JBC -- Table of Contents (Nov 26 2004, 279, (48))

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Selman Waksman: the Father of Antibiotics
THE CHEMICAL NATURE OF ACTINOMYCIN, AN ANTI-MICROBIAL SUBSTANCE PRODUCED BY ACTINOMYCES ANTIBIOTICUS (Selman A. Waksman and Max Tishler J. Biol. Chem. 142, 519-528)
J. Biol. Chem. 2004 279: e7. [Full Text]

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Blacktongue and Nicotinic Acid Metabolism: Philip Handler
THE BIOCHEMICAL DEFECT IN NICOTINIC ACID DEFICIENCY (Philip Handler, W. J. Dann, and With the assistance of W. Sterry Branning, Priscilla Gray, and Beatrice Mary Morrison J. Biol. Chem. 145, 145-153)
SYNTHESIS OF NICOTINAMIDE MONONUCLEOTIDE BY HUMAN ERYTHROCYTES IN VITRO (Irwin G. Leder and Philip Handler J. Biol. Chem. 189, 889-899)
J. Biol. Chem. 2004 279: e8. [Full Text]

Minireviews:

Concetta C. DiRusso and Paul N. Black: Bacterial Long Chain Fatty Acid Transport: Gateway to a Fatty Acid-responsive Signaling System
J. Biol. Chem. 2004 279: 49563-49566. First Published on August 30, 2004; doi:10.1074/jbc.R400026200 [Full Text] [PDF]

Accelerated Publications:

Madhavan R. Buddha, Tao Tao, Ronald J. Parry, and Brian R. Crane: Regioselective Nitration of Tryptophan by a Complex between Bacterial Nitric-oxide Synthase and Tryptophanyl-tRNA Synthetase
J. Biol. Chem. 2004 279: 49567-49570. First Published on October 5, 2004; doi:10.1074/jbc.C400418200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Holger Buss, Anneke Dörrie, M. Lienhard Schmitz, Ronald Frank, Mark Livingstone, Klaus Resch, and Michael Kracht: Phosphorylation of Serine 468 by GSK-3 ${beta}$ Negatively Regulates Basal p65 NF- ${kappa}$ B Activity
J. Biol. Chem. 2004 279: 49571-49574. First Published on October 1, 2004; doi:10.1074/jbc.C400442200 [Abstract] [Full Text] [PDF]

Mari Enoksson, John D. Robertson, Vladimir Gogvadze, Pengli Bu, Andrey Kropotov, Boris Zhivotovsky, and Sten Orrenius: Caspase-2 Permeabilizes the Outer Mitochondrial Membrane and Disrupts the Binding of Cytochrome c to Anionic Phospholipids
J. Biol. Chem. 2004 279: 49575-49578. First Published on October 8, 2004; doi:10.1074/jbc.C400374200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Akiko Kumagai, Soo-Mi Kim, and William G. Dunphy: Claspin and the Activated Form of ATR-ATRIP Collaborate in the Activation of Chk1
J. Biol. Chem. 2004 279: 49599-49608. First Published on September 15, 2004; doi:10.1074/jbc.M408353200 [Abstract] [Full Text] [PDF]

Spencer J. Collis, Julie M. Schwaninger, Alfred J. Ntambi, Thomas W. Keller, William G. Nelson, Larry E. Dillehay, and Theodore L. DeWeese: Evasion of Early Cellular Response Mechanisms following Low Level Radiation-induced DNA Damage
J. Biol. Chem. 2004 279: 49624-49632. First Published on September 17, 2004; doi:10.1074/jbc.M409600200 [Abstract] [Full Text] [PDF]

Siddamadappa Chandrashekaran, Matheshwaran Saravanan, Deshpande R. Radha, and Valakunja Nagaraja: Ca²+-mediated Site-specific DNA Cleavage and Suppression of Promiscuous Activity of KpnI Restriction Endonuclease
J. Biol. Chem. 2004 279: 49736-49740. First Published on September 16, 2004; doi:10.1074/jbc.M409483200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Daniel Muñoz-Espín, Mauricio G. Mateu, Laurentino Villar, Anabel Marina, Margarita Salas, and Wilfried J. J. Meijer: Phage ${varphi}$ 29 DNA Replication Organizer Membrane Protein p16.7 Contains a Coiled Coil and a Dimeric, Homeodomain-related, Functional Domain
J. Biol. Chem. 2004 279: 50437-50445. First Published on September 14, 2004; doi:10.1074/jbc.M403297200 [Abstract] [Full Text] [PDF]

Miran Yoon-Robarts, Amanda G. Blouin, Svenja Bleker, Jürgen A. Kleinschmidt, Aneel K. Aggarwal, Carlos R. Escalante, and R. Michael Linden: Residues within the B' Motif Are Critical for DNA Binding by the Superfamily 3 Helicase Rep40 of Adeno-associated Virus Type 2
J. Biol. Chem. 2004 279: 50472-50481. First Published on September 14, 2004; doi:10.1074/jbc.M403900200 [Abstract] [Full Text] [PDF]

Nathalie Andraos, Stanley Tabor, and Charles C. Richardson: The Highly Processive DNA Polymerase of Bacteriophage T5: ROLE OF THE UNIQUE N AND C TERMINI
J. Biol. Chem. 2004 279: 50609-50618. First Published on September 17, 2004; doi:10.1074/jbc.M408428200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genes: Structure and Regulation:

Brian K. Coombes, Nat F. Brown, Yanet Valdez, John H. Brumell, and B. Brett Finlay: Expression and Secretion of Salmonella Pathogenicity Island-2 Virulence Genes in Response to Acidification Exhibit Differential Requirements of a Functional Type III Secretion Apparatus and SsaL
J. Biol. Chem. 2004 279: 49804-49815. First Published on September 20, 2004; doi:10.1074/jbc.M404299200 [Abstract] [Full Text] [PDF]

Jeong Hoon Kim and Michael R. Stallcup: Role of the Coiled-coil Coactivator (CoCoA) in Aryl Hydrocarbon Receptor-mediated Transcription
J. Biol. Chem. 2004 279: 49842-49848. First Published on September 20, 2004; doi:10.1074/jbc.M408535200 [Abstract] [Full Text] [PDF]

Sergey Belikov, Per-Henrik Holmqvist, Carolina Åstrand, and Örjan Wrange: Nuclear Factor 1 and Octamer Transcription Factor 1 Binding Preset the Chromatin Structure of the Mouse Mammary Tumor Virus Promoter for Hormone Induction
J. Biol. Chem. 2004 279: 49857-49867. First Published on September 20, 2004; doi:10.1074/jbc.M409713200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Huafang Shi, Elisabetta Ullu, and Christian Tschudi: Function of the Trypanosome Argonaute 1 Protein in RNA Interference Requires the N-terminal RGG Domain and Arginine 735 in the Piwi Domain
J. Biol. Chem. 2004 279: 49889-49893. First Published on September 21, 2004; doi:10.1074/jbc.M409280200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Stelian M. Pop, Ryan J. Kolarik, and Stephen W. Ragsdale: Regulation of Anaerobic Dehalorespiration by the Transcriptional Activator CprK
J. Biol. Chem. 2004 279: 49910-49918. First Published on September 20, 2004; doi:10.1074/jbc.M409435200 [Abstract] [Full Text] [PDF]

