JBC -- Table of Contents (Aug 6 2004, 279, (32))

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David R. Evans and Hedeel I. Guy: Mammalian Pyrimidine Biosynthesis: Fresh Insights into an Ancient Pathway
J. Biol. Chem. 2004 279: 33035-33038. First Published on April 19, 2004; doi:10.1074/jbc.R400007200 [Full Text] [PDF]

Accelerated Publications:

K. Vinod Vijayan, Yan Liu, Tong-Tong Li, and Paul F. Bray: Protein Phosphatase 1 Associates with the Integrin ${alpha}$ _IIb Subunit and Regulates Signaling
J. Biol. Chem. 2004 279: 33039-33042. First Published on June 17, 2004; doi:10.1074/jbc.C400239200 [Abstract] [Full Text] [PDF]

Aviva S. Meyer, Maureen Blandino, and Thomas E. Spratt: Escherichia coli DNA Polymerase I (Klenow Fragment) Uses a Hydrogen-bonding Fork from Arg⁶⁶⁸ to the Primer Terminus and Incoming Deoxynucleotide Triphosphate to Catalyze DNA Replication
J. Biol. Chem. 2004 279: 33043-33046. First Published on June 20, 2004; doi:10.1074/jbc.C400232200 [Abstract] [Full Text] [PDF] Supplemental Data

Jeffrey G. Bertram, Linda B. Bloom, Mike O'Donnell, and Myron F. Goodman: Increased dNTP Binding Affinity Reveals a Nonprocessive Role for Escherichia coli ${beta}$ Clamp with DNA Polymerase IV
J. Biol. Chem. 2004 279: 33047-33050. First Published on June 20, 2004; doi:10.1074/jbc.C400265200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Alessandra Napoli, Anna Valenti, Vincenzo Salerno, Marc Nadal, Florence Garnier, Mosè Rossi, and Maria Ciaramella: Reverse Gyrase Recruitment to DNA after UV Light Irradiation in Sulfolobus solfataricus
J. Biol. Chem. 2004 279: 33192-33198. First Published on June 8, 2004; doi:10.1074/jbc.M402619200 [Abstract] [Full Text] [PDF]

Olivier Sordet, ZhiYong Liao, Hong Liu, Smitha Antony, Ellen V. Stevens, Glenda Kohlhagen, Haiqing Fu, and Yves Pommier: Topoisomerase I-DNA Complexes Contribute to Arsenic Trioxide-induced Apoptosis
J. Biol. Chem. 2004 279: 33968-33975. First Published on June 3, 2004; doi:10.1074/jbc.M404620200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Bin Xu and Ronald J. Koenig: An RNA-binding Domain in the Thyroid Hormone Receptor Enhances Transcriptional Activation
J. Biol. Chem. 2004 279: 33051-33056. First Published on June 4, 2004; doi:10.1074/jbc.M404930200 [Abstract] [Full Text] [PDF]

Christopher D. Carvin and Michael P. Kladde: Effectors of Lysine 4 Methylation of Histone H3 in Saccharomyces cerevisiae Are Negative Regulators of PHO5 and GAL1-10
J. Biol. Chem. 2004 279: 33057-33062. First Published on June 4, 2004; doi:10.1074/jbc.M405033200 [Abstract] [Full Text] [PDF]

Marcos Rivas, Britt Mellström, José R. Naranjo, and Pilar Santisteban: Transcriptional Repressor DREAM Interacts with Thyroid Transcription Factor-1 and Regulates Thyroglobulin Gene Expression
J. Biol. Chem. 2004 279: 33114-33122. First Published on June 4, 2004; doi:10.1074/jbc.M403526200 [Abstract] [Full Text] [PDF]

Hyoung Seok Kim, Tae Sun Kang, Joon Sik Hyun, and Hyen Sam Kang: Regulation of Penicillin G Acylase Gene Expression in Escherichia coli by Repressor PaaX and the cAMP-cAMP Receptor Protein Complex
J. Biol. Chem. 2004 279: 33253-33262. First Published on May 24, 2004; doi:10.1074/jbc.M404348200 [Abstract] [Full Text] [PDF] Supplemental Data

Patricia Stanhope-Baker, Patricia M. Kessler, Wenliang Li, Munna L. Agarwal, and Bryan R. G. Williams: The Wilms Tumor Suppressor-1 Target Gene Podocalyxin Is Transcriptionally Repressed by p53
J. Biol. Chem. 2004 279: 33575-33585. First Published on May 21, 2004; doi:10.1074/jbc.M404787200 [Abstract] [Full Text] [PDF]

Bharat Khurana and Thomas M. Kristie: A Protein Sequestering System Reveals Control of Cellular Programs by the Transcriptional Coactivator HCF-1
J. Biol. Chem. 2004 279: 33673-33683. First Published on June 8, 2004; doi:10.1074/jbc.M401255200 [Abstract] [Full Text] [PDF] [Papers Of The Week]

Karanam Balasubramanyam, M. Altaf, Radhika A. Varier, V. Swaminathan, Aarti Ravindran, Parag P. Sadhale, and Tapas K. Kundu: Polyisoprenylated Benzophenone, Garcinol, a Natural Histone Acetyltransferase Inhibitor, Represses Chromatin Transcription and Alters Global Gene Expression
J. Biol. Chem. 2004 279: 33716-33726. First Published on May 19, 2004; doi:10.1074/jbc.M402839200 [Abstract] [Full Text] [PDF]

Aihua Zhang, Percy Luk Yeung, Chia-Wei Li, Shih-Chieh Tsai, Gia Khanh Dinh, Xiaoyang Wu, Hui Li, and J. Don Chen: Identification of a Novel Family of Ankyrin Repeats Containing Cofactors for p160 Nuclear Receptor Coactivators
J. Biol. Chem. 2004 279: 33799-33805. First Published on June 7, 2004; doi:10.1074/jbc.M403997200 [Abstract] [Full Text] [PDF]

Hiroko Akiyoshi, Shigetsugu Hatakeyama, Jukka Pitkänen, Yasuhiro Mouri, Vassilis Doucas, Jun Kudoh, Kyoko Tsurugaya, Daisuke Uchida, Akemi Matsushima, Kiyotaka Oshikawa, Keiichi I. Nakayama, Nobuyoshi Shimizu, Pärt Peterson, and Mitsuru Matsumoto: Subcellular Expression of Autoimmune Regulator Is Organized in a Spatiotemporal Manner
J. Biol. Chem. 2004 279: 33984-33991. First Published on May 17, 2004; doi:10.1074/jbc.M400702200 [Abstract] [Full Text] [PDF] Supplemental Data

RNA: Structure, Metabolism, and Catalysis:

Yuko Seko, Hooman Azmi, Robert Fariss, and Jack A. Ragheb: Selective Cytoplasmic Translocation of HuR and Site-specific Binding to the Interleukin-2 mRNA Are Not Sufficient for CD28-mediated Stabilization of the mRNA
J. Biol. Chem. 2004 279: 33359-33367. First Published on March 12, 2004; doi:10.1074/jbc.M312306200 [Abstract] [Full Text] [PDF]

