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Table of Contents: Feb 13 2004; 279 (7)   [Index by Author]  [Cover Figure and Caption]
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Genomics, Proteomics, and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Accelerated Publications:

Sabine Häcker and Heike Krebber
Differential Export Requirements for Shuttling Serine/Arginine-type mRNA-binding Proteins
J. Biol. Chem. 2004 279: 5049-5052. First Published on December 15, 2003; doi:10.1074/jbc.C300522200 [Abstract] [Full Text] [PDF]  

Balagurunathan Kuberan, Miroslaw Lech, Jimo Borjigin, and Robert D. Rosenberg
Light-induced 3-O-Sulfotransferase Expression Alters Pineal Heparan Sulfate Fine Structure: A SURPRISING LINK TO CIRCADIAN RHYTHM
J. Biol. Chem. 2004 279: 5053-5054. First Published on November 20, 2003; doi:10.1074/jbc.C300492200 [Abstract] [Full Text] [PDF]  

Erzsébet Ligeti, Marie-Claire Dagher, Samuel E. Hernandez, Anthony J. Koleske, and Jeffrey Settleman
Phospholipids Can Switch the GTPase Substrate Preference of a GTPase-activating Protein
J. Biol. Chem. 2004 279: 5055-5058. First Published on December 29, 2003; doi:10.1074/jbc.C300547200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:

Tanya L. Williams and Tania A. Baker
Reorganization of the Mu Transpososome Active Sites during a Cooperative Transition between DNA Cleavage and Joining
J. Biol. Chem. 2004 279: 5135-5145. First Published on October 29, 2003; doi:10.1074/jbc.M308156200 [Abstract] [Full Text] [PDF] Supplemental Data  

Maria Malanga and Felix R. Althaus
Poly(ADP-ribose) Reactivates Stalled DNA Topoisomerase I and Induces DNA Strand Break Resealing
J. Biol. Chem. 2004 279: 5244-5248. First Published on December 29, 2003; doi:10.1074/jbc.C300437200 [Abstract] [Full Text] [PDF]  

Suveena Sharma, Bangalore K. Sathyanarayana, Jeremy G. Bird, Joel R. Hoskins, Byungkook Lee, and Sue Wickner
Plasmid P1 RepA Is Homologous to the F Plasmid RepE Class of Initiators
J. Biol. Chem. 2004 279: 6027-6034. First Published on November 21, 2003; doi:10.1074/jbc.M310917200 [Abstract] [Full Text] [PDF]  

Su-Jung Park, Samantha L. M. Ciccone, Brian Freie, Akihiro Kurimasa, David J. Chen, Gloria C. Li, D. Wade Clapp, and Suk-Hee Lee
A Positive Role for the Ku Complex in DNA Replication Following Strand Break Damage in Mammals
J. Biol. Chem. 2004 279: 6046-6055. First Published on November 15, 2003; doi:10.1074/jbc.M311054200 [Abstract] [Full Text] [PDF]  

Jill S. Bleuit, Yujie Ma, James Munro, and Scott W. Morrical
Mutations in a Conserved Motif Inhibit Single-stranded DNA Binding and Recombination Mediator Activities of Bacteriophage T4 UvsY Protein
J. Biol. Chem. 2004 279: 6077-6086. First Published on November 22, 2003; doi:10.1074/jbc.M311557200 [Abstract] [Full Text] [PDF]  

Xiangbing Meng, Yuan Yuan, Adrian Maestas, and Zhiyuan Shen
Recovery from DNA Damage-induced G2 Arrest Requires Actin-binding Protein Filamin-A/Actin-binding Protein 280
J. Biol. Chem. 2004 279: 6098-6105. First Published on December 1, 2003; doi:10.1074/jbc.M306794200 [Abstract] [Full Text] [PDF]  

Dawn M. Clifford, Suzanne M. Marinco, and George S. Brush
The Meiosis-specific Protein Kinase Ime2 Directs Phosphorylation of Replication Protein A
J. Biol. Chem. 2004 279: 6163-6170. First Published on November 21, 2003; doi:10.1074/jbc.M306943200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Christoph Kramps, Verena Strieder, Alexandra Sapetschnig, Guntram Suske, and Werner Lutz
E2F and Sp1/Sp3 Synergize but Are Not Sufficient to Activate the MYCN Gene in Neuroblastomas
J. Biol. Chem. 2004 279: 5110-5117. First Published on November 26, 2003; doi:10.1074/jbc.M304758200 [Abstract] [Full Text] [PDF]  

Michael B. Major and David A. Jones
Identification of a gadd45{beta} 3' Enhancer That Mediates SMAD3- and SMAD4-dependent Transcriptional Induction by Transforming Growth Factor {beta}
J. Biol. Chem. 2004 279: 5278-5287. First Published on November 20, 2003; doi:10.1074/jbc.M311517200 [Abstract] [Full Text] [PDF] Supplemental Data  

Julien Averous, Alain Bruhat, Céline Jousse, Valérie Carraro, Gerald Thiel, and Pierre Fafournoux
Induction of CHOP Expression by Amino Acid Limitation Requires Both ATF4 Expression and ATF2 Phosphorylation
J. Biol. Chem. 2004 279: 5288-5297. First Published on December 1, 2003; doi:10.1074/jbc.M311862200 [Abstract] [Full Text] [PDF]  

Brett M. Hosking, S.-C. Mary Wang, Meredith Downes, Peter Koopman, and George E. O. Muscat
The VCAM-1 Gene That Encodes the Vascular Cell Adhesion Molecule Is a Target of the Sry-related High Mobility Group Box Gene, Sox18
J. Biol. Chem. 2004 279: 5314-5322. First Published on November 21, 2003; doi:10.1074/jbc.M308512200 [Abstract] [Full Text] [PDF]  

Di Jiang, Renny T. Franceschi, Heidi Boules, and Guozhi Xiao
Parathyroid Hormone Induction of the Osteocalcin Gene: REQUIREMENT FOR AN OSTEOBLAST-SPECIFIC ELEMENT 1 SEQUENCE IN THE PROMOTER AND INVOLVEMENT OF MULTIPLE SIGNALING PATHWAYS
J. Biol. Chem. 2004 279: 5329-5337. First Published on November 21, 2003; doi:10.1074/jbc.M311547200 [Abstract] [Full Text] [PDF]  

Anne Chapman-Smith, Jodi K. Lutwyche, and Murray L. Whitelaw
Contribution of the Per/Arnt/Sim (PAS) Domains to DNA Binding by the Basic Helix-Loop-Helix PAS Transcriptional Regulators
J. Biol. Chem. 2004 279: 5353-5362. First Published on November 24, 2003; doi:10.1074/jbc.M310041200 [Abstract] [Full Text] [PDF]  

Xiangdong Fang, Hemei Han, George Stamatoyannopoulos, and Qiliang Li
Developmentally Specific Role of the CCAAT Box in Regulation of Human {gamma}-Globin Gene Expression
J. Biol. Chem. 2004 279: 5444-5449. First Published on November 26, 2003; doi:10.1074/jbc.M306241200 [Abstract] [Full Text] [PDF]  

Dean Tantin, Maria Isabel Tussie-Luna, Ananda L. Roy, and Phillip A. Sharp
Regulation of Immunoglobulin Promoter Activity by TFII-I Class Transcription Factors
J. Biol. Chem. 2004 279: 5460-5469. First Published on November 26, 2003; doi:10.1074/jbc.M311177200 [Abstract] [Full Text] [PDF]  

Tsuyoshi Tahara, Jiying Sun, Katsuyuki Nakanishi, Masafumi Yamamoto, Hajime Mori, Takeshi Saito, Hiroyoshi Fujita, Kazuhiko Igarashi, and Shigeru Taketani
Heme Positively Regulates the Expression of {beta}-Globin at the Locus Control Region via the Transcriptional Factor Bach1 in Erythroid Cells
J. Biol. Chem. 2004 279: 5480-5487. First Published on December 1, 2003; doi:10.1074/jbc.M302733200 [Abstract] [Full Text] [PDF]  

