Minireviews:

Akira Katsumi, A. Wayne Orr, Eleni Tzima, and Martin Alexander Schwartz

Integrins in Mechanotransduction
J. Biol. Chem. 2004 279: 12001-12004. First Published on February 11, 2004; doi:10.1074/jbc.R300038200 [Abstract] [Full Text] [PDF]  

Accelerated Publications:

Ulrika Andersson, Karin Filipsson, Caroline R. Abbott, Angela Woods, Kirsty Smith, Stephen R. Bloom, David Carling, and Caroline J. Small

AMP-activated Protein Kinase Plays a Role in the Control of Food Intake
J. Biol. Chem. 2004 279: 12005-12008. First Published on January 23, 2004; doi:10.1074/jbc.C300557200 [Abstract] [Full Text] [PDF]  

DNA: Replication, Repair, and Recombination:

Charles E. Jones, Timothy C. Mueser, and Nancy G. Nossal

Bacteriophage T4 32 Protein Is Required for Helicase-dependent Leading Strand Synthesis When the Helicase Is Loaded by the T4 59 Helicase-loading Protein
J. Biol. Chem. 2004 279: 12067-12075. First Published on January 17, 2004; doi:10.1074/jbc.M313840200 [Abstract] [Full Text] [PDF]  

Mi Ran Kang, Mark T. Muller, and In Kwon Chung

Telomeric DNA Damage by Topoisomerase I: A POSSIBLE MECHANISM FOR CELL KILLING BY CAMPTOTHECIN
J. Biol. Chem. 2004 279: 12535-12541. First Published on January 16, 2004; doi:10.1074/jbc.M309779200 [Abstract] [Full Text] [PDF]  

Chian Kwon and In Kwon Chung

Interaction of an Arabidopsis RNA-binding Protein with Plant Single-stranded Telomeric DNA Modulates Telomerase Activity
J. Biol. Chem. 2004 279: 12812-12818. First Published on December 31, 2003; doi:10.1074/jbc.M312011200 [Abstract] [Full Text] [PDF]  

Diego Loayza, Heather Parsons, Jill Donigian, Kristina Hoke, and Titia de Lange

DNA Binding Features of Human POT1: A NONAMER 5'-TAGGGTTAG-3' MINIMAL BINDING SITE, SEQUENCE SPECIFICITY, AND INTERNAL BINDING TO MULTIMERIC SITES
J. Biol. Chem. 2004 279: 13241-13248. First Published on January 7, 2004; doi:10.1074/jbc.M312309200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Nicholas W. Bateman, Dongfeng Tan, Richard G. Pestell, Jennifer D. Black, and Adrian R. Black

Intestinal Tumor Progression Is Associated with Altered Function of KLF5
J. Biol. Chem. 2004 279: 12093-12101. First Published on January 15, 2004; doi:10.1074/jbc.M311532200 [Abstract] [Full Text] [PDF]  

Craig E. Grossman, Yueming Qian, Katalin Banki, and Andras Perl

ZNF143 Mediates Basal and Tissue-specific Expression of Human Transaldolase
J. Biol. Chem. 2004 279: 12190-12205. First Published on December 31, 2003; doi:10.1074/jbc.M307039200 [Abstract] [Full Text] [PDF]  

Jianlin Chu and Emery H. Bresnick

Evidence That C Promoter-binding Factor 1 Binding Is Required for Notch-1-mediated Repression of Activator Protein-1
J. Biol. Chem. 2004 279: 12337-12345. First Published on November 26, 2003; doi:10.1074/jbc.M311510200 [Abstract] [Full Text] [PDF]  

Li Zhong, Keyun Qing, Yue Si, Linyuan Chen, Mengqun Tan, and Arun Srivastava

Heat-shock Treatment-mediated Increase in Transduction by Recombinant Adeno-associated Virus 2 Vectors Is Independent of the Cellular Heat-shock Protein 90
J. Biol. Chem. 2004 279: 12714-12723. First Published on January 7, 2004; doi:10.1074/jbc.M310548200 [Abstract] [Full Text] [PDF]  

Courtney Brown, John Gaspar, Allison Pettit, Rebecca Lee, Xuesong Gu, Hong Wang, Cathy Manning, Carole Voland, Steven R. Goldring, Mary B. Goldring, Towia A. Libermann, Ellen M. Gravallese, and Peter Oettgen

ESE-1 Is a Novel Transcriptional Mediator of Angiopoietin-1 Expression in the Setting of Inflammation
J. Biol. Chem. 2004 279: 12794-12803. First Published on January 8, 2004; doi:10.1074/jbc.M308593200 [Abstract] [Full Text] [PDF]  

Dexue Fu, Minae Kobayashi, and Li Lin

A p105-based Inhibitor Broadly Represses NF-B Activities
J. Biol. Chem. 2004 279: 12819-12826. First Published on January 1, 2004; doi:10.1074/jbc.M312572200 [Abstract] [Full Text] [PDF]  

Hiroaki Chiba, Hideo Michibata, Koji Wakimoto, Mariko Seishima, Satoshi Kawasaki, Kousaku Okubo, Hiroshi Mitsui, Hideshi Torii, and Yuji Imai

Cloning of a Gene for a Novel Epithelium-specific Cytosolic Phospholipase A₂, cPLA₂, Induced in Psoriatic Skin
J. Biol. Chem. 2004 279: 12890-12897. First Published on January 6, 2004; doi:10.1074/jbc.M305801200 [Abstract] [Full Text] [PDF]  

RNA: Structure, Metabolism, and Catalysis:

Masako Nomaguchi, Tadahisa Teramoto, Li Yu, Lewis Markoff, and R. Padmanabhan

Requirements for West Nile Virus (–)- and (+)-Strand Subgenomic RNA Synthesis in Vitro by the Viral RNA-dependent RNA Polymerase Expressed in Escherichia coli
J. Biol. Chem. 2004 279: 12141-12151. First Published on December 29, 2003; doi:10.1074/jbc.M310839200 [Abstract] [Full Text] [PDF] Supplemental Data  

Yan Yang, Rene Rijnbrand, Stanley Watowich, and Stanley M. Lemon

Genetic Evidence for an Interaction between a Picornaviral cis-Acting RNA Replication Element and 3CD Protein
J. Biol. Chem. 2004 279: 12659-12667. First Published on January 7, 2004; doi:10.1074/jbc.M312992200 [Abstract] [Full Text] [PDF]  

Jin-Yu Lu and Robert J. Schneider

Tissue Distribution of AU-rich mRNA-binding Proteins Involved in Regulation of mRNA Decay
J. Biol. Chem. 2004 279: 12974-12979. First Published on January 7, 2004; doi:10.1074/jbc.M310433200 [Abstract] [Full Text] [PDF]  

Natalie M. Sayer, Matthew Cubin, Alexandre Rhie, Marc Bullock, Abdessamad Tahiri-Alaoui, and William James

Structural Determinants of Conformationally Selective, Prion-binding Aptamers
J. Biol. Chem. 2004 279: 13102-13109. First Published on January 7, 2004; doi:10.1074/jbc.M310928200 [Abstract] [Full Text] [PDF] Supplemental Data  

Tsutomu Fujimura and Rosa Esteban

Bipartite 3'-Cis-acting Signal for Replication in Yeast 23 S RNA Virus and Its Repair
J. Biol. Chem. 2004 279: 13215-13223. First Published on January 13, 2004; doi:10.1074/jbc.M313797200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Hisashi Masuyama and Yuji Hiramatsu

Involvement of Suppressor for Gal 1 in the Ubiquitin/Proteasome-mediated Degradation of Estrogen Receptors
J. Biol. Chem. 2004 279: 12020-12026. First Published on December 30, 2003; doi:10.1074/jbc.M312762200 [Abstract] [Full Text] [PDF]  

Peter J. Lenting, Erik Westein, Virginie Terraube, Anne-Sophie Ribba, Eric G. Huizinga, Dominique Meyer, Philip G. de Groot, and Cécile V. Denis

An Experimental Model to Study the in Vivo Survival of von Willebrand Factor: BASIC ASPECTS AND APPLICATION TO THE R1205H MUTATION
J. Biol. Chem. 2004 279: 12102-12109. First Published on November 12, 2003; doi:10.1074/jbc.M310436200 [Abstract] [Full Text] [PDF]  

Gareth J. Browne, Stephen G. Finn, and Christopher G. Proud

Stimulation of the AMP-activated Protein Kinase Leads to Activation of Eukaryotic Elongation Factor 2 Kinase and to Its Phosphorylation at a Novel Site, Serine 398
J. Biol. Chem. 2004 279: 12220-12231. First Published on January 5, 2004; doi:10.1074/jbc.M309773200 [Abstract] [Full Text] [PDF]  

