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Table of Contents: Sep 17 2004; 279 (38)   [Index by Author]  [Papers Of The Week] [Cover Figure and Caption]
       Papers Of The Week
       Reflections
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Genomics, Proteomics, and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Papers Of The Week:


A Spontaneous Point Mutation Produces Monoamine Oxidase A/B Knock-out Mice with Greatly Elevated Monoamines and Anxiety-like Behavior

J. Biol. Chem. 2004 279: e99910. [Full Text] [PDF]  


Reflections:

M. Daniel Lane
The Biotin Connection: Severo Ochoa, Harland Wood, and Feodor Lynen
J. Biol. Chem. 2004 279: 39187-39194. First Published on May 27, 2004; doi:10.1074/jbc.X400005200 [Full Text] [PDF]  


Accelerated Publications:

Daria Maria Monti and Giuseppe D'Alessio
Cytosolic RNase Inhibitor Only Affects RNases with Intrinsic Cytotoxicity
J. Biol. Chem. 2004 279: 39195-39198. First Published on July 23, 2004; doi:10.1074/jbc.C400311200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:

Bokun Cheng, Jingyang Feng, Vishwaroop Mulay, Sharvari Gadgil, and Yuk-Ching Tse-Dinh
Site-directed Mutagenesis of Residues Involved in G Strand DNA Binding by Escherichia coli DNA Topoisomerase I
J. Biol. Chem. 2004 279: 39207-39213. First Published on June 23, 2004; doi:10.1074/jbc.M405891200 [Abstract] [Full Text] [PDF]  

Funda Sar, Laura A. Lindsey-Boltz, Deepa Subramanian, Deborah L. Croteau, Stephanie Q. Hutsell, Jack D. Griffith, and Aziz Sancar
Human Claspin Is a Ring-shaped DNA-binding Protein with High Affinity to Branched DNA Structures
J. Biol. Chem. 2004 279: 39289-39295. First Published on June 28, 2004; doi:10.1074/jbc.M405793200 [Abstract] [Full Text] [PDF]  

Yeturu V. R. Reddy, Qi Ding, Susan P. Lees-Miller, Katheryn Meek, and Dale A. Ramsden
Non-homologous End Joining Requires That the DNA-PK Complex Undergo an Autophosphorylation-dependent Rearrangement at DNA Ends
J. Biol. Chem. 2004 279: 39408-39413. First Published on July 15, 2004; doi:10.1074/jbc.M406432200 [Abstract] [Full Text] [PDF]  

France Léveillé, Eric Blom, Annette L. Medhurst, Patrick Bier, El Houari Laghmani, Mark Johnson, Martin A. Rooimans, Alexandra Sobeck, Quinten Waisfisz, Fré Arwert, K. J. Patel, Maureen E. Hoatlin, Hans Joenje, and Johan P. de Winter
The Fanconi Anemia Gene Product FANCF Is a Flexible Adaptor Protein
J. Biol. Chem. 2004 279: 39421-39430. First Published on July 15, 2004; doi:10.1074/jbc.M407034200 [Abstract] [Full Text] [PDF]  

Jian Wang, Timothy Wiltshire, Yutian Wang, Carmenza Mikell, Julian Burks, Cynthia Cunningham, Emily S. Van Laar, Stephen J. Waters, Eddie Reed, and Weixin Wang
ATM-dependent CHK2 Activation Induced by Anticancer Agent, Irofulven
J. Biol. Chem. 2004 279: 39584-39592. First Published on July 20, 2004; doi:10.1074/jbc.M400015200 [Abstract] [Full Text] [PDF]  

Brietta L. Pike, Nora Tenis, and Jörg Heierhorst
Rad53 Kinase Activation-independent Replication Checkpoint Function of the N-terminal Forkhead-associated (FHA1) Domain
J. Biol. Chem. 2004 279: 39636-39644. First Published on July 22, 2004; doi:10.1074/jbc.M405080200 [Abstract] [Full Text] [PDF]  

Tetsu M. C. Yung, Sachiko Sato, and Masahiko S. Satoh
Poly(ADP-ribosyl)ation as a DNA Damage-induced Post-translational Modification Regulating Poly(ADP-ribose) Polymerase-1-Topoisomerase I Interaction
J. Biol. Chem. 2004 279: 39686-39696. First Published on July 7, 2004; doi:10.1074/jbc.M402729200 [Abstract] [Full Text] [PDF]  

Ligeng Tian, Jane M. Sayer, Donald M. Jerina, and Stewart Shuman
Individual Nucleotide Bases, Not Base Pairs, Are Critical for Triggering Site-specific DNA Cleavage by Vaccinia Topoisomerase
J. Biol. Chem. 2004 279: 39718-39726. First Published on July 13, 2004; doi:10.1074/jbc.M407376200 [Abstract] [Full Text] [PDF]  

Hong-Yu Hu, Julie K. Horton, Michael R. Gryk, Rajendra Prasad, Jana M. Naron, Di-An Sun, Sidney M. Hecht, Samuel H. Wilson, and Gregory P. Mullen
Identification of Small Molecule Synthetic Inhibitors of DNA Polymerase {beta} by NMR Chemical Shift Mapping
J. Biol. Chem. 2004 279: 39736-39744. First Published on July 15, 2004; doi:10.1074/jbc.M402842200 [Abstract] [Full Text] [PDF] Supplemental Data  


Genes: Structure and Regulation:

Tobias Löfstedt, Annika Jögi, Mikael Sigvardsson, Katarina Gradin, Lorenz Poellinger, Sven Påhlman, and Håkan Axelson
Induction of ID2 Expression by Hypoxia-inducible Factor-1: A ROLE IN DEDIFFERENTIATION OF HYPOXIC NEUROBLASTOMA CELLS
J. Biol. Chem. 2004 279: 39223-39231. First Published on July 13, 2004; doi:10.1074/jbc.M402904200 [Abstract] [Full Text] [PDF]  

Zhengjian Zhang and Joseph C. Reese
Redundant Mechanisms Are Used by Ssn6-Tup1 in Repressing Chromosomal Gene Transcription in Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 39240-39250. First Published on July 14, 2004; doi:10.1074/jbc.M407159200 [Abstract] [Full Text] [PDF]  

Kevin Chen, Daniel P. Holschneider, Weihua Wu, Igor Rebrin, and Jean C. Shih
A Spontaneous Point Mutation Produces Monoamine Oxidase A/B Knock-out Mice with Greatly Elevated Monoamines and Anxiety-like Behavior
J. Biol. Chem. 2004 279: 39645-39652. First Published on July 22, 2004; doi:10.1074/jbc.M405550200 [Abstract] [Full Text] [PDF] [Papers Of The Week]  

Ralf Schwanbeck, Hua Xiao, and Carl Wu
Spatial Contacts and Nucleosome Step Movements Induced by the NURF Chromatin Remodeling Complex
J. Biol. Chem. 2004 279: 39933-39941. First Published on July 15, 2004; doi:10.1074/jbc.M406060200 [Abstract] [Full Text] [PDF] Supplemental Data  


RNA: Structure, Metabolism, and Catalysis:

