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Table of Contents: Jan 7 2005; 280 (1)   [Index by Author]  [Papers Of The Week]
[Cover Figure and Caption]
       Papers Of The Week
       Minireviews
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Genomics, Proteomics, and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Papers Of The Week:

A Mechanism for Osteoarthritis
J. Biol. Chem. 2005 280: e99901. [Full Text] [PDF]  


Minireviews:

Franz Hofmann
The Biology of Cyclic GMP-dependent Protein Kinases
J. Biol. Chem. 2005 280: 1-4. First Published on November 15, 2004; doi:10.1074/jbc.R400035200 [Full Text] [PDF]  


Accelerated Publications:

Anita Öst, Unn Örtegren, Johanna Gustavsson, Fredrik H. Nystrom, and Peter Strålfors
Triacylglycerol Is Synthesized in a Specific Subclass of Caveolae in Primary Adipocytes
J. Biol. Chem. 2005 280: 5-8. First Published on November 9, 2004; doi:10.1074/jbc.C400429200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:

Giedrius Vilkaitis, Isao Suetake, Saulius Klimasauskas, and Shoji Tajima
Processive Methylation of Hemimethylated CpG Sites by Mouse Dnmt1 DNA Methyltransferase
J. Biol. Chem. 2005 280: 64-72. First Published on October 27, 2004; doi:10.1074/jbc.M411126200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Vera A. Stupina and James C. Wang
Viability of Escherichia coli topA Mutants Lacking DNA Topoisomerase I
J. Biol. Chem. 2005 280: 355-360. First Published on November 1, 2004; doi:10.1074/jbc.M411924200 [Abstract] [Full Text] [PDF]  

Cheryll Perry, Renuka Sastry, Ilya M. Nasrallah, and Patrick J. Stover
Mimosine Attenuates Serine Hydroxymethyltransferase Transcription by Chelating Zinc: IMPLICATIONS FOR INHIBITION OF DNA REPLICATION
J. Biol. Chem. 2005 280: 396-400. First Published on November 4, 2004; doi:10.1074/jbc.M410467200 [Abstract] [Full Text] [PDF]  

Dau-Yin Chang and A-Lien Lu
Interaction of Checkpoint Proteins Hus1/Rad1/Rad9 with DNA Base Excision Repair Enzyme MutY Homolog in Fission Yeast, Schizosaccharomyces pombe
J. Biol. Chem. 2005 280: 408-417. First Published on November 8, 2004; doi:10.1074/jbc.M406800200 [Abstract] [Full Text] [PDF]  

Hui Zhu and Stewart Shuman
A Primer-dependent Polymerase Function of Pseudomonas aeruginosa ATP-dependent DNA Ligase (LigD)
J. Biol. Chem. 2005 280: 418-427. First Published on October 31, 2004; doi:10.1074/jbc.M410110200 [Abstract] [Full Text] [PDF]  

Yan Wu, Xinguo Qian, Yujiong He, Ignace A. Moya, and Yu Luo
Crystal Structure of an ATPase-active Form of Rad51 Homolog from Methanococcus voltae: INSIGHTS INTO POTASSIUM DEPENDENCE
J. Biol. Chem. 2005 280: 722-728. First Published on November 10, 2004; doi:10.1074/jbc.M411093200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Hui-Ching Kuo, John D. Moore, and Jocelyn E. Krebs
Histone H2A and Spt10 Cooperate to Regulate Induction and Autoregulation of the CUP1 Metallothionein
J. Biol. Chem. 2005 280: 104-111. First Published on October 21, 2004; doi:10.1074/jbc.M411437200 [Abstract] [Full Text] [PDF]  

Alexandre Bobard, Isabelle Hainault, Pascal Ferré, Fabienne Foufelle, and Pascale Bossard
Differential Regulation of Sterol Regulatory Element-binding Protein 1c Transcriptional Activity by Insulin and Liver X Receptor during Liver Development
J. Biol. Chem. 2005 280: 199-206. First Published on October 27, 2004; doi:10.1074/jbc.M406522200 [Abstract] [Full Text] [PDF]  

Josef Anrather, Gianfranco Racchumi, and Costantino Iadecola
cis-Acting Element-specific Transcriptional Activity of Differentially Phosphorylated Nuclear Factor-{kappa}B
J. Biol. Chem. 2005 280: 244-252. First Published on October 29, 2004; doi:10.1074/jbc.M409344200 [Abstract] [Full Text] [PDF]  

Keikantse Matlhagela, Maryann Borsick, Trivikram Rajkhowa, and Mary Taub
Identification of a Prostaglandin-responsive Element in the Na,K-ATPase {beta}1 Promoter That Is Regulated by cAMP and Ca2+: EVIDENCE FOR AN INTERACTIVE ROLE OF cAMP REGULATORY ELEMENT-BINDING PROTEIN AND Sp1
J. Biol. Chem. 2005 280: 334-346. First Published on October 14, 2004; doi:10.1074/jbc.M411415200 [Abstract] [Full Text] [PDF]  

Jennifer R. Schultz, Larry N. Petz, and Ann M. Nardulli
Cell- and Ligand-specific Regulation of Promoters Containing Activator Protein-1 and Sp1 Sites by Estrogen Receptors {alpha} and {beta}
J. Biol. Chem. 2005 280: 347-354. First Published on October 26, 2004; doi:10.1074/jbc.M407879200 [Abstract] [Full Text] [PDF]  

