JBC INTERFERin siRNA transfection reagent

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 Table of Contents: Nov 28 2003; 278 (48)   [Index by Author]  [Cover Figure and Caption]
       Reflections
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Reflections:

Maxine Singer
Leon Heppel and the Early Days of RNA Biochemistry
J. Biol. Chem. 2003 278: 47351-47356. First Published on September 15, 2003; doi:10.1074/jbc.X300008200 [Full Text] [PDF]  

Accelerated Publications:

Joshua Z. Rappoport, Bushra W. Taha, Simone Lemeer, Alexandre Benmerah, and Sanford M. Simon
The AP-2 Complex Is Excluded from the Dynamic Population of Plasma Membrane-associated Clathrin
J. Biol. Chem. 2003 278: 47357-47360. First Published on October 6, 2003; doi:10.1074/jbc.C300390200 [Abstract] [Full Text] [PDF] Supplemental DataSupplemental Data  

Hyun Ae Woo, Sang Won Kang, Hyung Ki Kim, Kap-Seok Yang, Ho Zoon Chae, and Sue Goo Rhee
Reversible Oxidation of the Active Site Cysteine of Peroxiredoxins to Cysteine Sulfinic Acid: IMMUNOBLOT DETECTION WITH ANTIBODIES SPECIFIC FOR THE HYPEROXIDIZED CYSTEINE-CONTAINING SEQUENCE
J. Biol. Chem. 2003 278: 47361-47364. First Published on October 14, 2003; doi:10.1074/jbc.C300428200 [Abstract] [Full Text] [PDF]  

DNA: Replication, Repair, and Recombination:

Jana Kasparkova, Olga Novakova, Victoria Marini, Yousef Najajreh, Dan Gibson, Jose-Manuel Perez, and Viktor Brabec
Activation of Trans Geometry in Bifunctional Mononuclear Platinum Complexes by a Piperidine Ligand: MECHANISTIC STUDIES ON ANTITUMOR ACTION
J. Biol. Chem. 2003 278: 47516-47525. First Published on September 10, 2003; doi:10.1074/jbc.M304720200 [Abstract] [Full Text] [PDF] Supplemental Data  

Antony R. Parker, Robert N. O'Meally, Fikret Sahin, Gloria H. Su, Frederick K. Racke, William G. Nelson, Theodore L. DeWeese, and James R. Eshleman
Defective Human MutY Phosphorylation Exists in Colorectal Cancer Cell Lines with Wild-type MutY Alleles
J. Biol. Chem. 2003 278: 47937-47945. First Published on September 9, 2003; doi:10.1074/jbc.M306598200 [Abstract] [Full Text] [PDF]  

Chunyang Cao, Keehwan Kwon, Yu Lin Jiang, Alexander C. Drohat, and James T. Stivers
Solution Structure and Base Perturbation Studies Reveal a Novel Mode of Alkylated Base Recognition by 3-Methyladenine DNA Glycosylase I
J. Biol. Chem. 2003 278: 48012-48020. First Published on September 16, 2003; doi:10.1074/jbc.M307500200 [Abstract] [Full Text] [PDF]  

Jeremy P. Braybrooke, Ji-Liang Li, Leonard Wu, Fiona Caple, Fiona E. Benson, and Ian D. Hickson
Functional Interaction between the Bloom's Syndrome Helicase and the RAD51 Paralog, RAD51L3 (RAD51D)
J. Biol. Chem. 2003 278: 48357-48366. First Published on September 15, 2003; doi:10.1074/jbc.M308838200 [Abstract] [Full Text] [PDF]  

Anil Munshi, Dominique Cannella, Howard Brickner, Isabelle Salles-Passador, Vladimir Podust, Rati Fotedar, and Arun Fotedar
Cell Cycle-dependent Phosphorylation of the Large Subunit of Replication Factor C (RF-C) Leads to Its Dissociation from the RF-C Complex
J. Biol. Chem. 2003 278: 48467-48473. First Published on August 28, 2003; doi:10.1074/jbc.M309349200 [Abstract] [Full Text] [PDF]  

Molly E. Shea and Hiroshi Hiasa
The RuvAB Branch Migration Complex Can Displace Topoisomerase IV·Quinolone·DNA Ternary Complexes
J. Biol. Chem. 2003 278: 48485-48490. First Published on September 17, 2003; doi:10.1074/jbc.M304217200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Guangming Xiong, Hans-Jörg Martin, and Edmund Maser
Identification and Characterization of a Novel Translational Repressor of the Steroid-inducible 3{alpha}-Hydroxysteroid Dehydrogenase/Carbonyl Reductase Gene in Comamonas testosteroni
J. Biol. Chem. 2003 278: 47400-47407. First Published on September 15, 2003; doi:10.1074/jbc.M309210200 [Abstract] [Full Text] [PDF]  

Pavan Adiseshaiah, Srinivas R. Papaiahgari, Hue Vuong, Dhananjaya V. Kalvakolanu, and Sekhar P. Reddy
Multiple cis-Elements Mediate the Transcriptional Activation of Human fra-1 by 12-O-Tetradecanoylphorbol-13-acetate in Bronchial Epithelial Cells
J. Biol. Chem. 2003 278: 47423-47433. First Published on September 17, 2003; doi:10.1074/jbc.M303505200 [Abstract] [Full Text] [PDF]  

Mehtap Bali, Bin Zhang, Kevin A. Morano, and Corinne A. Michels
The Hsp90 Molecular Chaperone Complex Regulates Maltose Induction and Stability of the Saccharomyces MAL Gene Transcription Activator Mal63p
J. Biol. Chem. 2003 278: 47441-47448. First Published on September 18, 2003; doi:10.1074/jbc.M309536200 [Abstract] [Full Text] [PDF]  

Sang Do Lee, Emanuela Colla, Mee Rie Sheen, Ki Young Na, and H. Moo Kwon
Multiple Domains of TonEBP Cooperate to Stimulate Transcription in Response to Hypertonicity
J. Biol. Chem. 2003 278: 47571-47577. First Published on September 11, 2003; doi:10.1074/jbc.M308795200 [Abstract] [Full Text] [PDF]  

Hong Ruan, Mary Jane Zarnowski, Samuel W. Cushman, and Harvey F. Lodish
Standard Isolation of Primary Adipose Cells from Mouse Epididymal Fat Pads Induces Inflammatory Mediators and Down-regulates Adipocyte Genes
J. Biol. Chem. 2003 278: 47585-47593. First Published on September 15, 2003; doi:10.1074/jbc.M305257200 [Abstract] [Full Text] [PDF]  

Naveen Babbar, Natalia A. Ignatenko, Robert A. Casero, Jr., and Eugene W. Gerner
Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer
J. Biol. Chem. 2003 278: 47762-47775. First Published on September 23, 2003; doi:10.1074/jbc.M307265200 [Abstract] [Full Text] [PDF]  

YuFeng Lu, Inna Goldenberg, Ling Bei, Jelena Andrejic, and Elizabeth A. Eklund
HoxA10 Represses Gene Transcription in Undifferentiated Myeloid Cells by Interaction with Histone Deacetylase 2
J. Biol. Chem. 2003 278: 47792-47802. First Published on September 25, 2003; doi:10.1074/jbc.M305885200 [Abstract] [Full Text] [PDF]  

Ying Zhu, Xiu-Ling Cai, Zong-Yang Wang, and Meng-Min Hong
An Interaction between a MYC Protein and an EREBP Protein Is Involved in Transcriptional Regulation of the Rice Wx Gene
J. Biol. Chem. 2003 278: 47803-47811. First Published on August 28, 2003; doi:10.1074/jbc.M302806200 [Abstract] [Full Text] [PDF]  

Rüdiger J. Blaschke, Christine Töpfer, Antonio Marchini, Herbert Steinbeisser, Johannes W. G. Janssen, and Gudrun A. Rappold
Transcriptional and Translational Regulation of the Léri-Weill and Turner Syndrome Homeobox Gene SHOX
J. Biol. Chem. 2003 278: 47820-47826. First Published on September 5, 2003; doi:10.1074/jbc.M306685200 [Abstract] [Full Text] [PDF]  