Pablo Arrisi-Mercado, Maurizio Romano, Andres F. Muro, and Francisco E. Baralle
An Exonic Splicing Enhancer Offsets the Atypical GU-rich 3' Splice Site of Human Apolipoprotein A-II Exon 3
J. Biol. Chem. 2004 279: 39331-39339. First Published on July 7, 2004; doi:10.1074/jbc.M405566200 [Abstract] [Full Text] [PDF]  

Ariel Roldan, Rodney S. Russell, Bruno Marchand, Matthias Götte, Chen Liang, and Mark A. Wainberg
In Vitro Identification and Characterization of an Early Complex Linking HIV-1 Genomic RNA Recognition and Pr55Gag Multimerization
J. Biol. Chem. 2004 279: 39886-39894. First Published on July 9, 2004; doi:10.1074/jbc.M405632200 [Abstract] [Full Text] [PDF]  

HyunDae D. Cho and Alan M. Weiner
A Single Catalytically Active Subunit in the Multimeric Sulfolobus shibatae CCA-adding Enzyme Can Carry Out All Three Steps of CCA Addition
J. Biol. Chem. 2004 279: 40130-40136. First Published on July 19, 2004; doi:10.1074/jbc.M405518200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:

Tung-Liang Chung, He-Hsuan Hsiao, Yuh-Ying Yeh, Hui-Ling Shia, Yi-Ling Chen, Po-Huang Liang, Andrew H.-J. Wang, Kay-Hooi Khoo, and Steven Shoei-Lung Li
In Vitro Modification of Human Centromere Protein CENP-C Fragments by Small Ubiquitin-like Modifier (SUMO) Protein: DEFINITIVE IDENTIFICATION OF THE MODIFICATION SITES BY TANDEM MASS SPECTROMETRY ANALYSIS OF THE ISOPEPTIDES
J. Biol. Chem. 2004 279: 39653-39662. First Published on July 22, 2004; doi:10.1074/jbc.M405637200 [Abstract] [Full Text] [PDF] Supplemental Data  

Seema Chakravarthi and Neil J. Bulleid
Glutathione Is Required to Regulate the Formation of Native Disulfide Bonds within Proteins Entering the Secretory Pathway
J. Biol. Chem. 2004 279: 39872-39879. First Published on July 14, 2004; doi:10.1074/jbc.M406912200 [Abstract] [Full Text] [PDF]  

Kizhakkekara R. Santhamma, Ramkrishna Sadhukhan, Michael Kinter, Saurabh Chattopadhyay, Brian McCue, and Indira Sen
Role of Tyrosine Phosphorylation in the Regulation of Cleavage Secretion of Angiotensin-converting Enzyme
J. Biol. Chem. 2004 279: 40227-40236. First Published on July 12, 2004; doi:10.1074/jbc.M407176200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:

Nathalie Marissal-Arvy, Marc Lombès, Jessica Petterson, Marie-Pierre Moisan, and Pierre Mormède
Gain of Function Mutation in the Mineralocorticoid Receptor of the Brown Norway Rat
J. Biol. Chem. 2004 279: 39232-39239. First Published on July 12, 2004; doi:10.1074/jbc.M407436200 [Abstract] [Full Text] [PDF]  

A. Harvey Millar, Alice E. Trend, and Joshua L. Heazlewood
Changes in the Mitochondrial Proteome during the Anoxia to Air Transition in Rice Focus around Cytochrome-containing Respiratory Complexes
J. Biol. Chem. 2004 279: 39471-39478. First Published on July 16, 2004; doi:10.1074/jbc.M406015200 [Abstract] [Full Text] [PDF]  

Thuy D. Vo, Harvey J. Greenberg, and Bernhard O. Palsson
Reconstruction and Functional Characterization of the Human Mitochondrial Metabolic Network Based on Proteomic and Biochemical Data
J. Biol. Chem. 2004 279: 39532-39540. First Published on June 17, 2004; doi:10.1074/jbc.M403782200 [Abstract] [Full Text] [PDF] Supplemental Data  

Helena I. M. Boshoff, Timothy G. Myers, Brent R. Copp, Michael R. McNeil, Michael A. Wilson, and Clifton E. Barry, III
The Transcriptional Responses of Mycobacterium tuberculosis to Inhibitors of Metabolism: NOVEL INSIGHTS INTO DRUG MECHANISMS OF ACTION
J. Biol. Chem. 2004 279: 40174-40184. First Published on July 9, 2004; doi:10.1074/jbc.M406796200 [Abstract] [Full Text] [PDF] Supplemental Data  


Protein Structure and Folding:

Mauren L. Estevam, Otaciro R. Nascimento, Mauricio S. Baptista, Paolo Di Mascio, Fernanda M. Prado, Adelaide Faljoni-Alario, Maria do Rosario Zucchi, and Iseli L. Nantes
Changes in the Spin State and Reactivity of Cytochrome c Induced by Photochemically Generated Singlet Oxygen and Free Radicals
J. Biol. Chem. 2004 279: 39214-39222. First Published on July 9, 2004; doi:10.1074/jbc.M402093200 [Abstract] [Full Text] [PDF]  

Karin Nienhaus, Estelle M. Maes, Andrzej Weichsel, William R. Montfort, and G. Ulrich Nienhaus
Structural Dynamics Controls Nitric Oxide Affinity in Nitrophorin 4
J. Biol. Chem. 2004 279: 39401-39407. First Published on July 16, 2004; doi:10.1074/jbc.M406178200 [Abstract] [Full Text] [PDF]  

James D. Garrity, James M. Pauff, and Michael W. Crowder
Probing the Dynamics of a Mobile Loop above the Active Site of L1, a Metallo-{beta}-lactamase from Stenotrophomonas maltophilia, via Site-directed Mutagenesis and Stopped-flow Fluorescence Spectroscopy
J. Biol. Chem. 2004 279: 39663-39670. First Published on July 22, 2004; doi:10.1074/jbc.M406826200 [Abstract] [Full Text] [PDF]  

Vincent Beringue, Didier Vilette, Gary Mallinson, Fabienne Archer, Maria Kaisar, Mourad Tayebi, Graham S. Jackson, Anthony R. Clarke, Hubert Laude, John Collinge, and Simon Hawke
PrPSc Binding Antibodies Are Potent Inhibitors of Prion Replication in Cell Lines
J. Biol. Chem. 2004 279: 39671-39676. First Published on May 7, 2004; doi:10.1074/jbc.M402270200 [Abstract] [Full Text] [PDF]  

Farooqahmed S. Kittur, Chandrashekhara Manithody, James H. Morrissey, and Alireza R. Rezaie
The Cofactor Function of the N-terminal Domain of Tissue Factor
J. Biol. Chem. 2004 279: 39745-39749. First Published on July 13, 2004; doi:10.1074/jbc.M406628200 [Abstract] [Full Text] [PDF]  

Richard F. Collins, Stephan A. Frye, Ashraf Kitmitto, Robert C. Ford, Tone Tønjum, and Jeremy P. Derrick
Structure of the Neisseria meningitidis Outer Membrane PilQ Secretin Complex at 12 Å Resolution
J. Biol. Chem. 2004 279: 39750-39756. First Published on July 14, 2004; doi:10.1074/jbc.M405971200 [Abstract] [Full Text] [PDF]  