Valérie Plaisance, Guy Niederhauser, Fayçal Azzouz, Vincent Lenain, Jacques-Antoine Haefliger, Gérard Waeber, and Amar Abderrahmani
The Repressor Element Silencing Transcription Factor (REST)-mediated Transcriptional Repression Requires the Inhibition of Sp1
J. Biol. Chem. 2005 280: 401-407. First Published on November 4, 2004; doi:10.1074/jbc.M411825200 [Abstract] [Full Text] [PDF]  

Silvia Buonamici, Donglan Li, Fady M. Mikhail, Antonella Sassano, Leonidas C. Platanias, Oscar Colamonici, John Anastasi, and Giuseppina Nucifora
EVI1 Abrogates Interferon-{alpha} Response by Selectively Blocking PML Induction
J. Biol. Chem. 2005 280: 428-436. First Published on November 1, 2004; doi:10.1074/jbc.M410836200 [Abstract] [Full Text] [PDF]  

Marianne Parent, Tetsu M. C. Yung, Ann Rancourt, Erick L. Y. Ho, Stéphane Vispé, Fumihiko Suzuki-Matsuda, Aki Uehara, Tadashi Wada, Hiroshi Handa, and Masahiko S. Satoh
Poly(ADP-ribose) Polymerase-1 Is a Negative Regulator of HIV-1 Transcription through Competitive Binding to TAR RNA with Tat·Positive Transcription Elongation Factor b (p-TEFb) Complex
J. Biol. Chem. 2005 280: 448-457. First Published on October 21, 2004; doi:10.1074/jbc.M408435200 [Abstract] [Full Text] [PDF]  

Gabriella Gardian, Susan E. Browne, Dong-Kug Choi, Peter Klivenyi, Jason Gregorio, James K. Kubilus, Hoon Ryu, Brett Langley, Rajiv R. Ratan, Robert J. Ferrante, and M. Flint Beal
Neuroprotective Effects of Phenylbutyrate in the N171-82Q Transgenic Mouse Model of Huntington's Disease
J. Biol. Chem. 2005 280: 556-563. First Published on October 19, 2004; doi:10.1074/jbc.M410210200 [Abstract] [Full Text] [PDF]  

Andreas Krug, Volker F. Wendisch, and Michael Bott
Identification of AcnR, a TetR-type Repressor of the Aconitase Gene acn in Corynebacterium glutamicum
J. Biol. Chem. 2005 280: 585-595. First Published on October 19, 2004; doi:10.1074/jbc.M408271200 [Abstract] [Full Text] [PDF]  

Jong-So Kim, Steven L. Coon, Seth Blackshaw, Constance L. Cepko, Morten Møller, Sujira Mukda, Wan-Qian Zhao, Clivel G. Charlton, and David C. Klein
Methionine Adenosyltransferase:Adrenergic-cAMP Mechanism Regulates a Daily Rhythm in Pineal Expression
J. Biol. Chem. 2005 280: 677-684. First Published on October 25, 2004; doi:10.1074/jbc.M408438200 [Abstract] [Full Text] [PDF]  

Shuang Chang and Craig S. Pikaard
Transcript Profiling in Arabidopsis Reveals Complex Responses to Global Inhibition of DNA Methylation and Histone Deacetylation
J. Biol. Chem. 2005 280: 796-804. First Published on October 29, 2004; doi:10.1074/jbc.M409053200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


RNA: Structure, Metabolism, and Catalysis:

Wei-Wen Ge, Weiyan Wen, Wendy Strong, Cheryl Leystra-Lantz, and Michael J. Strong
Mutant Copper-Zinc Superoxide Dismutase Binds to and Destabilizes Human Low Molecular Weight Neurofilament mRNA
J. Biol. Chem. 2005 280: 118-124. First Published on October 25, 2004; doi:10.1074/jbc.M405065200 [Abstract] [Full Text] [PDF]  

Zifan Lu, Li Ku, Yuntao Chen, and Yue Feng
Developmental Abnormalities of Myelin Basic Protein Expression in fyn Knock-out Brain Reveal a Role of Fyn in Posttranscriptional Regulation
J. Biol. Chem. 2005 280: 389-395. First Published on November 4, 2004; doi:10.1074/jbc.M405973200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:

Arlo J. Miller, Carmit Levy, Ian J. Davis, Ehud Razin, and David E. Fisher
Sumoylation of MITF and Its Related Family Members TFE3 and TFEB
J. Biol. Chem. 2005 280: 146-155. First Published on October 25, 2004; doi:10.1074/jbc.M411757200 [Abstract] [Full Text] [PDF]  

Jason A. Rosenzweig, Gabriela Weltman, Gregory V. Plano, and Kurt Schesser
Modulation of Yersinia Type Three Secretion System by the S1 Domain of Polynucleotide Phosphorylase
J. Biol. Chem. 2005 280: 156-163. First Published on October 26, 2004; doi:10.1074/jbc.M405662200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Xiao-Bo Qiu and Alfred L. Goldberg
The Membrane-associated Inhibitor of Apoptosis Protein, BRUCE/Apollon, Antagonizes Both the Precursor and Mature Forms of Smac and Caspase-9
J. Biol. Chem. 2005 280: 174-182. First Published on October 26, 2004; doi:10.1074/jbc.M411430200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Xinhe Wang, Fei Wang, Man-Sun Sy, and Jiyan Ma
Calpain and Other Cytosolic Proteases Can Contribute to the Degradation of Retro-translocated Prion Protein in the Cytosol
J. Biol. Chem. 2005 280: 317-325. First Published on November 2, 2004; doi:10.1074/jbc.M410649200 [Abstract] [Full Text] [PDF]  

