JBC Focus on PI3-Kinase with Echelon

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Table of Contents: Mar 18 2005; 280 (11)   [Index by Author]  [Papers Of The Week]
[Cover Figure and Caption]
      Down Papers Of The Week
      Down Reflections
      Down Classics
      Down Accelerated Publications
      Down DNA: Replication, Repair, and Recombination
      Down Genes: Structure and Regulation
      Down Protein Synthesis, Post-Translation Modification, and Degradation
      Down Genomics, Proteomics, and Bioinformatics
      Down Protein Structure and Folding
      Down Enzyme Catalysis and Regulation
      Down Metabolism and Bioenergetics
      Down Glycobiology and Extracellular Matrices
      Down Lipids and Lipoproteins
      Down Membrane Transport, Structure, Function, and Biogenesis
      Down Mechanisms Of Signal Transduction
      Down Molecular Basis Of Cell and Developmental Biology
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Papers Of The Week:Back

A New Player in Septic Shock
J. Biol. Chem. 2005 280: e99910. [Full Text] [PDF]  

Enzyme Resurrection
J. Biol. Chem. 2005 280: e99911. [Full Text] [PDF]  


Reflections:Back

George R. Stark
My Life in Science, Not the Restaurant Business
J. Biol. Chem. 2005 280: 9753-9760. First Published on January 4, 2005; doi:10.1074/jbc.X400011200 [Full Text] [PDF]  


Classics:Back

Nicole Kresge, Robert D. Simoni, and Robert L. Hill
Severo Ochoa's Contributions to the Citric Acid Cycle
ENZYMATIC SYNTHESIS OF CITRIC ACID. I. SYNTHESIS WITH SOLUBLE ENZYMES (Joseph R. Stern and Severo Ochoa J. Biol. Chem. 191, 161-172)
ENZYMATIC SYNTHESIS OF CITRIC ACID. IV. PYRUVATE AS ACETYL DONOR (Seymour Korkes, Alice del Campillo, I. C. Gunsalus, and Severo Ochoa J. Biol. Chem. 193, 721-735)
J. Biol. Chem. 2005 280: e8. [Full Text]  


Accelerated Publications:Back

Rabindranath Ray, Moonsuk Choi, Zhongjian Zhang, Gary A. Silverman, David Askew, and Anil B. Mukherjee
Uteroglobin Suppresses SCCA Gene Expression Associated with Allergic Asthma
J. Biol. Chem. 2005 280: 9761-9764. First Published on January 27, 2005; doi:10.1074/jbc.C400581200 [Abstract] [Full Text] [PDF]  

Guoliang Qing and Gutian Xiao
Essential Role of I{kappa}B Kinase {alpha} in the Constitutive Processing of NF-{kappa}B2 p100
J. Biol. Chem. 2005 280: 9765-9768. First Published on January 27, 2005; doi:10.1074/jbc.C400502200 [Abstract] [Full Text] [PDF]  

Michael N. Corradetti, Ken Inoki, and Kun-Liang Guan
The Stress-inducted Proteins RTP801 and RTP801L Are Negative Regulators of the Mammalian Target of Rapamycin Pathway
J. Biol. Chem. 2005 280: 9769-9772. First Published on January 4, 2005; doi:10.1074/jbc.C400557200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:Back

Zhenya Li, Jennifer L. Kitchen, Kelly Boeneman, Priyanka Anand, and Elliott Crooke
Restoration of Growth to Acidic Phospholipid-deficient Cells by DnaA(L366K) Is Independent of Its Capacity for Nucleotide Binding and Exchange and Requires DnaA
J. Biol. Chem. 2005 280: 9796-9801. First Published on January 10, 2005; doi:10.1074/jbc.M413923200 [Abstract] [Full Text] [PDF]  

Jelena Kusic, Snezana Kojic, Aleksandra Divac, and Dragana Stefanovic
Noncanonical DNA Elements in the Lamin B2 Origin of DNA Replication
J. Biol. Chem. 2005 280: 9848-9854. First Published on December 19, 2004; doi:10.1074/jbc.M408310200 [Abstract] [Full Text] [PDF]  