Raina J. Y. Simpson, Stella Hoi Yi Lee, Natalie Bartle, Eleanor Y. Sum, Jane E. Visvader, Jacqueline M. Matthews, Joel P. Mackay, and Merlin Crossley
A Classic Zinc Finger from Friend of GATA Mediates an Interaction with the Coiled-coil of Transforming Acidic Coiled-coil 3
J. Biol. Chem. 2004 279: 39789-39797. First Published on July 2, 2004; doi:10.1074/jbc.M404130200 [Abstract] [Full Text] [PDF]  

Keiko Aoki, Sohkichi Matsumoto, Yukio Hirayama, Takayuki Wada, Yuriko Ozeki, Makoto Niki, Pilar Domenech, Kiyoko Umemori, Saburo Yamamoto, Amao Mineda, Makoto Matsumoto, and Kazuo Kobayashi
Extracellular Mycobacterial DNA-binding Protein 1 Participates in Mycobacterium-Lung Epithelial Cell Interaction through Hyaluronic Acid
J. Biol. Chem. 2004 279: 39798-39806. First Published on July 2, 2004; doi:10.1074/jbc.M402677200 [Abstract] [Full Text] [PDF]  

Agustin O. Pineda, Zhi-Wei Chen, Sonia Caccia, Angelene M. Cantwell, Savvas N. Savvides, Gabriel Waksman, F. Scott Mathews, and Enrico Di Cera
The Anticoagulant Thrombin Mutant W215A/E217A Has a Collapsed Primary Specificity Pocket
J. Biol. Chem. 2004 279: 39824-39828. First Published on July 13, 2004; doi:10.1074/jbc.M407272200 [Abstract] [Full Text] [PDF]  

Kathrin Barnewitz, Chaoshe Guo, Madhumati Sevvana, Qingjun Ma, George M. Sheldrick, Hans-Dieter Söling, and David M. Ferrari
Mapping of a Substrate Binding Site in the Protein Disulfide Isomerase-related Chaperone Wind Based on Protein Function and Crystal Structure
J. Biol. Chem. 2004 279: 39829-39837. First Published on July 12, 2004; doi:10.1074/jbc.M406839200 [Abstract] [Full Text] [PDF]  

Sam M. Mazhari, Curtis T. Selser, and Christine R. Cremo
Novel Sensors of the Regulatory Switch on the Regulatory Light Chain of Smooth Muscle Myosin
J. Biol. Chem. 2004 279: 39905-39914. First Published on July 15, 2004; doi:10.1074/jbc.M407062200 [Abstract] [Full Text] [PDF]  

Thomas Prince and Robert L. Matts
Definition of Protein Kinase Sequence Motifs That Trigger High Affinity Binding of Hsp90 and Cdc37
J. Biol. Chem. 2004 279: 39975-39981. First Published on July 17, 2004; doi:10.1074/jbc.M406882200 [Abstract] [Full Text] [PDF]  

Yu Sun, Marc Mansour, Julie A. Crack, Gillian L. Gass, and Thomas H. MacRae
Oligomerization, Chaperone Activity, and Nuclear Localization of p26, a Small Heat Shock Protein from Artemia franciscana
J. Biol. Chem. 2004 279: 39999-40006. First Published on July 16, 2004; doi:10.1074/jbc.M406999200 [Abstract] [Full Text] [PDF]  

Pernille Andersen, Birthe B. Kragelund, Addie N. Olsen, Flemming H. Larsen, Nam-Hai Chua, Flemming M. Poulsen, and Karen Skriver
Structure and Biochemical Function of a Prototypical Arabidopsis U-box Domain
J. Biol. Chem. 2004 279: 40053-40061. First Published on June 30, 2004; doi:10.1074/jbc.M405057200 [Abstract] [Full Text] [PDF]  

Liqing Chen, Enrico DiGiammarino, Xiaoyin E. Zhou, Yujun Wang, Diana Toh, Thomas W. Hodge, and Edward J. Meehan
High Resolution Crystal Structure of Human Rab9 GTPase: A NOVEL ANTIVIRAL DRUG TARGET
J. Biol. Chem. 2004 279: 40204-40208. First Published on July 19, 2004; doi:10.1074/jbc.M407114200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Robert J. Sasata, Darwin W. Reed, Michèle C. Loewen, and Patrick S. Covello
Domain Swapping Localizes the Structural Determinants of Regioselectivity in Membrane-bound Fatty Acid Desaturases of Caenorhabditis elegans
J. Biol. Chem. 2004 279: 39296-39302. First Published on June 29, 2004; doi:10.1074/jbc.M405712200 [Abstract] [Full Text] [PDF]  

Razvan V. Dumitru and Stephen W. Ragsdale
Mechanism of 4-({beta}-D-Ribofuranosyl)aminobenzene 5'-Phosphate Synthase, a Key Enzyme in the Methanopterin Biosynthetic Pathway
J. Biol. Chem. 2004 279: 39389-39395. First Published on July 15, 2004; doi:10.1074/jbc.M406442200 [Abstract] [Full Text] [PDF]  

Haobo Liang, Wentian Luo, Neil Green, and Hong Fang
Cargo Sequences Are Important for Som1p-dependent Signal Peptide Cleavage in Yeast Mitochondria
J. Biol. Chem. 2004 279: 39396-39400. First Published on July 14, 2004; doi:10.1074/jbc.M406915200 [Abstract] [Full Text] [PDF]  

Semira Galijasevic, Ghassan M. Saed, Michael P. Diamond, and Husam M. Abu-Soud
High Dissociation Rate Constant of Ferrous-Dioxy Complex Linked to the Catalase-like Activity in Lactoperoxidase
J. Biol. Chem. 2004 279: 39465-39470. First Published on July 17, 2004; doi:10.1074/jbc.M406003200 [Abstract] [Full Text] [PDF]  

Xiang He and Paul R. Ortiz de Montellano
Radical Rebound Mechanism in Cytochrome P-450-catalyzed Hydroxylation of the Multifaceted Radical Clocks {alpha}- and {beta}-Thujone
J. Biol. Chem. 2004 279: 39479-39484. First Published on July 17, 2004; doi:10.1074/jbc.M406838200 [Abstract] [Full Text] [PDF]  

Sudhir Paul, Sangeeta Karle, Stephanie Planque, Hiroaki Taguchi, Maria Salas, Yasuhiro Nishiyama, Beverly Handy, Robert Hunter, Allen Edmundson, and Carl Hanson
Naturally Occurring Proteolytic Antibodies: SELECTIVE IMMUNOGLOBULIN M-CATALYZED HYDROLYSIS OF HIV gp120
J. Biol. Chem. 2004 279: 39611-39619. First Published on July 21, 2004; doi:10.1074/jbc.M406719200 [Abstract] [Full Text] [PDF]  

Emeline Aubert-Jousset, Véronique Sbarra, and Dominique Lombardo
Site-directed Mutagenesis of the Distal Basic Cluster of Pancreatic Bile Salt-dependent Lipase
J. Biol. Chem. 2004 279: 39697-39704. First Published on July 20, 2004; doi:10.1074/jbc.M407646200 [Abstract] [Full Text] [PDF]  