Hiroaki Takeuchi, Sandra Kao, Eri Miyagi, Mohammad A. Khan, Alicia Buckler-White, Ron Plishka, and Klaus Strebel
Production of Infectious SIVagm from Human Cells Requires Functional Inactivation but Not Viral Exclusion of Human APOBEC3G
J. Biol. Chem. 2005 280: 375-382. First Published on November 3, 2004; doi:10.1074/jbc.M408987200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Shiho Miyase, Satoshi Tateishi, Kenji Watanabe, Kimio Tomita, Keiichiro Suzuki, Hirokazu Inoue, and Masaru Yamaizumi
Differential Regulation of Rad18 through Rad6-dependent Mono- and Polyubiquitination
J. Biol. Chem. 2005 280: 515-524. First Published on October 27, 2004; doi:10.1074/jbc.M409219200 [Abstract] [Full Text] [PDF]  

Virginie Redeker, Nicolette Levilliers, Emilie Vinolo, Jean Rossier, Danielle Jaillard, Dylan Burnette, Jacek Gaertig, and Marie-Hélène Bré
Mutations of Tubulin Glycylation Sites Reveal Cross-talk between the C Termini of {alpha}- and {beta}-Tubulin and Affect the Ciliary Matrix in Tetrahymena
J. Biol. Chem. 2005 280: 596-606. First Published on October 18, 2004; doi:10.1074/jbc.M408324200 [Abstract] [Full Text] [PDF]  

Alessio Cardinale, Ilaria Filesi, Vito Vetrugno, Maurizio Pocchiari, Man-Sun Sy, and Silvia Biocca
Trapping Prion Protein in the Endoplasmic Reticulum Impairs PrPC Maturation and Prevents PrPSc Accumulation
J. Biol. Chem. 2005 280: 685-694. First Published on October 28, 2004; doi:10.1074/jbc.M407360200 [Abstract] [Full Text] [PDF]  

Tatiana A. Soboleva, David A. Jans, Melanie Johnson-Saliba, and Rohan T. Baker
Nuclear-Cytoplasmic Shuttling of the Oncogenic Mouse UNP/USP4 Deubiquitylating Enzyme
J. Biol. Chem. 2005 280: 745-752. First Published on October 18, 2004; doi:10.1074/jbc.M401394200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:

Jolanta Zaim, Elzbieta Speina, and Andrzej M. Kierzek
Identification of New Genes Regulated by the Crt1 Transcription Factor, an Effector of the DNA Damage Checkpoint Pathway in Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 28-37. First Published on October 19, 2004; doi:10.1074/jbc.M404669200 [Abstract] [Full Text] [PDF]  

Siew Leng Tai, Viktor M. Boer, Pascale Daran-Lapujade, Michael C. Walsh, Johannes H. de Winde, Jean-Marc Daran, and Jack T. Pronk
Two-dimensional Transcriptome Analysis in Chemostat Cultures: COMBINATORIAL EFFECTS OF OXYGEN AVAILABILITY AND MACRONUTRIENT LIMITATION IN SACCHAROMYCES CEREVISIAE
J. Biol. Chem. 2005 280: 437-447. First Published on October 20, 2004; doi:10.1074/jbc.M410573200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Protein Structure and Folding:

Naveen K. Dakappagari, Kenneth D. Lute, Sharad Rawale, Joan T. Steele, Stephanie D. Allen, Gary Phillips, R. Todd Reilly, and Pravin T. P. Kaumaya
Conformational HER-2/neu B-cell Epitope Peptide Vaccine Designed to Incorporate Two Native Disulfide Bonds Enhances Tumor Cell Binding and Antitumor Activities
J. Biol. Chem. 2005 280: 54-63. First Published on October 26, 2004; doi:10.1074/jbc.M411020200 [Abstract] [Full Text] [PDF]  

Layla Azam, Cheryl Dowell, Maren Watkins, Jerry A. Stitzel, Baldomero M. Olivera, and J. Michael McIntosh
{alpha}-Conotoxin BuIA, a Novel Peptide from Conus bullatus, Distinguishes among Neuronal Nicotinic Acetylcholine Receptors
J. Biol. Chem. 2005 280: 80-87. First Published on November 1, 2004; doi:10.1074/jbc.M406281200 [Abstract] [Full Text] [PDF]  

Shuai Chen, Lili Chen, Jinzhi Tan, Jing Chen, Li Du, Tao Sun, Jianhua Shen, Kaixian Chen, Hualiang Jiang, and Xu Shen
Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase N Terminus Is Indispensable for Proteolytic Activity but Not for Enzyme Dimerization: BIOCHEMICAL AND THERMODYNAMIC INVESTIGATION IN CONJUNCTION WITH MOLECULAR DYNAMICS SIMULATIONS
J. Biol. Chem. 2005 280: 164-173. First Published on October 26, 2004; doi:10.1074/jbc.M408211200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Zhi-Ren Zhang, Guiying Cui, Xuehong Liu, Binlin Song, David C. Dawson, and Nael A. McCarty
Determination of the Functional Unit of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel: ONE POLYPEPTIDE FORMS ONE PORE
J. Biol. Chem. 2005 280: 458-468. First Published on October 25, 2004; doi:10.1074/jbc.M409626200 [Abstract] [Full Text] [PDF]  

Leonard M. G. Chavas, Cristina Tringali, Paola Fusi, Bruno Venerando, Guido Tettamanti, Ryuichi Kato, Eugenio Monti, and Soichi Wakatsuki
Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
J. Biol. Chem. 2005 280: 469-475. First Published on October 22, 2004; doi:10.1074/jbc.M411506200 [Abstract] [Full Text] [PDF]  

