JBC Focus on PI3-Kinase with Echelon

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 Table of Contents: Jun 11 2004; 279 (24)   [Index by Author]  [Cover Figure and Caption]
       Minireviews
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Minireviews:

Charlotte L. Hanson and Carol V. Robinson
Protein-Nucleic Acid Interactions and the Expanding Role of Mass Spectrometry
J. Biol. Chem. 2004 279: 24907-24910. First Published on March 31, 2004; doi:10.1074/jbc.R300037200 [Abstract] [Full Text] [PDF]  

Accelerated Publications:

Alam Nur-E-Kamal, Stephane R. Gross, Zui Pan, Zita Balklava, Jianjie Ma, and Leroy F. Liu
Nuclear Translocation of Cytochrome c during Apoptosis
J. Biol. Chem. 2004 279: 24911-24914. First Published on April 8, 2004; doi:10.1074/jbc.C400051200 [Abstract] [Full Text] [PDF]  

Narendra Kumar and Seema Khurana
Identification of a Functional Switch for Actin Severing by Cytoskeletal Proteins
J. Biol. Chem. 2004 279: 24915-24918. First Published on April 14, 2004; doi:10.1074/jbc.C400110200 [Abstract] [Full Text] [PDF] Supplemental Data  

Michael S. Wollenberg and Sanford M. Simon
Signal Sequence Cleavage of Peptidyl-tRNA Prior to Release from the Ribosome and Translocon
J. Biol. Chem. 2004 279: 24919-24922. First Published on April 13, 2004; doi:10.1074/jbc.C400018200 [Abstract] [Full Text] [PDF]  

DNA: Replication, Repair, and Recombination:

Taido Matsui, Yuko Katsuno, Tomoharu Inoue, Fumitaka Fujita, Takashi Joh, Hiroyuki Niida, Hiroshi Murakami, Makoto Itoh, and Makoto Nakanishi
Negative Regulation of Chk2 Expression by p53 Is Dependent on the CCAAT-binding Transcription Factor NF-Y
J. Biol. Chem. 2004 279: 25093-25100. First Published on March 25, 2004; doi:10.1074/jbc.M403232200 [Abstract] [Full Text] [PDF]  

Donny Wong and Bruce Demple
Modulation of the 5'-Deoxyribose-5-phosphate Lyase and DNA Synthesis Activities of Mammalian DNA Polymerase {beta} by Apurinic/Apyrimidinic Endonuclease 1
J. Biol. Chem. 2004 279: 25268-25275. First Published on April 11, 2004; doi:10.1074/jbc.M400804200 [Abstract] [Full Text] [PDF]  

Kiyohiro Ando, Toshinori Ozaki, Hideki Yamamoto, Kazushige Furuya, Mitsuchika Hosoda, Syunji Hayashi, Masahiro Fukuzawa, and Akira Nakagawara
Polo-like Kinase 1 (Plk1) Inhibits p53 Function by Physical Interaction and Phosphorylation
J. Biol. Chem. 2004 279: 25549-25561. First Published on March 15, 2004; doi:10.1074/jbc.M314182200 [Abstract] [Full Text] [PDF]  

Melissa E. Stauffer and Walter J. Chazin
Physical Interaction between Replication Protein A and Rad51 Promotes Exchange on Single-stranded DNA
J. Biol. Chem. 2004 279: 25638-25645. First Published on March 31, 2004; doi:10.1074/jbc.M400029200 [Abstract] [Full Text] [PDF]  

Charles E. Jones, Erin M. Green, Julia A. Stephens, Timothy C. Mueser, and Nancy G. Nossal
Mutations of Bacteriophage T4 59 Helicase Loader Defective in Binding Fork DNA and in Interactions with T4 32 Single-stranded DNA-binding Protein
J. Biol. Chem. 2004 279: 25721-25728. First Published on April 13, 2004; doi:10.1074/jbc.M402128200 [Abstract] [Full Text] [PDF]  

Joaquim Roca
The Path of the DNA along the Dimer Interface of Topoisomerase II
J. Biol. Chem. 2004 279: 25783-25788. First Published on March 27, 2004; doi:10.1074/jbc.M402555200 [Abstract] [Full Text] [PDF]  

Akira Nabetani, Osamu Yokoyama, and Fuyuki Ishikawa
Localization of hRad9, hHus1, hRad1, and hRad17 and Caffeine-sensitive DNA Replication at the Alternative Lengthening of Telomeres-associated Promyelocytic Leukemia Body
J. Biol. Chem. 2004 279: 25849-25857. First Published on April 9, 2004; doi:10.1074/jbc.M312652200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Janice C. Jones, Hemali P. Phatnani, Timothy A. Haystead, Justin A. MacDonald, S. Munir Alam, and Arno L. Greenleaf
C-terminal Repeat Domain Kinase I Phosphorylates Ser2 and Ser5 of RNA Polymerase II C-terminal Domain Repeats
J. Biol. Chem. 2004 279: 24957-24964. First Published on March 26, 2004; doi:10.1074/jbc.M402218200 [Abstract] [Full Text] [PDF]  

Jue-Lon Shie, Guifu Wu, Jiaping Wu, Fen-Fen Liu, Roger J. Laham, Peter Oettgen, and Jian Li
RTEF-1, a Novel Transcriptional Stimulator of Vascular Endothelial Growth Factor in Hypoxic Endothelial Cells
J. Biol. Chem. 2004 279: 25010-25016. First Published on April 8, 2004; doi:10.1074/jbc.M403103200 [Abstract] [Full Text] [PDF]  

Christi Andrin and Michael J. Hendzel
F-actin-dependent Insolubility of Chromatin-modifying Components
J. Biol. Chem. 2004 279: 25017-25023. First Published on April 13, 2004; doi:10.1074/jbc.M401805200 [Abstract] [Full Text] [PDF]  

Anthony I. Vulin and Frederick M. Stanley
Oxidative Stress Activates the Plasminogen Activator Inhibitor Type 1 (PAI-1) Promoter through an AP-1 Response Element and Cooperates with Insulin for Additive Effects on PAI-1 Transcription
J. Biol. Chem. 2004 279: 25172-25178. First Published on April 5, 2004; doi:10.1074/jbc.M403184200 [Abstract] [Full Text] [PDF]  

Hong Wang, Ruihua Fang, Je-Yoel Cho, Towia A. Libermann, and Peter Oettgen
Positive and Negative Modulation of the Transcriptional Activity of the ETS Factor ESE-1 through Interaction with p300, CREB-binding Protein, and Ku 70/86
J. Biol. Chem. 2004 279: 25241-25250. First Published on April 8, 2004; doi:10.1074/jbc.M401356200 [Abstract] [Full Text] [PDF]  

Stephan Fath, Michael S. Kobor, Anja Philippi, Jack Greenblatt, and Herbert Tschochner
Dephosphorylation of RNA Polymerase I by Fcp1p Is Required for Efficient rRNA Synthesis
J. Biol. Chem. 2004 279: 25251-25259. First Published on April 8, 2004; doi:10.1074/jbc.M401867200 [Abstract] [Full Text] [PDF]  

Asmahan Abu-Arish, Daphna Frenkiel-Krispin, Tobin Fricke, Tzvi Tzfira, Vitaly Citovsky, Sharon Grayer Wolf, and Michael Elbaum
Three-dimensional Reconstruction of Agrobacterium VirE2 Protein with Single-stranded DNA
J. Biol. Chem. 2004 279: 25359-25363. First Published on March 30, 2004; doi:10.1074/jbc.M401804200 [Abstract] [Full Text] [PDF]  

