Minireviews:

Vera Bianchi and Jozef Spychala

Mammalian 5'-Nucleotidases
J. Biol. Chem. 2003 278: 46195-46198. First Published on August 28, 2003; doi:10.1074/jbc.R300032200 [Full Text] [PDF]  

Accelerated Publications:

Einar M. Sigurdsson, David R. Brown, Muhammad A. Alim, Henrieta Scholtzova, Richard Carp, Harry C. Meeker, Frances Prelli, Blas Frangione, and Thomas Wisniewski

Copper Chelation Delays the Onset of Prion Disease
J. Biol. Chem. 2003 278: 46199-46202. First Published on September 30, 2003; doi:10.1074/jbc.C300303200 [Abstract] [Full Text] [PDF]  

DNA: Replication, Repair, and Recombination:

Mariarita De Felice, Luca Esposito, Biagio Pucci, Floriana Carpentieri, Mariarosaria De Falco, Mosè Rossi, and Francesca M. Pisani

Biochemical Characterization of a CDC6-like Protein from the Crenarchaeon Sulfolobus solfataricus
J. Biol. Chem. 2003 278: 46424-46431. First Published on September 8, 2003; doi:10.1074/jbc.M306075200 [Abstract] [Full Text] [PDF]  

Masaki Makise, Hitomi Takenaka, Wakako Kuwae, Naoko Takahashi, Tomofusa Tsuchiya, and Tohru Mizushima

Kinetics of ATP Binding to the Origin Recognition Complex of Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 46440-46445. First Published on September 8, 2003; doi:10.1074/jbc.M307392200 [Abstract] [Full Text] [PDF]  

Seong-Yun Jeong, Akiko Kumagai, Joon Lee, and William G. Dunphy

Phosphorylated Claspin Interacts with a Phosphate-binding Site in the Kinase Domain of Chk1 during ATR-mediated Activation
J. Biol. Chem. 2003 278: 46782-46788. First Published on September 8, 2003; doi:10.1074/jbc.M304551200 [Abstract] [Full Text] [PDF]  

Maureen E. Fitch, Satoshi Nakajima, Akira Yasui, and James M. Ford

In Vivo Recruitment of XPC to UV-induced Cyclobutane Pyrimidine Dimers by the DDB2 Gene Product
J. Biol. Chem. 2003 278: 46906-46910. First Published on August 27, 2003; doi:10.1074/jbc.M307254200 [Abstract] [Full Text] [PDF]  

Jiang-Cheng Shen and Lawrence A. Loeb

Mutations in the 8 Loop of Human APE1 Alter Binding and Cleavage of DNA Containing an Abasic Site
J. Biol. Chem. 2003 278: 46994-47001. First Published on September 8, 2003; doi:10.1074/jbc.M309362200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Florence Coulet, Sophie Nadaud, Monique Agrapart, and Florent Soubrier

Identification of Hypoxia-response Element in the Human Endothelial Nitric-oxide Synthase Gene Promoter
J. Biol. Chem. 2003 278: 46230-46240. First Published on September 8, 2003; doi:10.1074/jbc.M305420200 [Abstract] [Full Text] [PDF]  

Vincent van Pesch and Thomas Michiels

Characterization of Interferon- 13, a Novel Constitutive Murine Interferon- Subtype
J. Biol. Chem. 2003 278: 46321-46328. First Published on August 20, 2003; doi:10.1074/jbc.M302554200 [Abstract] [Full Text] [PDF] Supplemental Data  

Quynh-Giao V. Nguyen, Jean N. Buskin, Charis L. Himeda, Margaret A. Shield, and Stephen D. Hauschka

Differences in the Function of Three Conserved E-boxes of the Muscle Creatine Kinase Gene in Cultured Myocytes and in Transgenic Mouse Skeletal and Cardiac Muscle
J. Biol. Chem. 2003 278: 46494-46505. First Published on September 10, 2003; doi:10.1074/jbc.M308194200 [Abstract] [Full Text] [PDF]  

Mario Maira, Catherine Couture, Gwendal Le Martelot, Anne-Marie Pulichino, Steve Bilodeau, and Jacques Drouin

The T-box Factor Tpit Recruits SRC/p160 Co-activators and Mediates Hormone Action
J. Biol. Chem. 2003 278: 46523-46532. First Published on September 11, 2003; doi:10.1074/jbc.M305626200 [Abstract] [Full Text] [PDF]  

Patrick Viatour, Sylvie Legrand-Poels, Carine van Lint, Michael Warnier, Marie-Paule Merville, Jacques Gielen, Jacques Piette, Vincent Bours, and Alain Chariot

Cytoplasmic IB Increases NF-B-independent Transcription through Binding to Histone Deacetylase (HDAC) 1 and HDAC3
J. Biol. Chem. 2003 278: 46541-46548. First Published on September 12, 2003; doi:10.1074/jbc.M306381200 [Abstract] [Full Text] [PDF]  

Carmen Tellez, Marya McCarty, Maribelis Ruiz, and Menashe Bar-Eli

Loss of Activator Protein-2 Results in Overexpression of Protease-activated Receptor-1 and Correlates with the Malignant Phenotype of Human Melanoma
J. Biol. Chem. 2003 278: 46632-46642. First Published on September 15, 2003; doi:10.1074/jbc.M309159200 [Abstract] [Full Text] [PDF]  

Xiang-Qin Liu, Jing Yang, and Qing Meng

Four Inteins and Three Group II Introns Encoded in a Bacterial Ribonucleotide Reductase Gene
J. Biol. Chem. 2003 278: 46826-46831. First Published on September 15, 2003; doi:10.1074/jbc.M309575200 [Abstract] [Full Text] [PDF]  

Eungseok Kim, Shaozhen Xie, Shauh-Der Yeh, Yi-Fen Lee, Loretta L. Collins, Yueh-Chiang Hu, Chih-Rong Shyr, Xiao-Min Mu, Ning-Chun Liu, Yen-Ta Chen, Peng-Hui Wang, and Chawnshang Chang

Disruption of TR4 Orphan Nuclear Receptor Reduces the Expression of Liver Apolipoprotein E/C-I/C-II Gene Cluster
J. Biol. Chem. 2003 278: 46919-46926. First Published on September 3, 2003; doi:10.1074/jbc.M304088200 [Abstract] [Full Text] [PDF]  

Dianne C. Sullivan, Lucasz Huminiecki, John W. Moore, Joseph J. Boyle, Richard Poulsom, Daniel Creamer, Jonathan Barker, and Roy Bicknell

EndoPDI, a Novel Protein-disulfide Isomerase-like Protein That Is Preferentially Expressed in Endothelial Cells Acts as a Stress Survival Factor
J. Biol. Chem. 2003 278: 47079-47088. First Published on September 8, 2003; doi:10.1074/jbc.M308124200 [Abstract] [Full Text] [PDF]  

Huijun Zhi, Xiangdong Wang, Julio E. Cabrera, Reid C. Johnson, and Ding Jun Jin

Fis Stabilizes the Interaction between RNA Polymerase and the Ribosomal Promoter rrnB P1, Leading to Transcriptional Activation
J. Biol. Chem. 2003 278: 47340-47349. First Published on September 17, 2003; doi:10.1074/jbc.M305430200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Vladimir I. Martynov, Boris I. Maksimov, Natalya Y. Martynova, Alexey A. Pakhomov, Nadya G. Gurskaya, and Sergey A. Lukyanov

A Purple-blue Chromoprotein from Goniopora tenuidens Belongs to the DsRed Subfamily of GFP-like Proteins
J. Biol. Chem. 2003 278: 46288-46292. First Published on September 15, 2003; doi:10.1074/jbc.M306810200 [Abstract] [Full Text] [PDF]  

Eduardo O. Melo, Rafael Dhalia, Cezar Martins de Sa, Nancy Standart, and Osvaldo P. de Melo Neto