Daniel A. Breustedt, Ingo P. Korndörfer, Bernhard Redl, and Arne Skerra
The 1.8-Å Crystal Structure of Human Tear Lipocalin Reveals an Extended Branched Cavity with Capacity for Multiple Ligands
J. Biol. Chem. 2005 280: 484-493. First Published on October 15, 2004; doi:10.1074/jbc.M410466200 [Abstract] [Full Text] [PDF]  

Alicia Lammerts van Bueren, Carl Morland, Harry J. Gilbert, and Alisdair B. Boraston
Family 6 Carbohydrate Binding Modules Recognize the Non-reducing End of {beta}-1,3-Linked Glucans by Presenting a Unique Ligand Binding Surface
J. Biol. Chem. 2005 280: 530-537. First Published on October 22, 2004; doi:10.1074/jbc.M410113200 [Abstract] [Full Text] [PDF]  

Subhradip Mukhopadhyay, Knut Langsetmo, Walter F. Stafford, III, Gillian D. Henry, James D. Baleja, and Satyapriya Sarkar
Identification of a Region of Fast Skeletal Troponin T Required for Stabilization of the Coiled-coil Formation with Troponin I
J. Biol. Chem. 2005 280: 538-547. First Published on October 26, 2004; doi:10.1074/jbc.M409537200 [Abstract] [Full Text] [PDF]  

Mitchell Ho, Robert J. Kreitman, Masanori Onda, and Ira Pastan
In Vitro Antibody Evolution Targeting Germline Hot Spots to Increase Activity of an Anti-CD22 Immunotoxin
J. Biol. Chem. 2005 280: 607-617. First Published on October 18, 2004; doi:10.1074/jbc.M409783200 [Abstract] [Full Text] [PDF]  

Chun-Yang Fan, Hong-Yu Ren, Paul Lee, Avrom J. Caplan, and Douglas M. Cyr
The Type I Hsp40 Zinc Finger-like Region Is Required for Hsp70 to Capture Non-native Polypeptides from Ydj1
J. Biol. Chem. 2005 280: 695-702. First Published on October 20, 2004; doi:10.1074/jbc.M410645200 [Abstract] [Full Text] [PDF]  

Gerwald Jogl, Yu-Shan Hsiao, and Liang Tong
Crystal Structure of Mouse Carnitine Octanoyltransferase and Molecular Determinants of Substrate Selectivity
J. Biol. Chem. 2005 280: 738-744. First Published on October 17, 2004; doi:10.1074/jbc.M409894200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Enzyme Catalysis and Regulation:

Nikki A. Copeland and Colin Kleanthous
The Role of an Activating Peptide in Protease-mediated Suicide of Escherichia coli K12
J. Biol. Chem. 2005 280: 112-117. First Published on October 22, 2004; doi:10.1074/jbc.M411280200 [Abstract] [Full Text] [PDF]  

Ayelet Fishman, Ying Tao, Lingyun Rui, and Thomas K. Wood
Controlling the Regiospecific Oxidation of Aromatics via Active Site Engineering of Toluene para-Monooxygenase of Ralstonia pickettii PKO1
J. Biol. Chem. 2005 280: 506-514. First Published on October 21, 2004; doi:10.1074/jbc.M410320200 [Abstract] [Full Text] [PDF]  

Susan E. Akerman and Sylke Müller
Peroxiredoxin-linked Detoxification of Hydroperoxides in Toxoplasma gondii
J. Biol. Chem. 2005 280: 564-570. First Published on October 26, 2004; doi:10.1074/jbc.M406367200 [Abstract] [Full Text] [PDF]  

Benfang Ruan, Michael L. Bovee, Meik Sacher, Constantinos Stathopoulos, Karl Poralla, Christopher S. Francklyn, and Dieter Söll
A Unique Hydrophobic Cluster Near the Active Site Contributes to Differences in Borrelidin Inhibition among Threonyl-tRNA Synthetases
J. Biol. Chem. 2005 280: 571-577. First Published on October 26, 2004; doi:10.1074/jbc.M411039200 [Abstract] [Full Text] [PDF]  

Yuichiro Higashimoto, Hiroshi Sakamoto, Shunsuke Hayashi, Masakazu Sugishima, Keiichi Fukuyama, Graham Palmer, and Masato Noguchi
Involvement of NADP(H) in the Interaction between Heme Oxygenase-1 and Cytochrome P450 Reductase
J. Biol. Chem. 2005 280: 729-737. First Published on October 31, 2004; doi:10.1074/jbc.M406203200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Judith Y. Altarejos, Masayuki Taniguchi, Alexander S. Clanachan, and Gary D. Lopaschuk
Myocardial Ischemia Differentially Regulates LKB1 and an Alternate 5'-AMP-activated Protein Kinase Kinase
J. Biol. Chem. 2005 280: 183-190. First Published on October 26, 2004; doi:10.1074/jbc.M411810200 [Abstract] [Full Text] [PDF]  

Eiko Nakamaru-Ogiso, Takahiro Yano, Takao Yagi, and Tomoko Ohnishi
Characterization of the Iron-Sulfur Cluster N7 (N1c) in the Subunit NuoG of the Proton-translocating NADH-quinone Oxidoreductase from Escherichia coli
J. Biol. Chem. 2005 280: 301-307. First Published on November 1, 2004; doi:10.1074/jbc.M410377200 [Abstract] [Full Text] [PDF]  