Laurence Vaysse, Richard Harbottle, Brian Bigger, Anna Bergau, Oleg Tolmachov, and Charles Coutelle
Development of a Self-assembling Nuclear Targeting Vector System Based on the Tetracycline Repressor Protein
J. Biol. Chem. 2004 279: 5555-5564. First Published on November 7, 2003; doi:10.1074/jbc.M311894200 [Abstract] [Full Text] [PDF]  

Chieri Tomomori-Sato, Shigeo Sato, Tari J. Parmely, Charles A. S. Banks, Irina Sorokina, Laurence Florens, Boris Zybailov, Michael P. Washburn, Christopher S. Brower, Ronald C. Conaway, and Joan Weliky Conaway
A Mammalian Mediator Subunit that Shares Properties with Saccharomyces cerevisiae Mediator Subunit Cse2
J. Biol. Chem. 2004 279: 5846-5851. First Published on November 24, 2003; doi:10.1074/jbc.M312523200 [Abstract] [Full Text] [PDF] Supplemental DataSupplemental Data  

Vanisree Staniforth, Sheng-Yang Wang, Lie-Fen Shyur, and Ning-Sun Yang
Shikonins, Phytocompounds from Lithospermum erythrorhizon, Inhibit the Transcriptional Activation of Human Tumor Necrosis Factor {alpha} Promoter in Vivo
J. Biol. Chem. 2004 279: 5877-5885. First Published on November 25, 2003; doi:10.1074/jbc.M309185200 [Abstract] [Full Text] [PDF]  

Michael S. Bartlett, Michael Thomm, and E. Peter Geiduschek
Topography of the Euryarchaeal Transcription Initiation Complex
J. Biol. Chem. 2004 279: 5894-5903. First Published on November 13, 2003; doi:10.1074/jbc.M311429200 [Abstract] [Full Text] [PDF]  


RNA: Structure, Metabolism, and Catalysis:

Xue-hai Liang, Avivit Ochaion, Yu-xin Xu, Qing Liu, and Shulamit Michaeli
Small Nucleolar RNA Clusters in Trypanosomatid Leptomonas collosoma: GENOME ORGANIZATION, EXPRESSION STUDIES, AND THE POTENTIAL ROLE OF SEQUENCES PRESENT UPSTREAM FROM THE FIRST REPEATED CLUSTER
J. Biol. Chem. 2004 279: 5100-5109. First Published on November 30, 2003; doi:10.1074/jbc.M308264200 [Abstract] [Full Text] [PDF]  

Sheila Rydziel, Anne M. Delany, and Ernesto Canalis
AU-Rich Elements in the Collagenase 3 mRNA Mediate Stabilization of the Transcript by Cortisol in Osteoblasts
J. Biol. Chem. 2004 279: 5397-5404. First Published on November 25, 2003; doi:10.1074/jbc.M311984200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:

Mirco Fanelli, Anna Fantozzi, Pasquale De Luca, Sara Caprodossi, Shu-ichi Matsuzawa, Mitchell A. Lazar, Pier Giuseppe Pelicci, and Saverio Minucci
The Coiled-coil Domain Is the Structural Determinant for Mammalian Homologues of Drosophila Sina-mediated Degradation of Promyelocytic Leukemia Protein and Other Tripartite Motif Proteins by the Proteasome
J. Biol. Chem. 2004 279: 5374-5379. First Published on November 25, 2003; doi:10.1074/jbc.M306407200 [Abstract] [Full Text] [PDF]  

Sabrina Batonnet, Marie Pierre Leibovitch, Lionel Tintignac, and Serge Alexandre Leibovitch
Critical Role for Lysine 133 in the Nuclear Ubiquitin-mediated Degradation of MyoD
J. Biol. Chem. 2004 279: 5413-5420. First Published on November 30, 2003; doi:10.1074/jbc.M310315200 [Abstract] [Full Text] [PDF]  

Johanna Heske, Ulrich Heller, Konstanze F. Winklhofer, and Jörg Tatzelt
The C-terminal Globular Domain of the Prion Protein Is Necessary and Sufficient for Import into the Endoplasmic Reticulum
J. Biol. Chem. 2004 279: 5435-5443. First Published on November 26, 2003; doi:10.1074/jbc.M309570200 [Abstract] [Full Text] [PDF]  

Jens R. Bundgaard, Henrik Birkedal, and Jens F. Rehfeld
Progastrin Is Directed to the Regulated Secretory Pathway by Synergistically Acting Basic and Acidic Motifs
J. Biol. Chem. 2004 279: 5488-5493. First Published on December 1, 2003; doi:10.1074/jbc.M310547200 [Abstract] [Full Text] [PDF]  

Olga V. Leontieva and Jennifer D. Black
Identification of Two Distinct Pathways of Protein Kinase C{alpha} Down-regulation in Intestinal Epithelial Cells
J. Biol. Chem. 2004 279: 5788-5801. First Published on November 24, 2003; doi:10.1074/jbc.M308375200 [Abstract] [Full Text] [PDF]  

Vanesa Gottifredi, Kristine McKinney, Masha V. Poyurovsky, and Carol Prives
Decreased p21 Levels Are Required for Efficient Restart of DNA Synthesis after S Phase Block
J. Biol. Chem. 2004 279: 5802-5810. First Published on November 3, 2003; doi:10.1074/jbc.M310373200 [Abstract] [Full Text] [PDF]  

Alex E. Roher, Tyler A. Kokjohn, Chera Esh, Nicole Weiss, Jennifer Childress, Walter Kalback, Dean C. Luehrs, John Lopez, Daniel Brune, Yu-Min Kuo, Martin Farlow, Jill Murrell, Ruben Vidal, and Bernardino Ghetti
The Human Amyloid-{beta} Precursor Protein770 Mutation V717F Generates Peptides Longer Than Amyloid-{beta}-(40-42) and Flocculent Amyloid Aggregates
J. Biol. Chem. 2004 279: 5829-5836. First Published on November 26, 2003; doi:10.1074/jbc.M311380200 [Abstract] [Full Text] [PDF]  

Osnat Ben-Zeev and Mark H. Doolittle
Maturation of Hepatic Lipase: FORMATION OF FUNCTIONAL ENZYME IN THE ENDOPLASMIC RETICULUM IS THE RATE-LIMITING STEP IN ITS SECRETION
J. Biol. Chem. 2004 279: 6171-6181. First Published on November 20, 2003; doi:10.1074/jbc.M310051200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:

Peggy Baudouin-Cornu, Katja Schuerer, Philippe Marlière, and Dominique Thomas
Intimate Evolution of Proteins: PROTEOME ATOMIC CONTENT CORRELATES WITH GENOME BASE COMPOSITION
J. Biol. Chem. 2004 279: 5421-5428. First Published on November 29, 2003; doi:10.1074/jbc.M306415200 [Abstract] [Full Text] [PDF]  

Li Gan, Shiming Ye, Alan Chu, Kristin Anton, Saili Yi, Valerie A. Vincent, David von Schack, Daniel Chin, Joseph Murray, Scott Lohr, Laszlo Patthy, Mirella Gonzalez-Zulueta, Karoly Nikolich, and Roman Urfer
Identification of Cathepsin B as a Mediator of Neuronal Death Induced by A{beta}-activated Microglial Cells Using a Functional Genomics Approach
J. Biol. Chem. 2004 279: 5565-5572. First Published on November 10, 2003; doi:10.1074/jbc.M306183200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Dominik Rünzler, Carina Huber, Dieter Moll, Gottfried Köhler, and Margit Sára
Biophysical Characterization of the Entire Bacterial Surface Layer Protein SbsB and Its Two Distinct Functional Domains
J. Biol. Chem. 2004 279: 5207-5215. First Published on November 17, 2003; doi:10.1074/jbc.M308819200 [Abstract] [Full Text] [PDF]  

