abstract] [Full Text] [PDF]  

Young-Gun Yoo, Seung Hyun Oh, Eun Sook Park, Hyeseong Cho, Naery Lee, Hyunsung Park, Dae Kyong Kim, Dae-Yeul Yu, Je Kyung Seong, and Mi-Ock Lee
Hepatitis B Virus X Protein Enhances Transcriptional Activity of Hypoxia-inducible Factor-1{alpha} through Activation of Mitogen-activated Protein Kinase Pathway
J. Biol. Chem. 2003 278: 39076-39084. First Published on July 10, 2003; doi:10.1074/jbc.M305101200 [Abstract] [Full Text] [PDF]  

Paula B. van Hennik, Jean Paul ten Klooster, Jon R. Halstead, Carlijn Voermans, Eloise C. Anthony, Nullin Divecha, and Peter L. Hordijk
The C-terminal Domain of Rac1 Contains Two Motifs That Control Targeting and Signaling Specificity
J. Biol. Chem. 2003 278: 39166-39175. First Published on July 21, 2003; doi:10.1074/jbc.M307001200 [Abstract] [Full Text] [PDF] Supplemental Data  

Carl D. Bortner and John A. Cidlowski
Uncoupling Cell Shrinkage from Apoptosis Reveals That Na+ Influx Is Required for Volume Loss during Programmed Cell Death
J. Biol. Chem. 2003 278: 39176-39184. First Published on June 23, 2003; doi:10.1074/jbc.M303516200 [Abstract] [Full Text] [PDF]  

Bernd Giese, Chi-King Au-Yeung, Andreas Herrmann, Sandra Diefenbach, Claude Haan, Andrea Küster, Saskia B. Wortmann, Christoph Roderburg, Peter C. Heinrich, Iris Behrmann, and Gerhard Müller-Newen
Long Term Association of the Cytokine Receptor gp130 and the Janus Kinase Jak1 Revealed by FRAP Analysis
J. Biol. Chem. 2003 278: 39205-39213. First Published on July 23, 2003; doi:10.1074/jbc.M303347200 [Abstract] [Full Text] [PDF]  

Luisa Filippin, Paulo J. Magalhães, Giulietta Di Benedetto, Matilde Colella, and Tullio Pozzan
Stable Interactions between Mitochondria and Endoplasmic Reticulum Allow Rapid Accumulation of Calcium in a Subpopulation of Mitochondria
J. Biol. Chem. 2003 278: 39224-39234. First Published on July 21, 2003; doi:10.1074/jbc.M302301200 [Abstract] [Full Text] [PDF]  

Harald Jakob Maier, Ralf Marienfeld, Thomas Wirth, and Bernd Baumann
Critical Role of RelB Serine 368 for Dimerization and p100 Stabilization
J. Biol. Chem. 2003 278: 39242-39250. First Published on July 21, 2003; doi:10.1074/jbc.M301521200 [Abstract] [Full Text] [PDF]  

Leng Wen, Li Zhuang, Xia Luo, and Ping Wei
TL1A-induced NF-{kappa}B Activation and c-IAP2 Production Prevent DR3-mediated Apoptosis in TF-1 Cells
J. Biol. Chem. 2003 278: 39251-39258. First Published on July 25, 2003; doi:10.1074/jbc.M305833200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Dennis C. Chang, Harriet G. McWatters, Julie A. Williams, Anthony L. Gotter, Joel D. Levine, and Steven M. Reppert
Constructing a Feedback Loop with Circadian Clock Molecules from the Silkmoth, Antheraea pernyi
J. Biol. Chem. 2003 278: 38149-38158. First Published on July 17, 2003; doi:10.1074/jbc.M306937200 [Abstract] [Full Text] [PDF] Supplemental Data  