Michele Giannattasio, Federico Lazzaro, Paolo Plevani, and Marco Muzi-Falconi
The DNA Damage Checkpoint Response Requires Histone H2B Ubiquitination by Rad6-Bre1 and H3 Methylation by Dot1
J. Biol. Chem. 2005 280: 9879-9886. First Published on January 4, 2005; doi:10.1074/jbc.M414453200 [Abstract] [Full Text] [PDF]  

Alan J. Tackett, Yingfeng Chen, Craig E. Cameron, and Kevin D. Raney
Multiple Full-length NS3 Molecules Are Required for Optimal Unwinding of Oligonucleotide DNA in Vitro
J. Biol. Chem. 2005 280: 10797-10806. First Published on January 4, 2005; doi:10.1074/jbc.M407971200 [Abstract] [Full Text] [PDF]  

Jozef Nosek, Adriana Rycovska, Alexander M. Makhov, Jack D. Griffith, and Lubomir Tomaska
Amplification of Telomeric Arrays via Rolling-circle Mechanism
J. Biol. Chem. 2005 280: 10840-10845. First Published on January 18, 2005; doi:10.1074/jbc.M409295200 [Abstract] [Full Text] [PDF]  

Branden Wolner and Craig L. Peterson
ATP-dependent and ATP-independent Roles for the Rad54 Chromatin Remodeling Enzyme during Recombinational Repair of a DNA Double Strand Break
J. Biol. Chem. 2005 280: 10855-10860. First Published on January 14, 2005; doi:10.1074/jbc.M414388200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:Back

Michaël Boyer-Guittaut, Kivanç Birsoy, Corinne Potel, Gill Elliott, Ellis Jaffray, Joanna M. Desterro, Ron T. Hay, and Thomas Oelgeschläger
SUMO-1 Modification of Human Transcription Factor (TF) IID Complex Subunits: INHIBITION OF TFIID PROMOTER-BINDING ACTIVITY THROUGH SUMO-1 MODIFICATION OF hsTAF5
J. Biol. Chem. 2005 280: 9937-9945. First Published on January 6, 2005; doi:10.1074/jbc.M414149200 [Abstract] [Full Text] [PDF]  

Hancheng Guan, Shihe Hou, and Robert P. Ricciardi
DNA Binding of Repressor Nuclear Factor-{kappa}B p50/p50 Depends on Phosphorylation of Ser337 by the Protein Kinase A Catalytic Subunit
J. Biol. Chem. 2005 280: 9957-9962. First Published on January 7, 2005; doi:10.1074/jbc.M412180200 [Abstract] [Full Text] [PDF]  

Weiqi Huang, Shujie Zhao, Sudhakar Ammanamanchi, Michael Brattain, Kolaparthi Venkatasubbarao, and James W. Freeman
Trichostatin A Induces Transforming Growth Factor {beta} Type II Receptor Promoter Activity and Acetylation of Sp1 by Recruitment of PCAF/p300 to a Sp1·NF-Y Complex
J. Biol. Chem. 2005 280: 10047-10054. First Published on January 12, 2005; doi:10.1074/jbc.M408680200 [Abstract] [Full Text] [PDF]  

Soo-Jin Jeong, Cynthia A. Pise-Masison, Michael F. Radonovich, Hyeon Ung Park, and John N. Brady
A Novel NF-{kappa}B Pathway Involving IKK{beta} and p65/RelA Ser-536 Phosphorylation Results in p53 Inhibition in the Absence of NF-{kappa}B Transcriptional Activity
J. Biol. Chem. 2005 280: 10326-10332. First Published on December 20, 2004; doi:10.1074/jbc.M412643200 [Abstract] [Full Text] [PDF]  

Jae B. Park and Mark Levine
Cloning, Sequencing, and Characterization of Alternatively Spliced Glutaredoxin 1 cDNA and Its Genomic Gene: CHROMOSOMAL LOCALIZATION, mRNA STABILITY, AND ORIGIN OF PSEUDOGENES
J. Biol. Chem. 2005 280: 10427-10434. First Published on January 6, 2005; doi:10.1074/jbc.M412450200 [Abstract] [Full Text] [PDF]  