Supaart Sirikantaramas, Satoshi Morimoto, Yoshinari Shoyama, Yu Ishikawa, Yoshiko Wada, Yukihiro Shoyama, and Futoshi Taura
The Gene Controlling Marijuana Psychoactivity: MOLECULAR CLONING AND HETEROLOGOUS EXPRESSION OF {Delta}1-TETRAHYDROCANNABINOLIC ACID SYNTHASE FROM CANNABIS SATIVA L.
J. Biol. Chem. 2004 279: 39767-39774. First Published on June 9, 2004; doi:10.1074/jbc.M403693200 [Abstract] [Full Text] [PDF]  

Michael K. Swan, Thomas Hansen, Peter Schönheit, and Christopher Davies
A Novel Phosphoglucose Isomerase (PGI)/Phosphomannose Isomerase from the Crenarchaeon Pyrobaculum aerophilum Is a Member of the PGI Superfamily: STRUCTURAL EVIDENCE AT 1.16-Å RESOLUTION
J. Biol. Chem. 2004 279: 39838-39845. First Published on July 13, 2004; doi:10.1074/jbc.M406855200 [Abstract] [Full Text] [PDF]  

Balázs Váradi, Krasimir Kolev, Kiril Tenekedjiev, Gyöngyi Mészáros, Ilona Kovalszky, Colin Longstaff, and Raymund Machovich
Phospholipid Barrier to Fibrinolysis: ROLE FOR THE ANIONIC POLAR HEAD CHARGE AND THE GEL PHASE CRYSTALLINE STRUCTURE
J. Biol. Chem. 2004 279: 39863-39871. First Published on July 14, 2004; doi:10.1074/jbc.M405172200 [Abstract] [Full Text] [PDF]  

Steven S. Rosenfeld and H. Lee Sweeney
A Model of Myosin V Processivity
J. Biol. Chem. 2004 279: 40100-40111. First Published on July 14, 2004; doi:10.1074/jbc.M402583200 [Abstract] [Full Text] [PDF]  

Manning T. Schmidt, Brian C. Smith, Michael D. Jackson, and John M. Denu
Coenzyme Specificity of Sir2 Protein Deacetylases: IMPLICATIONS FOR PHYSIOLOGICAL REGULATION
J. Biol. Chem. 2004 279: 40122-40129. First Published on July 21, 2004; doi:10.1074/jbc.M407484200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Dirk Schneider, Stephan Berry, Thomas Volkmer, Andreas Seidler, and Matthias Rögner
PetC1 Is the Major Rieske Iron-Sulfur Protein in the Cytochrome b6f Complex of Synechocystis sp. PCC 6803
J. Biol. Chem. 2004 279: 39383-39388. First Published on July 15, 2004; doi:10.1074/jbc.M406288200 [Abstract] [Full Text] [PDF]  

Adrian J. Lambert and Martin D. Brand
Inhibitors of the Quinone-binding Site Allow Rapid Superoxide Production from Mitochondrial NADH:Ubiquinone Oxidoreductase (Complex I)
J. Biol. Chem. 2004 279: 39414-39420. First Published on July 15, 2004; doi:10.1074/jbc.M406576200 [Abstract] [Full Text] [PDF]  

Paul J. Schaeffer, Adam R. Wende, Carolyn J. Magee, Joel R. Neilson, Teresa C. Leone, Feng Chen, and Daniel P. Kelly
Calcineurin and Calcium/Calmodulin-dependent Protein Kinase Activate Distinct Metabolic Gene Regulatory Programs in Cardiac Muscle
J. Biol. Chem. 2004 279: 39593-39603. First Published on July 19, 2004; doi:10.1074/jbc.M403649200 [Abstract] [Full Text] [PDF]  

Åsa Valadi, Katarina Granath, Lena Gustafsson, and Lennart Adler
Distinct Intracellular Localization of Gpd1p and Gpd2p, the Two Yeast Isoforms of NAD+-dependent Glycerol-3-phosphate Dehydrogenase, Explains Their Different Contributions to Redox-driven Glycerol Production
J. Biol. Chem. 2004 279: 39677-39685. First Published on June 21, 2004; doi:10.1074/jbc.M403310200 [Abstract] [Full Text] [PDF]  

Ariane Schmechel, Markus Strauss, Andrea Schlicksupp, Rüdiger Pipkorn, Christian Haass, Thomas A. Bayer, and Gerd Multhaup
Human BACE Forms Dimers and Colocalizes with APP
J. Biol. Chem. 2004 279: 39710-39717. First Published on July 9, 2004; doi:10.1074/jbc.M402785200 [Abstract] [Full Text] [PDF]  

Wagner Seixas da-Silva, Armando Gómez-Puyou, Marietta Tuena de Gómez-Puyou, Rafael Moreno-Sanchez, Fernanda G. De Felice, Leopoldo de Meis, Marcus F. Oliveira, and Antonio Galina
Mitochondrial Bound Hexokinase Activity as a Preventive Antioxidant Defense: STEADY-STATE ADP FORMATION AS A REGULATORY MECHANISM OF MEMBRANE POTENTIAL AND REACTIVE OXYGEN SPECIES GENERATION IN MITOCHONDRIA
J. Biol. Chem. 2004 279: 39846-39855. First Published on July 6, 2004; doi:10.1074/jbc.M403835200 [Abstract] [Full Text] [PDF]  

Susan Wyllie, Mark L. Cunningham, and Alan H. Fairlamb
Dual Action of Antimonial Drugs on Thiol Redox Metabolism in the Human Pathogen Leishmania donovani
J. Biol. Chem. 2004 279: 39925-39932. First Published on July 13, 2004; doi:10.1074/jbc.M405635200 [Abstract] [Full Text] [PDF]  

Kristin Kee, Barbara A. Foster, Salim Merali, Debora L. Kramer, Mary L. Hensen, Paula Diegelman, Nicholas Kisiel, Slavoljub Vujcic, Richard V. Mazurchuk, and Carl W. Porter
Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice
J. Biol. Chem. 2004 279: 40076-40083. First Published on July 13, 2004; doi:10.1074/jbc.M406002200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Zhonglin Xie, Mahipal Singh, and Krishna Singh
Differential Regulation of Matrix Metalloproteinase-2 and -9 Expression and Activity in Adult Rat Cardiac Fibroblasts in Response to Interleukin-1{beta}
J. Biol. Chem. 2004 279: 39513-39519. First Published on July 21, 2004; doi:10.1074/jbc.M405844200 [Abstract] [Full Text] [PDF]  

Takeshi Sato and Kiyoshi Furukawa
Transcriptional Regulation of the Human {beta}-1,4-Galactosyltransferase V Gene in Cancer Cells: ESSENTIAL ROLE OF TRANSCRIPTION FACTOR Sp1
J. Biol. Chem. 2004 279: 39574-39583. First Published on July 19, 2004; doi:10.1074/jbc.M405805200 [Abstract] [Full Text] [PDF]  