Meeyul Hwang and Maria I. Morasso
The Novel Murine Ca2+-binding Protein, Scarf, Is Differentially Expressed during Epidermal Differentiation
J. Biol. Chem. 2003 278: 47827-47833. First Published on September 11, 2003; doi:10.1074/jbc.M306561200 [Abstract] [Full Text] [PDF]  

Yan Liu, Sanjay Sinha, and Gary Owens
A Transforming Growth Factor-{beta} Control Element Required for SM {alpha}-Actin Expression in Vivo Also Partially Mediates GKLF-dependent Transcriptional Repression
J. Biol. Chem. 2003 278: 48004-48011. First Published on September 10, 2003; doi:10.1074/jbc.M301902200 [Abstract] [Full Text] [PDF]  

Hao Zhou, Ken M. Cadigan, and Dennis J. Thiele
A Copper-regulated Transporter Required for Copper Acquisition, Pigmentation, and Specific Stages of Development in Drosophila melanogaster
J. Biol. Chem. 2003 278: 48210-48218. First Published on September 8, 2003; doi:10.1074/jbc.M309820200 [Abstract] [Full Text] [PDF]  

Anton Meinhart, Jascha Blobel, and Patrick Cramer
An Extended Winged Helix Domain in General Transcription Factor E/IIE{alpha}
J. Biol. Chem. 2003 278: 48267-48274. First Published on September 17, 2003; doi:10.1074/jbc.M307874200 [Abstract] [Full Text] [PDF]  

RNA: Structure, Metabolism, and Catalysis:

Mizuki Takenaka and Axel Brennicke
In Vitro RNA Editing in Pea Mitochondria Requires NTP or dNTP, Suggesting Involvement of an RNA Helicase
J. Biol. Chem. 2003 278: 47526-47533. First Published on September 10, 2003; doi:10.1074/jbc.M305341200 [Abstract] [Full Text] [PDF]  

Saheli Chowdhury, Curdin Ragaz, Emma Kreuger, and Franz Narberhaus
Temperature-controlled Structural Alterations of an RNA Thermometer
J. Biol. Chem. 2003 278: 47915-47921. First Published on September 8, 2003; doi:10.1074/jbc.M306874200 [Abstract] [Full Text] [PDF]  

Kazuma Aoki, Ken Matsumoto, and Masafumi Tsujimoto
Xenopus Cold-inducible RNA-binding Protein 2 Interacts with ElrA, the Xenopus Homolog of HuR, and Inhibits Deadenylation of Specific mRNAs
J. Biol. Chem. 2003 278: 48491-48497. First Published on September 17, 2003; doi:10.1074/jbc.M308328200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Suzanne L. Fleck, Berry Birdsall, Jeffrey Babon, Anton R. Dluzewski, Stephen R. Martin, William D. Morgan, Evelina Angov, Catherine A. Kettleborough, James Feeney, Michael J. Blackman, and Anthony A. Holder
Suramin and Suramin Analogues Inhibit Merozoite Surface Protein-1 Secondary Processing and Erythrocyte Invasion by the Malaria Parasite Plasmodium falciparum
J. Biol. Chem. 2003 278: 47670-47677. First Published on September 17, 2003; doi:10.1074/jbc.M306603200 [Abstract] [Full Text] [PDF]  

Melissa N. Holowaty, Yi Sheng, Tin Nguyen, Cheryl Arrowsmith, and Lori Frappier
Protein Interaction Domains of the Ubiquitin-specific Protease, USP7/HAUSP
J. Biol. Chem. 2003 278: 47753-47761. First Published on September 23, 2003; doi:10.1074/jbc.M307200200 [Abstract] [Full Text] [PDF]  

Nina Jendreyko, Mikhail Popkov, Roger R. Beerli, Junho Chung, Dorian B. McGavern, Christoph Rader, and Carlos F. Barbas, III
Intradiabodies, Bispecific, Tetravalent Antibodies for the Simultaneous Functional Knockout of Two Cell Surface Receptors
J. Biol. Chem. 2003 278: 47812-47819. First Published on August 28, 2003; doi:10.1074/jbc.M307002200 [Abstract] [Full Text] [PDF] Supplemental Data  

Brigitte Poppenberger, Franz Berthiller, Doris Lucyshyn, Tobias Sieberer, Rainer Schuhmacher, Rudolf Krska, Karl Kuchler, Josef Glössl, Christian Luschnig, and Gerhard Adam
Detoxification of the Fusarium Mycotoxin Deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana
J. Biol. Chem. 2003 278: 47905-47914. First Published on September 11, 2003; doi:10.1074/jbc.M307552200 [Abstract] [Full Text] [PDF]  

Surafel Mulugeta and Michael F. Beers
Processing of Surfactant Protein C Requires a Type II Transmembrane Topology Directed by Juxtamembrane Positively Charged Residues
J. Biol. Chem. 2003 278: 47979-47986. First Published on August 21, 2003; doi:10.1074/jbc.M308210200 [Abstract] [Full Text] [PDF]  

Marcin Cieslak, Jacek Szymanski, Ryszard W. Adamiak, and Czeslaw S. Cierniewski
Structural Rearrangements of the 10–23 DNAzyme to {beta}3 Integrin Subunit mRNA Induced by Cations and Their Relations to the Catalytic Activity
J. Biol. Chem. 2003 278: 47987-47996. First Published on September 2, 2003; doi:10.1074/jbc.M300504200 [Abstract] [Full Text] [PDF]  

Michael C. Kiel, V. Samuel Raj, Hideko Kaji, and Akira Kaji
Release of Ribosome-bound Ribosome Recycling Factor by Elongation Factor G
J. Biol. Chem. 2003 278: 48041-48050. First Published on September 5, 2003; doi:10.1074/jbc.M304834200 [Abstract] [Full Text] [PDF]  

Aaron C. Pawlyk, Benoit I. Giasson, Deepak M. Sampathu, Francisco A. Perez, Kah Leong Lim, Valina L. Dawson, Ted M. Dawson, Richard D. Palmiter, John Q. Trojanowski, and Virginia M.-Y. Lee
Novel Monoclonal Antibodies Demonstrate Biochemical Variation of Brain Parkin with Age
J. Biol. Chem. 2003 278: 48120-48128. First Published on September 12, 2003; doi:10.1074/jbc.M306889200 [Abstract] [Full Text] [PDF]  

Andrew P. Hibbert, Stephen J. Morris, Nabil G. Seidah, and Richard A. Murphy
Neurotrophin-4, Alone or Heterodimerized with Brain-derived Neurotrophic Factor, Is Sorted to the Constitutive Secretory Pathway
J. Biol. Chem. 2003 278: 48129-48136. First Published on September 11, 2003; doi:10.1074/jbc.M300961200 [Abstract] [Full Text] [PDF]  

Denis J. Dupré, Zhangguo Chen, Christian Le Gouill, Caroline Thériault, Jean-Luc Parent, Marek Rola-Pleszczynski, and Jana Stankova
Trafficking, Ubiquitination, and Down-regulation of the Human Platelet-activating Factor Receptor
J. Biol. Chem. 2003 278: 48228-48235. First Published on September 18, 2003; doi:10.1074/jbc.M304082200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Alberto Lleó, Oksana Berezovska, Pavan Ramdya, Hiroaki Fukumoto, Susan Raju, Tejal Shah, and Bradley T. Hyman
Notch1 Competes with the Amyloid Precursor Protein for {gamma}-Secretase and Down-regulates Presenilin-1 Gene Expression
J. Biol. Chem. 2003 278: 47370-47375. First Published on September 5, 2003; doi:10.1074/jbc.M308480200 [Abstract] [Full Text] [PDF]  