Rosemary Bass, Lloyd W. Ruddock, Peter Klappa, and Robert B. Freedman
A Major Fraction of Endoplasmic Reticulum-located Glutathione Is Present as Mixed Disulfides with Protein
J. Biol. Chem. 2004 279: 5257-5262. First Published on November 20, 2003; doi:10.1074/jbc.M304951200 [Abstract] [Full Text] [PDF]  

Yraima Cordeiro, Luís Maurício T. R. Lima, Mariana P. B. Gomes, Débora Foguel, and Jerson L. Silva
Modulation of Prion Protein Oligomerization, Aggregation, and {beta}-sheet Conversion by 4,4'-Dianilino-1,1'-binaphthyl-5,5'-sulfonate (bis-ANS)
J. Biol. Chem. 2004 279: 5346-5352. First Published on November 21, 2003; doi:10.1074/jbc.M312262200 [Abstract] [Full Text] [PDF]  

André Schiefner, Jason Breed, Linda Bösser, Susanne Kneip, Jutta Gade, Gudrun Holtmann, Kay Diederichs, Wolfram Welte, and Erhard Bremer
Cation-{pi} Interactions as Determinants for Binding of the Compatible Solutes Glycine Betaine and Proline Betaine by the Periplasmic Ligand-binding Protein ProX from Escherichia coli
J. Biol. Chem. 2004 279: 5588-5596. First Published on November 11, 2003; doi:10.1074/jbc.M309771200 [Abstract] [Full Text] [PDF]  

Ute Krengel, Lise-Lotte Olsson, Carlos Martínez, Ariel Talavera, Gertrudis Rojas, Elin Mier, Jonas Ångström, and Ernesto Moreno
Structure and Molecular Interactions of a Unique Antitumor Antibody Specific for N-Glycolyl GM3
J. Biol. Chem. 2004 279: 5597-5603. First Published on November 19, 2003; doi:10.1074/jbc.M311693200 [Abstract] [Full Text] [PDF]  

Jessica L. Blazyk and Stephen J. Lippard
Domain Engineering of the Reductase Component of Soluble Methane Monooxygenase from Methylococcus capsulatus (Bath)
J. Biol. Chem. 2004 279: 5630-5640. First Published on November 12, 2003; doi:10.1074/jbc.M308940200 [Abstract] [Full Text] [PDF]  

Elizabeth Hong-Geller, Margit Möllhoff, Patrick R. Shiflett, and Goutam Gupta
Design of Chimeric Receptor Mimics with Different TcRV{beta} Isoforms: TYPE-SPECIFIC INHIBITION OF SUPERANTIGEN PATHOGENESIS
J. Biol. Chem. 2004 279: 5676-5684. First Published on November 6, 2003; doi:10.1074/jbc.M309388200 [Abstract] [Full Text] [PDF]  

Anders Olofsson, Johannes H. Ippel, Sybren S. Wijmenga, Erik Lundgren, and Anders Öhman
Probing Solvent Accessibility of Transthyretin Amyloid by Solution NMR Spectroscopy
J. Biol. Chem. 2004 279: 5699-5707. First Published on November 6, 2003; doi:10.1074/jbc.M310605200 [Abstract] [Full Text] [PDF]  

Ian R. Bates, Jimmy B. Feix, Joan M. Boggs, and George Harauz
An Immunodominant Epitope of Myelin Basic Protein Is an Amphipathic {alpha}-Helix
J. Biol. Chem. 2004 279: 5757-5764. First Published on November 20, 2003; doi:10.1074/jbc.M311504200 [Abstract] [Full Text] [PDF]  

Vitaliy Y. Gorbatyuk, Cheng-Kun Tsai, Chi-Fon Chang, and Tai-huang Huang
Effect of N-terminal and Met23 Mutations on the Structure and Dynamics of Onconase
J. Biol. Chem. 2004 279: 5772-5780. First Published on November 26, 2003; doi:10.1074/jbc.M311233200 [Abstract] [Full Text] [PDF] Supplemental Data  

Tadayuki Uno, Daisuke Ryu, Hiroko Tsutsumi, Yoshikazu Tomisugi, Yoshinobu Ishikawa, Anthony J. Wilkinson, Hideaki Sato, and Takashi Hayashi
Residues in the Distal Heme Pocket of Neuroglobin: IMPLICATIONS FOR THE MULTIPLE LIGAND BINDING STEPS
J. Biol. Chem. 2004 279: 5886-5893. First Published on November 27, 2003; doi:10.1074/jbc.M311748200 [Abstract] [Full Text] [PDF]  

Akira Hayakawa, Susan J. Hayes, Deirdre C. Lawe, Eathiraj Sudharshan, Richard Tuft, Kevin Fogarty, David Lambright, and Silvia Corvera
Structural Basis for Endosomal Targeting by FYVE Domains
J. Biol. Chem. 2004 279: 5958-5966. First Published on October 31, 2003; doi:10.1074/jbc.M310503200 [Abstract] [Full Text] [PDF]  

Xiang Yang Liu and Ning Du
Zero-sized Effect of Nano-particles and Inverse Homogeneous Nucleation: PRINCIPLES OF FREEZING AND ANTIFREEZE
J. Biol. Chem. 2004 279: 6124-6131. First Published on November 5, 2003; doi:10.1074/jbc.M310487200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Yasuhisa Sakata, Kazuhiko Arima, Toshiro Takai, Wataru Sakurai, Kiyonari Masumoto, Noriko Yuyama, Yoshinori Suminami, Fumio Kishi, Tetsuji Yamashita, Takeshi Kato, Hideoki Ogawa, Kazuma Fujimoto, Yo Matsuo, Yuji Sugita, and Kenji Izuhara
The Squamous Cell Carcinoma Antigen 2 Inhibits the Cysteine Proteinase Activity of a Major Mite Allergen, Der p 1
J. Biol. Chem. 2004 279: 5081-5087. First Published on November 20, 2003; doi:10.1074/jbc.M311585200 [Abstract] [Full Text] [PDF]  

Yasushi Hanakawa, Norman M. Schechter, Chenyan Lin, Koji Nishifuji, Masayuki Amagai, and John R. Stanley
Enzymatic and Molecular Characteristics of the Efficiency and Specificity of Exfoliative Toxin Cleavage of Desmoglein 1
J. Biol. Chem. 2004 279: 5268-5277. First Published on November 20, 2003; doi:10.1074/jbc.M311087200 [Abstract] [Full Text] [PDF]  

Zhenqiang Li, Yoshiyuki Yasuda, Weijie Li, Matthew Bogyo, Norman Katz, Ronald E. Gordon, Gregg B. Fields, and Dieter Brömme
Regulation of Collagenase Activities of Human Cathepsins by Glycosaminoglycans
J. Biol. Chem. 2004 279: 5470-5479. First Published on November 26, 2003; doi:10.1074/jbc.M310349200 [Abstract] [Full Text] [PDF]  

Matthew E. C. Caines, Jonathan M. Elkins, Kirsty S. Hewitson, and Christopher J. Schofield
Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
J. Biol. Chem. 2004 279: 5685-5692. First Published on November 17, 2003; doi:10.1074/jbc.M310803200 [Abstract] [Full Text] [PDF]  

Amy S. Hearn, Li Fan, James R. Lepock, James P. Luba, William B. Greenleaf, Diane E. Cabelli, John A. Tainer, Harry S. Nick, and David N. Silverman
Amino Acid Substitution at the Dimeric Interface of Human Manganese Superoxide Dismutase
J. Biol. Chem. 2004 279: 5861-5866. First Published on November 24, 2003; doi:10.1074/jbc.M311310200 [Abstract] [Full Text] [PDF]  