Identification of a C-terminal Poly(A)-binding Protein (PABP)-PABP Interaction Domain: ROLE IN COOPERATIVE BINDING TO POLY(A) AND EFFICIENT CAP DISTAL TRANSLATIONAL REPRESSION
J. Biol. Chem. 2003 278: 46357-46368. First Published on September 2, 2003; doi:10.1074/jbc.M307624200 [Abstract] [Full Text] [PDF]  

Michael Käser, Melanie Kambacheld, Brigitte Kisters-Woike, and Thomas Langer

Oma1, a Novel Membrane-bound Metallopeptidase in Mitochondria with Activities Overlapping with the m-AAA Protease
J. Biol. Chem. 2003 278: 46414-46423. First Published on September 8, 2003; doi:10.1074/jbc.M305584200 [Abstract] [Full Text] [PDF]  

Laura Sesma, Iñaki Alvarez, Miguel Marcilla, Alberto Paradela, and José A. López de Castro

Species-specific Differences in Proteasomal Processing and Tapasin-mediated Loading Influence Peptide Presentation by HLA-B27 in Murine Cells
J. Biol. Chem. 2003 278: 46461-46472. First Published on September 8, 2003; doi:10.1074/jbc.M308816200 [Abstract] [Full Text] [PDF]  

Jennifer Y. Lin and James A. DeCaprio

SV40 Large T Antigen Promotes Dephosphorylation of p130
J. Biol. Chem. 2003 278: 46482-46487. First Published on September 10, 2003; doi:10.1074/jbc.M307044200 [Abstract] [Full Text] [PDF]  

Paul A. Voziyan, Raja G. Khalifah, Christophe Thibaudeau, Alaattin Yildiz, Jaison Jacob, Anthony S. Serianni, and Billy G. Hudson

Modification of Proteins In Vitro by Physiological Levels of Glucose: PYRIDOXAMINE INHIBITS CONVERSION OF AMADORI INTERMEDIATE TO ADVANCED GLYCATION END-PRODUCTS THROUGH BINDING OF REDOX METAL IONS
J. Biol. Chem. 2003 278: 46616-46624. First Published on September 15, 2003; doi:10.1074/jbc.M307155200 [Abstract] [Full Text] [PDF]  

Elaine M. Majerus, Xinglong Zheng, Elodee A. Tuley, and J. Evan Sadler

Cleavage of the ADAMTS13 Propeptide Is Not Required for Protease Activity
J. Biol. Chem. 2003 278: 46643-46648. First Published on September 15, 2003; doi:10.1074/jbc.M309872200 [Abstract] [Full Text] [PDF] Supplemental Data  

Sung G. Lee and Vincent A. Fischetti

Presence of D-Alanine in an Endopeptidase from Streptococcus pyogenes
J. Biol. Chem. 2003 278: 46649-46653. First Published on September 16, 2003; doi:10.1074/jbc.M307378200 [Abstract] [Full Text] [PDF]  

Banafshé Larijani, Alistair N. Hume, Abul K. Tarafder, and Miguel C. Seabra

Multiple Factors Contribute to Inefficient Prenylation of Rab27a in Rab Prenylation Diseases
J. Biol. Chem. 2003 278: 46798-46804. First Published on August 25, 2003; doi:10.1074/jbc.M307799200 [Abstract] [Full Text] [PDF]  

Gert Zimmer, Michael Rohn, Gerard P. McGregor, Michael Schemann, Karl-Klaus Conzelmann, and Georg Herrler

Virokinin, a Bioactive Peptide of the Tachykinin Family, Is Released from the Fusion Protein of Bovine Respiratory Syncytial Virus
J. Biol. Chem. 2003 278: 46854-46861. First Published on September 2, 2003; doi:10.1074/jbc.M306949200 [Abstract] [Full Text] [PDF]  

Roberta Mancini, Markus Aebi, and Ari Helenius

Multiple Endoplasmic Reticulum-associated Pathways Degrade Mutant Yeast Carboxypeptidase Y in Mammalian Cells
J. Biol. Chem. 2003 278: 46895-46905. First Published on September 3, 2003; doi:10.1074/jbc.M302979200 [Abstract] [Full Text] [PDF]  

Mads Gravers Jeppesen, Pedro Ortiz, William Shepard, Terri Goss Kinzy, Jens Nyborg, and Gregers Rom Andersen

The Crystal Structure of the Glutathione S-Transferase-like Domain of Elongation Factor 1B from Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 47190-47198. First Published on September 12, 2003; doi:10.1074/jbc.M306630200 [Abstract] [Full Text] [PDF]  

Genomics, Proteomics, and Bioinformatics:

Orinda Chew, James Whelan, and A. Harvey Millar

Molecular Definition of the Ascorbate-Glutathione Cycle in Arabidopsis Mitochondria Reveals Dual Targeting of Antioxidant Defenses in Plants
J. Biol. Chem. 2003 278: 46869-46877. First Published on September 3, 2003; doi:10.1074/jbc.M307525200 [Abstract] [Full Text] [PDF] Supplemental Data  

Protein Structure and Folding:

Giovanni Gotte, Massimo Libonati, and Douglas V. Laurents

Glycosylation and Specific Deamidation of Ribonuclease B Affect the Formation of Three-dimensional Domain-swapped Oligomers
J. Biol. Chem. 2003 278: 46241-46251. First Published on September 8, 2003; doi:10.1074/jbc.M308470200 [Abstract] [Full Text] [PDF]  

Luisa Bracci, Chiara Falciani, Barbara Lelli, Luisa Lozzi, Ylenia Runci, Alessandro Pini, Maria Graziella De Montis, Alessandro Tagliamonte, and Paolo Neri

Synthetic Peptides in the Form of Dendrimers Become Resistant to Protease Activity
J. Biol. Chem. 2003 278: 46590-46595. First Published on September 12, 2003; doi:10.1074/jbc.M308615200 [Abstract] [Full Text] [PDF]  

Mihaela Necula, Carmen N. Chirita, and Jeff Kuret

Rapid Anionic Micelle-mediated -Synuclein Fibrillization in Vitro
J. Biol. Chem. 2003 278: 46674-46680. First Published on September 23, 2003; doi:10.1074/jbc.M308231200 [Abstract] [Full Text] [PDF]  

David W. Keizer, Peter J. West, Erinna F. Lee, Doju Yoshikami, Baldomero M. Olivera, Grzegorz Bulaj, and Raymond S. Norton

Structural Basis for Tetrodotoxin-resistant Sodium Channel Binding by µ-Conotoxin SmIIIA
J. Biol. Chem. 2003 278: 46805-46813. First Published on September 10, 2003; doi:10.1074/jbc.M309222200 [Abstract] [Full Text] [PDF] Supplemental Data  

Francisco N. Barrera, José A. Poveda, José M. González-Ros, and José L. Neira

Binding of the C-terminal Sterile Motif (SAM) Domain of Human p73 to Lipid Membranes
J. Biol. Chem. 2003 278: 46878-46885. First Published on September 3, 2003; doi:10.1074/jbc.M307846200 [Abstract] [Full Text] [PDF]  

Emilia Ortiz-Salmerón, Marzia Nuccetelli, Aaron J. Oakley, Michael W. Parker, Mario Lo Bello, and Luis García-Fuentes

Thermodynamic Description of the Effect of the Mutation Y49F on Human Glutathione Transferase P1-1 in Binding with Glutathione and the Inhibitor S-Hexylglutathione
J. Biol. Chem. 2003 278: 46938-46948. First Published on August 23, 2003; doi:10.1074/jbc.M305043200 [Abstract] [Full Text] [PDF]  

Aruna Sathyamurthy, Mark D. Allen, Alexey G. Murzin, and Mark Bycroft

Crystal Structure of the Malignant Brain Tumor (MBT) Repeats in Sex Comb on Midleg-like 2 (SCML2)
J. Biol. Chem. 2003 278: 46968-46973. First Published on September 1, 2003; doi:10.1074/jbc.M306469200 [Abstract] [Full Text] [PDF]  