Christina Bak Pedersen, Peter Bross, Vibeke Stenbroen Winter, Thomas Juhl Corydon, Lars Bolund, Kim Bartlett, Jerry Vockley, and Niels Gregersen
Misfolding, Degradation, and Aggregation of Variant Proteins: THE MOLECULAR PATHOGENESIS OF SHORT CHAIN ACYL-CoA DEHYDROGENASE (SCAD) DEFICIENCY
J. Biol. Chem. 2003 278: 47449-47458. First Published on September 23, 2003; doi:10.1074/jbc.M309514200 [Abstract] [Full Text] [PDF]  

Jaap Broos, Edi Gabellieri, Gijs I. van Boxel, J. Baz Jackson, and Giovanni B. Strambini
Tryptophan Phosphorescence Spectroscopy Reveals That a Domain in the NAD(H)-binding Component (dI) of Transhydrogenase from Rhodospirillum rubrum Has an Extremely Rigid and Conformationally Homogeneous Protein Core
J. Biol. Chem. 2003 278: 47578-47584. First Published on September 12, 2003; doi:10.1074/jbc.M309287200 [Abstract] [Full Text] [PDF]  

Young Jun Im, Jun Hyuck Lee, Seong Ho Park, Soo Jeong Park, Seong-Hwan Rho, Gil Bu Kang, Eunjoon Kim, and Soo Hyun Eom
Crystal Structure of the Shank PDZ-Ligand Complex Reveals a Class I PDZ Interaction and a Novel PDZ-PDZ Dimerization
J. Biol. Chem. 2003 278: 48099-48104. First Published on September 3, 2003; doi:10.1074/jbc.M306919200 [Abstract] [Full Text] [PDF]  

Mario Salmona, Michela Morbin, Tania Massignan, Laura Colombo, Giulia Mazzoleni, Raffaella Capobianco, Luisa Diomede, Florian Thaler, Luca Mollica, Giovanna Musco, Joseph J. Kourie, Orso Bugiani, Deepak Sharma, Hideyo Inouye, Daniel A. Kirschner, Gianluigi Forloni, and Fabrizio Tagliavini
Structural Properties of Gerstmann-Sträussler-Scheinker Disease Amyloid Protein
J. Biol. Chem. 2003 278: 48146-48153. First Published on September 11, 2003; doi:10.1074/jbc.M307295200 [Abstract] [Full Text] [PDF]  

Tomonori Kaneko, Takashi Kumasaka, Tadashi Ganbe, Takao Sato, Keiji Miyazawa, Naomi Kitamura, and Nobuo Tanaka
Structural Insight into Modest Binding of a Non-PXXP Ligand to the Signal Transducing Adaptor Molecule-2 Src Homology 3 Domain
J. Biol. Chem. 2003 278: 48162-48168. First Published on September 16, 2003; doi:10.1074/jbc.M306677200 [Abstract] [Full Text] [PDF]  

Ling Lu, Michael E. Lamm, Hongmin Li, Blaise Corthesy, and Jing-Ren Zhang
The Human Polymeric Immunoglobulin Receptor Binds to Streptococcus pneumoniae via Domains 3 and 4
J. Biol. Chem. 2003 278: 48178-48187. First Published on September 17, 2003; doi:10.1074/jbc.M306906200 [Abstract] [Full Text] [PDF]  

Ulf Göransson and David J. Craik
Disulfide Mapping of the Cyclotide Kalata B1: CHEMICAL PROOF OF THE CYCLIC CYSTINE KNOT MOTIF
J. Biol. Chem. 2003 278: 48188-48196. First Published on September 5, 2003; doi:10.1074/jbc.M308771200 [Abstract] [Full Text] [PDF]  

Michel J. Perron, Grant E. Blouse, and Joseph D. Shore
Distortion of the Catalytic Domain of Tissue-type Plasminogen Activator by Plasminogen Activator Inhibitor-1 Coincides with the Formation of Stable Serpin-Proteinase Complexes
J. Biol. Chem. 2003 278: 48197-48203. First Published on September 18, 2003; doi:10.1074/jbc.M306184200 [Abstract] [Full Text] [PDF]  

Magnus S. Alphey, Roderick A. M. Williams, Jeremy C. Mottram, Graham H. Coombs, and William N. Hunter
The Crystal Structure of Leishmania major 3-Mercaptopyruvate Sulfurtransferase: A THREE-DOMAIN ARCHITECTURE WITH A SERINE PROTEASE-LIKE TRIAD AT THE ACTIVE SITE
J. Biol. Chem. 2003 278: 48219-48227. First Published on September 1, 2003; doi:10.1074/jbc.M307187200 [Abstract] [Full Text] [PDF]  

Christian Siebold, Ingrid Arnold, Luis F. Garcia-Alles, Ulrich Baumann, and Bernhard Erni
Crystal Structure of the Citrobacter freundii Dihydroxyacetone Kinase Reveals an Eight-stranded {alpha}-Helical Barrel ATP-binding Domain
J. Biol. Chem. 2003 278: 48236-48244. First Published on September 9, 2003; doi:10.1074/jbc.M305942200 [Abstract] [Full Text] [PDF]  

Maoqing Dong, Zhijun Li, Mengwei Zang, Delia I. Pinon, Terry P. Lybrand, and Laurence J. Miller
Spatial Approximation between Two Residues in the Mid-region of Secretin and the Amino Terminus of Its Receptor: INCORPORATION OF SEVEN SETS OF SUCH CONSTRAINTS INTO A THREE-DIMENSIONAL MODEL OF THE AGONIST-BOUND SECRETIN RECEPTOR
J. Biol. Chem. 2003 278: 48300-48312. First Published on September 18, 2003; doi:10.1074/jbc.M309166200 [Abstract] [Full Text] [PDF]  

Kuo-Kuang Wen and Peter A. Rubenstein
Biochemical Consequences of the Cardiofunk (R177H) Mutation in Yeast Actin
J. Biol. Chem. 2003 278: 48386-48394. First Published on September 16, 2003; doi:10.1074/jbc.M308980200 [Abstract] [Full Text] [PDF]  

Claire Senay, Paul Ferrari, Corinne Rocher, Klaus-Jörg Rieger, Jacques Winter, Denis Platel, and Yves Bourne
The Mtr2-Mex67 NTF2-like Domain Complex: STRUCTURAL INSIGHTS INTO A DUAL ROLE OF Mtr2 FOR YEAST NUCLEAR EXPORT
J. Biol. Chem. 2003 278: 48395-48403. First Published on September 22, 2003; doi:10.1074/jbc.M308275200 [Abstract] [Full Text] [PDF]  

J. Craig Forrest, Jacquelyn A. Campbell, Pierre Schelling, Thilo Stehle, and Terence S. Dermody
Structure-Function Analysis of Reovirus Binding to Junctional Adhesion Molecule 1: IMPLICATIONS FOR THE MECHANISM OF REOVIRUS ATTACHMENT
J. Biol. Chem. 2003 278: 48434-48444. First Published on September 9, 2003; doi:10.1074/jbc.M305649200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Chris A. Tarling, Shouming He, Gerlind Sulzenbacher, Christophe Bignon, Yves Bourne, Bernard Henrissat, and Stephen G. Withers
Identification of the Catalytic Nucleophile of the Family 29 {alpha}-L-Fucosidase from Thermotoga maritima through Trapping of a Covalent Glycosyl-Enzyme Intermediate and Mutagenesis
J. Biol. Chem. 2003 278: 47394-47399. First Published on September 15, 2003; doi:10.1074/jbc.M306610200 [Abstract] [Full Text] [PDF]  

Kazuharu Takeuchi, Akimasa Hatanaka, Meiko Kimura, Nobuo Seki, Ikuo Kimura, Shoichi Yamada, and Shinya Yamashita
Aspolin, a Novel Extremely Aspartic Acid-rich Protein in Fish Muscle, Promotes Iron-mediated Demethylation of Trimethylamine-N-oxide
J. Biol. Chem. 2003 278: 47416-47422. First Published on September 16, 2003; doi:10.1074/jbc.M309415200 [Abstract] [Full Text] [PDF]  

