JBC -- Table of Contents (Dec 12 2003, 278, (50))

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Franklin A. Hays, Jeffrey Watson, and P. Shing Ho: Caution! DNA Crossing: Crystal Structures of Holliday Junctions
J. Biol. Chem. 2003 278: -49666. First Published on October 16, 2003; doi:10.1074/jbc.R300033200 [Full Text] [PDF]

Accelerated Publications:

John A. Putkey, Quinn Kleerekoper, Tara R. Gaertner, and M. Neal Waxham: A New Role for IQ Motif Proteins in Regulating Calmodulin Function
J. Biol. Chem. 2003 278: -49670. First Published on October 9, 2003; doi:10.1074/jbc.C300372200 [Abstract] [Full Text] [PDF] Supplemental Data

Shigeo Sato, Chieri Tomomori-Sato, Charles A. S. Banks, Tari J. Parmely, Irina Sorokina, Christopher S. Brower, Ronald C. Conaway, and Joan Weliky Conaway: A Mammalian Homolog of Drosophila melanogaster Transcriptional Coactivator Intersex Is a Subunit of the Mammalian Mediator Complex
J. Biol. Chem. 2003 278: -49674. First Published on October 22, 2003; doi:10.1074/jbc.C300444200 [Abstract] [Full Text] [PDF] Supplemental Data

Vladimir L. Kolossov and Constantin A. Rebeiz: Chloroplast Biogenesis 88: PROTOCHLOROPHYLLIDE b OCCURS IN GREEN BUT NOT IN ETIOLATED PLANTS
J. Biol. Chem. 2003 278: -49678. First Published on October 31, 2003; doi:10.1074/jbc.C300449200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Hong Dou, Sankar Mitra, and Tapas K. Hazra: Repair of Oxidized Bases in DNA Bubble Structures by Human DNA Glycosylases NEIL1 and NEIL2
J. Biol. Chem. 2003 278: -49684. First Published on September 30, 2003; doi:10.1074/jbc.M308658200 [Abstract] [Full Text] [PDF]

Jingsong Yang, Michael A. Trakselis, Rosa Maria Roccasecca, and Stephen J. Benkovic: The Application of a Minicircle Substrate in the Study of the Coordinated T4 DNA Replication
J. Biol. Chem. 2003 278: -49838. First Published on September 18, 2003; doi:10.1074/jbc.M307406200 [Abstract] [Full Text] [PDF]

Michael A. Trakselis, Rosa Maria Roccasecca, Jingsong Yang, Ann M. Valentine, and Stephen J. Benkovic: Dissociative Properties of the Proteins within the Bacteriophage T4 Replisome
J. Biol. Chem. 2003 278: -49849. First Published on September 18, 2003; doi:10.1074/jbc.M307405200 [Abstract] [Full Text] [PDF]

Xiang Liu, Sujata Choudhury, and Rabindra Roy: In Vitro and in Vivo Dimerization of Human Endonuclease III Stimulates Its Activity
J. Biol. Chem. 2003 278: -50069. First Published on September 30, 2003; doi:10.1074/jbc.M309997200 [Abstract] [Full Text] [PDF]

Robert J. Kokoska, Scott D. McCulloch, and Thomas A. Kunkel: The Efficiency and Specificity of Apurinic/Apyrimidinic Site Bypass by Human DNA Polymerase ${eta}$ and Sulfolobus solfataricus Dpo4
J. Biol. Chem. 2003 278: -50545. First Published on September 30, 2003; doi:10.1074/jbc.M308515200 [Abstract] [Full Text] [PDF]

Dennis Gomez, Nassera Aouali, Arturo Londoño-Vallejo, Laurent Lacroix, Frédérique Mégnin-Chanet, Thibault Lemarteleur, Céline Douarre, Kazuo Shin-ya, Patrick Mailliet, Chantal Trentesaux, Hamid Morjani, Jean-Louis Mergny, and Jean-François Riou: Resistance to the Short Term Antiproliferative Activity of the G-quadruplex Ligand 12459 Is Associated with Telomerase Overexpression and Telomere Capping Alteration
J. Biol. Chem. 2003 278: -50562. First Published on October 2, 2003; doi:10.1074/jbc.M308440200 [Abstract] [Full Text] [PDF]

Nina Yao, Lee Coryell, Dan Zhang, Roxana E. Georgescu, Jeff Finkelstein, Maria M. Coman, Manju M. Hingorani, and Mike O'Donnell: Replication Factor C Clamp Loader Subunit Arrangement within the Circular Pentamer and Its Attachment Points to Proliferating Cell Nuclear Antigen
J. Biol. Chem. 2003 278: -50753. First Published on October 6, 2003; doi:10.1074/jbc.M309206200 [Abstract] [Full Text] [PDF]

Scott D. McCulloch, Liya Gu, and Guo-Min Li: Nick-dependent and -independent Processing of Large DNA Loops in Human Cells
J. Biol. Chem. 2003 278: -50809. First Published on September 30, 2003; doi:10.1074/jbc.M309025200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Yiqing Chi, Vitalyi Senyuk, Soumen Chakraborty, and Giuseppina Nucifora: EVI1 Promotes Cell Proliferation by Interacting with BRG1 and Blocking the Repression of BRG1 on E2F1 Activity
J. Biol. Chem. 2003 278: -49811. First Published on October 10, 2003; doi:10.1074/jbc.M309645200 [Abstract] [Full Text] [PDF]

Yubin Ge, Tanya L. Jensen, Larry H. Matherly, and Jeffrey W. Taub: Physical and Functional Interactions between USF and Sp1 Proteins Regulate Human Deoxycytidine Kinase Promoter Activity
J. Biol. Chem. 2003 278: -49910. First Published on September 26, 2003; doi:10.1074/jbc.M305085200 [Abstract] [Full Text] [PDF]

Glen L. Wheeler, Eleanor W. Trotter, Ian W. Dawes, and Chris M. Grant: Coupling of the Transcriptional Regulation of Glutathione Biosynthesis to the Availability of Glutathione and Methionine via the Met4 and Yap1 Transcription Factors
J. Biol. Chem. 2003 278: -49928. First Published on September 26, 2003; doi:10.1074/jbc.M310156200 [Abstract] [Full Text] [PDF]

Dawn A. Bradbury, Robert Newton, Yong M. Zhu, Hala El-Haroun, Lisa Corbett, and Alan J Knox: Cyclooxygenase-2 Induction by Bradykinin in Human Pulmonary Artery Smooth Muscle Cells Is Mediated by the Cyclic AMP Response Element through a Novel Autocrine Loop Involving Endogenous Prostaglandin E₂, E-prostanoid 2 (EP2), and EP4 Receptors
J. Biol. Chem. 2003 278: -49964. First Published on September 29, 2003; doi:10.1074/jbc.M307964200 [Abstract] [Full Text] [PDF]

James Fernandez, Alex B. Lopez, Chuanping Wang, Rangnath Mishra, Lingyin Zhou, Ibrahim Yaman, Martin D. Snider, and Maria Hatzolgou: Transcriptional Control of the Arginine/Lysine Transporter, Cat-1, by Physiological Stress
J. Biol. Chem. 2003 278: -50009. First Published on September 30, 2003; doi:10.1074/jbc.M305903200 [Abstract] [Full Text] [PDF]

Dong-Ju Shin, Jose A. Campos, Gregorio Gil, and Timothy F. Osborne: PGC-1 ${alpha}$ Activates CYP7A1 and Bile Acid Biosynthesis
J. Biol. Chem. 2003 278: -50052. First Published on September 30, 2003; doi:10.1074/jbc.M309736200 [Abstract] [Full Text] [PDF]

