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Table of Contents: Dec 31 2004; 279 (53)   [Index by Author]  [Papers Of The Week] [Cover Figure and Caption]
       Papers Of The Week
       Reflections
       Classics
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Papers Of The Week:


Nuclear Localization Destabilizes the Stress-regulated Transcription Factor Msn2

J. Biol. Chem. 2004 279: e99933. [Full Text] [PDF]  


Hsp70 and Hsp40 Chaperones Do Not Modulate Retinal Phenotype in SCA7 Mice

J. Biol. Chem. 2004 279: e99934. [Full Text] [PDF]  


Reflections:

Clinton E. Ballou
My Brief Encounter with the Phosphoinositides and IP3
J. Biol. Chem. 2004 279: 54975-54982. First Published on October 8, 2004; doi:10.1074/jbc.X400010200 [Full Text] [PDF]  


Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill
Succeeding in Science Despite the Odds; Studying Metabolism with NMR by Mildred Cohn
A STUDY OF OXIDATIVE PHOSPHORYLATION WITH O18-LABELED INORGANIC PHOSPHATE (Mildred Cohn J. Biol. Chem. 201, 735-750)
Nuclear Magnetic Resonance Spectra of Adenosine Di- and Triphosphate. II. EFFECT OF COMPLEXING WITH DIVALENT METAL IONS (Mildred Cohn and Thomas R. Hughes, Jr. J. Biol. Chem. 237, 176-181)
J. Biol. Chem. 2004 279: e12. [Full Text]  


Accelerated Publications:

Deguang Zhu, Kenneth S. Kosik, Thomas E. Meigs, Vijay Yanamadala, and Bradley M. Denker
G{alpha}12 Directly Interacts with PP2A: EVIDENCE FOR G{alpha}12-STIMULATED PP2A PHOSPHATASE ACTIVITY AND DEPHOSPHORYLATION OF MICROTUBULE-ASSOCIATED PROTEIN, Tau
J. Biol. Chem. 2004 279: 54983-54986. First Published on November 3, 2004; doi:10.1074/jbc.C400508200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:

Shelley L. Lusetti, Julia C. Drees, Elizabeth A. Stohl, H. Steven Seifert, and Michael M. Cox
The DinI and RecX Proteins Are Competing Modulators of RecA Function
J. Biol. Chem. 2004 279: 55073-55079. First Published on October 15, 2004; doi:10.1074/jbc.M410371200 [Abstract] [Full Text] [PDF]  

Marc Audebert, Bernard Salles, and Patrick Calsou
Involvement of Poly(ADP-ribose) Polymerase-1 and XRCC1/DNA Ligase III in an Alternative Route for DNA Double-strand Breaks Rejoining
J. Biol. Chem. 2004 279: 55117-55126. First Published on October 21, 2004; doi:10.1074/jbc.M404524200 [Abstract] [Full Text] [PDF]  

David S. Levin, Sangeetha Vijayakumar, Xiuping Liu, Vladimir P. Bermudez, Jerard Hurwitz, and Alan E. Tomkinson
A Conserved Interaction between the Replicative Clamp Loader and DNA Ligase in Eukaryotes: IMPLICATIONS FOR OKAZAKI FRAGMENT JOINING
J. Biol. Chem. 2004 279: 55196-55201. First Published on October 23, 2004; doi:10.1074/jbc.M409250200 [Abstract] [Full Text] [PDF]  

Edwin Kamau, Kevin T. Bauerle, and Anne Grove
The Saccharomyces cerevisiae High Mobility Group Box Protein HMO1 Contains Two Functional DNA Binding Domains
J. Biol. Chem. 2004 279: 55234-55240. First Published on October 25, 2004; doi:10.1074/jbc.M409459200 [Abstract] [Full Text] [PDF]  

Sairei So, Noritaka Adachi, Michael R. Lieber, and Hideki Koyama
Genetic Interactions between BLM and DNA Ligase IV in Human Cells
J. Biol. Chem. 2004 279: 55433-55442. First Published on October 26, 2004; doi:10.1074/jbc.M409827200 [Abstract] [Full Text] [PDF]  

Ashwini S. Kamath-Loeb, Piri Welcsh, Maureen Waite, Elinor T. Adman, and Lawrence A. Loeb
The Enzymatic Activities of the Werner Syndrome Protein Are Disabled by the Amino Acid Polymorphism R834C
J. Biol. Chem. 2004 279: 55499-55505. First Published on October 15, 2004; doi:10.1074/jbc.M407128200 [Abstract] [Full Text] [PDF]  

Paul A. Jowsey, Aidan J. Doherty, and John Rouse
Human PTIP Facilitates ATM-mediated Activation of p53 and Promotes Cellular Resistance to Ionizing Radiation
J. Biol. Chem. 2004 279: 55562-55569. First Published on September 27, 2004; doi:10.1074/jbc.M411021200 [Abstract] [Full Text] [PDF]  

Hans U. Barthelmes, Michael Habermeyer, Morten O. Christensen, Christian Mielke, Heidrun Interthal, Jeffrey J. Pouliot, Fritz Boege, and Doris Marko
TDP1 Overexpression in Human Cells Counteracts DNA Damage Mediated by Topoisomerases I and II
J. Biol. Chem. 2004 279: 55618-55625. First Published on October 19, 2004; doi:10.1074/jbc.M405042200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Andy C. Lin, Andrea E. Roche, Jeannine Wilk, and Eric C. Svensson
The N Termini of Friend of GATA (FOG) Proteins Define a Novel Transcriptional Repression Motif and a Superfamily of Transcriptional Repressors
J. Biol. Chem. 2004 279: 55017-55023. First Published on October 25, 2004; doi:10.1074/jbc.M411240200 [Abstract] [Full Text] [PDF]  

Ellice Y. Wong, Jolinta Lin, Bernard G. Forget, David M. Bodine, and Patrick G. Gallagher
Sequences Downstream of the Erythroid Promoter Are Required for High Level Expression of the Human {alpha}-Spectrin Gene
J. Biol. Chem. 2004 279: 55024-55033. First Published on September 27, 2004; doi:10.1074/jbc.M408886200 [Abstract] [Full Text] [PDF]  

Wei Tan, Seokjoong Kim, and Thomas G. Boyer
Tetrameric Oligomerization Mediates Transcriptional Repression by the BRCA1-dependent Kruppel-associated Box-Zinc Finger Protein ZBRK1
J. Biol. Chem. 2004 279: 55153-55160. First Published on October 20, 2004; doi:10.1074/jbc.M410926200 [Abstract] [Full Text] [PDF]  

Stephan Lacour, Olivier Leroy, Annie Kolb, and Paolo Landini
Substitutions in Region 2.4 of {sigma}70 Allow Recognition of the {sigma}S-Dependent aidB Promoter
J. Biol. Chem. 2004 279: 55255-55261. First Published on October 26, 2004; doi:10.1074/jbc.M410855200 [Abstract] [Full Text] [PDF]  

Urs Schneider, Kareen Blechschmidt, Martin Schwemmle, and Peter Staeheli
Overlap of Interaction Domains Indicates a Central Role of the P Protein in Assembly and Regulation of the Borna Disease Virus Polymerase Complex
J. Biol. Chem. 2004 279: 55290-55296. First Published on October 27, 2004; doi:10.1074/jbc.M408913200 [Abstract] [Full Text] [PDF]  

