Reflections:

Gerald M. Edelman

Biochemistry and the Sciences of Recognition
J. Biol. Chem. 2004 279: 7361-7369. First Published on January 12, 2004; doi:10.1074/jbc.X400001200 [Full Text] [PDF]  

DNA: Replication, Repair, and Recombination:

Jung Eun Ko, Choong Won Kim, and Deok Ryong Kim

Amino Acid Residues in RAG1 Responsible for the Interaction with RAG2 during the V(D)J Recombination Process
J. Biol. Chem. 2004 279: 7715-7720. First Published on December 11, 2003; doi:10.1074/jbc.M311471200 [Abstract] [Full Text] [PDF]  

Alexandre Tremeau-Bravard, Thilo Riedl, Jean-Marc Egly, and Michael E. Dahmus

Fate of RNA Polymerase II Stalled at a Cisplatin Lesion
J. Biol. Chem. 2004 279: 7751-7759. First Published on December 12, 2003; doi:10.1074/jbc.M309853200 [Abstract] [Full Text] [PDF]  

Hao Jiang, Ashley E. Ross, and Stephen Desiderio

Cell Cycle-dependent Accumulation in Vivo of Transposition-competent Complexes between Recombination Signal Ends and Full-length RAG Proteins
J. Biol. Chem. 2004 279: 8478-8486. First Published on December 4, 2003; doi:10.1074/jbc.M311219200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Tomoyoshi Nakadai, Miho Shimada, Daisuke Shima, Hiroshi Handa, and Taka-aki Tamura

Specific Interaction with Transcription Factor IIA and Localization of the Mammalian TATA-binding Protein-like Protein (TLP/TRF2/TLF)
J. Biol. Chem. 2004 279: 7447-7455. First Published on October 21, 2003; doi:10.1074/jbc.M305412200 [Abstract] [Full Text] [PDF]  

Carol M. Kiekhaefer, Meghan E. Boyer, Kirby D. Johnson, and Emery H. Bresnick

A WW Domain-binding Motif within the Activation Domain of the Hematopoietic Transcription Factor NF-E2 Is Essential for Establishment of a Tissue-specific Histone Modification Pattern
J. Biol. Chem. 2004 279: 7456-7461. First Published on November 2, 2003; doi:10.1074/jbc.M309750200 [Abstract] [Full Text] [PDF]  

Matthias D. Kaeser, Stephanie Pebernard, and Richard D. Iggo

Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells
J. Biol. Chem. 2004 279: 7598-7605. First Published on December 9, 2003; doi:10.1074/jbc.M311732200 [Abstract] [Full Text] [PDF]  

Barbora Lubyova, Merrill J. Kellum, Augusto J. Frisancho, and Paula M. Pitha

Kaposi's Sarcoma-associated Herpesvirus-encoded vIRF-3 Stimulates the Transcriptional Activity of Cellular IRF-3 and IRF-7
J. Biol. Chem. 2004 279: 7643-7654. First Published on December 10, 2003; doi:10.1074/jbc.M309485200 [Abstract] [Full Text] [PDF]  

Abdelhalim Boukaba, Elena I. Georgieva, Fiona A. Myers, Alan W. Thorne, Gerardo López-Rodas, Colyn Crane-Robinson, and Luis Franco

A Short-range Gradient of Histone H3 Acetylation and Tup1p Redistribution at the Promoter of the Saccharomyces cerevisiae SUC2 Gene
J. Biol. Chem. 2004 279: 7678-7684. First Published on December 11, 2003; doi:10.1074/jbc.M310849200 [Abstract] [Full Text] [PDF]  

Francesca Di Leva, Maria Immacolata Ferrante, Francesca Demarchi, Antonella Caravelli, Maria Rosaria Matarazzo, Mauro Giacca, Michele D'Urso, Maurizio D'Esposito, and Annamaria Franzé

Human Synaptobrevin-like 1 Gene Basal Transcription Is Regulated through the Interaction of Selenocysteine tRNA Gene Transcription Activating Factor-Zinc Finger 143 Factors with Evolutionary Conserved Cis-elements
J. Biol. Chem. 2004 279: 7734-7739. First Published on December 12, 2003; doi:10.1074/jbc.M308140200 [Abstract] [Full Text] [PDF]  

Yoko Shimamoto, Junji Ishida, Kazuyuki Yamagata, Tomoko Saito, Hideki Kato, Toshiki Matsuoka, Keiko Hirota, Hiroaki Daitoku, Masaomi Nangaku, Kazuya Yamagata, Hiroshi Fujii, Jun Takeda, and Akiyoshi Fukamizu

Inhibitory Effect of the Small Heterodimer Partner on Hepatocyte Nuclear Factor-4 Mediates Bile Acid-induced Repression of the Human Angiotensinogen Gene
J. Biol. Chem. 2004 279: 7770-7776. First Published on December 12, 2003; doi:10.1074/jbc.M310577200 [Abstract] [Full Text] [PDF]  

Emanuela Rescalli, Silvia Saini, Cristina Bartocci, Leszek Rychlewski, Víctor de Lorenzo, and Giovanni Bertoni

Novel Physiological Modulation of the Pu Promoter of TOL Plasmid: NEGATIVE REGULATORY ROLE OF THE TURA PROTEIN OF PSEUDOMONAS PUTIDA IN THE RESPONSE TO SUBOPTIMAL GROWTH TEMPERATURES
J. Biol. Chem. 2004 279: 7777-7784. First Published on December 12, 2003; doi:10.1074/jbc.M310580200 [Abstract] [Full Text] [PDF]  

Gerry Melino, Francesca Bernassola, Marco Ranalli, Karen Yee, Wei Xing Zong, Marco Corazzari, Richard A. Knight, Doug R. Green, Craig Thompson, and Karen H. Vousden

p73 Induces Apoptosis via PUMA Transactivation and Bax Mitochondrial Translocation
J. Biol. Chem. 2004 279: 8076-8083. First Published on November 21, 2003; doi:10.1074/jbc.M307469200 [Abstract] [Full Text] [PDF]  

Margaret L. Grace, Mahesh B. Chandrasekharan, Timothy C. Hall, and Alison J. Crowe

Sequence and Spacing of TATA Box Elements Are Critical for Accurate Initiation from the -Phaseolin Promoter
J. Biol. Chem. 2004 279: 8102-8110. First Published on December 4, 2003; doi:10.1074/jbc.M309376200 [Abstract] [Full Text] [PDF]  

Jean-Philippe Lalonde, Raelene Lim, Evan Ingley, Peta A. Tilbrook, Martin J. Thompson, Ross McCulloch, Jennifer G Beaumont, Carol Wicking, Helen J. Eyre, Grant R. Sutherland, Kathy Howe, Ellen Solomon, James H. Williams, and S. Peter Klinken

HLS5, a Novel RBCC (Ring Finger, B Box, Coiled-coil) Family Member Isolated from a Hemopoietic Lineage Switch, Is a Candidate Tumor Suppressor
J. Biol. Chem. 2004 279: 8181-8189. First Published on December 8, 2003; doi:10.1074/jbc.M306751200 [Abstract] [Full Text] [PDF]  

David A. Schneider and Richard L. Gourse

Relationship between Growth Rate and ATP Concentration in Escherichia coli: A BIOASSAY FOR AVAILABLE CELLULAR ATP
J. Biol. Chem. 2004 279: 8262-8268. First Published on December 11, 2003; doi:10.1074/jbc.M311996200 [Abstract] [Full Text] [PDF]  

