Minireviews:

Julie G. Donaldson

Multiple Roles for Arf6: Sorting, Structuring, and Signaling at the Plasma Membrane
J. Biol. Chem. 2003 278: 41573-41576. First Published on August 11, 2003; doi:10.1074/jbc.R300026200 [Full Text] [PDF]  

Accelerated Publications:

Andrey P. Babenko and Joseph Bryan

SUR Domains That Associate with and Gate K_ATP Pores Define a Novel Gatekeeper
J. Biol. Chem. 2003 278: 41577-41580. First Published on August 26, 2003; doi:10.1074/jbc.C300363200 [Abstract] [Full Text] [PDF] Supplemental Data  

Charlotte M. Vines, Chetana M. Revankar, Diane C. Maestas, Leah L. LaRusch, Daniel F. Cimino, Trudy A. Kohout, Robert J. Lefkowitz, and Eric R. Prossnitz

N-Formyl Peptide Receptors Internalize but Do Not Recycle in the Absence of Arrestins
J. Biol. Chem. 2003 278: 41581-41584. First Published on August 28, 2003; doi:10.1074/jbc.C300291200 [Abstract] [Full Text] [PDF]  

Elizabeth C. Alappat, Jörg Volkland, and Marcus E. Peter

Cell Cycle Effects by C-FADD Depend on Its C-terminal Phosphorylation Site
J. Biol. Chem. 2003 278: 41585-41588. First Published on September 3, 2003; doi:10.1074/jbc.C300385200 [Abstract] [Full Text] [PDF]  

Natacha Shaw, Morten Elholm, and Noa Noy

Retinoic Acid Is a High Affinity Selective Ligand for the Peroxisome Proliferator-activated Receptor /
J. Biol. Chem. 2003 278: 41589-41592. First Published on September 8, 2003; doi:10.1074/jbc.C300368200 [Abstract] [Full Text] [PDF]  

Ting Y. Tao, Fengli Liu, Leo Klomp, Cisca Wijmenga, and Jonathan D. Gitlin

The Copper Toxicosis Gene Product Murr1 Directly Interacts with the Wilson Disease Protein
J. Biol. Chem. 2003 278: 41593-41596. First Published on September 10, 2003; doi:10.1074/jbc.C300391200 [Abstract] [Full Text] [PDF]  

DNA: Replication, Repair, and Recombination:

Durga Udayakumar, Catherine L. Bladen, Farlyn Z. Hudson, and William S. Dynan

Distinct Pathways of Nonhomologous End Joining That Are Differentially Regulated by DNA-dependent Protein Kinase-mediated Phosphorylation
J. Biol. Chem. 2003 278: 41631-41635. First Published on August 12, 2003; doi:10.1074/jbc.M306470200 [Abstract] [Full Text] [PDF]  

Lyudmila Yakovleva, Ligeng Tian, Jane M. Sayer, Govind P. Kalena, Heiko Kroth, Donald M. Jerina, and Stewart Shuman

Site-specific DNA Transesterification by Vaccinia Topoisomerase: EFFECTS OF BENZO[]PYRENE-dA, 8-OXOGUANINE, 8-OXOADENINE, AND 2-AMINOPURINE MODIFICATIONS
J. Biol. Chem. 2003 278: 42170-42177. First Published on August 8, 2003; doi:10.1074/jbc.M308079200 [Abstract] [Full Text] [PDF] Supplemental Data  

Toshimi Mizukoshi, Taku Tanaka, Ken-ichi Arai, Daisuke Kohda, and Hisao Masai

A Critical Role of the 3' Terminus of Nascent DNA Chains in Recognition of Stalled Replication Forks
J. Biol. Chem. 2003 278: 42234-42239. First Published on August 13, 2003; doi:10.1074/jbc.C300285200 [Abstract] [Full Text] [PDF] Supplemental Data  

Jeffrey C. Myers, Sheila A. Moore, and Yousif Shamoo

Structure-based Incorporation of 6-Methyl-8-(2-deoxy--ribofuranosyl)isoxanthopteridine into the Human Telomeric Repeat DNA as a Probe for UP1 Binding and Destabilization of G-tetrad Structures
J. Biol. Chem. 2003 278: 42300-42306. First Published on August 6, 2003; doi:10.1074/jbc.M306147200 [Abstract] [Full Text] [PDF]  

Frank G. Harmon, Joel P. Brockman, and Stephen C. Kowalczykowski

RecQ Helicase Stimulates Both DNA Catenation and Changes in DNA Topology by Topoisomerase III
J. Biol. Chem. 2003 278: 42668-42678. First Published on August 8, 2003; doi:10.1074/jbc.M302994200 [Abstract] [Full Text] [PDF]  

Leticia Odriozola, Carlos Cruchaga, Marieline Andréola, Valérie Dollé, Chi Hung Nguyen, Laura Tarrago-Litvak, Alberto Pérez-Mediavilla, and Juan J. Martínez-Irujo

Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase Inhibit Phosphorolysis and Resensitize the 3'-Azido-3'-deoxythymidine (AZT)-resistant Polymerase to AZT-5'-triphosphate
J. Biol. Chem. 2003 278: 42710-42716. First Published on August 13, 2003; doi:10.1074/jbc.M212673200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Steven J. Kim and Harold G. Martinson

Poly(A)-dependent Transcription Termination: CONTINUED COMMUNICATION OF THE POLY(A) SIGNAL WITH THE POLYMERASE IS REQUIRED LONG AFTER EXTRUSION IN VIVO
J. Biol. Chem. 2003 278: 41691-41701. First Published on August 21, 2003; doi:10.1074/jbc.M306304200 [Abstract] [Full Text] [PDF]  

Alan Holmes, David J. Abraham, Youjun Chen, Christopher Denton, Xu Shi-wen, Carol M. Black, and Andrew Leask

Constitutive Connective Tissue Growth Factor Expression in Scleroderma Fibroblasts Is Dependent on Sp1
J. Biol. Chem. 2003 278: 41728-41733. First Published on July 29, 2003; doi:10.1074/jbc.M305019200 [Abstract] [Full Text] [PDF]  

Ahalya Selvaraj and Ron Prywes

Megakaryoblastic Leukemia-1/2, a Transcriptional Co-activator of Serum Response Factor, Is Required for Skeletal Myogenic Differentiation
J. Biol. Chem. 2003 278: 41977-41987. First Published on August 14, 2003; doi:10.1074/jbc.M305679200 [Abstract] [Full Text] [PDF]  

Anthony J. Saporita, Qiuheng Zhang, Neema Navai, Zehra Dincer, Junghyun Hahn, Xiaoyan Cai, and Zhou Wang

Identification and Characterization of a Ligand-regulated Nuclear Export Signal in Androgen Receptor
J. Biol. Chem. 2003 278: 41998-42005. First Published on August 15, 2003; doi:10.1074/jbc.M302460200 [Abstract] [Full Text] [PDF]  

Alain de Bruin, Baidehi Maiti, Laszlo Jakoi, Cynthia Timmers, Robin Buerki, and Gustavo Leone

Identification and Characterization of E2F7, a Novel Mammalian E2F Family Member Capable of Blocking Cellular Proliferation
J. Biol. Chem. 2003 278: 42041-42049. First Published on July 31, 2003; doi:10.1074/jbc.M308105200 [Abstract] [Full Text] [PDF]  

Kevin M. McCarthy, Daniel McDevit, Amy Andreucci, Raymond Reeves, and Barbara S. Nikolajczyk

HMGA1 Co-activates Transcription in B Cells through Indirect Association with DNA
J. Biol. Chem. 2003 278: 42106-42114. First Published on August 7, 2003; doi:10.1074/jbc.M308586200 [Abstract] [Full Text] [PDF]  

Tae-Gyun Kim, Jonathan C. Kraus, Junqin Chen, and Youngsook Lee

JUMONJI, a Critical Factor for Cardiac Development, Functions as a Transcriptional Repressor
J. Biol. Chem. 2003 278: 42247-42255. First Published on July 30, 2003; doi:10.1074/jbc.M307386200 [Abstract] [Full Text] [PDF]  