Frédérique Magdinier, Timur M. Yusufzai, and Gary Felsenfeld
Both CTCF-dependent and -independent Insulators Are Found between the Mouse T Cell Receptor {alpha} and Dad1 Genes
J. Biol. Chem. 2004 279: 25381-25389. First Published on April 13, 2004; doi:10.1074/jbc.M403121200 [Abstract] [Full Text] [PDF]  

Stella Carro, Anna Bergo, Mauro Mengoni, Angela Bachi, Gianfranco Badaracco, Charlotte Kilstrup-Nielsen, and Nicoletta Landsberger
A Novel Protein, Xenopus p20, Influences the Stability of MeCP2 through Direct Interaction
J. Biol. Chem. 2004 279: 25623-25631. First Published on March 31, 2004; doi:10.1074/jbc.M402571200 [Abstract] [Full Text] [PDF]  

Angamuthu Selvapandiyan, Alain Debrabant, Robert Duncan, Jacqueline Muller, Poonam Salotra, Gannavaram Sreenivas, Jeffrey L. Salisbury, and Hira L. Nakhasi
Centrin Gene Disruption Impairs Stage-specific Basal Body Duplication and Cell Cycle Progression in Leishmania
J. Biol. Chem. 2004 279: 25703-25710. First Published on April 14, 2004; doi:10.1074/jbc.M402794200 [Abstract] [Full Text] [PDF]  

Xavier Le Guezennec, Gert Vriend, and Hendrik G. Stunnenberg
Molecular Determinants of the Interaction of Mad with the PAH2 Domain of mSin3
J. Biol. Chem. 2004 279: 25823-25829. First Published on March 26, 2004; doi:10.1074/jbc.M313860200 [Abstract] [Full Text] [PDF]  

Nang Nguyen, Xiaohong Zhang, Nancy Olashaw, and Edward Seto
Molecular Cloning and Functional Characterization of the Transcription Factor YY2
J. Biol. Chem. 2004 279: 25927-25934. First Published on April 15, 2004; doi:10.1074/jbc.M402525200 [Abstract] [Full Text] [PDF]  

RNA: Structure, Metabolism, and Catalysis:

Claudio Valverde, Magnus Lindell, E. Gerhart H. Wagner, and Dieter Haas
A Repeated GGA Motif Is Critical for the Activity and Stability of the Riboregulator RsmY of Pseudomonas fluorescens
J. Biol. Chem. 2004 279: 25066-25074. First Published on March 18, 2004; doi:10.1074/jbc.M401870200 [Abstract] [Full Text] [PDF]  

Chiharu Shirai, Tomoko Takai, Masanobu Nariai, Chihiro Horigome, and Keiko Mizuta
Ebp2p, the Yeast Homolog of Epstein-Barr Virus Nuclear Antigen 1-binding Protein 2, Interacts with Factors of Both the 60 S and the 40 S Ribosomal Subunit Assembly
J. Biol. Chem. 2004 279: 25353-25358. First Published on April 12, 2004; doi:10.1074/jbc.M403338200 [Abstract] [Full Text] [PDF]  

Romary Perrin, Etienne H. Meyer, Marlyse Zaepfel, Yean-Jung Kim, Régis Mache, Jean-Michel Grienenberger, José M. Gualberto, and Dominique Gagliardi
Two Exoribonucleases Act Sequentially to Process Mature 3'-Ends of atp9 mRNAs in Arabidopsis Mitochondria
J. Biol. Chem. 2004 279: 25440-25446. First Published on March 22, 2004; doi:10.1074/jbc.M401182200 [Abstract] [Full Text] [PDF]  

Yuanyuan Ma, Tetsuro Shimakami, Hong Luo, Naoyuki Hayashi, and Seishi Murakami
Mutational Analysis of Hepatitis C Virus NS5B in the Subgenomic Replicon Cell Culture
J. Biol. Chem. 2004 279: 25474-25482. First Published on March 22, 2004; doi:10.1074/jbc.M401067200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Radim Osicka, Katerina Procházková, Miroslav Sulc, Irena Linhartová, Vladimír Havlícek, and Peter Sebo
A Novel "Clip-and-link" Activity of Repeat in Toxin (RTX) Proteins from Gram-negative Pathogens: COVALENT PROTEIN CROSS-LINKING BY AN ASP-LYS ISOPEPTIDE BOND UPON CALCIUM-DEPENDENT PROCESSING AT AN ASP-PRO BOND
J. Biol. Chem. 2004 279: 24944-24956. First Published on March 24, 2004; doi:10.1074/jbc.M314013200 [Abstract] [Full Text] [PDF]  

David Ghibaudo, Lisette Cohen, François Penin, and Annette Martin
Characterization of GB Virus B Polyprotein Processing Reveals the Existence of a Novel 13-kDa Protein with Partial Homology to Hepatitis C Virus p7 Protein
J. Biol. Chem. 2004 279: 24965-24975. First Published on April 1, 2004; doi:10.1074/jbc.M401148200 [Abstract] [Full Text] [PDF] Supplemental Data  

Xian Zhang, Andrew S. Turnell, Carlos Gorbea, Joe S. Mymryk, Phillip H. Gallimore, and Roger J. A. Grand
The Targeting of the Proteasomal Regulatory Subunit S2 by Adenovirus E1A Causes Inhibition of Proteasomal Activity and Increased p53 Expression
J. Biol. Chem. 2004 279: 25122-25133. First Published on March 31, 2004; doi:10.1074/jbc.M403287200 [Abstract] [Full Text] [PDF]  

Nadeem Wajih, David C. Sane, Susan M. Hutson, and Reidar Wallin
The Inhibitory Effect of Calumenin on the Vitamin K-dependent {gamma}-Carboxylation System: CHARACTERIZATION OF THE SYSTEM IN NORMAL AND WARFARIN-RESISTANT RATS
J. Biol. Chem. 2004 279: 25276-25283. First Published on April 9, 2004; doi:10.1074/jbc.M401645200 [Abstract] [Full Text] [PDF]  

Jeesun Kim, Jaeho Lee, Neelu Yadav, Qi Wu, Carla Carter, Stéphane Richard, Ellen Richie, and Mark T. Bedford
Loss of CARM1 Results in Hypomethylation of Thymocyte Cyclic AMP-regulated Phosphoprotein and Deregulated Early T Cell Development
J. Biol. Chem. 2004 279: 25339-25344. First Published on April 19, 2004; doi:10.1074/jbc.M402544200 [Abstract] [Full Text] [PDF]  

Jochen Klucken, Youngah Shin, Eliezer Masliah, Bradley T. Hyman, and Pamela J. McLean
Hsp70 Reduces {alpha}-Synuclein Aggregation and Toxicity
J. Biol. Chem. 2004 279: 25497-25502. First Published on March 25, 2004; doi:10.1074/jbc.M400255200 [Abstract] [Full Text] [PDF]  

Thalia Nittis and Jonathan D. Gitlin
Role of Copper in the Proteosome-mediated Degradation of the Multicopper Oxidase Hephaestin
J. Biol. Chem. 2004 279: 25696-25702. First Published on April 15, 2004; doi:10.1074/jbc.M401151200 [Abstract] [Full Text] [PDF]  

Matthew W. Foster and Jonathan S. Stamler
New Insights into Protein S-Nitrosylation: MITOCHONDRIA AS A MODEL SYSTEM
J. Biol. Chem. 2004 279: 25891-25897. First Published on April 6, 2004; doi:10.1074/jbc.M313853200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Zongmin Zhou, Steffen Gross, Charis Roussos, Sabine Meurer, Werner Müller-Esterl, and Andreas Papapetropoulos
Structural and Functional Characterization of the Dimerization Region of Soluble Guanylyl Cyclase
J. Biol. Chem. 2004 279: 24935-24943. First Published on March 22, 2004; doi:10.1074/jbc.M402105200 [Abstract] [Full Text] [PDF]  