Alan P. Kumar, F. Javier Piedrafita, and Wanda F. Reynolds

Peroxisome Proliferator-activated Receptor Ligands Regulate Myeloperoxidase Expression in Macrophages by an Estrogen-dependent Mechanism Involving the -463GA Promoter Polymorphism
J. Biol. Chem. 2004 279: 8300-8315. First Published on December 10, 2003; doi:10.1074/jbc.M311625200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Andrew Mehle, Bettina Strack, Petronela Ancuta, Chengsheng Zhang, Mark McPike, and Dana Gabuzda

Vif Overcomes the Innate Antiviral Activity of APOBEC3G by Promoting Its Degradation in the Ubiquitin-Proteasome Pathway
J. Biol. Chem. 2004 279: 7792-7798. First Published on December 13, 2003; doi:10.1074/jbc.M313093200 [Abstract] [Full Text] [PDF]  

Martina Nebohácová, Dmitri A. Maslov, Arnold M. Falick, and Larry Simpson

The Effect of RNA Interference Down-regulation of RNA Editing 3'-Terminal Uridylyl Transferase (TUTase) 1 on Mitochondrial de Novo Protein Synthesis and Stability of Respiratory Complexes in Trypanosoma brucei
J. Biol. Chem. 2004 279: 7819-7825. First Published on December 16, 2003; doi:10.1074/jbc.M311360200 [Abstract] [Full Text] [PDF]  

Constanze Bergt, Xiaoyun Fu, Nabiha P. Huq, Jeff Kao, and Jay W. Heinecke

Lysine Residues Direct the Chlorination of Tyrosines in YXXK Motifs of Apolipoprotein A-I When Hypochlorous Acid Oxidizes High Density Lipoprotein
J. Biol. Chem. 2004 279: 7856-7866. First Published on December 3, 2003; doi:10.1074/jbc.M309046200 [Abstract] [Full Text] [PDF]  

Hidenori Watabe, Julio C. Valencia, Ken-ichi Yasumoto, Tsuneto Kushimoto, Hideya Ando, Jacqueline Muller, Wilfred D. Vieira, Masako Mizoguchi, Ettore Appella, and Vincent J. Hearing

Regulation of Tyrosinase Processing and Trafficking by Organellar pH and by Proteasome Activity
J. Biol. Chem. 2004 279: 7971-7981. First Published on November 21, 2003; doi:10.1074/jbc.M309714200 [Abstract] [Full Text] [PDF]  

Xiquan Liang, Yun Lu, Meredith Wilkes, Thomas A. Neubert, and Marilyn D. Resh

The N-terminal SH4 Region of the Src Family Kinase Fyn Is Modified by Methylation and Heterogeneous Fatty Acylation: ROLE IN MEMBRANE TARGETING, CELL ADHESION, AND SPREADING
J. Biol. Chem. 2004 279: 8133-8139. First Published on December 5, 2003; doi:10.1074/jbc.M311180200 [Abstract] [Full Text] [PDF]  

Naoto Inukai, Yuki Yamaguchi, Isao Kuraoka, Tomoko Yamada, Sachiko Kamijo, Junko Kato, Kiyoji Tanaka, and Hiroshi Handa

A Novel Hydrogen Peroxide-induced Phosphorylation and Ubiquitination Pathway Leading to RNA Polymerase II Proteolysis
J. Biol. Chem. 2004 279: 8190-8195. First Published on December 8, 2003; doi:10.1074/jbc.M311412200 [Abstract] [Full Text] [PDF]  

Chee Chew Lim, Christian Zuppinger, Xinxin Guo, Gabriela M. Kuster, Michiel Helmes, Hans M. Eppenberger, Thomas M. Suter, Ronglih Liao, and Douglas B. Sawyer

Anthracyclines Induce Calpain-dependent Titin Proteolysis and Necrosis in Cardiomyocytes
J. Biol. Chem. 2004 279: 8290-8299. First Published on December 14, 2003; doi:10.1074/jbc.M308033200 [Abstract] [Full Text] [PDF] Supplemental Data  

François Valentin, Mark C. Field, and John R. Tippins

The Mechanism of Oxidative Stress Stabilization of the Thromboxane Receptor in COS-7 Cells
J. Biol. Chem. 2004 279: 8316-8324. First Published on October 28, 2003; doi:10.1074/jbc.M306761200 [Abstract] [Full Text] [PDF]  

Monzy Thomas, Nahid Dadgar, Abhishek Aphale, Jennifer M. Harrell, Robin Kunkel, William B. Pratt, and Andrew P. Lieberman

Androgen Receptor Acetylation Site Mutations Cause Trafficking Defects, Misfolding, and Aggregation Similar to Expanded Glutamine Tracts
J. Biol. Chem. 2004 279: 8389-8395. First Published on December 11, 2003; doi:10.1074/jbc.M311761200 [Abstract] [Full Text] [PDF]  

Ryuya Fukunaga, Shuya Fukai, Ryuichiro Ishitani, Osamu Nureki, and Shigeyuki Yokoyama

Crystal Structures of the CP1 Domain from Thermus thermophilus Isoleucyl-tRNA Synthetase and Its Complex with L-Valine
J. Biol. Chem. 2004 279: 8396-8402. First Published on December 12, 2003; doi:10.1074/jbc.M312830200 [Abstract] [Full Text] [PDF]  

Takumi Kanazawa, Ikue Taneike, Ryuichiro Akaishi, Fumiaki Yoshizawa, Norihiko Furuya, Shinobu Fujimura, and Motoni Kadowaki

Amino Acids and Insulin Control Autophagic Proteolysis through Different Signaling Pathways in Relation to mTOR in Isolated Rat Hepatocytes
J. Biol. Chem. 2004 279: 8452-8459. First Published on November 10, 2003; doi:10.1074/jbc.M306337200 [Abstract] [Full Text] [PDF]  

Genomics, Proteomics, and Bioinformatics:

R. Jeremy Nichols and Paula Traktman

Characterization of Three Paralogous Members of the Mammalian Vaccinia Related Kinase Family
J. Biol. Chem. 2004 279: 7934-7946. First Published on November 25, 2003; doi:10.1074/jbc.M310813200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Laura J. Juszczak

Comparative Vibrational Spectroscopy of Intracellular Tau and Extracellular Collagen I Reveals Parallels of Gelation and Fibrillar Structure
J. Biol. Chem. 2004 279: 7395-7404. First Published on December 4, 2003; doi:10.1074/jbc.M309971200 [Abstract] [Full Text] [PDF]  

Siôn L. Williams, Isabelle Valnot, Pierre Rustin, and Jan-Willem Taanman

Cytochrome c Oxidase Subassemblies in Fibroblast Cultures from Patients Carrying Mutations in COX10, SCO1, or SURF1
J. Biol. Chem. 2004 279: 7462-7469. First Published on November 7, 2003; doi:10.1074/jbc.M309232200 [Abstract] [Full Text] [PDF]  

Eman Basha, Garrett J. Lee, Linda A. Breci, Andrew C. Hausrath, Nicole R. Buan, Kim C. Giese, and Elizabeth Vierling

The Identity of Proteins Associated with a Small Heat Shock Protein during Heat Stress in Vivo Indicates That These Chaperones Protect a Wide Range of Cellular Functions
J. Biol. Chem. 2004 279: 7566-7575. First Published on December 8, 2003; doi:10.1074/jbc.M310684200 [Abstract] [Full Text] [PDF]  

Dirk Fasshauer and Martin Margittai

A Transient N-terminal Interaction of SNAP-25 and Syntaxin Nucleates SNARE Assembly
J. Biol. Chem. 2004 279: 7613-7621. First Published on December 9, 2003; doi:10.1074/jbc.M312064200 [Abstract] [Full Text] [PDF]  

Ilia V. Baskakov

Autocatalytic Conversion of Recombinant Prion Proteins Displays a Species Barrier
J. Biol. Chem. 2004 279: 7671-7677. First Published on December 10, 2003; doi:10.1074/jbc.M310594200 [Abstract] [Full Text] [PDF]  