Sergej L. Mironov, Maxim V. Ivannikov, and Mattias Johansson
[Ca2+]i Signaling between Mitochondria and Endoplasmic Reticulum in Neurons Is Regulated by Microtubules: FROM MITOCHONDRIAL PERMEABILITY TRANSITION PORE TO Ca2+-INDUCED Ca2+ RELEASE
J. Biol. Chem. 2005 280: 715-721. First Published on October 29, 2004; doi:10.1074/jbc.M409819200 [Abstract] [Full Text] [PDF]  

Naomi Hosoya-Matsuda, Ken Motohashi, Hidehisa Yoshimura, Akiko Nozaki, Kazuhito Inoue, Masayuki Ohmori, and Toru Hisabori
Anti-oxidative Stress System in Cyanobacteria: SIGNIFICANCE OF TYPE II PEROXIREDOXIN AND THE ROLE OF 1-Cys PEROXIREDOXIN IN SYNECHOCYSTIS SP. STRAIN PCC 6803
J. Biol. Chem. 2005 280: 840-846. First Published on October 27, 2004; doi:10.1074/jbc.M411493200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Colin P. Johnson, Ichiro Fujimoto, Urs Rutishauser, and Deborah E. Leckband
Direct Evidence That Neural Cell Adhesion Molecule (NCAM) Polysialylation Increases Intermembrane Repulsion and Abrogates Adhesion
J. Biol. Chem. 2005 280: 137-145. First Published on October 25, 2004; doi:10.1074/jbc.M410216200 [Abstract] [Full Text] [PDF]  

Raymond Brittingham, Morgana Colombo, Hidetoshi Ito, Andrzej Steplewski, David E. Birk, Jouni Uitto, and Andrzej Fertala
Single Amino Acid Substitutions in Procollagen VII Affect Early Stages of Assembly of Anchoring Fibrils
J. Biol. Chem. 2005 280: 191-198. First Published on October 27, 2004; doi:10.1074/jbc.M406210200 [Abstract] [Full Text] [PDF]  

Jon B. Raymond, Sebabrata Mahapatra, Dean C. Crick, and Martin S. Pavelka, Jr.
Identification of the namH Gene, Encoding the Hydroxylase Responsible for the N-Glycolylation of the Mycobacterial Peptidoglycan
J. Biol. Chem. 2005 280: 326-333. First Published on November 2, 2004; doi:10.1074/jbc.M411006200 [Abstract] [Full Text] [PDF]  

Mark S. Pankonin, John T. Gallagher, and Jeffrey A. Loeb
Specific Structural Features of Heparan Sulfate Proteoglycans Potentiate Neuregulin-1 Signaling
J. Biol. Chem. 2005 280: 383-388. First Published on November 4, 2004; doi:10.1074/jbc.M402645200 [Abstract] [Full Text] [PDF]  

Ho Jun Lee, Christopher H. Barry, Svetlana N. Borisova, Nina O. L. Seto, Ruixiang Blake Zheng, Antoine Blancher, Stephen V. Evans, and Monica M. Palcic
Structural Basis for the Inactivity of Human Blood Group O2 Glycosyltransferase
J. Biol. Chem. 2005 280: 525-529. First Published on October 8, 2004; doi:10.1074/jbc.M410245200 [Abstract] [Full Text] [PDF]  

Lin Xu, Haibing Peng, Dongying Wu, Kenpan Hu, Mary B. Goldring, Bjorn R. Olsen, and Yefu Li
Activation of the Discoidin Domain Receptor 2 Induces Expression of Matrix Metalloproteinase 13 Associated with Osteoarthritis in Mice
J. Biol. Chem. 2005 280: 548-555. First Published on October 27, 2004; doi:10.1074/jbc.M411036200 [Abstract] [Full Text] [PDF] [Summary]  


Lipids and Lipoproteins:

Surapon Piboonpocanun, Hirofumi Chiba, Hiroaki Mitsuzawa, Wesley Martin, Robert C. Murphy, Ronald J. Harbeck, and Dennis R. Voelker
Surfactant Protein A Binds Mycoplasma pneumoniae with High Affinity and Attenuates Its Growth by Recognition of Disaturated Phosphatidylglycerols
J. Biol. Chem. 2005 280: 9-17. First Published on October 21, 2004; doi:10.1074/jbc.M411570200 [Abstract] [Full Text] [PDF]  

Lemin Zheng, Megan Settle, Gregory Brubaker, Dave Schmitt, Stanley L. Hazen, Jonathan D. Smith, and Michael Kinter
Localization of Nitration and Chlorination Sites on Apolipoprotein A-I Catalyzed by Myeloperoxidase in Human Atheroma and Associated Oxidative Impairment in ABCA1-dependent Cholesterol Efflux from Macrophages
J. Biol. Chem. 2005 280: 38-47. First Published on October 21, 2004; doi:10.1074/jbc.M407019200 [Abstract] [Full Text] [PDF]  

Qiwei Zhang, Michael D. Southall, Steven M. Mezsick, Christopher Johnson, Robert C. Murphy, Raymond L. Konger, and Jeffrey B. Travers
Epidermal Peroxisome Proliferator-activated Receptor {gamma} as a Target for Ultraviolet B Radiation
J. Biol. Chem. 2005 280: 73-79. First Published on October 29, 2004; doi:10.1074/jbc.M409795200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:

Uwe Ahting, Thomas Waizenegger, Walter Neupert, and Doron Rapaport
Signal-anchored Proteins Follow a Unique Insertion Pathway into the Outer Membrane of Mitochondria
J. Biol. Chem. 2005 280: 48-53. First Published on October 22, 2004; doi:10.1074/jbc.M410905200 [Abstract] [Full Text] [PDF]  