Beata A. Wolucka and Marc Van Montagu
GDP-Mannose 3',5'-Epimerase Forms GDP-L-gulose, a Putative Intermediate for the de Novo Biosynthesis of Vitamin C in Plants
J. Biol. Chem. 2003 278: 47483-47490. First Published on September 3, 2003; doi:10.1074/jbc.M309135200 [Abstract] [Full Text] [PDF]  

Ulrike Kirchner, Adrie H. Westphal, Rudolf Müller, and Willem J. H. van Berkel
Phenol Hydroxylase from Bacillus thermoglucosidasius A7, a Two-protein Component Monooxygenase with a Dual Role for FAD
J. Biol. Chem. 2003 278: 47545-47553. First Published on September 10, 2003; doi:10.1074/jbc.M307397200 [Abstract] [Full Text] [PDF]  

François-Xavier Wilhelm, Marcelle Wilhelm, and Abram Gabriel
Extension and Cleavage of the Polypurine Tract Plus-strand Primer by Ty1 Reverse Transcriptase
J. Biol. Chem. 2003 278: 47678-47684. First Published on September 18, 2003; doi:10.1074/jbc.M305162200 [Abstract] [Full Text] [PDF]  

Liisa Kukkola, Reija Hieta, Kari I. Kivirikko, and Johanna Myllyharju
Identification and Characterization of a Third Human, Rat, and Mouse Collagen Prolyl 4-Hydroxylase Isoenzyme
J. Biol. Chem. 2003 278: 47685-47693. First Published on September 18, 2003; doi:10.1074/jbc.M306806200 [Abstract] [Full Text] [PDF]  

Boris Illarionov, Ilka Haase, Adelbert Bacher, Markus Fischer, and Nicholas Schramek
Presteady State Kinetic Analysis of Riboflavin Synthase
J. Biol. Chem. 2003 278: 47700-47706. First Published on September 22, 2003; doi:10.1074/jbc.M305050200 [Abstract] [Full Text] [PDF]  

Noriko Yokoyama and W. Todd Miller
Biochemical Properties of the Cdc42-associated Tyrosine Kinase ACK1: SUBSTRATE SPECIFICITY, AUTOPHOSPHORYLATION, AND INTERACTION WITH Hck
J. Biol. Chem. 2003 278: 47713-47723. First Published on September 22, 2003; doi:10.1074/jbc.M306716200 [Abstract] [Full Text] [PDF]  

Christian D. P. Klein, Rolf Schiffmann, Gerd Folkers, Stefano Piana, and Ursula Röthlisberger
Protonation States of Methionine Aminopeptidase and Their Relevance for Inhibitor Binding and Catalytic Activity
J. Biol. Chem. 2003 278: 47862-47867. First Published on September 26, 2003; doi:10.1074/jbc.M305325200 [Abstract] [Full Text] [PDF] Supplemental Data  

Shin Numao, Douglas A. Kuntz, Stephen G. Withers, and David R. Rose
Insights into the Mechanism of Drosophila melanogaster Golgi {alpha}-Mannosidase II through the Structural Analysis of Covalent Reaction Intermediates
J. Biol. Chem. 2003 278: 48074-48083. First Published on September 5, 2003; doi:10.1074/jbc.M309249200 [Abstract] [Full Text] [PDF]  

Denis E. Kainov, Markus Pirttimaa, Roman Tuma, Sarah J. Butcher, George J. Thomas, Jr., Dennis H. Bamford, and Eugene V. Makeyev
RNA Packaging Device of Double-stranded RNA Bacteriophages, Possibly as Simple as Hexamer of P4 Protein
J. Biol. Chem. 2003 278: 48084-48091. First Published on September 8, 2003; doi:10.1074/jbc.M306928200 [Abstract] [Full Text] [PDF]  

Thomas H. Yun, Frank A. Baglia, Timothy Myles, Duraiswamy Navaneetham, José A. López, Peter N. Walsh, and Lawrence L. K. Leung
Thrombin Activation of Factor XI on Activated Platelets Requires the Interaction of Factor XI and Platelet Glycoprotein Ib{alpha} with Thrombin Anion-binding Exosites I and II, Respectively
J. Biol. Chem. 2003 278: 48112-48119. First Published on September 10, 2003; doi:10.1074/jbc.M306925200 [Abstract] [Full Text] [PDF]  

Anthony N. Hodder, Damien R. Drew, V. Chandana Epa, Mauro Delorenzi, Richard Bourgon, Susanne K. Miller, Robert L. Moritz, David F. Frecklington, Richard J. Simpson, Terence P. Speed, Robert N. Pike, and Brendan S. Crabb
Enzymic, Phylogenetic, and Structural Characterization of the Unusual Papain-like Protease Domain of Plasmodium falciparum SERA5
J. Biol. Chem. 2003 278: 48169-48177. First Published on September 17, 2003; doi:10.1074/jbc.M306755200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Fanis Missirlis, Jianguo Hu, Kim Kirby, Arthur J. Hilliker, Tracey A. Rouault, and John P. Phillips
Compartment-specific Protection of Iron-Sulfur Proteins by Superoxide Dismutase
J. Biol. Chem. 2003 278: 47365-47369. First Published on September 12, 2003; doi:10.1074/jbc.M307700200 [Abstract] [Full Text] [PDF]  

Stefan Kölker, Marina Schwab, Friederike Hörster, Sven Sauer, Angela Hinz, Nicole I. Wolf, Ertan Mayatepek, Georg F. Hoffmann, Jan A. M. Smeitink, and Jürgen G. Okun
Methylmalonic Acid, a Biochemical Hallmark of Methylmalonic Acidurias but No Inhibitor of Mitochondrial Respiratory Chain
J. Biol. Chem. 2003 278: 47388-47393. First Published on September 12, 2003; doi:10.1074/jbc.M308861200 [Abstract] [Full Text] [PDF]  

Dirk Flemming, Angela Schlitt, Volker Spehr, Tobias Bischof, and Thorsten Friedrich
Iron-Sulfur Cluster N2 of the Escherichia coli NADH:Ubiquinone Oxidoreductase (Complex I) Is Located on Subunit NuoB
J. Biol. Chem. 2003 278: 47602-47609. First Published on September 15, 2003; doi:10.1074/jbc.M308967200 [Abstract] [Full Text] [PDF]  

Jing Guo and Bernard D. Lemire
The Ubiquinone-binding Site of the Saccharomyces cerevisiae Succinate-Ubiquinone Oxidoreductase Is a Source of Superoxide
J. Biol. Chem. 2003 278: 47629-47635. First Published on September 16, 2003; doi:10.1074/jbc.M306312200 [Abstract] [Full Text] [PDF]  

Chomin Cunchillos and Guillaume Lecointre
Evolution of Amino Acid Metabolism Inferred through Cladistic Analysis
J. Biol. Chem. 2003 278: 47960-47970. First Published on August 29, 2003; doi:10.1074/jbc.M213028200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Takashi Sato, Masanori Gotoh, Katsue Kiyohara, Akihiko Kameyama, Tomomi Kubota, Norihiro Kikuchi, Yasuko Ishizuka, Hiroko Iwasaki, Akira Togayachi, Takashi Kudo, Takashi Ohkura, Hiroshi Nakanishi, and Hisashi Narimatsu
Molecular Cloning and Characterization of a Novel Human {beta}1,4-N-Acetylgalactosaminyltransferase, {beta}4GalNAc-T3, Responsible for the Synthesis of N,N'-Diacetyllactosediamine, GalNAc{beta}1–4GlcNAc
J. Biol. Chem. 2003 278: 47534-47544. First Published on September 9, 2003; doi:10.1074/jbc.M308857200 [Abstract] [Full Text] [PDF]  

Ulf Sommer, Hong Liu, and Tamara L. Doering
An {alpha}-1,3-Mannosyltransferase of Cryptococcus neoformans
J. Biol. Chem. 2003 278: 47724-47730. First Published on September 21, 2003; doi:10.1074/jbc.M307223200 [Abstract] [Full Text] [PDF]  