Robert Eichler, Oliver Lenz, Thomas Strecker, Markus Eickmann, Hans-Dieter Klenk, and Wolfgang Garten

Lassa Virus Glycoprotein Signal Peptide Displays a Novel Topology with an Extended Endoplasmic Reticulum Luminal Region
J. Biol. Chem. 2004 279: 12293-12299. First Published on January 6, 2004; doi:10.1074/jbc.M312975200 [Abstract] [Full Text] [PDF]  

Hirofumi Akari, Mikako Fujita, Sandra Kao, Mohammad A. Khan, Miranda Shehu-Xhilaga, Akio Adachi, and Klaus Strebel

High Level Expression of Human Immunodeficiency Virus Type-1 Vif Inhibits Viral Infectivity by Modulating Proteolytic Processing of the Gag Precursor at the p2/Nucleocapsid Processing Site
J. Biol. Chem. 2004 279: 12355-12362. First Published on January 13, 2004; doi:10.1074/jbc.M312426200 [Abstract] [Full Text] [PDF]  

Azmi Yerlikaya and Bruce A. Stanley

S-Adenosylmethionine Decarboxylase Degradation by the 26 S Proteasome Is Accelerated by Substrate-mediated Transamination
J. Biol. Chem. 2004 279: 12469-12478. First Published on January 12, 2004; doi:10.1074/jbc.M312625200 [Abstract] [Full Text] [PDF]  

Benjamin P. Fairfax, Julie A. Pitcher, Mark G. H. Scott, Andrew R. Calver, Menelas N. Pangalos, Stephen J. Moss, and Andrés Couve

Phosphorylation and Chronic Agonist Treatment Atypically Modulate GABA_B Receptor Cell Surface Stability
J. Biol. Chem. 2004 279: 12565-12573. First Published on January 5, 2004; doi:10.1074/jbc.M311389200 [Abstract] [Full Text] [PDF]  

Shicheng Yang, Yoon Shin Cho, Vargheese M. Chennathukuzhi, Lara A. Underkoffler, Kathleen Loomes, and Norman B. Hecht

Translin-associated Factor X Is Post-transcriptionally Regulated by Its Partner Protein TB-RBP, and Both Are Essential for Normal Cell Proliferation
J. Biol. Chem. 2004 279: 12605-12614. First Published on January 7, 2004; doi:10.1074/jbc.M313133200 [Abstract] [Full Text] [PDF]  

Peter Wujek, Elizabeth Kida, Marius Walus, Krystyna E. Wisniewski, and Adam A. Golabek

N-Glycosylation Is Crucial for Folding, Trafficking, and Stability of Human Tripeptidyl-peptidase I
J. Biol. Chem. 2004 279: 12827-12839. First Published on December 31, 2003; doi:10.1074/jbc.M313173200 [Abstract] [Full Text] [PDF]  

Evo Lindersson, Rasmus Beedholm, Peter Højrup, Torben Moos, WeiPing Gai, Klavs B. Hendil, and Poul H. Jensen

Proteasomal Inhibition by -Synuclein Filaments and Oligomers
J. Biol. Chem. 2004 279: 12924-12934. First Published on January 7, 2004; doi:10.1074/jbc.M306390200 [Abstract] [Full Text] [PDF]  

Yannick Goumon, Tommaso Angelone, Françoise Schoentgen, Sylvette Chasserot-Golaz, Bjorg Almas, Miriam M. Fukami, Keith Langley, Ingeborg D. Welters, Bruno Tota, Dominique Aunis, and Marie-Hélène Metz-Boutigue

The Hippocampal Cholinergic Neurostimulating Peptide, the N-terminal Fragment of the Secreted Phosphatidylethanolamine-binding Protein, Possesses a New Biological Activity on Cardiac Physiology
J. Biol. Chem. 2004 279: 13054-13064. First Published on January 14, 2004; doi:10.1074/jbc.M308533200 [Abstract] [Full Text] [PDF]  

Joungil Choi, Allan I. Levey, Susan T. Weintraub, Howard D. Rees, Marla Gearing, Lih-Shen Chin, and Lian Li

Oxidative Modifications and Down-regulation of Ubiquitin Carboxyl-terminal Hydrolase L1 Associated with Idiopathic Parkinson's and Alzheimer's Diseases
J. Biol. Chem. 2004 279: 13256-13264. First Published on January 13, 2004; doi:10.1074/jbc.M314124200 [Abstract] [Full Text] [PDF]  

Genomics, Proteomics, and Bioinformatics:

Ángel Zaballos, Ricardo Villares, Juan Pablo Albar, Carlos Martínez-A, and Gabriel Márquez

Identification on Mouse Chromosome 8 of New -Defensin Genes with Regionally Specific Expression in the Male Reproductive Organ
J. Biol. Chem. 2004 279: 12421-12426. First Published on January 12, 2004; doi:10.1074/jbc.M307697200 [Abstract] [Full Text] [PDF]  

Xueqiao Liu and Peter De Wulf

Probing the ArcA-P Modulon of Escherichia coli by Whole Genome Transcriptional Analysis and Sequence Recognition Profiling
J. Biol. Chem. 2004 279: 12588-12597. First Published on January 7, 2004; doi:10.1074/jbc.M313454200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Hiroaki Matsuo, Eishin Morita, Arthur Sydney Tatham, Kenichi Morimoto, Tatsuya Horikawa, Hiroyuki Osuna, Zenro Ikezawa, Sakae Kaneko, Kunie Kohno, and Satoshi Dekio

Identification of the IgE-binding Epitope in -5 Gliadin, a Major Allergen in Wheat-dependent Exercise-induced Anaphylaxis
J. Biol. Chem. 2004 279: 12135-12140. First Published on December 29, 2003; doi:10.1074/jbc.M311340200 [Abstract] [Full Text] [PDF]  

Janelle D. Green, Claire Goldsbury, Joerg Kistler, Garth J. S. Cooper, and Ueli Aebi

Human Amylin Oligomer Growth and Fibril Elongation Define Two Distinct Phases in Amyloid Formation
J. Biol. Chem. 2004 279: 12206-12212. First Published on January 1, 2004; doi:10.1074/jbc.M312452200 [Abstract] [Full Text] [PDF]  

Antony J. Davis, Matthew A. Perugini, Brian J. Smith, James D. Stewart, Thomas Ilg, Anthony N. Hodder, and Emanuela Handman

Properties of GDP-mannose Pyrophosphorylase, a Critical Enzyme and Drug Target in Leishmania mexicana
J. Biol. Chem. 2004 279: 12462-12468. First Published on January 12, 2004; doi:10.1074/jbc.M312365200 [Abstract] [Full Text] [PDF]  

Hironao Wakabayashi, Jan Freas, Qian Zhou, and Philip J. Fay

Residues 110–126 in the A1 Domain of Factor VIII Contain a Ca²⁺ Binding Site Required for Cofactor Activity
J. Biol. Chem. 2004 279: 12677-12684. First Published on January 13, 2004; doi:10.1074/jbc.M311042200 [Abstract] [Full Text] [PDF]  

Robert H. H. van den Heuvel, Adrie H. Westphal, Albert J. R. Heck, Martin A. Walsh, Stefano Rovida, Willem J. H. van Berkel, and Andrea Mattevi

Structural Studies on Flavin Reductase PheA2 Reveal Binding of NAD in an Unusual Folded Conformation and Support Novel Mechanism of Action
J. Biol. Chem. 2004 279: 12860-12867. First Published on December 31, 2003; doi:10.1074/jbc.M313765200 [Abstract] [Full Text] [PDF]  

Annie Hiniker and James C. A. Bardwell

In Vivo Substrate Specificity of Periplasmic Disulfide Oxidoreductases
J. Biol. Chem. 2004 279: 12967-12973. First Published on January 15, 2004; doi:10.1074/jbc.M311391200 [Abstract] [Full Text] [PDF]  

Maura V. Prates, Maurício L. Sforça, Wiliam C. B. Regis, José R. S. A. Leite, Luciano P. Silva, Thelma A. Pertinhez, Antônio L. T. Araújo, Ricardo B. Azevedo, Alberto Spisni, and Carlos Bloch, Jr.

