Reflections:

Henry Lardy

Happily at Work
J. Biol. Chem. 2003 278: 3499-3509. First Published on December 18, 2002; doi:10.1074/jbc.X200003200 [Full Text] [PDF]  

Accelerated Publications:

Botond Bánfi, Robert A. Clark, Klaus Steger, and Karl-Heinz Krause

Two Novel Proteins Activate Superoxide Generation by the NADPH Oxidase NOX1
J. Biol. Chem. 2003 278: 3510-3513. First Published on December 6, 2002; doi:10.1074/jbc.C200613200 [Abstract] [Full Text] [PDF]  

DNA: Replication, Repair, and Recombination:

Martine Defais, Emilie Phez, and Neil P. Johnson

Kinetic Mechanism for the Formation of the Presynaptic Complex of the Bacterial Recombinase RecA
J. Biol. Chem. 2003 278: 3545-3551. First Published on November 26, 2002; doi:10.1074/jbc.M204341200 [Abstract] [Full Text] [PDF]  

Siyang Sun and Yousif Shamoo

Biochemical Characterization of Interactions between DNA Polymerase and Single-stranded DNA-binding Protein in Bacteriophage RB69
J. Biol. Chem. 2003 278: 3876-3881. First Published on November 27, 2002; doi:10.1074/jbc.M210497200 [Abstract] [Full Text] [PDF]  

Dimitry Bosoy, Yun Peng, I. Saira Mian, and Neal F. Lue

Conserved N-terminal Motifs of Telomerase Reverse Transcriptase Required for Ribonucleoprotein Assembly in Vivo
J. Biol. Chem. 2003 278: 3882-3890. First Published on November 27, 2002; doi:10.1074/jbc.M210645200 [Abstract] [Full Text] [PDF]  

Scott D. McCulloch, Liya Gu, and Guo-Min Li

Bi-directional Processing of DNA Loops by Mismatch Repair-dependent and -independent Pathways in Human Cells
J. Biol. Chem. 2003 278: 3891-3896. First Published on November 27, 2002; doi:10.1074/jbc.M210687200 [Abstract] [Full Text] [PDF]  

Huiyi Miao, Jennifer A. Seiler, and William C. Burhans

Regulation of Cellular and SV40 Virus Origins of Replication by Chk1-dependent Intrinsic and UVC Radiation-induced Checkpoints
J. Biol. Chem. 2003 278: 4295-4304. First Published on November 6, 2002; doi:10.1074/jbc.M204264200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Koji Ikeda, Noriaki Emoto, Masafumi Matsuo, and Mitsuhiro Yokoyama

Molecular Identification and Characterization of a Novel Nuclear Protein Whose Expression Is Up-regulated in Insulin-resistant Animals
J. Biol. Chem. 2003 278: 3514-3520. First Published on November 26, 2002; doi:10.1074/jbc.M204563200 [Abstract] [Full Text] [PDF]  

Tara A. Nevins, Zdena M. Harder, Robert G. Korneluk, and Martin Holík

Distinct Regulation of Internal Ribosome Entry Site-mediated Translation following Cellular Stress Is Mediated by Apoptotic Fragments of eIF4G Translation Initiation Factor Family Members eIF4GI and p97/DAP5/NAT1
J. Biol. Chem. 2003 278: 3572-3579. First Published on November 27, 2002; doi:10.1074/jbc.M206781200 [Abstract] [Full Text] [PDF]  

Cheol Kyu Hwang, Xiuli Wu, Guilin Wang, Chun Sung Kim, and Horace H. Loh

Mouse µ Opioid Receptor Distal Promoter Transcriptional Regulation by SOX Proteins
J. Biol. Chem. 2003 278: 3742-3750. First Published on November 22, 2002; doi:10.1074/jbc.M208780200 [Abstract] [Full Text] [PDF]  

Ping Cheng, Yuhong Yang, Lixin Wang, Qiyang He, and Yi Liu

WHITE COLLAR-1, a Multifunctional Neurospora Protein Involved in the Circadian Feedback Loops, Light Sensing, and Transcription Repression of wc-2
J. Biol. Chem. 2003 278: 3801-3808. First Published on November 25, 2002; doi:10.1074/jbc.M209592200 [Abstract] [Full Text] [PDF]  

Kristin Brevik Andersson, Elisabeth Kowenz-Leutz, Elen Margrethe Brendeford, Ann-Helen Herwig Tygsett, Achim Leutz, and Odd S. Gabrielsen

Phosphorylation-dependent Down-regulation of c-Myb DNA Binding Is Abrogated by a Point Mutation in the v-myb Oncogene
J. Biol. Chem. 2003 278: 3816-3824. First Published on November 26, 2002; doi:10.1074/jbc.M209404200 [Abstract] [Full Text] [PDF]  

Darius Balciunas, Magnus Hallberg, Stefan Björklund, and Hans Ronne

Functional Interactions within Yeast Mediator and Evidence of Differential Subunit Modifications
J. Biol. Chem. 2003 278: 3831-3839. First Published on December 4, 2002; doi:10.1074/jbc.M206946200 [Abstract] [Full Text] [PDF]  

François Fuks, Paul J. Hurd, Daniel Wolf, Xinsheng Nan, Adrian P. Bird, and Tony Kouzarides

The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation
J. Biol. Chem. 2003 278: 4035-4040. First Published on November 9, 2002; doi:10.1074/jbc.M210256200 [Abstract] [Full Text] [PDF]  

Catherine P. Kirschke and Liping Huang

ZnT7, a Novel Mammalian Zinc Transporter, Accumulates Zinc in the Golgi Apparatus
J. Biol. Chem. 2003 278: 4096-4102. First Published on November 21, 2002; doi:10.1074/jbc.M207644200 [Abstract] [Full Text] [PDF]  