Sébastien Degot, Hervé Le Hir, Fabien Alpy, Valérie Kedinger, Isabelle Stoll, Corinne Wendling, Bertrand Seraphin, Marie-Christine Rio, and Catherine Tomasetto: Association of the Breast Cancer Protein MLN51 with the Exon Junction Complex via Its Speckle Localizer and RNA Binding Module
J. Biol. Chem. 2004 279: 33702-33715. First Published on May 27, 2004; doi:10.1074/jbc.M402754200 [Abstract] [Full Text] [PDF]

Zdravko J. Lorkovic, Sergiy Lopato, Monika Pexa, Reinhard Lehner, and Andrea Barta: Interactions of Arabidopsis RS Domain Containing Cyclophilins with SR Proteins and U1 and U11 Small Nuclear Ribonucleoprotein-specific Proteins Suggest Their Involvement in Pre-mRNA Splicing
J. Biol. Chem. 2004 279: 33890-33898. First Published on May 27, 2004; doi:10.1074/jbc.M400270200 [Abstract] [Full Text] [PDF] Supplemental Data

Protein Synthesis, Post-Translation Modification, and Degradation:

Stephanie L. H. Miller, Erica Malotky, and John P. O'Bryan: Analysis of the Role of Ubiquitin-interacting Motifs in Ubiquitin Binding and Ubiquitylation
J. Biol. Chem. 2004 279: 33528-33537. First Published on May 21, 2004; doi:10.1074/jbc.M313097200 [Abstract] [Full Text] [PDF] Supplemental Data

June Coronella-Wood, Jerome Terrand, Haipeng Sun, and Qin M. Chen: c-Fos Phosphorylation Induced by H₂O₂ Prevents Proteasomal Degradation of c-Fos in Cardiomyocytes
J. Biol. Chem. 2004 279: 33567-33574. First Published on May 10, 2004; doi:10.1074/jbc.M404013200 [Abstract] [Full Text] [PDF]

Derek E. Dimcheff, Mark A. Faasse, Frank J. McAtee, and John L. Portis: Endoplasmic Reticulum (ER) Stress Induced by a Neurovirulent Mouse Retrovirus Is Associated with Prolonged BiP Binding and Retention of a Viral Protein in the ER
J. Biol. Chem. 2004 279: 33782-33790. First Published on June 3, 2004; doi:10.1074/jbc.M403304200 [Abstract] [Full Text] [PDF]

Atish D. Choudhury, Hong Xu, and Richard Baer: Ubiquitination and Proteasomal Degradation of the BRCA1 Tumor Suppressor Is Regulated during Cell Cycle Progression
J. Biol. Chem. 2004 279: 33909-33918. First Published on May 27, 2004; doi:10.1074/jbc.M403646200 [Abstract] [Full Text] [PDF] Supplemental Data

Genomics, Proteomics, and Bioinformatics:

Jolyne Drummelsmith, Isabelle Girard, Nathalie Trudel, and Marc Ouellette: Differential Protein Expression Analysis of Leishmania major Reveals Novel Roles for Methionine Adenosyltransferase and S-Adenosylmethionine in Methotrexate Resistance
J. Biol. Chem. 2004 279: 33273-33280. First Published on June 9, 2004; doi:10.1074/jbc.M405183200 [Abstract] [Full Text] [PDF]

Alfred C. O. Vertegaal, Stephen C. Ogg, Ellis Jaffray, Manuel S. Rodriguez, Ronald T. Hay, Jens S. Andersen, Matthias Mann, and Angus I. Lamond: A Proteomic Study of SUMO-2 Target Proteins
J. Biol. Chem. 2004 279: 33791-33798. First Published on June 2, 2004; doi:10.1074/jbc.M404201200 [Abstract] [Full Text] [PDF] Supplemental Data

Protein Structure and Folding:

Mari Cruz Pérez-Marín, Jose Juan López-Rubio, Francisco Jose Murillo, Montserrat Elías-Arnanz, and S. Padmanabhan: The N Terminus of Myxococcus xanthus CarA Repressor Is an Autonomously Folding Domain That Mediates Physical and Functional Interactions with Both Operator DNA and Antirepressor Protein
J. Biol. Chem. 2004 279: 33093-33103. First Published on May 25, 2004; doi:10.1074/jbc.M405225200 [Abstract] [Full Text] [PDF]

Chi Chae, Suveena Sharma, Joel R. Hoskins, and Sue Wickner: CbpA, a DnaJ Homolog, Is a DnaK Co-chaperone, and Its Activity Is Modulated by CbpM
J. Biol. Chem. 2004 279: 33147-33153. First Published on June 7, 2004; doi:10.1074/jbc.M404862200 [Abstract] [Full Text] [PDF] [Papers Of The Week]

Shan Cen, Fei Guo, Meijuan Niu, Jenan Saadatmand, Julien Deflassieux, and Lawrence Kleiman: The Interaction between HIV-1 Gag and APOBEC3G
J. Biol. Chem. 2004 279: 33177-33184. First Published on May 24, 2004; doi:10.1074/jbc.M402062200 [Abstract] [Full Text] [PDF]

Kevin D. Clark, Stephen F. Garczynski, Aditi Arora, Joe W. Crim, and Michael R. Strand: Specific Residues in Plasmatocyte-spreading Peptide Are Required for Receptor Binding and Functional Antagonism of Insect Immune Cells
J. Biol. Chem. 2004 279: 33246-33252. First Published on June 10, 2004; doi:10.1074/jbc.M401157200 [Abstract] [Full Text] [PDF]

Emerson Luiz Gelamo, Rosangela Itri, and Marcel Tabak: Small Angle X-ray Scattering (SAXS) Study of the Extracellular Hemoglobin of Glossoscolex paulistus: EFFECT OF pH, IRON OXIDATION STATE, AND INTERACTION WITH ANIONIC SDS SURFACTANT
J. Biol. Chem. 2004 279: 33298-33305. First Published on April 19, 2004; doi:10.1074/jbc.M401982200 [Abstract] [Full Text] [PDF]

Laura Spagnolo, Imre Törö, Melania D'Orazio, Peter O'Neill, Jens Z. Pedersen, Oliviero Carugo, Giuseppe Rotilio, Andrea Battistoni, and Kristina Djinovic-Carugo: Unique Features of the sodC-encoded Superoxide Dismutase from Mycobacterium tuberculosis, a Fully Functional Copper-containing Enzyme Lacking Zinc in the Active Site
J. Biol. Chem. 2004 279: 33447-33455. First Published on May 23, 2004; doi:10.1074/jbc.M404699200 [Abstract] [Full Text] [PDF]

Finn Stausholm Nielsen, Jørgen Sauer, Johan Bäcklund, Bjørn Voldborg, Klaus Gregorius, Søren Mouritsen, and Tomas Bratt: Insertion of Foreign T Cell Epitopes in Human Tumor Necrosis Factor ${alpha}$ with Minimal Effect on Protein Structure and Biological Activity
J. Biol. Chem. 2004 279: 33593-33600. First Published on June 1, 2004; doi:10.1074/jbc.M403072200 [Abstract] [Full Text] [PDF]

