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Table of Contents: Feb 20 2004; 279 (8)   [Index by Author]  [Cover Figure and Caption]
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Genomics, Proteomics, and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Accelerated Publications:

Kanamarlapudi Venkateswarlu, Kevin G. Brandom, and Joanna L. Lawrence
Centaurin-{alpha}1 Is an in Vivo Phosphatidylinositol 3,4,5-Trisphosphate-dependent GTPase-activating Protein for ARF6 That Is Involved in Actin Cytoskeleton Organization
J. Biol. Chem. 2004 279: 6205-6208. First Published on November 18, 2003; doi:10.1074/jbc.C300482200 [Abstract] [Full Text] [PDF]  

Xiaoyun Fu, Jeff L. F. Kao, Constanze Bergt, Sean Y. Kassim, Nabiha P. Huq, André d'Avignon, William C. Parks, Robert P. Mecham, and Jay W. Heinecke
Oxidative Cross-linking of Tryptophan to Glycine Restrains Matrix Metalloproteinase Activity: SPECIFIC STRUCTURAL MOTIFS CONTROL PROTEIN OXIDATION
J. Biol. Chem. 2004 279: 6209-6212. First Published on December 11, 2003; doi:10.1074/jbc.C300506200 [Abstract] [Full Text] [PDF]  

Paul R. Hinton, Mary G. Johlfs, Joanna M. Xiong, Kelly Hanestad, Kelly C. Ong, Chuck Bullock, Stephen Keller, Meina Tao Tang, J. Yun Tso, Max Vásquez, and Naoya Tsurushita
Engineered Human IgG Antibodies with Longer Serum Half-lives in Primates
J. Biol. Chem. 2004 279: 6213-6216. First Published on December 29, 2003; doi:10.1074/jbc.C300470200 [Abstract] [Full Text] [PDF]  

Reijiro Arakawa, Michi Hayashi, Alan T. Remaley, Bryan H. Brewer, Yoshio Yamauchi, and Shinji Yokoyama
Phosphorylation and Stabilization of ATP Binding Cassette Transporter A1 by Synthetic Amphiphilic Helical Peptides
J. Biol. Chem. 2004 279: 6217-6220. First Published on December 29, 2003; doi:10.1074/jbc.C300553200 [Abstract] [Full Text] [PDF]  

Aravind Basavapathruni, Christopher M. Bailey, and Karen S. Anderson
Defining a Molecular Mechanism of Synergy between Nucleoside and Nonnucleoside AIDS Drugs
J. Biol. Chem. 2004 279: 6221-6224. First Published on January 13, 2004; doi:10.1074/jbc.C300523200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:

Justin B. Robbins, Mary C. Murphy, Bryan A. White, Roderick I. Mackie, Taekjip Ha, and Isaac K. O. Cann
Functional Analysis of Multiple Single-stranded DNA-binding Proteins from Methanosarcina acetivorans and Their Effects on DNA Synthesis by DNA Polymerase BI
J. Biol. Chem. 2004 279: 6315-6326. First Published on December 4, 2003; doi:10.1074/jbc.M304491200 [Abstract] [Full Text] [PDF]  

Shuo-Xing Dou, Peng-Ye Wang, Hou Qiang Xu, and Xu Guang Xi
The DNA Binding Properties of the Escherichia coli RecQ Helicase
J. Biol. Chem. 2004 279: 6354-6363. First Published on December 9, 2003; doi:10.1074/jbc.M311272200 [Abstract] [Full Text] [PDF]  

Alexandre A. Vetcher and Robert D. Wells
Sticky DNA Formation in Vivo Alters the Plasmid Dimer/Monomer Ratio
J. Biol. Chem. 2004 279: 6434-6443. First Published on November 18, 2003; doi:10.1074/jbc.M309595200 [Abstract] [Full Text] [PDF]  

Marek Napierala, Ruhee Dere, Alexandre Vetcher, and Robert D. Wells
Structure-dependent Recombination Hot Spot Activity of GAA·TTC Sequences from Intron 1 of the Friedreich's Ataxia Gene
J. Biol. Chem. 2004 279: 6444-6454. First Published on November 18, 2003; doi:10.1074/jbc.M309596200 [Abstract] [Full Text] [PDF]  

Kefei Yu, Feng-Ting Huang, and Michael R. Lieber
DNA Substrate Length and Surrounding Sequence Affect the Activation-induced Deaminase Activity at Cytidine
J. Biol. Chem. 2004 279: 6496-6500. First Published on November 25, 2003; doi:10.1074/jbc.M311616200 [Abstract] [Full Text] [PDF]  

Mayuresh M. Abhyankar, Jagan M. Reddy, Rahul Sharma, Erika Büllesbach, and Deepak Bastia
Biochemical Investigations of Control of Replication Initiation of Plasmid R6K
J. Biol. Chem. 2004 279: 6711-6719. First Published on December 9, 2003; doi:10.1074/jbc.M312052200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Khampoune Sayasith, Nadine Bouchard, Michèle Sawadogo, Jacques G. Lussier, and Jean Sirois
Molecular Characterization and Role of Bovine Upstream Stimulatory Factor 1 and 2 in the Regulation of the Prostaglandin G/H Synthase-2 Promoter in Granulosa Cells
J. Biol. Chem. 2004 279: 6327-6336. First Published on December 5, 2003; doi:10.1074/jbc.M311222200 [Abstract] [Full Text] [PDF]  

Cyrus V. Hedvat, JinJuan Yao, Robert A. Sokolic, and Stephen D. Nimer
Myeloid ELF1-like Factor Is a Potent Activator of Interleukin-8 Expression in Hematopoietic Cells
J. Biol. Chem. 2004 279: 6395-6400. First Published on November 17, 2003; doi:10.1074/jbc.M307524200 [Abstract] [Full Text] [PDF]  

Enrique Lara-Pezzi, Nieves Pezzi, Ignacio Prieto, Isabel Barthelemy, Candelas Carreiro, Alicia Martínez, Alejandra Maldonado-Rodríguez, Manuel López-Cabrera, and José Luis Barbero
Evidence of a Transcriptional Co-activator Function of Cohesin STAG/SA/Scc3
J. Biol. Chem. 2004 279: 6553-6559. First Published on December 2, 2003; doi:10.1074/jbc.M307663200 [Abstract] [Full Text] [PDF]  

Wei Tan, Lei Zheng, Wen-Hwa Lee, and Thomas G. Boyer
Functional Dissection of Transcription Factor ZBRK1 Reveals Zinc Fingers with Dual Roles in DNA-binding and BRCA1-dependent Transcriptional Repression
J. Biol. Chem. 2004 279: 6576-6587. First Published on December 2, 2003; doi:10.1074/jbc.M312270200 [Abstract] [Full Text] [PDF]  

Kalpana Ghoshal, Sarmila Majumder, Jharna Datta, Tasneem Motiwala, Shoumei Bai, Sudarshana M. Sharma, Wendy Frankel, and Samson T. Jacob
Role of Human Ribosomal RNA (rRNA) Promoter Methylation and of Methyl-CpG-binding Protein MBD2 in the Suppression of rRNA Gene Expression
J. Biol. Chem. 2004 279: 6783-6793. First Published on November 10, 2003; doi:10.1074/jbc.M309393200 [Abstract] [Full Text] [PDF]  

Seung Joon Baek, Jong-Sik Kim, Jennifer B. Nixon, Richard P. DiAugustine, and Thomas E. Eling
Expression of NAG-1, a Transforming Growth Factor-{beta} Superfamily Member, by Troglitazone Requires the Early Growth Response Gene EGR-1
J. Biol. Chem. 2004 279: 6883-6892. First Published on December 8, 2003; doi:10.1074/jbc.M305295200 [Abstract] [Full Text] [PDF]  

Cristy L. Gelling, Matthew D. W. Piper, Seung-Pyo Hong, Geoffrey D. Kornfeld, and Ian W. Dawes
Identification of a Novel One-carbon Metabolism Regulon in Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 7072-7081. First Published on November 26, 2003; doi:10.1074/jbc.M309178200 [Abstract] [Full Text] [PDF] Supplemental Data  