Christine Gaboriaud, Jordi Juanhuix, Arnaud Gruez, Monique Lacroix, Claudine Darnault, David Pignol, Denis Verger, Juan C. Fontecilla-Camps, and Gérard J. Arlaud

The Crystal Structure of the Globular Head of Complement Protein C1q Provides a Basis for Its Versatile Recognition Properties
J. Biol. Chem. 2003 278: 46974-46982. First Published on September 5, 2003; doi:10.1074/jbc.M307764200 [Abstract] [Full Text] [PDF]  

Masanori Yagi, Kazumasa Sakurai, Chitkala Kalidas, Carl A. Batt, and Yuji Goto

Reversible Unfolding of Bovine -Lactoglobulin Mutants without a Free Thiol Group
J. Biol. Chem. 2003 278: 47009-47015. First Published on September 8, 2003; doi:10.1074/jbc.M308592200 [Abstract] [Full Text] [PDF]  

Takeshi Chiba, Yoshihisa Hagihara, Takashi Higurashi, Kazuhiro Hasegawa, Hironobu Naiki, and Yuji Goto

Amyloid Fibril Formation in the Context of Full-length Protein: EFFECTS OF PROLINE MUTATIONS ON THE AMYLOID FIBRIL FORMATION OF ₂-MICROGLOBULIN
J. Biol. Chem. 2003 278: 47016-47024. First Published on September 4, 2003; doi:10.1074/jbc.M304473200 [Abstract] [Full Text] [PDF]  

Eric M. Bennett, Chenglong Li, Paula W. Allan, William B. Parker, and Steven E. Ealick

Structural Basis for Substrate Specificity of Escherichia coli Purine Nucleoside Phosphorylase
J. Biol. Chem. 2003 278: 47110-47118. First Published on August 21, 2003; doi:10.1074/jbc.M304622200 [Abstract] [Full Text] [PDF]  

John O. Trent, Zi-xuan Wang, James L. Murray, Wenhai Shao, Hirokazu Tamamura, Nobutaka Fujii, and Stephen C. Peiper

Lipid Bilayer Simulations of CXCR4 with Inverse Agonists and Weak Partial Agonists
J. Biol. Chem. 2003 278: 47136-47144. First Published on September 4, 2003; doi:10.1074/jbc.M307850200 [Abstract] [Full Text] [PDF]  

Jason T. Maynes, Craig Garen, Maia M. Cherney, Gerald Newton, Dorit Arad, Yossef Av-Gay, Robert C. Fahey, and Michael N. G. James

The Crystal Structure of 1-D-myo-Inosityl 2-Acetamido-2-deoxy--D-glucopyranoside Deacetylase (MshB) from Mycobacterium tuberculosis Reveals a Zinc Hydrolase with a Lactate Dehydrogenase Fold
J. Biol. Chem. 2003 278: 47166-47170. First Published on September 4, 2003; doi:10.1074/jbc.M308914200 [Abstract] [Full Text] [PDF]  

Julie Allouch, Murielle Jam, William Helbert, Tristan Barbeyron, Bernard Kloareg, Bernard Henrissat, and Mirjam Czjzek

The Three-dimensional Structures of Two -Agarases
J. Biol. Chem. 2003 278: 47171-47180. First Published on September 11, 2003; doi:10.1074/jbc.M308313200 [Abstract] [Full Text] [PDF]  

Esben Lorentzen, Ehmke Pohl, Peter Zwart, Alexander Stark, Robert B. Russell, Thomas Knura, Reinhard Hensel, and Bettina Siebers

Crystal Structure of an Archaeal Class I Aldolase and the Evolution of ()₈ Barrel Proteins
J. Biol. Chem. 2003 278: 47253-47260. First Published on August 26, 2003; doi:10.1074/jbc.M305922200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Heide Schmidt and R. Luise Krauth-Siegel

Functional and Physicochemical Characterization of the Thioredoxin System in Trypanosoma brucei
J. Biol. Chem. 2003 278: 46329-46336. First Published on August 29, 2003; doi:10.1074/jbc.M305338200 [Abstract] [Full Text] [PDF]  

Jennifer A. Fraser, Pushpa Kansagra, Claire Kotecki, Robert D. C. Saunders, and Lesley I. McLellan

The Modifier Subunit of Drosophila Glutamate-Cysteine Ligase Regulates Catalytic Activity by Covalent and Noncovalent Interactions and Influences Glutathione Homeostasis in Vivo
J. Biol. Chem. 2003 278: 46369-46377. First Published on September 3, 2003; doi:10.1074/jbc.M308035200 [Abstract] [Full Text] [PDF]  

Vasantha P. Mutucumarana, Francine Acher, David L. Straight, Da-Yun Jin, and Darrel W. Stafford

A Conserved Region of Human Vitamin K-dependent Carboxylase between Residues 393 and 404 Is Important for Its Interaction with the Glutamate Substrate
J. Biol. Chem. 2003 278: 46488-46493. First Published on September 10, 2003; doi:10.1074/jbc.M307707200 [Abstract] [Full Text] [PDF]  

Yifei Zhu, Yang Wang, Maureen J. Gorman, Haobo Jiang, and Michael R. Kanost

Manduca sexta Serpin-3 Regulates Prophenoloxidase Activation in Response to Infection by Inhibiting Prophenoloxidase-activating Proteinases
J. Biol. Chem. 2003 278: 46556-46564. First Published on September 9, 2003; doi:10.1074/jbc.M309682200 [Abstract] [Full Text] [PDF]  

Daniela Breckau, Esther Mahlitz, Anselm Sauerwald, Gunhild Layer, and Dieter Jahn

Oxygen-dependent Coproporphyrinogen III Oxidase (HemF) from Escherichia coli Is Stimulated by Manganese
J. Biol. Chem. 2003 278: 46625-46631. First Published on September 15, 2003; doi:10.1074/jbc.M308553200 [Abstract] [Full Text] [PDF]  

Chin-Chuan Wei, Zhi-Qiang Wang, Craig Hemann, Russ Hille, and Dennis J. Stuehr

A Tetrahydrobiopterin Radical Forms and then Becomes Reduced during N-Hydroxyarginine Oxidation by Nitric-oxide Synthase
J. Biol. Chem. 2003 278: 46668-46673. First Published on September 22, 2003; doi:10.1074/jbc.M307682200 [Abstract] [Full Text] [PDF]  

Chun Guo and Lucia Piacentini

Type I Collagen-induced MMP-2 Activation Coincides with Up-regulation of Membrane Type 1-Matrix Metalloproteinase and TIMP-2 in Cardiac Fibroblasts
J. Biol. Chem. 2003 278: 46699-46708. First Published on September 11, 2003; doi:10.1074/jbc.M307238200 [Abstract] [Full Text] [PDF]  

Olena Pylypenko, Francesca Vitali, Katja Zerbe, John A. Robinson, and Ilme Schlichting

Crystal Structure of OxyC, a Cytochrome P450 Implicated in an Oxidative C–C Coupling Reaction during Vancomycin Biosynthesis
J. Biol. Chem. 2003 278: 46727-46733. First Published on July 29, 2003; doi:10.1074/jbc.M306486200 [Abstract] [Full Text] [PDF]  

Huey-Chun Huang, Guey-Yueh Shi, Shinn-Jong Jiang, Chung-Sheng Shi, Chun-Mei Wu, Hsi-Yuan Yang, and Hua-Lin Wu

Thrombomodulin-mediated Cell Adhesion: INVOLVEMENT OF ITS LECTIN-LIKE DOMAIN
J. Biol. Chem. 2003 278: 46750-46759. First Published on September 1, 2003; doi:10.1074/jbc.M305216200 [Abstract] [Full Text] [PDF]  