Chunfen Zhang, Honggao Yan, and Zachary F. Burton: Combinatorial Control of Human RNA Polymerase II (RNAP II) Pausing and Transcript Cleavage by Transcription Factor IIF, Hepatitis ${delta}$ Antigen, and Stimulatory Factor II
J. Biol. Chem. 2003 278: -50111. First Published on September 23, 2003; doi:10.1074/jbc.M307590200 [Abstract] [Full Text] [PDF]

Jodi Dufner-Beattie, S. Joshua Langmade, Fudi Wang, David Eide, and Glen K. Andrews: Structure, Function, and Regulation of a Subfamily of Mouse Zinc Transporter Genes
J. Biol. Chem. 2003 278: -50150. First Published on October 2, 2003; doi:10.1074/jbc.M304163200 [Abstract] [Full Text] [PDF]

Judith K. Davie, Diane G. Edmondson, Cherie B. Coco, and Sharon Y. R. Dent: Tup1-Ssn6 Interacts with Multiple Class I Histone Deacetylases in Vivo
J. Biol. Chem. 2003 278: -50162. First Published on October 2, 2003; doi:10.1074/jbc.M309753200 [Abstract] [Full Text] [PDF]

Amanda M. de Mestre, Levon M. Khachigian, Fernando S. Santiago, Maria A. Staykova, and Mark D. Hulett: Regulation of Inducible Heparanase Gene Transcription in Activated T Cells by Early Growth Response 1
J. Biol. Chem. 2003 278: -50385. First Published on September 30, 2003; doi:10.1074/jbc.M310154200 [Abstract] [Full Text] [PDF]

Gethin Thomas, Pierre Moffatt, Patrick Salois, Marie-Hélène Gaumond, Rock Gingras, Éric Godin, Dengshun Miao, David Goltzman, and Christian Lanctôt: Osteocrin, a Novel Bone-specific Secreted Protein That Modulates the Osteoblast Phenotype
J. Biol. Chem. 2003 278: -50571. First Published on October 1, 2003; doi:10.1074/jbc.M307310200 [Abstract] [Full Text] [PDF]

Chakib Mouslim, Tammy Latifi, and Eduardo A. Groisman: Signal-dependent Requirement for the Co-activator Protein RcsA in Transcription of the RcsB-regulated ugd Gene
J. Biol. Chem. 2003 278: -50595. First Published on September 26, 2003; doi:10.1074/jbc.M309433200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Walt F. Lima, Hongjiang Wu, Josh G. Nichols, Thazha P. Prakash, Vasulinga Ravikumar, and Stanley T. Crooke: Human RNase H1 Uses One Tryptophan and Two Lysines to Position the Enzyme at the 3'-DNA/5'-RNA Terminus of the Heteroduplex Substrate
J. Biol. Chem. 2003 278: -49867. First Published on September 23, 2003; doi:10.1074/jbc.M306543200 [Abstract] [Full Text] [PDF]

Jonathan Villemaire, Isabelle Dion, Sherif Abou Elela, and Benoit Chabot: Reprogramming Alternative Pre-messenger RNA Splicing through the Use of Protein-binding Antisense Oligonucleotides
J. Biol. Chem. 2003 278: -50039. First Published on September 30, 2003; doi:10.1074/jbc.M308897200 [Abstract] [Full Text] [PDF]

Yusuke Miyanari, Makoto Hijikata, Masashi Yamaji, Masahiro Hosaka, Hitoshi Takahashi, and Kunitada Shimotohno: Hepatitis C Virus Non-structural Proteins in the Probable Membranous Compartment Function in Viral Genome Replication
J. Biol. Chem. 2003 278: -50308. First Published on September 8, 2003; doi:10.1074/jbc.M305684200 [Abstract] [Full Text] [PDF]

Oliver A. Kent, Ayube Reayi, Louise Foong, Kaari A. Chilibeck, and Andrew M. MacMillan: Structuring of the 3' Splice Site by U2AF65
J. Biol. Chem. 2003 278: -50577. First Published on September 23, 2003; doi:10.1074/jbc.M307976200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Amareth Lim, Shantanu Sengupta, Mark E. McComb, Roger Théberge, William G. Wilson, Catherine E. Costello, and Donald W. Jacobsen: In Vitro and in Vivo Interactions of Homocysteine with Human Plasma Transthyretin
J. Biol. Chem. 2003 278: -49713. First Published on September 24, 2003; doi:10.1074/jbc.M306748200 [Abstract] [Full Text] [PDF]

Linda Doerwald, Carla Onnekink, Siebe T. van Genesen, Wilfried W. de Jong, and Nicolette H. Lubsen: Translational Thermotolerance Provided by Small Heat Shock Proteins Is Limited to Cap-dependent Initiation and Inhibited by 2-Aminopurine
J. Biol. Chem. 2003 278: -49750. First Published on September 30, 2003; doi:10.1074/jbc.M302914200 [Abstract] [Full Text] [PDF]

Anne-Catherine Schlaeppi, Tatiana Malherbe, and Peter Bütikofer: Coordinate Expression of GPEET Procyclin and Its Membrane-associated Kinase in Trypanosoma brucei Procyclic Forms
J. Biol. Chem. 2003 278: -49987. First Published on September 29, 2003; doi:10.1074/jbc.M309548200 [Abstract] [Full Text] [PDF]

Tomoko Yamada-Inagawa, Takashi Okuno, Kiyonobu Karata, Kunitoshi Yamanaka, and Teru Ogura: Conserved Pore Residues in the AAA Protease FtsH Are Important for Proteolysis and Its Coupling to ATP Hydrolysis
J. Biol. Chem. 2003 278: -50187. First Published on September 26, 2003; doi:10.1074/jbc.M308327200 [Abstract] [Full Text] [PDF]

Elina Nikko, Anne-Marie Marini, and Bruno André: Permease Recycling and Ubiquitination Status Reveal a Particular Role for Bro1 in the Multivesicular Body Pathway
J. Biol. Chem. 2003 278: -50743. First Published on September 30, 2003; doi:10.1074/jbc.M306953200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Gary Guishan Xiao, Meiying Wang, Ning Li, Joseph A. Loo, and Andre E. Nel: Use of Proteomics to Demonstrate a Hierarchical Oxidative Stress Response to Diesel Exhaust Particle Chemicals in a Macrophage Cell Line
J. Biol. Chem. 2003 278: -50790. First Published on September 30, 2003; doi:10.1074/jbc.M306423200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Daphné Georlette, Vinciane Blaise, Christophe Dohmen, Fabrice Bouillenne, Benjamin Damien, Eric Depiereux, Charles Gerday, Vladimir N. Uversky, and Georges Feller: Cofactor Binding Modulates the Conformational Stabilities and Unfolding Patterns of NAD⁺-dependent DNA Ligases from Escherichia coli and Thermus scotoductus
J. Biol. Chem. 2003 278: -49953. First Published on September 30, 2003; doi:10.1074/jbc.M307761200 [Abstract] [Full Text] [PDF]

Juan A. Osés-Prieto, Maria T. Bengoechea-Alonso, Antonio Artigues, Ana Iriarte, and Marino Martinez-Carrión: The Nature of the Rate-limiting Steps in the Refolding of the Cofactor-dependent Protein Aspartate Aminotransferase
J. Biol. Chem. 2003 278: -49999. First Published on September 30, 2003; doi:10.1074/jbc.M309922200 [Abstract] [Full Text] [PDF]

Jan Ziegler, Heinrich Sticht, Ute C. Marx, Wolfgang Müller, Paul Rösch, and Stephan Schwarzinger: CD and NMR Studies of Prion Protein (PrP) Helix 1: NOVEL IMPLICATIONS FOR ITS ROLE IN THE PrP^C $->$ PrP^Sc CONVERSION PROCESS
J. Biol. Chem. 2003 278: -50181. First Published on September 2, 2003; doi:10.1074/jbc.M305234200 [Abstract] [Full Text] [PDF] Supplemental Data