Sergio Apuzzo, Aliaa Abdelhakim, Anouk S. Fortin, and Philippe Gros: Cross-talk between the Paired Domain and the Homeodomain of Pax3: DNA BINDING BY EACH DOMAIN CAUSES A STRUCTURAL CHANGE IN THE OTHER DOMAIN, SUPPORTING INTERDEPENDENCE FOR DNA BINDING
J. Biol. Chem. 2004 279: 33601-33612. First Published on May 17, 2004; doi:10.1074/jbc.M402949200 [Abstract] [Full Text] [PDF] Supplemental Data

Holger Greschik, Ralf Flaig, Jean-Paul Renaud, and Dino Moras: Structural Basis for the Deactivation of the Estrogen-related Receptor ${gamma}$ by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity
J. Biol. Chem. 2004 279: 33639-33646. First Published on May 24, 2004; doi:10.1074/jbc.M402195200 [Abstract] [Full Text] [PDF]

Alessandra Pesce, Marco Nardini, Paolo Ascenzi, Eva Geuens, Sylvia Dewilde, Luc Moens, Martino Bolognesi, Austen F. Riggs, Angela Hale, Pengchi Deng, G. Ulrich Nienhaus, John S. Olson, and Karin Nienhaus: Thr-E11 Regulates O₂ Affinity in Cerebratulus lacteus Mini-hemoglobin
J. Biol. Chem. 2004 279: 33662-33672. First Published on May 25, 2004; doi:10.1074/jbc.M403597200 [Abstract] [Full Text] [PDF]

James F. Sinclair and Alison D. O'Brien: Intimin Types ${alpha}$ , ${beta}$ , and ${gamma}$ Bind to Nucleolin with Equivalent Affinity but Lower Avidity than to the Translocated Intimin Receptor
J. Biol. Chem. 2004 279: 33751-33758. First Published on June 1, 2004; doi:10.1074/jbc.M401616200 [Abstract] [Full Text] [PDF]

Masaki Mishima, Yasunari Sakai, Noriyuki Itoh, Hiroyuki Kamiya, Masato Furuichi, Masayuki Takahashi, Yuriko Yamagata, Shigenori Iwai, Yusaku Nakabeppu, and Masahiro Shirakawa: Structure of Human MTH1, a Nudix Family Hydrolase That Selectively Degrades Oxidized Purine Nucleoside Triphosphates
J. Biol. Chem. 2004 279: 33806-33815. First Published on May 7, 2004; doi:10.1074/jbc.M402393200 [Abstract] [Full Text] [PDF]

Angela V. Toms, Cynthia Kinsland, Diane E. McCloskey, Anthony E. Pegg, and Steven E. Ealick: Evolutionary Links as Revealed by the Structure of Thermotoga maritima S-Adenosylmethionine Decarboxylase
J. Biol. Chem. 2004 279: 33837-33846. First Published on May 18, 2004; doi:10.1074/jbc.M403369200 [Abstract] [Full Text] [PDF]

Achim Thomzig, Sashko Spassov, Manuela Friedrich, Dieter Naumann, and Michael Beekes: Discriminating Scrapie and Bovine Spongiform Encephalopathy Isolates by Infrared Spectroscopy of Pathological Prion Protein
J. Biol. Chem. 2004 279: 33847-33854. First Published on May 20, 2004; doi:10.1074/jbc.M403730200 [Abstract] [Full Text] [PDF]

Zhilei Chen, Benita S. Katzenellenbogen, John A. Katzenellenbogen, and Huimin Zhao: Directed Evolution of Human Estrogen Receptor Variants with Significantly Enhanced Androgen Specificity and Affinity
J. Biol. Chem. 2004 279: 33855-33864. First Published on May 24, 2004; doi:10.1074/jbc.M402118200 [Abstract] [Full Text] [PDF] Supplemental Data

Wanyun Sheng, Hong Yan, Francisco M. Rausa, III, Robert H. Costa, and Xiubei Liao: Structure of the Hepatocyte Nuclear Factor 6 ${alpha}$ and Its Interaction with DNA
J. Biol. Chem. 2004 279: 33928-33936. First Published on May 28, 2004; doi:10.1074/jbc.M403805200 [Abstract] [Full Text] [PDF]

Xiang Xu, Jingyue Zhao, Zhen Xu, Baozhen Peng, Qiuhua Huang, Eddy Arnold, and Jianping Ding: Structures of Human Cytosolic NADP-dependent Isocitrate Dehydrogenase Reveal a Novel Self-regulatory Mechanism of Activity
J. Biol. Chem. 2004 279: 33946-33957. First Published on June 1, 2004; doi:10.1074/jbc.M404298200 [Abstract] [Full Text] [PDF]

Matthew Revington, Tina M. Holder, and Erik R. P. Zuiderweg: NMR Study of Nucleotide-induced Changes in the Nucleotide Binding Domain of Thermus thermophilus Hsp70 Chaperone DnaK: IMPLICATIONS FOR THE ALLOSTERIC MECHANISM
J. Biol. Chem. 2004 279: 33958-33967. First Published on June 2, 2004; doi:10.1074/jbc.M313967200 [Abstract] [Full Text] [PDF]

Mark R. Swingle, Richard E. Honkanen, and Ewa M. Ciszak: Structural Basis for the Catalytic Activity of Human Serine/Threonine Protein Phosphatase-5
J. Biol. Chem. 2004 279: 33992-33999. First Published on May 23, 2004; doi:10.1074/jbc.M402855200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Keiji Nogami, Jan Freas, Chandrashekhara Manithody, Hironao Wakabayashi, Alireza R. Rezaie, and Philip J. Fay: Mechanisms of Interactions of Factor X and Factor Xa with the Acidic Region in the Factor VIII A1 Domain
J. Biol. Chem. 2004 279: 33104-33113. First Published on May 27, 2004; doi:10.1074/jbc.M405537200 [Abstract] [Full Text] [PDF]

Subhendu Mukhopadhyay, Hidayatullah G. Munshi, Suman Kambhampati, Antonella Sassano, Leonidas C. Platanias, and M. Sharon Stack: Calcium-induced Matrix Metalloproteinase 9 Gene Expression Is Differentially Regulated by ERK1/2 and p38 MAPK in Oral Keratinocytes and Oral Squamous Cell Carcinoma
J. Biol. Chem. 2004 279: 33139-33146. First Published on June 4, 2004; doi:10.1074/jbc.M405194200 [Abstract] [Full Text] [PDF]

Jean-Michel Longpré and Richard Leduc: Identification of Prodomain Determinants Involved in ADAMTS-1 Biosynthesis
J. Biol. Chem. 2004 279: 33237-33245. First Published on June 7, 2004; doi:10.1074/jbc.M313151200 [Abstract] [Full Text] [PDF]

Giorgio Ricci, Paola Turella, Francesca De Maria, Giovanni Antonini, Luisa Nardocci, Philip G. Board, Michael W. Parker, Maria Grazia Carbonelli, Giorgio Federici, and Anna Maria Caccuri: Binding and Kinetic Mechanisms of the Zeta Class Glutathione Transferase
J. Biol. Chem. 2004 279: 33336-33342. First Published on June 1, 2004; doi:10.1074/jbc.M404631200 [Abstract] [Full Text] [PDF]