Alberto Danielli, Fotis C. Kafatos, and Thanasis G. Loukeris

Cloning and Characterization of Four Anopheles gambiae Serpin Isoforms, Differentially Induced in the Midgut by Plasmodium berghei Invasion
J. Biol. Chem. 2003 278: 4184-4193. First Published on November 26, 2002; doi:10.1074/jbc.M208187200 [Abstract] [Full Text] [PDF]  

James J. Potter, Lynda Rennie-Tankersley, and Esteban Mezey

Endotoxin Enhances Liver Alcohol Dehydrogenase by Action through Upstream Stimulatory Factor but Not by Nuclear Factor-B
J. Biol. Chem. 2003 278: 4353-4357. First Published on November 25, 2002; doi:10.1074/jbc.M210097200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Max Nunziante, Sabine Gilch, and Hermann M. Schätzl

Essential Role of the Prion Protein N Terminus in Subcellular Trafficking and Half-life of Cellular Prion Protein
J. Biol. Chem. 2003 278: 3726-3734. First Published on November 12, 2002; doi:10.1074/jbc.M206313200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Héctor Villa, Ana R. Otero Marcos, Rosa M. Reguera, Rafael Balaña-Fouce, Carlos García-Estrada, Yolanda Pérez-Pertejo, Babu L. Tekwani, Peter J. Myler, Kenneth D. Stuart, Mary-Ann Bjornsti, and David Ordóñez

A Novel Active DNA Topoisomerase I in Leishmania donovani
J. Biol. Chem. 2003 278: 3521-3526. First Published on November 19, 2002; doi:10.1074/jbc.M203991200 [Abstract] [Full Text] [PDF]  

Tushar K. Beuria, Shyam Sundar Krishnakumar, Saurabh Sahar, Neera Singh, Kamlesh Gupta, Mallika Meshram, and Dulal Panda

Glutamate-induced Assembly of Bacterial Cell Division Protein FtsZ
J. Biol. Chem. 2003 278: 3735-3741. First Published on November 22, 2002; doi:10.1074/jbc.M205760200 [Abstract] [Full Text] [PDF]  

Olli H. Laitinen, Henri R. Nordlund, Vesa P. Hytönen, Sanna T. H. Uotila, Ari T. Marttila, Janne Savolainen, Kari J. Airenne, Oded Livnah, Edward A. Bayer, Meir Wilchek, and Markku S. Kulomaa

Rational Design of an Active Avidin Monomer
J. Biol. Chem. 2003 278: 4010-4014. First Published on November 27, 2002; doi:10.1074/jbc.M205844200 [Abstract] [Full Text] [PDF]  

Jeremiah Stitham, Aleksandar Stojanovic, Bethany L. Merenick, Kimberley A. O'Hara, and John Hwa

The Unique Ligand-binding Pocket for the Human Prostacyclin Receptor. SITE-DIRECTED MUTAGENESIS AND MOLECULAR MODELING
J. Biol. Chem. 2003 278: 4250-4257. First Published on November 21, 2002; doi:10.1074/jbc.M207420200 [Abstract] [Full Text] [PDF]  

Toshihiro Sato, Yoshimi Shimada, Naoko Nagasawa, Shigetada Nakanishi, and Hisato Jingami

Amino Acid Mutagenesis of the Ligand Binding Site and the Dimer Interface of the Metabotropic Glutamate Receptor 1. IDENTIFICATION OF CRUCIAL RESIDUES FOR SETTING THE ACTIVATED STATE
J. Biol. Chem. 2003 278: 4314-4321. First Published on November 19, 2002; doi:10.1074/jbc.M210278200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Haobo Jiang, Yang Wang, Xiao-Qiang Yu, and Michael R. Kanost

Prophenoloxidase-activating Proteinase-2 from Hemolymph of Manduca sexta. A BACTERIA-INDUCIBLE SERINE PROTEINASE CONTAINING TWO CLIP DOMAINS
J. Biol. Chem. 2003 278: 3552-3561. First Published on November 26, 2002; doi:10.1074/jbc.M205743200 [Abstract] [Full Text] [PDF]  

Shigenobu Kimura, Masanori Kawamura, and Takashi Iyanagi

Role of Thr⁶⁶ in Porcine NADH-cytochrome b₅ Reductase in Catalysis and Control of the Rate-limiting Step in Electron Transfer
J. Biol. Chem. 2003 278: 3580-3589. First Published on November 28, 2002; doi:10.1074/jbc.M209838200 [Abstract] [Full Text] [PDF]  

Changcheng Song, Qing Wang, and Chou-Chi H. Li

ATPase Activity of p97-Valosin-containing Protein (VCP). D2 MEDIATES THE MAJOR ENZYME ACTIVITY, AND D1 CONTRIBUTES TO THE HEAT-INDUCED ACTIVITY
J. Biol. Chem. 2003 278: 3648-3655. First Published on November 20, 2002; doi:10.1074/jbc.M208422200 [Abstract] [Full Text] [PDF]  

Guillermo Mariño, José A. Uría, Xose S. Puente, Víctor Quesada, Javier Bordallo, and Carlos López-Otín

Human Autophagins, a Family of Cysteine Proteinases Potentially Implicated in Cell Degradation by Autophagy
J. Biol. Chem. 2003 278: 3671-3678. First Published on November 21, 2002; doi:10.1074/jbc.M208247200 [Abstract] [Full Text] [PDF]  

Mireille Ferrand, Valérie Le Fourn, and Jean-Louis Franc

Increasing Diversity of Human Thyroperoxidase Generated by Alternative Splicing. CHARACTERIZATION BY MOLECULAR CLONING OF NEW TRANSCRIPTS WITH SINGLE- AND MULTISPLICED mRNAs
J. Biol. Chem. 2003 278: 3793-3800. First Published on November 25, 2002; doi:10.1074/jbc.M209513200 [Abstract] [Full Text] [PDF]  

Mathieu Lesort, Matthew Lee, Janusz Tucholski, and Gail V. W. Johnson

Cystamine Inhibits Caspase Activity. IMPLICATIONS FOR THE TREATMENT OF POLYGLUTAMINE DISORDERS
J. Biol. Chem. 2003 278: 3825-3830. First Published on November 27, 2002; doi:10.1074/jbc.M205812200 [Abstract] [Full Text] [PDF]  