Matthew J. Oberley, David R. Inman, and Peggy J. Farnham

E2F6 Negatively Regulates BRCA1 in Human Cancer Cells without Methylation of Histone H3 on Lysine 9
J. Biol. Chem. 2003 278: 42466-42476. First Published on August 8, 2003; doi:10.1074/jbc.M307733200 [Abstract] [Full Text] [PDF]  

Teruo Sugawara, Hiroshi Shimizu, Nobuhiko Hoshi, Ayako Nakajima, and Seiichiro Fujimoto

Steroidogenic Acute Regulatory Protein-binding Protein Cloned by a Yeast Two-hybrid System
J. Biol. Chem. 2003 278: 42487-42494. First Published on August 8, 2003; doi:10.1074/jbc.M302291200 [Abstract] [Full Text] [PDF]  

Ya-Li Yao and Wen-Ming Yang

The Metastasis-associated Proteins 1 and 2 Form Distinct Protein Complexes with Histone Deacetylase Activity
J. Biol. Chem. 2003 278: 42560-42568. First Published on August 13, 2003; doi:10.1074/jbc.M302955200 [Abstract] [Full Text] [PDF]  

Jacques J. Tremblay and Robert S. Viger

A Mutated Form of Steroidogenic Factor 1 (SF-1 G35E) That Causes Sex Reversal in Humans Fails to Synergize with Transcription Factor GATA-4
J. Biol. Chem. 2003 278: 42637-42642. First Published on August 6, 2003; doi:10.1074/jbc.M305485200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Lidia Vasiljeva, Andres Merits, Andrey Golubtsov, Valeria Sizemskaja, Leevi Kääriäinen, and Tero Ahola

Regulation of the Sequential Processing of Semliki Forest Virus Replicase Polyprotein
J. Biol. Chem. 2003 278: 41636-41645. First Published on August 12, 2003; doi:10.1074/jbc.M307481200 [Abstract] [Full Text] [PDF]  

Elisabetta Bergantino, Alessia Brunetta, Eleftherios Touloupakis, Anna Segalla, Ildikò Szabò, and Giorgio Mario Giacometti

Role of the PSII-H Subunit in Photoprotection: NOVEL ASPECTS OF D1 TURNOVER IN SYNECHOCYSTIS 6803
J. Biol. Chem. 2003 278: 41820-41829. First Published on August 9, 2003; doi:10.1074/jbc.M303096200 [Abstract] [Full Text] [PDF]  

Bettina Hartlieb, Jens Modrof, Elke Mühlberger, Hans-Dieter Klenk, and Stephan Becker

Oligomerization of Ebola Virus VP30 Is Essential for Viral Transcription and Can Be Inhibited by a Synthetic Peptide
J. Biol. Chem. 2003 278: 41830-41836. First Published on August 11, 2003; doi:10.1074/jbc.M307036200 [Abstract] [Full Text] [PDF]  

Marc Froeschke, Michael Basler, Marcus Groettrup, and Bernhard Dobberstein

Long-lived Signal Peptide of Lymphocytic Choriomeningitis Virus Glycoprotein pGP-C
J. Biol. Chem. 2003 278: 41914-41920. First Published on August 12, 2003; doi:10.1074/jbc.M302343200 [Abstract] [Full Text] [PDF] Supplemental Data  

Barton Wicksteed, Cristina Alarcon, Isabelle Briaud, Melissa K. Lingohr, and Christopher J. Rhodes

Glucose-induced Translational Control of Proinsulin Biosynthesis Is Proportional to Preproinsulin mRNA Levels in Islet -Cells but Not Regulated via a Positive Feedback of Secreted Insulin
J. Biol. Chem. 2003 278: 42080-42090. First Published on August 18, 2003; doi:10.1074/jbc.M303509200 [Abstract] [Full Text] [PDF]  

Juan Cadiñanos, Ignacio Varela, Daniel A. Mandel, Walter K. Schmidt, Araceli Díaz-Perales, Carlos López-Otín, and José M. P. Freije

AtFACE-2, a functional Prenylated Protein Protease from Arabidopsis thaliana Related to Mammalian Ras-converting Enzymes
J. Biol. Chem. 2003 278: 42091-42097. First Published on August 19, 2003; doi:10.1074/jbc.M306700200 [Abstract] [Full Text] [PDF]  

Tomoyuki Oe, Jasbir S. Arora, Seon Hwa Lee, and Ian A. Blair

A Novel Lipid Hydroperoxide-derived Cyclic Covalent Modification to Histone H4
J. Biol. Chem. 2003 278: 42098-42105. First Published on August 20, 2003; doi:10.1074/jbc.M308167200 [Abstract] [Full Text] [PDF]  

Junji Watanabe, Yasunari Miyazaki, Guy A. Zimmerman, Kurt H. Albertine, and Thomas M. McIntyre

Endotoxin Contamination of Ovalbumin Suppresses Murine Immunologic Responses and Development of Airway Hyper-reactivity
J. Biol. Chem. 2003 278: 42361-42368. First Published on August 8, 2003; doi:10.1074/jbc.M307752200 [Abstract] [Full Text] [PDF]  

Fiamma Mantovani and Lawrence Banks

Regulation of the Discs Large Tumor Suppressor by a Phosphorylation-dependent Interaction with the -TrCP Ubiquitin Ligase Receptor
J. Biol. Chem. 2003 278: 42477-42486. First Published on August 5, 2003; doi:10.1074/jbc.M302799200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Birke Bartosch, Alessandra Vitelli, Christelle Granier, Caroline Goujon, Jean Dubuisson, Simona Pascale, Elisa Scarselli, Riccardo Cortese, Alfredo Nicosia, and François-Loïc Cosset

Cell Entry of Hepatitis C Virus Requires a Set of Co-receptors That Include the CD81 Tetraspanin and the SR-B1 Scavenger Receptor
J. Biol. Chem. 2003 278: 41624-41630. First Published on August 11, 2003; doi:10.1074/jbc.M305289200 [Abstract] [Full Text] [PDF]  

Gayathri Venkatraman, Keita Harada, Aldrin V. Gomes, W. Glenn L. Kerrick, and James D. Potter

Different Functional Properties of Troponin T Mutants That Cause Dilated Cardiomyopathy
J. Biol. Chem. 2003 278: 41670-41676. First Published on August 14, 2003; doi:10.1074/jbc.M302148200 [Abstract] [Full Text] [PDF]  

Mark J. Heller, Mahta Nili, Earl Homsher, and Larry S. Tobacman

Cardiomyopathic Tropomyosin Mutations That Increase Thin Filament Ca²⁺ Sensitivity and Tropomyosin N-domain Flexibility
J. Biol. Chem. 2003 278: 41742-41748. First Published on August 4, 2003; doi:10.1074/jbc.M303408200 [Abstract] [Full Text] [PDF]  

Barend Bouma, Loes M. J. Kroon-Batenburg, Ya-Ping Wu, Bettina Brünjes, George Posthuma, Onno Kranenburg, Philip G. de Groot, Emile E. Voest, and Martijn F. B. G. Gebbink

Glycation Induces Formation of Amyloid Cross- Structure in Albumin
J. Biol. Chem. 2003 278: 41810-41819. First Published on August 8, 2003; doi:10.1074/jbc.M303925200 [Abstract] [Full Text] [PDF]  

Pantelis Poumbourios, Anne L. Maerz, and Heidi E. Drummer

Functional Evolution of the HIV-1 Envelope Glycoprotein 120 Association Site of Glycoprotein 41
J. Biol. Chem. 2003 278: 42149-42160. First Published on August 15, 2003; doi:10.1074/jbc.M305223200 [Abstract] [Full Text] [PDF]  

Audrey McAlinden, Thomasin A. Smith, Linda J. Sandell, Damien Ficheux, David A. D. Parry, and David J. S. Hulmes

-Helical Coiled-coil Oligomerization Domains Are Almost Ubiquitous in the Collagen Superfamily
J. Biol. Chem. 2003 278: 42200-42207. First Published on August 14, 2003; doi:10.1074/jbc.M302429200 [Abstract] [Full Text] [PDF]  