Marie-Jeanne Clément, Anne Imberty, Armelle Phalipon, Serge Pérez, Catherine Simenel, Laurence A. Mulard, and Muriel Delepierre
Conformational Studies of the O-specific Polysaccharide of Shigella flexneri 5a and of Four Related Synthetic Pentasaccharide Fragments Using NMR and Molecular Modeling
J. Biol. Chem. 2003 278: 47928-47936. First Published on August 18, 2003; doi:10.1074/jbc.M308259200 [Abstract] [Full Text] [PDF] Supplemental Data  

Pascal Gagneux, Monica Cheriyan, Nancy Hurtado-Ziola, Els C. M. Brinkman van der Linden, Dan Anderson, Harold McClure, Ajit Varki, and Nissi M. Varki
Human-specific Regulation of {alpha}2–6-linked Sialic Acids
J. Biol. Chem. 2003 278: 48245-48250. First Published on September 18, 2003; doi:10.1074/jbc.M309813200 [Abstract] [Full Text] [PDF] Supplemental Data  

Lipids and Lipoproteins:

Andreas Billich, Frederic Bornancin, Piroska Dévay, Diana Mechtcheriakova, Nicole Urtz, and Thomas Baumruker
Phosphorylation of the Immunomodulatory Drug FTY720 by Sphingosine Kinases
J. Biol. Chem. 2003 278: 47408-47415. First Published on September 16, 2003; doi:10.1074/jbc.M307687200 [Abstract] [Full Text] [PDF]  

Joyce Rauch, Jenny Gumperz, Cheryl Robinson, Markus Sköld, Chris Roy, David C. Young, Michel Lafleur, D. Branch Moody, Michael B. Brenner, Catherine E. Costello, and Samuel M. Behar
Structural Features of the Acyl Chain Determine Self-phospholipid Antigen Recognition by a CD1d-restricted Invariant NKT (iNKT) Cell
J. Biol. Chem. 2003 278: 47508-47515. First Published on September 8, 2003; doi:10.1074/jbc.M308089200 [Abstract] [Full Text] [PDF]  

Gunther Marsche, Robert Zimmermann, Seikoh Horiuchi, Narendra N. Tandon, Wolfgang Sattler, and Ernst Malle
Class B Scavenger Receptors CD36 and SR-BI Are Receptors for Hypochlorite-modified Low Density Lipoprotein
J. Biol. Chem. 2003 278: 47562-47570. First Published on September 10, 2003; doi:10.1074/jbc.M308428200 [Abstract] [Full Text] [PDF]  

Ryan E. Temel, Abraham K. Gebre, John S. Parks, and Lawrence L. Rudel
Compared with Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) 1 and Lecithin:Cholesterol Acyltransferase, ACAT2 Displays the Greatest Capacity to Differentiate Cholesterol from Sitosterol
J. Biol. Chem. 2003 278: 47594-47601. First Published on September 15, 2003; doi:10.1074/jbc.M308235200 [Abstract] [Full Text] [PDF]  

Anne E. Jenkins-Kruchten, Assumpta Bennaars-Eiden, James R. Ross, Wen-Jun Shen, Fredric B. Kraemer, and David A. Bernlohr
Fatty Acid-binding Protein-Hormone-sensitive Lipase Interaction: FATTY ACID DEPENDENCE ON BINDING
J. Biol. Chem. 2003 278: 47636-47643. First Published on September 16, 2003; doi:10.1074/jbc.M307680200 [Abstract] [Full Text] [PDF]  

Yoshio Yamauchi, Michi Hayashi, Sumiko Abe-Dohmae, and Shinji Yokoyama
Apolipoprotein A-I Activates Protein Kinase C{alpha} Signaling to Phosphorylate and Stabilize ATP Binding Cassette Transporter A1 for the High Density Lipoprotein Assembly
J. Biol. Chem. 2003 278: 47890-47897. First Published on September 2, 2003; doi:10.1074/jbc.M306258200 [Abstract] [Full Text] [PDF]  

Viktoria Gusarova, Jeffrey L. Brodsky, and Edward A. Fisher
Apolipoprotein B100 Exit from the Endoplasmic Reticulum (ER) Is COPII-dependent, and Its Lipidation to Very Low Density Lipoprotein Occurs Post-ER
J. Biol. Chem. 2003 278: 48051-48058. First Published on September 5, 2003; doi:10.1074/jbc.M306898200 [Abstract] [Full Text] [PDF]  

Gregory A. Graf, Liqing Yu, Wei-Ping Li, Robert Gerard, Pamela L. Tuma, Jonathan C. Cohen, and Helen H. Hobbs
ABCG5 and ABCG8 Are Obligate Heterodimers for Protein Trafficking and Biliary Cholesterol Excretion
J. Biol. Chem. 2003 278: 48275-48282. First Published on September 22, 2003; doi:10.1074/jbc.M310223200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Tadayuki Uetani, Tatsuaki Matsubara, Hideki Nomura, Toyoaki Murohara, and Shinsuke Nakayama
Ca2+-dependent Modulation of Intracellular Mg2+ Concentration with Amiloride and KB-R7943 in Pig Carotid Artery
J. Biol. Chem. 2003 278: 47491-47497. First Published on September 4, 2003; doi:10.1074/jbc.M307898200 [Abstract] [Full Text] [PDF]  

Qin Li, Xiang Luo, Weizhong Zeng, and Shmuel Muallem
Cell-specific Behavior of P2X7 Receptors in Mouse Parotid Acinar and Duct Cells
J. Biol. Chem. 2003 278: 47554-47561. First Published on September 10, 2003; doi:10.1074/jbc.M308306200 [Abstract] [Full Text] [PDF]  

Henri Wintz, Tama Fox, Ying-Ying Wu, Victoria Feng, Wenqiong Chen, Hur-Song Chang, Tong Zhu, and Chris Vulpe
Expression Profiles of Arabidopsis thaliana in Mineral Deficiencies Reveal Novel Transporters Involved in Metal Homeostasis
J. Biol. Chem. 2003 278: 47644-47653. First Published on September 16, 2003; doi:10.1074/jbc.M309338200 [Abstract] [Full Text] [PDF] Supplemental Data  

Klaus Brandenburg, Patrick Garidel, Jörg Andrä, Gudrun Jürgens, Mareike Müller, Alfred Blume, Michel H. J. Koch, and Jack Levin
Cross-linked Hemoglobin Converts Endotoxically Inactive Pentaacyl Endotoxins into a Physiologically Active Conformation
J. Biol. Chem. 2003 278: 47660-47669. First Published on September 17, 2003; doi:10.1074/jbc.M304743200 [Abstract] [Full Text] [PDF]  

Cristina Amat di San Filippo, Yuhuan Wang, and Nicola Longo
Functional Domains in the Carnitine Transporter OCTN2, Defective in Primary Carnitine Deficiency
J. Biol. Chem. 2003 278: 47776-47784. First Published on September 23, 2003; doi:10.1074/jbc.M307911200 [Abstract] [Full Text] [PDF]  

Leonard Dode, Jens Peter Andersen, Natalie Leslie, Jittima Dhitavat, Bente Vilsen, and Alain Hovnanian
Dissection of the Functional Differences between Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA) 1 and 2 Isoforms and Characterization of Darier Disease (SERCA2) Mutants by Steady-state and Transient Kinetic Analyses
J. Biol. Chem. 2003 278: 47877-47889. First Published on September 15, 2003; doi:10.1074/jbc.M306784200 [Abstract] [Full Text] [PDF] Supplemental Data  

Gabriel M. Belfort and Konstantin V. Kandror
Cellugyrin and Synaptogyrin Facilitate Targeting of Synaptophysin to a Ubiquitous Synaptic Vesicle-sized Compartment in PC12 Cells
J. Biol. Chem. 2003 278: 47971-47978. First Published on August 18, 2003; doi:10.1074/jbc.M304174200 [Abstract] [Full Text] [PDF]  