Tim J. Viney, Thomas W. Schmidt, William Gierasch, A. Wahed Sattar, Ryan E. Yaggie, Adisa Kuburas, John P. Quinn, Judy M. Coulson, and Andrew F. Russo: Regulation of the Cell-specific Calcitonin/Calcitonin Gene-related Peptide Enhancer by USF and the Foxa2 Forkhead Protein
J. Biol. Chem. 2004 279: 49948-49955. First Published on September 22, 2004; doi:10.1074/jbc.M406659200 [Abstract] [Full Text] [PDF]

Gilles A. Robichaud, Michel Nardini, Mark Laflamme, Miroslava Cuperlovic-Culf, and Rodney J. Ouellette: Human Pax-5 C-terminal Isoforms Possess Distinct Transactivation Properties and Are Differentially Modulated in Normal and Malignant B Cells
J. Biol. Chem. 2004 279: 49956-49963. First Published on September 22, 2004; doi:10.1074/jbc.M407171200 [Abstract] [Full Text] [PDF]

Roy Auty, Hanno Steen, Lawrence C. Myers, Jim Persinger, Blaine Bartholomew, Steven P. Gygi, and Stephen Buratowski: Purification of Active TFIID from Saccharomyces cerevisiae: EXTENSIVE PROMOTER CONTACTS AND CO-ACTIVATOR FUNCTION
J. Biol. Chem. 2004 279: 49973-49981. First Published on September 22, 2004; doi:10.1074/jbc.M409849200 [Abstract] [Full Text] [PDF]

Jennifer Wessells, Mark Baer, Howard A. Young, Estefania Claudio, Keith Brown, Ulrich Siebenlist, and Peter F. Johnson: BCL-3 and NF- ${kappa}$ B p50 Attenuate Lipopolysaccharide-induced Inflammatory Responses in Macrophages
J. Biol. Chem. 2004 279: 49995-50003. First Published on October 1, 2004; doi:10.1074/jbc.M404246200 [Abstract] [Full Text] [PDF]

Ping Liao, Dejie Yu, Songqing Lu, Zhenzhi Tang, Mui Cheng Liang, Shihui Zeng, Weiming Lin, and Tuck Wah Soong: Smooth Muscle-selective Alternatively Spliced Exon Generates Functional Variation in Ca_v1.2 Calcium Channels
J. Biol. Chem. 2004 279: 50329-50335. First Published on September 20, 2004; doi:10.1074/jbc.M409436200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Karen F. Vieira, Padraic P. Levings, Meredith A. Hill, Valerie J. Crusselle, Sung-Hae Lee Kang, James Douglas Engel, and Jörg Bungert: Recruitment of Transcription Complexes to the ${beta}$ -Globin Gene Locus in Vivo and in Vitro
J. Biol. Chem. 2004 279: 50350-50357. First Published on September 22, 2004; doi:10.1074/jbc.M408883200 [Abstract] [Full Text] [PDF]

Mami Kurosaki, Mineko Terao, Maria Monica Barzago, Antonio Bastone, Davide Bernardinello, Mario Salmona, and Enrico Garattini: The Aldehyde Oxidase Gene Cluster in Mice and Rats: ALDEHYDE OXIDASE HOMOLOGUE 3, A NOVEL MEMBER OF THE MOLYBDO-FLAVOENZYME FAMILY WITH SELECTIVE EXPRESSION IN THE OLFACTORY MUCOSA
J. Biol. Chem. 2004 279: 50482-50498. First Published on September 20, 2004; doi:10.1074/jbc.M408734200 [Abstract] [Full Text] [PDF]

Takashi Minami, Keiko Horiuchi, Mai Miura, Md. Ruhul Abid, Wakako Takabe, Noriko Noguchi, Takahide Kohro, Xijin Ge, Hiroyuki Aburatani, Takao Hamakubo, Tatsuhiko Kodama, and William C. Aird: Vascular Endothelial Growth Factor- and Thrombin-induced Termination Factor, Down Syndrome Critical Region-1, Attenuates Endothelial Cell Proliferation and Angiogenesis
J. Biol. Chem. 2004 279: 50537-50554. First Published on September 23, 2004; doi:10.1074/jbc.M406454200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Lisa Y. Zhao, Jilin Liu, Gurjit S. Sidhu, Yuxin Niu, Yue Liu, Ruipeng Wang, and Daiqing Liao: Negative Regulation of p53 Functions by Daxx and the Involvement of MDM2
J. Biol. Chem. 2004 279: 50566-50579. First Published on September 10, 2004; doi:10.1074/jbc.M406743200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Amar Thyagarajan and Ben G. Szaro: Phylogenetically Conserved Binding of Specific K Homology Domain Proteins to the 3'-Untranslated Region of the Vertebrate Middle Neurofilament mRNA
J. Biol. Chem. 2004 279: 49680-49688. First Published on September 9, 2004; doi:10.1074/jbc.M408915200 [Abstract] [Full Text] [PDF]

Andrea Újvári and Donal S. Luse: Newly Initiated RNA Encounters a Factor Involved in Splicing Immediately upon Emerging from within RNA Polymerase II
J. Biol. Chem. 2004 279: 49773-49779. First Published on September 17, 2004; doi:10.1074/jbc.M409087200 [Abstract] [Full Text] [PDF]

Sven Horke, Kerstin Reumann, Christian Schulze, Frank Grosse, and Tilman Heise: The La Motif and the RNA Recognition Motifs of Human La Autoantigen Contribute Individually to RNA Recognition and Subcellular Localization
J. Biol. Chem. 2004 279: 50302-50309. First Published on September 15, 2004; doi:10.1074/jbc.M407504200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Chingakham Ranjit Singh, Yasufumi Yamamoto, and Katsura Asano: Physical Association of Eukaryotic Initiation Factor (eIF) 5 Carboxyl-terminal Domain with the Lysine-rich eIF2 ${beta}$ Segment Strongly Enhances Its Binding to eIF3
J. Biol. Chem. 2004 279: 49644-49655. First Published on September 17, 2004; doi:10.1074/jbc.M409609200 [Abstract] [Full Text] [PDF]

Huei-Lin Tang, Lu-Shu Yeh, Nian-Ku Chen, Tracy Ripmaster, Paul Schimmel, and Chien-Chia Wang: Translation of a Yeast Mitochondrial tRNA Synthetase Initiated at Redundant non-AUG Codons
J. Biol. Chem. 2004 279: 49656-49663. First Published on September 8, 2004; doi:10.1074/jbc.M408081200 [Abstract] [Full Text] [PDF]

Kunio Nakatsukasa, Shigeo Okada, Kyohei Umebayashi, Ryoichi Fukuda, Shuh-ichi Nishikawa, and Toshiya Endo: Roles of O-Mannosylation of Aberrant Proteins in Reduction of the Load for Endoplasmic Reticulum Chaperones in Yeast
J. Biol. Chem. 2004 279: 49762-49772. First Published on September 17, 2004; doi:10.1074/jbc.M403234200 [Abstract] [Full Text] [PDF]