Tudor Moldoveanu, Zongchao Jia, and Peter L. Davies
Calpain Activation by Cooperative Ca2+ Binding at Two Non-EF-hand Sites
J. Biol. Chem. 2004 279: 6106-6114. First Published on October 27, 2003; doi:10.1074/jbc.M310460200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Antonella Cartoni, Pierantonio Menna, Emanuela Salvatorelli, Daniela Braghiroli, Rossella Giampietro, Fabio Animati, Andrea Urbani, Piero Del Boccio, and Giorgio Minotti
Oxidative Degradation of Cardiotoxic Anticancer Anthracyclines to Phthalic Acids: NOVEL FUNCTION FOR FERRYLMYOGLOBIN
J. Biol. Chem. 2004 279: 5088-5099. First Published on November 21, 2003; doi:10.1074/jbc.M306568200 [Abstract] [Full Text] [PDF]  

Alison M. Snyder, Bruce M. Clark, Bruno Robert, Alexander V. Ruban, and Ralph A. Bungard
Carotenoid Specificity of Light-harvesting Complex II Binding Sites: OCCURRENCE OF 9-CIS-VIOLAXANTHIN IN THE NEOXANTHIN-BINDING SITE IN THE PARASITIC ANGIOSPERM CUSCUTA REFLEXA
J. Biol. Chem. 2004 279: 5162-5168. First Published on November 10, 2003; doi:10.1074/jbc.M309676200 [Abstract] [Full Text] [PDF]  

Graham H. Coombs, Gareth D. Westrop, Pavel Suchan, Gabriela Puzova, Robert P. Hirt, T. Martin Embley, Jeremy C. Mottram, and Sylke Müller
The Amitochondriate Eukaryote Trichomonas vaginalis Contains a Divergent Thioredoxin-linked Peroxiredoxin Antioxidant System
J. Biol. Chem. 2004 279: 5249-5256. First Published on November 20, 2003; doi:10.1074/jbc.M304359200 [Abstract] [Full Text] [PDF]  

Hong-Liang Wang, Bradley L. Postier, and Robert L. Burnap
Alterations in Global Patterns of Gene Expression in Synechocystis sp. PCC 6803 in Response to Inorganic Carbon Limitation and the Inactivation of ndhR, a LysR Family Regulator
J. Biol. Chem. 2004 279: 5739-5751. First Published on November 11, 2003; doi:10.1074/jbc.M311336200 [Abstract] [Full Text] [PDF] Supplemental Data  


Glycobiology and Extracellular Matrices:

Kerstin Künneken, Gottfried Pohlentz, Alletta Schmidt-Hederich, Uwe Odenthal, Neil Smyth, Jasna Peter-Katalinic, Peter Bruckner, and Johannes A. Eble
Recombinant Human Laminin-5 Domains: EFFECTS OF HETEROTRIMERIZATION, PROTEOLYTIC PROCESSING, AND N-GLYCOSYLATION ON {alpha}3{beta}1 INTEGRIN BINDING
J. Biol. Chem. 2004 279: 5184-5193. First Published on November 11, 2003; doi:10.1074/jbc.M310424200 [Abstract] [Full Text] [PDF]  

Adriane R. Todeschini, Wagner B. Dias, Murielle F. Girard, Jean-Michel Wieruszeski, Lucia Mendonça-Previato, and Jose O. Previato
Enzymatically Inactive trans-Sialidase from Trypanosoma cruzi Binds Sialyl and {beta}-Galactopyranosyl Residues in a Sequential Ordered Mechanism
J. Biol. Chem. 2004 279: 5323-5328. First Published on November 21, 2003; doi:10.1074/jbc.M310663200 [Abstract] [Full Text] [PDF]  

Beth L. Viviano, Stephenie Paine-Saunders, Nijole Gasiunas, John Gallagher, and Scott Saunders
Domain-specific Modification of Heparan Sulfate by Qsulf1 Modulates the Binding of the Bone Morphogenetic Protein Antagonist Noggin
J. Biol. Chem. 2004 279: 5604-5611. First Published on November 25, 2003; doi:10.1074/jbc.M310691200 [Abstract] [Full Text] [PDF]  

Ge Wei, Xiaomei Bai, and Jeffrey D. Esko
Temperature-sensitive Glycosaminoglycan Biosynthesis in a Chinese Hamster Ovary Cell Mutant Containing a Point Mutation in Glucuronyltransferase I
J. Biol. Chem. 2004 279: 5693-5698. First Published on November 17, 2003; doi:10.1074/jbc.M311621200 [Abstract] [Full Text] [PDF]  

Shigetoshi Eda, Masahiro Yamanaka, and Masatoshi Beppu
Carbohydrate-mediated Phagocytic Recognition of Early Apoptotic Cells Undergoing Transient Capping of CD43 Glycoprotein
J. Biol. Chem. 2004 279: 5967-5974. First Published on November 12, 2003; doi:10.1074/jbc.M310805200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Yasuo Okamoto, Jun Morishita, Kazuhito Tsuboi, Takeharu Tonai, and Natsuo Ueda
Molecular Characterization of a Phospholipase D Generating Anandamide and Its Congeners
J. Biol. Chem. 2004 279: 5298-5305. First Published on November 21, 2003; doi:10.1074/jbc.M306642200 [Abstract] [Full Text] [PDF]  

Gil-Soo Han, Celeste N. Johnston, and George M. Carman
Vacuole Membrane Topography of the DPP1-encoded Diacylglycerol Pyrophosphate Phosphatase Catalytic Site from Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 5338-5345. First Published on November 20, 2003; doi:10.1074/jbc.M311779200 [Abstract] [Full Text] [PDF]  

Rolf Westerberg, Petr Tvrdik, Anne-Birgitte Undén, Jan-Erik Månsson, Lars Norlén, Andreas Jakobsson, Walter H. Holleran, Peter M. Elias, Abolfazl Asadi, Per Flodby, Rune Toftgård, Mario R. Capecchi, and Anders Jacobsson
Role for ELOVL3 and Fatty Acid Chain Length in Development of Hair and Skin Function
J. Biol. Chem. 2004 279: 5621-5629. First Published on October 27, 2003; doi:10.1074/jbc.M310529200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:

Andrew B. Maxfield, Daren N. Heaton, and Dennis R. Winge
Cox17 Is Functional When Tethered to the Mitochondrial Inner Membrane
J. Biol. Chem. 2004 279: 5072-5080. First Published on November 13, 2003; doi:10.1074/jbc.M311772200 [Abstract] [Full Text] [PDF]  

Elena Taverna, Elena Saba, Joanna Rowe, Maura Francolini, Francesco Clementi, and Patrizia Rosa
Role of Lipid Microdomains in P/Q-type Calcium Channel (Cav2.1) Clustering and Function in Presynaptic Membranes
J. Biol. Chem. 2004 279: 5127-5134. First Published on December 2, 2003; doi:10.1074/jbc.M308798200 [Abstract] [Full Text] [PDF]  

Gregory Tombline, Lori Bartholomew, Khursheed Gimi, Grace A. Tyndall, and Alan E. Senior
Synergy between Conserved ABC Signature Ser Residues in P-glycoprotein Catalysis
J. Biol. Chem. 2004 279: 5363-5373. First Published on November 24, 2003; doi:10.1074/jbc.M311964200 [Abstract] [Full Text] [PDF]  

Chris Ryan, David L. Stokes, Minggui Chen, Zhimin Zhang, and Peter M. D. Hardwicke
Effect of Orthophosphate, Nucleotide Analogues, ADP, and Phosphorylation on the Cytoplasmic Domains of Ca2+-ATPase from Scallop Sarcoplasmic Reticulum
J. Biol. Chem. 2004 279: 5380-5386. First Published on November 25, 2003; doi:10.1074/jbc.M310085200 [Abstract] [Full Text] [PDF]  

Wolfgang Biasio, Tina Chang, C. Joy McIntosh, and Fiona J. McDonald
Identification of Murr1 as a Regulator of the Human {delta} Epithelial Sodium Channel
J. Biol. Chem. 2004 279: 5429-5434. First Published on November 27, 2003; doi:10.1074/jbc.M311155200 [Abstract] [Full Text] [PDF]  