Koji Ikeda and Thomas Quertermous
Molecular Isolation and Characterization of a Soluble Isoform of Activated Leukocyte Cell Adhesion Molecule That Modulates Endothelial Cell Function
J. Biol. Chem. 2004 279: 55315-55323. First Published on October 20, 2004; doi:10.1074/jbc.M407776200 [Abstract] [Full Text] [PDF]  

Jun Lu, Wen Zhao, and Laura S. Frost
Mutational Analysis of TraM Correlates Oligomerization and DNA Binding with Autoregulation and Conjugative DNA Transfer
J. Biol. Chem. 2004 279: 55324-55333. First Published on October 26, 2004; doi:10.1074/jbc.M409352200 [Abstract] [Full Text] [PDF]  

Takumi Nishiuchi, Hideaki Shinshi, and Kaoru Suzuki
Rapid and Transient Activation of Transcription of the ERF3 Gene by Wounding in Tobacco Leaves: POSSIBLE INVOLVEMENT OF NtWRKYs AND AUTOREPRESSION
J. Biol. Chem. 2004 279: 55355-55361. First Published on October 27, 2004; doi:10.1074/jbc.M409674200 [Abstract] [Full Text] [PDF]  

Shuwen Wang and Jiyue Zhu
The hTERT Gene Is Embedded in a Nuclease-resistant Chromatin Domain
J. Biol. Chem. 2004 279: 55401-55410. First Published on October 29, 2004; doi:10.1074/jbc.M411352200 [Abstract] [Full Text] [PDF]  

Sélène Ferrari, Katia Carmine Simmen, Yves Dusserre, Karin Müller, Geneviève Fourel, Eric Gilson, and Nicolas Mermod
Chromatin Domain Boundaries Delimited by a Histone-binding Protein in Yeast
J. Biol. Chem. 2004 279: 55520-55530. First Published on October 7, 2004; doi:10.1074/jbc.M410346200 [Abstract] [Full Text] [PDF] Supplemental Data  

Xiaomin Zhang, Gohar Azhar, Ying Zhong, and Jeanne Y. Wei
Identification of a Novel Serum Response Factor Cofactor in Cardiac Gene Regulation
J. Biol. Chem. 2004 279: 55626-55632. First Published on October 18, 2004; doi:10.1074/jbc.M405945200 [Abstract] [Full Text] [PDF]  

Marguerite Lemonnier and Margaret E. Buckingham
Characterization of a Cardiac-specific Enhancer, Which Directs {alpha}-Cardiac Actin Gene Transcription in the Mouse Adult Heart
J. Biol. Chem. 2004 279: 55651-55658. First Published on October 18, 2004; doi:10.1074/jbc.M411082200 [Abstract] [Full Text] [PDF]  

Louise J. Lloyd, Susan E. Jones, Goran Jovanovic, Prasad Gyaneshwar, Matthew D. Rolfe, Arthur Thompson, Jay C. Hinton, and Martin Buck
Identification of a New Member of the Phage Shock Protein Response in Escherichia coli, the Phage Shock Protein G (PspG)
J. Biol. Chem. 2004 279: 55707-55714. First Published on October 13, 2004; doi:10.1074/jbc.M408994200 [Abstract] [Full Text] [PDF] Supplemental Data  

Jeffrey W. Streb, Chad M. Kitchen, Irwin H. Gelman, and Joseph M. Miano
Multiple Promoters Direct Expression of Three AKAP12 Isoforms with Distinct Subcellular and Tissue Distribution Profiles
J. Biol. Chem. 2004 279: 56014-56023. First Published on October 20, 2004; doi:10.1074/jbc.M408828200 [Abstract] [Full Text] [PDF]  

Shizuko Tanaka, Taras T. Antoniv, Ke Liu, Lu Wang, Dominic J. Wells, Francesco Ramirez, and George Bou-Gharios
Cooperativity between Far Upstream Enhancer and Proximal Promoter Elements of the Human {alpha}2(I) Collagen (COL1A2) Gene Instructs Tissue Specificity in Transgenic Mice
J. Biol. Chem. 2004 279: 56024-56031. First Published on October 29, 2004; doi:10.1074/jbc.M411406200 [Abstract] [Full Text] [PDF]  

Maria V. Panchenko, Mina I. Zhou, and Herbert T. Cohen
von Hippel-Lindau Partner Jade-1 Is a Transcriptional Co-activator Associated with Histone Acetyltransferase Activity
J. Biol. Chem. 2004 279: 56032-56041. First Published on October 22, 2004; doi:10.1074/jbc.M410487200 [Abstract] [Full Text] [PDF]  

Myung-Chul Chung and Sachiyo Kawamoto
IRF-2 Is Involved in Up-regulation of Nonmuscle Myosin Heavy Chain II-A Gene Expression during Phorbol Ester-induced Promyelocytic HL-60 Differentiation
J. Biol. Chem. 2004 279: 56042-56052. First Published on October 20, 2004; doi:10.1074/jbc.M404791200 [Abstract] [Full Text] [PDF]  


RNA: Structure, Metabolism, and Catalysis:

Kyriaki Galani, T. Amar Nissan, Elisabeth Petfalski, David Tollervey, and Ed Hurt
Rea1, a Dynein-related Nuclear AAA-ATPase, Is Involved in Late rRNA Processing and Nuclear Export of 60 S Subunits
J. Biol. Chem. 2004 279: 55411-55418. First Published on November 3, 2004; doi:10.1074/jbc.M406876200 [Abstract] [Full Text] [PDF] Supplemental Data  


Protein Synthesis, Post-Translation Modification, and Degradation:

Nariyasu Mano, Kie Kasuga, Norihiro Kobayashi, and Junichi Goto
A Nonenzymatic Modification of the Amino-terminal Domain of Histone H3 by Bile Acid Acyl Adenylate
J. Biol. Chem. 2004 279: 55034-55041. First Published on October 1, 2004; doi:10.1074/jbc.M409205200 [Abstract] [Full Text] [PDF]  

Li Wang, Xicheng Mao, Donghong Ju, and Youming Xie
Rpn4 Is a Physiological Substrate of the Ubr2 Ubiquitin Ligase
J. Biol. Chem. 2004 279: 55218-55223. First Published on October 25, 2004; doi:10.1074/jbc.M410085200 [Abstract] [Full Text] [PDF]  

Catherine E. Jessop and Neil J. Bulleid
Glutathione Directly Reduces an Oxidoreductase in the Endoplasmic Reticulum of Mammalian Cells
J. Biol. Chem. 2004 279: 55341-55347. First Published on October 26, 2004; doi:10.1074/jbc.M411409200 [Abstract] [Full Text] [PDF]  

Bettina Drisaldi, Janaky Coomaraswamy, Peter Mastrangelo, Bob Strome, Jing Yang, Joel C. Watts, M. Azhar Chishti, Melissa Marvi, Otto Windl, Rosemary Ahrens, François Major, Man-Sun Sy, Hans Kretzschmar, Paul E. Fraser, Howard T. J. Mount, and David Westaway
Genetic Mapping of Activity Determinants within Cellular Prion Proteins: N-TERMINAL MODULES IN PrPC OFFSET PRO-APOPTOTIC ACTIVITY OF THE DOPPEL HELIX B/B' REGION
J. Biol. Chem. 2004 279: 55443-55454. First Published on September 29, 2004; doi:10.1074/jbc.M404794200 [Abstract] [Full Text] [PDF]  

Manuel Llano, Sharon Delgado, Maria Vanegas, and Eric M. Poeschla
Lens Epithelium-derived Growth Factor/p75 Prevents Proteasomal Degradation of HIV-1 Integrase
J. Biol. Chem. 2004 279: 55570-55577. First Published on October 8, 2004; doi:10.1074/jbc.M408508200 [Abstract] [Full Text] [PDF]  