Heike Eberl, Peter Tittmann, and Rudi Glockshuber
Characterization of Recombinant, Membrane-attached Full-length Prion Protein
J. Biol. Chem. 2004 279: 25058-25065. First Published on March 18, 2004; doi:10.1074/jbc.M400952200 [Abstract] [Full Text] [PDF]  

Pamela A. Wearsch, Claude A. Jakob, Antonio Vallin, Raymond A. Dwek, Pauline M. Rudd, and Peter Cresswell
Major Histocompatibility Complex Class I Molecules Expressed with Monoglucosylated N-Linked Glycans Bind Calreticulin Independently of Their Assembly Status
J. Biol. Chem. 2004 279: 25112-25121. First Published on March 31, 2004; doi:10.1074/jbc.M401721200 [Abstract] [Full Text] [PDF]  

Angela Valeva, Ivan Walev, Silvia Weis, Fatima Boukhallouk, Trudy M. Wassenaar, Kristina Endres, Falk Fahrenholz, Sucharit Bhakdi, and Alexander Zitzer
A Cellular Metalloproteinase Activates Vibrio cholerae Pro-cytolysin
J. Biol. Chem. 2004 279: 25143-25148. First Published on April 5, 2004; doi:10.1074/jbc.M313913200 [Abstract] [Full Text] [PDF]  

Young Gerl Ma, Mi Yhang Cho, Mingyi Zhao, Ji Won Park, Misao Matsushita, Teizo Fujita, and Bok Luel Lee
Human Mannose-binding Lectin and L-Ficolin Function as Specific Pattern Recognition Proteins in the Lectin Activation Pathway of Complement
J. Biol. Chem. 2004 279: 25307-25312. First Published on April 12, 2004; doi:10.1074/jbc.M400701200 [Abstract] [Full Text] [PDF]  

Kaouther Ajroud, Takashi Sugimori, Wolfgang H. Goldmann, Dahmani M. Fathallah, Jian-Ping Xiong, and M. Amin Arnaout
Binding Affinity of Metal Ions to the CD11b A-domain Is Regulated by Integrin Activation and Ligands
J. Biol. Chem. 2004 279: 25483-25488. First Published on April 7, 2004; doi:10.1074/jbc.M402901200 [Abstract] [Full Text] [PDF]  

Qin Xu, Walter J. Brecht, Karl H. Weisgraber, Robert W. Mahley, and Yadong Huang
Apolipoprotein E4 Domain Interaction Occurs in Living Neuronal Cells as Determined by Fluorescence Resonance Energy Transfer
J. Biol. Chem. 2004 279: 25511-25516. First Published on March 30, 2004; doi:10.1074/jbc.M311256200 [Abstract] [Full Text] [PDF]  

Fernando M. V. Dias, Florence Vincent, Gavin Pell, José A. M. Prates, Maria S. J. Centeno, Louise E. Tailford, Luís M. A. Ferreira, Carlos M. G. A. Fontes, Gideon J. Davies, and Harry J. Gilbert
Insights into the Molecular Determinants of Substrate Specificity in Glycoside Hydrolase Family 5 Revealed by the Crystal Structure and Kinetics of Cellvibrio mixtus Mannosidase 5A
J. Biol. Chem. 2004 279: 25517-25526. First Published on March 10, 2004; doi:10.1074/jbc.M401647200 [Abstract] [Full Text] [PDF]  

Scott F. Cummins, Amy E. Nichols, Andinet Amare, Amanda B. Hummon, Jonathan V. Sweedler, and Gregg T. Nagle
Characterization of Aplysia Enticin and Temptin, Two Novel Water-borne Protein Pheromones That Act in Concert with Attractin to Stimulate Mate Attraction
J. Biol. Chem. 2004 279: 25614-25622. First Published on March 30, 2004; doi:10.1074/jbc.M313585200 [Abstract] [Full Text] [PDF] Supplemental Data  

Norelle L. Daly, Jenny A. Ekberg, Linda Thomas, David J. Adams, Richard J. Lewis, and David J. Craik
Structures of µO-conotoxins from Conus marmoreus: INHIBITORS OF TETRODOTOXIN (TTX)-SENSITIVE AND TTX-RESISTANT SODIUM CHANNELS IN MAMMALIAN SENSORY NEURONS
J. Biol. Chem. 2004 279: 25774-25782. First Published on March 24, 2004; doi:10.1074/jbc.M313002200 [Abstract] [Full Text] [PDF] Supplemental Data  

Cécile Meunier-Jamin, Ulrike Kapp, Gordon A. Leonard, and Seán McSweeney
The Structure of the Organic Hydroperoxide Resistance Protein from Deinococcus radiodurans: DO CONFORMATIONAL CHANGES FACILITATE RECYCLING OF THE REDOX DISULFIDE?
J. Biol. Chem. 2004 279: 25830-25837. First Published on March 30, 2004; doi:10.1074/jbc.M312983200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Irina Y. Sazonova, Brian R. Robinson, Inna P. Gladysheva, Francis J. Castellino, and Guy L. Reed
{alpha} Domain Deletion Converts Streptokinase into a Fibrin-dependent Plasminogen Activator through Mechanisms Akin to Staphylokinase and Tissue Plasminogen Activator
J. Biol. Chem. 2004 279: 24994-25001. First Published on April 6, 2004; doi:10.1074/jbc.M400253200 [Abstract] [Full Text] [PDF]  

Stefan Malonek, Maria C. Rojas, Peter Hedden, Paul Gaskin, Paul Hopkins, and Bettina Tudzynski
The NADPH-cytochrome P450 Reductase Gene from Gibberella fujikuroi Is Essential for Gibberellin Biosynthesis
J. Biol. Chem. 2004 279: 25075-25084. First Published on March 22, 2004; doi:10.1074/jbc.M308517200 [Abstract] [Full Text] [PDF]  

Didier Pitsi and Jean-Noël Octave
Presenilin 1 Stabilizes the C-terminal Fragment of the Amyloid Precursor Protein Independently of {gamma}-Secretase Activity
J. Biol. Chem. 2004 279: 25333-25338. First Published on April 15, 2004; doi:10.1074/jbc.M312710200 [Abstract] [Full Text] [PDF]  

Ying-Zi Ge, Min-Tie Pu, Humaira Gowher, Hai-Ping Wu, Jian-Ping Ding, Albert Jeltsch, and Guo-Liang Xu
Chromatin Targeting of de Novo DNA Methyltransferases by the PWWP Domain
J. Biol. Chem. 2004 279: 25447-25454. First Published on March 3, 2004; doi:10.1074/jbc.M312296200 [Abstract] [Full Text] [PDF]  

Jérôme Deval, Jean-Marc Navarro, Boulbaba Selmi, Jérôme Courcambeck, Joëlle Boretto, Philippe Halfon, Sarah Garrido-Urbani, Josephine Sire, and Bruno Canard
A Loss of Viral Replicative Capacity Correlates with Altered DNA Polymerization Kinetics by the Human Immunodeficiency Virus Reverse Transcriptase Bearing the K65R and L74V Dideoxynucleoside Resistance Substitutions
J. Biol. Chem. 2004 279: 25489-25496. First Published on March 23, 2004; doi:10.1074/jbc.M313534200 [Abstract] [Full Text] [PDF]  