Aaron P. Yamniuk and Hans J. Vogel

Structurally Homologous Binding of Plant Calmodulin Isoforms to the Calmodulin-binding Domain of Vacuolar Calcium-ATPase
J. Biol. Chem. 2004 279: 7698-7707. First Published on December 11, 2003; doi:10.1074/jbc.M310763200 [Abstract] [Full Text] [PDF]  

Benjamin S. Frank, Didem Vardar, Athar H. Chishti, and C. James McKnight

The NMR Structure of Dematin Headpiece Reveals a Dynamic Loop That Is Conformationally Altered upon Phosphorylation at a Distal Site
J. Biol. Chem. 2004 279: 7909-7916. First Published on December 2, 2003; doi:10.1074/jbc.M310524200 [Abstract] [Full Text] [PDF]  

Belinda Bullard, Charles Ferguson, Ave Minajeva, Mark C. Leake, Mathias Gautel, Dietmar Labeit, Linlin Ding, Siegfried Labeit, Joseph Horwitz, Kevin R. Leonard, and Wolfgang A. Linke

Association of the Chaperone B-crystallin with Titin in Heart Muscle
J. Biol. Chem. 2004 279: 7917-7924. First Published on December 4, 2003; doi:10.1074/jbc.M307473200 [Abstract] [Full Text] [PDF]  

Yvonne Nymalm, J. Santeri Puranen, Thomas K. M. Nyholm, Jarmo Käpylä, Heidi Kidron, Olli T. Pentikäinen, Tomi T. Airenne, Jyrki Heino, J. Peter Slotte, Mark S. Johnson, and Tiina A. Salminen

Jararhagin-derived RKKH Peptides Induce Structural Changes in ₁I Domain of Human Integrin ₁₁
J. Biol. Chem. 2004 279: 7962-7970. First Published on December 4, 2003; doi:10.1074/jbc.M312912200 [Abstract] [Full Text] [PDF]  

Maxim S. Pometun, Eduard Y. Chekmenev, and Richard J. Wittebort

Quantitative Observation of Backbone Disorder in Native Elastin
J. Biol. Chem. 2004 279: 7982-7987. First Published on November 18, 2003; doi:10.1074/jbc.M310948200 [Abstract] [Full Text] [PDF]  

Vanesa Zylberman, Patricio O. Craig, Sebastián Klinke, Bradford C. Braden, Ana Cauerhff, and Fernando A. Goldbaum

High Order Quaternary Arrangement Confers Increased Structural Stability to Brucella sp. Lumazine Synthase
J. Biol. Chem. 2004 279: 8093-8101. First Published on December 1, 2003; doi:10.1074/jbc.M312035200 [Abstract] [Full Text] [PDF]  

Jose M. de Pereda, William F. Waas, Yiwen Jan, Erkki Ruoslahti, Paul Schimmel, and Jaime Pascual

Crystal Structure of a Human Peptidyl-tRNA Hydrolase Reveals a New Fold and Suggests Basis for a Bifunctional Activity
J. Biol. Chem. 2004 279: 8111-8115. First Published on December 5, 2003; doi:10.1074/jbc.M311449200 [Abstract] [Full Text] [PDF]  

Istvan Botos, Edward E. Melnikov, Scott Cherry, Joseph E. Tropea, Anna G. Khalatova, Fatima Rasulova, Zbigniew Dauter, Michael R. Maurizi, Tatyana V. Rotanova, Alexander Wlodawer, and Alla Gustchina

The Catalytic Domain of Escherichia coli Lon Protease Has a Unique Fold and a Ser-Lys Dyad in the Active Site
J. Biol. Chem. 2004 279: 8140-8148. First Published on December 9, 2003; doi:10.1074/jbc.M312243200 [Abstract] [Full Text] [PDF]  

Lior Cohen, Izhar Karbat, Nicolas Gilles, Oren Froy, Gerardo Corzo, Ruthie Angelovici, Dalia Gordon, and Michael Gurevitz

Dissection of the Functional Surface of an Anti-insect Excitatory Toxin Illuminates a Putative "Hot Spot" Common to All Scorpion -Toxins Affecting Na⁺ Channels
J. Biol. Chem. 2004 279: 8206-8211. First Published on December 12, 2003; doi:10.1074/jbc.M307531200 [Abstract] [Full Text] [PDF]  

Izhack Cherny and Ehud Gazit

The YefM Antitoxin Defines a Family of Natively Unfolded Proteins: IMPLICATIONS AS A NOVEL ANTIBACTERIAL TARGET
J. Biol. Chem. 2004 279: 8252-8261. First Published on December 14, 2003; doi:10.1074/jbc.M308263200 [Abstract] [Full Text] [PDF]  

David Bhella, Ian G. Goodfellow, Pietro Roversi, David Pettigrew, Yasmin Chaudhry, David J. Evans, and Susan M. Lea

The Structure of Echovirus Type 12 Bound to a Two-domain Fragment of Its Cellular Attachment Protein Decay-accelerating Factor (CD 55)
J. Biol. Chem. 2004 279: 8325-8332. First Published on November 21, 2003; doi:10.1074/jbc.M311334200 [Abstract] [Full Text] [PDF]  

Nicolas Leulliot, Sophie Quevillon-Cheruel, Isabelle Sorel, Ines Li de La Sierra-Gallay, Bruno Collinet, Marc Graille, Karine Blondeau, Nabila Bettache, Anne Poupon, Joël Janin, and Herman van Tilbeurgh

Structure of Protein Phosphatase Methyltransferase 1 (PPM1), a Leucine Carboxyl Methyltransferase Involved in the Regulation of Protein Phosphatase 2A Activity
J. Biol. Chem. 2004 279: 8351-8358. First Published on December 4, 2003; doi:10.1074/jbc.M311484200 [Abstract] [Full Text] [PDF]  

Frederic Rousseau, Joost W. H. Schymkowitz, Hannah R. Wilkinson, and Laura S. Itzhaki

Intermediates Control Domain Swapping during Folding of p13^suc1
J. Biol. Chem. 2004 279: 8368-8377. First Published on December 7, 2003; doi:10.1074/jbc.M310640200 [Abstract] [Full Text] [PDF]  

Yadong Yu, Yunqing Liu, Ning Shen, Xiang Xu, Feng Xu, Jie Jia, Youxin Jin, Eddy Arnold, and Jianping Ding

Crystal Structure of Human Tryptophanyl-tRNA Synthetase Catalytic Fragment: INSIGHTS INTO SUBSTRATE RECOGNITION, tRNA BINDING, AND ANGIOGENESIS ACTIVITY
J. Biol. Chem. 2004 279: 8378-8388. First Published on December 5, 2003; doi:10.1074/jbc.M311284200 [Abstract] [Full Text] [PDF]  

Guanghua Gao, Kirk C. Prutzman, Michelle L. King, Danielle M. Scheswohl, Eugene F. DeRose, Robert E. London, Michael D. Schaller, and Sharon L. Campbell

NMR Solution Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase in Complex with a Paxillin LD Peptide: EVIDENCE FOR A TWO-SITE BINDING MODEL
J. Biol. Chem. 2004 279: 8441-8451. First Published on December 7, 2003; doi:10.1074/jbc.M309808200 [Abstract] [Full Text] [PDF] Supplemental Data  

Jamison D. Feramisco, Joseph L. Goldstein, and Michael S. Brown

Membrane Topology of Human Insig-1, a Protein Regulator of Lipid Synthesis
J. Biol. Chem. 2004 279: 8487-8496. First Published on December 5, 2003; doi:10.1074/jbc.M312623200 [Abstract] [Full Text] [PDF]  