Inmaculada Navarro-Lérida, Maria Martha Corvi, Alberto Álvarez Barrientos, Francisco Gavilanes, Luc Gérard Berthiaume, and Ignacio Rodríguez-Crespo
Palmitoylation of Inducible Nitric-oxide Synthase at Cys-3 Is Required for Proper Intracellular Traffic and Nitric Oxide Synthesis
J. Biol. Chem. 2004 279: 55682-55689. First Published on October 13, 2004; doi:10.1074/jbc.M406621200 [Abstract] [Full Text] [PDF]  

Laura Morelli, Ramiro E. Llovera, Irina Mathov, Lih-Fen Lue, Blas Frangione, Jorge Ghiso, and Eduardo M. Castaño
Insulin-degrading Enzyme in Brain Microvessels: PROTEOLYSIS OF AMYLOID {beta} VASCULOTROPIC VARIANTS AND REDUCED ACTIVITY IN CEREBRAL AMYLOID ANGIOPATHY
J. Biol. Chem. 2004 279: 56004-56013. First Published on October 15, 2004; doi:10.1074/jbc.M407283200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Madan Katragadda, Dimitrios Morikis, and John D. Lambris
Thermodynamic Studies on the Interaction of the Third Complement Component and Its Inhibitor, Compstatin
J. Biol. Chem. 2004 279: 54987-54995. First Published on October 15, 2004; doi:10.1074/jbc.M409963200 [Abstract] [Full Text] [PDF]  

Malyasri Bhattacharyya, Sibnath Ray, Shekhar Bhattacharya, and Abhijit Chakrabarti
Chaperone Activity and Prodan Binding at the Self-associating Domain of Erythroid Spectrin
J. Biol. Chem. 2004 279: 55080-55088. First Published on October 18, 2004; doi:10.1074/jbc.M406418200 [Abstract] [Full Text] [PDF]  

Bing-Rui Zhou, Yi Liang, Fen Du, Zheng Zhou, and Jie Chen
Mixed Macromolecular Crowding Accelerates the Oxidative Refolding of Reduced, Denatured Lysozyme: IMPLICATIONS FOR PROTEIN FOLDING IN INTRACELLULAR ENVIRONMENTS
J. Biol. Chem. 2004 279: 55109-55116. First Published on October 19, 2004; doi:10.1074/jbc.M409086200 [Abstract] [Full Text] [PDF]  

Carolina Rausell, Liliana Pardo-López, Jorge Sánchez, Carlos Muñoz-Garay, Claudia Morera, Mario Soberón, and Alejandra Bravo
Unfolding Events in the Water-soluble Monomeric Cry1Ab Toxin during Transition to Oligomeric Pre-pore and Membrane-inserted Pore Channel
J. Biol. Chem. 2004 279: 55168-55175. First Published on October 21, 2004; doi:10.1074/jbc.M406279200 [Abstract] [Full Text] [PDF]  

Yan Chen, Rui Jin, Hong-Yun Dong, and You-Min Feng
In Vitro Refolding/Unfolding Pathways of Amphioxus Insulin-like Peptide: IMPLICATIONS FOR FOLDING BEHAVIOR OF INSULIN FAMILY PROTEINS
J. Biol. Chem. 2004 279: 55224-55233. First Published on October 22, 2004; doi:10.1074/jbc.M409030200 [Abstract] [Full Text] [PDF]  

József Kardos, Kaori Yamamoto, Kazuhiro Hasegawa, Hironobu Naiki, and Yuji Goto
Direct Measurement of the Thermodynamic Parameters of Amyloid Formation by Isothermal Titration Calorimetry
J. Biol. Chem. 2004 279: 55308-55314. First Published on October 19, 2004; doi:10.1074/jbc.M409677200 [Abstract] [Full Text] [PDF]  

Julie A. Saugstad, Jonathan A. Roberts, Jin Dong, Suzanne Zeitouni, and Richard J. Evans
Analysis of the Membrane Topology of the Acid-sensing Ion Channel 2a
J. Biol. Chem. 2004 279: 55514-55519. First Published on October 25, 2004; doi:10.1074/jbc.M411849200 [Abstract] [Full Text] [PDF]  

Maher Al-Ayyoubi, Peter G. W. Gettins, and Karl Volz
Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: REACTIVE CENTER LOOP OF MASPIN IS EXPOSED BUT CONSTRAINED
J. Biol. Chem. 2004 279: 55540-55544. First Published on October 22, 2004; doi:10.1074/jbc.M409957200 [Abstract] [Full Text] [PDF]  

Tung-Ju Hsieh, Lynn Farh, Wai Mun Huang, and Nei-Li Chan
Structure of the Topoisomerase IV C-terminal Domain: A BROKEN {beta}-PROPELLER IMPLIES A ROLE AS GEOMETRY FACILITATOR IN CATALYSIS
J. Biol. Chem. 2004 279: 55587-55593. First Published on October 4, 2004; doi:10.1074/jbc.M408934200 [Abstract] [Full Text] [PDF]  

Triantafyllos Chavakis, Tanja Keiper, Rachel Matz-Westphal, Karin Hersemeyer, Ulrich J. Sachs, Peter P. Nawroth, Klaus T. Preissner, and Sentot Santoso
The Junctional Adhesion Molecule-C Promotes Neutrophil Transendothelial Migration in Vitro and in Vivo
J. Biol. Chem. 2004 279: 55602-55608. First Published on October 14, 2004; doi:10.1074/jbc.M404676200 [Abstract] [Full Text] [PDF]  

Ranjit K. Deka, Lori Neil, Kayla E. Hagman, Mischa Machius, Diana R. Tomchick, Chad A. Brautigam, and Michael V. Norgard
Structural Evidence That the 32-Kilodalton Lipoprotein (Tp32) of Treponema pallidum Is an L-Methionine-binding Protein
J. Biol. Chem. 2004 279: 55644-55650. First Published on October 15, 2004; doi:10.1074/jbc.M409263200 [Abstract] [Full Text] [PDF]  

Imed Regaya, Christine Beeton, Gilles Ferrat, Nicolas Andreotti, Hervé Darbon, Michel De Waard, and Jean-Marc Sabatier
Evidence for Domain-specific Recognition of SK and Kv Channels by MTX and HsTx1 Scorpion Toxins
J. Biol. Chem. 2004 279: 55690-55696. First Published on October 21, 2004; doi:10.1074/jbc.M410055200 [Abstract] [Full Text] [PDF]  

Vladimir M. Korkhov, Hesso Farhan, Michael Freissmuth, and Harald H. Sitte
Oligomerization of the {gamma}-Aminobutyric Acid Transporter-1 Is Driven by an Interplay of Polar and Hydrophobic Interactions in Transmembrane Helix II
J. Biol. Chem. 2004 279: 55728-55736. First Published on October 20, 2004; doi:10.1074/jbc.M409449200 [Abstract] [Full Text] [PDF]  

Mohd. Waseem Akhtar, Volety Srinivas, Bakthisaran Raman, Tangirala Ramakrishna, Tomonao Inobe, Kosuke Maki, Munehito Arai, Kunihiro Kuwajima, and Ch. Mohan Rao
Oligomeric Hsp33 with Enhanced Chaperone Activity: GEL FILTRATION, CROSS-LINKING, AND SMALL ANGLE X-RAY SCATTERING (SAXS) ANALYSIS
J. Biol. Chem. 2004 279: 55760-55769. First Published on October 19, 2004; doi:10.1074/jbc.M406333200 [Abstract] [Full Text] [PDF]  