Seung-Wook Chi, Kyu-Hwan Park, Jae-Eun Suk, Baldomero M. Olivera, J. Michael McIntosh, and Kyou-Hoon Han

Solution Conformation of A-conotoxin EIVA, a Potent Neuromuscular Nicotinic Acetylcholine Receptor Antagonist from Conus ermineus
J. Biol. Chem. 2003 278: 42208-42213. First Published on August 4, 2003; doi:10.1074/jbc.M303342200 [Abstract] [Full Text] [PDF]  

Masamichi Nagae, Akira Nozawa, Nozomu Koizumi, Hiroshi Sano, Hiroshi Hashimoto, Mamoru Sato, and Toshiyuki Shimizu

The Crystal Structure of the Novel Calcium-binding Protein AtCBL2 from Arabidopsis thaliana
J. Biol. Chem. 2003 278: 42240-42246. First Published on July 19, 2003; doi:10.1074/jbc.M303630200 [Abstract] [Full Text] [PDF]  

Stefan Steinbacher, Susanne Schiffmann, Gerald Richter, Robert Huber, Adelbert Bacher, and Markus Fischer

Structure of 3,4-Dihydroxy-2-butanone 4-Phosphate Synthase from Methanococcus jannaschii in Complex with Divalent Metal Ions and the Substrate Ribulose 5-Phosphate: IMPLICATIONS FOR THE CATALYTIC MECHANISM
J. Biol. Chem. 2003 278: 42256-42265. First Published on August 6, 2003; doi:10.1074/jbc.M307301200 [Abstract] [Full Text] [PDF]  

James J. Truglio, Karsten Theis, Yuguo Feng, Ramona Gajda, Carl Machutta, Peter J. Tonge, and Caroline Kisker

Crystal Structure of Mycobacterium tuberculosis MenB, a Key Enzyme in Vitamin K₂ Biosynthesis
J. Biol. Chem. 2003 278: 42352-42360. First Published on August 8, 2003; doi:10.1074/jbc.M307399200 [Abstract] [Full Text] [PDF]  

Wen-Ji Dong, John M. Robinson, Jun Xing, and Herbert C. Cheung

Kinetics of Conformational Transitions in Cardiac Troponin Induced by Ca²⁺ Dissociation Determined by Förster Resonance Energy Transfer
J. Biol. Chem. 2003 278: 42394-42402. First Published on August 9, 2003; doi:10.1074/jbc.M304858200 [Abstract] [Full Text] [PDF]  

Belinda J. Westman, José Perdomo, Margaret Sunde, Merlin Crossley, and Joel P. Mackay

The C-terminal Domain of Eos Forms a High Order Complex in Solution
J. Biol. Chem. 2003 278: 42419-42426. First Published on August 12, 2003; doi:10.1074/jbc.M306817200 [Abstract] [Full Text] [PDF]  

Andreas Schweizer, Christophe Briand, and Markus G. Grütter

Crystal Structure of Caspase-2, Apical Initiator of the Intrinsic Apoptotic Pathway
J. Biol. Chem. 2003 278: 42441-42447. First Published on August 14, 2003; doi:10.1074/jbc.M304895200 [Abstract] [Full Text] [PDF]  

Karin Nienhaus, Pengchi Deng, John S. Olson, Joshua J. Warren, and G. Ulrich Nienhaus

Structural Dynamics of Myoglobin: LIGAND MIGRATION AND BINDING IN VALINE 68 MUTANTS
J. Biol. Chem. 2003 278: 42532-42544. First Published on August 7, 2003; doi:10.1074/jbc.M306888200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Tsuyoshi Egawa, Shiro Yoshioka, Satoshi Takahashi, Hiroshi Hori, Shingo Nagano, Hideo Shimada, Koichiro Ishimori, Isao Morishima, Makoto Suematsu, and Yuzuru Ishimura

Kinetic and Spectroscopic Characterization of a Hydroperoxy Compound in the Reaction of Native Myoglobin with Hydrogen Peroxide
J. Biol. Chem. 2003 278: 41597-41606. First Published on August 5, 2003; doi:10.1074/jbc.M210383200 [Abstract] [Full Text] [PDF]  

Ernst G. Malygin, William M. Lindstrom, Jr., Victor V. Zinoviev, Alexey A. Evdokimov, Samuel L. Schlagman, Norbert O. Reich, and Stanley Hattman

Bacteriophage T4Dam (DNA-(Adenine-N⁶)-methyltransferase): EVIDENCE FOR TWO DISTINCT STAGES OF METHYLATION UNDER SINGLE TURNOVER CONDITIONS
J. Biol. Chem. 2003 278: 41749-41755. First Published on July 30, 2003; doi:10.1074/jbc.M306397200 [Abstract] [Full Text] [PDF]  

Hao Wu and Zhi-Xin Wang

The Mechanism of p21-activated Kinase 2 Autoactivation
J. Biol. Chem. 2003 278: 41768-41778. First Published on August 7, 2003; doi:10.1074/jbc.M308196200 [Abstract] [Full Text] [PDF]  

Sebastiana Angelaccio, Roberta Chiaraluce, Valerio Consalvi, Bärbel Buchenau, Laura Giangiacomo, Francesco Bossa, and Roberto Contestabile

Catalytic and Thermodynamic Properties of Tetrahydromethanopterin-dependent Serine Hydroxymethyltransferase from Methanococcus jannaschii
J. Biol. Chem. 2003 278: 41789-41797. First Published on August 5, 2003; doi:10.1074/jbc.M306747200 [Abstract] [Full Text] [PDF]  

Kai Y. Xu, Shanmuga P. Kuppusamy, Jing Q. Wang, Haiquan Li, Hongmei Cui, Ted M. Dawson, Paul L. Huang, Arthur L. Burnett, Periannan Kuppusamy, and Lewis C. Becker

Nitric Oxide Protects Cardiac Sarcolemmal Membrane Enzyme Function and Ion Active Transport against Ischemia-induced Inactivation
J. Biol. Chem. 2003 278: 41798-41803. First Published on August 6, 2003; doi:10.1074/jbc.M306865200 [Abstract] [Full Text] [PDF]  

Pradeep Bist and Desirazu N. Rao

Identification and Mutational Analysis of Mg²⁺ Binding Site in EcoP15I DNA Methyltransferase: INVOLVEMENT IN TARGET BASE EVERSION
J. Biol. Chem. 2003 278: 41837-41848. First Published on August 12, 2003; doi:10.1074/jbc.M307053200 [Abstract] [Full Text] [PDF]  

Helen K. Leech, Evelyne Raux, Kirsty J. McLean, Andrew W. Munro, Nigel J. Robinson, Gilles P. M. Borrelly, Marco Malten, Dieter Jahn, Stephen E. J. Rigby, Peter Heathcote, and Martin J. Warren

Characterization of the Cobaltochelatase CbiX^L: EVIDENCE FOR A 4Fe-4S CENTER HOUSED WITHIN AN MXCXXC MOTIF
J. Biol. Chem. 2003 278: 41900-41907. First Published on August 12, 2003; doi:10.1074/jbc.M306112200 [Abstract] [Full Text] [PDF]  

Kenji Watanabe, Clay C. C. Wang, Christopher N. Boddy, David E. Cane, and Chaitan Khosla

Understanding Substrate Specificity of Polyketide Synthase Modules by Generating Hybrid Multimodular Synthases
J. Biol. Chem. 2003 278: 42020-42026. First Published on August 15, 2003; doi:10.1074/jbc.M305339200 [Abstract] [Full Text] [PDF]  

Rong Zhang, Hae Yun Cho, Hyun Sic Kim, Young Gerl Ma, Tsukasa Osaki, Shun-ichiro Kawabata, Kenneth Söderhäll, and Bok Luel Lee

Characterization and Properties of a 1,3--D-Glucan Pattern Recognition Protein of Tenebrio molitor Larvae That Is Specifically Degraded by Serine Protease during Prophenoloxidase Activation
J. Biol. Chem. 2003 278: 42072-42079. First Published on August 15, 2003; doi:10.1074/jbc.M307475200 [Abstract] [Full Text] [PDF]  