Thomas Hiesberger, Xinli Shao, Eric Gourley, Andreas Reimann, Marco Pontoglio, and Peter Igarashi
Role of the Hepatocyte Nuclear Factor-1{beta} (HNF-1{beta}) C-terminal Domain in Pkhd1 (ARPKD) Gene Transcription and Renal Cystogenesis
J. Biol. Chem. 2005 280: 10578-10586. First Published on January 12, 2005; doi:10.1074/jbc.M414121200 [Abstract] [Full Text] [PDF]  

María J. L. Barragán, Blas Blázquez, María T. Zamarro, José M. Mancheño, José L. García, Eduardo Díaz, and Manuel Carmona
BzdR, a Repressor That Controls the Anaerobic Catabolism of Benzoate in Azoarcus sp. CIB, Is the First Member of a New Subfamily of Transcriptional Regulators
J. Biol. Chem. 2005 280: 10683-10694. First Published on January 5, 2005; doi:10.1074/jbc.M412259200 [Abstract] [Full Text] [PDF]  

Xuefeng Liu, Hang Yuan, Baojin Fu, Gary L. Disbrow, Tania Apolinario, Vjekoslav Tomaic, Melissa L. Kelley, Carl C. Baker, Jon Huibregtse, and Richard Schlegel
The E6AP Ubiquitin Ligase Is Required for Transactivation of the hTERT Promoter by the Human Papillomavirus E6 Oncoprotein
J. Biol. Chem. 2005 280: 10807-10816. First Published on January 17, 2005; doi:10.1074/jbc.M410343200 [Abstract] [Full Text] [PDF]  

Greg L. Mayeur, Wei-Jen Kung, Anthony Martinez, Chie Izumiya, David J. Chen, and Hsing-Jien Kung
Ku Is a Novel Transcriptional Recycling Coactivator of the Androgen Receptor in Prostate Cancer Cells
J. Biol. Chem. 2005 280: 10827-10833. First Published on January 7, 2005; doi:10.1074/jbc.M413336200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:Back

Gil Blander, Jerzy Olejnik, Edyta Krzymanska-Olejnik, Thomas McDonagh, Marcia Haigis, Michael B. Yaffe, and Leonard Guarente
SIRT1 Shows No Substrate Specificity in Vitro
J. Biol. Chem. 2005 280: 9780-9785. First Published on January 6, 2005; doi:10.1074/jbc.M414080200 [Abstract] [Full Text] [PDF]  

Benjamin S. Rayner, Ben-Jing Wu, Mark Raftery, Roland Stocker, and Paul K. Witting
Human S-Nitroso Oxymyoglobin Is a Store of Vasoactive Nitric Oxide
J. Biol. Chem. 2005 280: 9985-9993. First Published on January 10, 2005; doi:10.1074/jbc.M410564200 [Abstract] [Full Text] [PDF]  

Paul Cohen, Guoqing Yang, Xinxin Yu, Alexander A. Soukas, Cara S. Wolfish, Jeffrey M. Friedman, and Cai Li
Induction of Leptin Receptor Expression in the Liver by Leptin and Food Deprivation
J. Biol. Chem. 2005 280: 10034-10039. First Published on January 11, 2005; doi:10.1074/jbc.M413684200 [Abstract] [Full Text] [PDF]  

Chih-Sheng Yang, Chenchou Yu, Hsiao-Ching Chuang, Ching-Wen Chang, Geen-Dong Chang, Tso-Pang Yao, and Hungwen Chen
FBW2 Targets GCMa to the Ubiquitin-Proteasome Degradation System
J. Biol. Chem. 2005 280: 10083-10090. First Published on January 8, 2005; doi:10.1074/jbc.M413986200 [Abstract] [Full Text] [PDF]  

Hiroshi Ohkawara, Toshiyuki Ishibashi, Takayuki Sakamoto, Koichi Sugimoto, Kenji Nagata, Keiko Yokoyama, Nobuo Sakamoto, Masashi Kamioka, Isao Matsuoka, Shigetomo Fukuhara, Naotoshi Sugimoto, Yoh Takuwa, and Yukio Maruyama
Thrombin-induced Rapid Geranylgeranylation of RhoA as an Essential Process for RhoA Activation in Endothelial Cells
J. Biol. Chem. 2005 280: 10182-10188. First Published on January 7, 2005; doi:10.1074/jbc.M409547200 [Abstract] [Full Text] [PDF]  