Angelika Krebs, Patricia C. Edwards, Claudio Villa, Jade Li, and Gebhard F. X. Schertler: The Three-dimensional Structure of Bovine Rhodopsin Determined by Electron Cryomicroscopy
J. Biol. Chem. 2003 278: -50225. First Published on September 25, 2003; doi:10.1074/jbc.M307995200 [Abstract] [Full Text] [PDF]

Becky M. Miller, Miklós Nyitrai, Sanford I. Bernstein, and Michael A. Geeves: Kinetic Analysis of Drosophila Muscle Myosin Isoforms Suggests a Novel Mode of Mechanochemical Coupling
J. Biol. Chem. 2003 278: -50300. First Published on September 22, 2003; doi:10.1074/jbc.M308318200 [Abstract] [Full Text] [PDF]

Jonathan Heddle, David J. Scott, Satoru Unzai, Sam-Yong Park, and Jeremy R. H. Tame: Crystal Structures of the Liganded and Unliganded Nickel-binding Protein NikA from Escherichia coli
J. Biol. Chem. 2003 278: -50329. First Published on September 5, 2003; doi:10.1074/jbc.M307941200 [Abstract] [Full Text] [PDF]

Cong-Zhao Zhou, Ines Li de La Sierra-Gallay, Sophie Quevillon-Cheruel, Bruno Collinet, Philippe Minard, Karine Blondeau, Gilles Henckes, Robert Aufrère, Nicolas Leulliot, Marc Graille, Isabelle Sorel, Philippe Savarin, Françoise de la Torre, Anne Poupon, Joël Janin, and Herman van Tilbeurgh: Crystal Structure of the Yeast Phox Homology (PX) Domain Protein Grd19p Complexed to Phosphatidylinositol-3-phosphate
J. Biol. Chem. 2003 278: -50376. First Published on September 26, 2003; doi:10.1074/jbc.M304392200 [Abstract] [Full Text] [PDF]

Jianying Yang, Chittoor P. Swaminathan, Yuping Huang, Rongjin Guan, Sangwoo Cho, Michele C. Kieke, David M. Kranz, Roy A. Mariuzza, and Eric J. Sundberg: Dissecting Cooperative and Additive Binding Energetics in the Affinity Maturation Pathway of a Protein-Protein Interface
J. Biol. Chem. 2003 278: -50421. First Published on September 27, 2003; doi:10.1074/jbc.M306848200 [Abstract] [Full Text] [PDF]

Samantha M. Martins, Alex Chapeaurouge, and Sérgio T. Ferreira: Folding Intermediates of the Prion Protein Stabilized by Hydrostatic Pressure and Low Temperature
J. Biol. Chem. 2003 278: -50455. First Published on October 2, 2003; doi:10.1074/jbc.M307354200 [Abstract] [Full Text] [PDF]

Lucia Banci, Ivano Bertini, Simone Ciofi-Baffoni, Leonardo Gonnelli, and Xun-Cheng Su: Structural Basis for the Function of the N-terminal Domain of the ATPase CopA from Bacillus subtilis
J. Biol. Chem. 2003 278: -50513. First Published on September 27, 2003; doi:10.1074/jbc.M307389200 [Abstract] [Full Text] [PDF] Supplemental Data

Daniel J. Rigden and Mark J. Jedrzejas: Structures of Streptococcus pneumoniae Hyaluronate Lyase in Complex with Chondroitin and Chondroitin Sulfate Disaccharides: INSIGHTS INTO SPECIFICITY AND MECHANISM OF ACTION
J. Biol. Chem. 2003 278: -50606. First Published on September 30, 2003; doi:10.1074/jbc.M307596200 [Abstract] [Full Text] [PDF]

Lei Guo, Jody Groenendyk, Sylvia Papp, Monika Dabrowska, Barbara Knoblach, Cyril Kay, J. M. Robert Parker, Michal Opas, and Marek Michalak: Identification of an N-domain Histidine Essential for Chaperone Function in Calreticulin
J. Biol. Chem. 2003 278: -50653. First Published on October 1, 2003; doi:10.1074/jbc.M309497200 [Abstract] [Full Text] [PDF]

Dong Young Kim and Kyeong Kyu Kim: Crystal Structure of ClpX Molecular Chaperone from Helicobacter pylori
J. Biol. Chem. 2003 278: -50670. First Published on September 26, 2003; doi:10.1074/jbc.M305882200 [Abstract] [Full Text] [PDF]

Tongpil Min, Hiroyuki Kasahara, Diana L. Bedgar, Buhyun Youn, Paulraj K. Lawrence, David R. Gang, Steven C. Halls, HaJeung Park, Jacqueline L. Hilsenbeck, Laurence B. Davin, Norman G. Lewis, and ChulHee Kang: Crystal Structures of Pinoresinol-Lariciresinol and Phenylcoumaran Benzylic Ether Reductases and Their Relationship to Isoflavone Reductases
J. Biol. Chem. 2003 278: -50723. First Published on September 16, 2003; doi:10.1074/jbc.M308493200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

John P. Evans, Kyunghye Ahn, and Judith P. Klinman: Evidence That Dioxygen and Substrate Activation Are Tightly Coupled in Dopamine ${beta}$ -Monooxygenase: IMPLICATIONS FOR THE REACTIVE OXYGEN SPECIES
J. Biol. Chem. 2003 278: -49698. First Published on September 9, 2003; doi:10.1074/jbc.M300797200 [Abstract] [Full Text] [PDF]

Stephan Schilling, André J. Niestroj, Jens-Ulrich Rahfeld, Torsten Hoffmann, Michael Wermann, Katrin Zunkel, Claus Wasternack, and Hans-Ulrich Demuth: Identification of Human Glutaminyl Cyclase as a Metalloenzyme: POTENT INHIBITION BY IMIDAZOLE DERIVATIVES AND HETEROCYCLIC CHELATORS
J. Biol. Chem. 2003 278: -49779. First Published on September 30, 2003; doi:10.1074/jbc.M309077200 [Abstract] [Full Text] [PDF]

Eun-Suk Song, Maria Aparecida Juliano, Luiz Juliano, and Louis B. Hersh: Substrate Activation of Insulin-degrading Enzyme (Insulysin): A POTENTIAL TARGET FOR DRUG DEVELOPMENT
J. Biol. Chem. 2003 278: -49794. First Published on October 2, 2003; doi:10.1074/jbc.M308983200 [Abstract] [Full Text] [PDF]

Young Min Jang, Dae Won Kim, Tae-Cheon Kang, Moo Ho Won, Nam-In Baek, Byung Jo Moon, Soo Young Choi, and Oh-Shin Kwon: Human Pyridoxal Phosphatase: MOLECULAR CLONING, FUNCTIONAL EXPRESSION, AND TISSUE DISTRIBUTION
J. Biol. Chem. 2003 278: -50046. First Published on September 30, 2003; doi:10.1074/jbc.M309619200 [Abstract] [Full Text] [PDF]

Jane K. McIninch, James D. McIninch, and Sheldon W. May: Catalysis, Stereochemistry, and Inhibition of Ureidoglycolate Lyase
J. Biol. Chem. 2003 278: -50100. First Published on September 23, 2003; doi:10.1074/jbc.M303828200 [Abstract] [Full Text] [PDF]

Xiaoli Shi, Christopher Stoj, Annette Romeo, Daniel J. Kosman, and Zhiwu Zhu: Fre1p Cu²⁺ Reduction and Fet3p Cu¹⁺ Oxidation Modulate Copper Toxicity in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: -50315. First Published on September 3, 2003; doi:10.1074/jbc.M307019200 [Abstract] [Full Text] [PDF]