Anne M. Curtis, Sang-beom Seo, Elizabeth J. Westgate, Radu Daniel Rudic, Emer M. Smyth, Debabrata Chakravarti, Garret A. FitzGerald, and Peter McNamara
Histone Acetyltransferase-dependent Chromatin Remodeling and the Vascular Clock
J. Biol. Chem. 2004 279: 7091-7097. First Published on November 26, 2003; doi:10.1074/jbc.M311973200 [Abstract] [Full Text] [PDF]  

Christopher W. Gregory, Xiaoyin Fei, Liliana A. Ponguta, Bin He, Heather M. Bill, Frank S. French, and Elizabeth M. Wilson
Epidermal Growth Factor Increases Coactivation of the Androgen Receptor in Recurrent Prostate Cancer
J. Biol. Chem. 2004 279: 7119-7130. First Published on December 8, 2003; doi:10.1074/jbc.M307649200 [Abstract] [Full Text] [PDF]  

Young-Hwa Goo, Soon-Young Na, Hao Zhang, Jianming Xu, SunHwa Hong, JaeHun Cheong, Soo-Kyung Lee, and Jae Woon Lee
Interactions between Activating Signal Cointegrator-2 and the Tumor Suppressor Retinoblastoma in Androgen Receptor Transactivation
J. Biol. Chem. 2004 279: 7131-7135. First Published on November 25, 2003; doi:10.1074/jbc.M312563200 [Abstract] [Full Text] [PDF]  

Sonja Eichmüller, Valeria Vezzoli, Claudia Bazzini, Markus Ritter, Johannes Fürst, Martin Jakab, Andrea Ravasio, Sabine Chwatal, Silvia Dossena, Guido Bottà, Giuliano Meyer, Brigitte Maier, Giovanna Valenti, Florian Lang, and Markus Paulmichl
A New Gene-finding Tool: USING THE CAENORHABDITIS ELEGANS OPERONS FOR IDENTIFYING FUNCTIONAL PARTNER PROTEINS IN HUMAN CELLS
J. Biol. Chem. 2004 279: 7136-7146. First Published on November 13, 2003; doi:10.1074/jbc.M307347200 [Abstract] [Full Text] [PDF]  

Catarina Sacristán, María Isabel Tussié-Luna, Sheila M. Logan, and Ananda L. Roy
Mechanism of Bruton's Tyrosine Kinase-mediated Recruitment and Regulation of TFII-I
J. Biol. Chem. 2004 279: 7147-7158. First Published on November 17, 2003; doi:10.1074/jbc.M303724200 [Abstract] [Full Text] [PDF]  

Kazunori Tanaka, Junko Shouguchi-Miyata, Natsuki Miyamoto, and Joh-E Ikeda
Novel Nuclear Shuttle Proteins, HDBP1 and HDBP2, Bind to Neuronal Cell-specific cis-Regulatory Element in the Promoter for the Human Huntington's Disease Gene
J. Biol. Chem. 2004 279: 7275-7286. First Published on November 18, 2003; doi:10.1074/jbc.M310726200 [Abstract] [Full Text] [PDF]  

Sonali Das, Simone Visosky Ward, Danielle Markle, and Charles E. Samuel
DNA Damage-binding Proteins and Heterogeneous Nuclear Ribonucleoprotein A1 Function as Constitutive KCS Element Components of the Interferon-inducible RNA-dependent Protein Kinase Promoter
J. Biol. Chem. 2004 279: 7313-7321. First Published on November 28, 2003; doi:10.1074/jbc.M312585200 [Abstract] [Full Text] [PDF]  

Haruhiko Ishii, Ranjan Sen, and Michael J. Pazin
Combinatorial Control of DNase I-hypersensitive Site Formation and Erasure by Immunoglobulin Heavy Chain Enhancer-binding Proteins
J. Biol. Chem. 2004 279: 7331-7338. First Published on December 1, 2003; doi:10.1074/jbc.M308973200 [Abstract] [Full Text] [PDF]  

Audrey O'Sullivan, Hua-Chen Chang, Qing Yu, and Mark H. Kaplan
STAT4 Is Required for Interleukin-12-induced Chromatin Remodeling of the CD25 Locus
J. Biol. Chem. 2004 279: 7339-7345. First Published on December 2, 2003; doi:10.1074/jbc.M309979200 [Abstract] [Full Text] [PDF]  


RNA: Structure, Metabolism, and Catalysis:

John S. Reader, David Metzgar, Paul Schimmel, and Valérie de Crécy-Lagard
Identification of Four Genes Necessary for Biosynthesis of the Modified Nucleoside Queuosine
J. Biol. Chem. 2004 279: 6280-6285. First Published on December 2, 2003; doi:10.1074/jbc.M310858200 [Abstract] [Full Text] [PDF] Supplemental Data  

Naoyuki Kataoka and Gideon Dreyfuss
A Simple Whole Cell Lysate System for in Vitro Splicing Reveals a Stepwise Assembly of the Exon-Exon Junction Complex
J. Biol. Chem. 2004 279: 7009-7013. First Published on November 18, 2003; doi:10.1074/jbc.M307692200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:

Peizhen Yang, Hongyong Fu, Joseph Walker, Charles M. Papa, Jan Smalle, Yu-Ming Ju, and Richard D. Vierstra
Purification of the Arabidopsis 26 S Proteasome: BIOCHEMICAL AND MOLECULAR ANALYSES REVEALED THE PRESENCE OF MULTIPLE ISOFORMS
J. Biol. Chem. 2004 279: 6401-6413. First Published on November 17, 2003; doi:10.1074/jbc.M311977200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ognyan K. Argirov, Bin Lin, and Beryl J. Ortwerth
2-Ammonio-6-(3-oxidopyridinium-1-yl)hexanoate (OP-lysine) Is a Newly Identified Advanced Glycation End Product in Cataractous and Aged Human Lenses
J. Biol. Chem. 2004 279: 6487-6495. First Published on November 21, 2003; doi:10.1074/jbc.M309090200 [Abstract] [Full Text] [PDF]  

Yicheng Zhang and Stuart A. Berger
Increased Calcium Influx and Ribosomal Content Correlate with Resistance to Endoplasmic Reticulum Stress-induced Cell Death in Mutant Leukemia Cell Lines
J. Biol. Chem. 2004 279: 6507-6516. First Published on December 1, 2003; doi:10.1074/jbc.M306117200 [Abstract] [Full Text] [PDF]  

Christopher B. Doering, John F. Healey, Ernest T. Parker, Rachel T. Barrow, and Pete Lollar
Identification of Porcine Coagulation Factor VIII Domains Responsible for High Level Expression via Enhanced Secretion
J. Biol. Chem. 2004 279: 6546-6552. First Published on December 1, 2003; doi:10.1074/jbc.M312451200 [Abstract] [Full Text] [PDF]  

Lee Ellen Brunson, Cheryl Dixon, Lukasz Kozubowski, and Neal Mathias
The Amino-terminal Portion of the F-box Protein Met30p Mediates Its Nuclear Import and Assimilation into an SCF Complex
J. Biol. Chem. 2004 279: 6674-6682. First Published on December 5, 2003; doi:10.1074/jbc.M308875200 [Abstract] [Full Text] [PDF]  

Gwang Lee, Mikiei Tanaka, Kiho Park, Sang Seop Lee, Yong Man Kim, Eunsung Junn, Sang-Hyeon Lee, and M. Maral Mouradian
Casein Kinase II-mediated Phosphorylation Regulates {alpha}-Synuclein/Synphilin-1 Interaction and Inclusion Body Formation
J. Biol. Chem. 2004 279: 6834-6839. First Published on November 26, 2003; doi:10.1074/jbc.M312760200 [Abstract] [Full Text] [PDF]  

Eran Barzilay, Nathalie Ben-Califa, Lia Supino-Rosin, Yoel Kashman, Koret Hirschberg, Zvulun Elazar, and Drorit Neumann
Geldanamycin-associated Inhibition of Intracellular Trafficking Is Attributed to a Co-purified Activity
J. Biol. Chem. 2004 279: 6847-6852. First Published on December 1, 2003; doi:10.1074/jbc.M312799200 [Abstract] [Full Text] [PDF]  