Isabelle Bougie, Sébastien Charpentier, and Martin Bisaillon

Characterization of the Metal Ion Binding Properties of the Hepatitis C Virus RNA Polymerase
J. Biol. Chem. 2003 278: 3868-3875. First Published on November 27, 2002; doi:10.1074/jbc.M209785200 [Abstract] [Full Text] [PDF]  

Mark J. I. Paine, Lesley A. McLaughlin, Jack U. Flanagan, Carol A. Kemp, Michael J. Sutcliffe, Gordon C. K. Roberts, and C. Roland Wolf

Residues Glutamate 216 and Aspartate 301 Are Key Determinants of Substrate Specificity and Product Regioselectivity in Cytochrome P450 2D6
J. Biol. Chem. 2003 278: 4021-4027. First Published on November 22, 2002; doi:10.1074/jbc.M209519200 [Abstract] [Full Text] [PDF]  

Katrin Sichler, Erhard Kopetzki, Robert Huber, Wolfram Bode, Karl-Peter Hopfner, and Hans Brandstetter

Physiological fIXa Activation Involves a Cooperative Conformational Rearrangement of the 99-Loop
J. Biol. Chem. 2003 278: 4121-4126. First Published on November 19, 2002; doi:10.1074/jbc.M210722200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Mika Kurkela, J. Arturo García-Horsman, Leena Luukkanen, Saila Mörsky, Jyrki Taskinen, Marc Baumann, Risto Kostiainen, Jouni Hirvonen, and Moshe Finel

Expression and Characterization of Recombinant Human UDP-glucuronosyltransferases (UGTs). UGT1A9 IS MORE RESISTANT TO DETERGENT INHIBITION THAN THE OTHER UGTs AND WAS PURIFIED AS AN ACTIVE DIMERIC ENZYME
J. Biol. Chem. 2003 278: 3536-3544. First Published on November 14, 2002; doi:10.1074/jbc.M206136200 [Abstract] [Full Text] [PDF]  

Hideaki Maki, Katsumi Matsuura, Keizo Shimada, and Kenji V. P. Nagashima

Chimeric Photosynthetic Reaction Center Complex of Purple Bacteria Composed of the Core Subunits of Rubrivivax gelatinosus and the Cytochrome Subunit of Blastochloris viridis
J. Biol. Chem. 2003 278: 3921-3928. First Published on December 2, 2002; doi:10.1074/jbc.M209069200 [Abstract] [Full Text] [PDF]  

Carlo Colombo, Martin Haluzik, Jaime J. Cutson, Kelly R. Dietz, Bernice Marcus-Samuels, Charles Vinson, Oksana Gavrilova, and Marc L. Reitman

Opposite Effects of Background Genotype on Muscle and Liver Insulin Sensitivity of Lipoatrophic Mice. ROLE OF TRIGLYCERIDE CLEARANCE
J. Biol. Chem. 2003 278: 3992-3999. First Published on November 26, 2002; doi:10.1074/jbc.M207665200 [Abstract] [Full Text] [PDF]  

Anna Ghelli, Claudia Zanna, Anna Maria Porcelli, Anthony H. V. Schapira, Andrea Martinuzzi, Valerio Carelli, and Michela Rugolo

Leber's Hereditary Optic Neuropathy (LHON) Pathogenic Mutations Induce Mitochondrial-dependent Apoptotic Death in Transmitochondrial Cells Incubated with Galactose Medium
J. Biol. Chem. 2003 278: 4145-4150. First Published on November 21, 2002; doi:10.1074/jbc.M210285200 [Abstract] [Full Text] [PDF]  

Axel Niebisch and Michael Bott

Purification of a Cytochrome bc₁-aa₃ Supercomplex with Quinol Oxidase Activity from Corynebacterium glutamicum. IDENTIFICATION OF A FOURTH SUBUNIT OF CYTOCHROME aa₃ OXIDASE AND MUTATIONAL ANALYSIS OF DIHEME CYTOCHROME c₁
J. Biol. Chem. 2003 278: 4339-4346. First Published on November 20, 2002; doi:10.1074/jbc.M210499200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Bernd Kneidinger, Katie O'Riordan, Jianjun Li, Jean-Robert Brisson, Jean C. Lee, and Joseph S. Lam

Three Highly Conserved Proteins Catalyze the Conversion of UDP-N-acetyl-D-glucosamine to Precursors for the Biosynthesis of O Antigen in Pseudomonas aeruginosa O11 and Capsule in Staphylococcus aureus Type 5. IMPLICATIONS FOR THE UDP-N-ACETYL-L-FUCOSAMINE BIOSYNTHETIC PATHWAY
J. Biol. Chem. 2003 278: 3615-3627. First Published on December 2, 2002; doi:10.1074/jbc.M203867200 [Abstract] [Full Text] [PDF]  

Mariola Paciak, Otto Holst, Buko Lindner, Halina Mordarska, and Andrzej Gamian

Novel Bacterial Polar Lipids Containing Ether-linked Alkyl Chains, the Structures and Biological Properties of the Four Major Glycolipids from Propionibacterium propionicum PCM 2431 (ATCC 14157^T)
J. Biol. Chem. 2003 278: 3948-3956. First Published on November 8, 2002; doi:10.1074/jbc.M206013200 [Abstract] [Full Text] [PDF]  

Seshu K. Gudlavalleti and Lennart S. Forsberg

Structural Characterization of the Lipid A Component of Sinorhizobium sp. NGR234 Rough and Smooth Form Lipopolysaccharide. DEMONSTRATION THAT THE DISTAL AMIDE-LINKED ACYLOXYACYL RESIDUE CONTAINING THE LONG CHAIN FATTY ACID IS CONSERVED IN RHIZOBIUM AND SINORHIZOBIUM SP.
J. Biol. Chem. 2003 278: 3957-3968. First Published on November 26, 2002; doi:10.1074/jbc.M210491200 [Abstract] [Full Text] [PDF] Supplemental Data  