Stephanie A. Smith and F. Robert Tabita
Glycine 176 Affects Catalytic Properties and Stability of the Synechococcus sp. Strain PCC6301 Ribulose-1,5-bisphosphate Carboxylase/Oxygenase
J. Biol. Chem. 2004 279: 25632-25637. First Published on April 2, 2004; doi:10.1074/jbc.M401360200 [Abstract] [Full Text] [PDF]  

Matthew C. Posewitz, Paul W. King, Sharon L. Smolinski, Liping Zhang, Michael Seibert, and Maria L. Ghirardi
Discovery of Two Novel Radical S-Adenosylmethionine Proteins Required for the Assembly of an Active [Fe] Hydrogenase
J. Biol. Chem. 2004 279: 25711-25720. First Published on April 13, 2004; doi:10.1074/jbc.M403206200 [Abstract] [Full Text] [PDF]  

Xiao-Ying Cui, Qi-Dong Hu, Meriem Tekaya, Yasushi Shimoda, Beng-Ti Ang, Du-Yu Nie, Li Sun, Wei-Ping Hu, Meliha Karsak, Tanya Duka, Yasuo Takeda, Lian-Yun Ou, Gavin S. Dawe, Feng-Gang Yu, Sohail Ahmed, Lian-Hong Jin, Melitta Schachner, Kazutada Watanabe, Yvan Arsenijevic, and Zhi-Cheng Xiao
NB-3/Notch1 Pathway via Deltex1 Promotes Neural Progenitor Cell Differentiation into Oligodendrocytes
J. Biol. Chem. 2004 279: 25858-25865. First Published on April 12, 2004; doi:10.1074/jbc.M313505200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Olivier Roger, Régis Lavigne, Mohamed Mahmoud, Corinne Buisson, Bernard Onno, Ben-Li Zhang, and Richard J. Robins
Quantitative 2H NMR at Natural Abundance Can Distinguish the Pathway Used for Glucose Fermentation by Lactic Acid Bacteria
J. Biol. Chem. 2004 279: 24923-24928. First Published on March 29, 2004; doi:10.1074/jbc.M401232200 [Abstract] [Full Text] [PDF]  

Jee-Youn Ryu, Ji Young Song, Jeong Mi Lee, Suk Won Jeong, Wah Soon Chow, Sang-Bong Choi, Barry J. Pogson, and Youn-Il Park
Glucose-induced Expression of Carotenoid Biosynthesis Genes in the Dark Is Mediated by Cytosolic pH in the Cyanobacterium Synechocystis sp. PCC 6803
J. Biol. Chem. 2004 279: 25320-25325. First Published on April 12, 2004; doi:10.1074/jbc.M402541200 [Abstract] [Full Text] [PDF]  

Kyoung-Seok Ryu, Changhoon Kim, Insook Kim, Seokho Yoo, Byong-Seok Choi, and Chankyu Park
NMR Application Probes a Novel and Ubiquitous Family of Enzymes That Alter Monosaccharide Configuration
J. Biol. Chem. 2004 279: 25544-25548. First Published on April 1, 2004; doi:10.1074/jbc.M402016200 [Abstract] [Full Text] [PDF] Supplemental Data  

Joachim Weber, Alma Muharemagic, Susan Wilke-Mounts, and Alan E. Senior
Analysis of Sequence Determinants of F1Fo-ATP Synthase in the N-terminal Region of {alpha} Subunit for Binding of {delta} Subunit
J. Biol. Chem. 2004 279: 25673-25679. First Published on April 6, 2004; doi:10.1074/jbc.M402738200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Henning H. Mann, Suat Özbek, Jürgen Engel, Mats Paulsson, and Raimund Wagener
Interactions between the Cartilage Oligomeric Matrix Protein and Matrilins: IMPLICATIONS FOR MATRIX ASSEMBLY AND THE PATHOGENESIS OF CHONDRODYSPLASIAS
J. Biol. Chem. 2004 279: 25294-25298. First Published on April 9, 2004; doi:10.1074/jbc.M403778200 [Abstract] [Full Text] [PDF]  

Takafumi Ito, John D. Williams, Donald J. Fraser, and Aled O. Phillips
Hyaluronan Regulates Transforming Growth Factor-{beta}1 Receptor Compartmentalization
J. Biol. Chem. 2004 279: 25326-25332. First Published on April 14, 2004; doi:10.1074/jbc.M403135200 [Abstract] [Full Text] [PDF]  

Wei Zou, Silvia Borrelli, Michel Gilbert, Tianmin Liu, Robert A. Pon, and Harold J. Jennings
Bioengineering of Surface GD3 Ganglioside for Immunotargeting Human Melanoma Cells
J. Biol. Chem. 2004 279: 25390-25399. First Published on March 26, 2004; doi:10.1074/jbc.M402787200 [Abstract] [Full Text] [PDF]  

Jeff P. Gorski, Aimin Wang, Dinah Lovitch, Douglas Law, Kimerly Powell, and Ronald J. Midura
Extracellular Bone Acidic Glycoprotein-75 Defines Condensed Mesenchyme Regions to be Mineralized and Localizes with Bone Sialoprotein during Intramembranous Bone Formation
J. Biol. Chem. 2004 279: 25455-25463. First Published on March 5, 2004; doi:10.1074/jbc.M312408200 [Abstract] [Full Text] [PDF]  

Ronald J. Midura, Aimin Wang, Dinah Lovitch, Douglas Law, Kimerly Powell, and Jeff P. Gorski
Bone Acidic Glycoprotein-75 Delineates the Extracellular Sites of Future Bone Sialoprotein Accumulation and Apatite Nucleation in Osteoblastic Cultures
J. Biol. Chem. 2004 279: 25464-25473. First Published on March 5, 2004; doi:10.1074/jbc.M312409200 [Abstract] [Full Text] [PDF]  

Jun-Hyeog Jang, Jung-Hee Hwang, Chong-Pyoung Chung, and Pill-Hoon Choung
Identification and Kinetics Analysis of a Novel Heparin-binding Site (KEDK) in Human Tenascin-C
J. Biol. Chem. 2004 279: 25562-25566. First Published on April 6, 2004; doi:10.1074/jbc.M403170200 [Abstract] [Full Text] [PDF]  

Amaya Puig-Kröger, Diego Serrano-Gómez, Esther Caparrós, Angeles Domínguez-Soto, Miguel Relloso, María Colmenares, Laura Martínez-Muñoz, Natividad Longo, Noelia Sánchez-Sánchez, Mercedes Rincon, Luis Rivas, Paloma Sánchez-Mateos, Elena Fernández-Ruiz, and Angel L. Corbí
Regulated Expression of the Pathogen Receptor Dendritic Cell-specific Intercellular Adhesion Molecule 3 (ICAM-3)-grabbing Nonintegrin in THP-1 Human Leukemic Cells, Monocytes, and Macrophages
J. Biol. Chem. 2004 279: 25680-25688. First Published on April 7, 2004; doi:10.1074/jbc.M311516200 [Abstract] [Full Text] [PDF]  

Jayne Lesley, István Gál, David J. Mahoney, Martin R. Cordell, Marilyn S. Rugg, Robert Hyman, Anthony J. Day, and Katalin Mikecz
TSG-6 Modulates the Interaction between Hyaluronan and Cell Surface CD44
J. Biol. Chem. 2004 279: 25745-25754. First Published on April 1, 2004; doi:10.1074/jbc.M313319200 [Abstract] [Full Text] [PDF] Supplemental Data  

Suzanne C. Edavettal, Karen A. Lee, Masahiko Negishi, Robert J. Linhardt, Jian Liu, and Lars C. Pedersen
Crystal Structure and Mutational Analysis of Heparan Sulfate 3-O-Sulfotransferase Isoform 1
J. Biol. Chem. 2004 279: 25789-25797. First Published on April 1, 2004; doi:10.1074/jbc.M401089200 [Abstract] [Full Text] [PDF]  