Lynn E. Bretscher, Huiying Li, Thomas L. Poulos, and Owen W. Griffith

Structural Characterization and Kinetics of Nitric-oxide Synthase Inhibition by Novel N⁵-(Iminoalkyl)- and N⁵-(Iminoalkenyl)-ornithines
J. Biol. Chem. 2003 278: 46789-46797. First Published on September 5, 2003; doi:10.1074/jbc.M306787200 [Abstract] [Full Text] [PDF]  

Michael K. Swan, J. T. Graham Solomons, Craig C. Beeson, Thomas Hansen, Peter Schönheit, and Christopher Davies

Structural Evidence for a Hydride Transfer Mechanism of Catalysis in Phosphoglucose Isomerase from Pyrococcus furiosus
J. Biol. Chem. 2003 278: 47261-47268. First Published on September 11, 2003; doi:10.1074/jbc.M308603200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Enika Nagababu, Somasundaram Ramasamy, Darrell R. Abernethy, and Joseph M. Rifkind

Active Nitric Oxide Produced in the Red Cell under Hypoxic Conditions by Deoxyhemoglobin-mediated Nitrite Reduction
J. Biol. Chem. 2003 278: 46349-46356. First Published on September 2, 2003; doi:10.1074/jbc.M307572200 [Abstract] [Full Text] [PDF]  

Frank Petrat, Sandra Paluch, Elke Dogruöz, Petra Dörfler, Michael Kirsch, Hans-Gert Korth, Reiner Sustmann, and Herbert de Groot

Reduction of Fe(III) Ions Complexed to Physiological Ligands by Lipoyl Dehydrogenase and Other Flavoenzymes in Vitro: IMPLICATIONS FOR AN ENZYMATIC REDUCTION OF Fe(III) IONS OF THE LABILE IRON POOL
J. Biol. Chem. 2003 278: 46403-46413. First Published on September 8, 2003; doi:10.1074/jbc.M305291200 [Abstract] [Full Text] [PDF]  

M. Jyothi Kumar, David G. Nicholls, and Julie K. Andersen

Oxidative -Ketoglutarate Dehydrogenase Inhibition via Subtle Elevations in Monoamine Oxidase B Levels Results in Loss of Spare Respiratory Capacity: IMPLICATIONS FOR PARKINSON'S DISEASE
J. Biol. Chem. 2003 278: 46432-46439. First Published on September 8, 2003; doi:10.1074/jbc.M306378200 [Abstract] [Full Text] [PDF]  

Eliane Fischer and Uwe Sauer

A Novel Metabolic Cycle Catalyzes Glucose Oxidation and Anaplerosis in Hungry Escherichia coli
J. Biol. Chem. 2003 278: 46446-46451. First Published on September 8, 2003; doi:10.1074/jbc.M307968200 [Abstract] [Full Text] [PDF]  

Paul H. Bernardo, Nicola Brasch, Christina L. L. Chai, and Paul Waring

A Novel Redox Mechanism for the Glutathione-dependent Reversible Uptake of a Fungal Toxin in Cells
J. Biol. Chem. 2003 278: 46549-46555. First Published on August 28, 2003; doi:10.1074/jbc.M304825200 [Abstract] [Full Text] [PDF]  

Mark E. Drew, James C. Morris, Zefeng Wang, Lance Wells, Marco Sanchez, Scott M. Landfear, and Paul T. Englund

The Adenosine Analog Tubercidin Inhibits Glycolysis in Trypanosoma brucei as Revealed by an RNA Interference Library
J. Biol. Chem. 2003 278: 46596-46600. First Published on September 12, 2003; doi:10.1074/jbc.M309320200 [Abstract] [Full Text] [PDF]  

Kazuhiko Takahashi, Shinji Mizuarai, Hiromitsu Araki, Satoshi Mashiko, Akane Ishihara, Akio Kanatani, Hiraku Itadani, and Hidehito Kotani

Adiposity Elevates Plasma MCP-1 Levels Leading to the Increased CD11b-positive Monocytes in Mice
J. Biol. Chem. 2003 278: 46654-46660. First Published on September 16, 2003; doi:10.1074/jbc.M309895200 [Abstract] [Full Text] [PDF]  

Oliver Maneg, Bernd Ludwig, and Francesco Malatesta

Different Interaction Modes of Two Cytochrome-c Oxidase Soluble Cu_A Fragments with Their Substrates
J. Biol. Chem. 2003 278: 46734-46740. First Published on August 23, 2003; doi:10.1074/jbc.M307594200 [Abstract] [Full Text] [PDF]  

Heike Witt, Enrica Bordignon, Donatella Carbonera, Jan P. Dekker, Navassard Karapetyan, Christian Teutloff, Andrew Webber, Wolfgang Lubitz, and Eberhard Schlodder

Species-specific Differences of the Spectroscopic Properties of P700: ANALYSIS OF THE INFLUENCE OF NON-CONSERVED AMINO ACID RESIDUES BY SITE-DIRECTED MUTAGENESIS OF PHOTOSYSTEM I FROM CHLAMYDOMONAS REINHARDTII
J. Biol. Chem. 2003 278: 46760-46771. First Published on August 21, 2003; doi:10.1074/jbc.M304776200 [Abstract] [Full Text] [PDF]  

Toshiharu Suzuki, Tomoe Murakami, Ryota Iino, Junko Suzuki, Sakurako Ono, Yasuo Shirakihara, and Masasuke Yoshida

F₀F₁-ATPase/Synthase Is Geared to the Synthesis Mode by Conformational Rearrangement of Subunit in Response to Proton Motive Force and ADP/ATP Balance
J. Biol. Chem. 2003 278: 46840-46846. First Published on July 24, 2003; doi:10.1074/jbc.M307165200 [Abstract] [Full Text] [PDF]  

Jeng-Jer Shieh, Chi-Jiunn Pan, Brian C. Mansfield, and Janice Yang Chou

A Glucose-6-phosphate Hydrolase, Widely Expressed Outside the Liver, Can Explain Age-dependent Resolution of Hypoglycemia in Glycogen Storage Disease Type Ia
J. Biol. Chem. 2003 278: 47098-47103. First Published on September 16, 2003; doi:10.1074/jbc.M309472200 [Abstract] [Full Text] [PDF]  

Limei H. Jones, Aimin Liu, and Victor L. Davidson

An Engineered Cu_A Amicyanin Capable of Intermolecular Electron Transfer Reactions
J. Biol. Chem. 2003 278: 47269-47274. First Published on September 11, 2003; doi:10.1074/jbc.M308863200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Noriko Suzuki, Kay-Hooi Khoo, Chin-Mei Chen, Hao-Chia Chen, and Yuan C. Lee

N-Glycan Structures of Pigeon IgG: A MAJOR SERUM GLYCOPROTEIN CONTAINING Gal1–4Gal TERMINI
J. Biol. Chem. 2003 278: 46293-46306. First Published on September 9, 2003; doi:10.1074/jbc.M307132200 [Abstract] [Full Text] [PDF] Supplemental Data  

Catherine Robbe, Calliope Capon, Emmanuel Maes, Monique Rousset, Alain Zweibaum, Jean-Pierre Zanetta, and Jean-Claude Michalski

Evidence of Regio-specific Glycosylation in Human Intestinal Mucins: PRESENCE OF AN ACIDIC GRADIENT ALONG THE INTESTINAL TRACT
J. Biol. Chem. 2003 278: 46337-46348. First Published on September 2, 2003; doi:10.1074/jbc.M302529200 [Abstract] [Full Text] [PDF]  

Thomas Hellmark, Lanlin Chen, Sophie Ohlsson, Jörgen Wieslander, and Warren Kline Bolton

Point Mutations of Single Amino Acids Abolish Ability of ₃ NC1 Domain to Elicit Experimental Autoimmune Glomerulonephritis in Rats
J. Biol. Chem. 2003 278: 46516-46522. First Published on September 11, 2003; doi:10.1074/jbc.M211951200 [Abstract] [Full Text] [PDF]  