Alexander Zhyvoloup, Ivan Nemazanyy, Ganna Panasyuk, Taras Valovka, Tim Fenton, Heike Rebholz, Mong-Lien Wang, Richard Foxon, Valeriy Lyzogubov, Vasylij Usenko, Ramziya Kyyamova, Olena Gorbenko, Genadiy Matsuka, Valeriy Filonenko, and Ivan T. Gout: Subcellular Localization and Regulation of Coenzyme A Synthase
J. Biol. Chem. 2003 278: -50321. First Published on September 26, 2003; doi:10.1074/jbc.M307763200 [Abstract] [Full Text] [PDF]

Stéphanie Gobin, Laure Thuillier, Gerwald Jogl, Audrey Faye, Liang Tong, Mihaiti Chi, Jean-Paul Bonnefont, Jean Girard, and Carina Prip-Buus: Functional and Structural Basis of Carnitine Palmitoyltransferase 1A Deficiency
J. Biol. Chem. 2003 278: -50434. First Published on September 29, 2003; doi:10.1074/jbc.M310130200 [Abstract] [Full Text] [PDF]

Daniel E. Pilloff and Thomas S. Leyh: Allosteric and Catalytic Functions of the PP_i-binding Motif in the ATP Sulfurylase-GTPase System
J. Biol. Chem. 2003 278: -50441. First Published on September 23, 2003; doi:10.1074/jbc.M306897200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Delphine G. Bernard, Stéphane T. Gabilly, Geneviève Dujardin, Sabeeha Merchant, and Patrice P. Hamel: Overlapping Specificities of the Mitochondrial Cytochrome c and c₁ Heme Lyases
J. Biol. Chem. 2003 278: -49742. First Published on September 26, 2003; doi:10.1074/jbc.M308881200 [Abstract] [Full Text] [PDF] Supplemental Data

Andrea M. Cesura, Emmanuel Pinard, Robert Schubenel, Valerie Goetschy, Arno Friedlein, Hanno Langen, Peter Polcic, Michael A. Forte, Paolo Bernardi, and John A. Kemp: The Voltage-dependent Anion Channel Is the Target for a New Class of Inhibitors of the Mitochondrial Permeability Transition Pore
J. Biol. Chem. 2003 278: -49818. First Published on September 2, 2003; doi:10.1074/jbc.M304748200 [Abstract] [Full Text] [PDF]

Ahmad L. Subhi, Paula Diegelman, Carl W. Porter, Baiqing Tang, Zichun J. Lu, George D. Markham, and Warren D. Kruger: Methylthioadenosine Phosphorylase Regulates Ornithine Decarboxylase by Production of Downstream Metabolites
J. Biol. Chem. 2003 278: -49873. First Published on September 23, 2003; doi:10.1074/jbc.M308451200 [Abstract] [Full Text] [PDF]

Jian-Su Shao, Su-Li Cheng, Nichole Charlton-Kachigian, Arleen P. Loewy, and Dwight A. Towler: Teriparatide (Human Parathyroid Hormone (1–34)) Inhibits Osteogenic Vascular Calcification in Diabetic Low Density Lipoprotein Receptor-deficient Mice
J. Biol. Chem. 2003 278: -50202. First Published on September 22, 2003; doi:10.1074/jbc.M308825200 [Abstract] [Full Text] [PDF]

Toshiaki Imagawa, Shunji Kaya, and Kazuya Taniguchi: The Amino Acid Sequence ⁴⁴²GDASE⁴⁴⁶ in Na/K-ATPase Is an Important Motif in Forming the High and Low Affinity ATP Binding Pockets
J. Biol. Chem. 2003 278: -50292. First Published on September 30, 2003; doi:10.1074/jbc.M309833200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Marjut Borgenström, Markku Jalkanen, and Markku Salmivirta: Sulfated Derivatives of Escherichia coli K5 Polysaccharides as Modulators of Fibroblast Growth Factor Signaling
J. Biol. Chem. 2003 278: -49889. First Published on September 26, 2003; doi:10.1074/jbc.M304208200 [Abstract] [Full Text] [PDF]

Gerhard Sengle, Birgit Kobbe, Matthias Mörgelin, Mats Paulsson, and Raimund Wagener: Identification and Characterization of AMACO, a New Member of the von Willebrand Factor A-like Domain Protein Superfamily with a Regulated Expression in the Kidney
J. Biol. Chem. 2003 278: -50249. First Published on September 23, 2003; doi:10.1074/jbc.M307794200 [Abstract] [Full Text] [PDF]

Michelle Dawson, Denis Wirtz, and Justin Hanes: Enhanced Viscoelasticity of Human Cystic Fibrotic Sputum Correlates with Increasing Microheterogeneity in Particle Transport
J. Biol. Chem. 2003 278: -50401. First Published on September 17, 2003; doi:10.1074/jbc.M309026200 [Abstract] [Full Text] [PDF]

Tomohiro Kozaki, Yoshito Matsui, Jianguo Gu, Ryoko Nishiuchi, Nobuo Sugiura, Koji Kimata, Keiichi Ozono, Hideki Yoshikawa, and Kiyotoshi Sekiguchi: Recombinant Expression and Characterization of a Novel Fibronectin Isoform Expressed in Cartilaginous Tissues
J. Biol. Chem. 2003 278: -50553. First Published on October 2, 2003; doi:10.1074/jbc.M307432200 [Abstract] [Full Text] [PDF] Supplemental Data

Sugiko Futaki, Yoshitaka Hayashi, Megumi Yamashita, Ken Yagi, Hidemasa Bono, Yoshihide Hayashizaki, Yasushi Okazaki, and Kiyotoshi Sekiguchi: Molecular Basis of Constitutive Production of Basement Membrane Components: GENE EXPRESSION PROFILES OF ENGELBRETH-HOLM-SWARM TUMOR AND F9 EMBRYONAL CARCINOMA CELLS
J. Biol. Chem. 2003 278: -50701. First Published on September 10, 2003; doi:10.1074/jbc.M304985200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Ronit Sharon, Ifat Bar-Joseph, Gudrun E. Mirick, Charles N. Serhan, and Dennis J. Selkoe: Altered Fatty Acid Composition of Dopaminergic Neurons Expressing ${alpha}$ -Synuclein and Human Brains with ${alpha}$ -Synucleinopathies
J. Biol. Chem. 2003 278: -49881. First Published on September 23, 2003; doi:10.1074/jbc.M309127200 [Abstract] [Full Text] [PDF]

Yoshichika Kawai, Atsunori Furuhata, Shinya Toyokuni, Yasuaki Aratani, and Koji Uchida: Formation of Acrolein-derived 2'-Deoxyadenosine Adduct in an Iron-induced Carcinogenesis Model
J. Biol. Chem. 2003 278: -50354. First Published on September 30, 2003; doi:10.1074/jbc.M309057200 [Abstract] [Full Text] [PDF] Supplemental Data

Membrane Transport, Structure, Function, and Biogenesis:

Stiina Välimäki, Anders Höög, Catharina Larsson, Lars-Ove Farnebo, and Robert Bränström: High Extracellular Ca²⁺ Hyperpolarizes Human Parathyroid Cells via Ca²⁺-activated K⁺ Channels
J. Biol. Chem. 2003 278: -49690. First Published on October 1, 2003; doi:10.1074/jbc.M310595200 [Abstract] [Full Text] [PDF]

Jutta Nesper, Chris M. D. Hill, Anne Paiment, George Harauz, Konstantinos Beis, James H. Naismith, and Chris Whitfield: Translocation of Group 1 Capsular Polysaccharide in Escherichia coli Serotype K30: STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE OUTER MEMBRANE LIPOPROTEIN Wza
J. Biol. Chem. 2003 278: -49772. First Published on September 30, 2003; doi:10.1074/jbc.M308775200 [Abstract] [Full Text] [PDF]