The NMR-derived Solution Structure of a New Cationic Antimicrobial Peptide from the Skin Secretion of the Anuran Hyla punctata
J. Biol. Chem. 2004 279: 13018-13026. First Published on January 8, 2004; doi:10.1074/jbc.M310838200 [Abstract] [Full Text] [PDF]  

Qing Huai, Yudong Liu, Sharron H. Francis, Jackie D. Corbin, and Hengming Ke

Crystal Structures of Phosphodiesterases 4 and 5 in Complex with Inhibitor 3-Isobutyl-1-methylxanthine Suggest a Conformation Determinant of Inhibitor Selectivity
J. Biol. Chem. 2004 279: 13095-13101. First Published on December 10, 2003; doi:10.1074/jbc.M311556200 [Abstract] [Full Text] [PDF]  

Gerlind Sulzenbacher, Christophe Bignon, Takeshi Nishimura, Chris A. Tarling, Stephen G. Withers, Bernard Henrissat, and Yves Bourne

Crystal Structure of Thermotoga maritima -L-Fucosidase: INSIGHTS INTO THE CATALYTIC MECHANISM AND THE MOLECULAR BASIS FOR FUCOSIDOSIS
J. Biol. Chem. 2004 279: 13119-13128. First Published on January 8, 2004; doi:10.1074/jbc.M313783200 [Abstract] [Full Text] [PDF]  

Farhad Forouhar, Insun Lee, Jordi Benach, Kaushal Kulkarni, Rong Xiao, Thomas B. Acton, Gaetano T. Montelione, and Liang Tong

A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK)
J. Biol. Chem. 2004 279: 13148-13155. First Published on January 12, 2004; doi:10.1074/jbc.M313580200 [Abstract] [Full Text] [PDF]  

Takeshi Maeda, Makoto Inoue, Seizo Koshiba, Takashi Yabuki, Masaaki Aoki, Emi Nunokawa, Eiko Seki, Takayoshi Matsuda, Yoko Motoda, Atsuo Kobayashi, Fumiko Hiroyasu, Mikako Shirouzu, Takaho Terada, Nobuhiro Hayami, Yoshiko Ishizuka, Naoko Shinya, Ayako Tatsuguchi, Mayumi Yoshida, Hiroshi Hirota, Yo Matsuo, Kazutoshi Tani, Takahiro Arakawa, Piero Carninci, Jun Kawai, Yoshihide Hayashizaki, Takanori Kigawa, and Shigeyuki Yokoyama

Solution Structure of the SEA Domain from the Murine Homologue of Ovarian Cancer Antigen CA125 (MUC16)
J. Biol. Chem. 2004 279: 13174-13182. First Published on February 4, 2004; doi:10.1074/jbc.M309417200 [Abstract] [Full Text] [PDF]  

Ivana Sirangelo, Clorinda Malmo, Clara Iannuzzi, Antonio Mezzogiorno, Maria Rosaria Bianco, Michele Papa, and Gaetano Irace

Fibrillogenesis and Cytotoxic Activity of the Amyloid-forming Apomyoglobin Mutant W7FW14F
J. Biol. Chem. 2004 279: 13183-13189. First Published on December 30, 2003; doi:10.1074/jbc.M308207200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Hiroshi Deguchi, Subramanian Yegneswaran, and John H. Griffin

Sphingolipids as Bioactive Regulators of Thrombin Generation
J. Biol. Chem. 2004 279: 12036-12042. First Published on January 13, 2004; doi:10.1074/jbc.M302531200 [Abstract] [Full Text] [PDF]  

Abhijit Ghosh, Jeng-Jer Shieh, Chi-Jiunn Pan, and Janice Yang Chou

Histidine 167 Is the Phosphate Acceptor in Glucose-6-phosphatase- Forming a Phosphohistidine Enzyme Intermediate during Catalysis
J. Biol. Chem. 2004 279: 12479-12483. First Published on January 12, 2004; doi:10.1074/jbc.M313271200 [Abstract] [Full Text] [PDF]  

Tara R. Gaertner, Steven J. Kolodziej, Dan Wang, Ryuji Kobayashi, John M. Koomen, James K. Stoops, and M. Neal Waxham

Comparative Analyses of the Three-dimensional Structures and Enzymatic Properties of , , , and Isoforms of Ca²⁺-Calmodulin-dependent Protein Kinase II
J. Biol. Chem. 2004 279: 12484-12494. First Published on January 12, 2004; doi:10.1074/jbc.M313597200 [Abstract] [Full Text] [PDF]  

Asako Kounosu, Zhongrui Li, Nathaniel J. Cosper, Jacob E. Shokes, Robert A. Scott, Takeo Imai, Akio Urushiyama, and Toshio Iwasaki

Engineering a Three-cysteine, One-histidine Ligand Environment into a New Hyperthermophilic Archaeal Rieske-type [2Fe-2S] Ferredoxin from Sulfolobus solfataricus
J. Biol. Chem. 2004 279: 12519-12528. First Published on January 15, 2004; doi:10.1074/jbc.M305923200 [Abstract] [Full Text] [PDF] Supplemental Data  

Takamasa Uekita, Isamu Gotoh, Takeshi Kinoshita, Yoshifumi Itoh, Hiroshi Sato, Takayuki Shiomi, Yasunori Okada, and Motoharu Seiki

Membrane-type 1 Matrix Metalloproteinase Cytoplasmic Tail-binding Protein-1 Is a New Member of the Cupin Superfamily: A POSSIBLE MULTIFUNCTIONAL PROTEIN ACTING AS AN INVASION SUPPRESSOR DOWN-REGULATED IN TUMORS
J. Biol. Chem. 2004 279: 12734-12743. First Published on January 12, 2004; doi:10.1074/jbc.M309957200 [Abstract] [Full Text] [PDF]  

Christopher A. Davis, Amy S. Hearn, Bradley Fletcher, Justin Bickford, Jorge E. Garcia, Vincent Leveque, J. Andres Melendez, David N. Silverman, James Zucali, Anupam Agarwal, and Harry S. Nick

Potent Anti-tumor Effects of an Active Site Mutant of Human Manganese-Superoxide Dismutase: EVOLUTIONARY CONSERVATION OF PRODUCT INHIBITION
J. Biol. Chem. 2004 279: 12769-12776. First Published on December 18, 2003; doi:10.1074/jbc.M310623200 [Abstract] [Full Text] [PDF]  

Raimondo De Cristofaro, Sepideh Akhavan, Cosimo Altomare, Andrea Carotti, Flora Peyvandi, and Pier Mannuccio Mannucci

A Natural Prothrombin Mutant Reveals an Unexpected Influence of A-chain Structure on the Activity of Human -Thrombin
J. Biol. Chem. 2004 279: 13035-13043. First Published on January 13, 2004; doi:10.1074/jbc.M312430200 [Abstract] [Full Text] [PDF]  

S. Kumar Singh, Kun Yang, Subramanian Karthikeyan, Tu Huynh, Xuejun Zhang, Margaret A. Phillips, and Hong Zhang

The thrH Gene Product of Pseudomonas aeruginosa Is a Dual Activity Enzyme with a Novel Phosphoserine:Homoserine Phosphotransferase Activity
J. Biol. Chem. 2004 279: 13166-13173. First Published on December 29, 2003; doi:10.1074/jbc.M311393200 [Abstract] [Full Text] [PDF]  

Yongzhan Nie, Qingchuan Zhao, Yingjun Su, and Jing-Hua Yang

Subcellular Distribution of ADAR1 Isoforms Is Synergistically Determined by Three Nuclear Discrimination Signals and a Regulatory Motif
J. Biol. Chem. 2004 279: 13249-13255. First Published on January 7, 2004; doi:10.1074/jbc.M312753200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Takashi Yamamoto, Hitoshi Shimano, Yoshimi Nakagawa, Tomohiro Ide, Naoya Yahagi, Takashi Matsuzaka, Masanori Nakakuki, Akimitsu Takahashi, Hiroaki Suzuki, Hirohito Sone, Hideo Toyoshima, Ryuichiro Sato, and Nobuhiro Yamada

SREBP-1 Interacts with Hepatocyte Nuclear Factor-4 and Interferes with PGC-1 Recruitment to Suppress Hepatic Gluconeogenic Genes
J. Biol. Chem. 2004 279: 12027-12035. First Published on January 13, 2004; doi:10.1074/jbc.M310333200 [Abstract] [Full Text] [PDF]  

Jie Shang and Mark A. Lehrman

Activation of Glycogen Phosphorylase with 5-Aminoimidazole-4-Carboxamide Riboside (AICAR): ASSESSMENT OF GLYCOGEN AS A PRECURSOR OF MANNOSYL RESIDUES IN GLYCOCONJUGATES
J. Biol. Chem. 2004 279: 12076-12080. First Published on January 16, 2004; doi:10.1074/jbc.M400431200 [Abstract] [Full Text] [PDF]  

Lan Wu, Wendell Nicholson, Susan M. Knobel, Robert J. Steffner, James M. May, David W. Piston, and Alvin C. Powers

Oxidative Stress Is a Mediator of Glucose Toxicity in Insulin-secreting Pancreatic Islet Cell Lines
J. Biol. Chem. 2004 279: 12126-12134. First Published on December 19, 2003; doi:10.1074/jbc.M307097200 [Abstract] [Full Text] [PDF]  

