Minireviews:

Patrick Sung, Lumir Krejci, Stephen Van Komen, and Michael G. Sehorn

Rad51 Recombinase and Recombination Mediators
J. Biol. Chem. 2003 278: 42729-42732. First Published on August 11, 2003; doi:10.1074/jbc.R300027200 [Full Text] [PDF]  

Accelerated Publications:

Yong Cai, Jingji Jin, Chieri Tomomori-Sato, Shigeo Sato, Irina Sorokina, Tari J. Parmely, Ronald C. Conaway, and Joan Weliky Conaway

Identification of New Subunits of the Multiprotein Mammalian TRRAP/TIP60-containing Histone Acetyltransferase Complex
J. Biol. Chem. 2003 278: 42733-42736. First Published on September 8, 2003; doi:10.1074/jbc.C300389200 [Abstract] [Full Text] [PDF] Supplemental Data  

DNA: Replication, Repair, and Recombination:

Dragana Stefanovic, Slavica Stanojcic, Alessandro Vindigni, Alexander Ochem, and Arturo Falaschi

In Vitro Protein-DNA Interactions at the Human Lamin B2 Replication Origin
J. Biol. Chem. 2003 278: 42737-42743. First Published on August 5, 2003; doi:10.1074/jbc.M307058200 [Abstract] [Full Text] [PDF]  

Janaki Veeraraghavan, Marie L. Rossi, and Robert A. Bambara

Analysis of DNA Replication Intermediates Suggests Mechanisms of Repeat Sequence Expansion
J. Biol. Chem. 2003 278: 42854-42866. First Published on August 5, 2003; doi:10.1074/jbc.M305137200 [Abstract] [Full Text] [PDF]  

Alexander Y. Lushnikov, Alexey Bogdanov, and Yuri L. Lyubchenko

DNA Recombination: HOLLIDAY JUNCTIONS DYNAMICS AND BRANCH MIGRATION
J. Biol. Chem. 2003 278: 43130-43134. First Published on August 29, 2003; doi:10.1074/jbc.M308228200 [Abstract] [Full Text] [PDF] Supplemental Data  

Polina V. Shcherbakova, Youri I. Pavlov, Olga Chilkova, Igor B. Rogozin, Erik Johansson, and Thomas A. Kunkel

Unique Error Signature of the Four-subunit Yeast DNA Polymerase
J. Biol. Chem. 2003 278: 43770-43780. First Published on July 25, 2003; doi:10.1074/jbc.M306893200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Mario P. Tschan, Kimberlee M. Fischer, Vivian S. Fung, Farzaneh Pirnia, Markus M. Borner, Martin F. Fey, Andreas Tobler, and Bruce E. Torbett

Alternative Splicing of the Human Cyclin D-binding Myb-like Protein (hDMP1) Yields a Truncated Protein Isoform That Alters Macrophage Differentiation Patterns
J. Biol. Chem. 2003 278: 42750-42760. First Published on August 12, 2003; doi:10.1074/jbc.M307067200 [Abstract] [Full Text] [PDF]  

Xiaomin Mu and Chawnshang Chang

TR3 Orphan Nuclear Receptor Mediates Apoptosis through Up-regulating E2F1 in Human Prostate Cancer LNCaP Cells
J. Biol. Chem. 2003 278: 42840-42845. First Published on August 28, 2003; doi:10.1074/jbc.M305594200 [Abstract] [Full Text] [PDF]  

Daniel M. Fass, Jennifer E. F. Butler, and Richard H. Goodman

Deacetylase Activity Is Required for cAMP Activation of a Subset of CREB Target Genes
J. Biol. Chem. 2003 278: 43014-43019. First Published on August 25, 2003; doi:10.1074/jbc.M305905200 [Abstract] [Full Text] [PDF]  

Emanuel Rosonina, Malina A. Bakowski, Susan McCracken, and Benjamin J. Blencowe

Transcriptional Activators Control Splicing and 3'-End Cleavage Levels
J. Biol. Chem. 2003 278: 43034-43040. First Published on August 25, 2003; doi:10.1074/jbc.M307289200 [Abstract] [Full Text] [PDF]  

Thanaset Senawong, Valerie J. Peterson, Dorina Avram, David M. Shepherd, Roy A. Frye, Saverio Minucci, and Mark Leid

Involvement of the Histone Deacetylase SIRT1 in Chicken Ovalbumin Upstream Promoter Transcription Factor (COUP-TF)-interacting Protein 2-mediated Transcriptional Repression
J. Biol. Chem. 2003 278: 43041-43050. First Published on August 19, 2003; doi:10.1074/jbc.M307477200 [Abstract] [Full Text] [PDF]  

Natalia Zakharova, Elena S. Lymar, Edward Yang, Sohail Malik, J. Jillian Zhang, Robert G. Roeder, and James E. Darnell, Jr.

Distinct Transcriptional Activation Functions of STAT1 and STAT1 on DNA and Chromatin Templates
J. Biol. Chem. 2003 278: 43067-43073. First Published on August 25, 2003; doi:10.1074/jbc.M308166200 [Abstract] [Full Text] [PDF]  

Xiaoli Shi, Kate Chabarek, Alice Budai, and Zhiwu Zhu

Iron Requirement for GAL Gene Induction in the Yeast Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 43110-43113. First Published on August 27, 2003; doi:10.1074/jbc.M307011200 [Abstract] [Full Text] [PDF]  

Clara I. Rodríguez, Núria Gironès, and Manuel Fresno

Cha, a Basic Helix-Loop-Helix Transcription Factor Involved in the Regulation of Upstream Stimulatory Factor Activity
J. Biol. Chem. 2003 278: 43135-43145. First Published on August 15, 2003; doi:10.1074/jbc.M300053200 [Abstract] [Full Text] [PDF]  

Priya Prasannan, Schuyler Pike, Kun Peng, Barry Shane, and Dean R. Appling

Human Mitochondrial C₁-Tetrahydrofolate Synthase: GENE STRUCTURE, TISSUE DISTRIBUTION OF THE MRNA, AND IMMUNOLOCALIZATION IN CHINESE HAMSTER OVARY CELLS
J. Biol. Chem. 2003 278: 43178-43187. First Published on August 22, 2003; doi:10.1074/jbc.M304319200 [Abstract] [Full Text] [PDF]  

Bailing Li, John R. Dedman, and Marcia A. Kaetzel

Intron Disruption of the Annexin IV Gene Reveals Novel Transcripts
J. Biol. Chem. 2003 278: 43276-43283. First Published on August 11, 2003; doi:10.1074/jbc.M306361200 [Abstract] [Full Text] [PDF]  

Christian Frank, Manuel Macias Gonzalez, Carita Oinonen, Thomas W. Dunlop, and Carsten Carlberg

Characterization of DNA Complexes Formed by the Nuclear Receptor Constitutive Androstane Receptor
J. Biol. Chem. 2003 278: 43299-43310. First Published on August 1, 2003; doi:10.1074/jbc.M305186200 [Abstract] [Full Text] [PDF]  

Evelyn M. Springhetti, Natalia E. Istomina, James C. Whisstock, Tatiana Nikitina, Chris L. Woodcock, and Sergei A. Grigoryev

Role of the M-loop and Reactive Center Loop Domains in the Folding and Bridging of Nucleosome Arrays by MENT
J. Biol. Chem. 2003 278: 43384-43393. First Published on August 19, 2003; doi:10.1074/jbc.M307635200 [Abstract] [Full Text] [PDF]  

Kiyoshi Higashi, Yutaka Inagaki, Ko Fujimori, Atsuhito Nakao, Hideo Kaneko, and Iwao Nakatsuka