M. Tom Sebulsky, Brian H. Shilton, Craig D. Speziali, and David E. Heinrichs: The Role of FhuD2 in Iron(III)-Hydroxamate Transport in Staphylococcus aureus: DEMONSTRATION THAT FhuD2 BINDS IRON(III)-HYDROXAMATES BUT WITH MINIMAL CONFORMATIONAL CHANGE AND IMPLICATION OF MUTATIONS ON TRANSPORT
J. Biol. Chem. 2003 278: -49900. First Published on September 26, 2003; doi:10.1074/jbc.M305073200 [Abstract] [Full Text] [PDF]

F. Javier Pérez-Victoria, Francisco Gamarro, Marc Ouellette, and Santiago Castanys: Functional Cloning of the Miltefosine Transporter: A NOVEL P-TYPE PHOSPHOLIPID TRANSLOCASE FROM LEISHMANIA INVOLVED IN DRUG RESISTANCE
J. Biol. Chem. 2003 278: -49971. First Published on September 27, 2003; doi:10.1074/jbc.M308352200 [Abstract] [Full Text] [PDF]

Nico Melzer, Alexander Biela, and Christoph Fahlke: Glutamate Modifies Ion Conduction and Voltage-dependent Gating of Excitatory Amino Acid Transporter-associated Anion Channels
J. Biol. Chem. 2003 278: -50119. First Published on September 23, 2003; doi:10.1074/jbc.M307990200 [Abstract] [Full Text] [PDF]

Wei Zhang, Mikhail Bogdanov, Jing Pi, A. James Pittard, and William Dowhan: Reversible Topological Organization within a Polytopic Membrane Protein Is Governed by a Change in Membrane Phospholipid Composition
J. Biol. Chem. 2003 278: -50135. First Published on October 1, 2003; doi:10.1074/jbc.M309840200 [Abstract] [Full Text] [PDF]

Tip W. Loo, M. Claire Bartlett, and David M. Clarke: Methanethiosulfonate Derivatives of Rhodamine and Verapamil Activate Human P-glycoprotein at Different Sites
J. Biol. Chem. 2003 278: -50141. First Published on October 1, 2003; doi:10.1074/jbc.M310448200 [Abstract] [Full Text] [PDF]

Markus Ritter, Andrea Ravasio, Martin Jakab, Sabine Chwatal, Johannes Fürst, Andreas Laich, Martin Gschwentner, Sara Signorelli, Carmen Burtscher, Sonja Eichmüller, and Markus Paulmichl: Cell Swelling Stimulates Cytosol to Membrane Transposition of ICln
J. Biol. Chem. 2003 278: -50174. First Published on September 11, 2003; doi:10.1074/jbc.M300374200 [Abstract] [Full Text] [PDF]

Terra B. Potocky, Anant K. Menon, and Samuel H. Gellman: Cytoplasmic and Nuclear Delivery of a TAT-derived Peptide and a ${beta}$ -Peptide after Endocytic Uptake into HeLa Cells
J. Biol. Chem. 2003 278: -50194. First Published on September 29, 2003; doi:10.1074/jbc.M308719200 [Abstract] [Full Text] [PDF]

Ki Ho Park, Manish Chhowalla, Zafar Iqbal, and Federico Sesti: Single-walled Carbon Nanotubes Are a New Class of Ion Channel Blockers
J. Biol. Chem. 2003 278: -50216. First Published on September 30, 2003; doi:10.1074/jbc.M310216200 [Abstract] [Full Text] [PDF]

Yuping Gong, Muralikrishna Duvvuri, and Jeffrey P. Krise: Separate Roles for the Golgi Apparatus and Lysosomes in the Sequestration of Drugs in the Multidrug-resistant Human Leukemic Cell Line HL-60
J. Biol. Chem. 2003 278: -50239. First Published on September 30, 2003; doi:10.1074/jbc.M306606200 [Abstract] [Full Text] [PDF]

Alexandra Makarova, Irina Mikhailenko, Thomas H. Bugge, Karin List, Daniel A. Lawrence, and Dudley K. Strickland: The Low Density Lipoprotein Receptor-related Protein Modulates Protease Activity in the Brain by Mediating the Cellular Internalization of Both Neuroserpin and Neuroserpin-Tissue-type Plasminogen Activator Complexes
J. Biol. Chem. 2003 278: -50258. First Published on September 30, 2003; doi:10.1074/jbc.M309150200 [Abstract] [Full Text] [PDF]

Niall J. Lennon, Alvin Kho, Brian J. Bacskai, Sarah L. Perlmutter, Bradley T. Hyman, and Robert H. Brown, Jr.: Dysferlin Interacts with Annexins A1 and A2 and Mediates Sarcolemmal Wound-healing
J. Biol. Chem. 2003 278: -50473. First Published on September 23, 2003; doi:10.1074/jbc.M307247200 [Abstract] [Full Text] [PDF] Supplemental Data

Hermia Ip, Kelly Stratton, Helen Zgurskaya, and Jun Liu: pH-induced Conformational Changes of AcrA, the Membrane Fusion Protein of Escherichia coli Multidrug Efflux System
J. Biol. Chem. 2003 278: -50482. First Published on October 1, 2003; doi:10.1074/jbc.M305152200 [Abstract] [Full Text] [PDF]

Thomas W. Claydon, Samy Y. Makary, Katharine M. Dibb, and Mark R. Boyett: The Selectivity Filter May Act as the Agonist-activated Gate in the G Protein-activated Kir3.1/Kir3.4 K⁺ Channel
J. Biol. Chem. 2003 278: -50663. First Published on October 2, 2003; doi:10.1074/jbc.M308183200 [Abstract] [Full Text] [PDF]

Shuichi Nishikubo, Masaru Ohara, Yoko Ueno, Masae Ikura, Hidemi Kurihara, Hitoshi Komatsuzawa, Eric Oswald, and Motoyuki Sugai: An N-terminal Segment of the Active Component of the Bacterial Genotoxin Cytolethal Distending Toxin B (CDTB) Directs CDTB into the Nucleus
J. Biol. Chem. 2003 278: -50681. First Published on August 28, 2003; doi:10.1074/jbc.M305062200 [Abstract] [Full Text] [PDF]

Alain J. Labro, Adam L. Raes, Iris Bellens, Natacha Ottschytsch, and Dirk J. Snyders: Gating of Shaker-type Channels Requires the Flexibility of S6 Caused by Prolines
J. Biol. Chem. 2003 278: -50731. First Published on September 17, 2003; doi:10.1074/jbc.M306097200 [Abstract] [Full Text] [PDF] Supplemental data

Mechanisms Of Signal Transduction:

Edwin C. Thrower, Chi Un Choe, Seung Ho So, Soung Hoo Jeon, Barbara E. Ehrlich, and Seung Hyun Yoo: A Functional Interaction between Chromogranin B and the Inositol 1,4,5-Trisphosphate Receptor/Ca²⁺ Channel
J. Biol. Chem. 2003 278: -49706. First Published on September 23, 2003; doi:10.1074/jbc.M309307200 [Abstract] [Full Text] [PDF]

Frédéric Baert, Jean-François Bodart, Béatrice Bocquet-Muchembled, Arlette Lescuyer-Rousseau, and Jean-Pierre Vilain: Xp42^Mpk1 Activation Is Not Required for Germinal Vescicle Breakdown but for Raf Complete Phosphorylation in Insulin-stimulated Xenopus Oocytes
J. Biol. Chem. 2003 278: -49720. First Published on September 24, 2003; doi:10.1074/jbc.M308067200 [Abstract] [Full Text] [PDF]