Shun-ichi Wada, Koichi Tanabe, Akiko Yamazaki, Masakazu Niimi, Yoshimasa Uehara, Kyoko Niimi, Erwin Lamping, Richard D. Cannon, and Brian C. Monk
Phosphorylation of Candida glabrata ATP-binding Cassette Transporter Cdr1p Regulates Drug Efflux Activity and ATPase Stability
J. Biol. Chem. 2005 280: 94-103. First Published on October 21, 2004; doi:10.1074/jbc.M408252200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Lin Yang, Guoxia Liu, Sergey I. Zakharov, John P. Morrow, Vitali O. Rybin, Susan F. Steinberg, and Steven O. Marx
Ser1928 Is a Common Site for Cav1.2 Phosphorylation by Protein Kinase C Isoforms
J. Biol. Chem. 2005 280: 207-214. First Published on October 27, 2004; doi:10.1074/jbc.M410509200 [Abstract] [Full Text] [PDF]  

Kenton Ko, Darcie Taylor, Paulo Argenton, Jennette Innes, Babak Pedram, Fabian Seibert, Antonio Granell, and Zdenka Ko
Evidence That the Plastid Translocon Tic40 Components Possess Modulating Capabilities
J. Biol. Chem. 2005 280: 215-224. First Published on October 28, 2004; doi:10.1074/jbc.M410088200 [Abstract] [Full Text] [PDF]  

Umesh Ahuja and Linda Thöny-Meyer
CcmD Is Involved in Complex Formation between CcmC and the Heme Chaperone CcmE during Cytochrome c Maturation
J. Biol. Chem. 2005 280: 236-243. First Published on October 28, 2004; doi:10.1074/jbc.M410912200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Teresa M. Buck and William R. Skach
Differential Stability of Biogenesis Intermediates Reveals a Common Pathway for Aquaporin-1 Topological Maturation
J. Biol. Chem. 2005 280: 261-269. First Published on October 28, 2004; doi:10.1074/jbc.M409920200 [Abstract] [Full Text] [PDF]  

Laurent Berrou, Yolaine Dodier, Alexandra Raybaud, Audrey Tousignant, Omar Dafi, Joelle N. Pelletier, and Lucie Parent
The C-terminal Residues in the Alpha-interacting Domain (AID) Helix Anchor CaV{beta} Subunit Interaction and Modulation of CaV2.3 Channels
J. Biol. Chem. 2005 280: 494-505. First Published on October 26, 2004; doi:10.1074/jbc.M410859200 [Abstract] [Full Text] [PDF]  

Scott W. Eastman, Juan Martin-Serrano, Wayne Chung, Trinity Zang, and Paul D. Bieniasz
Identification of Human VPS37C, a Component of Endosomal Sorting Complex Required for Transport-I Important for Viral Budding
J. Biol. Chem. 2005 280: 628-636. First Published on October 27, 2004; doi:10.1074/jbc.M410384200 [Abstract] [Full Text] [PDF]  

Tomoyuki Suzuki, Kaori Ishihara, Hitoshi Migaki, Wataru Matsuura, Atsushi Kohda, Katsuzumi Okumura, Masaya Nagao, Yuko Yamaguchi-Iwai, and Taiho Kambe
Zinc Transporters, ZnT5 and ZnT7, Are Required for the Activation of Alkaline Phosphatases, Zinc-requiring Enzymes That Are Glycosylphosphatidylinositol-anchored to the Cytoplasmic Membrane
J. Biol. Chem. 2005 280: 637-643. First Published on November 2, 2004; doi:10.1074/jbc.M411247200 [Abstract] [Full Text] [PDF]  

Kyoung Joon Oh, Scott Barbuto, Natalie Meyer, Ryung-Suk Kim, R. John Collier, and Stanley J. Korsmeyer
Conformational Changes in BID, a Pro-apoptotic BCL-2 Family Member, upon Membrane Binding: A SITE-DIRECTED SPIN LABELING STUDY
J. Biol. Chem. 2005 280: 753-767. First Published on October 21, 2004; doi:10.1074/jbc.M405428200 [Abstract] [Full Text] [PDF]  

Wendy R. Mathews, Fudi Wang, David J. Eide, and Mark Van Doren
Drosophila fear of intimacy Encodes a Zrt/IRT-like Protein (ZIP) Family Zinc Transporter Functionally Related to Mammalian ZIP Proteins
J. Biol. Chem. 2005 280: 787-795. First Published on October 27, 2004; doi:10.1074/jbc.M411308200 [Abstract] [Full Text] [PDF]  

Olga A. Akimova, Alexei Y. Bagrov, Olga D. Lopina, Alexey V. Kamernitsky, Johanne Tremblay, Pavel Hamet, and Sergei N. Orlov
Cardiotonic Steroids Differentially Affect Intracellular Na+ and [Na+]i/[K+]i-independent Signaling in C7-MDCK Cells
J. Biol. Chem. 2005 280: 832-839. First Published on October 19, 2004; doi:10.1074/jbc.M411011200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Guoliang Qing, Zhaoxia Qu, and Gutian Xiao
Regulation of NF-{kappa}B2 p100 Processing by Its cis-Acting Domain
J. Biol. Chem. 2005 280: 18-27. First Published on October 14, 2004; doi:10.1074/jbc.M406619200 [Abstract] [Full Text] [PDF]  