Interferon- Interferes with Transforming Growth Factor- Signaling through Direct Interaction of YB-1 with Smad3
J. Biol. Chem. 2003 278: 43470-43479. First Published on August 13, 2003; doi:10.1074/jbc.M302339200 [Abstract] [Full Text] [PDF]  

Jihane Basbous, Charlotte Arpin, Gilles Gaudray, Marc Piechaczyk, Christian Devaux, and Jean-Michel Mesnard

The HBZ Factor of Human T-cell Leukemia Virus Type I Dimerizes with Transcription Factors JunB and c-Jun and Modulates Their Transcriptional Activity
J. Biol. Chem. 2003 278: 43620-43627. First Published on August 22, 2003; doi:10.1074/jbc.M307275200 [Abstract] [Full Text] [PDF]  

Matthew S. Goldberg, Sheila M. Fleming, James J. Palacino, Carlos Cepeda, Hoa A. Lam, Anushree Bhatnagar, Edward G. Meloni, Nanping Wu, Larry C. Ackerson, Gloria J. Klapstein, Mahadevan Gajendiran, Bryan L. Roth, Marie-Françoise Chesselet, Nigel T. Maidment, Michael S. Levine, and Jie Shen

Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons
J. Biol. Chem. 2003 278: 43628-43635. First Published on August 20, 2003; doi:10.1074/jbc.M308947200 [Abstract] [Full Text] [PDF]  

Mark Gagliardi, Scott Maynard, Tetsuaki Miyake, Natalie Rodrigues, Sie Lung Tjew, Eric Cabannes, and Pierre-André Bédard

Opposing Roles of C/EBP and AP-1 in the Control of Fibroblast Proliferation and Growth Arrest-specific Gene Expression
J. Biol. Chem. 2003 278: 43846-43854. First Published on August 1, 2003; doi:10.1074/jbc.M304085200 [Abstract] [Full Text] [PDF]  

RNA: Structure, Metabolism, and Catalysis:

Tina Persson, Simona Cuzic, and Roland K. Hartmann

Catalysis by RNase P RNA: UNIQUE FEATURES AND UNPRECEDENTED ACTIVE SITE PLASTICITY
J. Biol. Chem. 2003 278: 43394-43401. First Published on August 6, 2003; doi:10.1074/jbc.M305939200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Dagmar Hahn, Anastassios Pischitzis, Sandra Roesmann, Marianne K. Hansen, Boris Leuenberger, Ursula Luginbuehl, and Erwin E. Sterchi

Phorbol 12-Myristate 13-Acetate-induced Ectodomain Shedding and Phosphorylation of the Human Meprin Metalloprotease
J. Biol. Chem. 2003 278: 42829-42839. First Published on August 26, 2003; doi:10.1074/jbc.M211169200 [Abstract] [Full Text] [PDF]  

Malgorzata Goralska, Benjamin L. Holley, and M. Christine McGahan

Identification of a Mechanism by Which Lens Epithelial Cells Limit Accumulation of Overexpressed Ferritin H-chain
J. Biol. Chem. 2003 278: 42920-42926. First Published on August 14, 2003; doi:10.1074/jbc.M305827200 [Abstract] [Full Text] [PDF]  

F. Scott Heinemann, George Korza, and Juris Ozols

A Plasminogen-like Protein Selectively Degrades Stearoyl-CoA Desaturase in Liver Microsomes
J. Biol. Chem. 2003 278: 42966-42975. First Published on August 19, 2003; doi:10.1074/jbc.M306240200 [Abstract] [Full Text] [PDF]  

Alessandra Magnifico, Seth Ettenberg, Cuihong Yang, Jennifer Mariano, Swati Tiwari, Shengyun Fang, Stan Lipkowitz, and Allan M. Weissman

WW Domain HECT E3s Target Cbl RING Finger E3s for Proteasomal Degradation
J. Biol. Chem. 2003 278: 43169-43177. First Published on August 7, 2003; doi:10.1074/jbc.M308009200 [Abstract] [Full Text] [PDF]  

Stacey M. Arnold and Randal J. Kaufman

The Noncatalytic Portion of Human UDP-glucose:Glycoprotein Glucosyltransferase I Confers UDP-glucose Binding and Transferase Function to the Catalytic Domain
J. Biol. Chem. 2003 278: 43320-43328. First Published on August 11, 2003; doi:10.1074/jbc.M305800200 [Abstract] [Full Text] [PDF]  

Yukiko Yoshida, Fuminori Tokunaga, Tomoki Chiba, Kazuhiro Iwai, Keiji Tanaka, and Tadashi Tai

Fbs2 Is a New Member of the E3 Ubiquitin Ligase Family That Recognizes Sugar Chains
J. Biol. Chem. 2003 278: 43877-43884. First Published on August 25, 2003; doi:10.1074/jbc.M304157200 [Abstract] [Full Text] [PDF]  

Genomics, Proteomics, and Bioinformatics:

Bertrand Boisson, Carmela Giglione, and Thierry Meinnel

Unexpected Protein Families Including Cell Defense Components Feature in the N-Myristoylome of a Higher Eukaryote
J. Biol. Chem. 2003 278: 43418-43429. First Published on August 11, 2003; doi:10.1074/jbc.M307321200 [Abstract] [Full Text] [PDF] Supplemental Data  

Protein Structure and Folding:

Christian Hundahl, Angela Fago, Hans Malte, and Roy E. Weber

Allosteric Effect of Water in Fish and Human Hemoglobins
J. Biol. Chem. 2003 278: 42769-42773. First Published on August 17, 2003; doi:10.1074/jbc.M307515200 [Abstract] [Full Text] [PDF]  

Kevin J. Barnham, Giuseppe D. Ciccotosto, Anna K. Tickler, Feda E. Ali, Danielle G. Smith, Nicholas A. Williamson, Yuen-Han Lam, Darryl Carrington, Deborah Tew, Gulcan Kocak, Irene Volitakis, Frances Separovic, Colin J. Barrow, John D. Wade, Colin L. Masters, Robert A. Cherny, Cyril C. Curtain, Ashley I. Bush, and Roberto Cappai

Neurotoxic, Redox-competent Alzheimer's -Amyloid Is Released from Lipid Membrane by Methionine Oxidation
J. Biol. Chem. 2003 278: 42959-42965. First Published on August 18, 2003; doi:10.1074/jbc.M305494200 [Abstract] [Full Text] [PDF]  

Agnieszka Polit, Piotr Bonarek, Barbara Kepys, Sylwia Kedracka-Krok, Andrzej Górecki, and Zygmunt Wasylewski

Kinetic Studies of cAMP-induced Allosteric Changes in Mutants T127I, S128A, and T127I/S128A of the cAMP Receptor Protein from Escherichia coli
J. Biol. Chem. 2003 278: 43020-43026. First Published on August 25, 2003; doi:10.1074/jbc.M306398200 [Abstract] [Full Text] [PDF]  

Karsten Bruns, Torgils Fossen, Victor Wray, Peter Henklein, Uwe Tessmer, and Ulrich Schubert

Structural Characterization of the HIV-1 Vpr N Terminus: EVIDENCE OF cis/trans-PROLINE ISOMERISM
J. Biol. Chem. 2003 278: 43188-43201. First Published on July 23, 2003; doi:10.1074/jbc.M305413200 [Abstract] [Full Text] [PDF] Supplemental Data  

Kerstin Zander, Michael P. Sherman, Uwe Tessmer, Karsten Bruns, Victor Wray, Alexander T. Prechtel, Evelyn Schubert, Peter Henklein, Jeremy Luban, Jason Neidleman, Warner C. Greene, and Ulrich Schubert

Cyclophilin A Interacts with HIV-1 Vpr and Is Required for Its Functional Expression
J. Biol. Chem. 2003 278: 43202-43213. First Published on July 23, 2003; doi:10.1074/jbc.M305414200 [Abstract] [Full Text] [PDF]  