Alan S. Cross, Serhan Sakarya, Salahaldin Rifat, Thomas K. Held, Beth-Ellen Drysdale, Philippe A. Grange, Frederick J. Cassels, Lai-Xi Wang, Nicholas Stamatos, Ann Farese, Daniel Casey, Jan Powell, Apurba K. Bhattacharjee, Michael Kleinberg, and Simeon E. Goldblum

Recruitment of Murine Neutrophils in Vivo through Endogenous Sialidase Activity
J. Biol. Chem. 2003 278: 4112-4120. First Published on November 22, 2002; doi:10.1074/jbc.M207591200 [Abstract] [Full Text] [PDF]  

Sophia K. Khaldoyanidi, Vladislar V. Glinsky, Lyudmila Sikora, Anna B. Glinskii, Valerie V. Mossine, Thomas P. Quinn, Gennadi V. Glinsky, and P. Sriramarao

MDA-MB-435 Human Breast Carcinoma Cell Homo- and Heterotypic Adhesion under Flow Conditions Is Mediated in Part by Thomsen-Friedenreich Antigen-Galectin-3 Interactions
J. Biol. Chem. 2003 278: 4127-4134. First Published on November 15, 2002; doi:10.1074/jbc.M209590200 [Abstract] [Full Text] [PDF]  

Sylvain C. P. Eschenlauer and Antony P. Page

The Caenorhabditis elegans ERp60 Homolog Protein Disulfide Isomerase-3 Has Disulfide Isomerase and Transglutaminase-like Cross-linking Activity and Is Involved in the Maintenance of Body Morphology
J. Biol. Chem. 2003 278: 4227-4237. First Published on November 6, 2002; doi:10.1074/jbc.M210510200 [Abstract] [Full Text] [PDF]  

Maurizio Mongiat, Shawn M. Sweeney, James D. San Antonio, Jian Fu, and Renato V. Iozzo

Endorepellin, a Novel Inhibitor of Angiogenesis Derived from the C Terminus of Perlecan
J. Biol. Chem. 2003 278: 4238-4249. First Published on November 14, 2002; doi:10.1074/jbc.M210445200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

John D. Hearn, Robert L. Lester, and Robert C. Dickson

The Uracil Transporter Fur4p Associates with Lipid Rafts
J. Biol. Chem. 2003 278: 3679-3686. First Published on November 21, 2002; doi:10.1074/jbc.M209170200 [Abstract] [Full Text] [PDF]  

Gopal K. Marathe, Guy A. Zimmerman, and Thomas M. McIntyre

Platelet-activating Factor Acetylhydrolase, and Not Paraoxonase-1, Is the Oxidized Phospholipid Hydrolase of High Density Lipoprotein Particles
J. Biol. Chem. 2003 278: 3937-3947. First Published on December 3, 2002; doi:10.1074/jbc.M211126200 [Abstract] [Full Text] [PDF]  

Barbara Karten, Dennis E. Vance, Robert B. Campenot, and Jean E. Vance

Trafficking of Cholesterol from Cell Bodies to Distal Axons in Niemann Pick C1-deficient Neurons
J. Biol. Chem. 2003 278: 4168-4175. First Published on November 27, 2002; doi:10.1074/jbc.M205406200 [Abstract] [Full Text] [PDF]  

Satoshi Yasuda, Masahiro Nishijima, and Kentaro Hanada

Localization, Topology, and Function of the LCB1 Subunit of Serine Palmitoyltransferase in Mammalian Cells
J. Biol. Chem. 2003 278: 4176-4183. First Published on December 2, 2002; doi:10.1074/jbc.M209602200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Yue-xian Hou, John R. Riordan, and Xiu-bao Chang

ATP Binding, Not Hydrolysis, at the First Nucleotide-binding Domain of Multidrug Resistance-associated Protein MRP1 Enhances ADP·Vi Trapping at the Second Domain
J. Biol. Chem. 2003 278: 3599-3605. First Published on November 27, 2002; doi:10.1074/jbc.M210480200 [Abstract] [Full Text] [PDF]  

Jordi Benach, Yi-Te Chou, John J. Fak, Anna Itkin, Daita D. Nicolae, Paul C. Smith, Guenther Wittrock, Daniel L. Floyd, Cyrus M. Golsaz, Lila M. Gierasch, and John F. Hunt

Phospholipid-induced Monomerization and Signal-peptide-induced Oligomerization of SecA
J. Biol. Chem. 2003 278: 3628-3638. First Published on October 27, 2002; doi:10.1074/jbc.M205992200 [Abstract] [Full Text] [PDF]  

Baruch I. Kanner

Transmembrane Domain I of the -Aminobutyric Acid Transporter GAT-1 Plays a Crucial Role in the Transition between Cation Leak and Transport Modes
J. Biol. Chem. 2003 278: 3705-3712. First Published on November 21, 2002; doi:10.1074/jbc.M210525200 [Abstract] [Full Text] [PDF]  

Christopher G. Carlson, Antoni Barrientos, Alexander Tzagoloff, and D. Moira Glerum

COX16 Encodes a Novel Protein Required for the Assembly of Cytochrome Oxidase in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 3770-3775. First Published on November 22, 2002; doi:10.1074/jbc.M209893200 [Abstract] [Full Text] [PDF]  

Haruko Masumiya, Ruiwu Wang, Jing Zhang, Bailong Xiao, and S. R. Wayne Chen

Localization of the 12.6-kDa FK506-binding Protein (FKBP12.6) Binding Site to the NH₂-terminal Domain of the Cardiac Ca²⁺ Release Channel (Ryanodine Receptor)
J. Biol. Chem. 2003 278: 3786-3792. First Published on November 22, 2002; doi:10.1074/jbc.M210962200 [Abstract] [Full Text] [PDF]  