James A. Olzmann, Keith Brown, Keith D. Wilkinson, Howard D. Rees, Qing Huai, Hengming Ke, Allan I. Levey, Lian Li, and Lih-Shen Chin

Familial Parkinson's Disease-associated L166P Mutation Disrupts DJ-1 Protein Folding and Function
J. Biol. Chem. 2004 279: 8506-8515. First Published on December 9, 2003; doi:10.1074/jbc.M311017200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Valerie Grimminger, Klaus Richter, Axel Imhof, Johannes Buchner, and Stefan Walter

The Prion Curing Agent Guanidinium Chloride Specifically Inhibits ATP Hydrolysis by Hsp104
J. Biol. Chem. 2004 279: 7378-7383. First Published on December 10, 2003; doi:10.1074/jbc.M312403200 [Abstract] [Full Text] [PDF]  

Nadine Kessler, Holger Schuhmann, Sabrina Morneweg, Uwe Linne, and Mohamed A. Marahiel

The Linear Pentadecapeptide Gramicidin Is Assembled by Four Multimodular Nonribosomal Peptide Synthetases That Comprise 16 Modules with 56 Catalytic Domains
J. Biol. Chem. 2004 279: 7413-7419. First Published on December 11, 2003; doi:10.1074/jbc.M309658200 [Abstract] [Full Text] [PDF]  

Catrine Johansson, Christopher Horst Lillig, and Arne Holmgren

Human Mitochondrial Glutaredoxin Reduces S-Glutathionylated Proteins with High Affinity Accepting Electrons from Either Glutathione or Thioredoxin Reductase
J. Biol. Chem. 2004 279: 7537-7543. First Published on December 4, 2003; doi:10.1074/jbc.M312719200 [Abstract] [Full Text] [PDF]  

Xiangbo Zhao, Stefania Girotto, Shengwei Yu, and Richard S. Magliozzo

Evidence for Radical Formation at Tyr-353 in Mycobacterium tuberculosis Catalase-Peroxidase (KatG)
J. Biol. Chem. 2004 279: 7606-7612. First Published on December 9, 2003; doi:10.1074/jbc.M311884200 [Abstract] [Full Text] [PDF]  

Julien Dairou, Noureddine Atmane, Fernando Rodrigues-Lima, and Jean-Marie Dupret

Peroxynitrite Irreversibly Inactivates the Human Xenobioticmetabolizing Enzyme Arylamine N-Acetyltransferase 1 (NAT1) in Human Breast Cancer Cells: A CELLULAR AND MECHANISTIC STUDY
J. Biol. Chem. 2004 279: 7708-7714. First Published on December 11, 2003; doi:10.1074/jbc.M311469200 [Abstract] [Full Text] [PDF]  

Carsten Berndt, Christopher H. Lillig, Markus Wollenberg, Eckhard Bill, María C. Mansilla, Diego de Mendoza, Andreas Seidler, and Jens D. Schwenn

Characterization and Reconstitution of a 4Fe-4S Adenylyl Sulfate/Phosphoadenylyl Sulfate Reductase from Bacillus subtilis
J. Biol. Chem. 2004 279: 7850-7855. First Published on November 19, 2003; doi:10.1074/jbc.M309332200 [Abstract] [Full Text] [PDF]  

Yasuhiro Nishiyama, Gita Bhatia, Yogesh Bangale, Stephanie Planque, Yukie Mitsuda, Hiroaki Taguchi, Sangeeta Karle, and Sudhir Paul

Toward Selective Covalent Inactivation of Pathogenic Antibodies: A PHOSPHONATE DIESTER ANALOG OF VASOACTIVE INTESTINAL PEPTIDE THAT INACTIVATES CATALYTIC AUTOANTIBODIES
J. Biol. Chem. 2004 279: 7877-7883. First Published on December 15, 2003; doi:10.1074/jbc.M310950200 [Abstract] [Full Text] [PDF]  

Allison A. Johnson, Jane M. Sayer, Haruhiko Yagi, Govind P. Kalena, Ronak Amin, Donald M. Jerina, and Yves Pommier

Position-specific Suppression and Enhancement of HIV-1 Integrase Reactions by Minor Groove Benzo[a]pyrene Diol Epoxide Deoxyguanine Adducts: IMPLICATIONS FOR MOLECULAR INTERACTIONS BETWEEN INTEGRASE AND DNA SUBSTRATES
J. Biol. Chem. 2004 279: 7947-7955. First Published on November 18, 2003; doi:10.1074/jbc.M311263200 [Abstract] [Full Text] [PDF] Supplemental Data  

David Rodríguez, Luis M. Quirós, and José A. Salas

MtmMII-mediated C-Methylation during Biosynthesis of the Antitumor Drug Mithramycin Is Essential for Biological Activity and DNA-Drug Interaction
J. Biol. Chem. 2004 279: 8149-8158. First Published on December 5, 2003; doi:10.1074/jbc.M312351200 [Abstract] [Full Text] [PDF]  

Yi I. Wu, Hidayatullah G. Munshi, Ratna Sen, Scott J. Snipas, Guy S. Salvesen, Rafael Fridman, and M. Sharon Stack

Glycosylation Broadens the Substrate Profile of Membrane Type 1 Matrix Metalloproteinase
J. Biol. Chem. 2004 279: 8278-8289. First Published on December 11, 2003; doi:10.1074/jbc.M311870200 [Abstract] [Full Text] [PDF]  

Alejandra Yep, Miguel A. Ballicora, Mirta N. Sivak, and Jack Preiss

Identification and Characterization of a Critical Region in the Glycogen Synthase from Escherichia coli
J. Biol. Chem. 2004 279: 8359-8367. First Published on December 9, 2003; doi:10.1074/jbc.M312686200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Ye Qi Liu, Jacob A. Moibi, and Jack L. Leahy

Chronic High Glucose Lowers Pyruvate Dehydrogenase Activity in Islets through Enhanced Production of Long Chain Acyl-CoA: PREVENTION OF IMPAIRED GLUCOSE OXIDATION BY ENHANCED PYRUVATE RECYCLING THROUGH THE MALATE-PYRUVATE SHUTTLE
J. Biol. Chem. 2004 279: 7470-7475. First Published on December 1, 2003; doi:10.1074/jbc.M307921200 [Abstract] [Full Text] [PDF]  

Caryn E. Outten and Valeria C. Culotta

Alternative Start Sites in the Saccharomyces cerevisiae GLR1 Gene Are Responsible for Mitochondrial and Cytosolic Isoforms of Glutathione Reductase
J. Biol. Chem. 2004 279: 7785-7791. First Published on December 12, 2003; doi:10.1074/jbc.M312421200 [Abstract] [Full Text] [PDF]  

Marc Schmidt, Frank Gerlach, Aaron Avivi, Tilmann Laufs, Sylvia Wystub, Jeremy C. Simpson, Eviatar Nevo, Sigrid Saaler-Reinhardt, Stefan Reuss, Thomas Hankeln, and Thorsten Burmester

Cytoglobin Is a Respiratory Protein in Connective Tissue and Neurons, Which Is Up-regulated by Hypoxia
J. Biol. Chem. 2004 279: 8063-8069. First Published on December 3, 2003; doi:10.1074/jbc.M310540200 [Abstract] [Full Text] [PDF] Supplemental Data  

Glycobiology and Extracellular Matrices:

Jane Reiland, Ralph D. Sanderson, Marian Waguespack, Steven A. Barker, Robert Long, Daniel D. Carson, and Dario Marchetti

Heparanase Degrades Syndecan-1 and Perlecan Heparan Sulfate: FUNCTIONAL IMPLICATIONS FOR TUMOR CELL INVASION
J. Biol. Chem. 2004 279: 8047-8055. First Published on November 20, 2003; doi:10.1074/jbc.M304872200 [Abstract] [Full Text] [PDF]  

Ken Nogami, Hiroaki Suzuki, Hiroko Habuchi, Naoki Ishiguro, Hisashi Iwata, and Koji Kimata

Distinctive Expression Patterns of Heparan Sulfate O-Sulfotransferases and Regional Differences in Heparan Sulfate Structure in Chick Limb Buds
J. Biol. Chem. 2004 279: 8219-8229. First Published on December 3, 2003; doi:10.1074/jbc.M307304200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Maxime Denis, Bassam Haidar, Michel Marcil, Michel Bouvier, Larbi Krimbou, and Jacques Genest, Jr.