Hiroyuki Oshiumi, Miwa Sasai, Kyoko Shida, Takashi Fujita, Misako Matsumoto, and Tsukasa Seya: TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-like Receptor 4 TICAM-1 That Induces Interferon- ${beta}$
J. Biol. Chem. 2003 278: -49762. First Published on September 30, 2003; doi:10.1074/jbc.M305820200 [Abstract] [Full Text] [PDF] Supplemental Data

Ka-Chun Suen, Man-Shan Yu, Kwok-Fai So, Raymond Chuen-Chung Chang, and Jacques Hugon: Upstream Signaling Pathways Leading to the Activation of Double-stranded RNA-dependent Serine/Threonine Protein Kinase in ${beta}$ -Amyloid Peptide Neurotoxicity
J. Biol. Chem. 2003 278: -49827. First Published on September 15, 2003; doi:10.1074/jbc.M306503200 [Abstract] [Full Text] [PDF]

Caroline Diveu, Eric Lelièvre, David Perret, Anne-Hélène Lagrue Lak-Hal, Josy Froger, Catherine Guillet, Sylvie Chevalier, François Rousseau, Amy Wesa, Laurence Preisser, Marie Chabbert, Jean-François Gauchat, Anne Galy, Hugues Gascan, and Alain Morel: GPL, a Novel Cytokine Receptor Related to GP130 and Leukemia Inhibitory Factor Receptor
J. Biol. Chem. 2003 278: -49859. First Published on September 22, 2003; doi:10.1074/jbc.M307286200 [Abstract] [Full Text] [PDF]

Annie-Carole Tosello-Trampont, Kumiko Nakada-Tsukui, and Kodi S. Ravichandran: Engulfment of Apoptotic Cells Is Negatively Regulated by Rho-mediated Signaling
J. Biol. Chem. 2003 278: -49919. First Published on September 26, 2003; doi:10.1074/jbc.M306079200 [Abstract] [Full Text] [PDF] Supplemental Data

Songling Liu, Richard T. Premont, Christopher D. Kontos, Jianhua Huang, and Don C. Rockey: Endothelin-1 Activates Endothelial Cell Nitric-oxide Synthase via Heterotrimeric G-protein ${beta}$ ${gamma}$ Subunit Signaling to Protein Kinase B/Akt
J. Biol. Chem. 2003 278: -49935. First Published on September 30, 2003; doi:10.1074/jbc.M306930200 [Abstract] [Full Text] [PDF]

Judith Haendeler, Guoyong Yin, Yukihiro Hojo, Yuji Saito, Matthew Melaragno, Chen Yan, Virendra K. Sharma, Manfred Heller, Ruedi Aebersold, and Bradford C. Berk: GIT1 Mediates Src-dependent Activation of Phospholipase C ${gamma}$ by Angiotensin II and Epidermal Growth Factor
J. Biol. Chem. 2003 278: -49944. First Published on September 30, 2003; doi:10.1074/jbc.M307317200 [Abstract] [Full Text] [PDF]

Mayte Montero, Carmen D. Lobatón, Silvia Gutierrez-Fernández, Alfredo Moreno, and Javier Alvarez: Modulation of Histamine-induced Ca²⁺ Release by Protein Kinase C: EFFECTS ON CYTOSOLIC AND MITOCHONDRIAL [Ca²⁺] PEAKS
J. Biol. Chem. 2003 278: -49979. First Published on September 30, 2003; doi:10.1074/jbc.M308378200 [Abstract] [Full Text] [PDF]

Paola Casarosa, Yvonne K. Gruijthuijsen, Detlef Michel, Patrick S. Beisser, Jens Holl, Carlos P. Fitzsimons, Dennis Verzijl, Cathrien A. Bruggeman, Thomas Mertens, Rob Leurs, Cornelis Vink, and Martine J. Smit: Constitutive Signaling of the Human Cytomegalovirus-encoded Receptor UL33 Differs from That of Its Rat Cytomegalovirus Homolog R33 by Promiscuous Activation of G Proteins of the G_q, G_i, and G_s Classes
J. Biol. Chem. 2003 278: -50023. First Published on September 30, 2003; doi:10.1074/jbc.M306530200 [Abstract] [Full Text] [PDF]

Carlo Iavarone, Annunziata Catania, Maria Julia Marinissen, Roberta Visconti, Mario Acunzo, Carolina Tarantino, M. Stella Carlomagno, Carmelo B. Bruni, J. Silvio Gutkind, and Mario Chiariello: The Platelet-derived Growth Factor Controls c-myc Expression through a JNK- and AP-1-dependent Signaling Pathway
J. Biol. Chem. 2003 278: -50030. First Published on September 30, 2003; doi:10.1074/jbc.M308617200 [Abstract] [Full Text] [PDF]

Robyn Richie-Jannetta, Sharron H. Francis, and Jackie D. Corbin: Dimerization of cGMP-dependent Protein Kinase I ${beta}$ Is Mediated by an Extensive Amino-terminal Leucine Zipper Motif, and Dimerization Modulates Enzyme Function
J. Biol. Chem. 2003 278: -50079. First Published on August 21, 2003; doi:10.1074/jbc.M306796200 [Abstract] [Full Text] [PDF]

Durga P. Mohapatra and Carla Nau: Desensitization of Capsaicin-activated Currents in the Vanilloid Receptor TRPV1 Is Decreased by the Cyclic AMP-dependent Protein Kinase Pathway
J. Biol. Chem. 2003 278: -50090. First Published on September 23, 2003; doi:10.1074/jbc.M306619200 [Abstract] [Full Text] [PDF]

Nathan L. Absalom, Trevor M. Lewis, Warren Kaplan, Kerrie D. Pierce, and Peter R. Schofield: Role of Charged Residues in Coupling Ligand Binding and Channel Activation in the Extracellular Domain of the Glycine Receptor
J. Biol. Chem. 2003 278: -50157. First Published on October 2, 2003; doi:10.1074/jbc.M305357200 [Abstract] [Full Text] [PDF]

Luying Peng, Tooraj Mirshahi, Hailin Zhang, Jeanne P. Hirsch, and Diomedes E. Logothetis: Critical Determinants of the G Protein ${gamma}$ Subunits in the G ${beta}$ ${gamma}$ Stimulation of G Protein-activated Inwardly Rectifying Potassium (GIRK) Channel Activity
J. Biol. Chem. 2003 278: -50211. First Published on September 15, 2003; doi:10.1074/jbc.M308299200 [Abstract] [Full Text] [PDF]

Hiroaki Murata, Yoshito Ihara, Hajime Nakamura, Junji Yodoi, Koji Sumikawa, and Takahito Kondo: Glutaredoxin Exerts an Antiapoptotic Effect by Regulating the Redox State of Akt
J. Biol. Chem. 2003 278: -50233. First Published on October 1, 2003; doi:10.1074/jbc.M310171200 [Abstract] [Full Text] [PDF]

Teresita Bellido, A. Afshan Ali, Lilian I. Plotkin, Qiang Fu, Igor Gubrij, Paula K. Roberson, Robert S. Weinstein, Charles A. O'Brien, Stavros C. Manolagas, and Robert L. Jilka: Proteasomal Degradation of Runx2 Shortens Parathyroid Hormone-induced Anti-apoptotic Signaling in Osteoblasts: A PUTATIVE EXPLANATION FOR WHY INTERMITTENT ADMINISTRATION IS NEEDED FOR BONE ANABOLISM
J. Biol. Chem. 2003 278: -50272. First Published on October 1, 2003; doi:10.1074/jbc.M307444200 [Abstract] [Full Text] [PDF] Supplemental Data

Shiqin Xiong, Qiuhui Zhao, Zhili Rong, Guanrong Huang, Yiling Huang, Peila Chen, Shuping Zhang, Li Liu, and Zhijie Chang: hSef Inhibits PC-12 Cell Differentiation by Interfering with Ras-Mitogen-activated Protein Kinase MAPK Signaling
J. Biol. Chem. 2003 278: -50282. First Published on September 4, 2003; doi:10.1074/jbc.M306936200 [Abstract] [Full Text] [PDF]