Ben Sandler, Paul Webb, James W. Apriletti, B. Russell Huber, Marie Togashi, Suzana T. Cunha Lima, Sanja Juric, Stefan Nilsson, Richard Wagner, Robert J. Fletterick, and John D. Baxter
Thyroxine-Thyroid Hormone Receptor Interactions
J. Biol. Chem. 2004 279: 55801-55808. First Published on October 4, 2004; doi:10.1074/jbc.M410124200 [Abstract] [Full Text] [PDF]  

Hanna-Kirsti S. Leiros, Sigrid Kozielski-Stuhrmann, Ulrike Kapp, Laurent Terradot, Gordon A. Leonard, and Seán M. McSweeney
Structural Basis of 5-Nitroimidazole Antibiotic Resistance: THE CRYSTAL STRUCTURE OF NimA FROM DEINOCOCCUS RADIODURANS
J. Biol. Chem. 2004 279: 55840-55849. First Published on October 18, 2004; doi:10.1074/jbc.M408044200 [Abstract] [Full Text] [PDF]  

Michal Hammel, Henri-Pierre Fierobe, Mirjam Czjzek, Stéphanie Finet, and Véronique Receveur-Bréchot
Structural Insights into the Mechanism of Formation of Cellulosomes Probed by Small Angle X-ray Scattering
J. Biol. Chem. 2004 279: 55985-55994. First Published on October 23, 2004; doi:10.1074/jbc.M408979200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

H. Frederik Nijhout, Michael C. Reed, Paula Budu, and Cornelia M. Ulrich
A Mathematical Model of the Folate Cycle: NEW INSIGHTS INTO FOLATE HOMEOSTASIS
J. Biol. Chem. 2004 279: 55008-55016. First Published on October 20, 2004; doi:10.1074/jbc.M410818200 [Abstract] [Full Text] [PDF]  

Dongxia Li, Maija Hirsilä, Peppi Koivunen, Mitchell C. Brenner, Leon Xu, Charles Yang, Kari I. Kivirikko, and Johanna Myllyharju
Many Amino Acid Substitutions in a Hypoxia-inducible Transcription Factor (HIF)-1{alpha}-like Peptide Cause Only Minor Changes in Its Hydroxylation by the HIF Prolyl 4-Hydroxylases: SUBSTITUTION OF 3,4-DEHYDROPROLINE OR AZETIDINE-2-CARBOXYLIC ACID FOR THE PROLINE LEADS TO A HIGH RATE OF UNCOUPLED 2-OXOGLUTARATE DECARBOXYLATION
J. Biol. Chem. 2004 279: 55051-55059. First Published on October 12, 2004; doi:10.1074/jbc.M410287200 [Abstract] [Full Text] [PDF]  

Yuji Honda and Motomitsu Kitaoka
A Family 8 Glycoside Hydrolase from Bacillus halodurans C-125 (BH2105) Is a Reducing End Xylose-releasing Exo-oligoxylanase
J. Biol. Chem. 2004 279: 55097-55103. First Published on October 18, 2004; doi:10.1074/jbc.M409832200 [Abstract] [Full Text] [PDF]  

Mani Maheswaran, Claus Urbanke, and Karl Forchhammer
Complex Formation and Catalytic Activation by the PII Signaling Protein of N-Acetyl-L-glutamate Kinase from Synechococcus elongatus Strain PCC 7942
J. Biol. Chem. 2004 279: 55202-55210. First Published on October 22, 2004; doi:10.1074/jbc.M410971200 [Abstract] [Full Text] [PDF]  

Angel Llamas, Ralf R. Mendel, and Günter Schwarz
Synthesis of Adenylated Molybdopterin: AN ESSENTIAL STEP FOR MOLYBDENUM INSERTION
J. Biol. Chem. 2004 279: 55241-55246. First Published on October 25, 2004; doi:10.1074/jbc.M409862200 [Abstract] [Full Text] [PDF]  

Hideyuki Kumita, Koji Matsuura, Tomoya Hino, Satoshi Takahashi, Hiroshi Hori, Yoshihiro Fukumori, Isao Morishima, and Yoshitsugu Shiro
NO Reduction by Nitric-oxide Reductase from Denitrifying Bacterium Pseudomonas aeruginosa: CHARACTERIZATION OF REACTION INTERMEDIATES THAT APPEAR IN THE SINGLE TURNOVER CYCLE
J. Biol. Chem. 2004 279: 55247-55254. First Published on October 25, 2004; doi:10.1074/jbc.M409996200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

J. Carlos Aledo and Alicia Esteban del Valle
The ATP Paradox Is the Expression of an Economizing Fuel Mechanism
J. Biol. Chem. 2004 279: 55372-55375. First Published on October 27, 2004; doi:10.1074/jbc.M410479200 [Abstract] [Full Text] [PDF] Supplemental Data  

Blanca Rubi, Araceli del Arco, Clarissa Bartley, Jorgina Satrustegui, and Pierre Maechler
The Malate-Aspartate NADH Shuttle Member Aralar1 Determines Glucose Metabolic Fate, Mitochondrial Activity, and Insulin Secretion in Beta Cells
J. Biol. Chem. 2004 279: 55659-55666. First Published on October 19, 2004; doi:10.1074/jbc.M409303200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Wuyi Kong, Michael T. Longaker, and H. Peter Lorenz
Cyclophilin C-associated Protein Is a Mediator for Fibronectin Fragment-induced Matrix Metalloproteinase-13 Expression
J. Biol. Chem. 2004 279: 55334-55340. First Published on October 26, 2004; doi:10.1074/jbc.M410804200 [Abstract] [Full Text] [PDF]  

Michael A. Held, Li Tan, Abdolreza Kamyab, Michael Hare, Elena Shpak, and Marcia J. Kieliszewski
Di-isodityrosine Is the Intermolecular Cross-link of Isodityrosine-rich Extensin Analogs Cross-linked in Vitro
J. Biol. Chem. 2004 279: 55474-55482. First Published on October 1, 2004; doi:10.1074/jbc.M408396200 [Abstract] [Full Text] [PDF] Supplemental Data  

Astrid Blume, Andrew J. Benie, Florian Stolz, Richard R. Schmidt, Werner Reutter, Stephan Hinderlich, and Thomas Peters
Characterization of Ligand Binding to the Bifunctional Key Enzyme in the Sialic Acid Biosynthesis by NMR: I. INVESTIGATION OF THE UDP-GlcNAc 2-EPIMERASE FUNCTIONALITY
J. Biol. Chem. 2004 279: 55715-55721. First Published on October 21, 2004; doi:10.1074/jbc.M410238200 [Abstract] [Full Text] [PDF]  

Andrew J. Benie, Astrid Blume, Richard R. Schmidt, Werner Reutter, Stephan Hinderlich, and Thomas Peters
Characterization of Ligand Binding to the Bifunctional Key Enzyme in the Sialic Acid Biosynthesis by NMR: II. INVESTIGATION OF THE ManNAc KINASE FUNCTIONALITY
J. Biol. Chem. 2004 279: 55722-55727. First Published on October 21, 2004; doi:10.1074/jbc.M410239200 [Abstract] [Full Text] [PDF]  

Juha-Pekka Pitkänen, Anssi Törmä, Susanne Alff, Laura Huopaniemi, Pirkko Mattila, and Risto Renkonen
Excess Mannose Limits the Growth of Phosphomannose Isomerase PMI40 Deletion Strain of Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 55737-55743. First Published on November 1, 2004; doi:10.1074/jbc.M410619200 [Abstract] [Full Text] [PDF] Supplemental Data  