James F. Head, Tanya R. Mealy, Francis X. McCormack, and Barbara A. Seaton

Crystal Structure of Trimeric Carbohydrate Recognition and Neck Domains of Surfactant Protein A
J. Biol. Chem. 2003 278: 43254-43260. First Published on August 11, 2003; doi:10.1074/jbc.M305628200 [Abstract] [Full Text] [PDF]  

Vanessa A. Morais, Adam S. Crystal, Donald S. Pijak, Dan Carlin, Júlia Costa, Virginia M.-Y. Lee, and Robert W. Doms

The Transmembrane Domain Region of Nicastrin Mediates Direct Interactions with APH-1 and the -Secretase Complex
J. Biol. Chem. 2003 278: 43284-43291. First Published on August 12, 2003; doi:10.1074/jbc.M305685200 [Abstract] [Full Text] [PDF]  

Zhen Zhao, Yi Peng, Shu-feng Hao, Zong-hao Zeng, and Chih-chen Wang

Dimerization by Domain Hybridization Bestows Chaperone and Isomerase Activities
J. Biol. Chem. 2003 278: 43292-43298. First Published on August 21, 2003; doi:10.1074/jbc.M306945200 [Abstract] [Full Text] [PDF]  

Rieko Ishima, Dennis A. Torchia, Shannon M. Lynch, Angela M. Gronenborn, and John M. Louis

Solution Structure of the Mature HIV-1 Protease Monomer: INSIGHT INTO THE TERTIARY FOLD AND STABILITY OF A PRECURSOR
J. Biol. Chem. 2003 278: 43311-43319. First Published on August 21, 2003; doi:10.1074/jbc.M307549200 [Abstract] [Full Text] [PDF]  

Dongyuan Wang, Nina V. Visser, Marten Veenhuis, and Ida J. van der Klei

Physical Interactions of the Peroxisomal Targeting Signal 1 Receptor Pex5p, Studied by Fluorescence Correlation Spectroscopy
J. Biol. Chem. 2003 278: 43340-43345. First Published on August 20, 2003; doi:10.1074/jbc.M307789200 [Abstract] [Full Text] [PDF]  

Sophie Vanwetswinkel, Jan Kriek, Gregers R. Andersen, Peter Güntert, Jan Dijk, Gerard W. Canters, and Gregg Siegal

Solution Structure of the 162 Residue C-terminal Domain of Human Elongation Factor 1B
J. Biol. Chem. 2003 278: 43443-43451. First Published on August 13, 2003; doi:10.1074/jbc.M306031200 [Abstract] [Full Text] [PDF]  

Dan Lu, Juqun Shen, Marie D. Vil, Haifan Zhang, Xenia Jimenez, Peter Bohlen, Larry Witte, and Zhenping Zhu

Tailoring in Vitro Selection for a Picomolar Affinity Human Antibody Directed against Vascular Endothelial Growth Factor Receptor 2 for Enhanced Neutralizing Activity
J. Biol. Chem. 2003 278: 43496-43507. First Published on August 12, 2003; doi:10.1074/jbc.M307742200 [Abstract] [Full Text] [PDF]  

Yukiko Noda, Motoyuki Kohjima, Tomoko Izaki, Kazuhisa Ota, Sosuke Yoshinaga, Fuyuhiko Inagaki, Takashi Ito, and Hideki Sumimoto

Molecular Recognition in Dimerization between PB1 Domains
J. Biol. Chem. 2003 278: 43516-43524. First Published on August 14, 2003; doi:10.1074/jbc.M306330200 [Abstract] [Full Text] [PDF]  

Mitsuhiro Takeda, Hiroaki Terasawa, Masayoshi Sakakura, Yoshiki Yamaguchi, Masahiro Kajiwara, Hiroto Kawashima, Masayuki Miyasaka, and Ichio Shimada

Hyaluronan Recognition Mode of CD44 Revealed by Cross-saturation and Chemical Shift Perturbation Experiments
J. Biol. Chem. 2003 278: 43550-43555. First Published on August 19, 2003; doi:10.1074/jbc.M308199200 [Abstract] [Full Text] [PDF]  

J. Sivaraman, Yunge Li, Jerel Banks, David E. Cane, Allan Matte, and Miroslaw Cygler

Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway
J. Biol. Chem. 2003 278: 43682-43690. First Published on August 1, 2003; doi:10.1074/jbc.M306344200 [Abstract] [Full Text] [PDF]  

Elliott J. Stollar, Ugo Mayor, Simon C. Lovell, Luca Federici, Stefan M. V. Freund, Alan R. Fersht, and Ben F. Luisi

Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS
J. Biol. Chem. 2003 278: 43699-43708. First Published on August 15, 2003; doi:10.1074/jbc.M308029200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ulrich Baxa, Kimberly L. Taylor, Joseph S. Wall, Martha N. Simon, Naiqian Cheng, Reed B. Wickner, and Alasdair C. Steven

Architecture of Ure2p Prion Filaments: THE N-TERMINAL DOMAINS FORM A CENTRAL CORE FIBER
J. Biol. Chem. 2003 278: 43717-43727. First Published on August 12, 2003; doi:10.1074/jbc.M306004200 [Abstract] [Full Text] [PDF] Supplemental Data  

Gabriel David, Karine Blondeau, Marc Schiltz, Simon Penel, and Anita Lewit-Bentley

YodA from Escherichia coli Is a Metal-binding, Lipocalin-like Protein
J. Biol. Chem. 2003 278: 43728-43735. First Published on August 8, 2003; doi:10.1074/jbc.M304484200 [Abstract] [Full Text] [PDF]  

Mark D. Carr, Marieke J. Bloemink, Ellen Dentten, Adam O. Whelan, Stephen V. Gordon, Geoff Kelly, Thomas A. Frenkiel, R. Glyn Hewinson, and Richard A. Williamson

Solution Structure of the Mycobacterium tuberculosis Complex Protein MPB70: FROM TUBERCULOSIS PATHOGENESIS TO INHERITED HUMAN CORNEAL DISEASE
J. Biol. Chem. 2003 278: 43736-43743. First Published on August 12, 2003; doi:10.1074/jbc.M307235200 [Abstract] [Full Text] [PDF]  

Aalim M. Weljie, Kindal M. Robertson, and Hans J. Vogel

Conformational Changes in the Ca²⁺-regulatory Region from Soybean Calcium-dependent Protein Kinase-: FLUORESCENCE RESONANCE ENERGY TRANSFER STUDIES
J. Biol. Chem. 2003 278: 43764-43769. First Published on August 26, 2003; doi:10.1074/jbc.M306799200 [Abstract] [Full Text] [PDF]  

Szilvia Benko, James D. Love, Marta Beládi, John W. R. Schwabe, and Laszlo Nagy

Molecular Determinants of the Balance between Co-repressor and Co-activator Recruitment to the Retinoic Acid Receptor
J. Biol. Chem. 2003 278: 43797-43806. First Published on August 12, 2003; doi:10.1074/jbc.M306199200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Eva Bürkert, Christina Arnold, Tove Hammarberg, Olof Rådmark, Dieter Steinhilber, and Oliver Werz

The C2-like -Barrel Domain Mediates the Ca²⁺-dependent Resistance of 5-Lipoxygenase Activity Against Inhibition by Glutathione Peroxidase-1
J. Biol. Chem. 2003 278: 42846-42853. First Published on July 31, 2003; doi:10.1074/jbc.M302471200 [Abstract] [Full Text] [PDF]  

Paola Fiorani, Alessandro Bruselles, Mattia Falconi, Giovanni Chillemi, Alessandro Desideri, and Piero Benedetti