Karin Görner, Eve Holtorf, Sabine Odoy, Brigitte Nuscher, Ayako Yamamoto, Jörg T. Regula, Klaus Beyer, Christian Haass, and Philipp J. Kahle
Differential Effects of Parkinson's Disease-associated Mutations on Stability and Folding of DJ-1
J. Biol. Chem. 2004 279: 6943-6951. First Published on November 7, 2003; doi:10.1074/jbc.M309204200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:

Ivan Orlandi, Maurizio Bettiga, Lilia Alberghina, and Marina Vai
Transcriptional Profiling of ubp10 Null Mutant Reveals Altered Subtelomeric Gene Expression and Insurgence of Oxidative Stress Response
J. Biol. Chem. 2004 279: 6414-6425. First Published on November 17, 2003; doi:10.1074/jbc.M306464200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Bernard Metz, Gideon F. A. Kersten, Peter Hoogerhout, Humphrey F. Brugghe, Hans A. M. Timmermans, Ad de Jong, Hugo Meiring, Jan ten Hove, Wim E. Hennink, Daan J. A. Crommelin, and Wim Jiskoot
Identification of Formaldehyde-induced Modifications in Proteins: REACTIONS WITH MODEL PEPTIDES
J. Biol. Chem. 2004 279: 6235-6243. First Published on November 24, 2003; doi:10.1074/jbc.M310752200 [Abstract] [Full Text] [PDF]  

Ulrike Kappler, Kondo-Francois Aguey-Zinsou, Graeme R. Hanson, Paul V. Bernhardt, and Alastair G. McEwan
Cytochrome c551 from Starkeya novella: CHARACTERIZATION, SPECTROSCOPIC PROPERTIES, AND PHYLOGENY OF A DIHEME PROTEIN OF THE SoxAX FAMILY
J. Biol. Chem. 2004 279: 6252-6260. First Published on November 26, 2003; doi:10.1074/jbc.M310644200 [Abstract] [Full Text] [PDF]  

Giuseppina Andreotti and Andrea Motta
Modulating Calcitonin Fibrillogenesis: AN ANTIPARALLEL {alpha}-HELICAL DIMER INHIBITS FIBRILLATION OF SALMON CALCITONIN
J. Biol. Chem. 2004 279: 6364-6370. First Published on October 31, 2003; doi:10.1074/jbc.M310882200 [Abstract] [Full Text] [PDF]  

Ryoji Suno, Hideki Taguchi, Ryoji Masui, Masafumi Odaka, and Masasuke Yoshida
Trigger Factor from Thermus thermophilus Is a Zn2+-dependent Chaperone
J. Biol. Chem. 2004 279: 6380-6384. First Published on November 5, 2003; doi:10.1074/jbc.M311572200 [Abstract] [Full Text] [PDF]  

Aura Carreira, Margarita Menéndez, Juan Reguera, José María Almendral, and Mauricio G. Mateu
In Vitro Disassembly of a Parvovirus Capsid and Effect on Capsid Stability of Heterologous Peptide Insertions in Surface Loops
J. Biol. Chem. 2004 279: 6517-6525. First Published on December 1, 2003; doi:10.1074/jbc.M307662200 [Abstract] [Full Text] [PDF]  

Tomoo Ohashi and Harold P. Erickson
The Disulfide Bonding Pattern in Ficolin Multimers
J. Biol. Chem. 2004 279: 6534-6539. First Published on December 1, 2003; doi:10.1074/jbc.M310555200 [Abstract] [Full Text] [PDF]  

Takayuki Inuzuka, Bo-Geon Yun, Haruto Ishikawa, Satoshi Takahashi, Hiroshi Hori, Robert L. Matts, Koichiro Ishimori, and Isao Morishima
Identification of Crucial Histidines for Heme Binding in the N-terminal Domain of the Heme-regulated eIF2{alpha} Kinase
J. Biol. Chem. 2004 279: 6778-6782. First Published on December 12, 2003; doi:10.1074/jbc.C300464200 [Abstract] [Full Text] [PDF]  

Yasuaki Hiromasa, Tetsuro Fujisawa, Yoichi Aso, and Thomas E. Roche
Organization of the Cores of the Mammalian Pyruvate Dehydrogenase Complex Formed by E2 and E2 Plus the E3-binding Protein and Their Capacities to Bind the E1 and E3 Components
J. Biol. Chem. 2004 279: 6921-6933. First Published on November 24, 2003; doi:10.1074/jbc.M308172200 [Abstract] [Full Text] [PDF] Supplemental Data  

Christoph Heiring, Björn Dahlbäck, and Yves A. Muller
Ligand Recognition and Homophilic Interactions in Tyro3: STRUCTURAL INSIGHTS INTO THE Axl/Tyro3 RECEPTOR TYROSINE KINASE FAMILY
J. Biol. Chem. 2004 279: 6952-6958. First Published on November 17, 2003; doi:10.1074/jbc.M311750200 [Abstract] [Full Text] [PDF]  

Yong Wang, René Coulombe, Dale R. Cameron, Louise Thauvette, Marie-Josée Massariol, Lynn M. Amon, Dominique Fink, Steve Titolo, Ewald Welchner, Christiane Yoakim, Jacques Archambault, and Peter W. White
Crystal Structure of the E2 Transactivation Domain of Human Papillomavirus Type 11 Bound to a Protein Interaction Inhibitor
J. Biol. Chem. 2004 279: 6976-6985. First Published on November 22, 2003; doi:10.1074/jbc.M311376200 [Abstract] [Full Text] [PDF]  

Charles M. Forsyth, Donna Lemongello, Douglas J. LaCount, Paul D. Friesen, and Andrew J. Fisher
Crystal Structure of an Invertebrate Caspase
J. Biol. Chem. 2004 279: 7001-7008. First Published on November 27, 2003; doi:10.1074/jbc.M312472200 [Abstract] [Full Text] [PDF]  

Kerri M. Zawadzki and Susan S. Taylor
cAMP-dependent Protein Kinase Regulatory Subunit Type II{beta}: ACTIVE SITE MUTATIONS DEFINE AN ISOFORM-SPECIFIC NETWORK FOR ALLOSTERIC SIGNALING BY cAMP
J. Biol. Chem. 2004 279: 7029-7036. First Published on November 18, 2003; doi:10.1074/jbc.M310804200 [Abstract] [Full Text] [PDF]  

Ranjani Varadan, Michael Assfalg, Aydin Haririnia, Shahri Raasi, Cecile Pickart, and David Fushman
Solution Conformation of Lys63-linked Di-ubiquitin Chain Provides Clues to Functional Diversity of Polyubiquitin Signaling
J. Biol. Chem. 2004 279: 7055-7063. First Published on November 25, 2003; doi:10.1074/jbc.M309184200 [Abstract] [Full Text] [PDF] Supplemental Data  

Douglas A. Whittingtons, Jeffrey H. Grubb, Abdul Waheed, Gul N. Shah, William S. Sly, and David W. Christianson
Expression, Assay, and Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV: IMPLICATIONS FOR SELECTIVE INHIBITION OF MEMBRANE-ASSOCIATED ISOZYMES
J. Biol. Chem. 2004 279: 7223-7228. First Published on December 3, 2003; doi:10.1074/jbc.M310809200 [Abstract] [Full Text] [PDF]  

Kozo Yoneda, Tetsushi Furukawa, Ya-Juan Zheng, Takashi Momoi, Ichiro Izawa, Masaki Inagaki, Motomu Manabe, and Nobuya Inagaki
An Autocrine/Paracrine Loop Linking Keratin 14 Aggregates to Tumor Necrosis Factor {alpha}-mediated Cytotoxicity in a Keratinocyte Model of Epidermolysis Bullosa Simplex
J. Biol. Chem. 2004 279: 7296-7303. First Published on December 3, 2003; doi:10.1074/jbc.M307242200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Soufian Ouchane, Anne-Soisig Steunou, Martine Picaud, and Chantal Astier
Aerobic and Anaerobic Mg-Protoporphyrin Monomethyl Ester Cyclases in Purple Bacteria: A STRATEGY ADOPTED TO BYPASS THE REPRESSIVE OXYGEN CONTROL SYSTEM
J. Biol. Chem. 2004 279: 6385-6394. First Published on November 14, 2003; doi:10.1074/jbc.M309851200 [Abstract] [Full Text] [PDF]  