Ruoyu Xiao, Bonney Wilkinson, Anton Solovyov, Jakob R. Winther, Arne Holmgren, Johanna Lundström-Ljung, and Hiram F. Gilbert: The Contributions of Protein Disulfide Isomerase and Its Homologues to Oxidative Protein Folding in the Yeast Endoplasmic Reticulum
J. Biol. Chem. 2004 279: 49780-49786. First Published on September 17, 2004; doi:10.1074/jbc.M409210200 [Abstract] [Full Text] [PDF]

Mary Truscott, Lelia Raynal, Yufa Wang, Ginette Bérubé, Lam Leduy, and Alain Nepveu: The N-terminal Region of the CCAAT Displacement Protein (CDP)/Cux Transcription Factor Functions as an Autoinhibitory Domain that Modulates DNA Binding
J. Biol. Chem. 2004 279: 49787-49794. First Published on September 17, 2004; doi:10.1074/jbc.M409484200 [Abstract] [Full Text] [PDF]

Ruhi Ahmed and Roger F. Duncan: Translational Regulation of Hsp90 mRNA: AUG-PROXIMAL 5'-UNTRANSLATED REGION ELEMENTS ESSENTIAL FOR PREFERENTIAL HEAT SHOCK TRANSLATION
J. Biol. Chem. 2004 279: 49919-49930. First Published on September 3, 2004; doi:10.1074/jbc.M404681200 [Abstract] [Full Text] [PDF]

Patrizia Fanara, Scott Turner, Robert Busch, Salena Killion, Mohamad Awada, Holly Turner, Ablatt Mahsut, Kristen L. LaPrade, Julie M. Stark, and Marc K. Hellerstein: In Vivo Measurement of Microtubule Dynamics Using Stable Isotope Labeling with Heavy Water: EFFECT OF TAXANES
J. Biol. Chem. 2004 279: 49940-49947. First Published on September 21, 2004; doi:10.1074/jbc.M409660200 [Abstract] [Full Text] [PDF]

Angie R. Purvis and J. Evan Sadler: A Covalent Oxidoreductase Intermediate in Propeptide-dependent von Willebrand Factor Multimerization
J. Biol. Chem. 2004 279: 49982-49988. First Published on September 22, 2004; doi:10.1074/jbc.M408727200 [Abstract] [Full Text] [PDF]

Lana E. Hanford, Jan J. Enghild, Zuzana Valnickova, Steen V. Petersen, Lisa M. Schaefer, Todd M. Schaefer, Todd A. Reinhart, and Tim D. Oury: Purification and Characterization of Mouse Soluble Receptor for Advanced Glycation End Products (sRAGE)
J. Biol. Chem. 2004 279: 50019-50024. First Published on September 20, 2004; doi:10.1074/jbc.M409782200 [Abstract] [Full Text] [PDF]

Edward Leithe and Edgar Rivedal: Ubiquitination and Down-regulation of Gap Junction Protein Connexin-43 in Response to 12-O-Tetradecanoylphorbol 13-Acetate Treatment
J. Biol. Chem. 2004 279: 50089-50096. First Published on September 14, 2004; doi:10.1074/jbc.M402006200 [Abstract] [Full Text] [PDF]

Robert Thai, Gervaise Moine, Michel Desmadril, Denis Servent, Jean-Luc Tarride, André Ménez, and Michel Léonetti: Antigen Stability Controls Antigen Presentation
J. Biol. Chem. 2004 279: 50257-50266. First Published on September 10, 2004; doi:10.1074/jbc.M405738200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Rujun Kang, Richard Swayze, Marie France Lise, Kimberly Gerrow, Asher Mullard, William G. Honer, and Alaa El-Husseini: Presynaptic Trafficking of Synaptotagmin I Is Regulated by Protein Palmitoylation
J. Biol. Chem. 2004 279: 50524-50536. First Published on September 7, 2004; doi:10.1074/jbc.M404981200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genomics, Proteomics, and Bioinformatics:

Dirk Daelemans, Sylvain V. Costes, Edward H. Cho, Rebecca A. Erwin-Cohen, Stephen Lockett, and George N. Pavlakis: In Vivo HIV-1 Rev Multimerization in the Nucleolus and Cytoplasm Identified by Fluorescence Resonance Energy Transfer
J. Biol. Chem. 2004 279: 50167-50175. First Published on August 3, 2004; doi:10.1074/jbc.M407713200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Aldrin V. Gomes, Gayathri Venkatraman, Jonathan P. Davis, Svetlana B. Tikunova, Patti Engel, R. John Solaro, and James D. Potter: Cardiac Troponin T Isoforms Affect the Ca²+ Sensitivity of Force Development in the Presence of Slow Skeletal Troponin I: INSIGHTS INTO THE ROLE OF TROPONIN T ISOFORMS IN THE FETAL HEART
J. Biol. Chem. 2004 279: 49579-49587. First Published on September 9, 2004; doi:10.1074/jbc.M407340200 [Abstract] [Full Text] [PDF]

Roland M. Bruderer, Catherine Brasseur, and Hemmo H. Meyer: The AAA ATPase p97/VCP Interacts with Its Alternative Co-factors, Ufd1-Npl4 and p47, through a Common Bipartite Binding Mechanism
J. Biol. Chem. 2004 279: 49609-49616. First Published on September 15, 2004; doi:10.1074/jbc.M408695200 [Abstract] [Full Text] [PDF]

Mihaela Necula and Jeff Kuret: Pseudophosphorylation and Glycation of Tau Protein Enhance but Do Not Trigger Fibrillization in Vitro
J. Biol. Chem. 2004 279: 49694-49703. First Published on September 10, 2004; doi:10.1074/jbc.M405527200 [Abstract] [Full Text] [PDF]

M. Francisca Olmo-Mira, Mónica Gavira, David J. Richardson, Francisco Castillo, Conrado Moreno-Vivián, and M. Dolores Roldán: NapF Is a Cytoplasmic Iron-Sulfur Protein Required for Fe-S Cluster Assembly in the Periplasmic Nitrate Reductase
J. Biol. Chem. 2004 279: 49727-49735. First Published on September 15, 2004; doi:10.1074/jbc.M406502200 [Abstract] [Full Text] [PDF]

Ines Benzaghou, Isabelle Bougie, and Martin Bisaillon: Effect of Metal Ion Binding on the Structural Stability of the Hepatitis C Virus RNA Polymerase
J. Biol. Chem. 2004 279: 49755-49761. First Published on September 15, 2004; doi:10.1074/jbc.M409657200 [Abstract] [Full Text] [PDF]

Guiomar Solanas, Susana Miravet, David Casagolda, Julio Castaño, Imma Raurell, Ana Corrionero, Antonio García de Herreros, and Mireia Duñach: ${beta}$ -Catenin and Plakoglobin N- and C-tails Determine Ligand Specificity
J. Biol. Chem. 2004 279: 49849-49856. First Published on September 20, 2004; doi:10.1074/jbc.M408685200 [Abstract] [Full Text] [PDF] [Supplemental Datac]

Aivar Lookene, Liyan Zhang, Magnus Hultin, and Gunilla Olivecrona: Rapid Subunit Exchange in Dimeric Lipoprotein Lipase and Properties of the Inactive Monomer
J. Biol. Chem. 2004 279: 49964-49972. First Published on September 22, 2004; doi:10.1074/jbc.M407419200 [Abstract] [Full Text] [PDF]