Wei Zheng, Wenrui Xie, Jianhua Zhang, Judith A. Strong, Ling Wang, Lei Yu, Ming Xu, and Luo Lu
Function of {gamma}-Aminobutyric Acid Receptor/Channel {rho}1 Subunits In Spinal Cord
J. Biol. Chem. 2003 278: 48321-48329. First Published on September 11, 2003; doi:10.1074/jbc.M307930200 [Abstract] [Full Text] [PDF]  

Carine Bonnon, Laurence Goutebroze, Natasha Denisenko-Nehrbass, Jean-Antoine Girault, and Catherine Faivre-Sarrailh
The Paranodal Complex of F3/Contactin and Caspr/Paranodin Traffics to the Cell Surface via a Non-conventional Pathway
J. Biol. Chem. 2003 278: 48339-48347. First Published on September 12, 2003; doi:10.1074/jbc.M309120200 [Abstract] [Full Text] [PDF]  

Zhenhui Chen, David L. Stokes, William J. Rice, and Larry R. Jones
Spatial and Dynamic Interactions between Phospholamban and the Canine Cardiac Ca2+ Pump Revealed with Use of Heterobifunctional Cross-linking Agents
J. Biol. Chem. 2003 278: 48348-48356. First Published on September 12, 2003; doi:10.1074/jbc.M309545200 [Abstract] [Full Text] [PDF]  

N. Luisa Hiller, Thomas Akompong, Jon S. Morrow, Anthony A. Holder, and Kasturi Haldar
Identification of a Stomatin Orthologue in Vacuoles Induced in Human Erythrocytes by Malaria Parasites: A ROLE FOR MICROBIAL RAFT PROTEINS IN APICOMPLEXAN VACUOLE BIOGENESIS
J. Biol. Chem. 2003 278: 48413-48421. First Published on September 10, 2003; doi:10.1074/jbc.M307266200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Claudia Miele, Audrey Riboulet, Maria Alessandra Maitan, Francesco Oriente, Chiara Romano, Pietro Formisano, Jean Giudicelli, Francesco Beguinot, and Emmanuel Van Obberghen
Human Glycated Albumin Affects Glucose Metabolism in L6 Skeletal Muscle Cells by Impairing Insulin-induced Insulin Receptor Substrate (IRS) Signaling through a Protein Kinase C{alpha}-mediated Mechanism
J. Biol. Chem. 2003 278: 47376-47387. First Published on September 11, 2003; doi:10.1074/jbc.M301088200 [Abstract] [Full Text] [PDF]  

Gress Kadaré, Madeleine Toutant, Etienne Formstecher, Jean-Christophe Corvol, Michèle Carnaud, Marie-Claude Boutterin, and Jean-Antoine Girault
PIAS1-mediated Sumoylation of Focal Adhesion Kinase Activates Its Autophosphorylationn
J. Biol. Chem. 2003 278: 47434-47440. First Published on September 18, 2003; doi:10.1074/jbc.M308562200 [Abstract] [Full Text] [PDF]  

Gail Ferguson, Isabelle Mothe-Satney, and John C. Lawrence, Jr.
Ser-64 and Ser-111 in PHAS-I Are Dispensable for Insulin-stimulated Dissociation from eIF4E
J. Biol. Chem. 2003 278: 47459-47465. First Published on September 24, 2003; doi:10.1074/jbc.M307949200 [Abstract] [Full Text] [PDF]  

Beth Noble, Lorena A. Kallal, Mark H. Pausch, and Jeffrey L. Benovic
Development of a Yeast Bioassay to Characterize G Protein-coupled Receptor Kinases: IDENTIFICATION OF AN NH2-TERMINAL REGION ESSENTIAL FOR RECEPTOR PHOSPHORYLATION
J. Biol. Chem. 2003 278: 47466-47476. First Published on September 24, 2003; doi:10.1074/jbc.M308257200 [Abstract] [Full Text] [PDF]  

Makio Mogi and Akifumi Togari
Activation of Caspases Is Required for Osteoblastic Differentiation
J. Biol. Chem. 2003 278: 47477-47482. First Published on September 3, 2003; doi:10.1074/jbc.M307055200 [Abstract] [Full Text] [PDF]  

Susanne Grether-Beck, Ingo Felsner, Heidi Brenden, and Jean Krutmann
Mitochondrial Cytochrome c Release Mediates Ceramide-induced Activator Protein 2 Activation and Gene Expression in Keratinocytes
J. Biol. Chem. 2003 278: 47498-47507. First Published on September 2, 2003; doi:10.1074/jbc.M309511200 [Abstract] [Full Text] [PDF]  

Shigeyuki Nada, Takaki Shima, Hiroyuki Yanai, Holger Husi, Seth G. N. Grant, Masato Okada, and Tetsu Akiyama
Identification of PSD-93 as a Substrate for the Src Family Tyrosine Kinase Fyn
J. Biol. Chem. 2003 278: 47610-47621. First Published on September 16, 2003; doi:10.1074/jbc.M303873200 [Abstract] [Full Text] [PDF]  

Young-Kwon Kim, Song-Jung Kim, Atsuko Yatani, Yanhong Huang, Germana Castelli, Dorothy E. Vatner, Jing Liu, Qizhi Zhang, Gissela Diaz, Renata Zieba, Jill Thaisz, Alessandra Drusco, Carlo Croce, Junichi Sadoshima, Gianluigi Condorelli, and Stephen F. Vatner
Mechanism of Enhanced Cardiac Function in Mice with Hypertrophy Induced by Overexpressed Akt
J. Biol. Chem. 2003 278: 47622-47628. First Published on September 16, 2003; doi:10.1074/jbc.M305909200 [Abstract] [Full Text] [PDF]  

Ahmad Zahabi, Sylvie Picard, Nadia Fortin, Timothy L. Reudelhuber, and Christian F. Deschepper
Expression of Constitutively Active Guanylate Cyclase in Cardiomyocytes Inhibits the Hypertrophic Effects of Isoproterenol and Aortic Constriction on Mouse Hearts
J. Biol. Chem. 2003 278: 47694-47699. First Published on September 18, 2003; doi:10.1074/jbc.M309661200 [Abstract] [Full Text] [PDF]  

Masatoshi Abe, Chin-Han Ho, Kristine E. Kamm, and Frederick Grinnell
Different Molecular Motors Mediate Platelet-derived Growth Factor and Lysophosphatidic Acid-stimulated Floating Collagen Matrix Contraction
J. Biol. Chem. 2003 278: 47707-47712. First Published on September 21, 2003; doi:10.1074/jbc.M306228200 [Abstract] [Full Text] [PDF]  

Qin Wang, Gordon R. Pfeiffer, II, and William A. Gaarde
Activation of SRC Tyrosine Kinases in Response to ICAM-1 Ligation in Pulmonary Microvascular Endothelial Cells
J. Biol. Chem. 2003 278: 47731-47743. First Published on September 22, 2003; doi:10.1074/jbc.M308466200 [Abstract] [Full Text] [PDF]  

Maria Adelaida García-Gimeno, Iván Muñoz, Joaquín Ariño, and Pascual Sanz
Molecular Characterization of Ypi1, a Novel Saccharomyces cerevisiae Type 1 Protein Phosphatase Inhibitor
J. Biol. Chem. 2003 278: 47744-47752. First Published on September 23, 2003; doi:10.1074/jbc.M306157200 [Abstract] [Full Text] [PDF]  

Xiaoyan Han, Pamela J. Boyd, Stephen Colgan, Joseph A. Madri, and Tara L. Haas
Transcriptional Up-regulation of Endothelial Cell Matrix Metalloproteinase-2 in Response to Extracellular Cues Involves GATA-2
J. Biol. Chem. 2003 278: 47785-47791. First Published on September 25, 2003; doi:10.1074/jbc.M309482200 [Abstract] [Full Text] [PDF]  