Single Mutation in the Linker Domain Confers Protein Flexibility and Camptothecin Resistance to Human Topoisomerase I
J. Biol. Chem. 2003 278: 43268-43275. First Published on August 6, 2003; doi:10.1074/jbc.M303899200 [Abstract] [Full Text] [PDF]  

Yi Pei and Stewart Shuman

Characterization of the Schizosaccharomyces pombe Cdk9/Pch1 Protein Kinase: Spt5 PHOSPHORYLATION, AUTOPHOSPHORYLATION, AND MUTATIONAL ANALYSIS
J. Biol. Chem. 2003 278: 43346-43356. First Published on August 5, 2003; doi:10.1074/jbc.M307319200 [Abstract] [Full Text] [PDF]  

Andrea Schmidt, Christian Jelsch, Peter Østergaard, Wojciech Rypniewski, and Victor S. Lamzin

Trypsin Revisited: CRYSTALLOGRAPHY AT (SUB) ATOMIC RESOLUTION AND QUANTUM CHEMISTRY REVEALING DETAILS OF CATALYSIS
J. Biol. Chem. 2003 278: 43357-43362. First Published on August 22, 2003; doi:10.1074/jbc.M306944200 [Abstract] [Full Text] [PDF]  

R. Max Wynn, Mischa Machius, Jacinta L. Chuang, Jun Li, Diana R. Tomchick, and David T. Chuang

Roles of His²⁹¹- and His¹⁴⁶-' in the Reductive Acylation Reaction Catalyzed by Human Branched-chain -Ketoacid Dehydrogenase: REFINED PHOSPHORYLATION LOOP STRUCTURE IN THE ACTIVE SITE
J. Biol. Chem. 2003 278: 43402-43410. First Published on August 5, 2003; doi:10.1074/jbc.M306204200 [Abstract] [Full Text] [PDF]  

Anna M. Blom, Bruno O. Villoutreix, and Björn Dahlbäck

Mutations in -Chain of C4BP That Selectively Affect Its Factor I Cofactor Function
J. Biol. Chem. 2003 278: 43437-43442. First Published on July 31, 2003; doi:10.1074/jbc.M306620200 [Abstract] [Full Text] [PDF]  

James B. Thoden, Zhihao Zhuang, Debra Dunaway-Mariano, and Hazel M. Holden

The Structure of 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. strain SU
J. Biol. Chem. 2003 278: 43709-43716. First Published on August 7, 2003; doi:10.1074/jbc.M308198200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Sherwin Y. Chan and Dean R. Appling

Regulation of S-Adenosylmethionine Levels in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 43051-43059. First Published on August 22, 2003; doi:10.1074/jbc.M308696200 [Abstract] [Full Text] [PDF]  

Hana Antonicka, Isla Ogilvie, Tanja Taivassalo, Roberto P. Anitori, Ronald G. Haller, John Vissing, Nancy G. Kennaway, and Eric A. Shoubridge

Identification and Characterization of a Common Set of Complex I Assembly Intermediates in Mitochondria from Patients with Complex I Deficiency
J. Biol. Chem. 2003 278: 43081-43088. First Published on August 26, 2003; doi:10.1074/jbc.M304998200 [Abstract] [Full Text] [PDF]  

Peter J. Holt, David J. Morgan, and Leonid A. Sazanov

The Location of NuoL and NuoM Subunits in the Membrane Domain of the Escherichia coli Complex I: IMPLICATIONS FOR THE MECHANISM OF PROTON PUMPING
J. Biol. Chem. 2003 278: 43114-43120. First Published on August 15, 2003; doi:10.1074/jbc.M308247200 [Abstract] [Full Text] [PDF]  

Edda von Roepenack-Lahaye, Mari-Anne Newman, Sebastian Schornack, Kim E. Hammond-Kosack, Thomas Lahaye, Jonathan D. G. Jones, Michael J. Daniels, and J. Maxwell Dow

p-Coumaroylnoradrenaline, a Novel Plant Metabolite Implicated in Tomato Defense against Pathogens
J. Biol. Chem. 2003 278: 43373-43383. First Published on August 4, 2003; doi:10.1074/jbc.M305084200 [Abstract] [Full Text] [PDF]  

Chun-Li Su, Carole Sztalryd, Juan Antonio Contreras, Cecilia Holm, Alan R. Kimmel, and Constantine Londos

Mutational Analysis of the Hormone-sensitive Lipase Translocation Reaction in Adipocytes
J. Biol. Chem. 2003 278: 43615-43619. First Published on June 26, 2003; doi:10.1074/jbc.M301809200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Janet A. Weigel and Paul H. Weigel

Characterization of the Recombinant Rat 175-kDa Hyaluronan Receptor for Endocytosis (HARE)
J. Biol. Chem. 2003 278: 42802-42811. First Published on August 20, 2003; doi:10.1074/jbc.M307201200 [Abstract] [Full Text] [PDF]  

Kei-ichiro Inamori, Takeshi Endo, Yoshihito Ide, Shigeru Fujii, Jianguo Gu, Koichi Honke, and Naoyuki Taniguchi

Molecular Cloning and Characterization of Human GnT-IX, a Novel 1,6-N-Acetylglucosaminyltransferase That Is Specifically Expressed in the Brain
J. Biol. Chem. 2003 278: 43102-43109. First Published on August 26, 2003; doi:10.1074/jbc.M308255200 [Abstract] [Full Text] [PDF]  

Manuel Koch, Friedrich Laub, Peihong Zhou, Rita A. Hahn, Shizuko Tanaka, Robert E. Burgeson, Donald R. Gerecke, Francesco Ramirez, and Marion K. Gordon

Collagen XXIV, a Vertebrate Fibrillar Collagen with Structural Features of Invertebrate Collagens: SELECTIVE EXPRESSION IN DEVELOPING CORNEA AND BONE
J. Biol. Chem. 2003 278: 43236-43244. First Published on July 21, 2003; doi:10.1074/jbc.M302112200 [Abstract] [Full Text] [PDF]  

Megumi Hikino, Tadahisa Mikami, Andreas Faissner, Ana-Cristina E. S. Vilela-Silva, Mauro S. G. Pavão, and Kazuyuki Sugahara

Oversulfated Dermatan Sulfate Exhibits Neurite Outgrowth-promoting Activity toward Embryonic Mouse Hippocampal Neurons: IMPLICATIONS OF DERMATAN SULFATE IN NEURITOGENESIS IN THE BRAIN
J. Biol. Chem. 2003 278: 43744-43754. First Published on August 12, 2003; doi:10.1074/jbc.M308169200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Laurent Vergnes, Jack Phan, Merav Strauss, Sherrie Tafuri, and Karen Reue

Cholesterol and Cholate Components of an Atherogenic Diet Induce Distinct Stages of Hepatic Inflammatory Gene Expression
J. Biol. Chem. 2003 278: 42774-42784. First Published on August 15, 2003; doi:10.1074/jbc.M306022200 [Abstract] [Full Text] [PDF] Supplemental Data  

Kevin W. Huggins, Lisa M. Camarota, Philip N. Howles, and David Y. Hui

Pancreatic Triglyceride Lipase Deficiency Minimally Affects Dietary Fat Absorption but Dramatically Decreases Dietary Cholesterol Absorption in Mice
J. Biol. Chem. 2003 278: 42899-42905. First Published on August 12, 2003; doi:10.1074/jbc.M303422200 [Abstract] [Full Text] [PDF]  

Nan Wang, Debin Lan, Marie Gerbod-Giannone, Patrick Linsel-Nitschke, Andreas Werner Jehle, Wengen Chen, Laurent O. Martinez, and Alan R. Tall