Utpal B. Pajvani, Meredith Hawkins, Terry P. Combs, Michael W. Rajala, Tom Doebber, Joel P. Berger, John A. Wagner, Margaret Wu, Annemie Knopps, Anny H. Xiang, Kristina M. Utzschneider, Steven E. Kahn, Jerrold M. Olefsky, Thomas A. Buchanan, and Philipp E. Scherer

Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity
J. Biol. Chem. 2004 279: 12152-12162. First Published on December 29, 2003; doi:10.1074/jbc.M311113200 [Abstract] [Full Text] [PDF]  

Frederik Pauwels, Bjorn Vergauwen, and Jozef J. Van Beeumen

Physiological Characterization of Haemophilus influenzae Rd Deficient in Its Glutathione-dependent Peroxidase PGdx
J. Biol. Chem. 2004 279: 12163-12170. First Published on December 29, 2003; doi:10.1074/jbc.M312037200 [Abstract] [Full Text] [PDF]  

Tatyana V. Zharova and Andrei D. Vinogradov

Energy-dependent Transformation of F₀·F₁-ATPase in Paracoccus denitrificans Plasma Membranes
J. Biol. Chem. 2004 279: 12319-12324. First Published on January 13, 2004; doi:10.1074/jbc.M311397200 [Abstract] [Full Text] [PDF]  

Nagendra Yadava, Toby Houchens, Prasanth Potluri, and Immo E. Scheffler

Development and Characterization of a Conditional Mitochondrial Complex I Assembly System
J. Biol. Chem. 2004 279: 12406-12413. First Published on January 13, 2004; doi:10.1074/jbc.M313588200 [Abstract] [Full Text] [PDF]  

Kazuto Takasaki, Hirofumi Shoun, Masashi Yamaguchi, Kanji Takeo, Akira Nakamura, Takayuki Hoshino, and Naoki Takaya

Fungal Ammonia Fermentation, a Novel Metabolic Mechanism That Couples the Dissimilatory and Assimilatory Pathways of Both Nitrate and Ethanol: ROLE OF ACETYL CoA SYNTHETASE IN ANAEROBIC ATP SYNTHESIS
J. Biol. Chem. 2004 279: 12414-12420. First Published on January 13, 2004; doi:10.1074/jbc.M313761200 [Abstract] [Full Text] [PDF]  

Nicholas Fisher, C. Kate Castleden, Ingrid Bourges, Gael Brasseur, Genevieve Dujardin, and Brigitte Meunier

Human Disease-related Mutations in Cytochrome b Studied in Yeast
J. Biol. Chem. 2004 279: 12951-12958. First Published on January 12, 2004; doi:10.1074/jbc.M313866200 [Abstract] [Full Text] [PDF]  

George T. Hanson, Robert Aggeler, Devin Oglesbee, Mark Cannon, Roderick A. Capaldi, Roger Y. Tsien, and S. James Remington

Investigating Mitochondrial Redox Potential with Redox-sensitive Green Fluorescent Protein Indicators
J. Biol. Chem. 2004 279: 13044-13053. First Published on January 13, 2004; doi:10.1074/jbc.M312846200 [Abstract] [Full Text] [PDF]  

Qiong Guo, Charles D. Detweiler, and Ronald P. Mason

Protein Radical Formation during Lactoperoxidase-mediated Oxidation of the Suicide Substrate Glutathione: IMMUNOCHEMICAL DETECTION OF A LACTOPEROXIDASE RADICAL-DERIVED 5,5-DIMETHYL-1-PYRROLINE N-OXIDE NITRONE ADDUCT
J. Biol. Chem. 2004 279: 13272-13283. First Published on January 14, 2004; doi:10.1074/jbc.M310034200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Shuiliang Shi, Suzanne Grothe, Yiping Zhang, Maureen D. O'Connor-McCourt, A. Robin Poole, Peter J. Roughley, and John S. Mort

Link Protein Has Greater Affinity for Versican than Aggrecan
J. Biol. Chem. 2004 279: 12060-12066. First Published on January 14, 2004; doi:10.1074/jbc.M310091200 [Abstract] [Full Text] [PDF]  

Satoko Ashikari-Hada, Hiroko Habuchi, Yutaka Kariya, Nobuyuki Itoh, A. Hari Reddi, and Koji Kimata

Characterization of Growth Factor-binding Structures in Heparin/Heparan Sulfate Using an Octasaccharide Library
J. Biol. Chem. 2004 279: 12346-12354. First Published on January 5, 2004; doi:10.1074/jbc.M313523200 [Abstract] [Full Text] [PDF]  

Premkumar Dinadayala, Anne Lemassu, Pierre Granovski, Stéphane Cérantola, Nathalie Winter, and Mamadou Daffé

Revisiting the Structure of the Anti-neoplastic Glucans of Mycobacterium bovis Bacille Calmette-Guérin: STRUCTURAL ANALYSIS OF THE EXTRACELLULAR AND BOILING WATER EXTRACT-DERIVED GLUCANS OF THE VACCINE SUBSTRAINS
J. Biol. Chem. 2004 279: 12369-12378. First Published on January 10, 2004; doi:10.1074/jbc.M308908200 [Abstract] [Full Text] [PDF]  

Joanna M. Day, Anders I. Olin, Alan D. Murdoch, Ann Canfield, Takako Sasaki, Rupert Timpl, Timothy E. Hardingham, and Anders Aspberg

Alternative Splicing in the Aggrecan G3 Domain Influences Binding Interactions with Tenascin-C and Other Extracellular Matrix Proteins
J. Biol. Chem. 2004 279: 12511-12518. First Published on January 13, 2004; doi:10.1074/jbc.M400242200 [Abstract] [Full Text] [PDF]  

Katrin Mani, Fang Cheng, Birgitta Havsmark, Samuel David, and Lars-Åke Fransson

Involvement of Glycosylphosphatidylinositol-linked Ceruloplasmin in the Copper/Zinc-Nitric Oxide-dependent Degradation of Glypican-1 Heparan Sulfate in Rat C6 Glioma Cells
J. Biol. Chem. 2004 279: 12918-12923. First Published on January 5, 2004; doi:10.1074/jbc.M313678200 [Abstract] [Full Text] [PDF]  

Li Tan, Feng Qiu, Derek T. A. Lamport, and Marcia J. Kieliszewski

Structure of a Hydroxyproline (Hyp)-Arabinogalactan Polysaccharide from Repetitive Ala-Hyp Expressed in Transgenic Nicotiana tabacum
J. Biol. Chem. 2004 279: 13156-13165. First Published on January 14, 2004; doi:10.1074/jbc.M311864200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Hyeon-Son Choi, Avula Sreenivas, Gil-Soo Han, and George M. Carman

Regulation of Phospholipid Synthesis in the Yeast cki1 eki1 Mutant Defective in the Kennedy Pathway: THE CHO1-ENCODED PHOSPHATIDYLSERINE SYNTHASE IS REGULATED BY mRNA STABILITY
J. Biol. Chem. 2004 279: 12081-12087. First Published on January 21, 2004; doi:10.1074/jbc.M400297200 [Abstract] [Full Text] [PDF]  

Dorit Avrahami and Yechiel Shai

A New Group of Antifungal and Antibacterial Lipopeptides Derived from Non-membrane Active Peptides Conjugated to Palmitic Acid
J. Biol. Chem. 2004 279: 12277-12285. First Published on January 6, 2004; doi:10.1074/jbc.M312260200 [Abstract] [Full Text] [PDF]  

Stephen T. Thuahnai, Sissel Lund-Katz, Padmaja Dhanasekaran, Margarita de la Llera-Moya, Margery A. Connelly, David L. Williams, George H. Rothblat, and Michael C. Phillips

Scavenger Receptor Class B Type I-mediated Cholesteryl Ester-selective Uptake and Efflux of Unesterified Cholesterol: INFLUENCE OF HIGH DENSITY LIPOPROTEIN SIZE AND STRUCTURE
J. Biol. Chem. 2004 279: 12448-12455. First Published on January 12, 2004; doi:10.1074/jbc.M311718200 [Abstract] [Full Text] [PDF]  

Edgar B. Cahoon and Anthony J. Kinney

Dimorphecolic Acid Is Synthesized by the Coordinate Activities of Two Divergent ¹²-Oleic Acid Desaturases
J. Biol. Chem. 2004 279: 12495-12502. First Published on January 12, 2004; doi:10.1074/jbc.M314329200 [Abstract] [Full Text] [PDF]  

Deron R. Herr, Henrik Fyrst, Michael B. Creason, Van H. Phan, Julie D. Saba, and Greg L. Harris