Pen-Jen Lin, David L. Straight, and Darrel W. Stafford
Binding of the Factor IX {gamma}-Carboxyglutamic Acid Domain to the Vitamin K-dependent {gamma}-Glutamyl Carboxylase Active Site Induces an Allosteric Effect That May Ensure Processive Carboxylation and Regulate the Release of Carboxylated Product
J. Biol. Chem. 2004 279: 6560-6566. First Published on December 2, 2003; doi:10.1074/jbc.M312239200 [Abstract] [Full Text] [PDF]  

Marijn van der Neut Kolfschoten, Richard J. Dirven, Hans L. Vos, Guido Tans, Jan Rosing, and Rogier M. Bertina
Factor Va Is Inactivated by Activated Protein C in the Absence of Cleavage Sites at Arg-306, Arg-506, and Arg-679
J. Biol. Chem. 2004 279: 6567-6575. First Published on December 2, 2003; doi:10.1074/jbc.M308574200 [Abstract] [Full Text] [PDF]  

Pauline F. Marx, Stefan R. Havik, J. Arnoud Marquart, Bonno N. Bouma, and Joost C. M. Meijers
Generation and Characterization of a Highly Stable Form of Activated Thrombin-activable Fibrinolysis Inhibitor
J. Biol. Chem. 2004 279: 6620-6628. First Published on December 4, 2003; doi:10.1074/jbc.M307337200 [Abstract] [Full Text] [PDF]  

Brian C. Tripp, Caleb B. Bell, III, Francisco Cruz, Carsten Krebs, and James G. Ferry
A Role for Iron in an Ancient Carbonic Anhydrase
J. Biol. Chem. 2004 279: 6683-6687. First Published on December 7, 2003; doi:10.1074/jbc.M311648200 [Abstract] [Full Text] [PDF]  

Luying Xun and Chris M. Webster
A Monooxygenase Catalyzes Sequential Dechlorinations of 2,4,6-Trichlorophenol by Oxidative and Hydrolytic Reactions
J. Biol. Chem. 2004 279: 6696-6700. First Published on December 7, 2003; doi:10.1074/jbc.M312072200 [Abstract] [Full Text] [PDF]  

Mark C. Sleeman and Christopher J. Schofield
Carboxymethylproline Synthase (CarB), an Unusual Carbon-Carbon Bond-forming Enzyme of the Crotonase Superfamily Involved in Carbapenem Biosynthesis
J. Biol. Chem. 2004 279: 6730-6736. First Published on November 18, 2003; doi:10.1074/jbc.M311824200 [Abstract] [Full Text] [PDF]  

Kenji Inaba, Yoh-hei Takahashi, and Koreaki Ito
DsbB Elicits a Red-shift of Bound Ubiquinone during the Catalysis of DsbA Oxidation
J. Biol. Chem. 2004 279: 6761-6768. First Published on November 20, 2003; doi:10.1074/jbc.M310765200 [Abstract] [Full Text] [PDF]  

Ann-Josée Noël, Wolfgang Wende, and Alfred Pingoud
DNA Recognition by the Homing Endonuclease PI-SceI Involves a Divalent Metal Ion Cofactor-induced Conformational Change
J. Biol. Chem. 2004 279: 6794-6804. First Published on November 21, 2003; doi:10.1074/jbc.M311372200 [Abstract] [Full Text] [PDF]  

Giuseppina De Simone, Luigi Mandrich, Valeria Menchise, Valeria Giordano, Ferdinando Febbraio, Mosè Rossi, Carlo Pedone, and Giuseppe Manco
A Substrate-induced Switch in the Reaction Mechanism of a Thermophilic Esterase: KINETIC EVIDENCES AND STRUCTURAL BASIS
J. Biol. Chem. 2004 279: 6815-6823. First Published on November 15, 2003; doi:10.1074/jbc.M307738200 [Abstract] [Full Text] [PDF]  

Shanmugham Dhanasekaran, Nagasuma R. Chandra, B. K. Chandrasekhar Sagar, Pundi N. Rangarajan, and Govindarajan Padmanaban
{delta}-Aminolevulinic Acid Dehydratase from Plasmodium falciparum: INDIGENOUS VERSUS IMPORTED
J. Biol. Chem. 2004 279: 6934-6942. First Published on November 24, 2003; doi:10.1074/jbc.M311409200 [Abstract] [Full Text] [PDF]  

Bijan Ahvazi, Karen M. Boeshans, William Idler, Ulrich Baxa, Peter M. Steinert, and Fraydoon Rastinejad
Structural Basis for the Coordinated Regulation of Transglutaminase 3 by Guanine Nucleotides and Calcium/Magnesium
J. Biol. Chem. 2004 279: 7180-7192. First Published on November 28, 2003; doi:10.1074/jbc.M312310200 [Abstract] [Full Text] [PDF]  

Akira Hirata, Motoyasu Adachi, Atsushi Sekine, You-Na Kang, Shigeru Utsumi, and Bunzo Mikami
Structural and Enzymatic Analysis of Soybean {beta}-Amylase Mutants with Increased pH Optimum
J. Biol. Chem. 2004 279: 7287-7295. First Published on November 24, 2003; doi:10.1074/jbc.M309411200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Damien Demozay, Stéphane Rocchi, Jean-Christophe Mas, Sophie Grillo, Luciano Pirola, Carine Chavey, and Emmanuel Van Obberghen
Fatty Aldehyde Dehydrogenase: POTENTIAL ROLE IN OXIDATIVE STRESS PROTECTION AND REGULATION OF ITS GENE EXPRESSION BY INSULIN
J. Biol. Chem. 2004 279: 6261-6270. First Published on November 24, 2003; doi:10.1074/jbc.M312062200 [Abstract] [Full Text] [PDF]  

Samuel S. Chuang, Christian Helvig, Mohammed Taimi, Heather A. Ramshaw, Andrew H. Collop, Ma'an Amad, Jay A. White, Martin Petkovich, Glenville Jones, and Bozena Korczak
CYP2U1, a Novel Human Thymus- and Brain-specific Cytochrome P450, Catalyzes {omega}- and ({omega}-1)-Hydroxylation of Fatty Acids
J. Biol. Chem. 2004 279: 6305-6314. First Published on December 3, 2003; doi:10.1074/jbc.M311830200 [Abstract] [Full Text] [PDF]  

Irene Baroli, Benjamin L. Gutman, Heidi K. Ledford, Jai W. Shin, Brian L. Chin, Michel Havaux, and Krishna K. Niyogi
Photo-oxidative Stress in a Xanthophyll-deficient Mutant of Chlamydomonas
J. Biol. Chem. 2004 279: 6337-6344. First Published on December 8, 2003; doi:10.1074/jbc.M312919200 [Abstract] [Full Text] [PDF]  

Uwe Sauer, Fabrizio Canonaco, Sylvia Heri, Annik Perrenoud, and Eliane Fischer
The Soluble and Membrane-bound Transhydrogenases UdhA and PntAB Have Divergent Functions in NADPH Metabolism of Escherichia coli
J. Biol. Chem. 2004 279: 6613-6619. First Published on December 3, 2003; doi:10.1074/jbc.M311657200 [Abstract] [Full Text] [PDF]  

Leonard J. Buccellato, May Tso, Ozkan I. Akinci, Navdeep S. Chandel, and G. R. Scott Budinger
Reactive Oxygen Species Are Required for Hyperoxia-induced Bax Activation and Cell Death in Alveolar Epithelial Cells
J. Biol. Chem. 2004 279: 6753-6760. First Published on November 18, 2003; doi:10.1074/jbc.M310145200 [Abstract] [Full Text] [PDF]  