Kim N. Robinson, Kara Manto, Rachel J. Buchsbaum, James I. S. MacDonald, and Susan O. Meakin
Neurotrophin-dependent Tyrosine Phosphorylation of Ras Guanine-releasing Factor 1 and Associated Neurite Outgrowth Is Dependent on the HIKE Domain of TrkA
J. Biol. Chem. 2005 280: 225-235. First Published on October 28, 2004; doi:10.1074/jbc.M410454200 [Abstract] [Full Text] [PDF]  

Kazuhiro Maeta, Shingo Izawa, and Yoshiharu Inoue
Methylglyoxal, a Metabolite Derived from Glycolysis, Functions as a Signal Initiator of the High Osmolarity Glycerol-Mitogen-activated Protein Kinase Cascade and Calcineurin/Crz1-mediated Pathway in Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 253-260. First Published on November 1, 2004; doi:10.1074/jbc.M408061200 [Abstract] [Full Text] [PDF]  

William H. Stoothoff, Jae-Hyeon Cho, Roy P. McDonald, and Gail V. W. Johnson
FRAT-2 Preferentially Increases Glycogen Synthase Kinase 3{beta}-mediated Phosphorylation of Primed Sites, Which Results in Enhanced Tau Phosphorylation
J. Biol. Chem. 2005 280: 270-276. First Published on November 1, 2004; doi:10.1074/jbc.M410061200 [Abstract] [Full Text] [PDF]  

Ezra Aksoy, Claudia S. Zouain, François Vanhoutte, Josette Fontaine, Norman Pavelka, Nathalie Thieblemont, Fabienne Willems, Paola Ricciardi-Castagnoli, Michel Goldman, Monique Capron, Bernard Ryffel, and François Trottein
Double-stranded RNAs from the Helminth Parasite Schistosoma Activate TLR3 in Dendritic Cells
J. Biol. Chem. 2005 280: 277-283. First Published on November 1, 2004; doi:10.1074/jbc.M411223200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Yuqi Wang, Louis A. Marotti, Jr., Michael J. Lee, and Henrik G. Dohlman
Differential Regulation of G Protein {alpha} Subunit Trafficking by Mono- and Polyubiquitination
J. Biol. Chem. 2005 280: 284-291. First Published on November 1, 2004; doi:10.1074/jbc.M411624200 [Abstract] [Full Text] [PDF]  

Sangwook Jung, Myles H. Akabas, and R. Adron Harris
Functional and Structural Analysis of the GABAA Receptor {alpha}1 Subunit during Channel Gating and Alcohol Modulation
J. Biol. Chem. 2005 280: 308-316. First Published on November 2, 2004; doi:10.1074/jbc.M409871200 [Abstract] [Full Text] [PDF]  

Vijaykumar R. Holla, Dingzhi Wang, Joanne R. Brown, Jason R. Mann, Sharada Katkuri, and Raymond N. DuBois
Prostaglandin E2 Regulates the Complement Inhibitor CD55/Decay-accelerating Factor in Colorectal Cancer
J. Biol. Chem. 2005 280: 476-483. First Published on November 1, 2004; doi:10.1074/jbc.M407403200 [Abstract] [Full Text] [PDF]  

Ahmed Chahdi, Bradley Miller, and Andrey Sorokin
Endothelin 1 Induces {beta}1Pix Translocation and Cdc42 Activation via Protein Kinase A-dependent Pathway
J. Biol. Chem. 2005 280: 578-584. First Published on October 28, 2004; doi:10.1074/jbc.M411130200 [Abstract] [Full Text] [PDF]  

Charito S. Buensuceso, Achim Obergfell, Alessandra Soriani, Koji Eto, William B. Kiosses, Elena G. Arias-Salgado, Toshiaki Kawakami, and Sanford J. Shattil
Regulation of Outside-in Signaling in Platelets by Integrin-associated Protein Kinase C{beta}
J. Biol. Chem. 2005 280: 644-653. First Published on November 9, 2004; doi:10.1074/jbc.M410229200 [Abstract] [Full Text] [PDF]  

Jean-Christophe Corvol, Emmanuel Valjent, Madeleine Toutant, Hervé Enslen, Théano Irinopoulou, Sima Lev, Denis Hervé, and Jean-Antoine Girault
Depolarization Activates ERK and Proline-rich Tyrosine Kinase 2 (PYK2) Independently in Different Cellular Compartments in Hippocampal Slices
J. Biol. Chem. 2005 280: 660-668. First Published on November 10, 2004; doi:10.1074/jbc.M411312200 [Abstract] [Full Text] [PDF]  

Joshua J. Martindale, Jason A. Wall, Diana M. Martinez-Longoria, Prafulla Aryal, Howard A. Rockman, Yiru Guo, Roberto Bolli, and Christopher C. Glembotski
Overexpression of Mitogen-activated Protein Kinase Kinase 6 in the Heart Improves Functional Recovery from Ischemia in Vitro and Protects against Myocardial Infarction in Vivo
J. Biol. Chem. 2005 280: 669-676. First Published on October 18, 2004; doi:10.1074/jbc.M406690200 [Abstract] [Full Text] [PDF]  

Yoshimi Endo, Vladimir Wolf, Kanae Muraiso, Keiju Kamijo, Lilian Soon, Aykut Üren, Michal Barshishat-Küpper, and Jeffrey S. Rubin
Wnt-3a-dependent Cell Motility Involves RhoA Activation and Is Specifically Regulated by Dishevelled-2
J. Biol. Chem. 2005 280: 777-786. First Published on October 27, 2004; doi:10.1074/jbc.M406391200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Hyeseon Cho, Dong-Uk Kim, and John H. Kehrl
RGS14 Is a Centrosomal and Nuclear Cytoplasmic Shuttling Protein That Traffics to Promyelocytic Leukemia Nuclear Bodies Following Heat Shock
J. Biol. Chem. 2005 280: 805-814. First Published on November 1, 2004; doi:10.1074/jbc.M408163200 [Abstract] [Full Text] [PDF]  