Kyle J. McQuade and Alan C. Rapraeger

Syndecan-1 Transmembrane and Extracellular Domains Have Unique and Distinct Roles in Cell Spreading
J. Biol. Chem. 2003 278: 46607-46615. First Published on September 14, 2003; doi:10.1074/jbc.M304775200 [Abstract] [Full Text] [PDF] Supplemental Data  

Mattias Belting, Katrin Mani, Mats Jönsson, Fang Cheng, Staffan Sandgren, Susanne Jonsson, Kan Ding, Jean-Guy Delcros, and Lars-Åke Fransson

Glypican-1 Is a Vehicle for Polyamine Uptake in Mammalian Cells: A PIVOTAL ROLE FOR NITROSOTHIOL-DERIVED NITRIC OXIDE
J. Biol. Chem. 2003 278: 47181-47189. First Published on September 11, 2003; doi:10.1074/jbc.M308325200 [Abstract] [Full Text] [PDF]  

Alana K. Majors, Richard C. Austin, Carol A. de la Motte, Reed E. Pyeritz, Vincent C. Hascall, Sean P. Kessler, Ganes Sen, and Scott A. Strong

Endoplasmic Reticulum Stress Induces Hyaluronan Deposition and Leukocyte Adhesion
J. Biol. Chem. 2003 278: 47223-47231. First Published on September 3, 2003; doi:10.1074/jbc.M304871200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Zhengtong Pei, Nadia A. Oey, Maartje M. Zuidervaart, Zhenzhen Jia, Yuanyuan Li, Steven J. Steinberg, Kirby D. Smith, and Paul A. Watkins

The Acyl-CoA Synthetase "Bubblegum" (Lipidosin): FURTHER CHARACTERIZATION AND ROLE IN NEURONAL FATTY ACID -OXIDATION
J. Biol. Chem. 2003 278: 47070-47078. First Published on September 15, 2003; doi:10.1074/jbc.M310075200 [Abstract] [Full Text] [PDF]  

Qian Zhang, Hai Kee Chieu, Choon Pei Low, Shaochong Zhang, Chew Kiat Heng, and Hongyuan Yang

Schizosaccharomyces pombe Cells Deficient in Triacylglycerols Synthesis Undergo Apoptosis upon Entry into the Stationary Phase
J. Biol. Chem. 2003 278: 47145-47155. First Published on September 8, 2003; doi:10.1074/jbc.M306998200 [Abstract] [Full Text] [PDF]  

Mingsheng Wang, Yiliang E. Liu, Itzhak D. Goldberg, and Y. Eric Shi

Induction of Mammary Gland Differentiation in Transgenic Mice by the Fatty Acid-binding Protein MRG
J. Biol. Chem. 2003 278: 47319-47325. First Published on September 15, 2003; doi:10.1074/jbc.M308131200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Rubén Vicente, Artur Escalada, Mireia Coma, Gemma Fuster, Ester Sánchez-Tilló, Carmen López-Iglesias, Concepció Soler, Carles Solsona, Antonio Celada, and Antonio Felipe

Differential Voltage-dependent K⁺ Channel Responses during Proliferation and Activation in Macrophages
J. Biol. Chem. 2003 278: 46307-46320. First Published on August 15, 2003; doi:10.1074/jbc.M304388200 [Abstract] [Full Text] [PDF]  

Tsuyoshi Nishi, Shoko Kawasaki-Nishi, and Michael Forgac

Expression and Function of the Mouse V-ATPase d Subunit Isoforms
J. Biol. Chem. 2003 278: 46396-46402. First Published on September 8, 2003; doi:10.1074/jbc.M303924200 [Abstract] [Full Text] [PDF]  

Daniela V. Rial, Jorgelina Ottado, and Eduardo A. Ceccarelli

Precursors with Altered Affinity for Hsp70 in Their Transit Peptides Are Efficiently Imported into Chloroplasts
J. Biol. Chem. 2003 278: 46473-46481. First Published on September 10, 2003; doi:10.1074/jbc.M306684200 [Abstract] [Full Text] [PDF]  

U. Subrahmanyeswara Rao and Shanthy L. Nuti

Identification of Two Different States of P-glycoprotein in Its Catalytic Cycle: ROLE OF THE LINKER REGION IN THE TRANSITION BETWEEN THESE TWO STATES
J. Biol. Chem. 2003 278: 46576-46582. First Published on September 10, 2003; doi:10.1074/jbc.M308078200 [Abstract] [Full Text] [PDF]  

Frédéric Bard, Laetitia Mazelin, Christine Péchoux-Longin, Vivek Malhotra, and Pierre Jurdic

Src Regulates Golgi Structure and KDEL Receptor-dependent Retrograde Transport to the Endoplasmic Reticulum
J. Biol. Chem. 2003 278: 46601-46606. First Published on September 15, 2003; doi:10.1074/jbc.M302221200 [Abstract] [Full Text] [PDF]  

Michihiro Tateyama, Ilaria Rivolta, Colleen E. Clancy, and Robert S. Kass

Modulation of Cardiac Sodium Channel Gating by Protein Kinase A Can Be Altered by Disease-linked Mutation
J. Biol. Chem. 2003 278: 46718-46726. First Published on September 18, 2003; doi:10.1074/jbc.M308977200 [Abstract] [Full Text] [PDF]  

Richard Lundmark and Sven R. Carlsson

Sorting Nexin 9 Participates in Clathrin-mediated Endocytosis through Interactions with the Core Components
J. Biol. Chem. 2003 278: 46772-46781. First Published on September 2, 2003; doi:10.1074/jbc.M307334200 [Abstract] [Full Text] [PDF]  

Cédric Orelle, Olivier Dalmas, Philippe Gros, Attilio Di Pietro, and Jean-Michel Jault

The Conserved Glutamate Residue Adjacent to the Walker-B Motif Is the Catalytic Base for ATP Hydrolysis in the ATP-binding Cassette Transporter BmrA
J. Biol. Chem. 2003 278: 47002-47008. First Published on September 10, 2003; doi:10.1074/jbc.M308268200 [Abstract] [Full Text] [PDF]  

David Godreau, Roger Vranckx, Ange Maguy, Catherine Goyenvalle, and Stéphane N. Hatem

Different Isoforms of Synapse-associated Protein, SAP97, Are Expressed in the Heart and Have Distinct Effects on the Voltage-gated K⁺ Channel Kv1.5
J. Biol. Chem. 2003 278: 47046-47052. First Published on September 10, 2003; doi:10.1074/jbc.M308463200 [Abstract] [Full Text] [PDF]  

Guangyu Wu, Guiqing Zhao, and Youe He

Distinct Pathways for the Trafficking of Angiotensin II and Adrenergic Receptors from the Endoplasmic Reticulum to the Cell Surface: Rab1-INDEPENDENT TRANSPORT OF A G PROTEIN-COUPLED RECEPTOR
J. Biol. Chem. 2003 278: 47062-47069. First Published on September 11, 2003; doi:10.1074/jbc.M305707200 [Abstract] [Full Text] [PDF]  

Li Yan Qiu, Jan B. Koenderink, Herman G. P. Swarts, Peter H. G. M. Willems, and Jan Joep H. H. M. De Pont

Phe⁷⁸³, Thr⁷⁹⁷, and Asp⁸⁰⁴ in Transmembrane Hairpin M5-M6 of Na⁺,K⁺-ATPase Play a Key Role in Ouabain Binding
J. Biol. Chem. 2003 278: 47240-47244. First Published on September 12, 2003; doi:10.1074/jbc.M308833200 [Abstract] [Full Text] [PDF]  