ATP-binding Cassette Transporter A7 (ABCA7) Binds Apolipoprotein A-I and Mediates Cellular Phospholipid but Not Cholesterol Efflux
J. Biol. Chem. 2003 278: 42906-42912. First Published on August 12, 2003; doi:10.1074/jbc.M307831200 [Abstract] [Full Text] [PDF]  

Ken Ohashi, Jun-ichi Osuga, Ryuichi Tozawa, Tetsuya Kitamine, Hiroaki Yagyu, Motohiro Sekiya, Sachiko Tomita, Hiroaki Okazaki, Yoshiaki Tamura, Naoya Yahagi, Yoko Iizuka, Kenji Harada, Takanari Gotoda, Hitoshi Shimano, Nobuhiro Yamada, and Shun Ishibashi

Early Embryonic Lethality Caused by Targeted Disruption of the 3-Hydroxy-3-methylglutaryl-CoA Reductase Gene
J. Biol. Chem. 2003 278: 42936-42941. First Published on August 14, 2003; doi:10.1074/jbc.M307228200 [Abstract] [Full Text] [PDF]  

Lijuan Liu, Anna E. Bortnick, Margaret Nickel, Padmaja Dhanasekaran, Papasani V. Subbaiah, Sissel Lund-Katz, George H. Rothblat, and Michael C. Phillips

Effects of Apolipoprotein A-I on ATP-binding Cassette Transporter A1-mediated Efflux of Macrophage Phospholipid and Cholesterol: FORMATION OF NASCENT HIGH DENSITY LIPOPROTEIN PARTICLES
J. Biol. Chem. 2003 278: 42976-42984. First Published on August 19, 2003; doi:10.1074/jbc.M308420200 [Abstract] [Full Text] [PDF]  

Angela M. Hall, Anne J. Smith, and David A. Bernlohr

Characterization of the Acyl-CoA Synthetase Activity of Purified Murine Fatty Acid Transport Protein 1
J. Biol. Chem. 2003 278: 43008-43013. First Published on August 22, 2003; doi:10.1074/jbc.M306575200 [Abstract] [Full Text] [PDF]  

Frédéric M. Vaz, Riekelt H. Houtkooper, Fredoen Valianpour, Peter G. Barth, and Ronald J. A. Wanders

Only One Splice Variant of the Human TAZ Gene Encodes a Functional Protein with a Role in Cardiolipin Metabolism
J. Biol. Chem. 2003 278: 43089-43094. First Published on August 20, 2003; doi:10.1074/jbc.M305956200 [Abstract] [Full Text] [PDF]  

Thomas Lundåsen, Wei Liao, Bo Angelin, and Mats Rudling

Leptin Induces the Hepatic High Density Lipoprotein Receptor Scavenger Receptor B Type I (SR-BI) but Not Cholesterol 7-Hydroxylase (Cyp7a1) in Leptin-deficient (ob/ob) Mice
J. Biol. Chem. 2003 278: 43224-43228. First Published on August 13, 2003; doi:10.1074/jbc.M302645200 [Abstract] [Full Text] [PDF]  

Christian Riebeling, Jeremy C. Allegood, Elaine Wang, Alfred H. Merrill, Jr., and Anthony H. Futerman

Two Mammalian Longevity Assurance Gene (LAG1) Family Members, trh1 and trh4, Regulate Dihydroceramide Synthesis Using Different Fatty Acyl-CoA Donors
J. Biol. Chem. 2003 278: 43452-43459. First Published on August 11, 2003; doi:10.1074/jbc.M307104200 [Abstract] [Full Text] [PDF]  

Wen-Jun Shen, Shailja Patel, Vanita Natu, Richard Hong, Jenny Wang, Salman Azhar, and Fredric B. Kraemer

Interaction of Hormone-sensitive Lipase with Steroidogeneic Acute Regulatory Protein: FACILITATION OF CHOLESTEROL TRANSFER IN ADRENAL
J. Biol. Chem. 2003 278: 43870-43876. First Published on August 18, 2003; doi:10.1074/jbc.M303934200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Chang-sheng S. Chang, Riccardo Olcese, and Richard W. Olsen

A Single M1 Residue in the 2 Subunit Alters Channel Gating of GABA_A Receptor in Anesthetic Modulation and Direct Activation
J. Biol. Chem. 2003 278: 42821-42828. First Published on August 25, 2003; doi:10.1074/jbc.M306978200 [Abstract] [Full Text] [PDF]  

Xinpo Jiang, Evan W. Newell, and Lyanne C. Schlichter

Regulation of a TRPM7-like Current in Rat Brain Microglia
J. Biol. Chem. 2003 278: 42867-42876. First Published on August 6, 2003; doi:10.1074/jbc.M304487200 [Abstract] [Full Text] [PDF]  

Paula Aracena, Gina Sánchez, Paulina Donoso, Susan L. Hamilton, and Cecilia Hidalgo

S-Glutathionylation Decreases Mg²⁺ Inhibition and S-Nitrosylation Enhances Ca²⁺ Activation of RyR1 Channels
J. Biol. Chem. 2003 278: 42927-42935. First Published on August 14, 2003; doi:10.1074/jbc.M306969200 [Abstract] [Full Text] [PDF]  

Torsten Pirch, Silke Landmeier, and Heinrich Jung

Transmembrane Domain II of the Na⁺/Proline Transporter PutP of Escherichia coli Forms Part of a Conformationally Flexible, Cytoplasmic Exposed Aqueous Cavity within the Membrane
J. Biol. Chem. 2003 278: 42942-42949. First Published on August 15, 2003; doi:10.1074/jbc.M308253200 [Abstract] [Full Text] [PDF]  

Elia Zomot and Baruch I. kanner

The Interaction of the -Aminobutyric Acid Transporter GAT-1 with the Neurotransmitter Is Selectively Impaired by Sulfhydryl Modification of a Conformationally Sensitive Cysteine Residue Engineered into Extracellular Loop IV
J. Biol. Chem. 2003 278: 42950-42958. First Published on August 18, 2003; doi:10.1074/jbc.M209307200 [Abstract] [Full Text] [PDF]  

Carole Dabney-Smith, Hiroki Mori, and Kenneth Cline

Requirement of a Tha4-conserved Transmembrane Glutamate in Thylakoid Tat Translocase Assembly Revealed by Biochemical Complementation
J. Biol. Chem. 2003 278: 43027-43033. First Published on August 25, 2003; doi:10.1074/jbc.M307923200 [Abstract] [Full Text] [PDF]  

Raul A. Marinelli, Pamela S. Tietz, Ariel J. Caride, Bing Q. Huang, and Nicholas F. LaRusso

Water Transporting Properties of Hepatocyte Basolateral and Canalicular Plasma Membrane Domains
J. Biol. Chem. 2003 278: 43157-43162. First Published on August 25, 2003; doi:10.1074/jbc.M305899200 [Abstract] [Full Text] [PDF]  

Daisuke Sugiyama, Hiroyuki Kusuhara, Hirokazu Taniguchi, Shumpei Ishikawa, Yoshitane Nozaki, Hiroyuki Aburatani, and Yuichi Sugiyama

Functional Characterization of Rat Brain-specific Organic Anion Transporter (Oatp14) at the Blood-Brain Barrier: HIGH AFFINITY TRANSPORTER FOR THYROXINE
J. Biol. Chem. 2003 278: 43489-43495. First Published on August 15, 2003; doi:10.1074/jbc.M306933200 [Abstract] [Full Text] [PDF]  

Maria Casamassima, M. Cristina D'Adamo, Mauro Pessia, and Stephen J. Tucker

Identification of a Heteromeric Interaction That Influences the Rectification, Gating, and pH Sensitivity of Kir4.1/Kir5.1 Potassium Channels
J. Biol. Chem. 2003 278: 43533-43540. First Published on August 15, 2003; doi:10.1074/jbc.M306596200 [Abstract] [Full Text] [PDF]  