Richard P. Hobson, Carol A. Munro, Steven Bates, Donna M. MacCallum, Jim E. Cutler, Sigrid E. M. Heinsbroek, Gordon D. Brown, Frank C. Odds, and Neil A.R. Gow
Loss of Cell Wall Mannosylphosphate in Candida albicans Does Not Influence Macrophage Recognition
J. Biol. Chem. 2004 279: 39628-39635. First Published on July 22, 2004; doi:10.1074/jbc.M405003200 [Abstract] [Full Text] [PDF]  

Christopher L. de Graffenried and Carolyn R. Bertozzi
The Stem Region of the Sulfotransferase GlcNAc6ST-1 Is a Determinant of Substrate Specificity
J. Biol. Chem. 2004 279: 40035-40043. First Published on June 25, 2004; doi:10.1074/jbc.M405709200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Gang Tian, David Wilcockson, V. Hugh Perry, Pauline M. Rudd, Raymond A. Dwek, Frances M. Platt, and Nick Platt
Inhibition of {alpha}-Glucosidases I and II Increases the Cell Surface Expression of Functional Class A Macrophage Scavenger Receptor (SR-A) by Extending Its Half-life
J. Biol. Chem. 2004 279: 39303-39309. First Published on July 2, 2004; doi:10.1074/jbc.M405219200 [Abstract] [Full Text] [PDF]  

Medha Manchekar, Paul E. Richardson, Trudy M. Forte, Geeta Datta, Jere P. Segrest, and Nassrin Dashti
Apolipoprotein B-containing Lipoprotein Particle Assembly: LIPID CAPACITY OF THE NASCENT LIPOPROTEIN PARTICLE
J. Biol. Chem. 2004 279: 39757-39766. First Published on July 14, 2004; doi:10.1074/jbc.M406302200 [Abstract] [Full Text] [PDF]  

Hidenori Miyadai, Kimie Tanaka-Masuda, Shin-ichi Matsuyama, and Hajime Tokuda
Effects of Lipoprotein Overproduction on the Induction of DegP (HtrA) Involved in Quality Control in the Escherichia coli Periplasm
J. Biol. Chem. 2004 279: 39807-39813. First Published on July 13, 2004; doi:10.1074/jbc.M406390200 [Abstract] [Full Text] [PDF]  

Ho-Jin Koh, Su-Min Lee, Byung-Gap Son, Soh-Hyun Lee, Zae Young Ryoo, Kyu-Tae Chang, Jeen-Woo Park, Dong-Chan Park, Byoung J. Song, Richard L. Veech, Hebok Song, and Tae-Lin Huh
Cytosolic NADP+-dependent Isocitrate Dehydrogenase Plays a Key Role in Lipid Metabolism
J. Biol. Chem. 2004 279: 39968-39974. First Published on July 14, 2004; doi:10.1074/jbc.M402260200 [Abstract] [Full Text] [PDF]  

Claudia Banchio, Luis M. Schang, and Dennis E. Vance
Phosphorylation of Sp1 by Cyclin-dependent Kinase 2 Modulates the Role of Sp1 in CTP:Phosphocholine Cytidylyltransferase {alpha} Regulation during the S Phase of the Cell Cycle
J. Biol. Chem. 2004 279: 40220-40226. First Published on July 9, 2004; doi:10.1074/jbc.M406468200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:

Yinan Wei, Huilin Li, and Dax Fu
Oligomeric State of the Escherichia coli Metal Transporter YiiP
J. Biol. Chem. 2004 279: 39251-39259. First Published on July 16, 2004; doi:10.1074/jbc.M407044200 [Abstract] [Full Text] [PDF]  

Liang Yi, Nil Celebi, Minyong Chen, and Ross E. Dalbey
Sec/SRP Requirements and Energetics of Membrane Insertion of Subunits a, b, and c of the Escherichia coli F1F0 ATP Synthase
J. Biol. Chem. 2004 279: 39260-39267. First Published on July 19, 2004; doi:10.1074/jbc.M405490200 [Abstract] [Full Text] [PDF]  

Susanne Nessler, Oliver Friedrich, Naziha Bakouh, Rainer H. A. Fink, Cecilia P. Sanchez, Gabrielle Planelles, and Michael Lanzer
Evidence for Activation of Endogenous Transporters in Xenopus laevis Oocytes Expressing the Plasmodium falciparum Chloroquine Resistance Transporter, PfCRT
J. Biol. Chem. 2004 279: 39438-39446. First Published on July 16, 2004; doi:10.1074/jbc.M404671200 [Abstract] [Full Text] [PDF]  

Mark W. Musch, Dana-Lynn T. Koomoa, and Leon Goldstein
Hypotonicity-induced Exocytosis of the Skate Anion Exchanger skAE1: ROLE OF LIPID RAFT REGIONS
J. Biol. Chem. 2004 279: 39447-39453. First Published on July 16, 2004; doi:10.1074/jbc.M405363200 [Abstract] [Full Text] [PDF]  

Sandra Gendreau, Stephan Voswinkel, Delany Torres-Salazar, Niklas Lang, Hannelore Heidtmann, Silvia Detro-Dassen, Günther Schmalzing, Patricia Hidalgo, and Christoph Fahlke
A Trimeric Quaternary Structure Is Conserved in Bacterial and Human Glutamate Transporters
J. Biol. Chem. 2004 279: 39505-39512. First Published on July 20, 2004; doi:10.1074/jbc.M408038200 [Abstract] [Full Text] [PDF]  

Eva Y. Chen, M. Claire Bartlett, Tip W. Loo, and David M. Clarke
The {Delta}F508 Mutation Disrupts Packing of the Transmembrane Segments of the Cystic Fibrosis Transmembrane Conductance Regulator
J. Biol. Chem. 2004 279: 39620-39627. First Published on July 21, 2004; doi:10.1074/jbc.M407887200 [Abstract] [Full Text] [PDF]  

Paul Bruinsma, Robert G. Spelbrink, and Steven F. Nothwehr
Retrograde Transport of the Mannosyltransferase Och1p to the Early Golgi Requires a Component of the COG Transport Complex
J. Biol. Chem. 2004 279: 39814-39823. First Published on June 30, 2004; doi:10.1074/jbc.M405500200 [Abstract] [Full Text] [PDF]  

Andrew R. Flannery, Laurie A. Graham, and Tom H. Stevens
Topological Characterization of the c, c', and c'' Subunits of the Vacuolar ATPase from the Yeast Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 39856-39862. First Published on July 13, 2004; doi:10.1074/jbc.M406767200 [Abstract] [Full Text] [PDF]  

Nina Kokkonen, Antti Rivinoja, Annika Kauppila, Marko Suokas, Ilmo Kellokumpu, and Sakari Kellokumpu
Defective Acidification of Intracellular Organelles Results in Aberrant Secretion of Cathepsin D in Cancer Cells
J. Biol. Chem. 2004 279: 39982-39988. First Published on July 16, 2004; doi:10.1074/jbc.M406698200 [Abstract] [Full Text] [PDF]  