Young-Mi Ham, Joon-Seok Choi, Kwang-Hoon Chun, Sang-Hoon Joo, and Seung-Ki Lee: The c-Jun N-terminal Kinase 1 Activity Is Differentially Regulated by Specific Mechanisms during Apoptosis
J. Biol. Chem. 2003 278: -50337. First Published on September 26, 2003; doi:10.1074/jbc.M302997200 [Abstract] [Full Text] [PDF]

Ayako Miyakawa-Naito, Per Uhlén, Mark Lal, Oleg Aizman, Katsuhiko Mikoshiba, Hjalmar Brismar, Sergey Zelenin, and Anita Aperia: Cell Signaling Microdomain with Na,K-ATPase and Inositol 1,4,5-Trisphosphate Receptor Generates Calcium Oscillations
J. Biol. Chem. 2003 278: -50361. First Published on August 28, 2003; doi:10.1074/jbc.M305378200 [Abstract] [Full Text] [PDF]

Shreevrat Goenka, Clinton Marlar, Ulrike Schindler, and Mark Boothby: Differential Roles of C-terminal Activation Motifs in the Establishment of Stat6 Transcriptional Specificity
J. Biol. Chem. 2003 278: -50370. First Published on September 30, 2003; doi:10.1074/jbc.M305854200 [Abstract] [Full Text] [PDF]

Mara Fornaro, Janet Plescia, Sophie Chheang, Giovanni Tallini, Yong-M. Zhu, Michael King, Dario C. Altieri, and Lucia R. Languino: Fibronectin Protects Prostate Cancer Cells from Tumor Necrosis Factor- ${alpha}$ -induced Apoptosis via the AKT/Survivin Pathway
J. Biol. Chem. 2003 278: -50411. First Published on September 30, 2003; doi:10.1074/jbc.M307627200 [Abstract] [Full Text] [PDF]

Paulo Matos, John G. Collard, and Peter Jordan: Tumor-related Alternatively Spliced Rac1b Is Not Regulated by Rho-GDP Dissociation Inhibitors and Exhibits Selective Downstream Signaling
J. Biol. Chem. 2003 278: -50448. First Published on September 23, 2003; doi:10.1074/jbc.M308215200 [Abstract] [Full Text] [PDF]

Daniel N. Streblow, Jennifer Vomaske, Patsy Smith, Ryan Melnychuk, Laurel Hall, Dora Pancheva, Martine Smit, Paola Casarosa, David D. Schlaepfer, and Jay A. Nelson: Human Cytomegalovirus Chemokine Receptor US28-induced Smooth Muscle Cell Migration Is Mediated by Focal Adhesion Kinase and Src
J. Biol. Chem. 2003 278: -50465. First Published on September 22, 2003; doi:10.1074/jbc.M307936200 [Abstract] [Full Text] [PDF]

Julia A. Yaglom, Daryoush Ekhterae, Vladimir L. Gabai, and Michael Y. Sherman: Regulation of Necrosis of H9c2 Myogenic Cells upon Transient Energy Deprivation: RAPID DEENERGIZATION OF MITOCHONDRIA PRECEDES NECROSIS AND IS CONTROLLED BY REACTIVE OXYGEN SPECIES, STRESS KINASE JNK, HSP72, AND ARC
J. Biol. Chem. 2003 278: -50496. First Published on September 30, 2003; doi:10.1074/jbc.M306903200 [Abstract] [Full Text] [PDF]

Silvia Gines, Elena Ivanova, Ihn-Sik Seong, Carlos A. Saura, and Marcy E. MacDonald: Enhanced Akt Signaling Is an Early Pro-survival Response That Reflects N-Methyl-D-aspartate Receptor Activation in Huntington's Disease Knock-in Striatal Cells
J. Biol. Chem. 2003 278: -50522. First Published on October 1, 2003; doi:10.1074/jbc.M309348200 [Abstract] [Full Text] [PDF]

Chenglong Li, Paula S. Norris, Chao-Zhou Ni, Marnie L. Havert, Elizabeth M. Chiong, Bonnie R. Tran, Edelmira Cabezas, John C. Reed, Arnold C. Satterthwait, Carl F. Ware, and Kathryn R. Ely: Structurally Distinct Recognition Motifs in Lymphotoxin- ${beta}$ Receptor and CD40 for Tumor Necrosis Factor Receptor-associated Factor (TRAF)-mediated Signaling
J. Biol. Chem. 2003 278: -50529. First Published on September 29, 2003; doi:10.1074/jbc.M309381200 [Abstract] [Full Text] [PDF]

Janna E. Slessareva, Hongzheng Ma, Karyn M. Depree, Lori A. Flood, Hyunsu Bae, Theresa M. Cabrera-Vera, Heidi E. Hamm, and Stephen G. Graber: Closely Related G-protein-coupled Receptors Use Multiple and Distinct Domains on G-protein ${alpha}$ -Subunits for Selective Coupling
J. Biol. Chem. 2003 278: -50536. First Published on October 2, 2003; doi:10.1074/jbc.M304417200 [Abstract] [Full Text] [PDF]

Darerca Owen, Peter N. Lowe, Daniel Nietlispach, C. Elaine Brosnan, Dimitri Y. Chirgadze, Peter J. Parker, Tom L. Blundell, and Helen R. Mott: Molecular Dissection of the Interaction between the Small G Proteins Rac1 and RhoA and Protein Kinase C-related Kinase 1 (PRK1)
J. Biol. Chem. 2003 278: -50587. First Published on September 26, 2003; doi:10.1074/jbc.M304313200 [Abstract] [Full Text] [PDF]

Omar Tliba, Samira Tliba, Chien Da Huang, Rebecca K. Hoffman, Peter DeLong, Reynold A. Panettieri, Jr., and Yassine Amrani: Tumor Necrosis Factor ${alpha}$ Modulates Airway Smooth Muscle Function via the Autocrine Action of Interferon ${beta}$
J. Biol. Chem. 2003 278: -50623. First Published on September 30, 2003; doi:10.1074/jbc.M303680200 [Abstract] [Full Text] [PDF]

Moon-Taek Park, Jung-A Choi, Min-Jeong Kim, Hong-Duck Um, Sangwoo Bae, Chang-Mo Kang, Chul-Koo Cho, Seongman Kang, Hee Yong Chung, Yun-Sil Lee, and Su-Jae Lee: Suppression of Extracellular Signal-related Kinase and Activation of p38 MAPK Are Two Critical Events Leading to Caspase-8- and Mitochondria-mediated Cell Death in Phytosphingosine-treated Human Cancer Cells
J. Biol. Chem. 2003 278: -50634. First Published on September 30, 2003; doi:10.1074/jbc.M309011200 [Abstract] [Full Text] [PDF]

Cristina Croci, Heinrich Sticht, Johann Helmut Brandstätter, and Ralf Enz: Group I Metabotropic Glutamate Receptors Bind to Protein Phosphatase 1C: MAPPING AND MODELING OF INTERACTING SEQUENCES
J. Biol. Chem. 2003 278: -50690. First Published on September 30, 2003; doi:10.1074/jbc.M305764200 [Abstract] [Full Text] [PDF]

Thomas Hon, Athena Dodd, Reinhard Dirmeier, Nadia Gorman, Peter R. Sinclair, Li Zhang, and Robert O. Poyton: A Mechanism of Oxygen Sensing in Yeast: MULTIPLE OXYGEN-RESPONSIVE STEPS IN THE HEME BIOSYNTHETIC PATHWAY AFFECT Hap1 ACTIVITY
J. Biol. Chem. 2003 278: -50780. First Published on September 25, 2003; doi:10.1074/jbc.M303677200 [Abstract] [Full Text] [PDF]