Xiaomeng Ren, Stuart H. Shand, and Koichi Takimoto

Effective Association of Kv Channel-interacting Proteins with Kv4 Channel Is Mediated with Their Unique Core Peptide
J. Biol. Chem. 2003 278: 43564-43570. First Published on August 19, 2003; doi:10.1074/jbc.M302337200 [Abstract] [Full Text] [PDF]  

Shigeo Wakabayashi, Takashi Hisamitsu, Tianxiang Pang, and Munekazu Shigekawa

Kinetic Dissection of Two Distinct Proton Binding Sites in Na⁺/H⁺ Exchangers by Measurement of Reverse Mode Reaction
J. Biol. Chem. 2003 278: 43580-43585. First Published on August 19, 2003; doi:10.1074/jbc.M306690200 [Abstract] [Full Text] [PDF]  

Barbara Much, Christian Wahl-Schott, Xiangang Zong, Angela Schneider, Ludwig Baumann, Sven Moosmang, Andreas Ludwig, and Martin Biel

Role of Subunit Heteromerization and N-Linked Glycosylation in the Formation of Functional Hyperpolarization-activated Cyclic Nucleotide-gated Channels
J. Biol. Chem. 2003 278: 43781-43786. First Published on August 19, 2003; doi:10.1074/jbc.M306958200 [Abstract] [Full Text] [PDF]  

Ellappan Babu, Yoshikatsu Kanai, Arthit Chairoungdua, Do Kyung Kim, Yuji Iribe, Sahatchai Tangtrongsup, Promsuk Jutabha, Yuewei Li, Nesar Ahmed, Shinichi Sakamoto, Naohiko Anzai, Seishi Nagamori, and Hitoshi Endou

Identification of a Novel System L Amino Acid Transporter Structurally Distinct from Heterodimeric Amino Acid Transporters
J. Biol. Chem. 2003 278: 43838-43845. First Published on August 20, 2003; doi:10.1074/jbc.M305221200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Mary Hunzicker-Dunn, George Barisas, Jinming Song, and Deborah A. Roess

Membrane Organization of Luteinizing Hormone Receptors Differs between Actively Signaling and Desensitized Receptors
J. Biol. Chem. 2003 278: 42744-42749. First Published on August 20, 2003; doi:10.1074/jbc.M306133200 [Abstract] [Full Text] [PDF]  

Juliana Ivanova, Guy Salama, Robert M. Clancy, Nina F. Schor, Karen D. Nylander, and Detcho A. Stoyanovsky

Formation of Nitroxyl and Hydroxyl Radical in Solutions of Sodium Trioxodinitrate: EFFECTS OF pH AND CYTOTOXICITY
J. Biol. Chem. 2003 278: 42761-42768. First Published on August 14, 2003; doi:10.1074/jbc.M305544200 [Abstract] [Full Text] [PDF]  

Jorge E. Domínguez, M.^a Carmen Muñoz, Delia Zafra, Isabel Sánchez-Pérez, Susanna Baqué, Martine Caron, Ciro Mercurio, Albert Barberà, Rosario Perona, Ramon Gomis, and Joan J. Guinovart

The Antidiabetic Agent Sodium Tungstate Activates Glycogen Synthesis through an Insulin Receptor-independent Pathway
J. Biol. Chem. 2003 278: 42785-42794. First Published on August 18, 2003; doi:10.1074/jbc.M308334200 [Abstract] [Full Text] [PDF]  

Liangping Yuan, Wen-Mei Yu, and Cheng-Kui Qu

DNA Damage-induced G₂/M Checkpoint in SV40 Large T Antigen-immortalized Embryonic Fibroblast Cells Requires SHP-2 Tyrosine Phosphatase
J. Biol. Chem. 2003 278: 42812-42820. First Published on August 22, 2003; doi:10.1074/jbc.M305075200 [Abstract] [Full Text] [PDF]  

Jay H. Chang, Eric Mellon, N. Carolyn Schanen, and Jeffery L. Twiss

Persistent TrkA Activity Is Necessary to Maintain Transcription in Neuronally Differentiated PC12 Cells
J. Biol. Chem. 2003 278: 42877-42885. First Published on August 8, 2003; doi:10.1074/jbc.M308155200 [Abstract] [Full Text] [PDF]  

Tzefu Hsieh, Rebecca E. Gordon, David R. Clemmons, Walker H. Busby, Jr., and Cunming Duan

Regulation of Vascular Smooth Muscle Cell Responses to Insulin-like Growth Factor (IGF)-I by Local IGF-binding Proteins
J. Biol. Chem. 2003 278: 42886-42892. First Published on August 12, 2003; doi:10.1074/jbc.M303835200 [Abstract] [Full Text] [PDF]  

Runxiang Zhao, Xueqi Fu, Lirong Teng, Qingshan Li, and Zhizhuang Joe Zhao

Blocking the Function of Tyrosine Phosphatase SHP-2 by Targeting Its Src Homology 2 Domains
J. Biol. Chem. 2003 278: 42893-42898. First Published on August 11, 2003; doi:10.1074/jbc.M306136200 [Abstract] [Full Text] [PDF]  

Michael J. Wick, Fresnida J. Ramos, Hui Chen, Michael J. Quon, Lily Q. Dong, and Feng Liu

Mouse 3-Phosphoinositide-dependent Protein Kinase-1 Undergoes Dimerization and trans-Phosphorylation in the Activation Loop
J. Biol. Chem. 2003 278: 42913-42919. First Published on August 14, 2003; doi:10.1074/jbc.M304172200 [Abstract] [Full Text] [PDF]  

Mei Sun, Lin Yang, Richard I. Feldman, Xia-meng Sun, Kapil N. Bhalla, Richard Jove, Santo V. Nicosia, and Jin Q. Cheng

Activation of Phosphatidylinositol 3-Kinase/Akt Pathway by Androgen through Interaction of p85, Androgen Receptor, and Src
J. Biol. Chem. 2003 278: 42992-43000. First Published on August 21, 2003; doi:10.1074/jbc.M306295200 [Abstract] [Full Text] [PDF]  

Jiyun Yoo, Mayshan Ghiassi, Ludmila Jirmanova, Arthur G. Balliet, Barbara Hoffman, Albert J. Fornace, Jr., Dan A. Liebermann, Erwin P. Böttinger, and Anita B. Roberts

Transforming Growth Factor--induced Apoptosis Is Mediated by Smad-dependent Expression of GADD45b through p38 Activation
J. Biol. Chem. 2003 278: 43001-43007. First Published on August 21, 2003; doi:10.1074/jbc.M307869200 [Abstract] [Full Text] [PDF]  

Alexander W. Krug, Claudia Grossmann, Claudia Schuster, Ruth Freudinger, Sigrid Mildenberger, Manjapra V. Govindan, and Michael Gekle

Aldosterone Stimulates Epidermal Growth Factor Receptor Expression
J. Biol. Chem. 2003 278: 43060-43066. First Published on August 25, 2003; doi:10.1074/jbc.M308134200 [Abstract] [Full Text] [PDF]  

Wu Yin, James Mu, and Morris J. Birnbaum

Role of AMP-activated Protein Kinase in Cyclic AMP-dependent Lipolysis In 3T3-L1 Adipocytes
J. Biol. Chem. 2003 278: 43074-43080. First Published on August 25, 2003; doi:10.1074/jbc.M308484200 [Abstract] [Full Text] [PDF]  

Shinya Shimizu, Satoshi Ugi, Hiroshi Maegawa, Katsuya Egawa, Yoshihiko Nishio, Takeshi Yoshizaki, Kun Shi, Yoshio Nagai, Katsutaro Morino, Ken-ichi Nemoto, Takaaki Nakamura, Michael Bryer-Ash, and Atsunori Kashiwagi