Chang-Hyo Goh, Ki-Hong Jung, Stephen K. Roberts, Martin R. McAinsh, Alistair M. Hetherington, Youn-il Park, KyeHong Suh, Gynheung An, and Hong Gil Nam
Mitochondria Provide the Main Source of Cytosolic ATP for Activation of Outward-rectifying K+ Channels in Mesophyll Protoplast of Chlorophyll-deficient Mutant Rice (OsCHLH) Seedlings
J. Biol. Chem. 2004 279: 6874-6882. First Published on December 3, 2003; doi:10.1074/jbc.M309071200 [Abstract] [Full Text] [PDF]  

Raúl V. Durán, Manuel Hervás, Miguel A. De la Rosa, and José A. Navarro
The Efficient Functioning of Photosynthesis and Respiration in Synechocystis sp. PCC 6803 Strictly Requires the Presence of either Cytochrome c6 or Plastocyanin
J. Biol. Chem. 2004 279: 7229-7233. First Published on December 5, 2003; doi:10.1074/jbc.M311565200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Terrence F. Heathfield, Patrik Önnerfjord, Leif Dahlberg, and Dick Heinegård
Cleavage of Fibromodulin in Cartilage Explants Involves Removal of the N-terminal Tyrosine Sulfate-rich Region by Proteolysis at a Site That Is Sensitive to Matrix Metalloproteinase-13
J. Biol. Chem. 2004 279: 6286-6295. First Published on December 3, 2003; doi:10.1074/jbc.M307765200 [Abstract] [Full Text] [PDF]  

Christine Elm, Ranveig Braathen, Simone Bergmann, Ronald Frank, Jean-Pierre Vaerman, Charlotte S. Kaetzel, Gursharan S. Chhatwal, Finn-Eirik Johansen, and Sven Hammerschmidt
Ectodomains 3 and 4 of Human Polymeric Immunoglobulin Receptor (hpIgR) Mediate Invasion of Streptococcus pneumoniae into the Epithelium
J. Biol. Chem. 2004 279: 6296-6304. First Published on December 3, 2003; doi:10.1074/jbc.M310528200 [Abstract] [Full Text] [PDF] Supplemental Data  

Saulius Vainauskas and Anant K. Menon
A Conserved Proline in the Last Transmembrane Segment of Gaa1 Is Required for Glycosylphosphatidylinositol (GPI) Recognition by GPI Transamidase
J. Biol. Chem. 2004 279: 6540-6545. First Published on December 1, 2003; doi:10.1074/jbc.M312191200 [Abstract] [Full Text] [PDF]  

Silvia Goldoni, Rick T. Owens, David J. McQuillan, Zachary Shriver, Ram Sasisekharan, David E. Birk, Shelly Campbell, and Renato V. Iozzo
Biologically Active Decorin Is a Monomer in Solution
J. Biol. Chem. 2004 279: 6606-6612. First Published on December 3, 2003; doi:10.1074/jbc.M310342200 [Abstract] [Full Text] [PDF]  

Markus Böhm, Michael Raghunath, Cord Sunderkötter, Meinhard Schiller, Sonja Ständer, Thomas Brzoska, Thomas Cauvet, Helgi B. Schiöth, Thomas Schwarz, and Thomas A. Luger
Collagen Metabolism Is a Novel Target of the Neuropeptide {alpha}-Melanocyte-stimulating Hormone
J. Biol. Chem. 2004 279: 6959-6966. First Published on November 28, 2003; doi:10.1074/jbc.M312549200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Joseph Roitelman, Danièle Masson, Rachel Avner, Corinne Ammon-Zufferey, Anne Perez, Yves Guyon-Gellin, Craig L. Bentzen, and Eric J. Niesor
Apomine, a Novel Hypocholesterolemic Agent, Accelerates Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase and Stimulates Low Density Lipoprotein Receptor Activity
J. Biol. Chem. 2004 279: 6465-6473. First Published on November 19, 2003; doi:10.1074/jbc.M308094200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:

Tobias Schäfer, Hanswalter Zentgraf, Christoph Zehe, Britta Brügger, Jürgen Bernhagen, and Walter Nickel
Unconventional Secretion of Fibroblast Growth Factor 2 Is Mediated by Direct Translocation across the Plasma Membrane of Mammalian Cells
J. Biol. Chem. 2004 279: 6244-6251. First Published on November 27, 2003; doi:10.1074/jbc.M310500200 [Abstract] [Full Text] [PDF]  

Miguel R. Branco, H. Susana Marinho, Luisa Cyrne, and Fernando Antunes
Decrease of H2O2 Plasma Membrane Permeability during Adaptation to H2O2 in Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 6501-6506. First Published on November 26, 2003; doi:10.1074/jbc.M311818200 [Abstract] [Full Text] [PDF]  

Wen-I Wu and Dennis R. Voelker
Reconstitution of Phosphatidylserine Transport from Chemically Defined Donor Membranes to Phosphatidylserine Decarboxylase 2 Implicates Specific Lipid Domains in the Process
J. Biol. Chem. 2004 279: 6635-6642. First Published on December 4, 2003; doi:10.1074/jbc.M311570200 [Abstract] [Full Text] [PDF]  

Herwig Just, Harald H. Sitte, Johannes A. Schmid, Michael Freissmuth, and Oliver Kudlacek
Identification of an Additional Interaction Domain in Transmembrane Domains 11 and 12 That Supports Oligomer Formation in the Human Serotonin Transporter
J. Biol. Chem. 2004 279: 6650-6657. First Published on December 5, 2003; doi:10.1074/jbc.M306092200 [Abstract] [Full Text] [PDF]  

Yui-Ping Weng, Ya-Ping Lin, Chyong-Ing Hsu, and Jung-Yaw Lin
Functional Domains of a Pore-forming Cardiotoxic Protein, Volvatoxin A2
J. Biol. Chem. 2004 279: 6805-6814. First Published on November 28, 2003; doi:10.1074/jbc.M308675200 [Abstract] [Full Text] [PDF]  

Yolaine Dodier, Umberto Banderali, Hélène Klein, Özlem Topalak, Omar Dafi, Manuel Simoes, Gérald Bernatchez, Rémy Sauvé, and Lucie Parent
Outer Pore Topology of the ECaC-TRPV5 Channel by Cysteine Scan Mutagenesis
J. Biol. Chem. 2004 279: 6853-6862. First Published on November 20, 2003; doi:10.1074/jbc.M310534200 [Abstract] [Full Text] [PDF]  

Dana Yoo, Thomas P. Flagg, Olav Olsen, Viswanathan Raghuram, J. Kevin Foskett, and Paul A. Welling
Assembly and Trafficking of a Multiprotein ROMK (Kir 1.1) Channel Complex by PDZ Interactions
J. Biol. Chem. 2004 279: 6863-6873. First Published on November 5, 2003; doi:10.1074/jbc.M311599200 [Abstract] [Full Text] [PDF]  

Aaron Kolski-Andreaco, Hiroaki Tomita, Vikram G. Shakkottai, George A. Gutman, Michael D. Cahalan, J. Jay Gargus, and K. George Chandy
SK3-1C, a Dominant-negative Suppressor of SKCa and IKCa Channels
J. Biol. Chem. 2004 279: 6893-6904. First Published on November 24, 2003; doi:10.1074/jbc.M311725200 [Abstract] [Full Text] [PDF]  

Jae Man Lee, Seong-Hwan Rho, Dong Wook Shin, Chunghee Cho, Woo Jin Park, Soo Hyun Eom, Jianjie Ma, and Do Han Kim
Negatively Charged Amino Acids within the Intraluminal Loop of Ryanodine Receptor Are Involved in the Interaction with Triadin
J. Biol. Chem. 2004 279: 6994-7000. First Published on November 24, 2003; doi:10.1074/jbc.M312446200 [Abstract] [Full Text] [PDF]  

Liyan Zhang, Jong-Kook Lee, Scott A. John, Nobuyuki Uozumi, and Itsuo Kodama
Mechanosensitivity of GIRK Channels Is Mediated by Protein Kinase C-dependent Channel-Phosphatidylinositol 4,5-Bisphosphate Interaction
J. Biol. Chem. 2004 279: 7037-7047. First Published on December 1, 2003; doi:10.1074/jbc.M307323200 [Abstract] [Full Text] [PDF]  