Rachel G. Khadaroo, Andras Kapus, Kinga A. Powers, Myron I. Cybulsky, John C. Marshall, and Ori D. Rotstein
Oxidative Stress Reprograms Lipopolysaccharide Signaling via Src Kinase-dependent Pathway in RAW 264.7 Macrophage Cell Line
J. Biol. Chem. 2003 278: 47834-47841. First Published on August 1, 2003; doi:10.1074/jbc.M302660200 [Abstract] [Full Text] [PDF]  

Alexander Dietrich, Michael Mederos y Schnitzler, Jens Emmel, Hermann Kalwa, Thomas Hofmann, and Thomas Gudermann
N-Linked Protein Glycosylation Is a Major Determinant for Basal TRPC3 and TRPC6 Channel Activity
J. Biol. Chem. 2003 278: 47842-47852. First Published on September 11, 2003; doi:10.1074/jbc.M302983200 [Abstract] [Full Text] [PDF]  

Johann Sohn, HyeSook Youn, MyoungKun Jeoung, YongBum Koo, ChongSeoung Yi, Inhae Ji, and Tae H. Ji
Orientation of Follicle-stimulating Hormone (FSH) Subunits Complexed with the FSH Receptor: {beta} SUBUNIT TOWARD THE N TERMINUS OF EXODOMAIN AND {alpha} SUBUNIT TO EXOLOOP 3
J. Biol. Chem. 2003 278: 47868-47876. First Published on September 8, 2003; doi:10.1074/jbc.M307751200 [Abstract] [Full Text] [PDF]  

Svend Kjær and Carlos F. Ibáñez
Identification of a Surface for Binding to the GDNF-GFR{alpha}1 Complex in the First Cadherin-like Domain of RET
J. Biol. Chem. 2003 278: 47898-47904. First Published on September 26, 2003; doi:10.1074/jbc.M309772200 [Abstract] [Full Text] [PDF] Supplemental Data  

Claudia Figueroa, Samantha Tarras, Jennifer Taylor, and Anne B. Vojtek
Akt2 Negatively Regulates Assembly of the POSH-MLK-JNK Signaling Complex
J. Biol. Chem. 2003 278: 47922-47927. First Published on September 21, 2003; doi:10.1074/jbc.M307357200 [Abstract] [Full Text] [PDF]  

Jeffrey J. Saucerman, Laurence L. Brunton, Anushka P. Michailova, and Andrew D. McCulloch
Modeling {beta}-Adrenergic Control of Cardiac Myocyte Contractility in Silico
J. Biol. Chem. 2003 278: 47997-48003. First Published on September 12, 2003; doi:10.1074/jbc.M308362200 [Abstract] [Full Text] [PDF] Supplemental Data  

Feng Jiang, Pengfei Li, Albert J. Fornace, Jr., Santo V. Nicosia, and Wenlong Bai
G2/M Arrest by 1,25-Dihydroxyvitamin D3 in Ovarian Cancer Cells Mediated through the Induction of GADD45 via an Exonic Enhancer
J. Biol. Chem. 2003 278: 48030-48040. First Published on September 23, 2003; doi:10.1074/jbc.M308430200 [Abstract] [Full Text] [PDF]  

María A. Balboa, Yasuhito Shirai, Guido Gaietta, Mark H. Ellisman, Jesús Balsinde, and Edward A. Dennis
Localization of Group V Phospholipase A2 in Caveolin-enriched Granules in Activated P388D1 Macrophage-like Cells
J. Biol. Chem. 2003 278: 48059-48065. First Published on September 8, 2003; doi:10.1074/jbc.M305904200 [Abstract] [Full Text] [PDF]  

Tong-Shin Chang, Myung Jin Kim, Kanghyun Ryoo, Jihyun Park, Soo-Jung Eom, Jaekyung Shim, Keiichi I. Nakayama, Keiko Nakayama, Motowo Tomita, Katsuhiko Takahashi, Min-Jae Lee, and Eui-Ju Choi
p57KIP2 Modulates Stress-activated Signaling by Inhibiting c-Jun NH2-terminal Kinase/Stress-activated Protein Kinase
J. Biol. Chem. 2003 278: 48092-48098. First Published on September 8, 2003; doi:10.1074/jbc.M309421200 [Abstract] [Full Text] [PDF]  

Blanca Llompart, Enric Castells, Adolfo Río, Ramon Roca, Alejandro Ferrando, Virginia Stiefel, Pere Puigdomènech, and Josep M. Casacuberta
The Direct Activation of MIK, a Germinal Center Kinase (GCK)-like Kinase, by MARK, a Maize Atypical Receptor Kinase, Suggests a New Mechanism for Signaling through Kinase-dead Receptors
J. Biol. Chem. 2003 278: 48105-48111. First Published on September 9, 2003; doi:10.1074/jbc.M307482200 [Abstract] [Full Text] [PDF]  

Salimuddin Shah, Andreas Hecht, Richard Pestell, and Stephen W. Byers
Trans-repression of {beta}-Catenin Activity by Nuclear Receptors
J. Biol. Chem. 2003 278: 48137-48145. First Published on September 12, 2003; doi:10.1074/jbc.M307154200 [Abstract] [Full Text] [PDF]  

Valentin G. Robu, Emily S. Pfeiffer, Seth L. Robia, Ravi C. Balijepalli, YeQing Pi, Timothy J. Kamp, and Jeffery W. Walker
Localization of Functional Endothelin Receptor Signaling Complexes in Cardiac Transverse Tubules
J. Biol. Chem. 2003 278: 48154-48161. First Published on September 12, 2003; doi:10.1074/jbc.M304396200 [Abstract] [Full Text] [PDF]  

David C. Willhite, Timothy L. Cover, and Steven R. Blanke
Cellular Vacuolation and Mitochondrial Cytochrome c Release Are Independent Outcomes of Helicobacter pylori Vacuolating Cytotoxin Activity That Are Each Dependent on Membrane Channel Formation
J. Biol. Chem. 2003 278: 48204-48209. First Published on September 16, 2003; doi:10.1074/jbc.M304131200 [Abstract] [Full Text] [PDF]  

Knut Tomas Dalen, Stine Marie Ulven, Krister Bamberg, Jan-Åke Gustafsson, and Hilde I. Nebb
Expression of the Insulin-responsive Glucose Transporter GLUT4 in Adipocytes Is Dependent on Liver X Receptor {alpha}
J. Biol. Chem. 2003 278: 48283-48291. First Published on September 11, 2003; doi:10.1074/jbc.M302287200 [Abstract] [Full Text] [PDF]  

Young-Woo Seo, Jin Na Shin, Kang Hee Ko, Jong Hee Cha, Jae Yoon Park, Byoung Rai Lee, Cheol-Won Yun, Young Myeong Kim, Dai-wu Seol, Dong-wook Kim, Xiao-Ming Yin, and Tae-Hyoung Kim
The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death
J. Biol. Chem. 2003 278: 48292-48299. First Published on September 18, 2003; doi:10.1074/jbc.M308785200 [Abstract] [Full Text] [PDF]  

Alberto Visintin, Eicke Latz, Brian G. Monks, Terje Espevik, and Douglas T. Golenbock
Lysines 128 and 132 Enable Lipopolysaccharide Binding to MD-2, Leading to Toll-like Receptor-4 Aggregation and Signal Transduction
J. Biol. Chem. 2003 278: 48313-48320. First Published on September 5, 2003; doi:10.1074/jbc.M306802200 [Abstract] [Full Text] [PDF]  

Jinhong Huang, Tamae Asawa, Tsuyoshi Takato, and Ryuichi Sakai
Cooperative Roles of Fyn and Cortactin in Cell Migration of Metastatic Murine Melanoma
J. Biol. Chem. 2003 278: 48367-48376. First Published on September 16, 2003; doi:10.1074/jbc.M308213200 [Abstract] [Full Text] [PDF]  