Noriyuki Hatano, Susumu Ohya, Katsuhiko Muraki, Robert B. Clark, Wayne R. Giles, and Yuji Imaizumi
Two Arginines in the Cytoplasmic C-terminal Domain Are Essential for Voltage-dependent Regulation of A-type K+ Current in the Kv4 Channel Subfamily
J. Biol. Chem. 2004 279: 5450-5459. First Published on November 26, 2003; doi:10.1074/jbc.M302034200 [Abstract] [Full Text] [PDF]  

Peter M. Haggie, Bruce A. Stanton, and A. S. Verkman
Increased Diffusional Mobility of CFTR at the Plasma Membrane after Deletion of Its C-terminal PDZ Binding Motif
J. Biol. Chem. 2004 279: 5494-5500. First Published on December 1, 2003; doi:10.1074/jbc.M312445200 [Abstract] [Full Text] [PDF]  

Nianhang Chen, Judy Rickey, Janet L. Berfield, and Maarten E. A. Reith
Aspartate 345 of the Dopamine Transporter Is Critical for Conformational Changes in Substrate Translocation and Cocaine Binding
J. Biol. Chem. 2004 279: 5508-5519. First Published on December 2, 2003; doi:10.1074/jbc.M306294200 [Abstract] [Full Text] [PDF]  

Vinciane Grimard, Canhui Li, Mohabir Ramjeesingh, Christine E. Bear, Erik Goormaghtigh, and Jean-Marie Ruysschaert
Phosphorylation-induced Conformational Changes of Cystic Fibrosis Transmembrane Conductance Regulator Monitored by Attenuated Total Reflection-Fourier Transform IR Spectroscopy and Fluorescence Spectroscopy
J. Biol. Chem. 2004 279: 5528-5536. First Published on December 2, 2003; doi:10.1074/jbc.M311014200 [Abstract] [Full Text] [PDF]  

Maria-Manuel Sampaio, Fabienne Chevance, Renate Dippel, Tanja Eppler, Anja Schlegel, Winfried Boos, Ying-Jie Lu, and Charles O. Rock
Phosphotransferase-mediated Transport of the Osmolyte 2-O-{alpha}-Mannosyl-D-glycerate in Escherichia coli Occurs by the Product of the mngA (hrsA) Gene and Is Regulated by the mngR (farR) Gene Product Acting as Repressor
J. Biol. Chem. 2004 279: 5537-5548. First Published on November 25, 2003; doi:10.1074/jbc.M310980200 [Abstract] [Full Text] [PDF]  

Leo A. Kim, Johannes Furst, Margaret H. Butler, Shuhua Xu, Nikolaus Grigorieff, and Steve A. N. Goldstein
Ito Channels Are Octomeric Complexes with Four Subunits of Each Kv4.2 and K+ Channel-interacting Protein 2
J. Biol. Chem. 2004 279: 5549-5554. First Published on November 17, 2003; doi:10.1074/jbc.M311332200 [Abstract] [Full Text] [PDF]  

Édith Gagnon, Marc J. Bergeron, Geneviève M. Brunet, Nikolas D. Daigle, Charles F. Simard, and Paul Isenring
Molecular Mechanisms of Cl- Transport by the Renal Na+-K+-Cl- Cotransporter: IDENTIFICATION OF AN INTRACELLULAR LOCUS THAT MAY FORM PART OF A HIGH AFFINITY Cl--BINDING SITE
J. Biol. Chem. 2004 279: 5648-5654. First Published on November 27, 2003; doi:10.1074/jbc.M311218200 [Abstract] [Full Text] [PDF]  

John W. J. Hinrichs, Karin Klappe, Ina Hummel, and Jan W. Kok
ATP-binding Cassette Transporters Are Enriched in Non-caveolar Detergent-insoluble Glycosphingolipid-enriched Membrane Domains (DIGs) in Human Multidrug-resistant Cancer Cells
J. Biol. Chem. 2004 279: 5734-5738. First Published on November 19, 2003; doi:10.1074/jbc.M306857200 [Abstract] [Full Text] [PDF]  

Xinjiang Cai and Jonathan Lytton
Molecular Cloning of a Sixth Member of the K+-dependent Na+/Ca2+ Exchanger Gene Family, NCKX6
J. Biol. Chem. 2004 279: 5867-5876. First Published on November 18, 2003; doi:10.1074/jbc.M310908200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Thiruvengadam Arumugam, Diane M. Simeone, Ann Marie Schmidt, and Craig D. Logsdon
S100P Stimulates Cell Proliferation and Survival via Receptor for Activated Glycation End Products (RAGE)
J. Biol. Chem. 2004 279: 5059-5065. First Published on November 14, 2003; doi:10.1074/jbc.M310124200 [Abstract] [Full Text] [PDF]  

Johan Bonnevier, Reinhard Fässler, Andrew P. Somlyo, Avril V. Somlyo, and Anders Arner
Modulation of Ca2+ Sensitivity by Cyclic Nucleotides in Smooth Muscle from Protein Kinase G-deficient Mice
J. Biol. Chem. 2004 279: 5146-5151. First Published on November 10, 2003; doi:10.1074/jbc.M306532200 [Abstract] [Full Text] [PDF]  

Remko A. Bakker, Paola Casarosa, Henk Timmerman, Martine J. Smit, and Rob Leurs
Constitutively active Gq/11-coupled Receptors Enable Signaling by Co-expressed Gi/o-coupled Receptors
J. Biol. Chem. 2004 279: 5152-5161. First Published on November 10, 2003; doi:10.1074/jbc.M309200200 [Abstract] [Full Text] [PDF]  

Ji-Sook Hahn and Dennis J. Thiele
Activation of the Saccharomyces cerevisiae Heat Shock Transcription Factor Under Glucose Starvation Conditions by Snf1 Protein Kinase
J. Biol. Chem. 2004 279: 5169-5176. First Published on November 10, 2003; doi:10.1074/jbc.M311005200 [Abstract] [Full Text] [PDF]  

Fiona M. Townsley, Barry Thompson, and Mariann Bienz
Pygopus Residues Required for its Binding to Legless Are Critical for Transcription and Development
J. Biol. Chem. 2004 279: 5177-5183. First Published on November 11, 2003; doi:10.1074/jbc.M309722200 [Abstract] [Full Text] [PDF]  

Véronique Neaud, Jennifer Gillibert Duplantier, Claire Mazzocco, Walter Kisiel, and Jean Rosenbaum
Thrombin Up-regulates Tissue Factor Pathway Inhibitor-2 Synthesis through a Cyclooxygenase-2-dependent, Epidermal Growth Factor Receptor-independent Mechanism
J. Biol. Chem. 2004 279: 5200-5206. First Published on November 17, 2003; doi:10.1074/jbc.M306679200 [Abstract] [Full Text] [PDF]  

Nevin M. Perera, Robert H. Michell, and Stephen K. Dove
Hypo-osmotic Stress Activates Plc1p-dependent Phosphatidylinositol 4,5-Bisphosphate Hydrolysis and Inositol Hexakisphosphate Accumulation in Yeast
J. Biol. Chem. 2004 279: 5216-5226. First Published on November 18, 2003; doi:10.1074/jbc.M305068200 [Abstract] [Full Text] [PDF]  

Christian Kollewe, Anne-Christin Mackensen, Detlef Neumann, Johannes Knop, Ping Cao, Shyun Li, Holger Wesche, and Michael U. Martin
Sequential Autophosphorylation Steps in the Interleukin-1 Receptor-associated Kinase-1 Regulate its Availability as an Adapter in Interleukin-1 Signaling
J. Biol. Chem. 2004 279: 5227-5236. First Published on November 18, 2003; doi:10.1074/jbc.M309251200 [Abstract] [Full Text] [PDF]  