Harri Altroff, Robin Schlinkert, Christopher F. van der Walle, Andrea Bernini, Iain D. Campbell, Jörn M. Werner, and Helen J. Mardon
Interdomain Tilt Angle Determines Integrin-dependent Function of the Ninth and Tenth FIII Domains of Human Fibronectin
J. Biol. Chem. 2004 279: 55995-56003. First Published on October 12, 2004; doi:10.1074/jbc.M406976200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Caroline H. O'Neil, Michael B. Boffa, Mark A. Hancock, J. Geoffrey Pickering, and Marlys L. Koschinsky
Stimulation of Vascular Smooth Muscle Cell Proliferation and Migration by Apolipoprotein(a) Is Dependent on Inhibition of Transforming Growth Factor-{beta} Activation and on the Presence of Kringle IV Type 9
J. Biol. Chem. 2004 279: 55187-55195. First Published on October 21, 2004; doi:10.1074/jbc.M409860200 [Abstract] [Full Text] [PDF]  

Eva M. Madsen, Marie L. S. Lindegaard, Claus B. Andersen, Peter Damm, and Lars B. Nielsen
Human Placenta Secretes Apolipoprotein B-100-containing Lipoproteins
J. Biol. Chem. 2004 279: 55271-55276. First Published on October 25, 2004; doi:10.1074/jbc.M411404200 [Abstract] [Full Text] [PDF]  

Joerg Heeren, Thomas Grewal, Alexander Laatsch, Nils Becker, Franz Rinninger, Kerry-Anne Rye, and Ulrike Beisiegel
Impaired Recycling of Apolipoprotein E4 Is Associated with Intracellular Cholesterol Accumulation
J. Biol. Chem. 2004 279: 55483-55492. First Published on October 12, 2004; doi:10.1074/jbc.M409324200 [Abstract] [Full Text] [PDF]  

An X. Tran, Mark J. Karbarz, Xiaoyuan Wang, Christian R. H. Raetz, Sara C. McGrath, Robert J. Cotter, and M. Stephen Trent
Periplasmic Cleavage and Modification of the 1-Phosphate Group of Helicobacter pylori Lipid A
J. Biol. Chem. 2004 279: 55780-55791. First Published on October 15, 2004; doi:10.1074/jbc.M406480200 [Abstract] [Full Text] [PDF]  

Yanzhu Yang, Jingsong Cao, and Yuguang Shi
Identification and Characterization of a Gene Encoding Human LPGAT1, an Endoplasmic Reticulum-associated Lysophosphatidylglycerol Acyltransferase
J. Biol. Chem. 2004 279: 55866-55874. First Published on October 12, 2004; doi:10.1074/jbc.M406710200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ross Ridsdale, Irene Tseu, Matthias Roth-Kleiner, Jinxia Wang, and Martin Post
Increased Phosphatidylcholine Production but Disrupted Glycogen Metabolism in Fetal Type II Cells of Mice That Overexpress CTP:Phosphocholine Cytidylyltransferase
J. Biol. Chem. 2004 279: 55946-55957. First Published on October 21, 2004; doi:10.1074/jbc.M407670200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:

Deanne H. Hryciw, Jenny Ekberg, Aven Lee, Ingrid L. Lensink, Sharad Kumar, William B. Guggino, David I. Cook, Carol A. Pollock, and Philip Poronnik
Nedd4-2 Functionally Interacts with ClC-5: INVOLVEMENT IN CONSTITUTIVE ALBUMIN ENDOCYTOSIS IN PROXIMAL TUBULE CELLS
J. Biol. Chem. 2004 279: 54996-55007. First Published on October 15, 2004; doi:10.1074/jbc.M411491200 [Abstract] [Full Text] [PDF]  

Neeta Asthana, Sharada Prasad Yadav, and Jimut Kanti Ghosh
Dissection of Antibacterial and Toxic Activity of Melittin: A LEUCINE ZIPPER MOTIF PLAYS A CRUCIAL ROLE IN DETERMINING ITS HEMOLYTIC ACTIVITY BUT NOT ANTIBACTERIAL ACTIVITY
J. Biol. Chem. 2004 279: 55042-55050. First Published on October 8, 2004; doi:10.1074/jbc.M408881200 [Abstract] [Full Text] [PDF]  

Johann Hertel, Heidi Struthers, Christal Baird Horj, and Paul W. Hruz
A Structural Basis for the Acute Effects of HIV Protease Inhibitors on GLUT4 Intrinsic Activity
J. Biol. Chem. 2004 279: 55147-55152. First Published on October 20, 2004; doi:10.1074/jbc.M410826200 [Abstract] [Full Text] [PDF]  

Ning Ge, Chantal N. Muise, Xiandi Gong, and Paul Linsdell
Direct Comparison of the Functional Roles Played by Different Transmembrane Regions in the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore
J. Biol. Chem. 2004 279: 55283-55289. First Published on October 25, 2004; doi:10.1074/jbc.M411935200 [Abstract] [Full Text] [PDF]  

Edward Spence, Shaun Bailey, Anja Nenninger, Simon Geir Møller, and Colin Robinson
A Homolog of Albino3/OxaI Is Essential for Thylakoid Biogenesis in the Cyanobacterium Synechocystis sp. PCC6803
J. Biol. Chem. 2004 279: 55792-55800. First Published on October 21, 2004; doi:10.1074/jbc.M411041200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Didi Baev, Alberto Rivetta, Slavena Vylkova, Jianing N. Sun, Ge-Fei Zeng, Clifford L. Slayman, and Mira Edgerton
The TRK1 Potassium Transporter Is the Critical Effector for Killing of Candida albicans by the Cationic Protein, Histatin 5
J. Biol. Chem. 2004 279: 55060-55072. First Published on October 13, 2004; doi:10.1074/jbc.M411031200 [Abstract] [Full Text] [PDF]  

Michael G. Tomlinson, Victoria L. Heath, Chris W. Turck, Steve P. Watson, and Arthur Weiss
SHIP Family Inositol Phosphatases Interact with and Negatively Regulate the Tec Tyrosine Kinase
J. Biol. Chem. 2004 279: 55089-55096. First Published on October 18, 2004; doi:10.1074/jbc.M408141200 [Abstract] [Full Text] [PDF]  

Keishi Yamauchi, Yoshihiro Nishimura, Satoshi Shigematsu, Yuichiro Takeuchi, Junko Nakamura, Toru Aizawa, and Kiyoshi Hashizume
Vascular Endothelial Cell Growth Factor Attenuates Actions of Transforming Growth Factor-{beta} in Human Endothelial Cells
J. Biol. Chem. 2004 279: 55104-55108. First Published on October 19, 2004; doi:10.1074/jbc.M407423200 [Abstract] [Full Text] [PDF]  

Sushil Kumar Pathak, Asima Bhattacharyya, Shresh Pathak, Chaitali Basak, Debabrata Mandal, Manikuntala Kundu, and Joyoti Basu
Toll-like Receptor 2 and Mitogen- and Stress-activated Kinase 1 Are Effectors of Mycobacterium avium-induced Cyclooxygenase-2 Expression in Macrophages
J. Biol. Chem. 2004 279: 55127-55136. First Published on October 20, 2004; doi:10.1074/jbc.M409885200 [Abstract] [Full Text] [PDF]  