Zhenyu Zhang, Colleen Charsky, Patricia M. Kane, and Stephan Wilkens

Yeast V₁-ATPase: AFFINITY PURIFICATION AND STRUCTURAL FEATURES BY ELECTRON MICROSCOPY
J. Biol. Chem. 2003 278: 47299-47306. First Published on September 5, 2003; doi:10.1074/jbc.M309445200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Liat Fux, Anat Nussbaum-Shochat, and Orna Amster-Choder

Interactions between the PTS Regulation domains of the BglG Transcriptional Antiterminator from Escherichia coli
J. Biol. Chem. 2003 278: 46203-46209. First Published on August 15, 2003; doi:10.1074/jbc.M306506200 [Abstract] [Full Text] [PDF]  

Jia Yu, Barbara Leibiger, Shao-Nian Yang, James J. Caffery, Stephen B. Shears, Ingo B. Leibiger, Christopher J. Barker, and Per-Olof Berggren

Cytosolic Multiple Inositol Polyphosphate Phosphatase in the Regulation of Cytoplasmic Free Ca²⁺ Concentration
J. Biol. Chem. 2003 278: 46210-46218. First Published on September 8, 2003; doi:10.1074/jbc.M303743200 [Abstract] [Full Text] [PDF]  

Boris Görke

Regulation of the Escherichia coli Antiterminator Protein BglG by Phosphorylation at Multiple Sites and Evidence for Transfer of Phosphoryl Groups between Monomers
J. Biol. Chem. 2003 278: 46219-46229. First Published on September 8, 2003; doi:10.1074/jbc.M308002200 [Abstract] [Full Text] [PDF] Supplemental Data  

Philip L. Fisette, Sanjay Ram, Jorunn M. Andersen, Wen Guo, and Robin R. Ingalls

The Lip Lipoprotein from Neisseria gonorrhoeae Stimulates Cytokine Release and NF-B Activation in Epithelial Cells in a Toll-like Receptor 2-dependent Manner
J. Biol. Chem. 2003 278: 46252-46260. First Published on September 9, 2003; doi:10.1074/jbc.M306587200 [Abstract] [Full Text] [PDF]  

Olivia S. Gardner, Brian J. Dewar, H. Shelton Earp, James M. Samet, and Lee M. Graves

Dependence of Peroxisome Proliferator-activated Receptor Ligand-induced Mitogen-activated Protein Kinase Signaling on Epidermal Growth Factor Receptor Transactivation
J. Biol. Chem. 2003 278: 46261-46269. First Published on September 9, 2003; doi:10.1074/jbc.M307827200 [Abstract] [Full Text] [PDF]  

Mu-Lan He, Arturo E. Gonzalez-Iglesias, and Stanko S. Stojilkovic

Role of Nucleotide P2 Receptors in Calcium Signaling and Prolactin Release in Pituitary Lactotrophs
J. Biol. Chem. 2003 278: 46270-46277. First Published on September 11, 2003; doi:10.1074/jbc.M309005200 [Abstract] [Full Text] [PDF]  

Lidija Klampfer, Jie Huang, Georgia Corner, John Mariadason, Diego Arango, Takehiko Sasazuki, Senji Shirasawa, and Leonard Augenlicht

Oncogenic Ki-Ras Inhibits the Expression of Interferon-responsive Genes through Inhibition of STAT1 and STAT2 Expression
J. Biol. Chem. 2003 278: 46278-46287. First Published on September 12, 2003; doi:10.1074/jbc.M304721200 [Abstract] [Full Text] [PDF]  

Brenda J. Irvin, Lauren D. Wood, Lilin Wang, Randy Fenrick, Courtney G. Sansam, Graham Packham, Michael Kinch, Elizabeth Yang, and Scott W. Hiebert

TEL, a Putative Tumor Suppressor, Induces Apoptosis and Represses Transcription of Bcl-X_L
J. Biol. Chem. 2003 278: 46378-46386. First Published on September 5, 2003; doi:10.1074/jbc.M305189200 [Abstract] [Full Text] [PDF]  

Ana Olivera, Hans M. Rosenfeldt, Meryem Bektas, Fang Wang, Isao Ishii, Jerold Chun, Sheldon Milstien, and Sarah Spiegel

Sphingosine Kinase Type 1 Induces G_12/13-mediated Stress Fiber Formation, yet Promotes Growth and Survival Independent of G Protein-coupled Receptors
J. Biol. Chem. 2003 278: 46452-46460. First Published on September 8, 2003; doi:10.1074/jbc.M308749200 [Abstract] [Full Text] [PDF]  

Nan Hao, Necmettin Yildirim, Yuqi Wang, Timothy C. Elston, and Henrik G. Dohlman

Regulators of G Protein Signaling and Transient Activation of Signaling: EXPERIMENTAL AND COMPUTATIONAL ANALYSIS REVEALS NEGATIVE AND POSITIVE FEEDBACK CONTROLS ON G PROTEIN ACTIVITY
J. Biol. Chem. 2003 278: 46506-46515. First Published on September 10, 2003; doi:10.1074/jbc.M308432200 [Abstract] [Full Text] [PDF]  

Naohito Saito, Gilles Courtois, Ayako Chiba, Norio Yamamoto, Takeshi Nitta, Noriko Hironaka, Martin Rowe, Naoki Yamamoto, and Shoji Yamaoka

Two Carboxyl-terminal Activation Regions of Epstein-Barr Virus Latent Membrane Protein 1 Activate NF-B through Distinct Signaling Pathways in Fibroblast Cell Lines
J. Biol. Chem. 2003 278: 46565-46575. First Published on September 10, 2003; doi:10.1074/jbc.M302549200 [Abstract] [Full Text] [PDF]  

Xiang-Qun Hu, Li Zhang, Randall R. Stewart, and Forrest F. Weight

Arginine 222 in the Pre-transmembrane Domain 1 of 5-HT_3A Receptors Links Agonist Binding to Channel Gating
J. Biol. Chem. 2003 278: 46583-46589. First Published on September 11, 2003; doi:10.1074/jbc.M308974200 [Abstract] [Full Text] [PDF]  

Emese Toth-Zsamboki, Cécile Oury, Heidi Cornelissen, Rita De Vos, Jos Vermylen, and Marc F Hoylaerts

P2X₁-mediated ERK2 Activation Amplifies the Collagen-induced Platelet Secretion by Enhancing Myosin Light Chain Kinase Activation
J. Biol. Chem. 2003 278: 46661-46667. First Published on September 18, 2003; doi:10.1074/jbc.M308452200 [Abstract] [Full Text] [PDF]  

Mayada El-Mousawi, Lioudmila Tchistiakova, Ludmila Yurchenko, Grzegorz Pietrzynski, Maria Moreno, Danica Stanimirovic, Darakhshan Ahmad, and Valery Alakhov

A Vascular Endothelial Growth Factor High Affinity Receptor 1-specific Peptide with Antiangiogenic Activity Identified Using a Phage Display Peptide Library
J. Biol. Chem. 2003 278: 46681-46691. First Published on September 2, 2003; doi:10.1074/jbc.M308681200 [Abstract] [Full Text] [PDF]  

Minji Jo, Keena S. Thomas, Lihua Wu, and Steven L. Gonias

Soluble Urokinase-type Plasminogen Activator Receptor Inhibits Cancer Cell Growth and Invasion by Direct Urokinase-independent Effects on Cell Signaling
J. Biol. Chem. 2003 278: 46692-46698. First Published on September 8, 2003; doi:10.1074/jbc.M308808200 [Abstract] [Full Text] [PDF]  

Penelope L. Moore, Sarah Ong, and Tim J. Harrison

Squamous Cell Carcinoma Antigen 1-mediated Binding of Hepatitis B Virus to Hepatocytes Does Not Involve the Hepatic Serpin Clearance System
J. Biol. Chem. 2003 278: 46709-46717. First Published on September 15, 2003; doi:10.1074/jbc.M302842200 [Abstract] [Full Text] [PDF]  