Joseph M. Jez, Rebecca E. Cahoon, and Sixue Chen: Arabidopsis thaliana Glutamate-Cysteine Ligase: FUNCTIONAL PROPERTIES, KINETIC MECHANISM, AND REGULATION OF ACTIVITY
J. Biol. Chem. 2004 279: 33463-33470. First Published on June 4, 2004; doi:10.1074/jbc.M405127200 [Abstract] [Full Text] [PDF]

Robert H. H. van den Heuvel, Willy A. M. van den Berg, Stefano Rovida, and Willem J. H. van Berkel: Laboratory-evolved Vanillyl-alcohol Oxidase Produces Natural Vanillin
J. Biol. Chem. 2004 279: 33492-33500. First Published on May 28, 2004; doi:10.1074/jbc.M312968200 [Abstract] [Full Text] [PDF]

Elena Newman, Donald E. Spratt, Jennifer Mosher, Bo Cheyne, Heather J. Montgomery, Denney L. Wilson, J. Brice Weinberg, Susan M. E. Smith, John C. Salerno, Dipak K. Ghosh, and J. Guy Guillemette: Differential Activation of Nitric-oxide Synthase Isozymes by Calmodulin-Troponin C Chimeras
J. Biol. Chem. 2004 279: 33547-33557. First Published on May 11, 2004; doi:10.1074/jbc.M403892200 [Abstract] [Full Text] [PDF]

Andrea Schweinitz, Torsten Steinmetzer, Ingo J. Banke, Matthias J. E. Arlt, Anne Stürzebecher, Oliver Schuster, Andreas Geissler, Helmut Giersiefen, Ewa Zeslawska, Uwe Jacob, Achim Krüger, and Jörg Stürzebecher: Design of Novel and Selective Inhibitors of Urokinase-type Plasminogen Activator with Improved Pharmacokinetic Properties for Use as Antimetastatic Agents
J. Biol. Chem. 2004 279: 33613-33622. First Published on May 18, 2004; doi:10.1074/jbc.M314151200 [Abstract] [Full Text] [PDF] Supplemental Data

Paola Sandra Mercuri, Isabel García-Sáez, Kris De Vriendt, Iris Thamm, Bart Devreese, Jozef Van Beeumen, Otto Dideberg, Gian Maria Rossolini, Jean-Marie Frère, and Moreno Galleni: Probing the Specificity of the Subclass B3 FEZ-1 Metallo- ${beta}$ -lactamase by Site-directed Mutagenesis
J. Biol. Chem. 2004 279: 33630-33638. First Published on May 24, 2004; doi:10.1074/jbc.M403671200 [Abstract] [Full Text] [PDF]

Lu Deng, Svetlana V. Markova, Eugene S. Vysotski, Zhi-Jie Liu, John Lee, John Rose, and Bi-Cheng Wang: Crystal Structure of a Ca²⁺-discharged Photoprotein: IMPLICATIONS FOR MECHANISMS OF THE CALCIUM TRIGGER AND BIOLUMINESCENCE
J. Biol. Chem. 2004 279: 33647-33652. First Published on May 20, 2004; doi:10.1074/jbc.M402427200 [Abstract] [Full Text] [PDF]

Dario Segura-Peña, Nikolina Sekulic, Stephan Ort, Manfred Konrad, and Arnon Lavie: Substrate-induced Conformational Changes in Human UMP/CMP Kinase
J. Biol. Chem. 2004 279: 33882-33889. First Published on May 26, 2004; doi:10.1074/jbc.M401989200 [Abstract] [Full Text] [PDF] Supplemental Data

Metabolism and Bioenergetics:

Robin E. Duncan, Ahmed El-Sohemy, and Michael C. Archer: Mevalonate Promotes the Growth of Tumors Derived from Human Cancer Cells in Vivo and Stimulates Proliferation in Vitro with Enhanced Cyclin-dependent Kinase-2 Activity
J. Biol. Chem. 2004 279: 33079-33084. First Published on May 20, 2004; doi:10.1074/jbc.M400732200 [Abstract] [Full Text] [PDF]

Sakurako Ono, Nobuhito Sone, Masasuke Yoshida, and Toshiharu Suzuki: ATP Synthase that Lacks F₀a-Subunit: ISOLATION, PROPERTIES, AND INDICATION OF F₀b₂-SUBUNITS AS AN ANCHOR RAIL OF A ROTATING c-RING
J. Biol. Chem. 2004 279: 33409-33412. First Published on June 2, 2004; doi:10.1074/jbc.M404993200 [Abstract] [Full Text] [PDF]

Hiroaki Yajima, Emiko Ikeshima, Maho Shiraki, Tomoka Kanaya, Daisuke Fujiwara, Hideharu Odai, Nobuyo Tsuboyama-Kasaoka, Osamu Ezaki, Shinichi Oikawa, and Keiji Kondo: Isohumulones, Bitter Acids Derived from Hops, Activate Both Peroxisome Proliferator-activated Receptor ${alpha}$ and ${gamma}$ and Reduce Insulin Resistance
J. Biol. Chem. 2004 279: 33456-33462. First Published on June 3, 2004; doi:10.1074/jbc.M403456200 [Abstract] [Full Text] [PDF]

Antonio G. Cordente, Eduardo López-Viñas, María Irene Vázquez, Jan H. Swiegers, Isak S. Pretorius, Paulino Gómez-Puertas, Fausto G. Hegardt, Guillermina Asins, and Dolors Serra: Redesign of Carnitine Acetyltransferase Specificity by Protein Engineering
J. Biol. Chem. 2004 279: 33899-33908. First Published on May 21, 2004; doi:10.1074/jbc.M402685200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Sung-Kwon Moon, Hong-Man Kim, Young-Choon Lee, and Cheorl-Ho Kim: Disialoganglioside (GD3) Synthase Gene Expression Suppresses Vascular Smooth Muscle Cell Responses via the Inhibition of ERK1/2 Phosphorylation, Cell Cycle Progression, and Matrix Metalloproteinase-9 Expression
J. Biol. Chem. 2004 279: 33063-33070. First Published on June 2, 2004; doi:10.1074/jbc.M313462200 [Abstract] [Full Text] [PDF]

Ellis Van Liempt, Anne Imberty, Christine M. C. Bank, Sandra J. Van Vliet, Yvette Van Kooyk, Teunis B. H. Geijtenbeek, and Irma Van Die: Molecular Basis of the Differences in Binding Properties of the Highly Related C-type Lectins DC-SIGN and L-SIGN to Lewis X Trisaccharide and Schistosoma mansoni Egg Antigens
J. Biol. Chem. 2004 279: 33161-33167. First Published on June 7, 2004; doi:10.1074/jbc.M404988200 [Abstract] [Full Text] [PDF]