Francesca De Maria, Jens Z. Pedersen, Anna Maria Caccuri, Giovanni Antonini, Paola Turella, Lorenzo Stella, Mario Lo Bello, Giorgio Federici, and Giorgio Ricci

The Specific Interaction of Dinitrosyl-Diglutathionyl-Iron Complex, a Natural NO Carrier, with the Glutathione Transferase Superfamily: SUGGESTION FOR AN EVOLUTIONARY PRESSURE IN THE DIRECTION OF THE STORAGE OF NITRIC OXIDE
J. Biol. Chem. 2003 278: 42283-42293. First Published on July 18, 2003; doi:10.1074/jbc.M305568200 [Abstract] [Full Text] [PDF]  

Paola Turella, Jens Z. Pedersen, Anna Maria Caccuri, Francesca De Maria, Piergiorgio Mastroberardino, Mario Lo Bello, Giorgio Federici, and Giorgio Ricci

Glutathione Transferase Superfamily Behaves Like Storage Proteins for Dinitrosyl-Diglutathionyl-Iron Complex in Heterogeneous Systems
J. Biol. Chem. 2003 278: 42294-42299. First Published on July 18, 2003; doi:10.1074/jbc.M305569200 [Abstract] [Full Text] [PDF]  

Jeffrey D. Kittendorf, Tanja Sgraja, Klaus Reuter, Gerhard Klebe, and George A. Garcia

An Essential Role for Aspartate 264 in Catalysis by tRNA-Guanine Transglycosylase from Escherichia coli
J. Biol. Chem. 2003 278: 42369-42376. First Published on August 8, 2003; doi:10.1074/jbc.M304323200 [Abstract] [Full Text] [PDF]  

Yuko Wada, Hitoshi Ohya, Yube Yamaguchi, Nozomu Koizumi, and Hiroshi Sano

Preferential de Novo Methylation of Cytosine Residues in Non-CpG Sequences by a Domains Rearranged DNA Methyltransferase from Tobacco Plants
J. Biol. Chem. 2003 278: 42386-42393. First Published on August 12, 2003; doi:10.1074/jbc.M303892200 [Abstract] [Full Text] [PDF]  

James P. Villa, Greg P. Bertenshaw, and Judith S. Bond

Critical Amino Acids in the Active Site of Meprin Metalloproteinases for Substrate and Peptide Bond Specificity
J. Biol. Chem. 2003 278: 42545-42550. First Published on July 29, 2003; doi:10.1074/jbc.M303718200 [Abstract] [Full Text] [PDF]  

Tahir M. Razzaq, Rosemary Bass, David J. Vines, Finn Werner, Simon A. Whawell, and Vincent Ellis

Functional Regulation of Tissue Plasminogen Activator on the Surface of Vascular Smooth Muscle Cells by the Type-II Transmembrane Protein p63 (CKAP4)
J. Biol. Chem. 2003 278: 42679-42685. First Published on August 11, 2003; doi:10.1074/jbc.M305695200 [Abstract] [Full Text] [PDF] Supplemental Data  

Metabolism and Bioenergetics:

Laran T. Jensen, Mispa Ajua-Alemanji, and Valeria Cizewski Culotta

The Saccharomyces cerevisiae High Affinity Phosphate Transporter Encoded by PHO84 Also Functions in Manganese Homeostasis
J. Biol. Chem. 2003 278: 42036-42040. First Published on August 15, 2003; doi:10.1074/jbc.M307413200 [Abstract] [Full Text] [PDF]  

Marie-Clotilde Alves-Guerra, Sophie Rousset, Claire Pecqueur, Ziad Mallat, Julie Blanc, Alain Tedgui, Fredéric Bouillaud, Anne-Marie Cassard-Doulcier, Daniel Ricquier, and Bruno Miroux

Bone Marrow Transplantation Reveals the in Vivo Expression of the Mitochondrial Uncoupling Protein 2 in Immune and Nonimmune Cells during Inflammation
J. Biol. Chem. 2003 278: 42307-42312. First Published on August 7, 2003; doi:10.1074/jbc.M306951200 [Abstract] [Full Text] [PDF]  

Aurelio Garofano, Klaus Zwicker, Stefan Kerscher, Pamela Okun, and Ulrich Brandt

Two Aspartic Acid Residues in the PSST-Homologous NUKM Subunit of Complex I from Yarrowia lipolytica Are Essential for Catalytic Activity
J. Biol. Chem. 2003 278: 42435-42440. First Published on August 20, 2003; doi:10.1074/jbc.M305819200 [Abstract] [Full Text] [PDF]  

Julia L. Brumaghim, Ying Li, Ernst Henle, and Stuart Linn

Effects of Hydrogen Peroxide upon Nicotinamide Nucleotide Metabolism in Escherichia coli: CHANGES IN ENZYME LEVELS AND NICOTINAMIDE NUCLEOTIDE POOLS AND STUDIES OF THE OXIDATION OF NAD(P)H BY Fe(III)
J. Biol. Chem. 2003 278: 42495-42504. First Published on August 11, 2003; doi:10.1074/jbc.M306251200 [Abstract] [Full Text] [PDF] Supplemental Data  

Anna Pastore, Giulia Tozzi, Laura Maria Gaeta, Enrico Bertini, Valentina Serafini, Silvia Di Cesare, Valentina Bonetto, Filippo Casoni, Rosalba Carrozzo, Giorgio Federici, and Fiorella Piemonte

Actin Glutathionylation Increases in Fibroblasts of Patients with Friedreich's Ataxia: A POTENTIAL ROLE IN THE PATHOGENESIS OF THE DISEASE
J. Biol. Chem. 2003 278: 42588-42595. First Published on August 11, 2003; doi:10.1074/jbc.M301872200 [Abstract] [Full Text] [PDF]  

Ken Yokoyama, Koji Nagata, Hiromi Imamura, Shoji Ohkuma, Masasuke Yoshida, and Masatada Tamakoshi

Subunit Arrangement in V-ATPase from Thermus thermophilus
J. Biol. Chem. 2003 278: 42686-42691. First Published on August 11, 2003; doi:10.1074/jbc.M305853200 [Abstract] [Full Text] [PDF]  

Masaharu Tokoro, Takashi Asai, Seiki Kobayashi, Tsutomu Takeuchi, and Tomoyoshi Nozaki

Identification and Characterization of Two Isoenzymes of Methionine -Lyase from Entamoeba histolytica: A KEY ENZYME OF SULFUR-AMINO ACID DEGRADATION IN AN ANAEROBIC PARASITIC PROTIST THAT LACKS FORWARD AND REVERSE TRANS-SULFURATION PATHWAYS
J. Biol. Chem. 2003 278: 42717-42727. First Published on August 14, 2003; doi:10.1074/jbc.M212414200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Byung-Taek Kim, Hiroshi Kitagawa, Junko Tanaka, Jun-ichi Tamura, and Kazuyuki Sugahara

In Vitro Heparan Sulfate Polymerization: CRUCIAL ROLES OF CORE PROTEIN MOIETIES OF PRIMER SUBSTRATES IN ADDITION TO THE EXT1-EXT2 INTERACTION
J. Biol. Chem. 2003 278: 41618-41623. First Published on August 7, 2003; doi:10.1074/jbc.M304831200 [Abstract] [Full Text] [PDF]  

Eri Maehashi, Chihiro Sato, Kaoru Ohta, Yoichiro Harada, Tsukasa Matsuda, Noritaka Hirohashi, William J. Lennarz, and Ken Kitajima

Identification of the Sea Urchin 350-kDa Sperm-binding Protein as a New Sialic Acid-binding Lectin That Belongs to the Heat Shock Protein 110 Family: IMPLICATION OF ITS BINDING TO GANGLIOSIDES IN SPERM LIPID RAFTS IN FERTILIZATION
J. Biol. Chem. 2003 278: 42050-42057. First Published on August 12, 2003; doi:10.1074/jbc.M307493200 [Abstract] [Full Text] [PDF]  