Amparo Haro, Marisela Vélez, Erik Goormaghtigh, Santiago Lago, Jesús Vázquez, David Andreu, and María Gasset

Reconstitution of Holin Activity with a Synthetic Peptide Containing the 1-32 Sequence Region of EJh, the EJ-1 Phage Holin
J. Biol. Chem. 2003 278: 3929-3936. First Published on December 2, 2002; doi:10.1074/jbc.M211334200 [Abstract] [Full Text] [PDF]  

Veedamali S. Subramanian, Jonathan S. Marchant, Ian Parker, and Hamid M. Said

Cell Biology of the Human Thiamine Transporter-1 (hTHTR1). INTRACELLULAR TRAFFICKING AND MEMBRANE TARGETING MECHANISMS
J. Biol. Chem. 2003 278: 3976-3984. First Published on November 25, 2002; doi:10.1074/jbc.M210717200 [Abstract] [Full Text] [PDF] Supplemental Data  

An-Qiang Sun, Rachita Salkar, Sachchidanand, Shuhua Xu, Lei Zeng, Ming-Ming Zhou, and Frederick J. Suchy

A 14-Amino Acid Sequence with a -Turn Structure Is Required for Apical Membrane Sorting of the Rat Ileal Bile Acid Transporter
J. Biol. Chem. 2003 278: 4000-4009. First Published on November 14, 2002; doi:10.1074/jbc.M207163200 [Abstract] [Full Text] [PDF]  

David J. Adams, Amanda B. Smith, Christina I. Schroeder, Takahiro Yasuda, and Richard J. Lewis

-Conotoxin CVID Inhibits a Pharmacologically Distinct Voltage-sensitive Calcium Channel Associated with Transmitter Release from Preganglionic Nerve Terminals
J. Biol. Chem. 2003 278: 4057-4062. First Published on November 18, 2002; doi:10.1074/jbc.M209969200 [Abstract] [Full Text] [PDF]  

Niels R. Bradshaw, N. Doane Chilcoat, John W. Verbsky, and Aaron P. Turkewitz

Proprotein Processing within Secretory Dense Core Granules of Tetrahymena thermophila
J. Biol. Chem. 2003 278: 4087-4095. First Published on November 14, 2002; doi:10.1074/jbc.M207236200 [Abstract] [Full Text] [PDF]  

Jan Modregger, Anne A. Schmidt, Brigitte Ritter, Wieland B. Huttner, and Markus Plomann

Characterization of Endophilin B1b, a Brain-specific Membrane-associated Lysophosphatidic Acid Acyl Transferase with Properties Distinct from Endophilin A1
J. Biol. Chem. 2003 278: 4160-4167. First Published on November 26, 2002; doi:10.1074/jbc.M208568200 [Abstract] [Full Text] [PDF]  

Michael R. Luke, Lars Kjer-Nielsen, Darren L. Brown, Jennifer L. Stow, and Paul A. Gleeson

GRIP Domain-mediated Targeting of Two New Coiled-coil Proteins, GCC88 and GCC185, to Subcompartments of the trans-Golgi Network
J. Biol. Chem. 2003 278: 4216-4226. First Published on November 20, 2002; doi:10.1074/jbc.M210387200 [Abstract] [Full Text] [PDF]  

Andrey Kosolapov and Carol Deutsch

Folding of the Voltage-gated K⁺ Channel T1 Recognition Domain
J. Biol. Chem. 2003 278: 4305-4313. First Published on November 12, 2002; doi:10.1074/jbc.M209422200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Silke Jung, Anja Mühle, Michael Schaefer, Rainer Strotmann, Günter Schultz, and Tim D. Plant

Lanthanides Potentiate TRPC5 Currents by an Action at Extracellular Sites Close to the Pore Mouth
J. Biol. Chem. 2003 278: 3562-3571. First Published on November 26, 2002; doi:10.1074/jbc.M211484200 [Abstract] [Full Text] [PDF]  

Louis Gendron, Jean-François Oligny, Marcel Daniel Payet, and Nicole Gallo-Payet

Cyclic AMP-independent Involvement of Rap1/B-Raf in the Angiotensin II AT₂ Receptor Signaling Pathway in NG108-15 Cells
J. Biol. Chem. 2003 278: 3606-3614. First Published on December 2, 2002; doi:10.1074/jbc.M202446200 [Abstract] [Full Text] [PDF]  

Christopher J. Nelsen, David G. Rickheim, Melissa M. Tucker, Linda K. Hansen, and Jeffrey H. Albrecht

Evidence That Cyclin D1 Mediates Both Growth and Proliferation Downstream of TOR in Hepatocytes
J. Biol. Chem. 2003 278: 3656-3663. First Published on November 20, 2002; doi:10.1074/jbc.M209374200 [Abstract] [Full Text] [PDF]  

Ryouhei Tsutsumi, Hideaki Higashi, Megumi Higuchi, Masato Okada, and Masanori Hatakeyama

Attenuation of Helicobacter pylori CagA·SHP-2 Signaling by Interaction between CagA and C-terminal Src Kinase
J. Biol. Chem. 2003 278: 3664-3670. First Published on November 21, 2002; doi:10.1074/jbc.M208155200 [Abstract] [Full Text] [PDF]  

Christopher W. Dawson, Giorgos Tramountanis, Aristides G. Eliopoulos, and Lawrence S. Young

Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) Activates the Phosphatidylinositol 3-Kinase/Akt Pathway to Promote Cell Survival and Induce Actin Filament Remodeling
J. Biol. Chem. 2003 278: 3694-3704. First Published on November 21, 2002; doi:10.1074/jbc.M209840200 [Abstract] [Full Text] [PDF]  

Shin-ichiro Miura, Jingli Zhang, John Boros, and Sadashiva S. Karnik

TM2-TM7 Interaction in Coupling Movement of Transmembrane Helices to Activation of the Angiotensin II Type-1 Receptor
J. Biol. Chem. 2003 278: 3720-3725. First Published on November 21, 2002; doi:10.1074/jbc.M211338200 [Abstract] [Full Text] [PDF]  