Ikuko Kakizaki, Kaoru Kojima, Keiichi Takagaki, Masahiko Endo, Reiji Kannagi, Masaki Ito, Yoshihiro Maruo, Hiroshi Sato, Tadashi Yasuda, Satoka Mita, Koji Kimata, and Naoki Itano: A Novel Mechanism for the Inhibition of Hyaluronan Biosynthesis by 4-Methylumbelliferone
J. Biol. Chem. 2004 279: 33281-33289. First Published on June 9, 2004; doi:10.1074/jbc.M405918200 [Abstract] [Full Text] [PDF]

Masashi Nishio, Satoshi Fukumoto, Keiko Furukawa, Akiko Ichimura, Hiroshi Miyazaki, Susumu Kusunoki, Takeshi Urano, and Koichi Furukawa: Overexpressed GM1 Suppresses Nerve Growth Factor (NGF) Signals by Modulating the Intracellular Localization of NGF Receptors and Membrane Fluidity in PC12 Cells
J. Biol. Chem. 2004 279: 33368-33378. First Published on May 15, 2004; doi:10.1074/jbc.M403816200 [Abstract] [Full Text] [PDF]

Yasuhiro Horibata, Keishi Sakaguchi, Nozomu Okino, Hiroshi Iida, Masanori Inagaki, Toshitaka Fujisawa, Yoichiro Hama, and Makoto Ito: Unique Catabolic Pathway of Glycosphingolipids in a Hydrozoan, Hydra magnipapillata, Involving Endoglycoceramidase
J. Biol. Chem. 2004 279: 33379-33389. First Published on May 19, 2004; doi:10.1074/jbc.M401460200 [Abstract] [Full Text] [PDF]

Nadia Vadaie and Donald L. Jarvis: Molecular Cloning and Functional Characterization of a Lepidopteran Insect ${beta}$ 4-N-Acetylgalactosaminyltransferase with Broad Substrate Specificity, a Functional Role in Glycoprotein Biosynthesis, and a Potential Functional Role in Glycolipid Biosynthesis
J. Biol. Chem. 2004 279: 33501-33518. First Published on June 1, 2004; doi:10.1074/jbc.M404925200 [Abstract] [Full Text] [PDF]

Linda J. Olson, Nancy M. Dahms, and Jung-Ja P. Kim: The N-terminal Carbohydrate Recognition Site of the Cation-independent Mannose 6-Phosphate Receptor
J. Biol. Chem. 2004 279: 34000-34009. First Published on May 28, 2004; doi:10.1074/jbc.M404588200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Harry R. Davis, Jr., Li-ji Zhu, Lizbeth M. Hoos, Glen Tetzloff, Maureen Maguire, Jianjun Liu, Xiaorui Yao, Sai Prasad N. Iyer, My-Hanh Lam, Erik G. Lund, Patricia A. Detmers, Michael P. Graziano, and Scott W. Altmann: Niemann-Pick C1 Like 1 (NPC1L1) Is the Intestinal Phytosterol and Cholesterol Transporter and a Key Modulator of Whole-body Cholesterol Homeostasis
J. Biol. Chem. 2004 279: 33586-33592. First Published on June 1, 2004; doi:10.1074/jbc.M405817200 [Abstract] [Full Text] [PDF]

Peter Michaely, Wei-Ping Li, Richard G. W. Anderson, Jonathan C. Cohen, and Helen H. Hobbs: The Modular Adaptor Protein ARH Is Required for Low Density Lipoprotein (LDL) Binding and Internalization but Not for LDL Receptor Clustering in Coated Pits
J. Biol. Chem. 2004 279: 34023-34031. First Published on May 27, 2004; doi:10.1074/jbc.M405242200 [Abstract] [Full Text] [PDF]

Jerzy-Roch Nofer, Grazyna Herminghaus, Martin Brodde, Eberhard Morgenstern, Stephan Rust, Thomas Engel, Udo Seedorf, Gerd Assmann, Horst Bluethmann, and Beate E. Kehrel: Impaired Platelet Activation in Familial High Density Lipoprotein Deficiency (Tangier Disease)
J. Biol. Chem. 2004 279: 34032-34037. First Published on May 25, 2004; doi:10.1074/jbc.M405174200 [Abstract] [Full Text] [PDF]

Blandine Kedjouar, Philippe de Médina, Mustapha Oulad-Abdelghani, Bruno Payré, Sandrine Silvente-Poirot, Gilles Favre, Jean-Charles Faye, and Marc Poirot: Molecular Characterization of the Microsomal Tamoxifen Binding Site
J. Biol. Chem. 2004 279: 34048-34061. First Published on June 2, 2004; doi:10.1074/jbc.M405230200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Nicolas Joly, Alex Böhm, Winfried Boos, and Evelyne Richet: MalK, the ATP-binding Cassette Component of the Escherichia coli Maltodextrin Transporter, Inhibits the Transcriptional Activator MalT by Antagonizing Inducer Binding
J. Biol. Chem. 2004 279: 33123-33130. First Published on June 4, 2004; doi:10.1074/jbc.M403615200 [Abstract] [Full Text] [PDF]

Emma Jean Bowman, Laurie A. Graham, Tom H. Stevens, and Barry J. Bowman: The Bafilomycin/Concanamycin Binding Site in Subunit c of the V-ATPases from Neurospora crassa and Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 33131-33138. First Published on June 4, 2004; doi:10.1074/jbc.M404638200 [Abstract] [Full Text] [PDF]

He-Ping Ma, Otor Al-Khalili, Semra Ramosevac, Sunil Saxena, You-You Liang, David G. Warnock, and Douglas C. Eaton: Steroids and Exogenous ${gamma}$ -ENaC Subunit Modulate Cation Channels Formed by ${alpha}$ -ENaC in Human B Lymphocytes
J. Biol. Chem. 2004 279: 33206-33212. First Published on June 8, 2004; doi:10.1074/jbc.M405455200 [Abstract] [Full Text] [PDF]

Nanette Kälin, José Fernandes, Sigrún Hrafnsdóttir, and Gerrit van Meer: Natural Phosphatidylcholine Is Actively Translocated across the Plasma Membrane to the Surface of Mammalian Cells
J. Biol. Chem. 2004 279: 33228-33236. First Published on June 2, 2004; doi:10.1074/jbc.M401751200 [Abstract] [Full Text] [PDF]

Kathleen A. Kennedy, Eliora G. Gachelet, and Beth Traxler: Evidence for Multiple Pathways in the Assembly of the Escherichia coli Maltose Transport Complex
J. Biol. Chem. 2004 279: 33290-33297. First Published on June 10, 2004; doi:10.1074/jbc.M403796200 [Abstract] [Full Text] [PDF]

Joacir Stolarz Oliveira, Elisa Redaelli, André J. Zaharenko, Rita Restano Cassulini, Katsuhiro Konno, Daniel C. Pimenta, José C. Freitas, Jeffrey J. Clare, and Enzo Wanke: Binding Specificity of Sea Anemone Toxins to Na_v 1.1-1.6 Sodium Channels: UNEXPECTED CONTRIBUTIONS FROM DIFFERENCES IN THE IV/S3-S4 OUTER LOOP
J. Biol. Chem. 2004 279: 33323-33335. First Published on May 28, 2004; doi:10.1074/jbc.M404344200 [Abstract] [Full Text] [PDF]