Darryl L. Russell, Kari M. H. Doyle, Scott A. Ochsner, John D. Sandy, and JoAnne S. Richards

Processing and Localization of ADAMTS-1 and Proteolytic Cleavage of Versican during Cumulus Matrix Expansion and Ovulation
J. Biol. Chem. 2003 278: 42330-42339. First Published on August 7, 2003; doi:10.1074/jbc.M300519200 [Abstract] [Full Text] [PDF]  

Tetsuya Okajima, Aiguo Xu, and Kenneth D. Irvine

Modulation of Notch-Ligand Binding by Protein O-Fucosyltransferase 1 and Fringe
J. Biol. Chem. 2003 278: 42340-42345. First Published on August 8, 2003; doi:10.1074/jbc.M308687200 [Abstract] [Full Text] [PDF]  

Elisabetta A. M. Verderio, Dilek Telci, Afam Okoye, Gerry Melino, and Martin Griffin

A Novel RGD-independent Cell Adhesion Pathway Mediated by Fibronectin-bound Tissue Transglutaminase Rescues Cells from Anoikis
J. Biol. Chem. 2003 278: 42604-42614. First Published on May 5, 2003; doi:10.1074/jbc.M303303200 [Abstract] [Full Text] [PDF] Supplemental Data  

Lipids and Lipoproteins:

Mitsuru Ono, Tetsuya Shimizugawa, Mitsuru Shimamura, Kenichi Yoshida, Chisa Noji-Sakikawa, Yosuke Ando, Ryuta Koishi, and Hidehiko Furukawa

Protein Region Important for Regulation of Lipid Metabolism in Angiopoietin-like 3 (ANGPTL3): ANGPTL3 IS CLEAVED AND ACTIVATED IN VIVO
J. Biol. Chem. 2003 278: 41804-41809. First Published on August 8, 2003; doi:10.1074/jbc.M302861200 [Abstract] [Full Text] [PDF]  

Sook-Jae Seo, Hyang-Mi Cheon, Jianxin Sun, Thomas W. Sappington, and Alexander S. Raikhel

Tissue- and Stage-specific Expression of Two Lipophorin Receptor Variants with Seven and Eight Ligand-binding Repeats in the Adult Mosquito
J. Biol. Chem. 2003 278: 41954-41962. First Published on August 13, 2003; doi:10.1074/jbc.M308200200 [Abstract] [Full Text] [PDF]  

Thomas O. Metz, Nathan L. Alderson, Mark E. Chachich, Suzanne R. Thorpe, and John W. Baynes

Pyridoxamine Traps Intermediates in Lipid Peroxidation Reactions in Vivo: EVIDENCE ON THE ROLE OF LIPIDS IN CHEMICAL MODIFICATION OF PROTEIN AND DEVELOPMENT OF DIABETIC COMPLICATIONS
J. Biol. Chem. 2003 278: 42012-42019. First Published on August 15, 2003; doi:10.1074/jbc.M304292200 [Abstract] [Full Text] [PDF]  

Xiaorong Gu, Susan Gillette Meer, Masaru Miyagi, Mary E. Rayborn, Joe G. Hollyfield, John W. Crabb, and Robert G. Salomon

Carboxyethylpyrrole Protein Adducts and Autoantibodies, Biomarkers for Age-related Macular Degeneration
J. Biol. Chem. 2003 278: 42027-42035. First Published on August 15, 2003; doi:10.1074/jbc.M305460200 [Abstract] [Full Text] [PDF] Supplemental Data  

Junji Yamaguchi, Mary V. Gamble, Donna Conlon, Jun-shan Liang, and Henry N. Ginsberg

The Conversion of ApoB100 Low Density Lipoprotein/High Density Lipoprotein Particles to ApoB100 Very Low Density Lipoproteins in Response to Oleic Acid Occurs in the Endoplasmic Reticulum and Not in the Golgi in McA RH7777 Cells
J. Biol. Chem. 2003 278: 42643-42651. First Published on August 12, 2003; doi:10.1074/jbc.M306920200 [Abstract] [Full Text] [PDF]  

Osamu Kuge, Kazuhide Hasegawa, Tomoko Ohsawa, Kyoko Saito, and Masahiro Nishijima

Purification and Characterization of Chinese Hamster Phosphatidylserine Synthase 2
J. Biol. Chem. 2003 278: 42692-42698. First Published on August 11, 2003; doi:10.1074/jbc.M307270200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Leopoldo de Meis

Brown Adipose Tissue Ca²⁺-ATPase: UNCOUPLED ATP HYDROLYSIS AND THERMOGENIC ACTIVITY
J. Biol. Chem. 2003 278: 41856-41861. First Published on August 11, 2003; doi:10.1074/jbc.M308280200 [Abstract] [Full Text] [PDF]  

Shoko Kawasaki-Nishi, Tsuyoshi Nishi, and Michael Forgac

Interacting Helical Surfaces of the Transmembrane Segments of Subunits a and c' of the Yeast V-ATPase Defined by Disulfide-mediated Cross-linking
J. Biol. Chem. 2003 278: 41908-41913. First Published on August 12, 2003; doi:10.1074/jbc.M308026200 [Abstract] [Full Text] [PDF]  

Tineke Kok, Christian V. Hulzebos, Henk Wolters, Rick Havinga, Luis B. Agellon, Frans Stellaard, Bei Shan, Margrit Schwarz, and Folkert Kuipers

Enterohepatic Circulation of Bile Salts in Farnesoid X Receptor-deficient Mice: EFFICIENT INTESTINAL BILE SALT ABSORPTION IN THE ABSENCE OF ILEAL BILE ACID-BINDING PROTEIN
J. Biol. Chem. 2003 278: 41930-41937. First Published on August 12, 2003; doi:10.1074/jbc.M306309200 [Abstract] [Full Text] [PDF]  

Sara W. Leung, Michelle T. Harreman, Mary R. Hodel, Alec E. Hodel, and Anita H. Corbett

Dissection of the Karyopherin Nuclear Localization Signal (NLS)-binding Groove: FUNCTIONAL REQUIREMENTS FOR NLS BINDING
J. Biol. Chem. 2003 278: 41947-41953. First Published on August 13, 2003; doi:10.1074/jbc.M307162200 [Abstract] [Full Text] [PDF]  

Thomas Waizenegger, Tincuta Stan, Walter Neupert, and Doron Rapaport

Signal-Anchor Domains of Proteins of the Outer Membrane of Mitochondria: STRUCTURAL AND FUNCTIONAL CHARACTERISTICS
J. Biol. Chem. 2003 278: 42064-42071. First Published on August 13, 2003; doi:10.1074/jbc.M305736200 [Abstract] [Full Text] [PDF]  

Allan M. Torres, Paramjit S. Bansal, Margaret Sunde, Catherine E. Clarke, Jane A. Bursill, David J. Smith, Asne Bauskin, Samuel N. Breit, Terence J. Campbell, Paul F. Alewood, Philip W. Kuchel, and Jamie I. Vandenberg

Structure of the HERG K⁺ Channel S5P Extracellular Linker: ROLE OF AN AMPHIPATHIC -HELIX IN C-TYPE INACTIVATION
J. Biol. Chem. 2003 278: 42136-42148. First Published on August 5, 2003; doi:10.1074/jbc.M212824200 [Abstract] [Full Text] [PDF] Supplemental Data  

Anja T. Fuglsang, Jonas Borch, Katrine Bych, Thomas P. Jahn, Peter Roepstorff, and Michael G. Palmgren

The Binding Site for Regulatory 14-3-3 Protein in Plant Plasma Membrane H⁺-ATPase: INVOLVEMENT OF A REGION PROMOTING PHOSPHORYLATION-INDEPENDENT INTERACTION IN ADDITION TO THE PHOSPHORYLATION-DEPENDENT C-TERMINAL END
J. Biol. Chem. 2003 278: 42266-42272. First Published on July 29, 2003; doi:10.1074/jbc.M306707200 [Abstract] [Full Text] [PDF]  