Ming Bai, Jun-Mei Zhou, and Sarah Perrett: The Yeast Prion Protein Ure2 Shows Glutathione Peroxidase Activity in Both Native and Fibrillar Forms
J. Biol. Chem. 2004 279: 50025-50030. First Published on September 15, 2004; doi:10.1074/jbc.M406612200 [Abstract] [Full Text] [PDF]

Kumiko Shiozawa, Nobuo Maita, Kentaro Tomii, Azusa Seto, Natsuko Goda, Yutaka Akiyama, Toshiyuki Shimizu, Masahiro Shirakawa, and Hidekazu Hiroaki: Structure of the N-terminal Domain of PEX1 AAA-ATPase: CHARACTERIZATION OF A PUTATIVE ADAPTOR-BINDING DOMAIN
J. Biol. Chem. 2004 279: 50060-50068. First Published on August 24, 2004; doi:10.1074/jbc.M407837200 [Abstract] [Full Text] [PDF]

Benedicta N. Nukuna, Marc S. Penn, Vernon E. Anderson, and Stanley L. Hazen: Latency and Substrate Binding Globally Reduce Solvent Accessibility of Plasminogen Activator Inhibitor Type 1 (PAI-1): AN ADAPTATION OF PAI-1 CONFORMER CRYSTAL STRUCTURES BY HYDROGEN-DEUTERIUM EXCHANGE
J. Biol. Chem. 2004 279: 50132-50141. First Published on August 26, 2004; doi:10.1074/jbc.M407548200 [Abstract] [Full Text] [PDF]

Franca Rossi, Qian Han, Junsuo Li, Jianyong Li, and Menico Rizzi: Crystal Structure of Human Kynurenine Aminotransferase I
J. Biol. Chem. 2004 279: 50214-50220. First Published on September 10, 2004; doi:10.1074/jbc.M409291200 [Abstract] [Full Text] [PDF]

Uffe B. Westergaard, Esben S. Sørensen, Guido Hermey, Morten S. Nielsen, Anders Nykjær, Kirstine Kirkegaard, Christian Jacobsen, Jørgen Gliemann, Peder Madsen, and Claus Munck Petersen: Functional Organization of the Sortilin Vps10p Domain
J. Biol. Chem. 2004 279: 50221-50229. First Published on September 10, 2004; doi:10.1074/jbc.M408873200 [Abstract] [Full Text] [PDF]

Gerald W. Hsu, James R. Kiefer, Dominique Burnouf, Olivier J. Becherel, Robert P. P. Fuchs, and Lorena S. Beese: Observing Translesion Synthesis of an Aromatic Amine DNA Adduct by a High-fidelity DNA Polymerase
J. Biol. Chem. 2004 279: 50280-50285. First Published on September 22, 2004; doi:10.1074/jbc.M409224200 [Abstract] [Full Text] [PDF]

Lodovica Loschi, Stephen J. Brokx, Tanya L. Hills, Glen Zhang, Michela G. Bertero, Andrew L. Lovering, Joel H. Weiner, and Natalie C. J. Strynadka: Structural and Biochemical Identification of a Novel Bacterial Oxidoreductase
J. Biol. Chem. 2004 279: 50391-50400. First Published on September 7, 2004; doi:10.1074/jbc.M408876200 [Abstract] [Full Text] [PDF]

Zhang-Bao Xu, Divya Chaudhary, Stephane Olland, Scott Wolfrom, Robert Czerwinski, Karl Malakian, Laura Lin, Mark L. Stahl, Diane Joseph-McCarthy, Christina Benander, Lori Fitz, Rita Greco, William S. Somers, and Lidia Mosyak: Catalytic Domain Crystal Structure of Protein Kinase C- ${theta}$ (PKC ${theta}$ )
J. Biol. Chem. 2004 279: 50401-50409. First Published on September 13, 2004; doi:10.1074/jbc.M409216200 [Abstract] [Full Text] [PDF] [Summary]

Jyung-Hurng Liu, Tsai-Wang Chang, Cheng-Yang Huang, Sue-Une Chen, Huey-Nan Wu, Ming-Chung Chang, and Chwan-Deng Hsiao: Crystal Structure of PriB, a Primosomal DNA Replication Protein of Escherichia coli
J. Biol. Chem. 2004 279: 50465-50471. First Published on September 21, 2004; doi:10.1074/jbc.M406773200 [Abstract] [Full Text] [PDF]

Lan Xu, Chenglong Li, Arthur J. Olson, and Ian A. Wilson: Crystal Structure of Avian Aminoimidazole-4-carboxamide Ribonucleotide Transformylase in Complex with a Novel Non-folate Inhibitor Identified by Virtual Ligand Screening
J. Biol. Chem. 2004 279: 50555-50565. First Published on September 7, 2004; doi:10.1074/jbc.M406801200 [Abstract] [Full Text] [PDF]

Takako Mukai, Shigeyuki Kawai, Shigetarou Mori, Bunzo Mikami, and Kousaku Murata: Crystal Structure of Bacterial Inorganic Polyphosphate/ATP-glucomannokinase: INSIGHTS INTO KINASE EVOLUTION
J. Biol. Chem. 2004 279: 50591-50600. First Published on September 17, 2004; doi:10.1074/jbc.M408126200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Bruno Mesmin, Karine Robbe, Blandine Geny, Frédéric Luton, Gérard Brandolin, Michel R. Popoff, and Bruno Antonny: A Phosphatidylserine-binding Site in the Cytosolic Fragment of Clostridium sordellii Lethal Toxin Facilitates Glucosylation of Membrane-bound Rac and Is Required for Cytotoxicity
J. Biol. Chem. 2004 279: 49876-49882. First Published on September 21, 2004; doi:10.1074/jbc.M406903200 [Abstract] [Full Text] [PDF]

Ernst G. Malygin, Bianca Sclavi, Victor V. Zinoviev, Alexey A. Evdokimov, Stanley Hattman, and Malcolm Buckle: Bacteriophage T4Dam DNA-(Adenine-N⁶)-methyltransferase: COMPARISON OF PRE-STEADY STATE AND SINGLE TURNOVER METHYLATION OF 40-MER DUPLEXES CONTAINING TWO (UN)MODIFIED TARGET SITES
J. Biol. Chem. 2004 279: 50012-50018. First Published on September 16, 2004; doi:10.1074/jbc.M409786200 [Abstract] [Full Text] [PDF]

Seong-Jun Kim, Jung-Hee Kim, Yeon-Gu Kim, Ho-Soo Lim, and Jong-Won Oh: Protein Kinase C-related Kinase 2 Regulates Hepatitis C Virus RNA Polymerase Function by Phosphorylation
J. Biol. Chem. 2004 279: 50031-50041. First Published on September 13, 2004; doi:10.1074/jbc.M408617200 [Abstract] [Full Text] [PDF]

Adesh Kumar Saini, Kapil Maithal, Prem Chand, Shantanu Chowdhury, Reena Vohra, Anita Goyal, Gyanendra P. Dubey, Puneet Chopra, Ramesh Chandra, Anil K. Tyagi, Yogendra Singh, and Vibha Tandon: Nuclear Localization and in Situ DNA Damage by Mycobacterium tuberculosis Nucleoside-diphosphate Kinase
J. Biol. Chem. 2004 279: 50142-50149. First Published on September 17, 2004; doi:10.1074/jbc.M409944200 [Abstract] [Full Text] [PDF]