Qitao Ran, Hanyu Liang, Minjun Gu, Wenbo Qi, Christi A. Walter, L. Jackson Roberts, II, Brian Herman, Arlan Richardson, and Holly Van Remmen
Transgenic Mice Overexpressing Glutathione Peroxidase 4 Are Protected against Oxidative Stress-induced Apoptosis
J. Biol. Chem. 2004 279: 55137-55146. First Published on October 20, 2004; doi:10.1074/jbc.M410387200 [Abstract] [Full Text] [PDF]  

William Reiley, Minying Zhang, and Shao-Cong Sun
Negative Regulation of JNK Signaling by the Tumor Suppressor CYLD
J. Biol. Chem. 2004 279: 55161-55167. First Published on October 20, 2004; doi:10.1074/jbc.M411049200 [Abstract] [Full Text] [PDF]  

Huie Jing, Jui-Hung Yen, and Doina Ganea
A Novel Signaling Pathway Mediates the Inhibition of CCL3/4 Expression by Prostaglandin E2
J. Biol. Chem. 2004 279: 55176-55186. First Published on October 21, 2004; doi:10.1074/jbc.M409816200 [Abstract] [Full Text] [PDF]  

Irene G. Huber, Edwin Wappl-Kornherr, Martina J. Sinnegger-Brauns, Jean-Charles Hoda, Doris Walter-Bastl, and Jörg Striessnig
Opposite Effects of a Single IIIS5 Mutation on Phenylalkylamine and Dihydropyridine Interaction with L-type Ca2+ Channels
J. Biol. Chem. 2004 279: 55211-55217. First Published on October 25, 2004; doi:10.1074/jbc.M409008200 [Abstract] [Full Text] [PDF]  

Irwan T. Makagiansar, Scott Williams, Kimberlee Dahlin-Huppe, Jun-ichi Fukushi, Tomas Mustelin, and William B. Stallcup
Phosphorylation of NG2 Proteoglycan by Protein Kinase C-{alpha} Regulates Polarized Membrane Distribution and Cell Motility
J. Biol. Chem. 2004 279: 55262-55270. First Published on October 25, 2004; doi:10.1074/jbc.M411045200 [Abstract] [Full Text] [PDF]  

Akiyoshi Shimaya, Kristina S. Kovacina, and Richard A. Roth
On the Mechanism for Neomycin Reversal of Wortmannin Inhibition of Insulin Stimulation of Glucose Uptake
J. Biol. Chem. 2004 279: 55277-55282. First Published on October 25, 2004; doi:10.1074/jbc.M411540200 [Abstract] [Full Text] [PDF]  

Yongyou Zhang, Yongshun Lin, Courtney Bowles, and Fen Wang
Direct Cell Cycle Regulation by the Fibroblast Growth Factor Receptor (FGFR) Kinase through Phosphorylation-dependent Release of Cks1 from FGFR Substrate 2
J. Biol. Chem. 2004 279: 55348-55354. First Published on October 27, 2004; doi:10.1074/jbc.M409230200 [Abstract] [Full Text] [PDF] Supplemental Data  

Alicia Monjas, Andrés Alcover, and Balbino Alarcón
Engaged and Bystander T Cell Receptors Are Down-modulated by Different Endocytotic Pathways
J. Biol. Chem. 2004 279: 55376-55384. First Published on October 28, 2004; doi:10.1074/jbc.M409342200 [Abstract] [Full Text] [PDF]  

Sevgi Eminel, Alexa Klettner, Lutz Roemer, Thomas Herdegen, and Vicki Waetzig
JNK2 Translocates to the Mitochondria and Mediates Cytochrome c Release in PC12 Cells in Response to 6-Hydroxydopamine
J. Biol. Chem. 2004 279: 55385-55392. First Published on October 25, 2004; doi:10.1074/jbc.M405858200 [Abstract] [Full Text] [PDF]  

Jun Tanikawa, Teruaki Nomura, Elizabeth M. Macmillan, Toshie Shinagawa, Wanzhu Jin, Kenji Kokura, Daichi Baba, Masahiro Shirakawa, Thomas J. Gonda, and Shunsuke Ishii
p53 Suppresses c-Myb-induced trans-Activation and Transformation by Recruiting the Corepressor mSin3A
J. Biol. Chem. 2004 279: 55393-55400. First Published on October 27, 2004; doi:10.1074/jbc.M411658200 [Abstract] [Full Text] [PDF] Supplemental Data  

Lan Ge, Sudha K. Shenoy, Robert J. Lefkowitz, and Kathryn DeFea
Constitutive Protease-activated Receptor-2-mediated Migration of MDA MB-231 Breast Cancer Cells Requires Both {beta}-Arrestin-1 and -2
J. Biol. Chem. 2004 279: 55419-55424. First Published on October 14, 2004; doi:10.1074/jbc.M410312200 [Abstract] [Full Text] [PDF] Supplemental Data  

Erich Durchschlag, Wolfgang Reiter, Gustav Ammerer, and Christoph Schüller
Nuclear Localization Destabilizes the Stress-regulated Transcription Factor Msn2
J. Biol. Chem. 2004 279: 55425-55432. First Published on October 22, 2004; doi:10.1074/jbc.M407264200 [Abstract] [Full Text] [PDF] [Papers Of The Week]  

Annemieke A. de Melker, Gerda van der Horst, and Jannie Borst
Ubiquitin Ligase Activity of c-Cbl Guides the Epidermal Growth Factor Receptor into Clathrin-coated Pits by Two Distinct Modes of Eps15 Recruitment
J. Biol. Chem. 2004 279: 55465-55473. First Published on October 1, 2004; doi:10.1074/jbc.M409765200 [Abstract] [Full Text] [PDF]  

Takahiko Shiina, Akihiro Konno, Toshina Oonuma, Hiroshi Kitamura, Koichi Imaoka, Naoki Takeda, Kazuo Todokoro, and Masami Morimatsu
Targeted Disruption of MAIL, a Nuclear I{kappa}B Protein, Leads to Severe Atopic Dermatitis-like Disease
J. Biol. Chem. 2004 279: 55493-55498. First Published on October 18, 2004; doi:10.1074/jbc.M409770200 [Abstract] [Full Text] [PDF]  

Guang Yu, Hongyu Luo, Yulian Wu, and Jiangping Wu
EphrinB1 Is Essential in T-cell-T-cell Co-operation during T-cell Activation
J. Biol. Chem. 2004 279: 55531-55539. First Published on October 22, 2004; doi:10.1074/jbc.M410814200 [Abstract] [Full Text] [PDF]  

JianFeng Chen, Junichi Takagi, Can Xie, Tsan Xiao, Bing-Hao Luo, and Timothy A. Springer
The Relative Influence of Metal Ion Binding Sites in the I-like Domain and the Interface with the Hybrid Domain on Rolling and Firm Adhesion by Integrin {alpha}4{beta}7
J. Biol. Chem. 2004 279: 55556-55561. First Published on September 24, 2004; doi:10.1074/jbc.M407773200 [Abstract] [Full Text] [PDF]  

Tai-Guang Jin, Alexei Kurakin, Nordine Benhaga, Karon Abe, Mehrdad Mohseni, Ferry Sandra, Keli Song, Brian K. Kay, and Roya Khosravi-Far
Fas-associated Protein with Death Domain (FADD)-independent Recruitment of c-FLIPL to Death Receptor 5
J. Biol. Chem. 2004 279: 55594-55601. First Published on October 14, 2004; doi:10.1074/jbc.M401056200 [Abstract] [Full Text] [PDF]  