Meritxell Canals, Daniel Marcellino, Francesca Fanelli, Francisco Ciruela, Piero de Benedetti, Steven R. Goldberg, Kim Neve, Kjell Fuxe, Luigi F. Agnati, Amina S. Woods, Sergi Ferré, Carme Lluis, Michel Bouvier, and Rafael Franco

Adenosine A_2A-Dopamine D₂ Receptor-Receptor Heteromerization: QUALITATIVE AND QUANTITATIVE ASSESSMENT BY FLUORESCENCE AND BIOLUMINESCENCE ENERGY TRANSFER
J. Biol. Chem. 2003 278: 46741-46749. First Published on August 21, 2003; doi:10.1074/jbc.M306451200 [Abstract] [Full Text] [PDF] Supplemental Data  

Maria Julia Marinissen, Joan-Marc Servitja, Stefan Offermanns, Melvin I. Simon, and J. Silvio Gutkind

Thrombin Protease-activated Receptor-1 Signals through G_q- and G₁₃-initiated MAPK Cascades Regulating c-Jun Expression to Induce Cell Transformation
J. Biol. Chem. 2003 278: 46814-46825. First Published on September 3, 2003; doi:10.1074/jbc.M305709200 [Abstract] [Full Text] [PDF]  

Nobuaki Igarashi, Taro Okada, Shun Hayashi, Toshitada Fujita, Saleem Jahangeer, and Shun-ichi Nakamura

Sphingosine Kinase 2 Is a Nuclear Protein and Inhibits DNA Synthesis
J. Biol. Chem. 2003 278: 46832-46839. First Published on September 2, 2003; doi:10.1074/jbc.M306577200 [Abstract] [Full Text] [PDF] Supplemental Data  

Maria F. Gomez, Laura V. Gonzalez Bosc, Andra S. Stevenson, M. Keith Wilkerson, David C. Hill-Eubanks, and Mark T. Nelson

Constitutively Elevated Nuclear Export Activity Opposes Ca²⁺-dependent NFATc3 Nuclear Accumulation in Vascular Smooth Muscle: ROLE OF JNK2 AND Crm-1
J. Biol. Chem. 2003 278: 46847-46853. First Published on September 3, 2003; doi:10.1074/jbc.M304765200 [Abstract] [Full Text] [PDF]  

Eddy S. Yang and Kerry L. Burnstein

Vitamin D Inhibits G₁ to S Progression in LNCaP Prostate Cancer Cells through p27^Kip1 Stabilization and Cdk2 Mislocalization to the Cytoplasm
J. Biol. Chem. 2003 278: 46862-46868. First Published on September 3, 2003; doi:10.1074/jbc.M306340200 [Abstract] [Full Text] [PDF]  

Bharath Ananthanarayanan, Robert V. Stahelin, Michelle A. Digman, and Wonhwa Cho

Activation Mechanisms of Conventional Protein Kinase C Isoforms Are Determined by the Ligand Affinity and Conformational Flexibility of Their C1 Domains
J. Biol. Chem. 2003 278: 46886-46894. First Published on September 3, 2003; doi:10.1074/jbc.M307853200 [Abstract] [Full Text] [PDF]  

Maya F. Kotturi, Douglas A. Carlow, Junella C. Lee, Hermann J. Ziltener, and Wilfred A. Jefferies

Identification and Functional Characterization of Voltage-dependent Calcium Channels in T Lymphocytes
J. Biol. Chem. 2003 278: 46949-46960. First Published on September 3, 2003; doi:10.1074/jbc.M309268200 [Abstract] [Full Text] [PDF]  

Baoguang Han, Zizheng Dong, and Jian-Ting Zhang

Tight Control of Platelet-derived Growth Factor B/c-sis Expression by Interplay between the 5'-Untranslated Region Sequence and the Major Upstream Promoter
J. Biol. Chem. 2003 278: 46983-46993. First Published on September 5, 2003; doi:10.1074/jbc.M304976200 [Abstract] [Full Text] [PDF]  

Robert P. Mohney, Margaret Das, Trever G. Bivona, Richard Hanes, Anthony G. Adams, Mark R. Philips, and John P. O'Bryan

Intersectin Activates Ras but Stimulates Transcription through an Independent Pathway Involving JNK
J. Biol. Chem. 2003 278: 47038-47045. First Published on September 11, 2003; doi:10.1074/jbc.M303895200 [Abstract] [Full Text] [PDF]  

Venugopalan D. Nair and Stuart C. Sealfon

Agonist-specific Transactivation of Phosphoinositide 3-Kinase Signaling Pathway Mediated by the Dopamine D₂ Receptor
J. Biol. Chem. 2003 278: 47053-47061. First Published on September 11, 2003; doi:10.1074/jbc.M303364200 [Abstract] [Full Text] [PDF]  

Padma L. Channavajhala, Leeying Wu, John W. Cuozzo, J. Perry Hall, Wei Liu, Lih-Ling Lin, and Yuhua Zhang

Identification of a Novel Human Kinase Supporter of Ras (hKSR-2) That Functions as a Negative Regulator of Cot (Tpl2) Signaling
J. Biol. Chem. 2003 278: 47089-47097. First Published on September 15, 2003; doi:10.1074/jbc.M306002200 [Abstract] [Full Text] [PDF]  

Sashwati Roy, Savita Khanna, William A. Wallace, Jani Lappalainen, Cameron Rink, Arturo J. Cardounel, Jay L. Zweier, and Chandan K. Sen

Characterization of Perceived Hyperoxia in Isolated Primary Cardiac Fibroblasts and in the Reoxygenated Heart
J. Biol. Chem. 2003 278: 47129-47135. First Published on September 2, 2003; doi:10.1074/jbc.M308703200 [Abstract] [Full Text] [PDF] Supplemental Data  

Guang Yu, Hongyu Luo, Yulian Wu, and Jiangping Wu

Mouse EphrinB3 Augments T-cell Signaling and Responses to T-cell Receptor Ligation
J. Biol. Chem. 2003 278: 47209-47216. First Published on September 17, 2003; doi:10.1074/jbc.M306659200 [Abstract] [Full Text] [PDF]  

Jae J. Song and Yong J. Lee

Role of the ASK1-SEK1-JNK1-HIPK1 Signal in Daxx Trafficking and ASK1 Oligomerization
J. Biol. Chem. 2003 278: 47245-47252. First Published on September 10, 2003; doi:10.1074/jbc.M213201200 [Abstract] [Full Text] [PDF]  

Susanne Roelle, Robert Grosse, Achim Aigner, H. W. Krell, Frank Czubayko, and Thomas Gudermann

Matrix Metalloproteinases 2 and 9 Mediate Epidermal Growth Factor Receptor Transactivation by Gonadotropin-releasing Hormone
J. Biol. Chem. 2003 278: 47307-47318. First Published on September 8, 2003; doi:10.1074/jbc.M304377200 [Abstract] [Full Text] [PDF]  

Xue Wei Meng, Joya Chandra, David Loegering, Keri Van Becelaere, Timothy J. Kottke, Steven D. Gore, Judith E. Karp, Judy Sebolt-Leopold, and Scott H. Kaufmann

Central Role of Fas-associated Death Domain Protein in Apoptosis Induction by the Mitogen-activated Protein Kinase Kinase Inhibitor CI-1040 (PD184352) in Acute Lymphocytic Leukemia Cells in Vitro
J. Biol. Chem. 2003 278: 47326-47339. First Published on September 8, 2003; doi:10.1074/jbc.M304793200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Shoji Fukusumi, Hiromi Yoshida, Ryo Fujii, Minoru Maruyama, Hidetoshi Komatsu, Yugo Habata, Yasushi Shintani, Shuji Hinuma, and Masahiko Fujino

A New Peptidic Ligand and Its Receptor Regulating Adrenal Function in Rats
J. Biol. Chem. 2003 278: 46387-46395. First Published on September 5, 2003; doi:10.1074/jbc.M305270200 [Abstract] [Full Text] [PDF] Supplemental Data  