Jooyoung Jung, Jae Soo Shin, Soon-Youl Lee, Sun Wook Hwang, Jaeyeon Koo, Hawon Cho, and Uhtaek Oh
Phosphorylation of Vanilloid Receptor 1 by Ca2+/Calmodulin-dependent Kinase II Regulates Its Vanilloid Binding
J. Biol. Chem. 2004 279: 7048-7054. First Published on November 20, 2003; doi:10.1074/jbc.M311448200 [Abstract] [Full Text] [PDF]  

Yoko Shiba, Yohei Katoh, Tomoo Shiba, Kaori Yoshino, Hiroyuki Takatsu, Hiromi Kobayashi, Hye-Won Shin, Soichi Wakatsuki, and Kazuhisa Nakayama
GAT (GGA and Tom1) Domain Responsible for Ubiquitin Binding and Ubiquitination
J. Biol. Chem. 2004 279: 7105-7111. First Published on December 2, 2003; doi:10.1074/jbc.M311702200 [Abstract] [Full Text] [PDF]  

Ming-Chuan Wang, Richard F. Collins, Robert C. Ford, Nicholas S. Berrow, Annette C. Dolphin, and Ashraf Kitmitto
The Three-dimensional Structure of the Cardiac L-type Voltage-gated Calcium Channel: COMPARISON WITH THE SKELETAL MUSCLE FORM REVEALS A COMMON ARCHITECTURAL MOTIF
J. Biol. Chem. 2004 279: 7159-7168. First Published on November 22, 2003; doi:10.1074/jbc.M308057200 [Abstract] [Full Text] [PDF]  

Richard H. Ho, Brenda F. Leake, Richard L. Roberts, Wooin Lee, and Richard B. Kim
Ethnicity-dependent Polymorphism in Na+-taurocholate Cotransporting Polypeptide (SLC10A1) Reveals a Domain Critical for Bile Acid Substrate Recognition
J. Biol. Chem. 2004 279: 7213-7222. First Published on December 2, 2003; doi:10.1074/jbc.M305782200 [Abstract] [Full Text] [PDF]  

Cristina Amat di San Filippo and Nicola Longo
Tyrosine Residues Affecting Sodium Stimulation of Carnitine Transport in the OCTN2 Carnitine/Organic Cation Transporter
J. Biol. Chem. 2004 279: 7247-7253. First Published on December 9, 2003; doi:10.1074/jbc.M309171200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Chris L. Lannon, Matthew J. Martin, Cristina E. Tognon, Wook Jin, Seong-Jin Kim, and Poul H. B. Sorensen
A Highly Conserved NTRK3 C-terminal Sequence in the ETV6-NTRK3 Oncoprotein Binds the Phosphotyrosine Binding Domain of Insulin Receptor Substrate-1: AN ESSENTIAL INTERACTION FOR TRANSFORMATION
J. Biol. Chem. 2004 279: 6225-6234. First Published on December 9, 2003; doi:10.1074/jbc.M307388200 [Abstract] [Full Text] [PDF]  

Lone S. Bertelsen, Kim E. Barrett, and Stephen J. Keely
Gs Protein-coupled Receptor Agonists Induce Transactivation of the Epidermal Growth Factor Receptor in T84 Cells: IMPLICATIONS FOR EPITHELIAL SECRETORY RESPONSES
J. Biol. Chem. 2004 279: 6271-6279. First Published on December 1, 2003; doi:10.1074/jbc.M311612200 [Abstract] [Full Text] [PDF]  

Hiroshi Kobayashi, Mika Suzuki, Naohiro Kanayama, and Toshihiko Terao
Genetic Down-regulation of Phosphoinositide 3-Kinase by Bikunin Correlates with Suppression of Invasion and Metastasis in Human Ovarian Cancer HRA Cells
J. Biol. Chem. 2004 279: 6371-6379. First Published on November 3, 2003; doi:10.1074/jbc.M305749200 [Abstract] [Full Text] [PDF]  

Jürgen Rettinger and Günther Schmalzing
Desensitization Masks Nanomolar Potency of ATP for the P2X1 Receptor
J. Biol. Chem. 2004 279: 6426-6433. First Published on November 18, 2003; doi:10.1074/jbc.M306987200 [Abstract] [Full Text] [PDF]  

Bogdan O. Popescu, Angel Cedazo-Minguez, Eirikur Benedikz, Takeshi Nishimura, Bengt Winblad, Maria Ankarcrona, and Richard F. Cowburn
{gamma}-Secretase Activity of Presenilin 1 Regulates Acetylcholine Muscarinic Receptor-mediated Signal Transduction
J. Biol. Chem. 2004 279: 6455-6464. First Published on November 18, 2003; doi:10.1074/jbc.M306041200 [Abstract] [Full Text] [PDF]  

Ahmed Osman, Edward G. Niles, and Philip T. LoVerde
Expression of Functional Schistosoma mansoni Smad4: ROLE IN ERK-MEDIATED TRANSFORMING GROWTH FACTOR {beta} (TGF-{beta}) DOWN-REGULATION
J. Biol. Chem. 2004 279: 6474-6486. First Published on November 20, 2003; doi:10.1074/jbc.M310949200 [Abstract] [Full Text] [PDF] Supplemental Data  

Mark Pellegrino, Emilia Furmaniak-Kazmierczak, Justin C. LeBlanc, Taewoo Cho, Kathy Cao, Santica M. Marcovina, Michael B. Boffa, Graham P. Côté, and Marlys L. Koschinsky
The Apolipoprotein(a) Component of Lipoprotein(a) Stimulates Actin Stress Fiber Formation and Loss of Cell-Cell Contact in Cultured Endothelial Cells
J. Biol. Chem. 2004 279: 6526-6533. First Published on December 1, 2003; doi:10.1074/jbc.M309705200 [Abstract] [Full Text] [PDF]  

Takayuki Yamada, Koichi Sato, Mayumi Komachi, Enkhzol Malchinkhuu, Masayuki Tobo, Takao Kimura, Atsushi Kuwabara, Yasuhiro Yanagita, Toshiro Ikeya, Yoshifumi Tanahashi, Tetsushi Ogawa, Susumu Ohwada, Yasuo Morishita, Hideo Ohta, Doon-Soon Im, Koichi Tamoto, Hideaki Tomura, and Fumikazu Okajima
Lysophosphatidic Acid (LPA) in Malignant Ascites Stimulates Motility of Human Pancreatic Cancer Cells through LPA1
J. Biol. Chem. 2004 279: 6595-6605. First Published on December 3, 2003; doi:10.1074/jbc.M308133200 [Abstract] [Full Text] [PDF]  

Kuniko Nakayama, Shu Okugawa, Shintaro Yanagimoto, Takatoshi Kitazawa, Kunihisa Tsukada, Miki Kawada, Satoshi Kimura, Koichi Hirai, Yohtaroh Takagaki, and Yasuo Ota
Involvement of IRAK-M in Peptidoglycan-induced Tolerance in Macrophages
J. Biol. Chem. 2004 279: 6629-6634. First Published on December 4, 2003; doi:10.1074/jbc.M308620200 [Abstract] [Full Text] [PDF]  

Kazuhiro Omori, Koji Naruishi, Fusanori Nishimura, Hisa Yamada-Naruishi, and Shogo Takashiba
High Glucose Enhances Interleukin-6-induced Vascular Endothelial Growth Factor 165 Expression via Activation of Gp130-mediated p44/42 MAPK-CCAAT/Enhancer Binding Protein Signaling in Gingival Fibroblasts
J. Biol. Chem. 2004 279: 6643-6649. First Published on December 4, 2003; doi:10.1074/jbc.M311688200 [Abstract] [Full Text] [PDF]  

Myungsoo Joo, Gye Young Park, Jeffrey G. Wright, Timothy S. Blackwell, Michael L. Atchison, and John W. Christman
Transcriptional Regulation of the Cyclooxygenase-2 Gene in Macrophages by PU.1
J. Biol. Chem. 2004 279: 6658-6665. First Published on December 5, 2003; doi:10.1074/jbc.M306267200 [Abstract] [Full Text] [PDF]  