Takashi Futami, Makoto Miyagishi, and Kazunari Taira
Identification of a Network Involved in Thapsigargin-induced Apoptosis Using a Library of Small Interfering RNA Expression Vectors
J. Biol. Chem. 2005 280: 826-831. First Published on October 14, 2004; doi:10.1074/jbc.M409948200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Yoshihisa Nakatani, Hideaki Kaneto, Dan Kawamori, Kazutomi Yoshiuchi, Masahiro Hatazaki, Taka-aki Matsuoka, Kentaro Ozawa, Satoshi Ogawa, Masatsugu Hori, Yoshimitsu Yamasaki, and Munehide Matsuhisa
Involvement of Endoplasmic Reticulum Stress in Insulin Resistance and Diabetes
J. Biol. Chem. 2005 280: 847-851. First Published on October 27, 2004; doi:10.1074/jbc.M411860200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Naohiko Koshikawa, Tomoko Minegishi, Andrew Sharabi, Vito Quaranta, and Motoharu Seiki
Membrane-type Matrix Metalloproteinase-1 (MT1-MMP) Is a Processing Enzyme for Human Laminin {gamma}2 Chain
J. Biol. Chem. 2005 280: 88-93. First Published on November 3, 2004; doi:10.1074/jbc.M411824200 [Abstract] [Full Text] [PDF]  

Mike Lee, Margono Hadi, Gunnel Halldén, and Gregory W. Aponte
Peptide YY and Neuropeptide Y Induce Villin Expression, Reduce Adhesion, and Enhance Migration in Small Intestinal Cells through the Regulation of CD63, Matrix Metalloproteinase-3, and Cdc42 Activity
J. Biol. Chem. 2005 280: 125-136. First Published on October 25, 2004; doi:10.1074/jbc.M408858200 [Abstract] [Full Text] [PDF]  

Changlu Liu, Chester Kuei, Steven Sutton, Jingcai Chen, Pascal Bonaventure, Jiejun Wu, Diane Nepomuceno, Fredrik Kamme, Da-Thao Tran, Jessica Zhu, Tracey Wilkinson, Ross Bathgate, Elo Eriste, Rannar Sillard, and Timothy W. Lovenberg
INSL5 Is a High Affinity Specific Agonist for GPCR142 (GPR100)
J. Biol. Chem. 2005 280: 292-300. First Published on November 2, 2004; doi:10.1074/jbc.M409916200 [Abstract] [Full Text] [PDF]  

Hasan N. Rajabi, Sudhakar Baluchamy, Sivanagarani Kolli, Alo Nag, Rampalli Srinivas, Pradip Raychaudhuri, and Bayar Thimmapaya
Effects of Depletion of CREB-binding Protein on c-Myc Regulation and Cell Cycle G1-S Transition
J. Biol. Chem. 2005 280: 361-374. First Published on November 2, 2004; doi:10.1074/jbc.M408633200 [Abstract] [Full Text] [PDF]  

Shuangsong Hong and John W. Wiley
Early Painful Diabetic Neuropathy Is Associated with Differential Changes in the Expression and Function of Vanilloid Receptor 1
J. Biol. Chem. 2005 280: 618-627. First Published on October 27, 2004; doi:10.1074/jbc.M408500200 [Abstract] [Full Text] [PDF]  

Zhibo Yang, Ratna K. Vadlamudi, and Rakesh Kumar
Dynein Light Chain 1 Phosphorylation Controls Macropinocytosis
J. Biol. Chem. 2005 280: 654-659. First Published on October 24, 2004; doi:10.1074/jbc.M408486200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Sadayappan Sakthivel, Natosha L. Finley, Paul R. Rosevear, John N. Lorenz, James Gulick, Scott Kim, Peter VanBuren, Lisa A. Martin, and Jeffrey Robbins
In Vivo and in Vitro Analysis of Cardiac Troponin I Phosphorylation
J. Biol. Chem. 2005 280: 703-714. First Published on October 26, 2004; doi:10.1074/jbc.M409513200 [Abstract] [Full Text] [PDF]  

Christopher J. Nelsen, Ryoko Kuriyama, Betsy Hirsch, Vivian C. Negron, Wilma L. Lingle, Melissa M. Goggin, Michael W. Stanley, and Jeffrey H. Albrecht
Short Term Cyclin D1 Overexpression Induces Centrosome Amplification, Mitotic Spindle Abnormalities, and Aneuploidy
J. Biol. Chem. 2005 280: 768-776. First Published on October 26, 2004; doi:10.1074/jbc.M407105200 [Abstract] [Full Text] [PDF]  

Taihei Fukuyama, Hisakazu Ogita, Tomomi Kawakatsu, Tatsuro Fukuhara, Tomohiro Yamada, Tatsuhiro Sato, Kazuya Shimizu, Takeshi Nakamura, Michiyuki Matsuda, and Yoshimi Takai
Involvement of the c-Src-Crk-C3G-Rap1 Signaling in the Nectin-induced Activation of Cdc42 and Formation of Adherens Junctions
J. Biol. Chem. 2005 280: 815-825. First Published on October 25, 2004; doi:10.1074/jbc.M411099200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Zheng Li and Christina Chan
Integrating gene expression and metabolic profiles. Vol. 279 (2004) 27124-27137
J. Biol. Chem. 2005 280: 852. [Full Text] [PDF]  


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