Kiyohiko Angata, Dominic Chan, Joseph Thibault, and Minoru Fukuda
Molecular Dissection of the ST8Sia IV Polysialyltransferase: DISTINCT DOMAINS ARE REQUIRED FOR NEURAL CELL ADHESION MOLECULE RECOGNITION AND POLYSIALYLATION
J. Biol. Chem. 2004 279: 25883-25890. First Published on April 2, 2004; doi:10.1074/jbc.M401562200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Saj Parathath, Daisy Sahoo, Yolanda F. Darlington, Yinan Peng, Heidi L. Collins, George H. Rothblat, David L. Williams, and Margery A. Connelly
Glycine 420 Near the C-terminal Transmembrane Domain of SR-BI Is Critical for Proper Delivery and Metabolism of High Density Lipoprotein Cholesteryl Ester
J. Biol. Chem. 2004 279: 24976-24985. First Published on April 1, 2004; doi:10.1074/jbc.M402435200 [Abstract] [Full Text] [PDF]  

Ayanna Augustus, Hiroaki Yagyu, Guenter Haemmerle, André Bensadoun, Reeba K. Vikramadithyan, So-Young Park, Jason K. Kim, Rudolf Zechner, and Ira J. Goldberg
Cardiac-specific Knock-out of Lipoprotein Lipase Alters Plasma Lipoprotein Triglyceride Metabolism and Cardiac Gene Expression
J. Biol. Chem. 2004 279: 25050-25057. First Published on March 17, 2004; doi:10.1074/jbc.M401028200 [Abstract] [Full Text] [PDF]  

Norma Marchesini, Walid Osta, Jacek Bielawski, Chiara Luberto, Lina M. Obeid, and Yusuf A. Hannun
Role for Mammalian Neutral Sphingomyelinase 2 in Confluence-induced Growth Arrest of MCF7 Cells
J. Biol. Chem. 2004 279: 25101-25111. First Published on March 29, 2004; doi:10.1074/jbc.M313662200 [Abstract] [Full Text] [PDF]  

Makoto Miyazaki, Agnieszka Dobrzyn, Weng Chi Man, Kiki Chu, Harini Sampath, Hyoun-Ju Kim, and James M. Ntambi
Stearoyl-CoA Desaturase 1 Gene Expression Is Necessary for Fructose-mediated Induction of Lipogenic Gene Expression by Sterol Regulatory Element-binding Protein-1c-dependent and -independent Mechanisms
J. Biol. Chem. 2004 279: 25164-25171. First Published on April 5, 2004; doi:10.1074/jbc.M402781200 [Abstract] [Full Text] [PDF]  

Charles R. Sweet, Anthony A. Ribeiro, and Christian R. H. Raetz
Oxidation and Transamination of the 3''-Position of UDP-N-Acetylglucosamine by Enzymes from Acidithiobacillus ferrooxidans: ROLE IN THE FORMATION OF LIPID A MOLECULES WITH FOUR AMIDE-LINKED ACYL CHAINS
J. Biol. Chem. 2004 279: 25400-25410. First Published on March 24, 2004; doi:10.1074/jbc.M400596200 [Abstract] [Full Text] [PDF] Supplemental Data  

Charles R. Sweet, Allison H. Williams, Mark J. Karbarz, Catherine Werts, Suzanne R. Kalb, Robert J. Cotter, and Christian R. H. Raetz
Enzymatic Synthesis of Lipid A Molecules with Four Amide-linked Acyl Chains: LpxA ACYLTRANSFERASES SELECTIVE FOR AN ANALOG OF UDP-N-ACETYLGLUCOSAMINE IN WHICH AN AMINE REPLACES THE 3''-HYDROXYL GROUP
J. Biol. Chem. 2004 279: 25411-25419. First Published on March 24, 2004; doi:10.1074/jbc.M400597200 [Abstract] [Full Text] [PDF]  

Nanette L. S. Que-Gewirth, Anthony A. Ribeiro, Suzanne R. Kalb, Robert J. Cotter, Dieter M. Bulach, Ben Adler, Isabelle Saint Girons, Catherine Werts, and Christian R. H. Raetz
A Methylated Phosphate Group and Four Amide-linked Acyl Chains in Leptospira interrogans Lipid A: THE MEMBRANE ANCHOR OF AN UNUSUAL LIPOPOLYSACCHARIDE THAT ACTIVATES TLR2
J. Biol. Chem. 2004 279: 25420-25429. First Published on March 24, 2004; doi:10.1074/jbc.M400598200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Lubna Al-Khalili, Olga Kotova, Hiroki Tsuchida, Ingrid Ehrén, Eric Féraille, Anna Krook, and Alexander V. Chibalin
ERK1/2 Mediates Insulin Stimulation of Na,K-ATPase by Phosphorylation of the {alpha}-Subunit in Human Skeletal Muscle Cells
J. Biol. Chem. 2004 279: 25211-25218. First Published on April 6, 2004; doi:10.1074/jbc.M402152200 [Abstract] [Full Text] [PDF]  

Raz Palty, Ehud Ohana, Michal Hershfinkel, Micha Volokita, Vered Elgazar, Ofer Beharier, William F. Silverman, Miriam Argaman, and Israel Sekler
Lithium-Calcium Exchange Is Mediated by a Distinct Potassium-independent Sodium-Calcium Exchanger
J. Biol. Chem. 2004 279: 25234-25240. First Published on April 1, 2004; doi:10.1074/jbc.M401229200 [Abstract] [Full Text] [PDF]  

Rita Aiello, Angela Messina, Bettina Schiffler, Roland Benz, Gianluca Tasco, Rita Casadio, and Vito De Pinto
Functional Characterization of a Second Porin Isoform in Drosophila melanogaster: DMPORIN2 FORMS VOLTAGE-INDEPENDENT CATION-SELECTIVE PORES
J. Biol. Chem. 2004 279: 25364-25373. First Published on March 30, 2004; doi:10.1074/jbc.M310572200 [Abstract] [Full Text] [PDF]  

Gloria Salazar, Rachal Love, Melanie L. Styers, Erica Werner, Andrew Peden, Sandra Rodriguez, Marla Gearing, Bruce H. Wainer, and Victor Faundez
AP-3-dependent Mechanisms Control the Targeting of a Chloride Channel (ClC-3) in Neuronal and Non-neuronal Cells
J. Biol. Chem. 2004 279: 25430-25439. First Published on April 8, 2004; doi:10.1074/jbc.M402331200 [Abstract] [Full Text] [PDF]  

Ilan Ifergan, Assaf Shafran, Gerrit Jansen, Jan Hendrik Hooijberg, George L. Scheffer, and Yehuda G. Assaraf
Folate Deprivation Results in the Loss of Breast Cancer Resistance Protein (BCRP/ABCG2) Expression: A ROLE FOR BCRP IN CELLULAR FOLATE HOMEOSTASIS
J. Biol. Chem. 2004 279: 25527-25534. First Published on March 26, 2004; doi:10.1074/jbc.M401725200 [Abstract] [Full Text] [PDF]  

Victor Babich, Wei-Zhong Zeng, Byung-Il Yeh, Oxana Ibraghimov-Beskrovnaya, Yiqiang Cai, Stefan Somlo, and Chou-Long Huang
The N-terminal Extracellular Domain Is Required for Polycystin-1-dependent Channel Activity
J. Biol. Chem. 2004 279: 25582-25589. First Published on April 1, 2004; doi:10.1074/jbc.M402829200 [Abstract] [Full Text] [PDF]  