Luis A. Ralat and Roberta F. Colman: Glutathione S-Transferase Pi Has at Least Three Distinguishable Xenobiotic Substrate Sites Close to Its Glutathione-binding Site
J. Biol. Chem. 2004 279: 50204-50213. First Published on September 3, 2004; doi:10.1074/jbc.M407445200 [Abstract] [Full Text] [PDF]

Alexander R. Moise, Vladimir Kuksa, Yoshikazu Imanishi, and Krzysztof Palczewski: Identification of All-trans-Retinol:All-trans-13,14-dihydroretinol Saturase
J. Biol. Chem. 2004 279: 50230-50242. First Published on September 9, 2004; doi:10.1074/jbc.M409130200 [Abstract] [Full Text] [PDF]

Denis O'Keeffe, Steven T. Olson, Nijole Gasiunas, John Gallagher, Trevor P. Baglin, and James A. Huntington: The Heparin Binding Properties of Heparin Cofactor II Suggest an Antithrombin-like Activation Mechanism
J. Biol. Chem. 2004 279: 50267-50273. First Published on September 15, 2004; doi:10.1074/jbc.M408774200 [Abstract] [Full Text] [PDF]

Hyung Jun Ahn, Kyoung Hoon Kim, Jiah Lee, Jun-Yong Ha, Hyung Ho Lee, Dojin Kim, Hye-Jin Yoon, Ae-Ran Kwon, and Se Won Suh: Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily
J. Biol. Chem. 2004 279: 50505-50513. First Published on September 7, 2004; doi:10.1074/jbc.M409246200 [Abstract] [Full Text] [PDF]

Hyung Ho Lee, Do Jin Kim, Hyung Jun Ahn, Jun Yong Ha, and Se Won Suh: Crystal Structure of T-protein of the Glycine Cleavage System: COFACTOR BINDING, INSIGHTS INTO H-PROTEIN RECOGNITION, AND MOLECULAR BASIS FOR UNDERSTANDING NONKETOTIC HYPERGLYCINEMIA
J. Biol. Chem. 2004 279: 50514-50523. First Published on September 7, 2004; doi:10.1074/jbc.M409672200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Roger Gutiérrez-Juárez, Silvana Obici, and Luciano Rossetti: Melanocortin-independent Effects of Leptin on Hepatic Glucose Fluxes
J. Biol. Chem. 2004 279: 49704-49715. First Published on September 10, 2004; doi:10.1074/jbc.M408665200 [Abstract] [Full Text] [PDF]

Mario H. Barros, Brian Bandy, Erich B. Tahara, and Alicia J. Kowaltowski: Higher Respiratory Activity Decreases Mitochondrial Reactive Oxygen Release and Increases Life Span in Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 49883-49888. First Published on September 21, 2004; doi:10.1074/jbc.M408918200 [Abstract] [Full Text] [PDF]

Christine Schönfeld, Lutz Wobbe, Rüdiger Borgstädt, Alexandra Kienast, Peter J. Nixon, and Olaf Kruse: The Nucleus-encoded Protein MOC1 Is Essential for Mitochondrial Light Acclimation in Chlamydomonas reinhardtii
J. Biol. Chem. 2004 279: 50366-50374. First Published on September 23, 2004; doi:10.1074/jbc.M408477200 [Abstract] [Full Text] [PDF]

Jeffrey S. Armstrong, Hongyuan Yang, Wei Duan, and Matthew Whiteman: Cytochrome bc₁ Regulates the Mitochondrial Permeability Transition by Two Distinct Pathways
J. Biol. Chem. 2004 279: 50420-50428. First Published on September 10, 2004; doi:10.1074/jbc.M408882200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Katharina Paschinger, Dubravko Rendic, Günter Lochnit, Verena Jantsch, and Iain B. H. Wilson: Molecular Basis of Anti-horseradish Peroxidase Staining in Caenorhabditis elegans
J. Biol. Chem. 2004 279: 49588-49598. First Published on September 13, 2004; doi:10.1074/jbc.M408978200 [Abstract] [Full Text] [PDF]

Santosh K. Patnaik, Barry Potvin, and Pamela Stanley: LEC12 and LEC29 Gain-of-Function Chinese Hamster Ovary Mutants Reveal Mechanisms for Regulating VIM-2 Antigen Synthesis and E-selectin Binding
J. Biol. Chem. 2004 279: 49716-49726. First Published on September 13, 2004; doi:10.1074/jbc.M408755200 [Abstract] [Full Text] [PDF]

Laure Garrigue-Antar, Vincent François, and Karl E. Kadler: Deletion of Epidermal Growth Factor-like Domains Converts Mammalian Tolloid into a Chordinase and Effective Procollagen C-proteinase
J. Biol. Chem. 2004 279: 49835-49841. First Published on September 20, 2004; doi:10.1074/jbc.M408134200 [Abstract] [Full Text] [PDF]

Yeongjin Hong, Subha Sundaram, Dong-Jun Shin, and Pamela Stanley: The Lec23 Chinese Hamster Ovary Mutant Is a Sensitive Host for Detecting Mutations in ${alpha}$ -Glucosidase I That Give Rise to Congenital Disorder of Glycosylation IIb (CDG IIb)
J. Biol. Chem. 2004 279: 49894-49901. First Published on September 21, 2004; doi:10.1074/jbc.M410121200 [Abstract] [Full Text] [PDF]

Yunxiang Zhu, Xuemei Li, Josephine Kyazike, Qun Zhou, Beth L. Thurberg, Nina Raben, Robert J. Mattaliano, and Seng H. Cheng: Conjugation of Mannose 6-Phosphate-containing Oligosaccharides to Acid ${alpha}$ -Glucosidase Improves the Clearance of Glycogen in Pompe Mice
J. Biol. Chem. 2004 279: 50336-50341. First Published on September 21, 2004; doi:10.1074/jbc.M409676200 [Abstract] [Full Text] [PDF]

E Tian, Kelly G. Ten Hagen, Lillian Shum, Howard C. Hang, Yoannis Imbert, William W. Young, Jr, Carolyn R. Bertozzi, and Lawrence A. Tabak: An Inhibitor of O-Glycosylation Induces Apoptosis in NIH3T3 Cells and Developing Mouse Embryonic Mandibular Tissues
J. Biol. Chem. 2004 279: 50382-50390. First Published on September 1, 2004; doi:10.1074/jbc.M406397200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Charulatha Vedhachalam, Lijuan Liu, Margaret Nickel, Padmaja Dhanasekaran, G. M. Anantharamaiah, Sissel Lund-Katz, George H. Rothblat, and Michael C. Phillips: Influence of ApoA-I Structure on the ABCA1-mediated Efflux of Cellular Lipids
J. Biol. Chem. 2004 279: 49931-49939. First Published on September 21, 2004; doi:10.1074/jbc.M406924200 [Abstract] [Full Text] [PDF]

Peng Li, Thorsten Wohland, Bow Ho, and Jeak Ling Ding: Perturbation of Lipopolysaccharide (LPS) Micelles by Sushi 3 (S3) Antimicrobial Peptide: THE IMPORTANCE OF AN INTERMOLECULAR DISULFIDE BOND IN S3 DIMER FOR BINDING, DISRUPTION, AND NEUTRALIZATION OF LPS
J. Biol. Chem. 2004 279: 50150-50156. First Published on August 24, 2004; doi:10.1074/jbc.M405606200 [Abstract] [Full Text] [PDF]