Meng-Ru Shen, Ai-Chien Lin, Yueh-Mei Hsu, Tsui-Jung Chang, Ming-Jer Tang, Seth L. Alper, J. Clive Ellory, and Cheng-Yang Chou
Insulin-like Growth Factor 1 Stimulates KCl Cotransport, Which Is Necessary for Invasion and Proliferation of Cervical Cancer and Ovarian Cancer Cells
J. Biol. Chem. 2004 279: 40017-40025. First Published on July 19, 2004; doi:10.1074/jbc.M406706200 [Abstract] [Full Text] [PDF]  

Yuji Kamioka, Shigetomo Fukuhara, Hirofumi Sawa, Kazuo Nagashima, Michitaka Masuda, Michiyuki Matsuda, and Naoki Mochizuki
A Novel Dynamin-associating Molecule, Formin-binding Protein 17, Induces Tubular Membrane Invaginations and Participates in Endocytosis
J. Biol. Chem. 2004 279: 40091-40099. First Published on July 12, 2004; doi:10.1074/jbc.M404899200 [Abstract] [Full Text] [PDF] Supplemental Data  

Peter J. Mohler, Woohyun Yoon, and Vann Bennett
Ankyrin-B Targets {beta}2-Spectrin to an Intracellular Compartment in Neonatal Cardiomyocytes
J. Biol. Chem. 2004 279: 40185-40193. First Published on July 19, 2004; doi:10.1074/jbc.M406018200 [Abstract] [Full Text] [PDF] Supplemental Data  


Mechanisms Of Signal Transduction:

Gregg Banninger and Nancy C. Reich
STAT2 Nuclear Trafficking
J. Biol. Chem. 2004 279: 39199-39206. First Published on June 1, 2004; doi:10.1074/jbc.M400815200 [Abstract] [Full Text] [PDF]  

Brian M. Necela and John A. Cidlowski
A Single Amino Acid Change in the First Zinc Finger of the DNA Binding Domain of the Glucocorticoid Receptor Regulates Differential Promoter Selectivity
J. Biol. Chem. 2004 279: 39279-39288. First Published on June 25, 2004; doi:10.1074/jbc.M405489200 [Abstract] [Full Text] [PDF]  

Grace Gar-Lee Yue, Tiffany Wai-Nga Yip, Yu Huang, and Wing-Hung Ko
Cellular Mechanism for Potentiation of Ca2+-mediated Cl Secretion by the Flavonoid Baicalein in Intestinal Epithelia
J. Biol. Chem. 2004 279: 39310-39316. First Published on July 3, 2004; doi:10.1074/jbc.M406787200 [Abstract] [Full Text] [PDF]  

Jun Chen, Milan Rusnak, Robert R. Luedtke, and Anita Sidhu
D1 Dopamine Receptor Mediates Dopamine-induced Cytotoxicity via the ERK Signal Cascade
J. Biol. Chem. 2004 279: 39317-39330. First Published on July 6, 2004; doi:10.1074/jbc.M403891200 [Abstract] [Full Text] [PDF]  

Larisa E. Cybulski, Gloria del Solar, Patricio O. Craig, Manuel Espinosa, and Diego de Mendoza
Bacillus subtilis DesR Functions as a Phosphorylation-activated Switch to Control Membrane Lipid Fluidity
J. Biol. Chem. 2004 279: 39340-39347. First Published on July 9, 2004; doi:10.1074/jbc.M405150200 [Abstract] [Full Text] [PDF] Supplemental Data  

Alejandro Balbis, Gerardo Baquiran, Catherine Mounier, and Barry I. Posner
Effect of Insulin on Caveolin-enriched Membrane Domains in Rat Liver
J. Biol. Chem. 2004 279: 39348-39357. First Published on July 12, 2004; doi:10.1074/jbc.M404280200 [Abstract] [Full Text] [PDF]  

Nisha Rathore, Hittu Matta, and Preet M. Chaudhary
An Evolutionary Conserved Pathway of Nuclear Factor-{kappa}B Activation Involving Caspase-mediated Cleavage and N-end Rule Pathway-mediated Degradation of I{kappa}B{alpha}
J. Biol. Chem. 2004 279: 39358-39365. First Published on July 13, 2004; doi:10.1074/jbc.M406712200 [Abstract] [Full Text] [PDF]  

Chung Kai Wong, Wen Luo, Ying Deng, Haiying Zou, Zhiyun Ye, and Sheng-Cai Lin
The DIX Domain Protein Coiled-coil-DIX1 Inhibits c-Jun N-terminal Kinase Activation by Axin and Dishevelled through Distinct Mechanisms
J. Biol. Chem. 2004 279: 39366-39373. First Published on July 15, 2004; doi:10.1074/jbc.M404598200 [Abstract] [Full Text] [PDF]  

Tara R. Gaertner, John A. Putkey, and M. Neal Waxham
RC3/Neurogranin and Ca2+/Calmodulin-dependent Protein Kinase II Produce Opposing Effects on the Affinity of Calmodulin for Calcium
J. Biol. Chem. 2004 279: 39374-39382. First Published on July 15, 2004; doi:10.1074/jbc.M405352200 [Abstract] [Full Text] [PDF]  

Hirohito Yamaguchi, Jiandong Chen, Kapil Bhalla, and Hong-Gang Wang
Regulation of Bax Activation and Apoptotic Response to Microtubule-damaging Agents by p53 Transcription-dependent and -independent Pathways
J. Biol. Chem. 2004 279: 39431-39437. First Published on July 19, 2004; doi:10.1074/jbc.M401530200 [Abstract] [Full Text] [PDF]  

Masakatsu Yamashita, Ryo Shinnakasu, Yukiko Nigo, Motoko Kimura, Akihiro Hasegawa, Masaru Taniguchi, and Toshinori Nakayama
Interleukin (IL)-4-independent Maintenance of Histone Modification of the IL-4 Gene Loci in Memory Th2 Cells
J. Biol. Chem. 2004 279: 39454-39464. First Published on July 16, 2004; doi:10.1074/jbc.M405989200 [Abstract] [Full Text] [PDF] Supplemental Data  

David A. Brown, Jason I. E. Bruce, Stephen V. Straub, and David I. Yule
cAMP Potentiates ATP-evoked Calcium Signaling in Human Parotid Acinar Cells
J. Biol. Chem. 2004 279: 39485-39494. First Published on July 19, 2004; doi:10.1074/jbc.M406201200 [Abstract] [Full Text] [PDF]  

Dimitrios G. Zisoulis and Geoffrey S. Kansas
H-Ras and Phosphoinositide 3-Kinase Cooperate to Induce {alpha}(1,3)-Fucosyltransferase VII Expression in Jurkat T Cells
J. Biol. Chem. 2004 279: 39495-39504. First Published on July 19, 2004; doi:10.1074/jbc.M407904200 [Abstract] [Full Text] [PDF]  

Jean-François Fortin, Corinne Barat, Yannick Beauséjour, Benoit Barbeau, and Michel J. Tremblay
Hyper-responsiveness to Stimulation of Human Immunodeficiency Virus-infected CD4+ T Cells Requires Nef and Tat Virus Gene Products and Results from Higher NFAT, NF-{kappa}B, and AP-1 Induction
J. Biol. Chem. 2004 279: 39520-39531. First Published on July 16, 2004; doi:10.1074/jbc.M407477200 [Abstract] [Full Text] [PDF]  