Protein-tyrosine Phosphatase 1B as New Activator for Hepatic Lipogenesis via Sterol Regulatory Element-binding Protein-1 Gene Expression
J. Biol. Chem. 2003 278: 43095-43101. First Published on August 26, 2003; doi:10.1074/jbc.M306880200 [Abstract] [Full Text] [PDF]  

Priscilla P. Cherian, Benxu Cheng, Sumin Gu, Eugene Sprague, Lynda F. Bonewald, and Jean X. Jiang

Effects of Mechanical Strain on the Function of Gap Junctions in Osteocytes Are Mediated through the Prostaglandin EP₂ Receptor
J. Biol. Chem. 2003 278: 43146-43156. First Published on August 25, 2003; doi:10.1074/jbc.M302993200 [Abstract] [Full Text] [PDF]  

Xueli Fan, Yun Liu, and Jason J. Chen

Activation of c-Myc Contributes to Bovine Papillomavirus Type 1 E7-induced Cell Proliferation
J. Biol. Chem. 2003 278: 43163-43168. First Published on August 22, 2003; doi:10.1074/jbc.M306008200 [Abstract] [Full Text] [PDF]  

Susan S. Smyth, Vicki A. Sciorra, Yury J. Sigal, Zehra Pamuklar, Zuncai Wang, Yong Xu, Glenn D. Prestwich, and Andrew J. Morris

Lipid Phosphate Phosphatases Regulate Lysophosphatidic Acid Production and Signaling in Platelets: STUDIES USING CHEMICAL INHIBITORS OF LIPID PHOSPHATE PHOSPHATASE ACTIVITY
J. Biol. Chem. 2003 278: 43214-43223. First Published on August 8, 2003; doi:10.1074/jbc.M306709200 [Abstract] [Full Text] [PDF]  

Nicolas Bizat, Jean-Michel Hermel, Sandrine Humbert, Carine Jacquard, Christophe Créminon, Carole Escartin, Frédéric Saudou, Stan Krajewski, Philippe Hantraye, and Emmanuel Brouillet

In Vivo Calpain/Caspase Cross-talk during 3-Nitropropionic Acid-induced Striatal Degeneration: IMPLICATION OF A CALPAIN-MEDIATED CLEAVAGE OF ACTIVE CASPASE-3
J. Biol. Chem. 2003 278: 43245-43253. First Published on August 12, 2003; doi:10.1074/jbc.M305057200 [Abstract] [Full Text] [PDF]  

Manabu Murakami, Hisao Yamamura, Takashi Suzuki, Myoung-Goo Kang, Susumu Ohya, Agnieszka Murakami, Ichiro Miyoshi, Hironobu Sasano, Katsuhiko Muraki, Takuzou Hano, Noriyuki Kasai, Shinnsuke Nakayama, Kevin P. Campbell, Veit Flockerzi, Yuji Imaizumi, Teruyuki Yanagisawa, and Toshihiko Iijima

Modified Cardiovascular L-type Channels in Mice Lacking the Voltage-dependent Ca²⁺ Channel 3 Subunit
J. Biol. Chem. 2003 278: 43261-43267. First Published on August 14, 2003; doi:10.1074/jbc.M211380200 [Abstract] [Full Text] [PDF]  

Krishnan M. Dhandapani, Martin Hadman, Liesl De Sevilla, Marlene F. Wade, Virendra B. Mahesh, and Darrell W. Brann

Astrocyte Protection of Neurons: ROLE OF TRANSFORMING GROWTH FACTOR- SIGNALING VIA A c-Jun-AP-1 PROTECTIVE PATHWAY
J. Biol. Chem. 2003 278: 43329-43339. First Published on July 29, 2003; doi:10.1074/jbc.M305835200 [Abstract] [Full Text] [PDF]  

Jun Kawagoe, Masahide Ohmichi, Toshifumi Takahashi, Chika Ohshima, Seiji Mabuchi, Kazuhiro Takahashi, Hideki Igarashi, Akiko Mori-Abe, Maki Saitoh, Botao Du, Tsuyoshi Ohta, Akiko Kimura, Satoru Kyo, Masaki Inoue, and Hirohisa Kurachi

Raloxifene Inhibits Estrogen-induced Up-regulation of Telomerase Activity in a Human Breast Cancer Cell Line
J. Biol. Chem. 2003 278: 43363-43372. First Published on August 13, 2003; doi:10.1074/jbc.M304363200 [Abstract] [Full Text] [PDF]  

Fangtian Huang, Xuejun Jiang, and Alexander Sorkin

Tyrosine Phosphorylation of the 2 Subunit of Clathrin Adaptor Complex AP-2 Reveals the Role of a Di-leucine Motif in the Epidermal Growth Factor Receptor Trafficking
J. Biol. Chem. 2003 278: 43411-43417. First Published on August 4, 2003; doi:10.1074/jbc.M306072200 [Abstract] [Full Text] [PDF]  

Kanamarlapudi Venkateswarlu

Interaction Protein for Cytohesin Exchange Factors 1 (IPCEF1) Binds Cytohesin 2 and Modifies Its Activity
J. Biol. Chem. 2003 278: 43460-43469. First Published on August 14, 2003; doi:10.1074/jbc.M304078200 [Abstract] [Full Text] [PDF]  

Pavel V. Perestenko and Jeremy M. Henley

Characterization of the Intracellular Transport of GluR1 and GluR2 -Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunits in Hippocampal Neurons
J. Biol. Chem. 2003 278: 43525-43532. First Published on August 8, 2003; doi:10.1074/jbc.M306206200 [Abstract] [Full Text] [PDF]  

Sanjay Gupta, Jessica C. Fanzo, Chuanmin Hu, Dianne Cox, So Young Jang, Andrea E. Lee, Steven Greenberg, and Alessandra B. Pernis

T Cell Receptor Engagement Leads to the Recruitment of IBP, a Novel Guanine Nucleotide Exchange Factor, to the Immunological Synapse
J. Biol. Chem. 2003 278: 43541-43549. First Published on August 15, 2003; doi:10.1074/jbc.M308960200 [Abstract] [Full Text] [PDF]  

Manuela Bezzi, Meriem Hasmim, Grégory Bieler, Olivier Dormond, and Curzio Rüegg

Zoledronate Sensitizes Endothelial Cells to Tumor Necrosis Factor-induced Programmed Cell Death: EVIDENCE FOR THE SUPPRESSION OF SUSTAINED ACTIVATION OF FOCAL ADHESION KINASE AND PROTEIN KINASE B/Akt
J. Biol. Chem. 2003 278: 43603-43614. First Published on August 20, 2003; doi:10.1074/jbc.M308114200 [Abstract] [Full Text] [PDF]  

Parvaneh Rafiee, Yang Shi, Kirkwood A. Pritchard, Jr., Hitoshi Ogawa, Annie L. W. Eis, Richard A. Komorowski, Colleen M. Fitzpatrick, James S. Tweddell, S. Bert Litwin, Kathleen Mussatto, Robert D. Jaquiss, and John E. Baker

Cellular Redistribution of Inducible Hsp70 Protein in the Human and Rabbit Heart in Response to the Stress of Chronic Hypoxia: ROLE OF PROTEIN KINASES
J. Biol. Chem. 2003 278: 43636-43644. First Published on August 22, 2003; doi:10.1074/jbc.M212993200 [Abstract] [Full Text] [PDF]  

Young Sun, Yasuhiro Mochizuki, and Philip W. Majerus

Inositol 1,3,4-Trisphosphate 5/6-Kinase Inhibits Tumor Necrosis Factor-induced Apoptosis
J. Biol. Chem. 2003 278: 43645-43653. First Published on August 18, 2003; doi:10.1074/jbc.M300674200 [Abstract] [Full Text] [PDF]  