Molecular and Cellular Physiology of Apolipoprotein A-I Lipidation by the ATP-binding Cassette Transporter A1 (ABCA1)
J. Biol. Chem. 2004 279: 7384-7394. First Published on December 4, 2003; doi:10.1074/jbc.M306963200 [Abstract] [Full Text] [PDF]  

Jennifer S. Dickinson Zimmer, Dennis R. Voelker, David A. Bernlohr, and Robert C. Murphy

Stabilization of Leukotriene A₄ by Epithelial Fatty Acid-binding Protein in the Rat Basophilic Leukemia Cell
J. Biol. Chem. 2004 279: 7420-7426. First Published on December 15, 2003; doi:10.1074/jbc.M311404200 [Abstract] [Full Text] [PDF]  

Gregory B. Tilton, Jay M. Shockey, and John Browse

Biochemical and Molecular Characterization of ACH2, an Acyl-CoA Thioesterase from Arabidopsis thaliana
J. Biol. Chem. 2004 279: 7487-7494. First Published on December 2, 2003; doi:10.1074/jbc.M309532200 [Abstract] [Full Text] [PDF]  

Tomonari Koike, Jingyan Liang, Xiaofei Wang, Tomonaga Ichikawa, Masashi Shiomi, George Liu, Huijun Sun, Shuji Kitajima, Masatoshi Morimoto, Teruo Watanabe, Nobuhiro Yamada, and Jianglin Fan

Overexpression of Lipoprotein Lipase in Transgenic Watanabe Heritable Hyperlipidemic Rabbits Improves Hyperlipidemia and Obesity
J. Biol. Chem. 2004 279: 7521-7529. First Published on December 3, 2003; doi:10.1074/jbc.M311514200 [Abstract] [Full Text] [PDF]  

Chongren Tang, Ashley M. Vaughan, and John F. Oram

Janus Kinase 2 Modulates the Apolipoprotein Interactions with ABCA1 Required for Removing Cellular Cholesterol
J. Biol. Chem. 2004 279: 7622-7628. First Published on December 9, 2003; doi:10.1074/jbc.M312571200 [Abstract] [Full Text] [PDF]  

Dominic S. Ng, Chunhui Xie, Graham F. Maguire, Xianghong Zhu, Francisca Ugwu, Eric Lam, and Philip W. Connelly

Hypertriglyceridemia in Lecithin-cholesterol Acyltransferase-deficient Mice Is Associated with Hepatic Overproduction of Triglycerides, Increased Lipogenesis, and Improved Glucose Tolerance
J. Biol. Chem. 2004 279: 7636-7642. First Published on December 10, 2003; doi:10.1074/jbc.M309439200 [Abstract] [Full Text] [PDF]  

María Fabiana De Rosa, Daniel Sillence, Cameron Ackerley, and Clifford Lingwood

Role of Multiple Drug Resistance Protein 1 in Neutral but Not Acidic Glycosphingolipid Biosynthesis
J. Biol. Chem. 2004 279: 7867-7876. First Published on December 8, 2003; doi:10.1074/jbc.M305645200 [Abstract] [Full Text] [PDF]  

Andrew R. Leventhal, Christina C. Leslie, and Ira Tabas

Suppression of Macrophage Eicosanoid Synthesis by Atherogenic Lipoproteins Is Profoundly Affected by Cholesterol-Fatty Acyl Esterification and the Niemann-Pick C Pathway of Lipid Trafficking
J. Biol. Chem. 2004 279: 8084-8092. First Published on November 24, 2003; doi:10.1074/jbc.M310672200 [Abstract] [Full Text] [PDF]  

Rie Yasuno, Penny von Wettstein-Knowles, and Hajime Wada

Identification and Molecular Characterization of the -Ketoacyl-[Acyl Carrier Protein] Synthase Component of the Arabidopsis Mitochondrial Fatty Acid Synthase
J. Biol. Chem. 2004 279: 8242-8251. First Published on December 2, 2003; doi:10.1074/jbc.M308894200 [Abstract] [Full Text] [PDF] Suplemental Data  

Anne Garcia, Vidya Subramanian, Anna Sekowski, Sucharita Bhattacharyya, Martha W. Love, and Dawn L. Brasaemle

The Amino and Carboxyl Termini of Perilipin A Facilitate the Storage of Triacylglycerols
J. Biol. Chem. 2004 279: 8409-8416. First Published on November 10, 2003; doi:10.1074/jbc.M311198200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Cezar M. Khursigara, Gregory De Crescenzo, Peter D. Pawelek, and James W. Coulton

Enhanced Binding of TonB to a Ligand-loaded Outer Membrane Receptor: ROLE OF THE OLIGOMERIC STATE OF TonB IN FORMATION OF A FUNCTIONAL FhuA·TonB COMPLEX
J. Biol. Chem. 2004 279: 7405-7412. First Published on December 10, 2003; doi:10.1074/jbc.M311784200 [Abstract] [Full Text] [PDF]  

Britta Brügger, Catriona Graham, Iris Leibrecht, Enrico Mombelli, Angela Jen, Felix Wieland, and Roger Morris

The Membrane Domains Occupied by Glycosylphosphatidylinositol-anchored Prion Protein and Thy-1 Differ in Lipid Composition
J. Biol. Chem. 2004 279: 7530-7536. First Published on December 4, 2003; doi:10.1074/jbc.M310207200 [Abstract] [Full Text] [PDF] Supplemental Data  

Takahiro Iwamoto, Satomi Kita, Akira Uehara, Issei Imanaga, Toshio Matsuda, Akemichi Baba, and Takeshi Katsuragi

Molecular Determinants of Na⁺/Ca²⁺ Exchange (NCX1) Inhibition by SEA0400
J. Biol. Chem. 2004 279: 7544-7553. First Published on December 5, 2003; doi:10.1074/jbc.M310491200 [Abstract] [Full Text] [PDF]  

Emilija Veljkovic, Susan Stasiuk, Patrick J. Skelly, Charles B. Shoemaker, and François Verrey

Functional Characterization of Caenorhabditis elegans Heteromeric Amino Acid Transporters
J. Biol. Chem. 2004 279: 7655-7662. First Published on December 10, 2003; doi:10.1074/jbc.M309528200 [Abstract] [Full Text] [PDF]  

Tip W. Loo, M. Claire Bartlett, and David M. Clarke

Disulfide Cross-linking Analysis Shows That Transmembrane Segments 5 and 8 of Human P-glycoprotein Are Close Together on the Cytoplasmic Side of the Membrane
J. Biol. Chem. 2004 279: 7692-7697. First Published on December 10, 2003; doi:10.1074/jbc.M311825200 [Abstract] [Full Text] [PDF]  

Jennifer F. Caplan, Nolan R. Filipenko, Sandra L. Fitzpatrick, and David M. Waisman

Regulation of Annexin A2 by Reversible Glutathionylation
J. Biol. Chem. 2004 279: 7740-7750. First Published on December 10, 2003; doi:10.1074/jbc.M313049200 [Abstract] [Full Text] [PDF]  