Jagath R. Junutula, Eric Schonteich, Gayle M. Wilson, Andrew A. Peden, Richard H. Scheller, and Rytis Prekeris: Molecular Characterization of Rab11 Interactions with Members of the Family of Rab11-interacting Proteins
J. Biol. Chem. 2004 279: 33430-33437. First Published on June 1, 2004; doi:10.1074/jbc.M404633200 [Abstract] [Full Text] [PDF] Suppplemental Data

Liangtao Li and Jerry Kaplan: A Mitochondrial-Vacuolar Signaling Pathway in Yeast That Affects Iron and Copper Metabolism
J. Biol. Chem. 2004 279: 33653-33661. First Published on May 25, 2004; doi:10.1074/jbc.M403146200 [Abstract] [Full Text] [PDF]

Gbolahan W. Okunade, Marian L. Miller, Gail J. Pyne, Roy L. Sutliff, Kyle T. O'Connor, Jonathan C. Neumann, Anastasia Andringa, Daniel A. Miller, Vikram Prasad, Thomas Doetschman, Richard J. Paul, and Gary E. Shull: Targeted Ablation of Plasma Membrane Ca²⁺-ATPase (PMCA) 1 and 4 Indicates a Major Housekeeping Function for PMCA1 and a Critical Role in Hyperactivated Sperm Motility and Male Fertility for PMCA4
J. Biol. Chem. 2004 279: 33742-33750. First Published on June 3, 2004; doi:10.1074/jbc.M404628200 [Abstract] [Full Text] [PDF]

Erin A. McCarthy, Steven A. Titus, Shirley M. Taylor, Colleen Jackson-Cook, and Richard G. Moran: A Mutation Inactivating the Mitochondrial Inner Membrane Folate Transporter Creates a Glycine Requirement for Survival of Chinese Hamster Cells
J. Biol. Chem. 2004 279: 33829-33836. First Published on May 12, 2004; doi:10.1074/jbc.M403677200 [Abstract] [Full Text] [PDF]

Hideaki Kanki, Sabina Kupershmidt, Tao Yang, Sam Wells, and Dan M. Roden: A Structural Requirement for Processing the Cardiac K⁺ Channel KCNQ1
J. Biol. Chem. 2004 279: 33976-33983. First Published on May 12, 2004; doi:10.1074/jbc.M404539200 [Abstract] [Full Text] [PDF] Supplemental Data

Mechanisms Of Signal Transduction:

Christina C. N. Wu, Jongdae Lee, Eyal Raz, Maripat Corr, and Dennis A. Carson: Necessity of Oligonucleotide Aggregation for Toll-like Receptor 9 Activation
J. Biol. Chem. 2004 279: 33071-33078. First Published on June 7, 2004; doi:10.1074/jbc.M311662200 [Abstract] [Full Text] [PDF]

Janel K. Warmka, Laura J. Mauro, and Elizabeth V. Wattenberg: Mitogen-activated Protein Kinase Phosphatase-3 Is a Tumor Promoter Target in Initiated Cells That Express Oncogenic Ras
J. Biol. Chem. 2004 279: 33085-33092. First Published on May 24, 2004; doi:10.1074/jbc.M403120200 [Abstract] [Full Text] [PDF]

Alessandra Besana, Andrea Barbuti, Miyuki A. Tateyama, Aviva J. Symes, Richard B. Robinson, and Steven J. Feinmark: Activation of Protein Kinase C ${epsilon}$ Inhibits the Two-pore Domain K⁺ Channel, TASK-1, Inducing Repolarization Abnormalities in Cardiac Ventricular Myocytes
J. Biol. Chem. 2004 279: 33154-33160. First Published on June 7, 2004; doi:10.1074/jbc.M403525200 [Abstract] [Full Text] [PDF]

Jonathan T. Huntington, Janiel M. Shields, Channing J. Der, Colby A. Wyatt, Ulrike Benbow, Craig L. Slingluff, Jr., and Constance E. Brinckerhoff: Overexpression of Collagenase 1 (MMP-1) Is Mediated by the ERK Pathway in Invasive Melanoma Cells: ROLE OF BRAF MUTATION AND FIBROBLAST GROWTH FACTOR SIGNALING
J. Biol. Chem. 2004 279: 33168-33176. First Published on June 7, 2004; doi:10.1074/jbc.M405102200 [Abstract] [Full Text] [PDF]

Thomas H. Lee, Jennifer Shank, Nicole Cusson, and Michelle A. Kelliher: The Kinase Activity of Rip1 Is Not Required for Tumor Necrosis Factor- ${alpha}$ -induced I ${kappa}$ B Kinase or p38 MAP Kinase Activation or for the Ubiquitination of Rip1 by Traf2
J. Biol. Chem. 2004 279: 33185-33191. First Published on June 1, 2004; doi:10.1074/jbc.M404206200 [Abstract] [Full Text] [PDF]

Laura J. Turner, Sarah Nicholls, and Alan Hall: The Activity of the Plexin-A1 Receptor Is Regulated by Rac
J. Biol. Chem. 2004 279: 33199-33205. First Published on June 8, 2004; doi:10.1074/jbc.M402943200 [Abstract] [Full Text] [PDF]

Lin Wang, Joon Hyeok Kwak, Sung Il Kim, Yanjuan He, and Mary E. Choi: Transforming Growth Factor- ${beta}$ 1 Stimulates Vascular Endothelial Growth Factor 164 via Mitogen-activated Protein Kinase Kinase 3-p38 ${alpha}$ and p38 ${delta}$ Mitogen-activated Protein Kinase-dependent Pathway in Murine Mesangial Cells
J. Biol. Chem. 2004 279: 33213-33219. First Published on May 13, 2004; doi:10.1074/jbc.M403758200 [Abstract] [Full Text] [PDF]

Linda Zhai, Deepti Chaturvedi, and Susan Cumberledge: Drosophila Wnt-1 Undergoes a Hydrophobic Modification and Is Targeted to Lipid Rafts, a Process That Requires Porcupine
J. Biol. Chem. 2004 279: 33220-33227. First Published on May 27, 2004; doi:10.1074/jbc.M403407200 [Abstract] [Full Text] [PDF]

Mara Ferrandi, Isabella Molinari, Paolo Barassi, Elena Minotti, Giuseppe Bianchi, and Patrizia Ferrari: Organ Hypertrophic Signaling within Caveolae Membrane Subdomains Triggered by Ouabain and Antagonized by PST 2238
J. Biol. Chem. 2004 279: 33306-33314. First Published on May 25, 2004; doi:10.1074/jbc.M402187200 [Abstract] [Full Text] [PDF]

Shin-Young Park, Hava Karsenty Avraham, and Shalom Avraham: RAFTK/Pyk2 Activation Is Mediated by Trans-acting Autophosphorylation in a Src-independent Manner
J. Biol. Chem. 2004 279: 33315-33322. First Published on May 27, 2004; doi:10.1074/jbc.M313527200 [Abstract] [Full Text] [PDF]