Robert Rauchenberger, Eric Borges, Elisabeth Thomassen-Wolf, Eran Rom, Rivka Adar, Yael Yaniv, Michael Malka, Irina Chumakov, Sarit Kotzer, Dalia Resnitzky, Achim Knappik, Silke Reiffert, Josef Prassler, Karin Jury, Dirk Waldherr, Susanne Bauer, Titus Kretzschmar, Avner Yayon, and Christine Rothe
Human Combinatorial Fab Library Yielding Specific and Functional Antibodies against the Human Fibroblast Growth Factor Receptor 3
J. Biol. Chem. 2003 278: 38194-38205. First Published on July 3, 2003; doi:10.1074/jbc.M303164200 [Abstract] [Full Text] [PDF]  

Stuart B. Smith, Rosa Gasa, Hirotaka Watada, Juehu Wang, Steven C. Griffen, and Michael S. German
Neurogenin3 and Hepatic Nuclear Factor 1 Cooperate in Activating Pancreatic Expression of Pax4
J. Biol. Chem. 2003 278: 38254-38259. First Published on July 1, 2003; doi:10.1074/jbc.M302229200 [Abstract] [Full Text] [PDF]  

Lei Sun, Mary A. Bittner, and Ronald W. Holz
Rim, a Component of the Presynaptic Active Zone and Modulator of Exocytosis, Binds 14-3-3 through Its N Terminus
J. Biol. Chem. 2003 278: 38301-38309. First Published on July 18, 2003; doi:10.1074/jbc.M212801200 [Abstract] [Full Text] [PDF]  

Megan R. McMullen, Enzo Cocuzzi, Maria Hatzoglou, and Laura E. Nagy
Chronic Ethanol Exposure Increases the Binding of HuR to the TNF{alpha} 3'-Untranslated Region in Macrophages
J. Biol. Chem. 2003 278: 38333-38341. First Published on July 21, 2003; doi:10.1074/jbc.M304566200 [Abstract] [Full Text] [PDF]  

Carla Emiliani, Lorena Urbanelli, Leda Racanicchi, Antonio Orlacchio, Giuliana Pelicci, Sandro Sorbi, Giorgio Bernardi, and Aldo Orlacchio
Up-regulation of Glycohydrolases in Alzheimer's Disease Fibroblasts Correlates with Ras Activation
J. Biol. Chem. 2003 278: 38453-38460. First Published on July 23, 2003; doi:10.1074/jbc.M303030200 [Abstract] [Full Text] [PDF]  

Yasuko Matsumoto, Yasunori Oda, Masahide Uryu, and Yoichi Hayakawa
Insect Cytokine Growth-blocking Peptide Triggers a Termination System of Cellular Immunity by Inducing Its Binding Protein
J. Biol. Chem. 2003 278: 38579-38585. First Published on July 18, 2003; doi:10.1074/jbc.M305986200 [Abstract] [Full Text] [PDF]  

Daisuke Tsuruta, Susan B. Hopkinson, Kimberly D. Lane, Michael E. Werner, Vincent L. Cryns, and Jonathan C. R. Jones
Crucial Role of the Specificity-determining Loop of the Integrin {beta}4 Subunit in the Binding of Cells to Laminin-5 and Outside-in Signal Transduction
J. Biol. Chem. 2003 278: 38707-38714. First Published on July 16, 2003; doi:10.1074/jbc.M301637200 [Abstract] [Full Text] [PDF]  

Darrell D. Mousseau, Sarah Chapelsky, Gregory De Crescenzo, Marina D. Kirkitadze, Joanne Magoon, Sadayuki Inoue, David B. Teplow, and Maureen D. O'Connor-McCourt
A Direct Interaction between Transforming Growth Factor (TGF)-{beta}s and Amyloid-{beta} Protein Affects Fibrillogenesis in a TGF-{beta}Receptor-independent Manner
J. Biol. Chem. 2003 278: 38715-38722. First Published on July 16, 2003; doi:10.1074/jbc.M304080200 [Abstract] [Full Text] [PDF]  