Characterization of the Drosophila Sphingosine Kinases and Requirement for Sk2 in Normal Reproductive Function
J. Biol. Chem. 2004 279: 12685-12694. First Published on January 13, 2004; doi:10.1074/jbc.M310647200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Yang Chao and Dax Fu

Kinetic Study of the Antiport Mechanism of an Escherichia coli Zinc Transporter, ZitB
J. Biol. Chem. 2004 279: 12043-12050. First Published on January 10, 2004; doi:10.1074/jbc.M313510200 [Abstract] [Full Text] [PDF]  

Dieter D'hoedt, Klaus Hirzel, Paola Pedarzani, and Martin Stocker

Domain Analysis of the Calcium-activated Potassium Channel SK1 from Rat Brain: FUNCTIONAL EXPRESSION AND TOXIN SENSITIVITY
J. Biol. Chem. 2004 279: 12088-12092. First Published on February 4, 2004; doi:10.1074/jbc.C300382200 [Abstract] [Full Text] [PDF]  

Yoko Dohke, Young S. Oh, Indu S. Ambudkar, and R. James Turner

Biogenesis and Topology of the Transient Receptor Potential Ca²⁺ Channel TRPC1
J. Biol. Chem. 2004 279: 12242-12248. First Published on January 5, 2004; doi:10.1074/jbc.M312456200 [Abstract] [Full Text] [PDF]  

Amy K. Wernimont, Liliya A. Yatsunyk, and Amy C. Rosenzweig

Binding of Copper(I) by the Wilson Disease Protein and Its Copper Chaperone
J. Biol. Chem. 2004 279: 12269-12276. First Published on January 6, 2004; doi:10.1074/jbc.M311213200 [Abstract] [Full Text] [PDF]  

Koji Koike, Gwenaëlle Conseil, Elaine M. Leslie, Roger G. Deeley, and Susan P. C. Cole

Identification of Proline Residues in the Core Cytoplasmic and Transmembrane Regions of Multidrug Resistance Protein 1 (MRP1/ABCC1) Important for Transport Function, Substrate Specificity, and Nucleotide Interactions
J. Biol. Chem. 2004 279: 12325-12336. First Published on January 13, 2004; doi:10.1074/jbc.M311435200 [Abstract] [Full Text] [PDF]  

Suzanne C. Hoppins and Frank E. Nargang

The Tim8-Tim13 Complex of Neurospora crassa Functions in the Assembly of Proteins into Both Mitochondrial Membranes
J. Biol. Chem. 2004 279: 12396-12405. First Published on January 13, 2004; doi:10.1074/jbc.M313037200 [Abstract] [Full Text] [PDF]  

Keiji Mitsui, Fumihiro Ochi, Norihiro Nakamura, Yoshihide Doi, Hiroki Inoue, and Hiroshi Kanazawa

A Novel Membrane Protein Capable of Binding the Na⁺/H⁺ Antiporter (Nha1p) Enhances the Salinity-resistant Cell Growth of Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 12438-12447. First Published on January 12, 2004; doi:10.1074/jbc.M310806200 [Abstract] [Full Text] [PDF]  

Hisao Yamamura, Shinya Ugawa, Takashi Ueda, Masataka Nagao, and Shoichi Shimada

Protons Activate the -Subunit of the Epithelial Na⁺ Channel in Humans
J. Biol. Chem. 2004 279: 12529-12534. First Published on January 15, 2004; doi:10.1074/jbc.M400274200 [Abstract] [Full Text] [PDF]  

Myung-Hee Kim and Louis B. Hersh

The Vesicular Acetylcholine Transporter Interacts with Clathrin-associated Adaptor Complexes AP-1 and AP-2
J. Biol. Chem. 2004 279: 12580-12587. First Published on January 14, 2004; doi:10.1074/jbc.M310681200 [Abstract] [Full Text] [PDF]  

Marc Fransen, Ilse Vastiau, Chantal Brees, Vanessa Brys, Guy P. Mannaerts, and Paul P. Van Veldhoven

Potential Role for Pex19p in Assembly of PTS-Receptor Docking Complexes
J. Biol. Chem. 2004 279: 12615-12624. First Published on January 10, 2004; doi:10.1074/jbc.M304941200 [Abstract] [Full Text] [PDF]  

Rainer Fischer, Karsten Köhler, Mariola Fotin-Mleczek, and Roland Brock

A Stepwise Dissection of the Intracellular Fate of Cationic Cell-penetrating Peptides
J. Biol. Chem. 2004 279: 12625-12635. First Published on January 5, 2004; doi:10.1074/jbc.M311461200 [Abstract] [Full Text] [PDF]  

Qi Zhang, Tina Pangrsic, Marko Kreft, Mojca Krzan, Nianzhen Li, Jai-Yoon Sul, Michael Halassa, Elisabeth Van Bockstaele, Robert Zorec, and Philip G. Haydon

Fusion-related Release of Glutamate from Astrocytes
J. Biol. Chem. 2004 279: 12724-12733. First Published on January 13, 2004; doi:10.1074/jbc.M312845200 [Abstract] [Full Text] [PDF] Supplemental Data  

Rashi Gautam, Sreenivasulu Chintala, Wei Li, Qing Zhang, Jian Tan, Edward K. Novak, Santiago M. Di Pietro, Esteban C. Dell'Angelica, and Richard T. Swank

The Hermansky-Pudlak Syndrome 3 (Cocoa) Protein Is a Component of the Biogenesis of Lysosome-related Organelles Complex-2 (BLOC-2)
J. Biol. Chem. 2004 279: 12935-12942. First Published on January 12, 2004; doi:10.1074/jbc.M311311200 [Abstract] [Full Text] [PDF]  

Christian Appenzeller-Herzog, Annie-Claude Roche, Oliver Nufer, and Hans-Peter Hauri

pH-induced Conversion of the Transport Lectin ERGIC-53 Triggers Glycoprotein Release
J. Biol. Chem. 2004 279: 12943-12950. First Published on January 12, 2004; doi:10.1074/jbc.M313245200 [Abstract] [Full Text] [PDF]  

Peter J. Mohler, Jonathan Q. Davis, Lydia H. Davis, Janis A. Hoffman, Peter Michaely, and Vann Bennett

Inositol 1,4,5-Trisphosphate Receptor Localization and Stability in Neonatal Cardiomyocytes Requires Interaction with Ankyrin-B
J. Biol. Chem. 2004 279: 12980-12987. First Published on January 13, 2004; doi:10.1074/jbc.M313979200 [Abstract] [Full Text] [PDF]  

Mary P. Gillam, Aniket R. Sidhaye, Eun Jig Lee, Jonas Rutishauser, Catherine Waeber Stephan, and Peter Kopp

Functional Characterization of Pendrin in a Polarized Cell System: EVIDENCE FOR PENDRIN-MEDIATED APICAL IODIDE EFFLUX
J. Biol. Chem. 2004 279: 13004-13010. First Published on January 8, 2004; doi:10.1074/jbc.M313648200 [Abstract] [Full Text] [PDF]  

Mitsunori Fukuda, Eiko Kanno, and Akitsugu Yamamoto

Rabphilin and Noc2 Are Recruited to Dense-core Vesicles through Specific Interaction with Rab27A in PC12 Cells
J. Biol. Chem. 2004 279: 13065-13075. First Published on January 13, 2004; doi:10.1074/jbc.M306812200 [Abstract] [Full Text] [PDF]  

Simon Hebeisen, Alexander Biela, Bernd Giese, Gerhard Müller-Newen, Patricia Hidalgo, and Christoph Fahlke

The Role of the Carboxyl Terminus in ClC Chloride Channel Function
J. Biol. Chem. 2004 279: 13140-13147. First Published on January 12, 2004; doi:10.1074/jbc.M312649200 [Abstract] [Full Text] [PDF]  

Peter A. Keyel, Simon C. Watkins, and Linton M. Traub

Endocytic Adaptor Molecules Reveal an Endosomal Population of Clathrin by Total Internal Reflection Fluorescence Microscopy
J. Biol. Chem. 2004 279: 13190-13204. First Published on January 12, 2004; doi:10.1074/jbc.M312717200 [Abstract] [Full Text] [PDF] Supplemental Data  

Mechanisms Of Signal Transduction:

Sarah J. McLeod, Andrew J. Shum, Rosaline L. Lee, Fumio Takei, and Michael R. Gold

The Rap GTPases Regulate Integrin-mediated Adhesion, Cell Spreading, Actin Polymerization, and Pyk2 Tyrosine Phosphorylation in B Lymphocytes
J. Biol. Chem. 2004 279: 12009-12019. First Published on December 29, 2003; doi:10.1074/jbc.M313098200 [Abstract] [Full Text] [PDF]  