Carol Heath and Nicholas C. P. Cross
Critical Role of STAT5 Activation in Transformation Mediated by ZNF198-FGFR1
J. Biol. Chem. 2004 279: 6666-6673. First Published on December 5, 2003; doi:10.1074/jbc.M308743200 [Abstract] [Full Text] [PDF]  

Shujun Ge and Joel S. Pachter
Caveolin-1 Knockdown by Small Interfering RNA Suppresses Responses to the Chemokine Monocyte Chemoattractant Protein-1 by Human Astrocytes
J. Biol. Chem. 2004 279: 6688-6695. First Published on December 5, 2003; doi:10.1074/jbc.M311769200 [Abstract] [Full Text] [PDF]  

Reema Goel, Polly J. Phillips-Mason, Alice Gardner, Daniel M. Raben, and Joseph J. Baldassare
{alpha}-Thrombin-mediated Phosphatidylinositol 3-Kinase Activation through Release of G{beta}{gamma} Dimers from G{alpha}q and G{alpha}i2
J. Biol. Chem. 2004 279: 6701-6710. First Published on December 9, 2003; doi:10.1074/jbc.M308753200 [Abstract] [Full Text] [PDF]  

Vi Pham, John D. Wade, Brooke W. Purdue, and Patrick M. Sexton
Spatial Proximity between a Photolabile Residue in Position 19 of Salmon Calcitonin and the Amino Terminus of the Human Calcitonin Receptor
J. Biol. Chem. 2004 279: 6720-6729. First Published on November 17, 2003; doi:10.1074/jbc.M307214200 [Abstract] [Full Text] [PDF]  

Xiaomei Qi, Stanley Borowicz, Rocky Pramanik, Richard M. Schultz, Jiahuai Han, and Guan Chen
Estrogen Receptor Inhibits c-Jun-dependent Stress-induced Cell Death by Binding and Modifying c-Jun Activity in Human Breast Cancer Cells
J. Biol. Chem. 2004 279: 6769-6777. First Published on November 24, 2003; doi:10.1074/jbc.M311492200 [Abstract] [Full Text] [PDF]  

Akiko Kimura, Ichiko Kinjyo, Yumiko Matsumura, Hiroyuki Mori, Ryuichi Mashima, Mine Harada, Kenneth R. Chien, Hideo Yasukawa, and Akihiko Yoshimura
SOCS3 Is a Physiological Negative Regulator for Granulopoiesis and Granulocyte Colony-stimulating Factor Receptor Signaling
J. Biol. Chem. 2004 279: 6905-6910. First Published on December 29, 2003; doi:10.1074/jbc.C300496200 [Abstract] [Full Text] [PDF]  

Dong Cho Han, Mi-Young Lee, Ki Deok Shin, Sun Bok Jeon, Jung Min Kim, Kwang-Hee Son, Hyoung-Chin Kim, Hwan-Mook Kim, and Byoung-Mog Kwon
2'-Benzoyloxycinnamaldehyde Induces Apoptosis in Human Carcinoma via Reactive Oxygen Species
J. Biol. Chem. 2004 279: 6911-6920. First Published on December 3, 2003; doi:10.1074/jbc.M309708200 [Abstract] [Full Text] [PDF]  

Éric Boué-Grabot, Michel B. Émerit, Estelle Toulmé, Philippe Séguéla, and Maurice Garret
Cross-talk and Co-trafficking between {rho}1/GABA Receptors and ATP-gated Channels
J. Biol. Chem. 2004 279: 6967-6975. First Published on December 1, 2003; doi:10.1074/jbc.M307772200 [Abstract] [Full Text] [PDF]  

Yusuke Yoshida and Kohji Hasunuma
Reactive Oxygen Species Affect Photomorphogenesis in Neurospora crassa
J. Biol. Chem. 2004 279: 6986-6993. First Published on November 17, 2003; doi:10.1074/jbc.M310060200 [Abstract] [Full Text] [PDF]  

Masaaki Nakayama, Miyuki Kimura, Akihiro Wada, Kinnosuke Yahiro, Ken-ichi Ogushi, Takuro Niidome, Akihiro Fujikawa, Daisuke Shirasaka, Nobuo Aoyama, Hisao Kurazono, Masaharu Noda, Joel Moss, and Toshiya Hirayama
Helicobacter pylori VacA Activates the p38/Activating Transcription Factor 2-mediated Signal Pathway in AZ-521 Cells
J. Biol. Chem. 2004 279: 7024-7028. First Published on November 20, 2003; doi:10.1074/jbc.M308898200 [Abstract] [Full Text] [PDF]  

Melanie A. Stegman, John A. Goetz, Manuel Ascano, Jr., Stacey K. Ogden, Kent E. Nybakken, and David J. Robbins
The Kinesin-related Protein Costal2 Associates with Membranes in a Hedgehog-sensitive, Smoothened-independent Manner
J. Biol. Chem. 2004 279: 7064-7071. First Published on November 28, 2003; doi:10.1074/jbc.M311794200 [Abstract] [Full Text] [PDF]  

Seon-Myung Kim, Min Seong Kwon, Chun Shik Park, Kyeong-Rock Choi, Jang-Soo Chun, Joohong Ahn, and Woo Keun Song
Modulation of Thr Phosphorylation of Integrin {beta}1 during Muscle Differentiation
J. Biol. Chem. 2004 279: 7082-7090. First Published on December 2, 2003; doi:10.1074/jbc.M311581200 [Abstract] [Full Text] [PDF]  

Radovan Dvorsky, Lars Blumenstein, Ingrid R. Vetter, and Mohammad Reza Ahmadian
Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA
J. Biol. Chem. 2004 279: 7098-7104. First Published on December 2, 2003; doi:10.1074/jbc.M311911200 [Abstract] [Full Text] [PDF]  

Xi-Long Zheng, Yu Gui, Guangwei Du, Michael A. Frohman, and Dao-Quan Peng
Calphostin-C Induction of Vascular Smooth Muscle Cell Apoptosis Proceeds through Phospholipase D and Microtubule Inhibition
J. Biol. Chem. 2004 279: 7112-7118. First Published on December 6, 2003; doi:10.1074/jbc.M310721200 [Abstract] [Full Text] [PDF]  

Shin'ichi Saito, Xiu-Fen Liu, Keiju Kamijo, Razi Raziuddin, Takashi Tatsumoto, Isamu Okamoto, Xiaoyan Chen, Chong-Chou Lee, Matthew V. Lorenzi, Naoya Ohara, and Toru Miki
Deregulation and Mislocalization of the Cytokinesis Regulator ECT2 Activate the Rho Signaling Pathways Leading to Malignant Transformation
J. Biol. Chem. 2004 279: 7169-7179. First Published on November 25, 2003; doi:10.1074/jbc.M306725200 [Abstract] [Full Text] [PDF]  

Michiru Nishita, Yan Wang, Chinatsu Tomizawa, Akira Suzuki, Ryusuke Niwa, Tadashi Uemura, and Kensaku Mizuno
Phosphoinositide 3-Kinase-mediated Activation of Cofilin Phosphatase Slingshot and Its Role for Insulin-induced Membrane Protrusion
J. Biol. Chem. 2004 279: 7193-7198. First Published on November 26, 2003; doi:10.1074/jbc.M312591200 [Abstract] [Full Text] [PDF]  

Sophie Vasseur, Emma Folch-Puy, Verena Hlouschek, Stephane Garcia, Fritz Fiedler, Markus M. Lerch, Jean Charles Dagorn, Daniel Closa, and Juan Lucio Iovanna
p8 Improves Pancreatic Response to Acute Pancreatitis by Enhancing the Expression of the Anti-inflammatory Protein Pancreatitis-associated Protein I
J. Biol. Chem. 2004 279: 7199-7207. First Published on December 1, 2003; doi:10.1074/jbc.M309152200 [Abstract] [Full Text] [PDF]  

Ling-Yu Chen, Bruce L. Zuraw, Richard D. Ye, and Zhixing K. Pan
A Rho Exchange Factor Mediates fMet-Leu-Phe-induced NF-{kappa}B Activation in Human Peripheral Blood Monocytes
J. Biol. Chem. 2004 279: 7208-7212. First Published on December 1, 2003; doi:10.1074/jbc.M309542200 [Abstract] [Full Text] [PDF]  