Hisashi Hemmi, Kyohei Shibuya, Yoshihiro Takahashi, Toru Nakayama, and Tokuzo Nishino: (S)-2,3-Di-O-geranylgeranylglyceryl Phosphate Synthase from the Thermoacidophilic Archaeon Sulfolobus solfataricus: MOLECULAR CLONING AND CHARACTERIZATION OF A MEMBRANE-INTRINSIC PRENYLTRANSFERASE INVOLVED IN THE BIOSYNTHESIS OF ARCHAEAL ETHER-LINKED MEMBRANE LIPIDS
J. Biol. Chem. 2004 279: 50197-50203. First Published on September 8, 2004; doi:10.1074/jbc.M409207200 [Abstract] [Full Text] [PDF]

Sahng Wook Park, Young-Ah Moon, and Jay D. Horton: Post-transcriptional Regulation of Low Density Lipoprotein Receptor Protein by Proprotein Convertase Subtilisin/Kexin Type 9a in Mouse Liver
J. Biol. Chem. 2004 279: 50630-50638. First Published on September 22, 2004; doi:10.1074/jbc.M410077200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Anne-Kristine Meinild, Harald H. Sitte, and Ulrik Gether: Zinc Potentiates an Uncoupled Anion Conductance Associated with the Dopamine Transporter
J. Biol. Chem. 2004 279: 49671-49679. First Published on September 9, 2004; doi:10.1074/jbc.M407660200 [Abstract] [Full Text] [PDF]

Jaehoon Jung, Moonhee Kim, Min-Jeong Kim, Jinyoung Kim, Jiae Moon, Jae-Su Lim, Miyoung Kim, and Kyunglim Lee: Translationally Controlled Tumor Protein Interacts with the Third Cytoplasmic Domain of Na,K-ATPase ${alpha}$ Subunit and Inhibits the Pump Activity in HeLa Cells
J. Biol. Chem. 2004 279: 49868-49875. First Published on September 21, 2004; doi:10.1074/jbc.M400895200 [Abstract] [Full Text] [PDF]

Man Liu and Andreas Barth: Phosphorylation of the Sarcoplasmic Reticulum Ca²+-ATPase from ATP and ATP Analogs Studied by Infrared Spectroscopy
J. Biol. Chem. 2004 279: 49902-49909. First Published on September 20, 2004; doi:10.1074/jbc.M408062200 [Abstract] [Full Text] [PDF]

Karen Engel, Mingyan Zhou, and Joanne Wang: Identification and Characterization of a Novel Monoamine Transporter in the Human Brain
J. Biol. Chem. 2004 279: 50042-50049. First Published on September 23, 2004; doi:10.1074/jbc.M407913200 [Abstract] [Full Text] [PDF]

Lena Burri, Katherine Vascotto, Steffen Fredersdorf, Ralph Tiedt, Michael N. Hall, and Trevor Lithgow: Zim17, a Novel Zinc Finger Protein Essential for Protein Import into Mitochondria
J. Biol. Chem. 2004 279: 50243-50249. First Published on September 21, 2004; doi:10.1074/jbc.M409194200 [Abstract] [Full Text] [PDF]

Su Yu, Sara A. Michie, and Anson W. Lowe: Absence of the Major Zymogen Granule Membrane Protein, GP2, Does Not Affect Pancreatic Morphology or Secretion
J. Biol. Chem. 2004 279: 50274-50279. First Published on September 22, 2004; doi:10.1074/jbc.M410599200 [Abstract] [Full Text] [PDF]

Kelly R. Pitts, Mark A. McNiven, and Yisang Yoon: Mitochondria-specific Function of the Dynamin Family Protein DLP1 Is Mediated by Its C-terminal Domains
J. Biol. Chem. 2004 279: 50286-50294. First Published on September 13, 2004; doi:10.1074/jbc.M405531200 [Abstract] [Full Text] [PDF]

Gloria Riquelme, Paola Llanos, Erin Tischner, Jessica Neil, and Begoña Campos: Annexin 6 Modulates the Maxi-chloride Channel of the Apical Membrane of Syncytiotrophoblast Isolated from Human Placenta
J. Biol. Chem. 2004 279: 50601-50608. First Published on September 7, 2004; doi:10.1074/jbc.M407859200 [Abstract] [Full Text] [PDF]

Hiroyuki Suzuki, Tomoko Kadowaki, Maki Maeda, Hiroyuki Sasaki, Junichi Nabekura, Masao Sakaguchi, and Katsuyoshi Mihara: Membrane-embedded C-terminal Segment of Rat Mitochondrial TOM40 Constitutes Protein-conducting Pore with Enriched ${beta}$ -Structure
J. Biol. Chem. 2004 279: 50619-50629. First Published on September 3, 2004; doi:10.1074/jbc.M408604200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Kiyoshi Yamaguchi, Seong-Ho Lee, Thomas E. Eling, and Seung Joon Baek: Identification of Nonsteroidal Anti-inflammatory Drug-activated Gene (NAG-1) as a Novel Downstream Target of Phosphatidylinositol 3-Kinase/AKT/GSK-3 ${beta}$ Pathway
J. Biol. Chem. 2004 279: 49617-49623. First Published on September 17, 2004; doi:10.1074/jbc.M408796200 [Abstract] [Full Text] [PDF]

Danielle Mesnier and Jean-Louis Banères: Cooperative Conformational Changes in a G-protein-coupled Receptor Dimer, the Leukotriene B₄ Receptor BLT1
J. Biol. Chem. 2004 279: 49664-49670. First Published on September 9, 2004; doi:10.1074/jbc.M404941200 [Abstract] [Full Text] [PDF]

Feng Gu, Duc Thang Nguyên, Matthew Stuible, Nadia Dubé, Michel L. Tremblay, and Eric Chevet: Protein-tyrosine Phosphatase 1B Potentiates IRE1 Signaling during Endoplasmic Reticulum Stress
J. Biol. Chem. 2004 279: 49689-49693. First Published on October 1, 2004; doi:10.1074/jbc.C400261200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Xiaoqing Gan, Zhihai Ma, Ning Deng, Jiyong Wang, Jianping Ding, and Lin Li: Involvement of the C-terminal Proline-rich Motif of G Protein-coupled Receptor Kinases in Recognition of Activated Rhodopsin
J. Biol. Chem. 2004 279: 49741-49746. First Published on September 16, 2004; doi:10.1074/jbc.M407570200 [Abstract] [Full Text] [PDF]

Nawal M. Al-Rasheed, Ravinder S. Chana, Richard J. Baines, Gary B. Willars, and Nigel J. Brunskill: Ligand-independent Activation of Peroxisome Proliferator-activated Receptor- ${gamma}$ by Insulin and C-peptide in Kidney Proximal Tubular Cells: DEPENDENT ON PHOSPHATIDYLINOSITOL 3-KINASE ACTIVITY
J. Biol. Chem. 2004 279: 49747-49754. First Published on September 16, 2004; doi:10.1074/jbc.M408268200 [Abstract] [Full Text] [PDF]