Pasqualina Castaldo, Patrizia Stefanoni, Francesco Miceli, Giangennaro Coppola, Emanuele Miraglia del Giudice, Giulia Bellini, Antonio Pascotto, James R. Trudell, Neil L. Harrison, Lucio Annunziato, and Maurizio Taglialatela
A Novel Hyperekplexia-causing Mutation in the Pre-transmembrane Segment 1 of the Human Glycine Receptor {alpha}1 Subunit Reduces Membrane Expression and Impairs Gating by Agonists
J. Biol. Chem. 2004 279: 25598-25604. First Published on April 5, 2004; doi:10.1074/jbc.M311021200 [Abstract] [Full Text] [PDF] Supplemental Data  

James Jianping Wu and Guido Guidotti
Proreceptor Dimerization Is Required for Insulin Receptor Post-translational Processing
J. Biol. Chem. 2004 279: 25765-25773. First Published on April 9, 2004; doi:10.1074/jbc.M314281200 [Abstract] [Full Text] [PDF]  

Peter J. Mohler, Janis A. Hoffman, Jonathan Q. Davis, Khadar M. Abdi, Chong-Rak Kim, Sarah K. Jones, Lydia H. Davis, Karen F. Roberts, and Vann Bennett
Isoform Specificity among Ankyrins: AN AMPHIPATHIC {alpha}-HELIX IN THE DIVERGENT REGULATORY DOMAIN OF ANKYRIN-B INTERACTS WITH THE MOLECULAR CO-CHAPERONE Hdj1/Hsp40
J. Biol. Chem. 2004 279: 25798-25804. First Published on April 9, 2004; doi:10.1074/jbc.M401296200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Mary L. Standaert, Mini P. Sajan, Atsushi Miura, Yoshinori Kanoh, Hubert C. Chen, Robert V. Farese, Jr., and Robert V. Farese
Insulin-induced Activation of Atypical Protein Kinase C, but Not Protein Kinase B, Is Maintained in Diabetic (ob/ob and Goto-Kakazaki) Liver: CONTRASTING INSULIN SIGNALING PATTERNS IN LIVER VERSUS MUSCLE DEFINE PHENOTYPES OF TYPE 2 DIABETIC AND HIGH FAT-INDUCED INSULIN-RESISTANT STATES
J. Biol. Chem. 2004 279: 24929-24934. First Published on April 6, 2004; doi:10.1074/jbc.M402440200 [Abstract] [Full Text] [PDF]  

Peng Huang, Deborah Steplock, Edward J. Weinman, Randy A. Hall, Zhe Ding, Jianguo Li, Yulin Wang, and Lee-Yuan Liu-Chen
{kappa} Opioid Receptor Interacts with Na+/H+-exchanger Regulatory Factor-1/Ezrin-Radixin-Moesin-binding Phosphoprotein-50 (NHERF-1/EBP50) to Stimulate Na+/H+ Exchange Independent of Gi/Go Proteins
J. Biol. Chem. 2004 279: 25002-25009. First Published on April 7, 2004; doi:10.1074/jbc.M313366200 [Abstract] [Full Text] [PDF]  

Carine M. Mounier, Farideh Ghomashchi, Margaret R. Lindsay, Scott James, Alan G. Singer, Robert G. Parton, and Michael H. Gelb
Arachidonic Acid Release from Mammalian Cells Transfected with Human Groups IIA and X Secreted Phospholipase A2 Occurs Predominantly during the Secretory Process and with the Involvement of Cytosolic Phospholipase A2-{alpha}
J. Biol. Chem. 2004 279: 25024-25038. First Published on March 8, 2004; doi:10.1074/jbc.M313019200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ryo Suzuki, Kazuyuki Tobe, Masashi Aoyama, Atsushi Inoue, Kentaro Sakamoto, Toshimasa Yamauchi, Junji Kamon, Naoto Kubota, Yasuo Terauchi, Hironobu Yoshimatsu, Munehide Matsuhisa, Shoichiro Nagasaka, Hitomi Ogata, Kumpei Tokuyama, Ryozo Nagai, and Takashi Kadowaki
Both Insulin Signaling Defects in the Liver and Obesity Contribute to Insulin Resistance and Cause Diabetes in Irs2–/– Mice
J. Biol. Chem. 2004 279: 25039-25049. First Published on March 17, 2004; doi:10.1074/jbc.M311956200 [Abstract] [Full Text] [PDF]  

Peter Schotte, Geertrui Denecker, Aeke Van Den Broeke, Peter Vandenabeele, Guy R. Cornelis, and Rudi Beyaert
Targeting Rac1 by the Yersinia Effector Protein YopE Inhibits Caspase-1-mediated Maturation and Release of Interleukin-1{beta}
J. Biol. Chem. 2004 279: 25134-25142. First Published on April 1, 2004; doi:10.1074/jbc.M401245200 [Abstract] [Full Text] [PDF]  

Kirsty A. Green, Matthew J. Naylor, Emma T. Lowe, Pengbo Wang, Emma Marshman, and Charles H. Streuli
Caspase-mediated Cleavage of Insulin Receptor Substrate
J. Biol. Chem. 2004 279: 25149-25156. First Published on April 5, 2004; doi:10.1074/jbc.M402395200 [Abstract] [Full Text] [PDF]  

Klaus Moeschel, Alexander Beck, Cora Weigert, Reiner Lammers, Hubert Kalbacher, Wolfgang Voelter, Erwin D. Schleicher, Hans-Ulrich Häring, and Rainer Lehmann
Protein Kinase C-{zeta}-induced Phosphorylation of Ser318 in Insulin Receptor Substrate-1 (IRS-1) Attenuates the Interaction with the Insulin Receptor and the Tyrosine Phosphorylation of IRS-1
J. Biol. Chem. 2004 279: 25157-25163. First Published on April 5, 2004; doi:10.1074/jbc.M402477200 [Abstract] [Full Text] [PDF]  

Sang Hoon Rhee, Andrew C. Keates, Mary P. Moyer, and Charalabos Pothoulakis
MEK Is a Key Modulator for TLR5-induced Interleukin-8 and MIP3{alpha} Gene Expression in Non-transformed Human Colonic Epithelial Cells
J. Biol. Chem. 2004 279: 25179-25188. First Published on April 6, 2004; doi:10.1074/jbc.M400967200 [Abstract] [Full Text] [PDF]  

Sanaâ Noubir, Zakaria Hmama, and Neil E. Reiner
Dual Receptors and Distinct Pathways Mediate Interleukin-1 Receptor-associated Kinase Degradation in Response to Lipopolysaccharide: INVOLVEMENT OF CD14/TLR4, CR3, AND PHOSPHATIDYLINOSITOL 3-KINASE
J. Biol. Chem. 2004 279: 25189-25195. First Published on April 6, 2004; doi:10.1074/jbc.M312431200 [Abstract] [Full Text] [PDF]  

Yuling Wang, Maria Grazia Malabarba, Zsuzsanna S. Nagy, and Robert A. Kirken
Interleukin 4 Regulates Phosphorylation of Serine 756 in the Transactivation Domain of Stat6: ROLES FOR MULTIPLE PHOSPHORYLATION SITES AND Stat6 FUNCTION
J. Biol. Chem. 2004 279: 25196-25203. First Published on April 6, 2004; doi:10.1074/jbc.M313668200 [Abstract] [Full Text] [PDF]  