Kazunori Watanabe, Osamu Nureki, Shuya Fukai, Ryohei Ishii, Hironori Okamoto, Shigeyuki Yokoyama, Yaeta Endo, and Hiroyuki Hori
Roles of Conserved Amino Acid Sequence Motifs in the SpoU (TrmH) RNA Methyltransferase Family
J. Biol. Chem. 2005 280: 10368-10377. First Published on January 6, 2005; doi:10.1074/jbc.M411209200 [Abstract] [Full Text] [PDF]  

Joyce Rubotham, Katherine Woods, Jose A. Garcia-Salcedo, Etienne Pays, and Derek P. Nolan
Characterization of Two Protein Disulfide Isomerases from the Endocytic Pathway of Bloodstream Forms of Trypanosoma brucei
J. Biol. Chem. 2005 280: 10410-10418. First Published on January 10, 2005; doi:10.1074/jbc.M409375200 [Abstract] [Full Text] [PDF]  

Nadeem Wajih, David C. Sane, Susan M. Hutson, and Reidar Wallin
Engineering of a Recombinant Vitamin K-dependent {gamma}-Carboxylation System with Enhanced {gamma}-Carboxyglutamic Acid Forming Capacity: EVIDENCE FOR A FUNCTIONAL CXXC REDOX CENTER IN THE SYSTEM
J. Biol. Chem. 2005 280: 10540-10547. First Published on January 7, 2005; doi:10.1074/jbc.M413982200 [Abstract] [Full Text] [PDF]  

Yoshitaka Nobukuni, Kenji Kohno, and Kiyoshi Miyagawa
Gene Trap Mutagenesis-based Forward Genetic Approach Reveals That the Tumor Suppressor OVCA1 Is a Component of the Biosynthetic Pathway of Diphthamide on Elongation Factor 2
J. Biol. Chem. 2005 280: 10572-10577. First Published on January 5, 2005; doi:10.1074/jbc.M413017200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:Back

Mythily Srinivasan, Debao Lu, Rajaraman Eri, David D. Brand, Azizul Haque, and Janice S. Blum
CD80 Binding Polyproline Helical Peptide Inhibits T Cell Activation
J. Biol. Chem. 2005 280: 10149-10155. First Published on December 14, 2004; doi:10.1074/jbc.M409521200 [Abstract] [Full Text] [PDF]  

Fiana Levitin, Amos Baruch, Mordechai Weiss, Keren Stiegman, Mor-li Hartmann, Merav Yoeli-Lerner, Ravit Ziv, Sheila Zrihan-Licht, Sima Shina, Andrea Gat, Beatrice Lifschitz, Moshe Simha, Yona Stadler, Alina Cholostoy, Benny Gil, David Greaves, Iafa Keydar, Joseph Zaretsky, Nechama Smorodinsky, and Daniel H. Wreschner
A Novel Protein Derived from the MUC1 Gene by Alternative Splicing and Frameshifting
J. Biol. Chem. 2005 280: 10655-10663. First Published on December 28, 2004; doi:10.1074/jbc.M406943200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:Back

Avelina Fernandez Garcia, Philipp Heindl, Heiner Voigt, Mathias Büttner, Peter Butz, Nora Tauber, Bernhard Tauscher, and Eberhard Pfaff
Dual Nature of the Infectious Prion Protein Revealed by High Pressure
J. Biol. Chem. 2005 280: 9842-9847. First Published on December 13, 2004; doi:10.1074/jbc.M410679200 [Abstract] [Full Text] [PDF]  

Hazel Tapp, Iman M. Al-Naggar, Elena G. Yarmola, Alexis Harrison, Gerry Shaw, Arthur S. Edison, and Michael R. Bubb
MARCKS Is a Natively Unfolded Protein with an Inaccessible Actin-binding Site: EVIDENCE FOR LONG-RANGE INTRAMOLECULAR INTERACTIONS
J. Biol. Chem. 2005 280: 9946-9956. First Published on January 6, 2005; doi:10.1074/jbc.M414614200 [Abstract] [Full Text] [PDF]  