Gary S. Goldberg, David B. Alexander, Patricia Pellicena, Zhong-Yin Zhang, Hiroyuki Tsuda, and W. Todd Miller

Src Phosphorylates Cas on Tyrosine 253 to Promote Migration of Transformed Cells
J. Biol. Chem. 2003 278: 46533-46540. First Published on September 11, 2003; doi:10.1074/jbc.M307526200 [Abstract] [Full Text] [PDF]  

Cherry Wongtrakool, Sarah Malpel, Julie Gorenstein, Jeff Sedita, Maria I. Ramirez, T. Michael Underhill, and Wellington V. Cardoso

Down-regulation of Retinoic Acid Receptor Signaling Is Required for Sacculation and Type I Cell Formation in the Developing Lung
J. Biol. Chem. 2003 278: 46911-46918. First Published on August 28, 2003; doi:10.1074/jbc.M307977200 [Abstract] [Full Text] [PDF]  

Blessing Crimeen-Irwin, Sarah Ellis, Dale Christiansen, Mandy J. Ludford-Menting, Julie Milland, Marc Lanteri, Bruce E. Loveland, Denis Gerlier, and Sarah M. Russell

Ligand Binding Determines Whether CD46 Is Internalized by Clathrin-coated Pits or Macropinocytosis
J. Biol. Chem. 2003 278: 46927-46937. First Published on September 3, 2003; doi:10.1074/jbc.M308261200 [Abstract] [Full Text] [PDF]  

Rutilio A. Fratti, Jennifer Chua, and Vojo Deretic

Induction of p38 Mitogen-activated Protein Kinase Reduces Early Endosome Autoantigen 1 (EEA1) Recruitment to Phagosomal Membranes
J. Biol. Chem. 2003 278: 46961-46967. First Published on September 8, 2003; doi:10.1074/jbc.M305225200 [Abstract] [Full Text] [PDF]  

Ju-Hyun Lee, Kwok-Fai Lau, Michael S. Perkinton, Claire L. Standen, Stephen J. A. Shemilt, Luc Mercken, Jonathan D. Cooper, Declan M. McLoughlin, and Christopher C. J. Miller

The Neuronal Adaptor Protein X11 Reduces A Levels in the Brains of Alzheimer's APPswe Tg2576 Transgenic Mice
J. Biol. Chem. 2003 278: 47025-47029. First Published on September 11, 2003; doi:10.1074/jbc.M300503200 [Abstract] [Full Text] [PDF]  

Ping Wang, Chih-Tien Wang, Jihong Bai, Meyer B. Jackson, and Edwin R. Chapman

Mutations in the Effector Binding Loops in the C2A and C2B Domains of Synaptotagmin I Disrupt Exocytosis in a Nonadditive Manner
J. Biol. Chem. 2003 278: 47030-47037. First Published on September 8, 2003; doi:10.1074/jbc.M306728200 [Abstract] [Full Text] [PDF]  

R. Andrea DeYoung, Julie C. Baker, Dragana Cado, and Astar Winoto

The Orphan Steroid Receptor Nur77 Family Member Nor-1 Is Essential for Early Mouse Embryogenesis
J. Biol. Chem. 2003 278: 47104-47109. First Published on September 16, 2003; doi:10.1074/jbc.M307496200 [Abstract] [Full Text] [PDF]  

Kate van der Giessen, Sergio Di-Marco, Eveline Clair, and Imed Eddine Gallouzi

RNAi-mediated HuR Depletion Leads to the Inhibition of Muscle Cell Differentiation
J. Biol. Chem. 2003 278: 47119-47128. First Published on August 27, 2003; doi:10.1074/jbc.M308889200 [Abstract] [Full Text] [PDF]  

Natasha Y. Frank, Shona S. Pendse, Peter H. Lapchak, Armen Margaryan, Debbie Shlain, Carsten Doeing, Mohamed H. Sayegh, and Markus H. Frank

Regulation of Progenitor Cell Fusion by ABCB5 P-glycoprotein, a Novel Human ATP-binding Cassette Transporter
J. Biol. Chem. 2003 278: 47156-47165. First Published on September 7, 2003; doi:10.1074/jbc.M308700200 [Abstract] [Full Text] [PDF]  

Konstanze F. Winklhofer, Iris H. Henn, Penelope C. Kay-Jackson, Ulrich Heller, and Jörg Tatzelt

Inactivation of Parkin by Oxidative Stress and C-terminal Truncations: A PROTECTIVE ROLE OF MOLECULAR CHAPERONES
J. Biol. Chem. 2003 278: 47199-47208. First Published on September 12, 2003; doi:10.1074/jbc.M306769200 [Abstract] [Full Text] [PDF]  

Tohru Ikeda, Michiyuki Kasai, Junko Suzuki, Hiroyuki Kuroyama, Sachiko Seki, Masanori Utsuyama, and Katsuiku Hirokawa

Multimerization of the Receptor Activator of Nuclear Factor-B Ligand (RANKL) Isoforms and Regulation of Osteoclastogenesis
J. Biol. Chem. 2003 278: 47217-47222. First Published on September 17, 2003; doi:10.1074/jbc.M304636200 [Abstract] [Full Text] [PDF]  

Yuzhi Jia, Chao Qi, Zhongyi Zhang, Takashi Hashimoto, M. Sambasiva Rao, Steven Huyghe, Yasuyuki Suzuki, Paul P. Van Veldhoven, Myriam Baes, and Janardan K. Reddy

Overexpression of Peroxisome Proliferator-activated Receptor- (PPAR)-regulated Genes in Liver in the Absence of Peroxisome Proliferation in Mice Deficient in both L- and D-Forms of Enoyl-CoA Hydratase/Dehydrogenase Enzymes of Peroxisomal -Oxidation System
J. Biol. Chem. 2003 278: 47232-47239. First Published on September 18, 2003; doi:10.1074/jbc.M306363200 [Abstract] [Full Text] [PDF]  

Hiroki Yokota, Mary B. Goldring, and Hui Bin Sun

CITED2-mediated Regulation of MMP-1 and MMP-13 in Human Chondrocytes under Flow Shear
J. Biol. Chem. 2003 278: 47275-47280. First Published on September 5, 2003; doi:10.1074/jbc.M304652200 [Abstract] [Full Text] [PDF]  

Teresa Sanchez, Tatiana Estrada-Hernandez, Ji-Hye Paik, Ming-Tao Wu, Krishnan Venkataraman, Volker Brinkmann, Kevin Claffey, and Timothy Hla

Phosphorylation and Action of the Immunomodulator FTY720 Inhibits Vascular Endothelial Cell Growth Factor-induced Vascular Permeability
J. Biol. Chem. 2003 278: 47281-47290. First Published on September 3, 2003; doi:10.1074/jbc.M306896200 [Abstract] [Full Text] [PDF]  

Jinah Hwang, Aniket Saha, Yong Chool Boo, George P. Sorescu, J. Scott McNally, Steven M. Holland, Sergei Dikalov, Don P. Giddens, Kathy K. Griendling, David G. Harrison, and Hanjoong Jo

Oscillatory Shear Stress Stimulates Endothelial Production of O₂^- from p47^phox-dependent NAD(P)H Oxidases, Leading to Monocyte Adhesion
J. Biol. Chem. 2003 278: 47291-47298. First Published on September 4, 2003; doi:10.1074/jbc.M305150200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Beatrice Cobucci-Ponzano, Antonio Trincone, Assunta Giordano, Mosè Rossi, and Marco Moracci

Identification of an archaeal -L-fucosidase encoded by an interrupted gene. Production of a functional enzyme by mutations micking programmed -1 frameshifting. Vol. 278 (2003) 14622–14631
J. Biol. Chem. 2003 278: 47350. [Full Text] [PDF]  

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