Jianguo Liu, Xiuqin Guan, Tomohiko Tamura, Keiko Ozato, and Xiaojing Ma
Synergistic Activation of Interleukin-12 p35 Gene Transcription by Interferon Regulatory Factor-1 and Interferon Consensus Sequence-binding Protein
J. Biol. Chem. 2004 279: 55609-55617. First Published on October 15, 2004; doi:10.1074/jbc.M406565200 [Abstract] [Full Text] [PDF]  

Holger Buss, Anneke Dörrie, M. Lienhard Schmitz, Elke Hoffmann, Klaus Resch, and Michael Kracht
Constitutive and Interleukin-1-inducible Phosphorylation of p65 NF-{kappa}B at Serine 536 Is Mediated by Multiple Protein Kinases Including I{kappa}B Kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF Family Member-associated (TANK)-binding Kinase 1 (TBK1), and an Unknown Kinase and Couples p65 to TATA-binding Protein-associated Factor II31-mediated Interleukin-8 Transcription
J. Biol. Chem. 2004 279: 55633-55643. First Published on October 15, 2004; doi:10.1074/jbc.M409825200 [Abstract] [Full Text] [PDF]  

Jean-Christophe Peter, Gerd Wallukat, Jean Tugler, Damien Maurice, Jean-Christophe Roegel, Jean-Paul Briand, and Johan Hoebeke
Modulation of the M2 Muscarinic Acetylcholine Receptor Activity with Monoclonal Anti-M2 Receptor Antibody Fragments
J. Biol. Chem. 2004 279: 55697-55706. First Published on October 14, 2004; doi:10.1074/jbc.M407213200 [Abstract] [Full Text] [PDF]  

Kunhong Xiao, Sudha K. Shenoy, Kelly Nobles, and Robert J. Lefkowitz
Activation-dependent Conformational Changes in {beta}-Arrestin 2
J. Biol. Chem. 2004 279: 55744-55753. First Published on October 22, 2004; doi:10.1074/jbc.M409785200 [Abstract] [Full Text] [PDF]  

Mario D. Galigniana, Yoshihiro Morishima, Philippe A. Gallay, and William B. Pratt
Cyclophilin-A Is Bound through Its Peptidylprolyl Isomerase Domain to the Cytoplasmic Dynein Motor Protein Complex
J. Biol. Chem. 2004 279: 55754-55759. First Published on October 20, 2004; doi:10.1074/jbc.M406259200 [Abstract] [Full Text] [PDF]  

Xiaolu Zou, Jeffrey R. Seemann, Dawn Neuman, and Qingxi J. Shen
A WRKY Gene from Creosote Bush Encodes an Activator of the Abscisic Acid Signaling Pathway
J. Biol. Chem. 2004 279: 55770-55779. First Published on October 25, 2004; doi:10.1074/jbc.M408536200 [Abstract] [Full Text] [PDF]  

Marc T. Abrams, Noreen M. Robertson, Kyonggeun Yoon, and Eric Wickstrom
Inhibition of Glucocorticoid-induced Apoptosis by Targeting the Major Splice Variants of BIM mRNA with Small Interfering RNA and Short Hairpin RNA
J. Biol. Chem. 2004 279: 55809-55817. First Published on October 27, 2004; doi:10.1074/jbc.M411767200 [Abstract] [Full Text] [PDF]  

Emmanuelle M. Six, Delphine Ndiaye, Guido Sauer, Yacine Laâbi, Rafika Athman, Ana Cumano, Christel Brou, Alain Israël, and Frédérique Logeat
The Notch Ligand Delta1 Recruits Dlg1 at Cell-Cell Contacts and Regulates Cell Migration
J. Biol. Chem. 2004 279: 55818-55826. First Published on October 14, 2004; doi:10.1074/jbc.M408022200 [Abstract] [Full Text] [PDF] Supplemental Data  

Shane Atwell, Jason M. Adams, John Badger, Michelle D. Buchanan, Ingeborg K. Feil, Karen J. Froning, Xia Gao, Jörg Hendle, Kevin Keegan, Barbara C. Leon, Hans J. Müller-Dieckmann, Vicki L. Nienaber, Brian W. Noland, Kai Post, K. R. Rajashankar, Aurora Ramos, Marijane Russell, Stephen K. Burley, and Sean G. Buchanan
A Novel Mode of Gleevec Binding Is Revealed by the Structure of Spleen Tyrosine Kinase
J. Biol. Chem. 2004 279: 55827-55832. First Published on October 26, 2004; doi:10.1074/jbc.M409792200 [Abstract] [Full Text] [PDF]  

Anja Schneider, Gilda Wright Araújo, Katarina Trajkovic, Martin M. Herrmann, Doron Merkler, Eva-Maria Mandelkow, Robert Weissert, and Mikael Simons
Hyperphosphorylation and Aggregation of Tau in Experimental Autoimmune Encephalomyelitis
J. Biol. Chem. 2004 279: 55833-55839. First Published on October 19, 2004; doi:10.1074/jbc.M409954200 [Abstract] [Full Text] [PDF]  

Liusheng He, Amrie C. Grammer, Xiaoli Wu, and Peter E. Lipsky
TRAF3 Forms Heterotrimers with TRAF2 and Modulates Its Ability to Mediate NF-{kappa}B Activation
J. Biol. Chem. 2004 279: 55855-55865. First Published on September 21, 2004; doi:10.1074/jbc.M407284200 [Abstract] [Full Text] [PDF]  

Pao-Chen Kuo, Huei-Fang Liu, and Jui-I Chao
Survivin and p53 Modulate Quercetin-induced Cell Growth Inhibition and Apoptosis in Human Lung Carcinoma Cells
J. Biol. Chem. 2004 279: 55875-55885. First Published on September 29, 2004; doi:10.1074/jbc.M407985200 [Abstract] [Full Text] [PDF]  

Jay M. Janz and David L. Farrens
Role of the Retinal Hydrogen Bond Network in Rhodopsin Schiff Base Stability and Hydrolysis
J. Biol. Chem. 2004 279: 55886-55894. First Published on October 8, 2004; doi:10.1074/jbc.M408766200 [Abstract] [Full Text] [PDF]  

Koh-ichi Nagata, Tomiko Asano, Yoshinori Nozawa, and Masaki Inagaki
Biochemical and Cell Biological Analyses of a Mammalian Septin Complex, Sept7/9b/11
J. Biol. Chem. 2004 279: 55895-55904. First Published on October 12, 2004; doi:10.1074/jbc.M406153200 [Abstract] [Full Text] [PDF]  

Huimiao Jiang, Andrew S. Weyrich, Guy A. Zimmerman, and Thomas M. McIntyre
Endothelial Cell Confluence Regulates Cyclooxygenase-2 and Prostaglandin E2 Production That Modulate Motility
J. Biol. Chem. 2004 279: 55905-55913. First Published on October 13, 2004; doi:10.1074/jbc.M406094200 [Abstract] [Full Text] [PDF]  

Jiang Liu, Stephen A. Ernst, Svetlana E. Gladycheva, Yue Ying F. Lee, Stephen I. Lentz, Chi S. Ho, Quanwen Li, and Edward L. Stuenkel
Fluorescence Resonance Energy Transfer Reports Properties of Syntaxin1A Interaction with Munc18-1 in Vivo
J. Biol. Chem. 2004 279: 55924-55936. First Published on October 15, 2004; doi:10.1074/jbc.M410024200 [Abstract] [Full Text] [PDF]  