Anthony Lewis, Zoe A. McCrossan, and Geoffrey W. Abbott

MinK, MiRP1, and MiRP2 Diversify Kv3.1 and Kv3.2 Potassium Channel Gating
J. Biol. Chem. 2004 279: 7884-7892. First Published on December 16, 2003; doi:10.1074/jbc.M310501200 [Abstract] [Full Text] [PDF]  

Shih-Hua Chen, Michael R. Bubb, Elena G. Yarmola, Jian Zuo, Jin Jiang, Beth S. Lee, Ming Lu, Stephen L. Gluck, I. Rita Hurst, and L. Shannon Holliday

Vacuolar H⁺-ATPase Binding to Microfilaments: REGULATION IN RESPONSE TO PHOSPHATIDYLINOSITOL 3-KINASE ACTIVITY AND DETAILED CHARACTERIZATION OF THE ACTIN-BINDING SITE IN SUBUNIT B
J. Biol. Chem. 2004 279: 7988-7998. First Published on December 8, 2003; doi:10.1074/jbc.M305351200 [Abstract] [Full Text] [PDF]  

Rafael Mattera, Brigitte Ritter, Sachdev S. Sidhu, Peter S. McPherson, and Juan S. Bonifacino

Definition of the Consensus Motif Recognized by -Adaptin Ear Domains
J. Biol. Chem. 2004 279: 8018-8028. First Published on December 9, 2003; doi:10.1074/jbc.M311873200 [Abstract] [Full Text] [PDF]  

Amanda L. Horstman, Susanne J. Bauman, and Meta J. Kuehn

Lipopolysaccharide 3-Deoxy-D-manno-octulosonic Acid (Kdo) Core Determines Bacterial Association of Secreted Toxins
J. Biol. Chem. 2004 279: 8070-8075. First Published on December 4, 2003; doi:10.1074/jbc.M308633200 [Abstract] [Full Text] [PDF]  

Mica Ohara-Imaizumi, Chiyono Nishiwaki, Toshiteru Kikuta, Konosuke Kumakura, Yoko Nakamichi, and Shinya Nagamatsu

Site of Docking and Fusion of Insulin Secretory Granules in Live MIN6 Cells Analyzed by TAT-conjugated Anti-syntaxin 1 Antibody and Total Internal Reflection Fluorescence Microscopy
J. Biol. Chem. 2004 279: 8403-8408. First Published on December 15, 2003; doi:10.1074/jbc.M308954200 [Abstract] [Full Text] [PDF] Supplemental Data  

Hong-Long Ji, LaToya R. Bishop, Susan J. Anderson, Catherine M. Fuller, and Dale J. Benos

The Role of Pre-H2 Domains of - and -Epithelial Na⁺ Channels in Ion Permeation, Conductance, and Amiloride Sensitivity
J. Biol. Chem. 2004 279: 8428-8440. First Published on December 2, 2003; doi:10.1074/jbc.M312012200 [Abstract] [Full Text] [PDF]  

Naoko Takahashi, Yoshihiro Yamaguchi, Fumiko Yamairi, Masaki Makise, Hitomi Takenaka, Tomofusa Tsuchiya, and Tohru Mizushima

Analysis on Origin Recognition Complex containing Orc5p with defective Walker A Motif
J. Biol. Chem. 2004 279: 8469-8477. First Published on November 18, 2003; doi:10.1074/jbc.M305531200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Jong Sung Park, Daiva Svetkauskaite, Qianbin He, Jae-Yeol Kim, Derek Strassheim, Akitoshi Ishizaka, and Edward Abraham

Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein
J. Biol. Chem. 2004 279: 7370-7377. First Published on December 4, 2003; doi:10.1074/jbc.M306793200 [Abstract] [Full Text] [PDF]  

Dangsheng Li, Tatsuya Yamada, Fang Wang, A. Igor Vulin, and Herbert H. Samuels

Novel Roles of Retinoid X Receptor (RXR) and RXR Ligand in Dynamically Modulating the Activity of the Thyroid Hormone Receptor/RXR Heterodimer
J. Biol. Chem. 2004 279: 7427-7437. First Published on December 10, 2003; doi:10.1074/jbc.M311596200 [Abstract] [Full Text] [PDF]  

Wen Hong Shen, Yuxin Yin, Suzanne R. Broussard, Robert H. McCusker, Gregory G. Freund, Robert Dantzer, and Keith W. Kelley

Tumor Necrosis Factor Inhibits Cyclin A Expression and Retinoblastoma Hyperphosphorylation Triggered by Insulin-like Growth Factor-I Induction of New E2F-1 Synthesis
J. Biol. Chem. 2004 279: 7438-7446. First Published on December 16, 2003; doi:10.1074/jbc.M310264200 [Abstract] [Full Text] [PDF]  

Francesca Novi, Marco Scarselli, Giovanni U. Corsini, and Roberto Maggio

The Paired Activation of the Two Components of the Muscarinic M₃ Receptor Dimer Is Required for Induction of ERK1/2 Phosphorylation
J. Biol. Chem. 2004 279: 7476-7486. First Published on December 2, 2003; doi:10.1074/jbc.M306818200 [Abstract] [Full Text] [PDF]  

Robert M. Givens, Mei-Hui Lin, Derek J. Taylor, Undine Mechold, James O. Berry, and V. James Hernandez

Inducible Expression, Enzymatic Activity, and Origin of Higher Plant Homologues of Bacterial RelA/SpoT Stress Proteins in Nicotiana tabacum
J. Biol. Chem. 2004 279: 7495-7504. First Published on December 2, 2003; doi:10.1074/jbc.M311573200 [Abstract] [Full Text] [PDF] Supplemental Data  

Lazaros C. Foukas, George Panayotou, and Peter R. Shepherd

Direct Interaction of Major Histocompatibility Complex Class II-derived Peptides with Class Ia Phosphoinositide 3-Kinase Results in Dose-dependent Stimulatory Effects
J. Biol. Chem. 2004 279: 7505-7511. First Published on December 3, 2003; doi:10.1074/jbc.M303999200 [Abstract] [Full Text] [PDF]  

Sun Young Park, Inik Chang, Ja-Young Kim, Sang Won Kang, Se-Ho Park, Keshav Singh, and Myung-Shik Lee

Resistance of Mitochondrial DNA-depleted Cells against Cell Death: ROLE OF MITOCHONDRIAL SUPEROXIDE DISMUTASE
J. Biol. Chem. 2004 279: 7512-7520. First Published on December 3, 2003; doi:10.1074/jbc.M307677200 [Abstract] [Full Text] [PDF]  

Cristian Ibarra, Manuel Estrada, Loreto Carrasco, Mario Chiong, José L. Liberona, César Cardenas, Guillermo Díaz-Araya, Enrique Jaimovich, and Sergio Lavandero

Insulin-like Growth Factor-1 Induces an Inositol 1,4,5-Trisphosphate-dependent Increase in Nuclear and Cytosolic Calcium in Cultured Rat Cardiac Myocytes
J. Biol. Chem. 2004 279: 7554-7565. First Published on December 6, 2003; doi:10.1074/jbc.M311604200 [Abstract] [Full Text] [PDF]  

Ajoy K. Samanta, Helen J. Huang, Robert C. Bast, Jr., and Warren S.-L. Liao

Overexpression of MEKK3 Confers Resistance to Apoptosis through Activation of NFB
J. Biol. Chem. 2004 279: 7576-7583. First Published on December 8, 2003; doi:10.1074/jbc.M311659200 [Abstract] [Full Text] [PDF]  

Hee-Sae Park, Je-Wook Yu, Jun-Ho Cho, Mi-Sung Kim, Sung-Ho Huh, Kanghyun Ryoo, and Eui-Ju Choi