Xue Wang, Yushen Zhou, Hong Pyo Kim, Ruiping Song, Reza Zarnegar, Stefan W. Ryter, and Augustine M. K. Choi
Hepatocyte Growth Factor Protects against Hypoxia/Reoxygenation-induced Apoptosis in Endothelial Cells
J. Biol. Chem. 2004 279: 5237-5243. First Published on November 18, 2003; doi:10.1074/jbc.M309271200 [Abstract] [Full Text] [PDF]  

Nicola Wiechens, Karolin Heinle, Ludwig Englmeier, Anne Schohl, and François Fagotto
Nucleo-cytoplasmic Shuttling of Axin, a Negative Regulator of the Wnt-{beta}-Catenin Pathway
J. Biol. Chem. 2004 279: 5263-5267. First Published on November 20, 2003; doi:10.1074/jbc.M307253200 [Abstract] [Full Text] [PDF]  

Han C. Dan, Mei Sun, Satoshi Kaneko, Richard I. Feldman, Santo V. Nicosia, Hong-Gang Wang, Benjamin K. Tsang, and Jin Q. Cheng
Akt Phosphorylation and Stabilization of X-linked Inhibitor of Apoptosis Protein (XIAP)
J. Biol. Chem. 2004 279: 5405-5412. First Published on November 25, 2003; doi:10.1074/jbc.M312044200 [Abstract] [Full Text] [PDF]  

Oxana M. Tsygankova, Elena Feshchenko, Peter S. Klein, and Judy L. Meinkoth
Thyroid-stimulating Hormone/cAMP and Glycogen Synthase Kinase 3{beta} Elicit Opposing Effects on Rap1GAP Stability
J. Biol. Chem. 2004 279: 5501-5507. First Published on December 2, 2003; doi:10.1074/jbc.M305824200 [Abstract] [Full Text] [PDF]  

James J. Moon, Eric D. Rubio, Anthony Martino, Anton Krumm, and Brad H. Nelson
A Permissive Role for Phosphatidylinositol 3-Kinase in the Stat5- mediated Expression of Cyclin D2 by the Interleukin-2 Receptor
J. Biol. Chem. 2004 279: 5520-5527. First Published on December 2, 2003; doi:10.1074/jbc.M308998200 [Abstract] [Full Text] [PDF]  

Anthony C. Cruz, Brendon T. Frank, Samuel T. Edwards, Paul F. Dazin, Jacques J. Peschon, and Kenneth C. Fang
Tumor Necrosis Factor-{alpha}-converting Enzyme Controls Surface Expression of c-Kit and Survival of Embryonic Stem Cell-derived Mast Cells
J. Biol. Chem. 2004 279: 5612-5620. First Published on November 18, 2003; doi:10.1074/jbc.M312323200 [Abstract] [Full Text] [PDF]  

Alexander Schwarz, Eberhard Tutsch, Bianca Ludwig, Eva C. Schwarz, Andreas Stallmach, and Markus Hoth
Ca2+ Signaling in Identified T-lymphocytes from Human Intestinal Mucosa: RELATION TO HYPOREACTIVITY, PROLIFERATION, AND INFLAMMATORY BOWEL DISEASE
J. Biol. Chem. 2004 279: 5641-5647. First Published on October 29, 2003; doi:10.1074/jbc.M309317200 [Abstract] [Full Text] [PDF]  

Eun-Young Ahn, Ssang-Taek Lim, William J. Cook, and Jay M. McDonald
Calmodulin Binding to the Fas Death Domain: REGULATION BY FAS ACTIVATION
J. Biol. Chem. 2004 279: 5661-5666. First Published on October 31, 2003; doi:10.1074/jbc.M311040200 [Abstract] [Full Text] [PDF]  

Kanneganti G. K. Murthy, Amitabha Deb, Sunali Goonesekera, Csaba Szabó, and Andrew L. Salzman
Identification of Conserved Domains in Salmonella muenchen Flagellin That Are Essential for Its Ability to Activate TLR5 and to Induce an Inflammatory Response in Vitro
J. Biol. Chem. 2004 279: 5667-5675. First Published on November 21, 2003; doi:10.1074/jbc.M307759200 [Abstract] [Full Text] [PDF]  

Ronit Heinrich, Erella Livne, Offer Ben-Izhak, and Ami Aronheim
The c-Jun Dimerization Protein 2 Inhibits Cell Transformation and Acts as a Tumor Suppressor Gene
J. Biol. Chem. 2004 279: 5708-5715. First Published on November 19, 2003; doi:10.1074/jbc.M307608200 [Abstract] [Full Text] [PDF]  

George Boguslawski, Patrick W. McGlynn, Kevin A. Harvey, and A. Thomas Kovala
SU1498, an Inhibitor of Vascular Endothelial Growth Factor Receptor 2, Causes Accumulation of Phosphorylated ERK Kinases and Inhibits Their Activity in Vivo and in Vitro
J. Biol. Chem. 2004 279: 5716-5724. First Published on November 18, 2003; doi:10.1074/jbc.M308625200 [Abstract] [Full Text] [PDF]  

Sergio Roman-Roman, De-Li Shi, Véronique Stiot, Eric Haÿ, Béatrice Vayssière, Teresa Garcia, Roland Baron, and Georges Rawadi
Murine Frizzled-1 Behaves as an Antagonist of the Canonical Wnt/{beta}-Catenin Signaling
J. Biol. Chem. 2004 279: 5725-5733. First Published on November 24, 2003; doi:10.1074/jbc.M309233200 [Abstract] [Full Text] [PDF]  

Christopher W. Ward, Wei Feng, Jiangchen Tu, Isaac N. Pessah, Paul K. Worley, and Martin F. Schneider
Homer Protein Increases Activation of Ca2+ Sparks in Permeabilized Skeletal Muscle
J. Biol. Chem. 2004 279: 5781-5787. First Published on December 3, 2003; doi:10.1074/jbc.M311422200 [Abstract] [Full Text] [PDF]  

Seema Gupta, Ramesh Natarajan, Shawn G. Payne, Elaine J. Studer, Sarah Spiegel, Paul Dent, and Phillip B. Hylemon
Deoxycholic Acid Activates the c-Jun N-terminal Kinase Pathway via FAS Receptor Activation in Primary Hepatocytes: ROLE OF ACIDIC SPHINGOMYELINASE-MEDIATED CERAMIDE GENERATION IN FAS RECEPTOR ACTIVATION
J. Biol. Chem. 2004 279: 5821-5828. First Published on December 2, 2003; doi:10.1074/jbc.M310979200 [Abstract] [Full Text] [PDF]  

Young-Mi Go, Jerry J. Gipp, R. Timothy Mulcahy, and Dean P. Jones
H2O2-dependent Activation of GCLC-ARE4 Reporter Occurs by Mitogen-activated Protein Kinase Pathways without Oxidation of Cellular Glutathione or Thioredoxin-1
J. Biol. Chem. 2004 279: 5837-5845. First Published on November 24, 2003; doi:10.1074/jbc.M307547200 [Abstract] [Full Text] [PDF]  

Eun-Mi Hur, Yong-Soo Park, Byoung Dae Lee, Il Ho Jang, Hyeon Soo Kim, Tae-Don Kim, Pann-Ghill Suh, Sung Ho Ryu, and Kyong-Tai Kim
Sensitization of Epidermal Growth Factor-induced Signaling by Bradykinin Is Mediated by c-Src: IMPLICATIONS FOR A ROLE OF LIPID MICRODOMAINS
J. Biol. Chem. 2004 279: 5852-5860. First Published on November 20, 2003; doi:10.1074/jbc.M311687200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ya-Xiong Tao, Nathan B. Johnson, and Deborah L. Segaloff
Constitutive and Agonist-dependent Self-association of the Cell Surface Human Lutropin Receptor
J. Biol. Chem. 2004 279: 5904-5914. First Published on October 31, 2003; doi:10.1074/jbc.M311162200 [Abstract] [Full Text] [PDF]  