Daisuke Inoue, Shinsuke Kido, and Toshio Matsumoto: Transcriptional Induction of FosB/ ${Delta}$ FosB Gene by Mechanical Stress in Osteoblasts
J. Biol. Chem. 2004 279: 49795-49803. First Published on September 20, 2004; doi:10.1074/jbc.M404096200 [Abstract] [Full Text] [PDF]

Dan Gratschev, Tomas Blom, Sonja Björklund, and Kid Törnquist: Phosphatase Inhibition Reveals a Calcium Entry Pathway Dependent on Protein Kinase A in Thyroid FRTL-5 Cells: COMPARISON WITH STORE-OPERATED CALCIUM ENTRY
J. Biol. Chem. 2004 279: 49816-49824. First Published on September 20, 2004; doi:10.1074/jbc.M406364200 [Abstract] [Full Text] [PDF]

Charles S. Hii, Donald S. Anson, Maurizio Costabile, Violet Mukaro, Kylie Dunning, and Antonio Ferrante: Characterization of the MEK5-ERK5 Module in Human Neutrophils and Its Relationship to ERK1/ERK2 in the Chemotactic Response
J. Biol. Chem. 2004 279: 49825-49834. First Published on September 20, 2004; doi:10.1074/jbc.M406892200 [Abstract] [Full Text] [PDF]

Alexander Staruschenko, Amy Nichols, Jorge L. Medina, Patricia Camacho, Nadezhda N. Zheleznova, and James D. Stockand: Rho Small GTPases Activate the Epithelial Na⁺ Channel
J. Biol. Chem. 2004 279: 49989-49994. First Published on September 23, 2004; doi:10.1074/jbc.M409812200 [Abstract] [Full Text] [PDF]

Magdalena Koziczak and Nancy E. Hynes: Cooperation between Fibroblast Growth Factor Receptor-4 and ErbB2 in Regulation of Cyclin D1 Translation
J. Biol. Chem. 2004 279: 50004-50011. First Published on September 17, 2004; doi:10.1074/jbc.M404252200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Helen Garside, Adam Stevens, Stuart Farrow, Claire Normand, Benoit Houle, Andy Berry, Barbara Maschera, and David Ray: Glucocorticoid Ligands Specify Different Interactions with NF- ${kappa}$ B by Allosteric Effects on the Glucocorticoid Receptor DNA Binding Domain
J. Biol. Chem. 2004 279: 50050-50059. First Published on September 8, 2004; doi:10.1074/jbc.M407309200 [Abstract] [Full Text] [PDF]

Shi Jie Liu, Jia Yu Zhang, Hong Lian Li, Zheng Yu Fang, Qun Wang, Heng Mei Deng, Cheng Xin Gong, Inge Grundke-Iqbal, Khalid Iqbal, and Jian Zhi Wang: Tau Becomes a More Favorable Substrate for GSK-3 When It Is Prephosphorylated by PKA in Rat Brain
J. Biol. Chem. 2004 279: 50078-50088. First Published on September 15, 2004; doi:10.1074/jbc.M406109200 [Abstract] [Full Text] [PDF]

Chris M. Jacobs, Karen A. Boldingh, Hege H. Slagsvold, G. Hege Thoresen, and Ragnhild E. Paulsen: ERK2 Prohibits Apoptosis-induced Subcellular Translocation of Orphan Nuclear Receptor NGFI-B/TR3
J. Biol. Chem. 2004 279: 50097-50101. First Published on September 23, 2004; doi:10.1074/jbc.M409145200 [Abstract] [Full Text] [PDF]

Shuichi Kani, Isao Oishi, Hiroyuki Yamamoto, Akinori Yoda, Hiroaki Suzuki, Akira Nomachi, Kengo Iozumi, Michiru Nishita, Akira Kikuchi, Toru Takumi, and Yasuhiro Minami: The Receptor Tyrosine Kinase Ror2 Associates with and Is Activated by Casein Kinase I ${epsilon}$
J. Biol. Chem. 2004 279: 50102-50109. First Published on September 15, 2004; doi:10.1074/jbc.M409039200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Xin Ye, Grzegorz Nalepa, Markus Welcker, Benedikt M. Kessler, Eric Spooner, Jun Qin, Stephen J. Elledge, Bruce E. Clurman, and J. Wade Harper: Recognition of Phosphodegron Motifs in Human Cyclin E by the SCF^Fbw7 Ubiquitin Ligase
J. Biol. Chem. 2004 279: 50110-50119. First Published on September 13, 2004; doi:10.1074/jbc.M409226200 [Abstract] [Full Text] [PDF]

Yoichi Mizukami, Akihiro Iwamatsu, Toshihiko Aki, Masayasu Kimura, Kazuyuki Nakamura, Tomoko Nao, Tomoko Okusa, Masunori Matsuzaki, Ken-ichi Yoshida, and Sei Kobayashi: ERK1/2 Regulates Intracellular ATP Levels through ${alpha}$ -Enolase Expression in Cardiomyocytes Exposed to Ischemic Hypoxia and Reoxygenation
J. Biol. Chem. 2004 279: 50120-50131. First Published on September 30, 2004; doi:10.1074/jbc.M402299200 [Abstract] [Full Text] [PDF]

Yvonne L. Woods, Dimitris P. Xirodimas, Alan R. Prescott, Alison Sparks, David P. Lane, and Mark K. Saville: p14 Arf Promotes Small Ubiquitin-like Modifier Conjugation of Werners Helicase
J. Biol. Chem. 2004 279: 50157-50166. First Published on September 7, 2004; doi:10.1074/jbc.M405414200 [Abstract] [Full Text] [PDF]

Adam R. Cole, Axel Knebel, Nick A. Morrice, Laura A. Robertson, Andrew J. Irving, Chris N. Connolly, and Calum Sutherland: GSK-3 Phosphorylation of the Alzheimer Epitope within Collapsin Response Mediator Proteins Regulates Axon Elongation in Primary Neurons
J. Biol. Chem. 2004 279: 50176-50180. First Published on October 5, 2004; doi:10.1074/jbc.C400412200 [Abstract] [Full Text] [PDF]

Tianyun Jiang, Zhiyong Guo, Bojie Dai, Miyoung Kang, David K. Ann, Hsing-Jien Kung, and Yun Qiu: Bi-directional Regulation between Tyrosine Kinase Etk/BMX and Tumor Suppressor p53 in Response to DNA Damage
J. Biol. Chem. 2004 279: 50181-50189. First Published on September 8, 2004; doi:10.1074/jbc.M409108200 [Abstract] [Full Text] [PDF]

Junqi He, Michele Bellini, Jianguo Xu, Amanda M. Castleberry, and Randy A. Hall: Interaction with Cystic Fibrosis Transmembrane Conductance Regulator-associated Ligand (CAL) Inhibits ${beta}$ 1-Adrenergic Receptor Surface Expression
J. Biol. Chem. 2004 279: 50190-50196. First Published on September 9, 2004; doi:10.1074/jbc.M404876200 [Abstract] [Full Text] [PDF]

Lucia Cilenti, Mangala M. Soundarapandian, George A. Kyriazis, Valerie Stratico, Supriya Singh, Sanjeev Gupta, Joseph V. Bonventre, Emad S. Alnemri, and Antonis S. Zervos: Regulation of HAX-1 Anti-apoptotic Protein by Omi/HtrA2 Protease during Cell Death
J. Biol. Chem. 2004 279: 50295-50301. First Published on September 15, 2004; doi:10.1074/jbc.M406006200 [Abstract] [Full Text] [PDF]