Pilar Muñoz, María-del-Carmen Navarro, Esther J. Pavón, Javier Salmerón, Fabio Malavasi, Jaime Sancho, and Mercedes Zubiaur: CD38 Signaling in T Cells Is Initiated within a Subset of Membrane Rafts Containing Lck and the CD3- ${zeta}$ Subunit of the T Cell Antigen Receptor
J. Biol. Chem. 2003 278: -50802. First Published on September 30, 2003; doi:10.1074/jbc.M308034200 [Abstract] [Full Text] [PDF]

Tsu-Shuen Tsao, Eva Tomas, Heather E. Murrey, Christopher Hug, David H. Lee, Neil B. Ruderman, John E. Heuser, and Harvey F. Lodish: Role of Disulfide Bonds in Acrp30/Adiponectin Structure and Signaling Specificity: DIFFERENT OLIGOMERS ACTIVATE DIFFERENT SIGNAL TRANSDUCTION PATHWAYS
J. Biol. Chem. 2003 278: -50817. First Published on September 30, 2003; doi:10.1074/jbc.M309469200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Wen Bu and Li-Kuo Su: Characterization of Functional Domains of Human EB1 Family Proteins
J. Biol. Chem. 2003 278: -49731. First Published on September 26, 2003; doi:10.1074/jbc.M306194200 [Abstract] [Full Text] [PDF]

Jianqiao Xiao, Poonam Jethanandani, Barry L. Ziober, and Randall H. Kramer: Regulation of ${alpha}$ ₇ Integrin Expression during Muscle Differentiation
J. Biol. Chem. 2003 278: -49788. First Published on October 1, 2003; doi:10.1074/jbc.M308542200 [Abstract] [Full Text] [PDF]

Andrew Sunters, Silvia Fernández de Mattos, Marie Stahl, Jan J. Brosens, Georgia Zoumpoulidou, Catherine A. Saunders, Paul J. Coffer, René H. Medema, R. Charles Coombes, and Eric W.-F. Lam: FoxO3a Transcriptional Regulation of Bim Controls Apoptosis in Paclitaxel-treated Breast Cancer Cell Lines
J. Biol. Chem. 2003 278: -49805. First Published on October 3, 2003; doi:10.1074/jbc.M309523200 [Abstract] [Full Text] [PDF]

Xuequn Chen, Stephen A. Ernst, and John A. Williams: Dominant Negative Rab3D Mutants Reduce GTP-bound Endogenous Rab3D in Pancreatic Acini
J. Biol. Chem. 2003 278: -50060. First Published on September 30, 2003; doi:10.1074/jbc.M309910200 [Abstract] [Full Text] [PDF]

Ryo Ueta, Ayako Fukunaka, and Yuko Yamaguchi-Iwai: Pse1p Mediates the Nuclear Import of the Iron-responsive Transcription Factor Aft1p in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: -50127. First Published on October 1, 2003; doi:10.1074/jbc.M305046200 [Abstract] [Full Text] [PDF]

Julia Kirshner, Detlef Schumann, and John E. Shively: CEACAM1, a Cell-Cell Adhesion Molecule, Directly Associates with Annexin II in a Three-dimensional Model of Mammary Morphogenesis
J. Biol. Chem. 2003 278: -50345. First Published on September 30, 2003; doi:10.1074/jbc.M309115200 [Abstract] [Full Text] [PDF]

Naoyuki Fukuda, Masatoshi Ichihara, Takatoshi Morinaga, Kumi Kawai, Hironori Hayashi, Yoshiki Murakumo, Seiichi Matsuo, and Masahide Takahashi: Identification of a Novel Glial Cell Line-derived Neurotrophic Factor-inducible Gene Required for Renal Branching Morphogenesis
J. Biol. Chem. 2003 278: -50392. First Published on September 30, 2003; doi:10.1074/jbc.M309629200 [Abstract] [Full Text] [PDF]

Roger A. Moorehead, Carlo V. Hojilla, Ian De Belle, Geoffrey A. Wood, Jimmie E. Fata, Eileen D. Adamson, Katrina L. M. Watson, Dylan R. Edwards, and Rama Khokha: Insulin-like Growth Factor-II Regulates PTEN Expression in the Mammary Gland
J. Biol. Chem. 2003 278: -50427. First Published on September 29, 2003; doi:10.1074/jbc.M306894200 [Abstract] [Full Text] [PDF]

Davide Comoletti, Robyn Flynn, Lori L. Jennings, Alexander Chubykin, Takehito Matsumura, Hana Hasegawa, Thomas C. Südhof, and Palmer Taylor: Characterization of the Interaction of a Recombinant Soluble Neuroligin-1 with Neurexin-1 ${beta}$
J. Biol. Chem. 2003 278: -50505. First Published on September 30, 2003; doi:10.1074/jbc.M306803200 [Abstract] [Full Text] [PDF]

Mark Gilchrist, Christian Hesslinger, and A. Dean Befus: Tetrahydrobiopterin, a Critical Factor in the Production and Role of Nitric Oxide in Mast Cells
J. Biol. Chem. 2003 278: -50614. First Published on September 26, 2003; doi:10.1074/jbc.M307777200 [Abstract] [Full Text] [PDF] Supplemental Data

Siu-Wah Chung, John A. Arnott, Yizeng Yang, and Peter M. C. Wong: Presence of Prepackaged mRNA in Virions of DNA Adenovirus
J. Biol. Chem. 2003 278: -50640. First Published on September 30, 2003; doi:10.1074/jbc.M309945200 [Abstract] [Full Text] [PDF]

Ignasi Forné, Montserrat Carrascal, Luis Martinez-Lostao, Joaquin Abian, Jose Luis Rodriguez-Sánchez, and Candido Juarez: Identification of the Autoantigen HB as the Barrier-to-Autointegration Factor
J. Biol. Chem. 2003 278: -50644. First Published on October 1, 2003; doi:10.1074/jbc.M308531200 [Abstract] [Full Text] [PDF]

Ilaria Cascone, Enrico Giraudo, Francesca Caccavari, Lucia Napione, Elisa Bertotti, John G. Collard, Guido Serini, and Federico Bussolino: Temporal and Spatial Modulation of Rho GTPases during in Vitro Formation of Capillary Vascular Network: ADHERENS JUNCTIONS AND MYOSIN LIGHT CHAIN AS TARGETS OF Rac1 AND RhoA
J. Biol. Chem. 2003 278: -50713. First Published on September 12, 2003; doi:10.1074/jbc.M307234200 [Abstract] [Full Text] [PDF]

Changlu Liu, Elo Eriste, Steven Sutton, Jingcai Chen, Barbara Roland, Chester Kuei, Niven Farmer, Hans Jörnvall, Rannar Sillard, and Timothy W. Lovenberg: Identification of Relaxin-3/INSL7 as an Endogenous Ligand for the Orphan G-protein-coupled Receptor GPCR135
J. Biol. Chem. 2003 278: -50764. First Published on September 30, 2003; doi:10.1074/jbc.M308995200 [Abstract] [Full Text] [PDF]

Changlu Liu, Jingcai Chen, Steven Sutton, Barbara Roland, Chester Kuei, Niven Farmer, Rannar Sillard, and Timothy W. Lovenberg: Identification of Relaxin-3/INSL7 as a Ligand for GPCR142
J. Biol. Chem. 2003 278: -50770. First Published on September 30, 2003; doi:10.1074/jbc.M308996200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Melissa E. Hatley, Suseela Srinivasan, Kelly B. Reilly, David T. Bolick, and Catherine C. Hedrick: Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice. Vol. 278 (2003) 25369-25375
J. Biol. Chem. 2003 278: . [Full Text] [PDF]