Laura Zannini, Daniele Lecis, Sofia Lisanti, Roberta Benetti, Giacomo Buscemi, Claudio Schneider, and Domenico Delia

Karyopherin-2 Protein Interacts with Chk2 and Contributes to Its Nuclear Import
J. Biol. Chem. 2003 278: 42346-42351. First Published on August 9, 2003; doi:10.1074/jbc.M303304200 [Abstract] [Full Text] [PDF]  

Irina A. Ignatovich, Ella B. Dizhe, Anna V. Pavlotskaya, Boris N. Akifiev, Sergey V. Burov, Sergey V. Orlov, and Andrej P. Perevozchikov

Complexes of Plasmid DNA with Basic Domain 47-57 of the HIV-1 Tat Protein Are Transferred to Mammalian Cells by Endocytosis-mediated Pathways
J. Biol. Chem. 2003 278: 42625-42636. First Published on July 25, 2003; doi:10.1074/jbc.M301431200 [Abstract] [Full Text] [PDF]  

Brook Pyhtila and Michael Rexach

A Gradient of Affinity for the Karyopherin Kap95p along the Yeast Nuclear Pore Complex
J. Biol. Chem. 2003 278: 42699-42709. First Published on August 12, 2003; doi:10.1074/jbc.M307135200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Xiaowu Li, Yongjian Yang, Yongmei Hu, Dongmin Dang, Joseph Regezi, Brian L. Schmidt, Amha Atakilit, Bing Chen, Duncan Ellis, and Daniel M. Ramos

_v6-Fyn Signaling Promotes Oral Cancer Progression
J. Biol. Chem. 2003 278: 41646-41653. First Published on August 12, 2003; doi:10.1074/jbc.M306274200 [Abstract] [Full Text] [PDF]  

Shin-ichi Yokota, Noriko Yokosawa, Toru Kubota, Tamaki Okabayashi, Satoru Arata, and Nobuhiro Fujii

Suppression of Thermotolerance in Mumps Virus-infected Cells Is Caused by Lack of HSP27 Induction Contributed by STAT-1
J. Biol. Chem. 2003 278: 41654-41660. First Published on August 13, 2003; doi:10.1074/jbc.M305701200 [Abstract] [Full Text] [PDF]  

De Pradip, Xiaodong Peng, and Donald L. Durden

Rac2 Specificity in Macrophage Integrin Signaling: POTENTIAL ROLE FOR Syk KINASE
J. Biol. Chem. 2003 278: 41661-41669. First Published on August 12, 2003; doi:10.1074/jbc.M306491200 [Abstract] [Full Text] [PDF]  

Toshiyuki Araki, Hiroyuki Nawa, and Benjamin G. Neel

Tyrosyl Phosphorylation of Shp2 Is Required for Normal ERK Activation in Response to Some, but Not All, Growth Factors
J. Biol. Chem. 2003 278: 41677-41684. First Published on August 14, 2003; doi:10.1074/jbc.M306461200 [Abstract] [Full Text] [PDF]  

Alexandra Krauskopf, Philippe Lhote, Manfred Mutter, Jean-François Dufour, Urs T. Ruegg, and Timo M. Buetler

Vasopressin Type 1A Receptor Up-regulation by Cyclosporin A in Vascular Smooth Muscle Cells Is Mediated by Superoxide
J. Biol. Chem. 2003 278: 41685-41690. First Published on August 17, 2003; doi:10.1074/jbc.M301181200 [Abstract] [Full Text] [PDF]  

Stephen E. Girardin, Leonardo H. Travassos, Mireille Hervé, Didier Blanot, Ivo G. Boneca, Dana J. Philpott, Philippe J. Sansonetti, and Dominique Mengin-Lecreulx

Peptidoglycan Molecular Requirements Allowing Detection by Nod1 and Nod2
J. Biol. Chem. 2003 278: 41702-41708. First Published on July 18, 2003; doi:10.1074/jbc.M307198200 [Abstract] [Full Text] [PDF]  

Qishen Pang, Tracy A. Christianson, Tara Koretsky, Hanqian Carlson, Larry David, Winifred Keeble, Gregory R. Faulkner, Ashley Speckhart, and Grover C. Bagby

Nucleophosmin Interacts with and Inhibits the Catalytic Function of Eukaryotic Initiation Factor 2 Kinase PKR
J. Biol. Chem. 2003 278: 41709-41717. First Published on July 25, 2003; doi:10.1074/jbc.M301392200 [Abstract] [Full Text] [PDF]  

James J. Fiordalisi, Ronald L. Johnson, II, Carolyn A. Weinbaum, Kaoru Sakabe, Zhui Chen, Patrick J. Casey, and Adrienne D. Cox

High Affinity for Farnesyltransferase and Alternative Prenylation Contribute Individually to K-Ras4B Resistance to Farnesyltransferase Inhibitors
J. Biol. Chem. 2003 278: 41718-41727. First Published on July 25, 2003; doi:10.1074/jbc.M305733200 [Abstract] [Full Text] [PDF]  

Fubo Liang, Zhonghui Huang, Seung-Yub Lee, Jiao Liang, Maya I. Ivanov, Andres Alonso, James B. Bliska, David S. Lawrence, Tomas Mustelin, and Zhong-Yin Zhang

Aurintricarboxylic Acid Blocks in Vitro and in Vivo Activity of YopH, an Essential Virulent Factor of Yersinia pestis, the Agent of Plague
J. Biol. Chem. 2003 278: 41734-41741. First Published on July 29, 2003; doi:10.1074/jbc.M307152200 [Abstract] [Full Text] [PDF]  

Sherri L. Christian, Rosaline L. Lee, Sarah J. McLeod, Anita E. Burgess, Anson H. Y. Li, May Dang-Lawson, Kevin B. L. Lin, and Michael R. Gold

Activation of the Rap GTPases in B Lymphocytes Modulates B Cell Antigen Receptor-induced Activation of Akt but Has No Effect on MAPK Activation
J. Biol. Chem. 2003 278: 41756-41767. First Published on August 6, 2003; doi:10.1074/jbc.M303180200 [Abstract] [Full Text] [PDF]  

Gangyong Li, Shengfu Wang, and Thomas D. Gelehrter

Identification of Glucocorticoid Receptor Domains Involved in Transrepression of Transforming Growth Factor- Action
J. Biol. Chem. 2003 278: 41779-41788. First Published on August 5, 2003; doi:10.1074/jbc.M305350200 [Abstract] [Full Text] [PDF]  

Nazif Alic, Vincent J. Higgins, Alena Pichova, Michael Breitenbach, and Ian W. Dawes

Lipid Hydroperoxides Activate the Mitogen-activated Protein Kinase Mpk1p in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 41849-41855. First Published on August 11, 2003; doi:10.1074/jbc.M307760200 [Abstract] [Full Text] [PDF] Supplemental Data  

Subburaj Ilangumaran, Dina Finan, Jason Raine, and Robert Rottapel

Suppressor of Cytokine Signaling 1 Regulates an Endogenous Inhibitor of a Mast Cell Protease
J. Biol. Chem. 2003 278: 41871-41880. First Published on August 12, 2003; doi:10.1074/jbc.M308382200 [Abstract] [Full Text] [PDF]  

George R. Beck, Jr. and Nicole Knecht

Osteopontin Regulation by Inorganic Phosphate Is ERK1/2-, Protein Kinase C-, and Proteasome-dependent
J. Biol. Chem. 2003 278: 41921-41929. First Published on August 13, 2003; doi:10.1074/jbc.M304470200 [Abstract] [Full Text] [PDF]  

Tien-Shun Yeh, Yu-Min Lin, Rong-Hong Hsieh, and Min-Jen Tseng

Association of Transcription Factor YY1 with the High Molecular Weight Notch Complex Suppresses the Transactivation Activity of Notch
J. Biol. Chem. 2003 278: 41963-41969. First Published on August 11, 2003; doi:10.1074/jbc.M304353200 [Abstract] [Full Text] [PDF]  