Michal Caspi, Frédéric M. Coquelle, Cynthia Koifman, Talia Levy, Hiroyuki Arai, Junken Aoki, Jan R. De Mey, and Orly Reiner
LIS1 Missense Mutations: VARIABLE PHENOTYPES RESULT FROM UNPREDICTABLE ALTERATIONS IN BIOCHEMICAL AND CELLULAR PROPERTIES
J. Biol. Chem. 2003 278: 38740-38748. First Published on July 28, 2003; doi:10.1074/jbc.M301147200 [Abstract] [Full Text] [PDF]  

Judith E. Gasteier, Ricardo Madrid, Ellen Krautkrämer, Sebastian Schröder, Walter Muranyi, Serge Benichou, and Oliver T. Fackler
Activation of the Rac-binding Partner FHOD1 Induces Actin Stress Fibers via a ROCK-dependent Mechanism
J. Biol. Chem. 2003 278: 38902-38912. First Published on July 10, 2003; doi:10.1074/jbc.M306229200 [Abstract] [Full Text] [PDF]  

Jörg Piontek and Roland Brandt
Differential and Regulated Binding of cAMP-dependent Protein Kinase and Protein Kinase C Isoenzymes to Gravin in Human Model Neurons: EVIDENCE THAT GRAVIN PROVIDES A DYNAMIC PLATFORM FOR THE LOCALIZATION OF KINASES DURING NEURONAL DEVELOPMENT
J. Biol. Chem. 2003 278: 38970-38979. First Published on July 10, 2003; doi:10.1074/jbc.M306749200 [Abstract] [Full Text] [PDF]  

Mary B. Breslin, Min Zhu, and Michael S. Lan
NeuroD1/E47 Regulates the E-box Element of a Novel Zinc Finger Transcription Factor, IA-1, in Developing Nervous System
J. Biol. Chem. 2003 278: 38991-38997. First Published on July 30, 2003; doi:10.1074/jbc.M306795200 [Abstract] [Full Text] [PDF]  

Sai-Xia Ying, Zareena J. Hussain, and Ying E. Zhang
Smurf1 Facilitates Myogenic Differentiation and Antagonizes the Bone Morphogenetic Protein-2-induced Osteoblast Conversion by Targeting Smad5 for Degradation
J. Biol. Chem. 2003 278: 39029-39036. First Published on July 18, 2003; doi:10.1074/jbc.M301193200 [Abstract] [Full Text] [PDF]  

Lisa M. Klumpp, Andrew T. Mackey, Christopher M. Farrell, John M. Rosenberg, and Susan P. Gilbert
A Kinesin Switch I Arginine to Lysine Mutation Rescues Microtubule Function
J. Biol. Chem. 2003 278: 39059-39067. First Published on July 14, 2003; doi:10.1074/jbc.M304250200 [Abstract] [Full Text] [PDF]  

Masaki Mogi, Jiang Yang, Jean-Francois Lambert, Gerald A. Colvin, Ichiro Shiojima, Carsten Skurk, Ross Summer, Alan Fine, Peter J. Quesenberry, and Kenneth Walsh
Akt Signaling Regulates Side Population Cell Phenotype via Bcrp1 Translocation
J. Biol. Chem. 2003 278: 39068-39075. First Published on July 8, 2003; doi:10.1074/jbc.M306362200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Tommi J. Ahonen, Jianwu Xie, Matthew J. LeBaron, Jianqiong Zhu, Martti Nurmi, Kalle Alanen, Hallgeir Rui, and Marja T. Nevalainen
Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells.
J. Biol. Chem. 2003 278: 39259. [Full Text] [PDF]  

Uwe Heinz, Rogert Bauer, Sandra Wommer, Wolfram Meyer-Klaucke, Cyril Papamicaël, John Bateson, and Hans-Werner Adolph
Coordination geometries of metal ions in D- or L-captopril-inhibited metallo-{beta}-lactamases.
J. Biol. Chem. 2003 278: 39260. [Full Text] [PDF]  

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