Renren Wen, Yuhong Chen, Liquan Xue, James Schuman, Shoua Yang, Stephan W. Morris, and Demin Wang

Phospholipase C2 Provides Survival Signals via Bcl2 and A1 in Different Subpopulations of B Cells
J. Biol. Chem. 2003 278: 43654-43662. First Published on August 19, 2003; doi:10.1074/jbc.M307318200 [Abstract] [Full Text] [PDF]  

Ryo Suzuki, Kazuyuki Tobe, Yasuo Terauchi, Kajuro Komeda, Naoto Kubota, Kazuhiro Eto, Toshimasa Yamauchi, Kousuke Azuma, Hideaki Kaneto, Takashi Taguchi, Teiichiro Koga, Michael S. German, Hirotaka Watada, Ryuzo Kawamori, Christopher V. E. Wright, Yoshitaka Kajimoto, Satoshi Kimura, Ryozo Nagai, and Takashi Kadowaki

Pdx1 Expression in Irs2-deficient Mouse -Cells Is Regulated in a Strain-dependent Manner
J. Biol. Chem. 2003 278: 43691-43698. First Published on July 16, 2003; doi:10.1074/jbc.M307004200 [Abstract] [Full Text] [PDF]  

Stefan N. Constantinescu, Tzvia Keren, William P. Russ, Iban Ubarretxena-Belandia, Yaniv Malka, Katharina F. Kubatzky, Donald M. Engelman, Harvey F. Lodish, and Yoav I. Henis

The Erythropoietin Receptor Transmembrane Domain Mediates Complex Formation with Viral Anemic and Polycythemic gp55 Proteins
J. Biol. Chem. 2003 278: 43755-43763. First Published on August 20, 2003; doi:10.1074/jbc.M302974200 [Abstract] [Full Text] [PDF]  

W. Bruce Sneddon, Colin A. Syme, Alessandro Bisello, Clara E. Magyar, Moulay Driss Rochdi, Jean-Luc Parent, Edward J. Weinman, Abdul B. Abou-Samra, and Peter A. Friedman

Activation-independent Parathyroid Hormone Receptor Internalization Is Regulated by NHERF1 (EBP50)
J. Biol. Chem. 2003 278: 43787-43796. First Published on August 14, 2003; doi:10.1074/jbc.M306019200 [Abstract] [Full Text] [PDF]  

Victor L. Marcheselli, Song Hong, Walter J. Lukiw, Xiao Hua Tian, Karsten Gronert, Alberto Musto, Mattie Hardy, Juan M. Gimenez, Nan Chiang, Charles N. Serhan, and Nicolas G. Bazan

Novel Docosanoids Inhibit Brain Ischemia-Reperfusion-mediated Leukocyte Infiltration and Pro-inflammatory Gene Expression
J. Biol. Chem. 2003 278: 43807-43817. First Published on August 15, 2003; doi:10.1074/jbc.M305841200 [Abstract] [Full Text] [PDF]  

Robert J. McKallip, Michael Fisher, Yoonkyung Do, Andras K. Szakal, Ursula Gunthert, Prakash S. Nagarkatti, and Mitzi Nagarkatti

Targeted Deletion of CD44v7 Exon Leads to Decreased Endothelial Cell Injury but Not Tumor Cell Killing Mediated by Interleukin-2-activated Cytolytic Lymphocytes
J. Biol. Chem. 2003 278: 43818-43830. First Published on August 6, 2003; doi:10.1074/jbc.M304467200 [Abstract] [Full Text] [PDF]  

Chandrahasa R. Yellaturu and Gadiparthi N. Rao

A Requirement for Calcium-independent Phospholipase A₂ in Thrombin-induced Arachidonic Acid Release and Growth in Vascular Smooth Muscle Cells
J. Biol. Chem. 2003 278: 43831-43837. First Published on August 19, 2003; doi:10.1074/jbc.M301472200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Darren R. Brooks, Nigel M. Hooper, and R. Elwyn Isaac

The Caenorhabditis elegans Orthologue of Mammalian Puromycin-sensitive Aminopeptidase Has Roles in Embryogenesis and Reproduction
J. Biol. Chem. 2003 278: 42795-42801. First Published on August 20, 2003; doi:10.1074/jbc.M306216200 [Abstract] [Full Text] [PDF]  

Kaoru Kikuchi, Akiyoshi Kishino, Osamu Konishi, Kazuo Kumagai, Nobuo Hosotani, Ikutaro Saji, Chikao Nakayama, and Toru Kimura

In Vitro and in Vivo Characterization of a Novel Semaphorin 3A Inhibitor, SM-216289 or Xanthofulvin
J. Biol. Chem. 2003 278: 42985-42991. First Published on August 21, 2003; doi:10.1074/jbc.M302395200 [Abstract] [Full Text] [PDF]  

Thomas L. McCarthy, Wei-Zhong Chang, Yuan Liu, and Michael Centrella

Runx2 Integrates Estrogen Activity in Osteoblasts
J. Biol. Chem. 2003 278: 43121-43129. First Published on September 1, 2003; doi:10.1074/jbc.M306531200 [Abstract] [Full Text] [PDF]  

Takatora Takada, Takenobu Katagiri, Michiyo Ifuku, Naoko Morimura, Makoto Kobayashi, Kohji Hasegawa, Akira Ogamo, and Ryutaro Kamijo

Sulfated Polysaccharides Enhance the Biological Activities of Bone Morphogenetic Proteins
J. Biol. Chem. 2003 278: 43229-43235. First Published on August 11, 2003; doi:10.1074/jbc.M300937200 [Abstract] [Full Text] [PDF]  

Omar Nyabi, Mostafa Bentahir, Katrien Horré, An Herreman, Numa Gottardi-Littell, Christine Van Broeckhoven, Pascal Merchiers, Kurt Spittaels, Wim Annaert, and Bart De Strooper

Presenilins Mutated at Asp-257 or Asp-385 Restore Pen-2 Expression and Nicastrin Glycosylation but Remain Catalytically Inactive in the Absence of Wild Type Presenilin
J. Biol. Chem. 2003 278: 43430-43436. First Published on July 28, 2003; doi:10.1074/jbc.M306957200 [Abstract] [Full Text] [PDF]  

Kevin C. Miranda, Shannon R. Joseph, Alpha S. Yap, Rohan D. Teasdale, and Jennifer L. Stow

Contextual Binding of p120^ctn to E-cadherin at the Basolateral Plasma Membrane in Polarized Epithelia
J. Biol. Chem. 2003 278: 43480-43488. First Published on August 14, 2003; doi:10.1074/jbc.M305525200 [Abstract] [Full Text] [PDF]  

Savita Khanna, Sashwati Roy, Hoon Ryu, Praveen Bahadduri, Peter W. Swaan, Rajiv R. Ratan, and Chandan K. Sen

Molecular Basis of Vitamin E Action: TOCOTRIENOL MODULATES 12-LIPOXYGENASE, A KEY MEDIATOR OF GLUTAMATE-INDUCED NEURODEGENERATION
J. Biol. Chem. 2003 278: 43508-43515. First Published on August 13, 2003; doi:10.1074/jbc.M307075200 [Abstract] [Full Text] [PDF] Supplemental Data  

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Manipulation of Mouse Hematopoietic Progenitors by Specific Retroviral Infection
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Calcium Regulates ATP-sensitive Microtubule Binding by Chlamydomonas Outer Arm Dynein
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Novel Membrane Protein Containing Glycerophosphodiester Phosphodiesterase Motif Is Transiently Expressed during Osteoblast Differentiation
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Cloning, Expression, Characterization, and Role in Autocrine Cell Growth of Cell Surface Retention Sequence Binding Protein-1
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