Patrick Most, Melanie Boerries, Carmen Eicher, Christopher Schweda, Philipp Ehlermann, Sven T. Pleger, Eva Loeffler, Walter J. Koch, Hugo A. Katus, Cora-Ann Schoenenberger, and Andrew Remppis
Extracellular S100A1 Protein Inhibits Apoptosis in Ventricular Cardiomyocytes via Activation of the Extracellular Signal-regulated Protein Kinase 1/2 (ERK1/2)
J. Biol. Chem. 2003 278: 48404-48412. First Published on September 6, 2003; doi:10.1074/jbc.M308587200 [Abstract] [Full Text] [PDF]  

Ping Xu, Katsuji Yoshioka, Daisuke Yoshimura, Yohei Tominaga, Tomoko Nishioka, Michihiko Ito, and Yusaku Nakabeppu
In Vitro Development of Mouse Embryonic Stem Cells Lacking JNK/Stress-activated Protein Kinase-associated Protein 1 (JSAP1) Scaffold Protein Revealed Its Requirement during Early Embryonic Neurogenesis
J. Biol. Chem. 2003 278: 48422-48433. First Published on September 10, 2003; doi:10.1074/jbc.M307888200 [Abstract] [Full Text] [PDF]  

Kohjiro Ueki, David A. Fruman, Claudine M. Yballe, Mathias Fasshauer, Johannes Klein, Tomoichiro Asano, Lewis C. Cantley, and C. Ronald Kahn
Positive and Negative Roles of p85{alpha} and p85{beta} Regulatory Subunits of Phosphoinositide 3-Kinase in Insulin Signaling
J. Biol. Chem. 2003 278: 48453-48466. First Published on September 22, 2003; doi:10.1074/jbc.M305602200 [Abstract] [Full Text] [PDF]  

Christine Tkaczyk, Michael A. Beaven, Saskia M. Brachman, Dean D. Metcalfe, and Alasdair M. Gilfillan
The Phospholipase C{gamma}1-dependent Pathway of Fc{epsilon}RI-mediated Mast Cell Activation Is Regulated Independently of Phosphatidylinositol 3-Kinase
J. Biol. Chem. 2003 278: 48474-48484. First Published on September 16, 2003; doi:10.1074/jbc.M301350200 [Abstract] [Full Text] [PDF]  

Zheng Tu and Frank S. Lee
Subdomain VIII Is a Specificity-determining Region in MEKK1
J. Biol. Chem. 2003 278: 48498-48505. First Published on September 18, 2003; doi:10.1074/jbc.M304234200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Constance Zlot, Gladys Ingle, Joanne Hongo, Suya Yang, Zhong Sheng, Ralph Schwall, Nicholas Paoni, Fay Wang, Franklin V. Peale, Jr., and Mary E. Gerritsen
Stanniocalcin 1 Is an Autocrine Modulator of Endothelial Angiogenic Responses to Hepatocyte Growth Factor
J. Biol. Chem. 2003 278: 47654-47659. First Published on September 17, 2003; doi:10.1074/jbc.M301353200 [Abstract] [Full Text] [PDF]  

Gina Fusaro, Piyali Dasgupta, Shipra Rastogi, Bharat Joshi, and Srikumar Chellappan
Prohibitin Induces the Transcriptional Activity of p53 and Is Exported from the Nucleus upon Apoptotic Signaling
J. Biol. Chem. 2003 278: 47853-47861. First Published on September 18, 2003; doi:10.1074/jbc.M305171200 [Abstract] [Full Text] [PDF]  

Konstadinos Moissoglu and Irwin H. Gelman
v-Src Rescues Actin-based Cytoskeletal Architecture and Cell Motility and Induces Enhanced Anchorage Independence during Oncogenic Transformation of Focal Adhesion Kinase-null Fibroblasts
J. Biol. Chem. 2003 278: 47946-47959. First Published on September 18, 2003; doi:10.1074/jbc.M302720200 [Abstract] [Full Text] [PDF]  

Laura Leung, Mandy Kwong, Stephen Hou, Candy Lee, and Jefferson Y. Chan
Deficiency of the Nrf1 and Nrf2 Transcription Factors Results in Early Embryonic Lethality and Severe Oxidative Stress
J. Biol. Chem. 2003 278: 48021-48029. First Published on September 10, 2003; doi:10.1074/jbc.M308439200 [Abstract] [Full Text] [PDF]  

Michael T. Sturniolo, Shervin R. Dashti, Anne Deucher, Ellen A. Rorke, Ann-Marie Broome, Roshantha A. S. Chandraratna, Tiffany Keepers, and Richard L. Eckert
A Novel Tumor Suppressor Protein Promotes Keratinocyte Terminal Differentiation via Activation of Type I Transglutaminase
J. Biol. Chem. 2003 278: 48066-48073. First Published on August 19, 2003; doi:10.1074/jbc.M307215200 [Abstract] [Full Text] [PDF]  

J. Mohamad Fakruddin and Jeffrey Laurence
HIV Envelope gp120-mediated Regulation of Osteoclastogenesis via Receptor Activator of Nuclear Factor {kappa}B Ligand (RANKL) Secretion and Its Modulation by Certain HIV Protease Inhibitors through Interferon-{gamma}/RANKL Cross-talk
J. Biol. Chem. 2003 278: 48251-48258. First Published on September 15, 2003; doi:10.1074/jbc.M304676200 [Abstract] [Full Text] [PDF]  

Yu Koshizuka, Takashi Yamada, Kazuto Hoshi, Toru Ogasawara, Ung-il Chung, Hirotaka Kawano, Yusuke Nakamura, Kozo Nakamura, Shiro Ikegawa, and Hiroshi Kawaguchi
Cystatin 10, a Novel Chondrocyte-specific Protein, May Promote the Last Steps of the Chondrocyte Differentiation Pathway
J. Biol. Chem. 2003 278: 48259-48266. First Published on September 17, 2003; doi:10.1074/jbc.M211639200 [Abstract] [Full Text] [PDF]  

Karen L. Soldano, Arif Jivan, Christopher V. Nicchitta, and Daniel T. Gewirth
Structure of the N-terminal Domain of GRP94: BASIS FOR LIGAND SPECIFICITY AND REGULATION
J. Biol. Chem. 2003 278: 48330-48338. First Published on September 11, 2003; doi:10.1074/jbc.M308661200 [Abstract] [Full Text] [PDF]  

Karim Nayernia, Franz Vauti, Andreas Meinhardt, Christina Cadenas, Stephan Schweyer, Barbara I. Meyer, Iris Schwandt, Kamal Chowdhury, Wolfgang Engel, and Hans-Henning Arnold
Inactivation of a Testis-specific Lis1 Transcript in Mice Prevents Spermatid Differentiation and Causes Male Infertility
J. Biol. Chem. 2003 278: 48377-48385. First Published on September 16, 2003; doi:10.1074/jbc.M309583200 [Abstract] [Full Text] [PDF]  

Katherine A. Tucker, Fulvio Reggiori, William A. Dunn, Jr., and Daniel J. Klionsky
Atg23 Is Essential for the Cytoplasm to Vacuole Targeting Pathway and Efficient Autophagy but Not Pexophagy
J. Biol. Chem. 2003 278: 48445-48452. First Published on September 22, 2003; doi:10.1074/jbc.M309238200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Maria Hrmova, Tomoya Imai, Simon J. Rutten, Jon K. Fairweather, Ludovic Pelosi, Vincent Bulone, Hugues Driguez, and Geoffrey B. Fincher
Mutated barley (1,3)-{beta}-D-glucan endohydrolases synthesize crystalline (1,3)-{beta}-D-glucans. Vol. 277 (2002) 30102–30111
J. Biol. Chem. 2003 278: 48506. [Full Text] [PDF]  

Vladimir V. Kalinichenko, Galina A. Gusarova, Yongjun Tan, I-Ching Wang, Michael L. Major, Xinhe Wang, Helena M. Yoder, and Robert H. Costa
Ubiquitous expression of the forkhead box M1B transgene accelerates proliferation of distinct pulmonary cell types following lung injury. Vol. 278 (2003) 37888–37894
J. Biol. Chem. 2003 278: 48506. [Full Text] [PDF]  

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