Sandrine Horman, Christophe Beauloye, Didier Vertommen, Jean-Louis Vanoverschelde, Louis Hue, and Mark H. Rider

Myocardial Ischemia and Increased Heart Work Modulate the Phosphorylation State of Eukaryotic Elongation Factor-2
J. Biol. Chem. 2003 278: 41970-41976. First Published on August 14, 2003; doi:10.1074/jbc.M302403200 [Abstract] [Full Text] [PDF]  

Laura J. Sampson, Mark L. Leyland, and Caroline Dart

Direct Interaction between the Actin-binding Protein Filamin-A and the Inwardly Rectifying Potassium Channel, Kir2.1
J. Biol. Chem. 2003 278: 41988-41997. First Published on August 14, 2003; doi:10.1074/jbc.M307479200 [Abstract] [Full Text] [PDF]  

Xiuhai Ren and Istvan Mody

-Hydroxybutyrate Reduces Mitogen-activated Protein Kinase Phosphorylation via GABA_B Receptor Activation in Mouse Frontal Cortex and Hippocampus
J. Biol. Chem. 2003 278: 42006-42011. First Published on August 15, 2003; doi:10.1074/jbc.M304238200 [Abstract] [Full Text] [PDF]  

Meir H. Scheinfeld, Enrico Ghersi, Peter Davies, and Luciano D'Adamio

Amyloid Protein Precursor Is Phosphorylated by JNK-1 Independent of, yet Facilitated by, JNK-Interacting Protein (JIP)-1
J. Biol. Chem. 2003 278: 42058-42063. First Published on August 13, 2003; doi:10.1074/jbc.M304853200 [Abstract] [Full Text] [PDF]  

Teresa M. Kubiak, Martha J. Larsen, Marjorie R. Zantello, Jerry W. Bowman, Susan C. Nulf, and David E. Lowery

Functional Annotation of the Putative Orphan Caenorhabditis elegans G-protein-coupled Receptor C10C6.2 as a FLP15 Peptide Receptor
J. Biol. Chem. 2003 278: 42115-42120. First Published on August 22, 2003; doi:10.1074/jbc.M304056200 [Abstract] [Full Text] [PDF]  

Lea Madi, Sara Bar-Yehuda, Faina Barer, Eti Ardon, Avivit Ochaion, and Pnina Fishman

A3 Adenosine Receptor Activation in Melanoma Cells: ASSOCIATION BETWEEN RECEPTOR FATE AND TUMOR GROWTH INHIBITION
J. Biol. Chem. 2003 278: 42121-42130. First Published on July 15, 2003; doi:10.1074/jbc.M301243200 [Abstract] [Full Text] [PDF]  

Kwang-Mook Jung, Serena Tan, Natalie Landman, Kseniya Petrova, Simon Murray, Renee Lewis, Peter K. Kim, Dae Sup Kim, Sung Ho Ryu, Moses V. Chao, and Tae-Wan Kim

Regulated Intramembrane Proteolysis of the p75 Neurotrophin Receptor Modulates Its Association with the TrkA Receptor
J. Biol. Chem. 2003 278: 42161-42169. First Published on August 11, 2003; doi:10.1074/jbc.M306028200 [Abstract] [Full Text] [PDF]  

Giuseppe Pandini, Enzo Medico, Enrico Conte, Laura Sciacca, Riccardo Vigneri, and Antonino Belfiore

Differential Gene Expression Induced by Insulin and Insulin-like Growth Factor-II through the Insulin Receptor Isoform A
J. Biol. Chem. 2003 278: 42178-42189. First Published on July 24, 2003; doi:10.1074/jbc.M304980200 [Abstract] [Full Text] [PDF]  

Sundaravadivel Balasubramanian and Dhandapani Kuppuswamy

RGD-containing Peptides Activate S6K1 through ₃ Integrin in Adult Cardiac Muscle Cells
J. Biol. Chem. 2003 278: 42214-42224. First Published on August 9, 2003; doi:10.1074/jbc.M303428200 [Abstract] [Full Text] [PDF]  

Tetsuya Takahashi, Hiroshi Yamashita, Yoshito Nagano, Takeshi Nakamura, Hiromitsu Ohmori, Hava Avraham, Shalom Avraham, Mineo Yasuda, and Masayasu Matsumoto

Identification and Characterization of a Novel Pyk2/Related Adhesion Focal Tyrosine Kinase-associated Protein That Inhibits -Synuclein Phosphorylation
J. Biol. Chem. 2003 278: 42225-42233. First Published on July 31, 2003; doi:10.1074/jbc.M213217200 [Abstract] [Full Text] [PDF]  

György Csordás and György Hajnóczky

Plasticity of Mitochondrial Calcium Signaling
J. Biol. Chem. 2003 278: 42273-42282. First Published on August 7, 2003; doi:10.1074/jbc.M305248200 [Abstract] [Full Text] [PDF]  

Yong-Xing Zhou, Mingrui Zhao, Dan Li, Kazuhiro Shimazu, Kazuko Sakata, Chu-Xia Deng, and Bai Lu

Cerebellar Deficits and Hyperactivity in Mice Lacking Smad4
J. Biol. Chem. 2003 278: 42313-42320. First Published on August 1, 2003; doi:10.1074/jbc.M308287200 [Abstract] [Full Text] [PDF]  

Jill Hemish, Naoki Nakaya, Vivek Mittal, and Grigori Enikolopov

Nitric Oxide Activates Diverse Signaling Pathways to Regulate Gene Expression
J. Biol. Chem. 2003 278: 42321-42329. First Published on August 7, 2003; doi:10.1074/jbc.M308192200 [Abstract] [Full Text] [PDF] Supplemental Data  

Armelle Calipel, Gaelle Lefevre, Celio Pouponnot, Frédéric Mouriaux, Alain Eychène, and Frédéric Mascarelli

Mutation of B-Raf in Human Choroidal Melanoma Cells Mediates Cell Proliferation and Transformation through the MEK/ERK Pathway
J. Biol. Chem. 2003 278: 42409-42418. First Published on August 12, 2003; doi:10.1074/jbc.M308709200 [Abstract] [Full Text] [PDF]  

Haidong Li, Linda M. Ayer, Jonathan Lytton, and Julie P. Deans

Store-operated Cation Entry Mediated by CD20 in Membrane Rafts
J. Biol. Chem. 2003 278: 42427-42434. First Published on August 14, 2003; doi:10.1074/jbc.M308802200 [Abstract] [Full Text] [PDF]  

Song-Ja Kim, Sang-Gu Hwang, Il-Chul Kim, and Jang-Soo Chun

Actin Cytoskeletal Architecture Regulates Nitric Oxide-induced Apoptosis, Dedifferentiation, and Cyclooxygenase-2 Expression in Articular Chondrocytes via Mitogen-activated Protein Kinase and Protein Kinase C Pathways
J. Biol. Chem. 2003 278: 42448-42456. First Published on August 7, 2003; doi:10.1074/jbc.M304887200 [Abstract] [Full Text] [PDF]  

Yu-Ying He, Jian-Li Huang, Jennifer B. Gentry, and Colin F. Chignell

Epidermal Growth Factor Receptor Down-regulation Induced by UVA in Human Keratinocytes Does Not Require the Receptor Kinase Activity
J. Biol. Chem. 2003 278: 42457-42465. First Published on August 20, 2003; doi:10.1074/jbc.M303376200 [Abstract] [Full Text] [PDF]  

Dmitri Lim, Emanuela Ercolano, Keiichiro Kyozuka, Gilda A. Nusco, Francesco Moccia, Klaus Lange, and Luigia Santella

The M-phase-promoting Factor Modulates the Sensitivity of the Ca²⁺ Stores to Inositol 1,4,5-Trisphosphate via the Actin Cytoskeleton
J. Biol. Chem. 2003 278: 42505-42514. First Published on July 16, 2003; doi:10.1074/jbc.M301851200 [Abstract] [Full Text] [PDF]  