Miriam Gensler, Marcus Buschbeck, and Axel Ullrich

Negative Regulation of HER2 Signaling by the PEST-type Protein-tyrosine Phosphatase BDP1
J. Biol. Chem. 2004 279: 12110-12116. First Published on December 2, 2003; doi:10.1074/jbc.M309527200 [Abstract] [Full Text] [PDF]  

Junjiro Horiuchi, Wei Jiang, Hong Zhou, Priscilla Wu, and Jerry C. P. Yin

Phosphorylation of Conserved Casein Kinase Sites Regulates cAMP-response Element-binding Protein DNA Binding in Drosophila
J. Biol. Chem. 2004 279: 12117-12125. First Published on December 15, 2003; doi:10.1074/jbc.M212839200 [Abstract] [Full Text] [PDF]  

Paola Pichiule, Juan C. Chavez, and Joseph C. LaManna

Hypoxic Regulation of Angiopoietin-2 Expression in Endothelial Cells
J. Biol. Chem. 2004 279: 12171-12180. First Published on December 30, 2003; doi:10.1074/jbc.M305146200 [Abstract] [Full Text] [PDF]  

Sadayuki Ochi, Masataka Oda, Hisaaki Matsuda, Syusuke Ikari, and Jun Sakurai

Clostridium perfringens -Toxin Activates the Sphingomyelin Metabolism System in Sheep Erythrocytes
J. Biol. Chem. 2004 279: 12181-12189. First Published on December 30, 2003; doi:10.1074/jbc.M307046200 [Abstract] [Full Text] [PDF]  

Ken-ichi Ogushi, Akihiro Wada, Takuro Niidome, Tatsuya Okuda, Rafael Llanes, Masaaki Nakayama, Yoshito Nishi, Hisao Kurazono, Kelly D. Smith, Alan Aderem, Joel Moss, and Toshiya Hirayama

Gangliosides Act as Co-receptors for Salmonella enteritidis FliC and Promote FliC Induction of Human -Defensin-2 Expression in Caco-2 Cells
J. Biol. Chem. 2004 279: 12213-12219. First Published on January 5, 2004; doi:10.1074/jbc.M307944200 [Abstract] [Full Text] [PDF]  

Andrew Street, Andrew Macdonald, Katherine Crowder, and Mark Harris

The Hepatitis C Virus NS5A Protein Activates a Phosphoinositide 3-Kinase-dependent Survival Signaling Cascade
J. Biol. Chem. 2004 279: 12232-12241. First Published on January 5, 2004; doi:10.1074/jbc.M312245200 [Abstract] [Full Text] [PDF]  

Julie Bayle, Sébastien Letard, Ronald Frank, Patrice Dubreuil, and Paulo De Sepulveda

Suppressor of Cytokine Signaling 6 Associates with KIT and Regulates KIT Receptor Signaling
J. Biol. Chem. 2004 279: 12249-12259. First Published on January 5, 2004; doi:10.1074/jbc.M313381200 [Abstract] [Full Text] [PDF]  

Carles Cantó, Elisabeth Suárez, José M. Lizcano, Elisenda Griñó, Peter R. Shepherd, Lee G. D. Fryer, David Carling, Joan Bertran, Manuel Palacín, Antonio Zorzano, and Anna Gumà

Neuregulin Signaling on Glucose Transport in Muscle Cells
J. Biol. Chem. 2004 279: 12260-12268. First Published on January 6, 2004; doi:10.1074/jbc.M308554200 [Abstract] [Full Text] [PDF]  

Chiung-Chun Huang, Jia-Lin You, Mei-Ying Wu, and Kuei-Sen Hsu

Rap1-induced p38 Mitogen-activated Protein Kinase Activation Facilitates AMPA Receptor Trafficking via the GDI·Rab5 Complex: POTENTIAL ROLE IN (S)-3,5-DIHYDROXYPHENYLGLYCINE-INDUCED LONG TERM DEPRESSION
J. Biol. Chem. 2004 279: 12286-12292. First Published on January 6, 2004; doi:10.1074/jbc.M312868200 [Abstract] [Full Text] [PDF]  

Soichiro Usui, Naotoshi Sugimoto, Noriko Takuwa, Satoru Sakagami, Shigeo Takata, Shuichi Kaneko, and Yoh Takuwa

Blood Lipid Mediator Sphingosine 1-Phosphate Potently Stimulates Platelet-derived Growth Factor-A and -B Chain Expression through S1P₁-G_i-Ras-MAPK-dependent Induction of Krüppel-like Factor 5
J. Biol. Chem. 2004 279: 12300-12311. First Published on January 7, 2004; doi:10.1074/jbc.M305025200 [Abstract] [Full Text] [PDF]  

Nicolas Charles, Renato C. Monteiro, and Marc Benhamou

p28, a Novel IgE Receptor-associated Protein, Is a Sensor of Receptor Occupation by Its Ligand in Mast Cells
J. Biol. Chem. 2004 279: 12312-12318. First Published on January 8, 2004; doi:10.1074/jbc.M309456200 [Abstract] [Full Text] [PDF]  

Ana M. Gamero, Shuji Sakamoto, Javier Montenegro, and Andrew C. Larner

Identification of a Novel Conserved Motif in the STAT Family That Is Required for Tyrosine Phosphorylation
J. Biol. Chem. 2004 279: 12379-12385. First Published on January 13, 2004; doi:10.1074/jbc.M310787200 [Abstract] [Full Text] [PDF]  

Christof Zitt, Bettina Strauss, Eva C. Schwarz, Nicola Spaeth, Georg Rast, Armin Hatzelmann, and Markus Hoth

Potent Inhibition of Ca²⁺ Release-activated Ca²⁺ Channels and T-lymphocyte Activation by the Pyrazole Derivative BTP2
J. Biol. Chem. 2004 279: 12427-12437. First Published on January 12, 2004; doi:10.1074/jbc.M309297200 [Abstract] [Full Text] [PDF]  

Julio Alvarez, Jana Hamplova, Annette Hohaus, Ingo Morano, Hannelore Haase, and Guy Vassort

Calcium Current in Rat Cardiomyocytes Is Modulated by the Carboxyl-terminal Ahnak Domain
J. Biol. Chem. 2004 279: 12456-12461. First Published on January 12, 2004; doi:10.1074/jbc.M312177200 [Abstract] [Full Text] [PDF]  

Sharon Weiss, Thanh Doan, Kenneth E. Bernstein, and Nathan Dascal

Modulation of Cardiac Ca²⁺ Channel by G_q-activating Neurotransmitters Reconstituted in Xenopus Oocytes
J. Biol. Chem. 2004 279: 12503-12510. First Published on January 13, 2004; doi:10.1074/jbc.M310196200 [Abstract] [Full Text] [PDF]  

Katalin Karikó, Houping Ni, John Capodici, Marc Lamphier, and Drew Weissman

mRNA Is an Endogenous Ligand for Toll-like Receptor 3
J. Biol. Chem. 2004 279: 12542-12550. First Published on January 16, 2004; doi:10.1074/jbc.M310175200 [Abstract] [Full Text] [PDF]  

Ralph M. Fritsch, Dieter Saur, Manfred Kurjak, Daniela Oesterle, Jens Schlossmann, Angela Geiselhöringer, Franz Hofmann, and Hans-Dieter Allescher

InsP₃R-associated cGMP Kinase Substrate (IRAG) Is Essential for Nitric Oxide-induced Inhibition of Calcium Signaling in Human Colonic Smooth Muscle
J. Biol. Chem. 2004 279: 12551-12559. First Published on January 18, 2004; doi:10.1074/jbc.M313365200 [Abstract] [Full Text] [PDF]  

Qiang Zhao, Frank Boschelli, Avrom J. Caplan, and Kim T. Arndt

Identification of a Conserved Sequence Motif That Promotes Cdc37 and Cyclin D1 Binding to Cdk4
J. Biol. Chem. 2004 279: 12560-12564. First Published on December 30, 2003; doi:10.1074/jbc.M308242200 [Abstract] [Full Text] [PDF]  

Francis C. Peterson, E. Sonay Elgin, Timothy J. Nelson, Fuming Zhang, Theresa J. Hoeger, Robert J. Linhardt, and Brian F. Volkman

Identification and Characterization of a Glycosaminoglycan Recognition Element of the C Chemokine Lymphotactin
J. Biol. Chem. 2004 279: 12598-12604. First Published on January 5, 2004; doi:10.1074/jbc.M311633200 [Abstract] [Full Text] [PDF]  

Mireille Toy-Miou-Leong, Catherine Llorens Cortes, Alain Beaudet, William Rostène, and Patricia Forgez