Susumu Itoh, Midory Thorikay, Marcin Kowanetz, Aristidis Moustakas, Fumiko Itoh, Carl-Henrik Heldin, and Peter ten Dijke

Elucidation of Smad Requirement in Transforming Growth Factor- Type I Receptor-induced Responses
J. Biol. Chem. 2003 278: 3751-3761. First Published on November 22, 2002; doi:10.1074/jbc.M208258200 [Abstract] [Full Text] [PDF]  

Andreas Hecht and Marc P. Stemmler

Identification of a Promoter-specific Transcriptional Activation Domain at the C Terminus of the Wnt Effector Protein T-cell Factor 4
J. Biol. Chem. 2003 278: 3776-3785. First Published on November 22, 2002; doi:10.1074/jbc.M210081200 [Abstract] [Full Text] [PDF]  

Nickolay Neznanov, Lubov Neznanova, Roman V. Kondratov, Ludmila Burdelya, Eugene S. Kandel, Donald M. O'Rourke, Axel Ullrich, and Andrei V. Gudkov

Dominant Negative Form of Signal-regulatory Protein- (SIRP/SHPS-1) Inhibits Tumor Necrosis Factor-mediated Apoptosis by Activation of NF-B
J. Biol. Chem. 2003 278: 3809-3815. First Published on November 24, 2002; doi:10.1074/jbc.M210698200 [Abstract] [Full Text] [PDF]  

Ida Rishal, Tal Keren-Raifman, Daniel Yakubovich, Tatiana Ivanina, Carmen W. Dessauer, Vladlen Z. Slepak, and Nathan Dascal

Na⁺ Promotes the Dissociation between G_GDP and G, Activating G Protein-gated K⁺ Channels
J. Biol. Chem. 2003 278: 3840-3845. First Published on December 17, 2002; doi:10.1074/jbc.C200605200 [Abstract] [Full Text] [PDF]  

Toshiaki Yujiri, Ryouhei Nawata, Toru Takahashi, Yutaka Sato, Yukio Tanizawa, Toshio Kitamura, and Yoshitomo Oka

MEK Kinase 1 Interacts with Focal Adhesion Kinase and Regulates Insulin Receptor Substrate-1 Expression
J. Biol. Chem. 2003 278: 3846-3851. First Published on November 27, 2002; doi:10.1074/jbc.M206087200 [Abstract] [Full Text] [PDF]  

Chengjun Li, Cristiana Iosef, Christina Y. H. Jia, Victor K. M. Han, and Shawn Shun-Cheng Li

Dual Functional Roles for the X-linked Lymphoproliferative Syndrome Gene Product SAP/SH2D1A in Signaling through the Signaling Lymphocyte Activation Molecule (SLAM) Family of Immune Receptors
J. Biol. Chem. 2003 278: 3852-3859. First Published on November 27, 2002; doi:10.1074/jbc.M206649200 [Abstract] [Full Text] [PDF]  

K. Vinod Vijayan, Yan Liu, Jing-Fei Dong, and Paul F. Bray

Enhanced Activation of Mitogen-activated Protein Kinase and Myosin Light Chain Kinase by the Pro³³ Polymorphism of Integrin ₃
J. Biol. Chem. 2003 278: 3860-3867. First Published on November 29, 2002; doi:10.1074/jbc.M208680200 [Abstract] [Full Text] [PDF]  

Manoj K. Barthwal, Pradeep Sathyanarayana, Chanakya N. Kundu, Basabi Rana, Anamika Pradeep, Chandan Sharma, James R. Woodgett, and Ajay Rana

Negative Regulation of Mixed Lineage Kinase 3 by Protein Kinase B/AKT Leads to Cell Survival
J. Biol. Chem. 2003 278: 3897-3902. First Published on November 27, 2002; doi:10.1074/jbc.M211598200 [Abstract] [Full Text] [PDF]  

Erica M. Hanson, Harold Dickensheets, Cheng-Kui Qu, Raymond P. Donnelly, and Achsah D. Keegan

Regulation of the Dephosphorylation of Stat6. PARTICIPATION OF TYR-713 IN THE INTERLEUKIN-4 RECEPTOR , THE TYROSINE PHOSPHATASE SHP-1, AND THE PROTEASOME
J. Biol. Chem. 2003 278: 3903-3911. First Published on November 28, 2002; doi:10.1074/jbc.M211747200 [Abstract] [Full Text] [PDF]  

Véronique Rousseau, Olivier Goupille, Nathalie Morin, and Jean-Vianney Barnier

A New Constitutively Active Brain PAK3 Isoform Displays Modified Specificities toward Rac and Cdc42 GTPases
J. Biol. Chem. 2003 278: 3912-3920. First Published on December 2, 2002; doi:10.1074/jbc.M207251200 [Abstract] [Full Text] [PDF]  

Sampsa Pikkarainen, Heikki Tokola, Risto Kerkelä, Theresa Majalahti-Palviainen, Olli Vuolteenaho, and Heikki Ruskoaho

Endothelin-1-specific Activation of B-type Natriuretic Peptide Gene via p38 Mitogen-activated Protein Kinase and Nuclear ETS Factors
J. Biol. Chem. 2003 278: 3969-3975. First Published on November 21, 2002; doi:10.1074/jbc.M205616200 [Abstract] [Full Text] [PDF]  

T. Alexander Key, Terry D. Foutz, Vsevolod V. Gurevich, Larry A. Sklar, and Eric R. Prossnitz

N-Formyl Peptide Receptor Phosphorylation Domains Differentially Regulate Arrestin and Agonist Affinity
J. Biol. Chem. 2003 278: 4041-4047. First Published on November 6, 2002; doi:10.1074/jbc.M204687200 [Abstract] [Full Text] [PDF]  

Peng Sun, Hironobu Yamamoto, Shiro Suetsugu, Hiroaki Miki, Tadaomi Takenawa, and Takeshi Endo