Yasunari Takada, Xianjun Fang, Md. Saha Jamaluddin, Douglas D. Boyd, and Bharat B. Aggarwal
Genetic Deletion of Glycogen Synthase Kinase-3{beta} Abrogates Activation of I{kappa}B{alpha} Kinase, JNK, Akt, and p44/p42 MAPK but Potentiates Apoptosis Induced by Tumor Necrosis Factor
J. Biol. Chem. 2004 279: 39541-39554. First Published on July 13, 2004; doi:10.1074/jbc.M403449200 [Abstract] [Full Text] [PDF]  

Cathy V. Gunther and Donald L. Riddle
Alternative Polyadenylation Results in a Truncated daf-4 BMP Receptor That Antagonizes DAF-7-mediated Development in Caenorhabditis elegans
J. Biol. Chem. 2004 279: 39555-39564. First Published on July 14, 2004; doi:10.1074/jbc.M407602200 [Abstract] [Full Text] [PDF] Suplemental Data  

Rafael Medina, Deisy Perdomo, and José Bubis
The Hydrodynamic Properties of Dark- and Light-activated States of n-Dodecyl {beta}-D-Maltoside-solubilized Bovine Rhodopsin Support the Dimeric Structure of Both Conformations
J. Biol. Chem. 2004 279: 39565-39573. First Published on July 16, 2004; doi:10.1074/jbc.M402446200 [Abstract] [Full Text] [PDF]  

Helena Morales-Johansson, Paul Jenoe, Frank T. Cooke, and Michael N. Hall
Negative Regulation of Phosphatidylinositol 4,5-Bisphosphate Levels by the INP51-associated Proteins TAX4 and IRS4
J. Biol. Chem. 2004 279: 39604-39610. First Published on July 20, 2004; doi:10.1074/jbc.M405589200 [Abstract] [Full Text] [PDF]  

Guoli Chen, Priya Raman, Padma Bhonagiri, Andrew B. Strawbridge, Guruprasad R. Pattar, and Jeffrey S. Elmendorf
Protective Effect of Phosphatidylinositol 4,5-Bisphosphate against Cortical Filamentous Actin Loss and Insulin Resistance Induced by Sustained Exposure of 3T3-L1 Adipocytes to Insulin
J. Biol. Chem. 2004 279: 39705-39709. First Published on July 23, 2004; doi:10.1074/jbc.C400171200 [Abstract] [Full Text] [PDF]  

Nadra Nilsen, Unni Nonstad, Naseema Khan, Cathrine F. Knetter, Shizuo Akira, Anders Sundan, Terje Espevik, and Egil Lien
Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88
J. Biol. Chem. 2004 279: 39727-39735. First Published on June 9, 2004; doi:10.1074/jbc.M405027200 [Abstract] [Full Text] [PDF]  

Atef Allam, Hiroaki Niiro, Edward A. Clark, and Aaron J. Marshall
The Adaptor Protein Bam32 Regulates Rac1 Activation and Actin Remodeling through a Phosphorylation-dependent Mechanism
J. Biol. Chem. 2004 279: 39775-39782. First Published on July 9, 2004; doi:10.1074/jbc.M403367200 [Abstract] [Full Text] [PDF] Supplemental Data  

Stefania Puce, Giovanna Basile, Giorgio Bavestrello, Santina Bruzzone, Carlo Cerrano, Marco Giovine, Attilio Arillo, and Elena Zocchi
Abscisic Acid Signaling through Cyclic ADP-ribose in Hydroid Regeneration
J. Biol. Chem. 2004 279: 39783-39788. First Published on July 12, 2004; doi:10.1074/jbc.M405348200 [Abstract] [Full Text] [PDF]  

Judith E. Humphries, Michael J. Kimber, Yi-Wen Barton, Walter Hsu, Nikki J. Marks, Brett Greer, Pat Harriott, Aaron G. Maule, and Tim A. Day
Structure and Bioactivity of Neuropeptide F from the Human Parasites Schistosoma mansoni and Schistosoma japonicum
J. Biol. Chem. 2004 279: 39880-39885. First Published on June 30, 2004; doi:10.1074/jbc.M405624200 [Abstract] [Full Text] [PDF]  

Daniel Kirchhofer, Xiaoyi Yao, Mark Peek, Charles Eigenbrot, Michael T. Lipari, Karen L. Billeci, Henry R. Maun, Paul Moran, Lydia Santell, Christian Wiesmann, and Robert A. Lazarus
Structural and Functional Basis of the Serine Protease-like Hepatocyte Growth Factor {beta}-Chain in Met Binding and Signaling
J. Biol. Chem. 2004 279: 39915-39924. First Published on June 24, 2004; doi:10.1074/jbc.M404795200 [Abstract] [Full Text] [PDF]  

Hiroshi Sakaue, Wataru Ogawa, Takehiro Nakamura, Toshiyuki Mori, Kyoko Nakamura, and Masato Kasuga
Role of MAPK Phosphatase-1 (MKP-1) in Adipocyte Differentiation
J. Biol. Chem. 2004 279: 39951-39957. First Published on July 20, 2004; doi:10.1074/jbc.M407353200 [Abstract] [Full Text] [PDF]  

Michael B. Fessler, Patrick G. Arndt, S. Courtney Frasch, Jonathan G. Lieber, Christopher A. Johnson, Robert C. Murphy, Jerry A. Nick, Donna L. Bratton, Kenneth C. Malcolm, and G. Scott Worthen
Lipid Rafts Regulate Lipopolysaccharide-induced Activation of Cdc42 and Inflammatory Functions of the Human Neutrophil
J. Biol. Chem. 2004 279: 39989-39998. First Published on July 15, 2004; doi:10.1074/jbc.M401080200 [Abstract] [Full Text] [PDF]  

Matthew R. MacPherson, Suzanne M. Lohmann, and Shireen-A. Davies
Analysis of Drosophila cGMP-dependent Protein Kinases and Assessment of Their in Vivo Roles by Targeted Expression in a Renal Transporting Epithelium
J. Biol. Chem. 2004 279: 40026-40034. First Published on June 24, 2004; doi:10.1074/jbc.M405619200 [Abstract] [Full Text] [PDF]  

Seok-Hyun Kim, Kunhong Kim, Jae G. Kwagh, David T. Dicker, Meenhard Herlyn, Anil K. Rustgi, Youhai Chen, and Wafik S. El-Deiry
Death Induction by Recombinant Native TRAIL and Its Prevention by a Caspase 9 Inhibitor in Primary Human Esophageal Epithelial Cells
J. Biol. Chem. 2004 279: 40044-40052. First Published on June 28, 2004; doi:10.1074/jbc.M404541200 [Abstract] [Full Text] [PDF]  

Adilson Guilherme, Neil A. Soriano, Paul S. Furcinitti, and Michael P. Czech
Role of EHD1 and EHBP1 in Perinuclear Sorting and Insulin-regulated GLUT4 Recycling in 3T3-L1 Adipocytes
J. Biol. Chem. 2004 279: 40062-40075. First Published on July 9, 2004; doi:10.1074/jbc.M401918200 [Abstract] [Full Text] [PDF] Supplemental Data  