Frank Altznauer, Sébastien Conus, Andrea Cavalli, Gerd Folkers, and Hans-Uwe Simon
Calpain-1 Regulates Bax and Subsequent Smac-dependent Caspase-3 Activation in Neutrophil Apoptosis
J. Biol. Chem. 2004 279: 5947-5957. First Published on November 11, 2003; doi:10.1074/jbc.M308576200 [Abstract] [Full Text] [PDF]  

Hidetada Matsuoka, Shigeyuki Nada, and Masato Okada
Mechanism of Csk-mediated Down-regulation of Src Family Tyrosine Kinases in Epidermal Growth Factor Signaling
J. Biol. Chem. 2004 279: 5975-5983. First Published on November 12, 2003; doi:10.1074/jbc.M311278200 [Abstract] [Full Text] [PDF] Supplemental Data  

Victor M. Brown, Eugene Y. Krynetski, Natalia F. Krynetskaia, Dara Grieger, Suraj T. Mukatira, Kuruganti G. Murti, Clive A. Slaughter, Hee-Won Park, and William E. Evans
A Novel CRM1-mediated Nuclear Export Signal Governs Nuclear Accumulation of Glyceraldehyde-3-phosphate Dehydrogenase following Genotoxic Stress
J. Biol. Chem. 2004 279: 5984-5992. First Published on November 14, 2003; doi:10.1074/jbc.M307071200 [Abstract] [Full Text] [PDF]  

John H. Evans and Christina C. Leslie
The Cytosolic Phospholipase A2 Catalytic Domain Modulates Association and Residence Time at Golgi Membranes
J. Biol. Chem. 2004 279: 6005-6016. First Published on November 17, 2003; doi:10.1074/jbc.M311246200 [Abstract] [Full Text] [PDF] Supplemental Data  

Masahiko Watabe, Keiichi Hishikawa, Atsushi Takayanagi, Nobuyoshi Shimizu, and Toshio Nakaki
Caffeic Acid Phenethyl Ester Induces Apoptosis by Inhibition of NF{kappa}B and Activation of Fas in Human Breast Cancer MCF-7 Cells
J. Biol. Chem. 2004 279: 6017-6026. First Published on November 18, 2003; doi:10.1074/jbc.M306040200 [Abstract] [Full Text] [PDF]  

Yulia Y. Tyurina, F. Behice Serinkan, Vladimir A. Tyurin, Vidisha Kini, Jack C. Yalowich, Alan J. Schroit, Bengt Fadeel, and Valerian E. Kagan
Lipid Antioxidant, Etoposide, Inhibits Phosphatidylserine Externalization and Macrophage Clearance of Apoptotic Cells by Preventing Phosphatidylserine Oxidation
J. Biol. Chem. 2004 279: 6056-6064. First Published on November 20, 2003; doi:10.1074/jbc.M309929200 [Abstract] [Full Text] [PDF]  

Alok C. Bharti, Yasunari Takada, Shishir Shishodia, and Bharat B. Aggarwal
Evidence That Receptor Activator of Nuclear Factor (NF)-{kappa}B Ligand Can Suppress Cell Proliferation and Induce Apoptosis through Activation of a NF-{kappa}B-independent and TRAF6-dependent Mechanism
J. Biol. Chem. 2004 279: 6065-6076. First Published on November 25, 2003; doi:10.1074/jbc.M308062200 [Abstract] [Full Text] [PDF]  

Yue Qiu, Haruo Ogawa, Masaru Miyagi, and Kunio S. Misono
Constitutive Activation and Uncoupling of the Atrial Natriuretic Peptide Receptor by Mutations at the Dimer Interface: ROLE OF THE DIMER STRUCTURE IN SIGNALING
J. Biol. Chem. 2004 279: 6115-6123. First Published on November 4, 2003; doi:10.1074/jbc.M310225200 [Abstract] [Full Text] [PDF] Suppplemental Data  

M. José Pérez-García, Valentín Ceña, Yolanda de Pablo, Marta Llovera, Joan X. Comella, and Rosa M. Soler
Glial Cell Line-derived Neurotrophic Factor Increases Intracellular Calcium Concentration: ROLE OF CALCIUM/CALMODULIN IN THE ACTIVATION OF THE PHOSPHATIDYLINOSITOL 3-KINASE PATHWAY
J. Biol. Chem. 2004 279: 6132-6142. First Published on November 20, 2003; doi:10.1074/jbc.M308367200 [Abstract] [Full Text] [PDF]  

Kamala P. Sundararaj, Rachel E. Wood, Suriyan Ponnusamy, Arelis M. Salas, Zdzislaw Szulc, Alicia Bielawska, Lina M. Obeid, Yusuf A. Hannun, and Besim Ogretmen
Rapid Shortening of Telomere Length in Response to Ceramide Involves the Inhibition of Telomere Binding Activity of Nuclear Glyceraldehyde-3-phosphate Dehydrogenase
J. Biol. Chem. 2004 279: 6152-6162. First Published on November 20, 2003; doi:10.1074/jbc.M310549200 [Abstract] [Full Text] [PDF]  

Ana Barac, John Basile, José Vázquez-Prado, Yuan Gao, Yi Zheng, and J. Silvio Gutkind
Direct Interaction of p21-Activated Kinase 4 with PDZ-RhoGEF, a G Protein-linked Rho Guanine Exchange Factor
J. Biol. Chem. 2004 279: 6182-6189. First Published on November 18, 2003; doi:10.1074/jbc.M309579200 [Abstract] [Full Text] [PDF]  

Mario Lorenz, Silja Wessler, Elena Follmann, Wanda Michaelis, Thomas Düsterhöft, Gert Baumann, Karl Stangl, and Verena Stangl
A Constituent of Green Tea, Epigallocatechin-3-gallate, Activates Endothelial Nitric Oxide Synthase by a Phosphatidylinositol-3-OH-kinase-, cAMP-dependent Protein Kinase-, and Akt-dependent Pathway and Leads to Endothelial-dependent Vasorelaxation
J. Biol. Chem. 2004 279: 6190-6195. First Published on November 24, 2003; doi:10.1074/jbc.M309114200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Alla S. Kostyukova and Sarah E. Hitchcock-DeGregori
Effect of the Structure of the N Terminus of Tropomyosin on Tropomodulin Function
J. Biol. Chem. 2004 279: 5066-5071. First Published on December 2, 2003; doi:10.1074/jbc.M311186200 [Abstract] [Full Text] [PDF]  

Sébastien Almagro, Daniel Riveline, Tatsuya Hirano, Bahram Houchmandzadeh, and Stefan Dimitrov
The Mitotic Chromosome Is an Assembly of Rigid Elastic Axes Organized by Structural Maintenance of Chromosomes (SMC) Proteins and Surrounded by a Soft Chromatin Envelope
J. Biol. Chem. 2004 279: 5118-5126. First Published on December 1, 2003; doi:10.1074/jbc.M307221200 [Abstract] [Full Text] [PDF]  

Simon J. Atkinson, Melanie A. Hosford, and Bruce A. Molitoris
Mechanism of Actin Polymerization in Cellular ATP Depletion
J. Biol. Chem. 2004 279: 5194-5199. First Published on November 17, 2003; doi:10.1074/jbc.M306973200 [Abstract] [Full Text] [PDF]  

Matthew R. Jones and Katya Ravid
Vascular Smooth Muscle Polyploidization as a Biomarker for Aging and Its Impact on Differential Gene Expression
J. Biol. Chem. 2004 279: 5306-5313. First Published on November 22, 2003; doi:10.1074/jbc.M308406200 [Abstract] [Full Text] [PDF] Supplemental Data  

Susan M. Keenan, Nathan H. Lents, and Joseph J. Baldassare
Expression of Cyclin E Renders Cyclin D-CDK4 Dispensable for Inactivation of the Retinoblastoma Tumor Suppressor Protein, Activation of E2F, and G1-S Phase Progression
J. Biol. Chem. 2004 279: 5387-5396. First Published on November 25, 2003; doi:10.1074/jbc.M310383200 [Abstract] [Full Text] [PDF]  