Simon Hör, Heide Pirzer, Laure Dumoutier, Finn Bauer, Sabine Wittmann, Heinrich Sticht, Jean-Christophe Renauld, René de Waal Malefyt, and Helmut Fickenscher: The T-cell Lymphokine Interleukin-26 Targets Epithelial Cells through the Interleukin-20 Receptor 1 and Interleukin-10 Receptor 2 Chains
J. Biol. Chem. 2004 279: 33343-33351. First Published on June 3, 2004; doi:10.1074/jbc.M405000200 [Abstract] [Full Text] [PDF]

Rodrigo Pacheco, Francisco Ciruela, Vicent Casadó, Josefa Mallol, Teresa Gallart, Carmen Lluis, and Rafael Franco: Group I Metabotropic Glutamate Receptors Mediate a Dual Role of Glutamate in T Cell Activation
J. Biol. Chem. 2004 279: 33352-33358. First Published on June 7, 2004; doi:10.1074/jbc.M401761200 [Abstract] [Full Text] [PDF]

Ali Salahpour, Stéphane Angers, Jean-François Mercier, Monique Lagacé, Stefano Marullo, and Michel Bouvier: Homodimerization of the ${beta}$ 2-Adrenergic Receptor as a Prerequisite for Cell Surface Targeting
J. Biol. Chem. 2004 279: 33390-33397. First Published on May 20, 2004; doi:10.1074/jbc.M403363200 [Abstract] [Full Text] [PDF]

Jian-Jiang Hao, Gregory B. Carey, and Xi Zhan: Syk-mediated Tyrosine Phosphorylation Is Required for the Association of Hematopoietic Lineage Cell-specific Protein 1 with Lipid Rafts and B Cell Antigen Receptor Signalosome Complex
J. Biol. Chem. 2004 279: 33413-33420. First Published on May 27, 2004; doi:10.1074/jbc.M313564200 [Abstract] [Full Text] [PDF]

Yueh-Chiang Hu, Shuyuan Yeh, Shauh-Der Yeh, Erik R. Sampson, Jiaoti Huang, Peng Li, Cheng-Lung Hsu, Huei-Ju Ting, Hui-Kuan Lin, Liang Wang, Eungseok Kim, Jing Ni, and Chawnshang Chang: Functional Domain and Motif Analyses of Androgen Receptor Coregulator ARA70 and Its Differential Expression in Prostate Cancer
J. Biol. Chem. 2004 279: 33438-33446. First Published on May 27, 2004; doi:10.1074/jbc.M401781200 [Abstract] [Full Text] [PDF]

Hans H. Bock, Yves Jossin, Petra May, Oliver Bergner, and Joachim Herz: Apolipoprotein E Receptors Are Required for Reelin-induced Proteasomal Degradation of the Neuronal Adaptor Protein Disabled-1
J. Biol. Chem. 2004 279: 33471-33479. First Published on June 2, 2004; doi:10.1074/jbc.M401770200 [Abstract] [Full Text] [PDF]

José Luis Oliva, Natasha Zarich, Natalia Martínez, Rocío Jorge, Antonio Castrillo, Marta Azañedo, Susana García-Vargas, Silvia Gutiérrez-Eisman, Angeles Juarranz, Lisardo Boscá, J. Silvio Gutkind, and José M. Rojas: The P34G Mutation Reduces the Transforming Activity of K-Ras and N-Ras in NIH 3T3 Cells but Not of H-Ras
J. Biol. Chem. 2004 279: 33480-33491. First Published on June 4, 2004; doi:10.1074/jbc.M404058200 [Abstract] [Full Text] [PDF]

Hyun Kim, Qi Li, Barbara L. Hempstead, and Joseph A. Madri: Paracrine and Autocrine Functions of Brain-derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) in Brain-derived Endothelial Cells
J. Biol. Chem. 2004 279: 33538-33546. First Published on May 28, 2004; doi:10.1074/jbc.M404115200 [Abstract] [Full Text] [PDF]

Christian Frank, Ferdinand Molnár, Merja Matilainen, Harri Lempiäinen, and Carsten Carlberg: Agonist-dependent and Agonist-independent Transactivations of the Human Constitutive Androstane Receptor Are Modulated by Specific Amino Acid Pairs
J. Biol. Chem. 2004 279: 33558-33566. First Published on May 19, 2004; doi:10.1074/jbc.M403946200 [Abstract] [Full Text] [PDF]

Hugo Cabedo, Christelle Carteron, and Antonio Ferrer-Montiel: Oligomerization of the Sensory and Motor Neuron-derived Factor Prevents Protein O-Glycosylation
J. Biol. Chem. 2004 279: 33623-33629. First Published on May 24, 2004; doi:10.1074/jbc.M401962200 [Abstract] [Full Text] [PDF]

Saori Sato, Naoya Fujita, and Takashi Tsuruo: Involvement of 3-Phosphoinositide-dependent Protein Kinase-1 in the MEK/MAPK Signal Transduction Pathway
J. Biol. Chem. 2004 279: 33759-33767. First Published on June 2, 2004; doi:10.1074/jbc.M402055200 [Abstract] [Full Text] [PDF]

Abira Sarkar, Yashin Sreenivasan, Govindarajan T. Ramesh, and Sunil K. Manna: ${beta}$ -D-Glucoside Suppresses Tumor Necrosis Factor-induced Activation of Nuclear Transcription Factor ${kappa}$ B but Potentiates Apoptosis
J. Biol. Chem. 2004 279: 33768-33781. First Published on May 25, 2004; doi:10.1074/jbc.M403424200 [Abstract] [Full Text] [PDF]

Kylie J. Ralston, Samantha L. Hird, Xinhai Zhang, Judith L. Scott, Boquan Jin, Rick F. Thorne, Michael C. Berndt, Andrew W. Boyd, and Gordon F. Burns: The LFA-1-associated Molecule PTA-1 (CD226) on T Cells Forms a Dynamic Molecular Complex with Protein 4.1G and Human Discs Large
J. Biol. Chem. 2004 279: 33816-33828. First Published on May 11, 2004; doi:10.1074/jbc.M401040200 [Abstract] [Full Text] [PDF]

Lilin Zhang, Shigeomi Shimizu, Kazuhiro Sakamaki, Shin Yonehara, and Yoshihide Tsujimoto: A Caspase-8-independent Signaling Pathway Activated by Fas Ligation Leads to Exposure of the Bak N Terminus
J. Biol. Chem. 2004 279: 33865-33874. First Published on May 24, 2004; doi:10.1074/jbc.M403499200 [Abstract] [Full Text] [PDF]

Jeffrey M. Beekman, Jantine E. Bakema, Joke van der Linden, Bastiaan Tops, Marja Hinten, Martine van Vugt, Jan G. J. van de Winkel, and Jeanette H. W. Leusen: Modulation of Fc ${gamma}$ RI (CD64) Ligand Binding by Blocking Peptides of Periplakin
J. Biol. Chem. 2004 279: 33875-33881. First Published on May 25, 2004; doi:10.1074/jbc.M401018200 [Abstract] [Full Text] [PDF]