Inhibition of Apoptosis Signal-regulating Kinase 1 by Nitric Oxide through a Thiol Redox Mechanism
J. Biol. Chem. 2004 279: 7584-7590. First Published on December 9, 2003; doi:10.1074/jbc.M304183200 [Abstract] [Full Text] [PDF]  

Thi-Minh Nguyen, Michèle Lieberherr, Janine Fritsch, Huguette Guillozo, Maria Laura Alvarez, Zohra Fitouri, Frederic Jehan, and Michèle Garabédian

The Rapid Effects of 1,25-Dihydroxyvitamin D₃ Require the Vitamin D Receptor and Influence 24-Hydroxylase Activity: STUDIES IN HUMAN SKIN FIBROBLASTS BEARING VITAMIN D RECEPTOR MUTATIONS
J. Biol. Chem. 2004 279: 7591-7597. First Published on December 9, 2003; doi:10.1074/jbc.M309517200 [Abstract] [Full Text] [PDF]  

Kei Tamura, Tomoko Noyama, Yo-hei Ishizawa, Nobuhiko Takamatsu, Tadayoshi Shiba, and Michihiko Ito

Xenopus Death Receptor-M1 and -M2, New Members of the Tumor Necrosis Factor Receptor Superfamily, Trigger Apoptotic Signaling by Differential Mechanisms
J. Biol. Chem. 2004 279: 7629-7635. First Published on December 10, 2003; doi:10.1074/jbc.M306217200 [Abstract] [Full Text] [PDF]  

Eva Böhm, Gunter J. Sturm, Iris Weiglhofer, Hilary Sandig, Michitaka Shichijo, Anne McNamee, James E. Pease, Manfred Kollroser, Bernhard A. Peskar, and Akos Heinemann

11-Dehydro-thromboxane B₂, a Stable Thromboxane Metabolite, Is a Full Agonist of Chemoattractant Receptor-homologous Molecule Expressed on TH2 Cells (CRTH2) in Human Eosinophils and Basophils
J. Biol. Chem. 2004 279: 7663-7670. First Published on December 10, 2003; doi:10.1074/jbc.M310270200 [Abstract] [Full Text] [PDF]  

Matthew H. Brush, Amaris Guardiola, John H. Connor, Tso-Pang Yao, and Shirish Shenolikar

Deactylase Inhibitors Disrupt Cellular Complexes Containing Protein Phosphatases and Deacetylases
J. Biol. Chem. 2004 279: 7685-7691. First Published on December 10, 2003; doi:10.1074/jbc.M310997200 [Abstract] [Full Text] [PDF]  

Margaret S. Sozio, Meredith A. Mathis, Jennifer A. Young, Sebastien Wälchli, Lisa A. Pitcher, Philip C. Wrage, Beatrix Bartók, Amanda Campbell, Julian D. Watts, Ruedi Aebersold, Rob Hooft van Huijsduijnen, and Nicolai S. C. van Oers

PTPH1 Is a Predominant Protein-tyrosine Phosphatase Capable of Interacting with and Dephosphorylating the T Cell Receptor Subunit
J. Biol. Chem. 2004 279: 7760-7769. First Published on December 12, 2003; doi:10.1074/jbc.M309994200 [Abstract] [Full Text] [PDF]  

Carlos Reyes-Moreno, Julie Girouard, Rejean Lapointe, André Darveau, and Walid Mourad

CD40/CD40 Homodimers Are Required for CD40-induced Phosphatidylinositol 3-Kinase-dependent Expression of B7.2 by Human B Lymphocytes
J. Biol. Chem. 2004 279: 7799-7806. First Published on December 15, 2003; doi:10.1074/jbc.M313168200 [Abstract] [Full Text] [PDF]  

Seungkirl Ahn, Huijun Wei, Tiffany Runyan Garrison, and Robert J. Lefkowitz

Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by -Arrestins 1 and 2
J. Biol. Chem. 2004 279: 7807-7811. First Published on January 7, 2004; doi:10.1074/jbc.C300443200 [Abstract] [Full Text] [PDF]  

Hongtae Kim, Noh-Jin Kwak, Joo Yong Lee, Byung Hyune Choi, Young Lim, Young Jin Ko, Young-Hoon Kim, Pil-Woo Huh, Kweon-Haeng Lee, Hyoung Kyun Rha, and Young-Pil Wang

Merlin Neutralizes the Inhibitory Effect of Mdm2 on p53
J. Biol. Chem. 2004 279: 7812-7818. First Published on December 16, 2003; doi:10.1074/jbc.M305526200 [Abstract] [Full Text] [PDF]  

Bing-e Xu, Steve Stippec, Lisa Lenertz, Byung-Hoon Lee, Wei Zhang, Youn-Kyoung Lee, and Melanie H. Cobb

WNK1 Activates ERK5 by an MEKK2/3-dependent Mechanism
J. Biol. Chem. 2004 279: 7826-7831. First Published on December 16, 2003; doi:10.1074/jbc.M313465200 [Abstract] [Full Text] [PDF]  

Paschal A. Oude Weernink, Konstantinos Meletiadis, Silvia Hommeltenberg, Matthias Hinz, Hisamitsu Ishihara, Martina Schmidt, and Karl H. Jakobs

Activation of Type I Phosphatidylinositol 4-Phosphate 5-Kinase Isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42
J. Biol. Chem. 2004 279: 7840-7849. First Published on December 17, 2003; doi:10.1074/jbc.M312737200 [Abstract] [Full Text] [PDF]  

Dennis K. Lee, A. José Lança, Regina Cheng, Tuan Nguyen, Xiao Dong Ji, Fernand Gobeil, Jr., Sylvain Chemtob, Susan. R. George, and Brian F. O'Dowd

Agonist-independent Nuclear Localization of the Apelin, Angiotensin AT₁, and Bradykinin B₂ Receptors
J. Biol. Chem. 2004 279: 7901-7908. First Published on November 26, 2003; doi:10.1074/jbc.M306377200 [Abstract] [Full Text] [PDF]  

Tom Vanden Berghe, Geert van Loo, Xavier Saelens, Maria van Gurp, Greet Brouckaert, Michael Kalai, Wim Declercq, and Peter Vandenabeele

Differential Signaling to Apoptotic and Necrotic Cell Death by Fas-associated Death Domain Protein FADD
J. Biol. Chem. 2004 279: 7925-7933. First Published on December 10, 2003; doi:10.1074/jbc.M307807200 [Abstract] [Full Text] [PDF]  

Tadao Shibasaki, Yasuhiro Sunaga, Kei Fujimoto, Yasushige Kashima, and Susumu Seino

Interaction of ATP Sensor, cAMP Sensor, Ca²⁺ Sensor, and Voltage-dependent Ca²⁺ Channel in Insulin Granule Exocytosis
J. Biol. Chem. 2004 279: 7956-7961. First Published on December 3, 2003; doi:10.1074/jbc.M309068200 [Abstract] [Full Text] [PDF]  

Ok-Jin Kim, Benjamin R. Gardner, Daniel B. Williams, Paul S. Marinec, David M. Cabrera, Jennifer D. Peters, Chun C. Mak, Kyeong-Man Kim, and David R. Sibley

The Role of Phosphorylation in D₁ Dopamine Receptor Desensitization: EVIDENCE FOR A NOVEL MECHANISM OF ARRESTIN ASSOCIATION
J. Biol. Chem. 2004 279: 7999-8010. First Published on December 4, 2003; doi:10.1074/jbc.M308281200 [Abstract] [Full Text] [PDF] Supplemental Data  

Philippe Sarret, M. James Esdaile, Peter S. McPherson, Agnes Schonbrunn, Hans-Jürgen Kreienkamp, and Alain Beaudet