Shiro Suetsugu and Tadaomi Takenawa

Translocation of N-WASP by Nuclear Localization and Export Signals into the Nucleus Modulates Expression of HSP90
J. Biol. Chem. 2003 278: 42515-42523. First Published on July 18, 2003; doi:10.1074/jbc.M302177200 [Abstract] [Full Text] [PDF]  

Franziska Agerer, Antje Michel, Knut Ohlsen, and Christof R. Hauck

Integrin-mediated Invasion of Staphylococcus aureus into Human Cells Requires Src Family Protein-tyrosine Kinases
J. Biol. Chem. 2003 278: 42524-42531. First Published on July 31, 2003; doi:10.1074/jbc.M302096200 [Abstract] [Full Text] [PDF]  

Donghui Kuang, Yi Yao, Minghua Wang, N. Pattabiraman, Lakshmi P. Kotra, and David R. Hampson

Molecular Similarities in the Ligand Binding Pockets of an Odorant Receptor and the Metabotropic Glutamate Receptors
J. Biol. Chem. 2003 278: 42551-42559. First Published on August 11, 2003; doi:10.1074/jbc.M307120200 [Abstract] [Full Text] [PDF]  

Lan Xu, Claudio Alarcón, Seda Çöl, and Joan Massaguè

Distinct Domain Utilization by Smad3 and Smad4 for Nucleoporin Interaction and Nuclear Import
J. Biol. Chem. 2003 278: 42569-42577. First Published on August 13, 2003; doi:10.1074/jbc.M307601200 [Abstract] [Full Text] [PDF]  

Juan J. Carrillo, John Pediani, and Graeme Milligan

Dimers of Class A G Protein-coupled Receptors Function via Agonist-mediated Trans-activation of Associated G Proteins
J. Biol. Chem. 2003 278: 42578-42587. First Published on August 14, 2003; doi:10.1074/jbc.M306165200 [Abstract] [Full Text] [PDF]  

Nupam P. Mahajan and H. Shelton Earp

An SH2 Domain-dependent, Phosphotyrosine-independent Interaction between Vav1 and the Mer Receptor Tyrosine Kinase: A MECHANISM FOR LOCALIZING GUANINE NUCLEOTIDE-EXCHANGE FACTOR ACTION
J. Biol. Chem. 2003 278: 42596-42603. First Published on August 14, 2003; doi:10.1074/jbc.M305817200 [Abstract] [Full Text] [PDF]  

Catherine Julien, Philippe Coulombe, and Sylvain Meloche

Nuclear Export of ERK3 by a CRM1-dependent Mechanism Regulates Its Inhibitory Action on Cell Cycle Progression
J. Biol. Chem. 2003 278: 42615-42624. First Published on August 12, 2003; doi:10.1074/jbc.M302724200 [Abstract] [Full Text] [PDF]  

Michiko Onuma, Jeffrey D. Bub, Thomas L. Rummel, and Yoshiki Iwamoto

Prostate Cancer Cell-Adipocyte Interaction: LEPTIN MEDIATES ANDROGEN-INDEPENDENT PROSTATE CANCER CELL PROLIFERATION THROUGH c-Jun NH₂-TERMINAL KINASE
J. Biol. Chem. 2003 278: 42660-42667. First Published on August 5, 2003; doi:10.1074/jbc.M304984200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Alaric A. Falcón and John P. Aris

Plasmid Accumulation Reduces Life Span in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 41607-41617. First Published on August 6, 2003; doi:10.1074/jbc.M307025200 [Abstract] [Full Text] [PDF]  

Kenji Seki, Toshihiko Fujimori, Pierre Savagner, Akiko Hata, Tomonao Aikawa, Naoshi Ogata, Yoichi Nabeshima, and Lee Kaechoong

Mouse Snail Family Transcription Repressors Regulate Chondrocyte, Extracellular Matrix, Type II Collagen, and Aggrecan
J. Biol. Chem. 2003 278: 41862-41870. First Published on August 12, 2003; doi:10.1074/jbc.M308336200 [Abstract] [Full Text] [PDF]  

Scott Vuocolo, Enkhtsetseg Purev, Dongmei Zhang, Jiri Bartek, Klaus Hansen, Dianne Robert Soprano, and Kenneth J. Soprano

Protein Phosphatase 2A Associates with Rb2/p130 and Mediates Retinoic Acid-induced Growth Suppression of Ovarian Carcinoma Cells
J. Biol. Chem. 2003 278: 41881-41889. First Published on August 12, 2003; doi:10.1074/jbc.M302715200 [Abstract] [Full Text] [PDF]  

Se Jung Kim, Jee Young Sung, Ji Won Um, Nobutaka Hattori, Yoshikuni Mizuno, Keiji Tanaka, Seung R. Paik, Jongsun Kim, and Kwang Chul Chung

Parkin Cleaves Intracellular -Synuclein Inclusions via the Activation of Calpain
J. Biol. Chem. 2003 278: 41890-41899. First Published on August 12, 2003; doi:10.1074/jbc.M306017200 [Abstract] [Full Text] [PDF]  

Cinthya A. Guimarães, Marlene Benchimol, Gustavo P. Amarante-Mendes, and Rafael Linden

Alternative Programs of Cell Death in Developing Retinal Tissue
J. Biol. Chem. 2003 278: 41938-41946. First Published on August 12, 2003; doi:10.1074/jbc.M306547200 [Abstract] [Full Text] [PDF]  

Caroline Düringer, Ali Hamiche, Lotta Gustafsson, Hiroshi Kimura, and Catharina Svanborg

HAMLET Interacts with Histones and Chromatin in Tumor Cell Nuclei
J. Biol. Chem. 2003 278: 42131-42135. First Published on July 29, 2003; doi:10.1074/jbc.M306462200 [Abstract] [Full Text] [PDF]  

Norbert Bannert, Karin Vollhardt, Bakhtier Asomuddinov, Marion Haag, Herbert König, Stephen Norley, and Reinhard Kurth

PDZ Domain-mediated Interaction of Interleukin-16 Precursor Proteins with Myosin Phosphatase Targeting Subunits
J. Biol. Chem. 2003 278: 42190-42199. First Published on August 14, 2003; doi:10.1074/jbc.M306669200 [Abstract] [Full Text] [PDF]  

Jaewon Ko, Moonseok Na, Seho Kim, Jae-Ran Lee, and Eunjoon Kim

Interaction of the ERC Family of RIM-binding Proteins with the Liprin- Family of Multidomain Proteins
J. Biol. Chem. 2003 278: 42377-42385. First Published on August 15, 2003; doi:10.1074/jbc.M307561200 [Abstract] [Full Text] [PDF]  

Laurence Brewer, Michele Corzett, Edmond Y. Lau, and Rod Balhorn

Dynamics of Protamine 1 Binding to Single DNA Molecules
J. Biol. Chem. 2003 278: 42403-42408. First Published on August 11, 2003; doi:10.1074/jbc.M303610200 [Abstract] [Full Text] [PDF]  

Diane M. Casey, Toshiki Yagi, Ritsu Kamiya, and George B. Witman

DC3, the Smallest Subunit of the Chlamydomonas Flagellar Outer Dynein Arm-docking Complex, Is a Redox-sensitive Calcium-binding Protein
J. Biol. Chem. 2003 278: 42652-42659. First Published on August 14, 2003; doi:10.1074/jbc.M303064200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Antoni Barrientos, Danielle Pierre, Johnson Lee, and Alexander Tzagoloff

Cytochrome oxidase assembly does not require catalytically active cytochrome c.
J. Biol. Chem. 2003 278: 42728. [Full Text] [PDF]  

HaJeung Park, Si Wu, A. Keith Dunker, and ChulHee Kang

Polymerization of calsequestrin. Implications for Ca²⁺ regulation.
J. Biol. Chem. 2003 278: 42728. [Full Text] [PDF]  

Bernd Nilius, Jean Prenen, Guy Droogmans, Thomas Voets, Rudi Vennekens, Marc Freichel, Ulrich Wissenbach, and Veit Flockerzi

Voltage dependence of the Ca²⁺-activated cation channel TRPM4.
J. Biol. Chem. 2003 278: 42728. [Full Text] [PDF]  

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