Receptor Trafficking via the Perinuclear Recycling Compartment Accompanied by Cell Division Is Necessary for Permanent Neurotensin Cell Sensitization and Leads to Chronic Mitogen-activated Protein Kinase Activation
J. Biol. Chem. 2004 279: 12636-12646. First Published on December 29, 2003; doi:10.1074/jbc.M303384200 [Abstract] [Full Text] [PDF]  

Kotha Subbaramaiah, Kazuhiko Yoshimatsu, Ellen Scherl, Kiron M. Das, Kenneth D. Glazier, Dragan Golijanin, Robert A. Soslow, Tadashi Tanabe, Hiroaki Naraba, and Andrew J. Dannenberg

Microsomal Prostaglandin E Synthase-1 Is Overexpressed in Inflammatory Bowel Disease: EVIDENCE FOR INVOLVEMENT OF THE TRANSCRIPTION FACTOR Egr-1
J. Biol. Chem. 2004 279: 12647-12658. First Published on January 13, 2004; doi:10.1074/jbc.M312972200 [Abstract] [Full Text] [PDF]  

Taketoshi Kajimoto, Yasuhito Shirai, Norio Sakai, Toshiyoshi Yamamoto, Hidenori Matsuzaki, Ushio Kikkawa, and Naoaki Saito

Ceramide-induced Apoptosis by Translocation, Phosphorylation, and Activation of Protein Kinase C in the Golgi Complex
J. Biol. Chem. 2004 279: 12668-12676. First Published on January 10, 2004; doi:10.1074/jbc.M312350200 [Abstract] [Full Text] [PDF]  

Marjon van Slegtenhorst, Erikka Carr, Radka Stoyanova, Warren D. Kruger, and Elizabeth Petri Henske

Tsc1⁺ and tsc2⁺ Regulate Arginine Uptake and Metabolism in Schizosaccharomyces pombe
J. Biol. Chem. 2004 279: 12706-12713. First Published on January 12, 2004; doi:10.1074/jbc.M313874200 [Abstract] [Full Text] [PDF]  

Nobuko Hamasaki-Katagiri, Tatiana Molchanova, Kazuyo Takeda, and James B. Ames

Fission Yeast Homolog of Neuronal Calcium Sensor-1 (Ncs1p) Regulates Sporulation and Confers Calcium Tolerance
J. Biol. Chem. 2004 279: 12744-12754. First Published on January 13, 2004; doi:10.1074/jbc.M311895200 [Abstract] [Full Text] [PDF] Supplemental Data  

Jerome F. Sah, Sivaprakasam Balasubramanian, Richard L. Eckert, and Ellen A. Rorke

Epigallocatechin-3-gallate Inhibits Epidermal Growth Factor Receptor Signaling Pathway: EVIDENCE FOR DIRECT INHIBITION OF ERK1/2 AND AKT KINASES
J. Biol. Chem. 2004 279: 12755-12762. First Published on December 29, 2003; doi:10.1074/jbc.M312333200 [Abstract] [Full Text] [PDF]  

Alejandro Balbis, Gerardo Baquiran, Victor Dumas, and Barry I. Posner

Effect of Inhibiting Vacuolar Acidification on Insulin Signaling in Hepatocytes
J. Biol. Chem. 2004 279: 12777-12785. First Published on December 19, 2003; doi:10.1074/jbc.M311493200 [Abstract] [Full Text] [PDF]  

Li Cheng, Gwendolyn M. Mahon, Elena V. Kostenko, and Ian P. Whitehead

Pleckstrin Homology Domain-mediated Activation of the Rho-specific Guanine Nucleotide Exchange Factor Dbs by Rac1
J. Biol. Chem. 2004 279: 12786-12793. First Published on December 30, 2003; doi:10.1074/jbc.M313099200 [Abstract] [Full Text] [PDF]  

Angelique W. Whitehurst, Fred L. Robinson, Mary Shannon Moore, and Melanie H. Cobb

The Death Effector Domain Protein PEA-15 Prevents Nuclear Entry of ERK2 by Inhibiting Required Interactions
J. Biol. Chem. 2004 279: 12840-12847. First Published on January 5, 2004; doi:10.1074/jbc.M310031200 [Abstract] [Full Text] [PDF]  

Sebastien Pili-Floury, François Leulier, Kuniaki Takahashi, Kaoru Saigo, Emmanuel Samain, Ryu Ueda, and Bruno Lemaitre

In Vivo RNA Interference Analysis Reveals an Unexpected Role for GNBP1 in the Defense against Gram-positive Bacterial Infection in Drosophila Adults
J. Biol. Chem. 2004 279: 12848-12853. First Published on January 13, 2004; doi:10.1074/jbc.M313324200 [Abstract] [Full Text] [PDF]  

Ming Zhao, Mei Qiao, Stephen E. Harris, Babatunde O. Oyajobi, Gregory R. Mundy, and Di Chen

Smurf1 Inhibits Osteoblast Differentiation and Bone Formation in Vitro and in Vivo
J. Biol. Chem. 2004 279: 12854-12859. First Published on December 29, 2003; doi:10.1074/jbc.M313294200 [Abstract] [Full Text] [PDF]  

Yolanda Romsicki, Mark Reece, Jacques-Yves Gauthier, Ernest Asante-Appiah, and Brian P. Kennedy

Protein Tyrosine Phosphatase-1B Dephosphorylation of the Insulin Receptor Occurs in a Perinuclear Endosome Compartment in Human Embryonic Kidney 293 Cells
J. Biol. Chem. 2004 279: 12868-12875. First Published on January 13, 2004; doi:10.1074/jbc.M309600200 [Abstract] [Full Text] [PDF]  

Yingzi Yue, Jaqueline Lypowy, Nadia Hedhli, and Maha Abdellatif

Ras GTPase-activating Protein Binds to Akt and Is Required for Its Activation
J. Biol. Chem. 2004 279: 12883-12889. First Published on January 5, 2004; doi:10.1074/jbc.M312308200 [Abstract] [Full Text] [PDF]  

Paramita Chakrabarty, Dhruv K. Sethi, Narendra Padhan, Kanwal J. Kaur, Dinakar M. Salunke, Sudha Bhattacharya, and Alok Bhattacharya

Identification and Characterization of EhCaBP2: A SECOND MEMBER OF THE CALCIUM-BINDING PROTEIN FAMILY OF THE PROTOZOAN PARASITE ENTAMOEBA HISTOLYTICA
J. Biol. Chem. 2004 279: 12898-12908. First Published on January 7, 2004; doi:10.1074/jbc.M304716200 [Abstract] [Full Text] [PDF]  

Jason I. E. Bruce, David R. Giovannucci, Greg Blinder, Trevor J. Shuttleworth, and David I. Yule

Modulation of [Ca²⁺]_i Signaling Dynamics and Metabolism by Perinuclear Mitochondria in Mouse Parotid Acinar Cells
J. Biol. Chem. 2004 279: 12909-12917. First Published on December 29, 2003; doi:10.1074/jbc.M309070200 [Abstract] [Full Text] [PDF]  

Junya Kawasaki, George E. Davis, and Michael J. Davis

Regulation of Ca²⁺-dependent K⁺ Current by _v3 Integrin Engagement in Vascular Endothelium
J. Biol. Chem. 2004 279: 12959-12966. First Published on January 13, 2004; doi:10.1074/jbc.M313791200 [Abstract] [Full Text] [PDF]  

Oleg Tikhomirov and Graham Carpenter

Ligand-induced, p38-dependent Apoptosis in Cells Expressing High Levels of Epidermal Growth Factor Receptor and ErbB-2
J. Biol. Chem. 2004 279: 12988-12996. First Published on January 7, 2004; doi:10.1074/jbc.M311655200 [Abstract] [Full Text] [PDF]  

Yoshihiro Yasui, Takeshi Urano, Aie Kawajiri, Koh-ichi Nagata, Masaaki Tatsuka, Hideyuki Saya, Koichi Furukawa, Toshitada Takahashi, Ichiro Izawa, and Masaki Inagaki

Autophosphorylation of a Newly Identified Site of Aurora-B Is Indispensable for Cytokinesis
J. Biol. Chem. 2004 279: 12997-13003. First Published on January 13, 2004; doi:10.1074/jbc.M311128200 [Abstract] [Full Text] [PDF]  

Wojciech Swiatek, I-Chun Tsai, Laura Klimowski, Andrea Pepler, Janet Barnette, H. Joseph Yost, and David M. Virshup

Regulation of Casein Kinase I Activity by Wnt Signaling
J. Biol. Chem. 2004 279: 13011-13017. First Published on January 13, 2004; doi:10.1074/jbc.M304682200 [Abstract] [Full Text] [PDF]  