Role of Amphiphysin II in Somatostatin Receptor Trafficking in Neuroendocrine Cells
J. Biol. Chem. 2004 279: 8029-8037. First Published on December 3, 2003; doi:10.1074/jbc.M310792200 [Abstract] [Full Text] [PDF]  

Yi Wang, Steven D. Pennock, Xinmei Chen, Andrius Kazlauskas, and Zhixiang Wang

Platelet-derived Growth Factor Receptor-mediated Signal Transduction from Endosomes
J. Biol. Chem. 2004 279: 8038-8046. First Published on December 2, 2003; doi:10.1074/jbc.M311494200 [Abstract] [Full Text] [PDF]  

Oleh V. Stasyk, Olena G. Stasyk, Janet Komduur, Marten Veenhuis, James M. Cregg, and Andrei A. Sibirny

A Hexose Transporter Homologue Controls Glucose Repression in the Methylotrophic Yeast Hansenula polymorpha
J. Biol. Chem. 2004 279: 8116-8125. First Published on December 3, 2003; doi:10.1074/jbc.M310960200 [Abstract] [Full Text] [PDF]  

Srinivasan Madabushi, Alecia K. Gross, Anne Philippi, Elaine C. Meng, Theodore G. Wensel, and Olivier Lichtarge

Evolutionary Trace of G Protein-coupled Receptors Reveals Clusters of Residues That Determine Global and Class-specific Functions
J. Biol. Chem. 2004 279: 8126-8132. First Published on December 5, 2003; doi:10.1074/jbc.M312671200 [Abstract] [Full Text] [PDF] Supplemental Data  

Kate E. Broderick, Laura Kean, Julian A. T. Dow, Nigel J. Pyne, and Shireen A. Davies

Ectopic Expression of Bovine Type 5 Phosphodiesterase Confers a Renal Phenotype in Drosophila
J. Biol. Chem. 2004 279: 8159-8168. First Published on December 8, 2003; doi:10.1074/jbc.M304679200 [Abstract] [Full Text] [PDF]  

Steven J. Cok, Stephen J. Acton, Alison E. Sexton, and Aubrey R. Morrison

Identification of RNA-binding Proteins in RAW 264.7 Cells That Recognize a Lipopolysaccharide-responsive Element in the 3-Untranslated Region of the Murine Cyclooxygenase-2 mRNA
J. Biol. Chem. 2004 279: 8196-8205. First Published on December 8, 2003; doi:10.1074/jbc.M308475200 [Abstract] [Full Text] [PDF]  

Jun Liu, Zhongji Liao, Jean Camden, Korey D. Griffin, Richard C. Garrad, Laura I. Santiago-Pérez, Fernando A. González, Cheikh I. Seye, Gary A. Weisman, and Laurie Erb

Src Homology 3 Binding Sites in the P2Y₂ Nucleotide Receptor Interact with Src and Regulate Activities of Src, Proline-rich Tyrosine Kinase 2, and Growth Factor Receptors
J. Biol. Chem. 2004 279: 8212-8218. First Published on December 11, 2003; doi:10.1074/jbc.M312230200 [Abstract] [Full Text] [PDF]  

Fernando C. Gómez-Merino, Charles A. Brearley, Magdalena Ornatowska, Mahmoud E. F. Abdel-Haliem, María-Inés Zanor, and Bernd Mueller-Roeber

AtDGK2, a Novel Diacylglycerol Kinase from Arabidopsis thaliana, Phosphorylates 1-Stearoyl-2-arachidonoyl-sn-glycerol and 1,2-Dioleoyl-sn-glycerol and Exhibits Cold-inducible Gene Expression
J. Biol. Chem. 2004 279: 8230-8241. First Published on December 9, 2003; doi:10.1074/jbc.M312187200 [Abstract] [Full Text] [PDF]  

Xin Cheng, Masa Kinosaki, Masamichi Takami, Yongwon Choi, Hongtao Zhang, and Ramachandran Murali

Disabling of Receptor Activator of Nuclear Factor-B (RANK) Receptor Complex by Novel Osteoprotegerin-like Peptidomimetics Restores Bone Loss in Vivo
J. Biol. Chem. 2004 279: 8269-8277. First Published on December 15, 2003; doi:10.1074/jbc.M309690200 [Abstract] [Full Text] [PDF]  

Wook Kim, Seunghyi Kook, Dae Joong Kim, Carmen Teodorof, and Woo Keun Song

The 31-kDa Caspase-generated Cleavage Product of p130^cas Functions as a Transcriptional Repressor of E2A in Apoptotic Cells
J. Biol. Chem. 2004 279: 8333-8342. First Published on December 2, 2003; doi:10.1074/jbc.M312026200 [Abstract] [Full Text] [PDF]  

Takeshi Sekiguchi, Yuko Todaka, Yonggang Wang, Eiji Hirose, Nobutaka Nakashima, and Takeharu Nishimoto

A Novel Human Nucleolar Protein, Nop132, Binds to the G Proteins, RRAG A/C/D
J. Biol. Chem. 2004 279: 8343-8350. First Published on December 4, 2003; doi:10.1074/jbc.M305935200 [Abstract] [Full Text] [PDF]  

John G. McCarron, Debbi MacMillan, Karen N. Bradley, Susan Chalmers, and Thomas C. Muir

Origin and Mechanisms of Ca²⁺ Waves in Smooth Muscle as Revealed by Localized Photolysis of Caged Inositol 1,4,5-Trisphosphate
J. Biol. Chem. 2004 279: 8417-8427. First Published on December 4, 2003; doi:10.1074/jbc.M311797200 [Abstract] [Full Text] [PDF] Supplemental Data  

Susanna Grundström, Per Anderson, Peter Scheipers, and Anette Sundstedt

Bcl-3 and NFB p50-p50 Homodimers Act as Transcriptional Repressors in Tolerant CD4⁺ T Cells
J. Biol. Chem. 2004 279: 8460-8468. First Published on December 10, 2003; doi:10.1074/jbc.M312398200 [Abstract] [Full Text] [PDF]  

Yuan Ren, Songshu Meng, Lin Mei, Z. Joe Zhao, Richard Jove, and Jie Wu

Roles of Gab1 and SHP2 in Paxillin Tyrosine Dephosphorylation and Src Activation in Response to Epidermal Growth Factor
J. Biol. Chem. 2004 279: 8497-8505. First Published on December 8, 2003; doi:10.1074/jbc.M312575200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Gabriela Velasco-Loyden, Joaquín Arribas, and Fernando López-Casillas

The Shedding of Betaglycan Is Regulated by Pervanadate and Mediated by Membrane Type Matrix Metalloprotease-1
J. Biol. Chem. 2004 279: 7721-7733. First Published on December 12, 2003; doi:10.1074/jbc.M306499200 [Abstract] [Full Text] [PDF]  

Jean-François Mouillet, Christina Sonnenberg-Hirche, Xiaomei Yan, and Yoel Sadovsky

p300 Regulates the Synergy of Steroidogenic Factor-1 and Early Growth Response-1 in Activating Luteinizing Hormone- Subunit Gene
J. Biol. Chem. 2004 279: 7832-7839. First Published on December 17, 2003; doi:10.1074/jbc.M312574200 [Abstract] [Full Text] [PDF]  

Pavan K. Krishnamurthy and Gail V. W. Johnson

Mutant (R406W) Human Tau Is Hyperphosphorylated and Does Not Efficiently Bind Microtubules in a Neuronal Cortical Cell Model
J. Biol. Chem. 2004 279: 7893-7900. First Published on December 2, 2003; doi:10.1074/jbc.M311203200 [Abstract] [Full Text] [PDF]  

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Additions and Corrections:

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