Small GTPase Rah/Rab34 Is Associated with Membrane Ruffles and Macropinosomes and Promotes Macropinosome Formation
J. Biol. Chem. 2003 278: 4063-4071. First Published on November 21, 2002; doi:10.1074/jbc.M208699200 [Abstract] [Full Text] [PDF]  

Niklas Rye Jørgensen, Stefan Cuoni Teilmann, Zanne Henriksen, Roberto Civitelli, Ole Helmer Sørensen, and Thomas H. Steinberg

Activation of L-type Calcium Channels Is Required for Gap Junction-mediated Intercellular Calcium Signaling in Osteoblastic Cells
J. Biol. Chem. 2003 278: 4082-4086. First Published on November 22, 2002; doi:10.1074/jbc.M205880200 [Abstract] [Full Text] [PDF]  

Sun Young Moon, Heesuk Zang, and Yi Zheng

Characterization of a Brain-specific Rho GTPase-activating Protein, p200RhoGAP
J. Biol. Chem. 2003 278: 4151-4159. First Published on November 25, 2002; doi:10.1074/jbc.M207789200 [Abstract] [Full Text] [PDF]  

Mutay Aslan, Thomas M. Ryan, Tim M. Townes, Lori Coward, Marion C. Kirk, Stephen Barnes, C. Bruce Alexander, Steven S. Rosenfeld, and Bruce A. Freeman

Nitric Oxide-dependent Generation of Reactive Species in Sickle Cell Disease. ACTIN TYROSINE NITRATION INDUCES DEFECTIVE CYTOSKELETAL POLYMERIZATION
J. Biol. Chem. 2003 278: 4194-4204. First Published on October 24, 2002; doi:10.1074/jbc.M208916200 [Abstract] [Full Text] [PDF]  

Wei-Qin Zhao, Gina H. Chen, Hui Chen, Alessia Pascale, Lakshmi Ravindranath, Michael J. Quon, and Daniel L. Alkon

Secretion of Annexin II via Activation of Insulin Receptor and Insulin-like Growth Factor Receptor
J. Biol. Chem. 2003 278: 4205-4215. First Published on November 12, 2002; doi:10.1074/jbc.M210545200 [Abstract] [Full Text] [PDF]  

J. David Spafford, David W. Munno, Pim van Nierop, Zhong-Ping Feng, Scott E. Jarvis, Warren J. Gallin, August B. Smit, Gerald W. Zamponi, and Naweed I. Syed

Calcium Channel Structural Determinants of Synaptic Transmission between Identified Invertebrate Neurons
J. Biol. Chem. 2003 278: 4258-4267. First Published on November 27, 2002; doi:10.1074/jbc.M211076200 [Abstract] [Full Text] [PDF]  

Junya Masumoto, Weibin Zhou, Felicia F. Chen, Fengyun Su, John Y. Kuwada, Eiko Hidaka, Tsutomu Katsuyama, Junji Sagara, Shun'ichiro Taniguchi, Phuong Ngo-Hazelett, John H. Postlethwait, Gabriel Núñez, and Naohiro Inohara

Caspy, a Zebrafish Caspase, Activated by ASC Oligomerization Is Required for Pharyngeal Arch Development
J. Biol. Chem. 2003 278: 4268-4276. First Published on December 2, 2002; doi:10.1074/jbc.M203944200 [Abstract] [Full Text] [PDF]  

Laurence Braun, Thierry Christophe, and François Boulay

Phosphorylation of Key Serine Residues Is Required for Internalization of the Complement 5a (C5a) Anaphylatoxin Receptor via a -Arrestin, Dynamin, and Clathrin-dependent Pathway
J. Biol. Chem. 2003 278: 4277-4285. First Published on December 2, 2002; doi:10.1074/jbc.M210120200 [Abstract] [Full Text] [PDF]  

Adele Affaitati, Luca Cardone, Tiziana de Cristofaro, Annalisa Carlucci, Michael D. Ginsberg, Stelio Varrone, Max E. Gottesman, Enrico V. Avvedimento, and Antonio Feliciello

Essential Role of A-kinase Anchor Protein 121 for cAMP Signaling to Mitochondria
J. Biol. Chem. 2003 278: 4286-4294. First Published on November 8, 2002; doi:10.1074/jbc.M209941200 [Abstract] [Full Text] [PDF]  

Zhigang Li and David B. Sacks

Elucidation of the Interaction of Calmodulin with the IQ Motifs of IQGAP1
J. Biol. Chem. 2003 278: 4347-4352. First Published on November 20, 2002; doi:10.1074/jbc.M208579200 [Abstract] [Full Text] [PDF]  

Donna E. Muscarella and Stephen E. Bloom

Cross-linking of Surface IgM in the Burkitt's Lymphoma Cell Line ST486 Provides Protection against Arsenite- and Stress-induced Apoptosis That Is Mediated by ERK and Phosphoinositide 3-Kinase Signaling Pathways
J. Biol. Chem. 2003 278: 4358-4367. First Published on December 2, 2002; doi:10.1074/jbc.M208779200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Andrew T. Mackey and Susan P. Gilbert

The ATPase Cross-bridge Cycle of the Kar3 Motor Domain. IMPLICATIONS FOR SINGLE HEAD MOTILITY
J. Biol. Chem. 2003 278: 3527-3535. First Published on November 24, 2002; doi:10.1074/jbc.M206219200 [Abstract] [Full Text] [PDF]  

Judith Stegmüller, Hauke Werner, Klaus-Armin Nave, and Jacqueline Trotter

The Proteoglycan NG2 Is Complexed with -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors by the PDZ Glutamate Receptor Interaction Protein (GRIP) in Glial Progenitor Cells. IMPLICATIONS FOR GLIAL-NEURONAL SIGNALING
J. Biol. Chem. 2003 278: 3590-3598. First Published on November 27, 2002; doi:10.1074/jbc.M210010200 [Abstract] [Full Text] [PDF]  