Daniele Penzo, Valeria Petronilli, Alessia Angelin, Claudia Cusan, Raffaele Colonna, Luca Scorrano, Francesco Pagano, Maurizio Prato, Fabio Di Lisa, and Paolo Bernardi
Arachidonic Acid Released by Phospholipase A2 Activation Triggers Ca2+-dependent Apoptosis through the Mitochondrial Pathway
J. Biol. Chem. 2004 279: 25219-25225. First Published on April 7, 2004; doi:10.1074/jbc.M310381200 [Abstract] [Full Text] [PDF]  

Patricia A. Solski, Rhonda S. Wilder, Kent L. Rossman, John Sondek, Adrienne D. Cox, Sharon L. Campbell, and Channing J. Der
Requirement For C-terminal Sequences in Regulation of Ect2 Guanine Nucleotide Exchange Specificity and Transformation
J. Biol. Chem. 2004 279: 25226-25233. First Published on April 8, 2004; doi:10.1074/jbc.M313792200 [Abstract] [Full Text] [PDF]  

Pengfei Li, Chunrong Li, Xiuhua Zhao, Xiaohong Zhang, Santo V. Nicosia, and Wenlong Bai
p27Kip1 Stabilization and G1 Arrest by 1,25-Dihydroxyvitamin D3 in Ovarian Cancer Cells Mediated through Down-regulation of Cyclin E/Cyclin-dependent Kinase 2 and Skp1-Cullin-F-box Protein/Skp2 Ubiquitin Ligase
J. Biol. Chem. 2004 279: 25260-25267. First Published on April 9, 2004; doi:10.1074/jbc.M311052200 [Abstract] [Full Text] [PDF]  

Kyle A. Murphy, Caren M. Villano, Ruth Dorn, and Lori A. White
Interaction between the Aryl Hydrocarbon Receptor and Retinoic Acid Pathways Increases Matrix Metalloproteinase-1 Expression in Keratinocytes
J. Biol. Chem. 2004 279: 25284-25293. First Published on April 9, 2004; doi:10.1074/jbc.M402168200 [Abstract] [Full Text] [PDF]  

Paolo Lova, Francesca Campus, Rossana Lombardi, Marco Cattaneo, Fabiola Sinigaglia, Cesare Balduini, and Mauro Torti
Contribution of Protease-activated Receptors 1 and 4 and Glycoprotein Ib-IX-V in the Gi-independent Activation of Platelet Rap1B by Thrombin
J. Biol. Chem. 2004 279: 25299-25306. First Published on April 12, 2004; doi:10.1074/jbc.M313199200 [Abstract] [Full Text] [PDF]  

Neetu Kalra and Vijay Kumar
c-Fos Is a Mediator of the c-Myc-induced Apoptotic Signaling in Serum-deprived Hepatoma Cells via the p38 Mitogen-activated Protein Kinase Pathway
J. Biol. Chem. 2004 279: 25313-25319. First Published on April 12, 2004; doi:10.1074/jbc.M400932200 [Abstract] [Full Text] [PDF]  

Simrit Parmar, Efstratios Katsoulidis, Amit Verma, Yongzhong Li, Antonella Sassano, Lakhvir Lal, Beata Majchrzak, Farhad Ravandi, Martin S. Tallman, Eleanor N. Fish, and Leonidas C. Platanias
Role of the p38 Mitogen-activated Protein Kinase Pathway in the Generation of the Effects of Imatinib Mesylate (STI571) in BCR-ABL-expressing Cells
J. Biol. Chem. 2004 279: 25345-25352. First Published on March 31, 2004; doi:10.1074/jbc.M400590200 [Abstract] [Full Text] [PDF]  

Dawang Zhou, Cristiana Noviello, Chiara D'Ambrosio, Andrea Scaloni, and Luciano D'Adamio
Growth Factor Receptor-bound Protein 2 Interaction with the Tyrosine-phosphorylated Tail of Amyloid {beta} Precursor Protein Is Mediated by Its Src Homology 2 Domain
J. Biol. Chem. 2004 279: 25374-25380. First Published on March 30, 2004; doi:10.1074/jbc.M400488200 [Abstract] [Full Text] [PDF]  

Ch. V. Rao, X. Li, S. K. Manna, Z. M. Lei, and B. B. Aggarwal
Human Chorionic Gonadotropin Decreases Proliferation and Invasion of Breast Cancer MCF-7 Cells by Inhibiting NF-{kappa}B and AP-1 Activation
J. Biol. Chem. 2004 279: 25503-25510. First Published on March 24, 2004; doi:10.1074/jbc.M400683200 [Abstract] [Full Text] [PDF]  

Suwei Wang, Eugene A. Konorev, Srigiridhar Kotamraju, Joy Joseph, Shasi Kalivendi, and B. Kalyanaraman
Doxorubicin Induces Apoptosis in Normal and Tumor Cells via Distinctly Different Mechanisms: INTERMEDIACY OF H2O2- AND p53-DEPENDENT PATHWAYS
J. Biol. Chem. 2004 279: 25535-25543. First Published on March 30, 2004; doi:10.1074/jbc.M400944200 [Abstract] [Full Text] [PDF]  

Emanuela Galliera, Venkatakrishna R. Jala, John O. Trent, Raffaella Bonecchi, Paola Signorelli, Robert J. Lefkowitz, Alberto Mantovani, Massimo Locati, and Bodduluri Haribabu
{beta}-Arrestin-dependent Constitutive Internalization of the Human Chemokine Decoy Receptor D6
J. Biol. Chem. 2004 279: 25590-25597. First Published on April 13, 2004; doi:10.1074/jbc.M400363200 [Abstract] [Full Text] [PDF]  

Maria C. Birchenall-Roberts, Tao Fu, Ok-sun Bang, Michael Dambach, James H. Resau, Cari L. Sadowski, Daniel C. Bertolette, Ho-Jae Lee, Seong-Jin Kim, and Francis W. Ruscetti
Tuberous Sclerosis Complex 2 Gene Product Interacts with Human SMAD Proteins: A MOLECULAR LINK OF TWO TUMOR SUPPRESSOR PATHWAYS
J. Biol. Chem. 2004 279: 25605-25613. First Published on April 2, 2004; doi:10.1074/jbc.M402790200 [Abstract] [Full Text] [PDF]  

Allan F. Fierro, Georjeana A. Wurth, and Adam Zweifach
Cross-talk with Ca2+ Influx Does Not Underlie the Role of Extracellular Signal-regulated Kinases in Cytotoxic T Lymphocyte Lytic Granule Exocytosis
J. Biol. Chem. 2004 279: 25646-25652. First Published on April 1, 2004; doi:10.1074/jbc.M400296200 [Abstract] [Full Text] [PDF]  

Cruz Morenilla-Palao, Rosa Planells-Cases, Nuria García-Sanz, and Antonio Ferrer-Montiel
Regulated Exocytosis Contributes to Protein Kinase C Potentiation of Vanilloid Receptor Activity
J. Biol. Chem. 2004 279: 25665-25672. First Published on April 5, 2004; doi:10.1074/jbc.M311515200 [Abstract] [Full Text] [PDF] Supplemental Data  

Francesca Orsini, Enrica Migliaccio, Maurizio Moroni, Cristina Contursi, Veronica A. Raker, Daniele Piccini, Ines Martin-Padura, Giovanni Pelliccia, Mirella Trinei, Maria Bono, Claudia Puri, Carlo Tacchetti, Monica Ferrini, Roberta Mannucci, Ildo Nicoletti, Luisa Lanfrancone, Marco Giorgio, and Pier Giuseppe Pelicci
The Life Span Determinant p66Shc Localizes to Mitochondria Where It Associates with Mitochondrial Heat Shock Protein 70 and Regulates Trans-membrane Potential
J. Biol. Chem. 2004 279: 25689-25695. First Published on April 12, 2004; doi:10.1074/jbc.M401844200 [Abstract] [Full Text] [PDF]  