Michiko Yamasaki, Roser Masgrau, Anthony J. Morgan, Grant C. Churchill, Sandip Patel, Stephen J. H. Ashcroft, and Antony Galione
Organelle Selection Determines Agonist-specific Ca2+ Signals in Pancreatic Acinar and {beta} Cells
J. Biol. Chem. 2004 279: 7234-7240. First Published on December 2, 2003; doi:10.1074/jbc.M311088200 [Abstract] [Full Text] [PDF]  

Sylvie Cayouette, Marc P. Lussier, Eve-Lyne Mathieu, Simon M. Bousquet, and Guylain Boulay
Exocytotic Insertion of TRPC6 Channel into the Plasma Membrane upon Gq Protein-coupled Receptor Activation
J. Biol. Chem. 2004 279: 7241-7246. First Published on December 8, 2003; doi:10.1074/jbc.M312042200 [Abstract] [Full Text] [PDF]  

Susanne U. Miedlich, Lucio Gama, Klaus Seuwen, Romain M. Wolf, and Gerda E. Breitwieser
Homology Modeling of the Transmembrane Domain of the Human Calcium Sensing Receptor and Localization of an Allosteric Binding Site
J. Biol. Chem. 2004 279: 7254-7263. First Published on December 2, 2003; doi:10.1074/jbc.M307191200 [Abstract] [Full Text] [PDF]  

Jaesook Roh, Chia Lin Chang, Alka Bhalla, Cynthia Klein, and Sheau Yu Teddy Hsu
Intermedin Is a Calcitonin/Calcitonin Gene-related Peptide Family Peptide Acting through the Calcitonin Receptor-like Receptor/Receptor Activity-modifying Protein Receptor Complexes
J. Biol. Chem. 2004 279: 7264-7274. First Published on November 13, 2003; doi:10.1074/jbc.M305332200 [Abstract] [Full Text] [PDF]  

Hélène Tronchère, Jocelyn Laporte, Caroline Pendaries, Claire Chaussade, Laurence Liaubet, Luciano Pirola, Jean-Louis Mandel, and Bernard Payrastre
Production of Phosphatidylinositol 5-Phosphate by the Phosphoinositide 3-Phosphatase Myotubularin in Mammalian Cells
J. Biol. Chem. 2004 279: 7304-7312. First Published on December 1, 2003; doi:10.1074/jbc.M311071200 [Abstract] [Full Text] [PDF]  

Julia Brill, Rainer Klocke, Dieter Paul, Detlev Boison, Nicolette Gouder, Norbert Klugbauer, Franz Hofmann, Cord-Michael Becker, and Kristina Becker
entla, a Novel Epileptic and Ataxic Cacna2d2 Mutant of the Mouse
J. Biol. Chem. 2004 279: 7322-7330. First Published on December 2, 2003; doi:10.1074/jbc.M308778200 [Abstract] [Full Text] [PDF]  

Vi K. Chiu, Joseph Silletti, Victoria Dinsell, Heidi Wiener, Kristina Loukeris, Guoming Ou, Mark R. Philips, and Michael H. Pillinger
Carboxyl Methylation of Ras Regulates Membrane Targeting and Effector Engagement
J. Biol. Chem. 2004 279: 7346-7352. First Published on December 2, 2003; doi:10.1074/jbc.M311602200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Alessandra Pollice, Vittorio Nasti, Raffaele Ronca, Maria Vivo, Marco Lo Iacono, Raffaele Calogero, Viola Calabrò, and Girolama La Mantia
Functional and Physical Interaction of the Human ARF Tumor Suppressor with Tat-binding Protein-1
J. Biol. Chem. 2004 279: 6345-6353. First Published on December 9, 2003; doi:10.1074/jbc.M310957200 [Abstract] [Full Text] [PDF]  

Clemens M. Franz and Anne J. Ridley
p120 Catenin Associates with Microtubules: INVERSE RELATIONSHIP BETWEEN MICROTUBULE BINDING AND RHO GTPase REGULATION
J. Biol. Chem. 2004 279: 6588-6594. First Published on December 2, 2003; doi:10.1074/jbc.M312812200 [Abstract] [Full Text] [PDF]  

Daniela Trisciuoglio, Angela Iervolino, Antonio Candiloro, Gabriella Fibbi, Maurizio Fanciulli, Uwe Zangemeister-Wittke, Gabriella Zupi, and Donatella Del Bufalo
bcl-2 Induction of Urokinase Plasminogen Activator Receptor Expression in Human Cancer Cells through Sp1 Activation: INVOLVEMENT OF ERK1/ERK2 ACTIVITY
J. Biol. Chem. 2004 279: 6737-6745. First Published on December 1, 2003; doi:10.1074/jbc.M308938200 [Abstract] [Full Text] [PDF]  

Takuro Arimura, Takeharu Hayashi, Hajime Terada, Su-Yeoun Lee, Qiang Zhou, Megumi Takahashi, Kazuo Ueda, Tatsuhito Nouchi, Shigeru Hohda, Makoto Shibutani, Masao Hirose, Ju Chen, Jeong-Euy Park, Michio Yasunami, Hideharu Hayashi, and Akinori Kimura
A Cypher/ZASP Mutation Associated with Dilated Cardiomyopathy Alters the Binding Affinity to Protein Kinase C
J. Biol. Chem. 2004 279: 6746-6752. First Published on December 3, 2003; doi:10.1074/jbc.M311849200 [Abstract] [Full Text] [PDF]  

Susanne Kloeker, Michael B. Major, David A. Calderwood, Mark H. Ginsberg, David A. Jones, and Mary C. Beckerle
The Kindler Syndrome Protein Is Regulated by Transforming Growth Factor-{beta} and Involved in Integrin-mediated Adhesion
J. Biol. Chem. 2004 279: 6824-6833. First Published on November 21, 2003; doi:10.1074/jbc.M307978200 [Abstract] [Full Text] [PDF]  

Takashi Sekiya, Shungo Adachi, Kazuyoshi Kohu, Tatsuya Yamada, Osamu Higuchi, Yoichi Furukawa, Yusuke Nakamura, Tsutomu Nakamura, Kousuke Tashiro, Satoru Kuhara, Susumu Ohwada, and Tetsu Akiyama
Identification of BMP and Activin Membrane-bound Inhibitor (BAMBI), an Inhibitor of Transforming Growth Factor-{beta} Signaling, as a Target of the {beta}-Catenin Pathway in Colorectal Tumor Cells
J. Biol. Chem. 2004 279: 6840-6846. First Published on December 1, 2003; doi:10.1074/jbc.M310876200 [Abstract] [Full Text] [PDF]  

Douglas E. Albrecht and Stanley C. Froehner
DAMAGE, a Novel {alpha}-Dystrobrevin-associated MAGE Protein in Dystrophin Complexes
J. Biol. Chem. 2004 279: 7014-7023. First Published on November 17, 2003; doi:10.1074/jbc.M312205200 [Abstract] [Full Text] [PDF]  

Christine Müller, Cornelis F. Calkhoven, Xiaojing Sha, and Achim Leutz
The CCAAT Enhancer-binding Protein {alpha} (C/EBP{alpha}) Requires a SWI/SNF Complex for Proliferation Arrest
J. Biol. Chem. 2004 279: 7353-7358. First Published on December 4, 2003; doi:10.1074/jbc.M312709200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Olga V. Proussakova, Natalia A. Rabaya, Anna B. Moshnikova, Ekaterina S. Telegina, Anton Turanov, Mike G. Nanazashvili, and Igor P. Beletsky
Oligomerization of soluble Fas antigen induces its cytotoxicity. Vol. 278 (2003) 36236-36241
J. Biol. Chem. 2004 279: 7359. [Full Text] [PDF]  

Jeff D. Campbell, Koji Koike, Christophe Moreau, Mark S. P. Sansom, Roger G. Deeley, and Susan P. C. Cole
Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1). Vol. 279 (2004) 463-468
J. Biol. Chem. 2004 279: 7360. [Full Text] [PDF]  


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