Rebecca A. MacCorkle and Tse-Hua Tan
Inhibition of JNK2 Disrupts Anaphase and Produces Aneuploidy in Mammalian Cells
J. Biol. Chem. 2004 279: 40112-40121. First Published on July 15, 2004; doi:10.1074/jbc.M405481200 [Abstract] [Full Text] [PDF]  

Sharmistha Majumdar, Sekar Ramachandran, and Richard A. Cerione
Perturbing the Linker Regions of the {alpha}-Subunit of Transducin: A NEW CLASS OF CONSTITUTIVELY ACTIVE GTP-BINDING PROTEINS
J. Biol. Chem. 2004 279: 40137-40145. First Published on July 22, 2004; doi:10.1074/jbc.M405420200 [Abstract] [Full Text] [PDF]  

Marc Spehr, Katlen Schwane, Jeffrey A. Riffell, Jon Barbour, Richard K. Zimmer, Eva M. Neuhaus, and Hanns Hatt
Particulate Adenylate Cyclase Plays a Key Role in Human Sperm Olfactory Receptor-mediated Chemotaxis
J. Biol. Chem. 2004 279: 40194-40203. First Published on July 22, 2004; doi:10.1074/jbc.M403913200 [Abstract] [Full Text] [PDF]  

Zhaohui Jin, Fengqin Gao, Tammy Flagg, and Xingming Deng
Tobacco-specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Promotes Functional Cooperation of Bcl2 and c-Myc through Phosphorylation in Regulating Cell Survival and Proliferation
J. Biol. Chem. 2004 279: 40209-40219. First Published on June 21, 2004; doi:10.1074/jbc.M404056200 [Abstract] [Full Text] [PDF]  

Jing Wang, Natalia Sergina, Tien C. Ko, Jiangeng Gong, and Michael G. Brattain
Autocrine and Exogenous Transforming Growth Factor {beta} Control Cell Cycle Inhibition through Pathways with Different Sensitivity
J. Biol. Chem. 2004 279: 40237-40244. First Published on July 22, 2004; doi:10.1074/jbc.M401665200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Nuria Sanvicens, Violeta Gómez-Vicente, Isabel Masip, Angel Messeguer, and Thomas G. Cotter
Oxidative Stress-induced Apoptosis in Retinal Photoreceptor Cells Is Mediated by Calpains and Caspases and Blocked by the Oxygen Radical Scavenger CR-6
J. Biol. Chem. 2004 279: 39268-39278. First Published on June 21, 2004; doi:10.1074/jbc.M402202200 [Abstract] [Full Text] [PDF]  

Weifang Shen, Daniel Chrobak, Keerthi Krishnan, H. Jeffrey Lawrence, and Corey Largman
HOXB6 Protein Is Bound to CREB-binding Protein and Represses Globin Expression in a DNA Binding-dependent, PBX Interaction-independent Process
J. Biol. Chem. 2004 279: 39895-39904. First Published on July 21, 2004; doi:10.1074/jbc.M404132200 [Abstract] [Full Text] [PDF] Suplemental Data  

Dong-Hyung Cho, Yeon-Mi Hong, Ho-June Lee, Ha-Na Woo, Jong-Ok Pyo, Tak W. Mak, and Yong-Keun Jung
Induced Inhibition of Ischemic/Hypoxic Injury by APIP, a Novel Apaf-1-interacting Protein
J. Biol. Chem. 2004 279: 39942-39950. First Published on July 15, 2004; doi:10.1074/jbc.M405747200 [Abstract] [Full Text] [PDF]  

Linda M. Ritter, Kathleen Boesze-Battaglia, Beatrice M. Tam, Orson L. Moritz, Nidhi Khattree, Shu-Chu Chen, and Andrew F. X. Goldberg
Uncoupling of Photoreceptor Peripherin/rds Fusogenic Activity from Biosynthesis, Subunit Assembly, and Targeting: A POTENTIAL MECHANISM FOR PATHOGENIC EFFECTS
J. Biol. Chem. 2004 279: 39958-39967. First Published on July 13, 2004; doi:10.1074/jbc.M403943200 [Abstract] [Full Text] [PDF]  

Ali Salim, Randall P. Nacamuli, Elise F. Morgan, Amato J. Giaccia, and Michael T. Longaker
Transient Changes in Oxygen Tension Inhibit Osteogenic Differentiation and Runx2 Expression in Osteoblasts
J. Biol. Chem. 2004 279: 40007-40016. First Published on July 19, 2004; doi:10.1074/jbc.M403715200 [Abstract] [Full Text] [PDF]  

Mami Shibata, Junko Ishii, Hiroyuki Koizumi, Norihito Shibata, Naoshi Dohmae, Koji Takio, Hideki Adachi, Masafumi Tsujimoto, and Hiroyuki Arai
Type F Scavenger Receptor SREC-I Interacts with Advillin, a Member of the Gelsolin/Villin Family, and Induces Neurite-like Outgrowth
J. Biol. Chem. 2004 279: 40084-40090. First Published on July 9, 2004; doi:10.1074/jbc.M403844200 [Abstract] [Full Text] [PDF]  

Cornel Popovici, Fabien Conchonaud, Daniel Birnbaum, and Régine Roubin
Functional Phylogeny Relates LET-756 to Fibroblast Growth Factor 9
J. Biol. Chem. 2004 279: 40146-40152. First Published on June 15, 2004; doi:10.1074/jbc.M405795200 [Abstract] [Full Text] [PDF] Supplemental Data  

Zhi Sheng, John A. Lewis, and William J. Chirico
Nuclear and Nucleolar Localization of 18-kDa Fibroblast Growth Factor-2 Is Controlled by C-terminal Signals
J. Biol. Chem. 2004 279: 40153-40160. First Published on July 9, 2004; doi:10.1074/jbc.M400123200 [Abstract] [Full Text] [PDF] Supplemental Data  

Rupesh Chaturvedi, Yulan Cheng, Mohammad Asim, Françoise I. Bussière, Hangxiu Xu, Alain P. Gobert, Amy Hacker, Robert A. Casero, Jr., and Keith T. Wilson
Induction of Polyamine Oxidase 1 by Helicobacter pylori Causes Macrophage Apoptosis by Hydrogen Peroxide Release and Mitochondrial Membrane Depolarization
J. Biol. Chem. 2004 279: 40161-40173. First Published on July 9, 2004; doi:10.1074/jbc.M401370200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Zulfiqar Ahmad and Alan E. Senior
Mutagenesis of residue {beta}-Arg-246 in the phosphate-binding subdomain of catalytic sites of Escherichia coli F1-ATPase. Vol. 279 (2004) 31505-31513
J. Biol. Chem. 2004 279: 40245. [Full Text] [PDF]  

Kaisa Lehti, Heli Valtanen, Sara A. Wickström, Jouko Lohi, and Jorma Keski-Oja
Regulation of membrane-type-1 matrix metalloproteinase activity by its cytoplasmic domain. Vol. 275 (2000) 15006-15013
J. Biol. Chem. 2004 279: 40246. [Full Text] [PDF]  


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