Maria Filippova, Lindsey Parkhurst, and Penelope J. Duerksen-Hughes
The Human Papillomavirus 16 E6 Protein Binds to Fas-associated Death Domain and Protects Cells from Fas-triggered Apoptosis
J. Biol. Chem. 2004 279: 25729-25744. First Published on April 8, 2004; doi:10.1074/jbc.M401172200 [Abstract] [Full Text] [PDF]  

Siang-Yo Lin, Shital Raval, Zhiyong Zhang, Michele Deverill, Katherine A. Siminovitch, Donald R. Branch, and Beatrice Haimovich
The Protein-tyrosine Phosphatase SHP-1 Regulates the Phosphorylation of {alpha}-Actinin
J. Biol. Chem. 2004 279: 25755-25764. First Published on April 7, 2004; doi:10.1074/jbc.M314175200 [Abstract] [Full Text] [PDF]  

Shivendra V. Singh, Anna Herman-Antosiewicz, Ajita V. Singh, Karen L. Lew, Sanjay K. Srivastava, Ravindra Kamath, Kevin D. Brown, Lin Zhang, and Rajasekaran Baskaran
Sulforaphane-induced G2/M Phase Cell Cycle Arrest Involves Checkpoint Kinase 2-mediated Phosphorylation of Cell Division Cycle 25C
J. Biol. Chem. 2004 279: 25813-25822. First Published on April 8, 2004; doi:10.1074/jbc.M313538200 [Abstract] [Full Text] [PDF]  

Mikyung Kim, Hailin Yang, Sung-Kwon Kim, Pedro A. Reche, Rebecca S. Tirabassi, Rebecca E. Hussey, Yasmin Chishti, James G. Rheinwald, Tiara J. Morehead, Tobias Zech, Inger K. Damon, Raymond M. Welsh, and Ellis L. Reinherz
Biochemical and Functional Analysis of Smallpox Growth Factor (SPGF) and Anti-SPGF Monoclonal Antibodies
J. Biol. Chem. 2004 279: 25838-25848. First Published on April 7, 2004; doi:10.1074/jbc.M400343200 [Abstract] [Full Text] [PDF] Supplemental Data  

Chuan-Min Chen, Yusong Gong, Min Zhang, and Jian-Jun Chen
Reciprocal Cross-talk between Nod2 and TAK1 Signaling Pathways
J. Biol. Chem. 2004 279: 25876-25882. First Published on April 9, 2004; doi:10.1074/jbc.M400682200 [Abstract] [Full Text] [PDF]  

Yuka Toyoshima, Michael Karas, Shoshana Yakar, Joelle Dupont, Lee Helman, and Derek LeRoith
TDAG51 Mediates the Effects of Insulin-like Growth Factor I (IGF-I) on Cell Survival
J. Biol. Chem. 2004 279: 25898-25904. First Published on March 22, 2004; doi:10.1074/jbc.M400661200 [Abstract] [Full Text] [PDF]  

Claudia Champagne, Marie-Claude Landry, Marie-Claude Gingras, and Josée N. Lavoie
Activation of Adenovirus Type 2 Early Region 4 ORF4 Cytoplasmic Death Function by Direct Binding to Src Kinase Domain
J. Biol. Chem. 2004 279: 25905-25915. First Published on April 7, 2004; doi:10.1074/jbc.M400933200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Yusuke Satoh, Itaru Matsumura, Hirokazu Tanaka, Sachiko Ezoe, Hiroyuki Sugahara, Masao Mizuki, Hirohiko Shibayama, Eri Ishiko, Jun Ishiko, Koichi Nakajima, and Yuzuru Kanakura
Roles for c-Myc in Self-renewal of Hematopoietic Stem Cells
J. Biol. Chem. 2004 279: 24986-24993. First Published on April 2, 2004; doi:10.1074/jbc.M400407200 [Abstract] [Full Text] [PDF]  

Paige S. Davies and Caroline A. Enns
Expression of the Hereditary Hemochromatosis Protein HFE Increases Ferritin Levels by Inhibiting Iron Export in HT29 Cells
J. Biol. Chem. 2004 279: 25085-25092. First Published on March 25, 2004; doi:10.1074/jbc.M400537200 [Abstract] [Full Text] [PDF]  

Tomohiro Ito, Shin-ichi Tsukumo, Norio Suzuki, Hozumi Motohashi, Masayuki Yamamoto, Yoshiaki Fujii-Kuriyama, Junsei Mimura, Tien-Min Lin, Richard E. Peterson, Chiharu Tohyama, and Keiko Nohara
A Constitutively Active Arylhydrocarbon Receptor Induces Growth Inhibition of Jurkat T Cells through Changes in the Expression of Genes Related to Apoptosis and Cell Cycle Arrest
J. Biol. Chem. 2004 279: 25204-25210. First Published on April 6, 2004; doi:10.1074/jbc.M402143200 [Abstract] [Full Text] [PDF]  

Dimitra Makatsori, Niki Kourmouli, Hara Polioudaki, Leonard D. Shultz, Kelvin Mclean, Panayiotis A. Theodoropoulos, Prim B. Singh, and Spyros D. Georgatos
The Inner Nuclear Membrane Protein Lamin B Receptor Forms Distinct Microdomains and Links Epigenetically Marked Chromatin to the Nuclear Envelope
J. Biol. Chem. 2004 279: 25567-25573. First Published on March 31, 2004; doi:10.1074/jbc.M313606200 [Abstract] [Full Text] [PDF]  

Hiroshi Kogo, Toshisada Aiba, and Toyoshi Fujimoto
Cell Type-specific Occurrence of Caveolin-1{alpha} and -1{beta} in the Lung Caused by Expression of Distinct mRNAs
J. Biol. Chem. 2004 279: 25574-25581. First Published on April 2, 2004; doi:10.1074/jbc.M310807200 [Abstract] [Full Text] [PDF]  

María B. Durán Alonso, Georg Zoidl, Carla Taveggia, Frank Bosse, Christiane Zoidl, Mary Rahman, Eric Parmantier, Charlotte H. Dean, Brett S. Harris, Lawrence Wrabetz, Hans Werner Müller, Kristjan R. Jessen, and Rhona Mirsky
Identification and Characterization of ZFP-57, a Novel Zinc Finger Transcription Factor in the Mammalian Peripheral Nervous System
J. Biol. Chem. 2004 279: 25653-25664. First Published on April 7, 2004; doi:10.1074/jbc.M400415200 [Abstract] [Full Text] [PDF]  

Didier M. Hodzic, David B. Yeater, Luiza Bengtsson, Henning Otto, and Philip D. Stahl
Sun2 Is a Novel Mammalian Inner Nuclear Membrane Protein
J. Biol. Chem. 2004 279: 25805-25812. First Published on April 12, 2004; doi:10.1074/jbc.M313157200 [Abstract] [Full Text] [PDF]  

Anthony M. Giannetti and Pamela J. Björkman
HFE and Transferrin Directly Compete for Transferrin Receptor in Solution and at the Cell Surface
J. Biol. Chem. 2004 279: 25866-25875. First Published on March 31, 2004; doi:10.1074/jbc.M401467200 [Abstract] [Full Text] [PDF]  

Jong S. Rim, Bingzhong Xue, Barbara Gawronska-Kozak, and Leslie P. Kozak
Sequestration of Thermogenic Transcription Factors in the Cytoplasm during Development of Brown Adipose Tissue
J. Biol. Chem. 2004 279: 25916-25926. First Published on April 8, 2004; doi:10.1074/jbc.M402102200 [Abstract] [Full Text] [PDF]  

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