Ingrid A. Lobo, Maria Paola Mascia, James R. Trudell, and R. Adron Harris: Channel Gating of the Glycine Receptor Changes Accessibility to Residues Implicated in Receptor Potentiation by Alcohols and Anesthetics
J. Biol. Chem. 2004 279: 33919-33927. First Published on May 28, 2004; doi:10.1074/jbc.M313941200 [Abstract] [Full Text] [PDF]

Zhixian Zhang, Thomas J. Melia, Feng He, Ching Yuan, Amy McGough, Michael F. Schmid, and Theodore G. Wensel: How a G Protein Binds a Membrane
J. Biol. Chem. 2004 279: 33937-33945. First Published on June 1, 2004; doi:10.1074/jbc.M403404200 [Abstract] [Full Text] [PDF]

Gerald E. Dodson, Yuling Shi, and Randal S. Tibbetts: DNA Replication Defects, Spontaneous DNA Damage, and ATM-dependent Checkpoint Activation in Replication Protein A-deficient Cells
J. Biol. Chem. 2004 279: 34010-34014. First Published on June 14, 2004; doi:10.1074/jbc.C400242200 [Abstract] [Full Text] [PDF] Supplemental Data

Makiko Koike, Shingo Kose, Maiko Furuta, Naoko Taniguchi, Fumihiko Yokoya, Yoshihiro Yoneda, and Naoko Imamoto: ${beta}$ -Catenin Shows an Overlapping Sequence Requirement but Distinct Molecular Interactions for Its Bidirectional Passage through Nuclear Pores
J. Biol. Chem. 2004 279: 34038-34047. First Published on June 1, 2004; doi:10.1074/jbc.M405821200 [Abstract] [Full Text] [PDF] Supplemental Data

Molecular Basis Of Cell and Developmental Biology:

Aleksandar Ivetic, Oliver Florey, Jürgen Deka, Dorian O. Haskard, Ann Ager, and Anne J. Ridley: Mutagenesis of the Ezrin-Radixin-Moesin Binding Domain of L-selectin Tail Affects Shedding, Microvillar Positioning, and Leukocyte Tethering
J. Biol. Chem. 2004 279: 33263-33272. First Published on June 3, 2004; doi:10.1074/jbc.M312212200 [Abstract] [Full Text] [PDF]

Nadège Briançon, Alain Bailly, Frédéric Clotman, Patrick Jacquemin, Frédéric P. Lemaigre, and Mary C. Weiss: Expression of the ${alpha}$ 7 Isoform of Hepatocyte Nuclear Factor (HNF) 4 Is Activated by HNF6/OC-2 and HNF1 and Repressed by HNF4 ${alpha}$ 1 in the Liver
J. Biol. Chem. 2004 279: 33398-33408. First Published on May 24, 2004; doi:10.1074/jbc.M405312200 [Abstract] [Full Text] [PDF] Supplemental Data

Goedele Maertens, Peter Cherepanov, Zeger Debyser, Yves Engelborghs, and Alan Engelman: Identification and Characterization of a Functional Nuclear Localization Signal in the HIV-1 Integrase Interactor LEDGF/p75
J. Biol. Chem. 2004 279: 33421-33429. First Published on May 25, 2004; doi:10.1074/jbc.M404700200 [Abstract] [Full Text] [PDF]

Elena G. Yarmola and Michael R. Bubb: Effects of Profilin and Thymosin ${beta}$ ₄ on the Critical Concentration of Actin Demonstrated in Vitro and in Cell Extracts with a Novel Direct Assay
J. Biol. Chem. 2004 279: 33519-33527. First Published on June 7, 2004; doi:10.1074/jbc.M404392200 [Abstract] [Full Text] [PDF]

Daisuke Kamei, Kiyofumi Yamakawa, Yui Takegoshi, Maya Mikami-Nakanishi, Yoshihito Nakatani, Sachiko Oh-ishi, Hidekazu Yasui, Yoshiaki Azuma, Noriyasu Hirasawa, Kazuo Ohuchi, Hiroshi Kawaguchi, Yukio Ishikawa, Toshiharu Ishii, Satoshi Uematsu, Shizuo Akira, Makoto Murakami, and Ichiro Kudo: Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1
J. Biol. Chem. 2004 279: 33684-33695. First Published on May 12, 2004; doi:10.1074/jbc.M400199200 [Abstract] [Full Text] [PDF]

Chao Qi, Papreddy Kashireddy, Yiwei Tony Zhu, Sambasiva M. Rao, and Yi-Jun Zhu: Null Mutation of Peroxisome Proliferator-activated Receptor-interacting Protein in Mammary Glands Causes Defective Mammopoiesis
J. Biol. Chem. 2004 279: 33696-33701. First Published on May 25, 2004; doi:10.1074/jbc.M401266200 [Abstract] [Full Text] [PDF]

Sven Diederichs, Nicole Bäumer, Ping Ji, Stephan K. Metzelder, Gregory E. Idos, Thomas Cauvet, Wenbing Wang, Maria Möller, Sarah Pierschalski, Jörg Gromoll, Mark G. Schrader, H. Phillip Koeffler, Wolfgang E. Berdel, Hubert Serve, and Carsten Müller-Tidow: Identification of Interaction Partners and Substrates of the Cyclin A1-CDK2 Complex
J. Biol. Chem. 2004 279: 33727-33741. First Published on May 24, 2004; doi:10.1074/jbc.M401708200 [Abstract] [Full Text] [PDF] Supplemental Data

Fumitaka Ichida, Riko Nishimura, Kenji Hata, Takuma Matsubara, Fumiyo Ikeda, Kunihiro Hisada, Hirofumi Yatani, Xu Cao, Toshihisa Komori, Akira Yamaguchi, and Toshiyuki Yoneda: Reciprocal Roles of Msx2 in Regulation of Osteoblast and Adipocyte Differentiation
J. Biol. Chem. 2004 279: 34015-34022. First Published on June 1, 2004; doi:10.1074/jbc.M403621200 [Abstract] [Full Text] [PDF]

Suzie Verma, Annette M. Shewan, Jeanie A. Scott, Falak M. Helwani, Nicole R. den Elzen, Hiroaki Miki, Tadaomi Takenawa, and Alpha S. Yap: Arp2/3 Activity Is Necessary for Efficient Formation of E-cadherin Adhesive Contacts
J. Biol. Chem. 2004 279: 34062-34070. First Published on May 24, 2004; doi:10.1074/jbc.M404814200 [Abstract] [Full Text] [PDF] Supplemental Data

Jing Lin, Qingyuan Yang, Zhe Yan, Joseph Markowitz, Paul T. Wilder, France Carrier, and David J. Weber: Inhibiting S100B Restores p53 Levels in Primary Malignant Melanoma Cancer Cells
J. Biol. Chem. 2004 279: 34071-34077. First Published on June 3, 2004; doi:10.1074/jbc.M405419200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Sharon Wald Krauss, Gloria Lee, Joel Anne Chasis, Narla Mohandas, and Rebecca Heald: Two protein 4.1 domains essential for mitotic spindle and aster microtubule dynamics and organization in vitro. Vol. 279 (2004) 27591–27598
J. Biol. Chem. 2004 279: 34078. [Full Text] [PDF]