Eappen G. Abraham, Shabana Islam, Prakash Srinivasan, Anil K. Ghosh, Jesus G. Valenzuela, Jose M. C. Ribeiro, Fotis C. Kafatos, George Dimopoulos, and Marcelo Jacobs-Lorena
Analysis of the Plasmodium and Anopheles Transcriptional Repertoire during Ookinete Development and Midgut Invasion
J. Biol. Chem. 2004 279: 5573-5580. First Published on November 19, 2003; doi:10.1074/jbc.M307582200 [Abstract] [Full Text] [PDF] Supplemental Data  

Prakash Srinivasan, Eappen G. Abraham, Anil K. Ghosh, Jesus Valenzuela, Jose M. C. Ribeiro, George Dimopoulos, Fotis C. Kafatos, John H. Adams, Hisashi Fujioka, and Marcelo Jacobs-Lorena
Analysis of the Plasmodium and Anopheles Transcriptomes during Oocyst Differentiation
J. Biol. Chem. 2004 279: 5581-5587. First Published on November 19, 2003; doi:10.1074/jbc.M307587200 [Abstract] [Full Text] [PDF] Supplemental Data  

Sally P. Wheatley, Alexander J. Henzing, Helen Dodson, Walid Khaled, and William C. Earnshaw
Aurora-B Phosphorylation in Vitro Identifies a Residue of Survivin That Is Essential for Its Localization and Binding to Inner Centromere Protein (INCENP) in Vivo
J. Biol. Chem. 2004 279: 5655-5660. First Published on November 10, 2003; doi:10.1074/jbc.M311299200 [Abstract] [Full Text] [PDF]  

Shumpei Niida, Miyuki Kawahara, Yasuyuki Ishizuka, Yoshitaka Ikeda, Takako Kondo, Terumasa Hibi, Yu Suzuki, Kyoji Ikeda, and Naoyuki Taniguchi
{gamma}-Glutamyltranspeptidase Stimulates Receptor Activator of Nuclear Factor-{kappa}B Ligand Expression Independent of Its Enzymatic Activity and Serves as a Pathological Bone-resorbing Factor
J. Biol. Chem. 2004 279: 5752-5756. First Published on November 21, 2003; doi:10.1074/jbc.M311905200 [Abstract] [Full Text] [PDF]  

Xuerong Li, Huiqing Chen, Thein H. Oo, Thomas M. Daly, Lawrence W. Bergman, Shih-Chun Liu, Athar H. Chishti, and Steven S. Oh
A Co-ligand Complex Anchors Plasmodium falciparum Merozoites to the Erythrocyte Invasion Receptor Band 3
J. Biol. Chem. 2004 279: 5765-5771. First Published on November 20, 2003; doi:10.1074/jbc.M308716200 [Abstract] [Full Text] [PDF]  

Paul A. Townsend, Tiziano M. Scarabelli, Sean M. Davidson, Richard A. Knight, David S. Latchman, and Anastasis Stephanou
STAT-1 Interacts with p53 to Enhance DNA Damage-induced Apoptosis
J. Biol. Chem. 2004 279: 5811-5820. First Published on November 5, 2003; doi:10.1074/jbc.M302637200 [Abstract] [Full Text] [PDF]  

Bernhard Trinczek, Miro Brajenovic, Andreas Ebneth, and Gerard Drewes
MARK4 Is a Novel Microtubule-associated Proteins/Microtubule Affinity-regulating Kinase That Binds to the Cellular Microtubule Network and to Centrosomes
J. Biol. Chem. 2004 279: 5915-5923. First Published on November 1, 2003; doi:10.1074/jbc.M304528200 [Abstract] [Full Text] [PDF]  

John K. Mensah, Takuya Ogawa, Hitesh Kapadia, Adriana C. Cavender, and Rena N. D'Souza
Functional Analysis of a Mutation in PAX9 Associated with Familial Tooth Agenesis in Humans
J. Biol. Chem. 2004 279: 5924-5933. First Published on November 7, 2003; doi:10.1074/jbc.M305648200 [Abstract] [Full Text] [PDF]  

Nobutaka Suzuki, Megumi Nakano, Naohito Nozaki, Shin-ichiro Egashira, Tuneko Okazaki, and Hiroshi Masumoto
CENP-B Interacts with CENP-C Domains Containing Mif2 Regions Responsible for Centromere Localization
J. Biol. Chem. 2004 279: 5934-5946. First Published on November 10, 2003; doi:10.1074/jbc.M306477200 [Abstract] [Full Text] [PDF]  

Sung-Jen Wei, Carol S. Trempus, Robin C. Ali, Laura A. Hansen, and Raymond W. Tennant
12-O-Tetradecanoylphorbol-13-acetate and UV Radiation-induced Nucleoside Diphosphate Protein Kinase B Mediates Neoplastic Transformation of Epidermal Cells
J. Biol. Chem. 2004 279: 5993-6004. First Published on November 17, 2003; doi:10.1074/jbc.M310820200 [Abstract] [Full Text] [PDF]  

Sarwar Hashmi, Jun Zhang, Yelena Oksov, and Sara Lustigman
The Caenorhabditis elegans Cathepsin Z-like Cysteine Protease, Ce-CPZ-1, Has a Multifunctional Role during the Worms' Development
J. Biol. Chem. 2004 279: 6035-6045. First Published on November 20, 2003; doi:10.1074/jbc.M312346200 [Abstract] [Full Text] [PDF]  

Cynthia M. Grimsley, Jason M. Kinchen, Annie-Carole Tosello-Trampont, Enrico Brugnera, Lisa B. Haney, Mingjian Lu, Qi Chen, Doris Klingele, Michael O. Hengartner, and Kodi S. Ravichandran
Dock180 and ELMO1 Proteins Cooperate to Promote Evolutionarily Conserved Rac-dependent Cell Migration
J. Biol. Chem. 2004 279: 6087-6097. First Published on November 24, 2003; doi:10.1074/jbc.M307087200 [Abstract] [Full Text] [PDF] Supplemental Data  

Victoria A. Ploplis, Rashna Balsara, Mayra J. Sandoval-Cooper, Zhi Jun Yin, Jennifer Batten, Nayan Modi, Daniel Gadoua, Deborah Donahue, J. Andrew Martin, and Francis J. Castellino
Enhanced in Vitro Proliferation of Aortic Endothelial Cells from Plasminogen Activator Inhibitor-1-deficient Mice
J. Biol. Chem. 2004 279: 6143-6151. First Published on November 18, 2003; doi:10.1074/jbc.M307297200 [Abstract] [Full Text] [PDF]  

Torsten Wittmann, Gary M. Bokoch, and Clare M. Waterman-Storer
Regulation of Microtubule Destabilizing Activity of Op18/Stathmin Downstream of Rac1
J. Biol. Chem. 2004 279: 6196-6203. First Published on November 26, 2003; doi:10.1074/jbc.M307261200 [Abstract] [Full Text] [PDF] Supplemental Data  


Additions and Corrections:

Timothy Smith, John McCracken, Yeon-Kyun Shin, and David L. DeWitt
Arachidonic acid and nonsteroidal anti-inflammatory drugs induce conformational changes in the human prostaglandin endoperoxide H2 synthase-2 (cyclooxygenase-2). Vol. 275 (2000) 40407-40415
J. Biol. Chem. 2004 279: 6204. [Full Text] [PDF]  

Parimal Sheth, Shyamali Basuroy, Chunying Li, Anjaparavanda P. Naren, and Radhakrishna K. Rao
Role of phosphatidylinositol 3-kinase in oxidative stress-induced disruption of tight junctions. Vol. 278 (2003) 49239-49245
J. Biol. Chem. 2004 279: 6204. [Full Text] [PDF]  


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