Qing Luo, Quan Kang, Weike Si, Wei Jiang, Jong Kyung Park, Ying Peng, Xinmin Li, Hue H. Luu, Jeffrey Luo, Anthony G. Montag, Rex C. Haydon, and Tong-Chuan He
Connective Tissue Growth Factor (CTGF) Is Regulated by Wnt and Bone Morphogenetic Proteins Signaling in Osteoblast Differentiation of Mesenchymal Stem Cells
J. Biol. Chem. 2004 279: 55958-55968. First Published on October 20, 2004; doi:10.1074/jbc.M407810200 [Abstract] [Full Text] [PDF]  

Bart Lesage, Monique Beullens, Mieke Nuytten, Aleyde Van Eynde, Stefaan Keppens, Bernard Himpens, and Mathieu Bollen
Interactor-mediated Nuclear Translocation and Retention of Protein Phosphatase-1
J. Biol. Chem. 2004 279: 55978-55984. First Published on October 22, 2004; doi:10.1074/jbc.M411911200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Subhradip Karmakar, Ruby Dhar, and Chandana Das
Inhibition of Cytotrophoblastic (JEG-3) Cell Invasion by Interleukin 12 Involves an Interferon {gamma}-mediated Pathway
J. Biol. Chem. 2004 279: 55297-55307. First Published on September 23, 2004; doi:10.1074/jbc.M407013200 [Abstract] [Full Text] [PDF]  

Richard Bayly, Luan Chuen, Richard A. Currie, Brandy D. Hyndman, Richard Casselman, Gerd A. Blobel, and David P. LeBrun
E2A-PBX1 Interacts Directly with the KIX Domain of CBP/p300 in the Induction of Proliferation in Primary Hematopoietic Cells
J. Biol. Chem. 2004 279: 55362-55371. First Published on October 26, 2004; doi:10.1074/jbc.M408654200 [Abstract] [Full Text] [PDF] Supplemental Data  

Sanjeev Puri, Brenda S. Magenheimer, Robin L. Maser, Erin M. Ryan, Christopher A. Zien, Danielle D. Walker, Darren P. Wallace, Scott J. Hempson, and James P. Calvet
Polycystin-1 Activates the Calcineurin/NFAT (Nuclear Factor of Activated T-cells) Signaling Pathway
J. Biol. Chem. 2004 279: 55455-55464. First Published on October 5, 2004; doi:10.1074/jbc.M402905200 [Abstract] [Full Text] [PDF]  

Daniel R. Clayburgh, Shari Rosen, Edwina D. Witkowski, Fengjun Wang, Stephanie Blair, Steven Dudek, Joe G. N. Garcia, John C. Alverdy, and Jerrold R. Turner
A Differentiation-dependent Splice Variant of Myosin Light Chain Kinase, MLCK1, Regulates Epithelial Tight Junction Permeability
J. Biol. Chem. 2004 279: 55506-55513. First Published on October 26, 2004; doi:10.1074/jbc.M408822200 [Abstract] [Full Text] [PDF]  

Frédérique Paulhe, Beat A. Imhof, and Bernhard Wehrle-Haller
A Specific Endoplasmic Reticulum Export Signal Drives Transport of Stem Cell Factor (Kitl) to the Cell Surface
J. Biol. Chem. 2004 279: 55545-55555. First Published on October 8, 2004; doi:10.1074/jbc.M407813200 [Abstract] [Full Text] [PDF] Supplemental Data  

Soichi Nakata, Itaru Matsumura, Hirokazu Tanaka, Sachiko Ezoe, Yusuke Satoh, Jun Ishikawa, Takumi Era, and Yuzuru Kanakura
NF-{kappa}B Family Proteins Participate in Multiple Steps of Hematopoiesis through Elimination of Reactive Oxygen Species
J. Biol. Chem. 2004 279: 55578-55586. First Published on October 13, 2004; doi:10.1074/jbc.M408238200 [Abstract] [Full Text] [PDF]  

Kasuen Wong, Junyu Zhang, Soumya Awasthi, Anima Sharma, Lowery Rogers, Elizabeth F. Matlock, Carine Van Lint, Tatiana Karpova, James McNally, and Robert Harrod
Nerve Growth Factor Receptor Signaling Induces Histone Acetyltransferase Domain-dependent Nuclear Translocation of p300/CREB-binding Protein-associated Factor and hGCN5 Acetyltransferases
J. Biol. Chem. 2004 279: 55667-55674. First Published on October 20, 2004; doi:10.1074/jbc.M408174200 [Abstract] [Full Text] [PDF]  

Karsten Grote, Udo Bavendiek, Christina Grothusen, Inna Flach, Denise Hilfiker-Kleiner, Helmut Drexler, and Bernhard Schieffer
Stretch-inducible Expression of the Angiogenic Factor CCN1 in Vascular Smooth Muscle Cells Is Mediated by Egr-1
J. Biol. Chem. 2004 279: 55675-55681. First Published on October 18, 2004; doi:10.1074/jbc.M406532200 [Abstract] [Full Text] [PDF]  

Chris I. Turnbull, Ken Looi, Jonathan E. Mangum, Michael Meyer, Rod J. Sayer, and Michael J. Hubbard
Calbindin Independence of Calcium Transport in Developing Teeth Contradicts the Calcium Ferry Dogma
J. Biol. Chem. 2004 279: 55850-55854. First Published on October 19, 2004; doi:10.1074/jbc.M409299200 [Abstract] [Full Text] [PDF]  

Weisong Shan, Yoshiki Yagita, Zhaohui Wang, Alexander Koch, Asa Fex Svenningsen, Eugenia Gruzglin, Liliana Pedraza, and David R. Colman
The Minimal Essential Unit for Cadherin-mediated Intercellular Adhesion Comprises Extracellular Domains 1 and 2
J. Biol. Chem. 2004 279: 55914-55923. First Published on October 14, 2004; doi:10.1074/jbc.M407827200 [Abstract] [Full Text] [PDF]  

Karine Andreau, Maria Castedo, Jean-Luc Perfettini, Thomas Roumier, Evelyne Pichart, Sylvie Souquere, Sonia Vivet, Nathanael Larochette, and Guido Kroemer
Preapoptotic Chromatin Condensation Upstream of the Mitochondrial Checkpoint
J. Biol. Chem. 2004 279: 55937-55945. First Published on October 21, 2004; doi:10.1074/jbc.M406411200 [Abstract] [Full Text] [PDF]  

Dominique Helmlinger, Jacques Bonnet, Jean-Louis Mandel, Yvon Trottier, and Didier Devys
Hsp70 and Hsp40 Chaperones Do Not Modulate Retinal Phenotype in SCA7 Mice
J. Biol. Chem. 2004 279: 55969-55977. First Published on October 19, 2004; doi:10.1074/jbc.M409062200 [Abstract] [Full Text] [PDF] [Papers Of The Week]  

Sandy D. Westerheide, Joshua D. Bosman, Bessie N. A. Mbadugha, Tiara L. A. Kawahara, Gen Matsumoto, Soojin Kim, Wenxin Gu, John P. Devlin, Richard B. Silverman, and Richard I. Morimoto
Celastrols as Inducers of the Heat Shock Response and Cytoprotection
J. Biol. Chem. 2004 279: 56053-56060. First Published on October 26, 2004; doi:10.1074/jbc.M409267200 [Abstract] [Full Text] [PDF] Supplemental Data  

Sharon Benzeno and J. Alan Diehl
C-terminal Sequences Direct Cyclin D1-CRM1 Binding
J. Biol. Chem. 2004 279: 56061-56066. First Published on October 28, 2004; doi:10.1074/jbc.M411910200 [Abstract] [Full Text] [PDF]  


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