Simona Denti, Alessandra Sirri, Alessandra Cheli, Lars Rogge, Giulio Innamorati, Stella Putignano, Monica Fabbri, Ruggero Pardi, and Elisabetta Bianchi

RanBPM Is a Phosphoprotein That Associates with the Plasma Membrane and Interacts with the Integrin LFA-1
J. Biol. Chem. 2004 279: 13027-13034. First Published on January 13, 2004; doi:10.1074/jbc.M313515200 [Abstract] [Full Text] [PDF]  

Xiaorui Yu, Raju V. S. Rajala, James F. McGinnis, Feng Li, Robert E. Anderson, Xiaorong Yan, Sheng Li, Rajesh V. Elias, Ryan R. Knapp, Xiaohong Zhou, and Wei Cao

Involvement of Insulin/Phosphoinositide 3-Kinase/Akt Signal Pathway in 17-Estradiol-mediated Neuroprotection
J. Biol. Chem. 2004 279: 13086-13094. First Published on January 6, 2004; doi:10.1074/jbc.M313283200 [Abstract] [Full Text] [PDF]  

Lianne B. Dale, Jennifer L. Seachrist, Andy V. Babwah, and Stephen S. G. Ferguson

Regulation of Angiotensin II Type 1A Receptor Intracellular Retention, Degradation, and Recycling by Rab5, Rab7, and Rab11 GTPases
J. Biol. Chem. 2004 279: 13110-13118. First Published on January 7, 2004; doi:10.1074/jbc.M313333200 [Abstract] [Full Text] [PDF]  

Enrica Audero, Ilaria Cascone, Fabrizio Maniero, Lucia Napione, Marco Arese, Luisa Lanfrancone, and Federico Bussolino

Adaptor ShcA Protein Binds Tyrosine Kinase Tie2 Receptor and Regulates Migration and Sprouting but Not Survival of Endothelial Cells
J. Biol. Chem. 2004 279: 13224-13233. First Published on December 9, 2003; doi:10.1074/jbc.M307456200 [Abstract] [Full Text] [PDF]  

Shingo Suzuki, Ali Ferjani, Iwane Suzuki, and Norio Murata

The SphS-SphR Two Component System Is the Exclusive Sensor for the Induction of Gene Expression in Response to Phosphate Limitation in Synechocystis
J. Biol. Chem. 2004 279: 13234-13240. First Published on January 5, 2004; doi:10.1074/jbc.M313358200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Ming Chang Hu, David Wasserman, Sunny Hartwig, and Norman D. Rosenblum

p38^MAPK Acts in the BMP7-dependent Stimulatory Pathway during Epithelial Cell Morphogenesis and Is Regulated by Smad1
J. Biol. Chem. 2004 279: 12051-12059. First Published on January 12, 2004; doi:10.1074/jbc.M310526200 [Abstract] [Full Text] [PDF]  

Yumi Nakai, Noriko Umeda, Tsutomu Suzuki, Masato Nakai, Hideyuki Hayashi, Kimitsuna Watanabe, and Hiroyuki Kagamiyama

Yeast Nfs1p Is Involved in Thio-modification of Both Mitochondrial and Cytoplasmic tRNAs
J. Biol. Chem. 2004 279: 12363-12368. First Published on January 13, 2004; doi:10.1074/jbc.M312448200 [Abstract] [Full Text] [PDF]  

Gemma Bellí, María Micaela Molina, José García-Martínez, José E. Pérez-Ortín, and Enrique Herrero

Saccharomyces cerevisiae Glutaredoxin 5-deficient Cells Subjected to Continuous Oxidizing Conditions Are Affected in the Expression of Specific Sets of Genes
J. Biol. Chem. 2004 279: 12386-12395. First Published on January 13, 2004; doi:10.1074/jbc.M311879200 [Abstract] [Full Text] [PDF]  

Colin Rickman, Deborah A. Archer, Frederic A. Meunier, Molly Craxton, Mitsunori Fukuda, Robert D. Burgoyne, and Bazbek Davletov

Synaptotagmin Interaction with the Syntaxin/SNAP-25 Dimer Is Mediated by an Evolutionarily Conserved Motif and Is Sensitive to Inositol Hexakisphosphate
J. Biol. Chem. 2004 279: 12574-12579. First Published on January 6, 2004; doi:10.1074/jbc.M310710200 [Abstract] [Full Text] [PDF]  

Richard M. Harwell, Benjamin B. Mull, Donald C. Porter, and Khandan Keyomarsi

Activation of Cyclin-dependent Kinase 2 by Full Length and Low Molecular Weight Forms of Cyclin E in Breast Cancer Cells
J. Biol. Chem. 2004 279: 12695-12705. First Published on December 29, 2003; doi:10.1074/jbc.M313407200 [Abstract] [Full Text] [PDF]  

Yin-Lau Lee, Kai-Fai Lee, Jia-Sen Xu, Qing-Yu He, Jen-Fu Chiu, Will M. Lee, John M. Luk, and William S. B. Yeung

The Embryotrophic Activity of Oviductal Cell-derived Complement C3b and iC3b, a Novel Function of Complement Protein in Reproduction
J. Biol. Chem. 2004 279: 12763-12768. First Published on December 29, 2003; doi:10.1074/jbc.M311160200 [Abstract] [Full Text] [PDF]  

Miro Brajenovic, Gerard Joberty, Bernhard Küster, Tewis Bouwmeester, and Gerard Drewes

Comprehensive Proteomic Analysis of Human Par Protein Complexes Reveals an Interconnected Protein Network
J. Biol. Chem. 2004 279: 12804-12811. First Published on December 15, 2003; doi:10.1074/jbc.M312171200 [Abstract] [Full Text] [PDF] Supplemental Data  

Gwendolyn T. Wong, Denise Manfra, Frederique M. Poulet, Qi Zhang, Hubert Josien, Thomas Bara, Laura Engstrom, Maria Pinzon-Ortiz, Jay S. Fine, Hu-Jung J. Lee, Lili Zhang, Guy A. Higgins, and Eric M. Parker

Chronic Treatment with the -Secretase Inhibitor LY-411,575 Inhibits -Amyloid Peptide Production and Alters Lymphopoiesis and Intestinal Cell Differentiation
J. Biol. Chem. 2004 279: 12876-12882. First Published on January 6, 2004; doi:10.1074/jbc.M311652200 [Abstract] [Full Text] [PDF]  

Rajnish Bharadwaj, Wei Qi, and Hongtao Yu

Identification of Two Novel Components of the Human NDC80 Kinetochore Complex
J. Biol. Chem. 2004 279: 13076-13085. First Published on December 29, 2003; doi:10.1074/jbc.M310224200 [Abstract] [Full Text] [PDF] Supplemental Data  

Nikolai A. Timchenko, Roma Patel, Polina Iakova, Zong-Jin Cai, Ling Quan, and Lubov T. Timchenko

Overexpression of CUG Triplet Repeat-binding Protein, CUGBP1, in Mice Inhibits Myogenesis
J. Biol. Chem. 2004 279: 13129-13139. First Published on January 13, 2004; doi:10.1074/jbc.M312923200 [Abstract] [Full Text] [PDF]  

Guoyan Wang, Anita Woods, Shalev Sabari, Luca Pagnotta, Lee-Anne Stanton, and Frank Beier

RhoA/ROCK Signaling Suppresses Hypertrophic Chondrocyte Differentiation
J. Biol. Chem. 2004 279: 13205-13214. First Published on January 15, 2004; doi:10.1074/jbc.M311427200 [Abstract] [Full Text] [PDF]  

Makoto Takano, Yuhei Koyama, Hiromi Ito, Satomi Hoshino, Hiroshi Onogi, Masatoshi Hagiwara, Kazuhiro Furukawa, and Tsuneyoshi Horigome

Regulation of Binding of Lamin B Receptor to Chromatin by SR Protein Kinase and cdc2 Kinase in Xenopus Egg Extracts
J. Biol. Chem. 2004 279: 13265-13271. First Published on January 12, 2004; doi:10.1074/jbc.M308854200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Jinping Lai, Jeremy Chien, Julie Staub, Rajeswari Avula, L. Eddie Greene, Tori A. Matthews, David I. Smith, Scott H. Kaufmann, Lewis R. Roberts, and Viji Shridhar

Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer. Vol. 278 (2003) 23107-23117
J. Biol. Chem. 2004 279: 13284. [Full Text] [PDF]  

Ya-Xiong Tao, Nathan B. Johnson, and Deborah L. Segaloff

Constitutive and agonist-dependent self-association of the cell surface human lutropin receptor. Vol. 279 (2004) 5904-5914
J. Biol. Chem. 2004 279: 13284. [Full Text] [PDF]  

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