Sandra Oesterreicher, Werner F. Blum, Bernhard Schmidt, Thomas Braulke, and Bernd Kübler
Interaction of Insulin-like Growth Factor II (IGF-II) with Multiple Plasma Proteins: HIGH AFFINITY BINDING OF PLASMINOGEN TO IGF-II AND IGF-BINDING PROTEIN-3
J. Biol. Chem. 2005 280: 9994-10000. First Published on January 10, 2005; doi:10.1074/jbc.M411754200 [Abstract] [Full Text] [PDF]  

Vesa P. Hytönen, Juha A. E. Määttä, Thomas K. M. Nyholm, Oded Livnah, Yael Eisenberg-Domovich, David Hyre, Henri R. Nordlund, Jarno Hörhä, Einari A. Niskanen, Tiina Paldanius, Tuomas Kulomaa, Eevaleena J. Porkka, Patrick S. Stayton, Olli H. Laitinen, and Markku S. Kulomaa
Design and Construction of Highly Stable, Protease-resistant Chimeric Avidins
J. Biol. Chem. 2005 280: 10228-10233. First Published on January 13, 2005; doi:10.1074/jbc.M414196200 [Abstract] [Full Text] [PDF]  

Günter Brader, Solveig Sjöblom, Heidi Hyytiäinen, Karen Sims-Huopaniemi, and E. Tapio Palva
Altering Substrate Chain Length Specificity of an Acylhomoserine Lactone Synthase in Bacterial Communication
J. Biol. Chem. 2005 280: 10403-10409. First Published on January 5, 2005; doi:10.1074/jbc.M408603200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Zhongliang Zhu, Zhi Liang, Tianyi Zhang, Zhiqiang Zhu, Weihua Xu, Maikun Teng, and Liwen Niu
Crystal Structures and Amidolytic Activities of Two Glycosylated Snake Venom Serine Proteinases
J. Biol. Chem. 2005 280: 10524-10529. First Published on January 4, 2005; doi:10.1074/jbc.M412900200 [Abstract] [Full Text] [PDF]  

Min-Hsuan Chen, Iris Ben-Efraim, Gregory Mitrousis, Nancy Walker-Kopp, Peter J. Sims, and Gino Cingolani
Phospholipid Scramblase 1 Contains a Nonclassical Nuclear Localization Signal with Unique Binding Site in Importin {alpha}
J. Biol. Chem. 2005 280: 10599-10606. First Published on December 17, 2004; doi:10.1074/jbc.M413194200 [Abstract] [Full Text] [PDF]  

Giulia Calloni, Sara Zoffoli, Massimo Stefani, Christopher M. Dobson, and Fabrizio Chiti
Investigating the Effects of Mutations on Protein Aggregation in the Cell
J. Biol. Chem. 2005 280: 10607-10613. First Published on December 16, 2004; doi:10.1074/jbc.M412951200 [Abstract] [Full Text] [PDF] [Supplemental data]  

Maria E. Carrizo, Stefano Capaldi, Massimiliano Perduca, Fernando J. Irazoqui, Gustavo A. Nores, and Hugo L. Monaco
The Antineoplastic Lectin of the Common Edible Mushroom (Agaricus bisporus) Has Two Binding Sites, Each Specific for a Different Configuration at a Single Epimeric Hydroxyl
J. Biol. Chem. 2005 280: 10614-10623. First Published on December 13, 2004; doi:10.1074/jbc.M411989200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Janice Bramham, Chuong-Thu Thai, Dinesh C. Soares, Dusan Uhrín, Ronald T. Ogata, and Paul N. Barlow
Functional Insights from the Structure of the Multifunctional C345C Domain of C5 of Complement
J. Biol. Chem. 2005 280: 10636-10645. First Published on December 14, 2004; doi:10.1074/jbc.M413126200 [Abstract] [Full Text] [PDF]  

Winco W. H. Wu, Julie P. Wong, Juergen Kast, and Robert S. Molday
RS1, a Discoidin Domain-containing Retinal Cell Adhesion Protein Associated with X-linked Retinoschisis, Exists as a Novel Disulfide-linked Octamer
J. Biol. Chem. 2005 280: 10721-10730. First Published on January 11, 2005; doi:10.1074/jbc.M413117200 [Abstract] [Full Text] [PDF]  