Uta Keil, Astrid Bonert, Celio A. Marques, Isabel Scherping, Jörg Weyermann, Joanna B. Strosznajder, Franz Müller-Spahn, Christian Haass, Christian Czech, Laurent Pradier, Walter E. Müller, and Anne Eckert: Amyloid ${beta}$ -induced Changes in Nitric Oxide Production and Mitochondrial Activity Lead to Apoptosis
J. Biol. Chem. 2004 279: 50310-50320. First Published on September 14, 2004; doi:10.1074/jbc.M405600200 [Abstract] [Full Text] [PDF]

Igor V. Peshenko, Elena V. Olshevskaya, and Alexander M. Dizhoor: Ca²⁺-dependent Conformational Changes in Guanylyl Cyclase-activating Protein 2 (GCAP-2) Revealed by Site-specific Phosphorylation and Partial Proteolysis
J. Biol. Chem. 2004 279: 50342-50349. First Published on September 23, 2004; doi:10.1074/jbc.M408683200 [Abstract] [Full Text] [PDF]

Dieter Wicher, Sandra Messutat, Céline Lavialle, and Bruno Lapied: A New Regulation of Non-capacitative Calcium Entry in Insect Pacemaker Neurosecretory Neurons: INVOLVEMENT OF ARACHIDONIC ACID, NO-GUANYLYL CYCLASE/cGMP, AND cAMP
J. Biol. Chem. 2004 279: 50410-50419. First Published on September 13, 2004; doi:10.1074/jbc.M405800200 [Abstract] [Full Text] [PDF]

Jianqiang Yu, Dafang Bian, Chitladda Mahanivong, Robert K. Cheng, Wenyun Zhou, and Shuang Huang: p38 Mitogen-activated Protein Kinase Regulation of Endothelial Cell Migration Depends on Urokinase Plasminogen Activator Expression
J. Biol. Chem. 2004 279: 50446-50454. First Published on September 14, 2004; doi:10.1074/jbc.M409221200 [Abstract] [Full Text] [PDF]

Suparna Qanungo, Mi Wang, and Anna-Liisa Nieminen: N-Acetyl-L-cysteine Enhances Apoptosis through Inhibition of Nuclear Factor- ${kappa}$ B in Hypoxic Murine Embryonic Fibroblasts
J. Biol. Chem. 2004 279: 50455-50464. First Published on September 16, 2004; doi:10.1074/jbc.M406749200 [Abstract] [Full Text] [PDF]

Olivier Sordet, Qasim A. Khan, Isabelle Plo, Philippe Pourquier, Yoshimasa Urasaki, Akira Yoshida, Smitha Antony, Glenda Kohlhagen, Eric Solary, Murat Saparbaev, Jacques Laval, and Yves Pommier: Apoptotic Topoisomerase I-DNA Complexes Induced by Staurosporine-mediated Oxygen Radicals
J. Biol. Chem. 2004 279: 50499-50504. First Published on September 22, 2004; doi:10.1074/jbc.M410277200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Molecular Basis Of Cell and Developmental Biology:

Annette R. Atkins, Warren J. Gallin, Geoffrey C. Owens, Gerald M. Edelman, and Bruce A. Cunningham: Neural Cell Adhesion Molecule (N-CAM) Homophilic Binding Mediated by the Two N-terminal Ig Domains Is Influenced by Intramolecular Domain-Domain Interactions
J. Biol. Chem. 2004 279: 49633-49643. First Published on September 20, 2004; doi:10.1074/jbc.M409159200 [Abstract] [Full Text] [PDF]

Shun-ichi Kurata, Takeshi Okuyama, Motonobu Osada, Tatsuya Watanabe, Yoshiya Tomimori, Shingo Sato, Aki Iwai, Tsutomu Tsuji, Yoji Ikawa, and Iyoko Katoh: p51/p63 Controls Subunit ${alpha}$ ₃ of the Major Epidermis Integrin Anchoring the Stem Cells to the Niche
J. Biol. Chem. 2004 279: 50069-50077. First Published on September 12, 2004; doi:10.1074/jbc.M406322200 [Abstract] [Full Text] [PDF]

John W. Copeland, Sarah J. Copeland, and Richard Treisman: Homo-oligomerization Is Essential for F-actin Assembly by the Formin Family FH2 Domain
J. Biol. Chem. 2004 279: 50250-50256. First Published on September 14, 2004; doi:10.1074/jbc.M404429200 [Abstract] [Full Text] [PDF]

Dmitri V. Rozanov, Sergey Sikora, Adam Godzik, Tatiana I. Postnova, Vladislav Golubkov, Alexei Savinov, Stephen Tomlinson, and Alex Y. Strongin: Non-proteolytic, Receptor/Ligand Interactions Associate Cellular Membrane Type-1 Matrix Metalloproteinase with the Complement Component C1q
J. Biol. Chem. 2004 279: 50321-50328. First Published on September 16, 2004; doi:10.1074/jbc.M409174200 [Abstract] [Full Text] [PDF]

Steffen W. Schubert, Elena Kardash, Muhammad Amir Khan, Tatiana Cheusova, Karin Kilian, Michael Wegner, and Said Hashemolhosseini: Interaction, Cooperative Promoter Modulation, and Renal Colocalization of GCMa and Pitx2
J. Biol. Chem. 2004 279: 50358-50365. First Published on September 22, 2004; doi:10.1074/jbc.M404587200 [Abstract] [Full Text] [PDF]

Nobuhiro Morishima, Keiko Nakanishi, Kyoko Tsuchiya, Takehiko Shibata, and Emiko Seiwa: Translocation of Bim to the Endoplasmic Reticulum (ER) Mediates ER Stress Signaling for Activation of Caspase-12 during ER Stress-induced Apoptosis
J. Biol. Chem. 2004 279: 50375-50381. First Published on September 27, 2004; doi:10.1074/jbc.M408493200 [Abstract] [Full Text] [PDF]

Mimi Tamamori-Adachi, Kentaro Hayashida, Kiyoshi Nobori, Chie Omizu, Kazuhiko Yamada, Naoya Sakamoto, Takumi Kamura, Keiichi Fukuda, Satoshi Ogawa, Keiichi I. Nakayama, and Shigetaka Kitajima: Down-regulation of p27^Kip1 Promotes Cell Proliferation of Rat Neonatal Cardiomyocytes Induced by Nuclear Expression of Cyclin D1 and CDK4: EVIDENCE FOR IMPAIRED Skp2-DEPENDENT DEGRADATION OF p27 IN TERMINAL DIFFERENTIATION
J. Biol. Chem. 2004 279: 50429-50436. First Published on September 13, 2004; doi:10.1074/jbc.M403084200 [Abstract] [Full Text] [PDF]

Kelley M. Argraves, Brent A. Wilkerson, W. Scott Argraves, Paul A. Fleming, Lina M. Obeid, and Christopher J. Drake: Sphingosine-1-phosphate Signaling Promotes Critical Migratory Events in Vasculogenesis
J. Biol. Chem. 2004 279: 50580-50590. First Published on September 17, 2004; doi:10.1074/jbc.M404432200 [Abstract] [Full Text] [PDF]