Daniela Palmieri, Silvia Poggi, Valentina Ulivi, GianLuigi Casartelli, and Paola Manduca

Pro-collagen I COOH-terminal Trimer Induces Directional Migration and Metalloproteinases in Breast Cancer Cells
J. Biol. Chem. 2003 278: 3639-3647. First Published on November 18, 2002; doi:10.1074/jbc.M207483200 [Abstract] [Full Text] [PDF]  

Bao-yan Zhang, Ming Liu, and Peter Arvan

Behavior in the Eukaryotic Secretory Pathway of Insulin-containing Fusion Proteins and Single-chain Insulins Bearing Various B-chain Mutations
J. Biol. Chem. 2003 278: 3687-3693. First Published on November 21, 2002; doi:10.1074/jbc.M209474200 [Abstract] [Full Text] [PDF]  

Wu Xiang Liao, R. Kelly Moore, Fumio Otsuka, and Shunichi Shimasaki

Effect of Intracellular Interactions on the Processing and Secretion of Bone Morphogenetic Protein-15 (BMP-15) and Growth and Differentiation Factor-9. IMPLICATION OF THE ABERRANT OVARIAN PHENOTYPE OF BMP-15 MUTANT SHEEP
J. Biol. Chem. 2003 278: 3713-3719. First Published on November 21, 2002; doi:10.1074/jbc.M210598200 [Abstract] [Full Text] [PDF]  

Wei Wang, Jinping Xu, and Thorsten Kirsch

Annexin-mediated Ca²⁺ Influx Regulates Growth Plate Chondrocyte Maturation and Apoptosis
J. Biol. Chem. 2003 278: 3762-3769. First Published on November 22, 2002; doi:10.1074/jbc.M208868200 [Abstract] [Full Text] [PDF]  

Aikaterini Kontrogianni-Konstantopoulos and Robert J. Bloch

The Hydrophilic Domain of Small Ankyrin-1 Interacts with the Two N-terminal Immunoglobulin Domains of Titin
J. Biol. Chem. 2003 278: 3985-3991. First Published on November 19, 2002; doi:10.1074/jbc.M209012200 [Abstract] [Full Text] [PDF]  

Thomas J. Hawke, Nan Jiang, and Daniel J. Garry

Absence of p21^CIP Rescues Myogenic Progenitor Cell Proliferative and Regenerative Capacity in Foxk1 Null Mice
J. Biol. Chem. 2003 278: 4015-4020. First Published on November 21, 2002; doi:10.1074/jbc.M209200200 [Abstract] [Full Text] [PDF]  

Michael R. Olson, Christopher L. Holley, Soon Ji Yoo, Jun R. Huh, Bruce A. Hay, and Sally Kornbluth

Reaper Is Regulated by IAP-mediated Ubiquitination
J. Biol. Chem. 2003 278: 4028-4034. First Published on November 20, 2002; doi:10.1074/jbc.M209734200 [Abstract] [Full Text] [PDF]  

Songbai Zhang, Akihiro Mizutani, Chihiro Hisatsune, Takayasu Higo, Hiroko Bannai, Tomohiro Nakayama, Mitsuharu Hattori, and Katsuhiko Mikoshiba

Protein 4.1N Is Required for Translocation of Inositol 1,4,5-Trisphosphate Receptor Type 1 to the Basolateral Membrane Domain in Polarized Madin-Darby Canine Kidney Cells
J. Biol. Chem. 2003 278: 4048-4056. First Published on November 19, 2002; doi:10.1074/jbc.M209960200 [Abstract] [Full Text] [PDF] Supplemental Data  

Philipp Milkereit, Daniela Strauss, Jochen Bassler, Olivier Gadal, Holger Kühn, Sylvia Schütz, Nicole Gas, Johannes Lechner, Ed Hurt, and Herbert Tschochner

A Noc Complex Specifically Involved in the Formation and Nuclear Export of Ribosomal 40 S Subunits
J. Biol. Chem. 2003 278: 4072-4081. First Published on November 20, 2002; doi:10.1074/jbc.M208898200 [Abstract] [Full Text] [PDF]  

Masanori Asada, Kenji Irie, Koji Morimoto, Akio Yamada, Wataru Ikeda, Masakazu Takeuchi, and Yoshimi Takai

ADIP, a Novel Afadin- and -Actinin-Binding Protein Localized at Cell-Cell Adherens Junctions
J. Biol. Chem. 2003 278: 4103-4111. First Published on November 21, 2002; doi:10.1074/jbc.M209832200 [Abstract] [Full Text] [PDF]  

Jessy Deshane, Craig C. Garner, and Harald Sontheimer

Chlorotoxin Inhibits Glioma Cell Invasion via Matrix Metalloproteinase-2
J. Biol. Chem. 2003 278: 4135-4144. First Published on November 25, 2002; doi:10.1074/jbc.M205662200 [Abstract] [Full Text] [PDF]  

Ying-Zhi Xu, Yun Ji, Birgit Zipser, John Jellies, Kristen M. Johansen, and Jørgen Johansen

Proteolytic Cleavage of the Ectodomain of the L1 CAM Family Member Tractin
J. Biol. Chem. 2003 278: 4322-4330. First Published on November 21, 2002; doi:10.1074/jbc.M210775200 [Abstract] [Full Text] [PDF]  

Marie Granboulan, Danielle Lankar, Graça Raposo, Christian Bonnerot, and Claire Hivroz

Phosphoinositide 3-Kinase Activation by Ig Controls de Novo Formation of an Antigen-processing Compartment
J. Biol. Chem. 2003 278: 4331-4338. First Published on November 28, 2002; doi:10.1074/jbc.M209885200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Hiroshi Tokumitsu, Hiroyuki Inuzuka, Yumi Ishikawa, Masahiko Ikeda, Ikutaro Saji, and Ryoji Kobayashi

STO-609, a specific inhibitor of the Ca²⁺/calmodulin-dependent protein kinase kinase.
J. Biol. Chem. 2003 278: 4368. [Full Text] [PDF]  

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