Andrea Gorrell, Sarah H. Lawrence, and James G. Ferry
Structural and Kinetic Analyses of Arginine Residues in the Active Site of the Acetate Kinase from Methanosarcina thermophila
J. Biol. Chem. 2005 280: 10731-10742. First Published on January 12, 2005; doi:10.1074/jbc.M412118200 [Abstract] [Full Text] [PDF]  

Nelson P. Barrera, Susan J. Ormond, Robert M. Henderson, Ruth D. Murrell-Lagnado, and J. Michael Edwardson
Atomic Force Microscopy Imaging Demonstrates that P2X2 Receptors Are Trimers but That P2X6 Receptor Subunits Do Not Oligomerize
J. Biol. Chem. 2005 280: 10759-10765. First Published on January 18, 2005; doi:10.1074/jbc.M412265200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:Back

Simon Glerup, Henning B. Boldt, Michael T. Overgaard, Lars Sottrup-Jensen, Linda C. Giudice, and Claus Oxvig
Proteinase Inhibition by Proform of Eosinophil Major Basic Protein (pro-MBP) Is a Multistep Process of Intra- and Intermolecular Disulfide Rearrangements
J. Biol. Chem. 2005 280: 9823-9832. First Published on January 12, 2005; doi:10.1074/jbc.M413228200 [Abstract] [Full Text] [PDF]  

Sergio C. Chai, Ann A. Jerkins, Jacob J. Banik, Ilia Shalev, Jennifer L. Pinkham, Peter C. Uden, and Michael J. Maroney
Heterologous Expression, Purification, and Characterization of Recombinant Rat Cysteine Dioxygenase
J. Biol. Chem. 2005 280: 9865-9869. First Published on December 28, 2004; doi:10.1074/jbc.M413733200 [Abstract] [Full Text] [PDF]  

Amanpreet Kambo, Vijay S. Sharma, Darren E. Casteel, Virgil L. Woods, Jr., Renate B. Pilz, and Gerry R. Boss
Nitric Oxide Inhibits Mammalian Methylmalonyl-CoA Mutase
J. Biol. Chem. 2005 280: 10073-10082. First Published on January 12, 2005; doi:10.1074/jbc.M411842200 [Abstract] [Full Text] [PDF]  

Miguel A. Ballicora, Jennifer R. Dubay, Claire H. Devillers, and Jack Preiss
Resurrecting the Ancestral Enzymatic Role of a Modulatory Subunit
J. Biol. Chem. 2005 280: 10189-10195. First Published on January 4, 2005; doi:10.1074/jbc.M413540200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]  

Wei-Hsiung Yang and Stephen R Hammes
Xenopus laevis CYP17 Regulates Androgen Biosynthesis Independent of the Cofactor Cytochrome b5
J. Biol. Chem. 2005 280: 10196-10201. First Published on January 7, 2005; doi:10.1074/jbc.M411886200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Seiya Watanabe, Tsutomu Kodaki, and Keisuke Makino
Complete Reversal of Coenzyme Specificity of Xylitol Dehydrogenase and Increase of Thermostability by the Introduction of Structural Zinc
J. Biol. Chem. 2005 280: 10340-10349. First Published on December 28, 2004; doi:10.1074/jbc.M409443200 [Abstract] [Full Text] [PDF]  

Takashi Yanagawa, Tatsuyoshi Funasaka, Soichi Tsutsumi, Tirza Raz, Nobutada Tanaka, and Avraham Raz
Differential Regulation of Phosphoglucose Isomerase/Autocrine Motility Factor Activities by Protein Kinase CK2 Phosphorylation
J. Biol. Chem. 2005 280: 10419-10426. First Published on January 5, 2005; doi:10.1074/jbc.M409457200 [Abstract] [Full Text] [PDF]  

Jin Na Shin, Young Woo Seo, Moonil Kim, Sun-Young Park, Mi-Ja Lee, Byung Rai Lee, Jae-Wook Oh, Dai-Wu Seol, and Tae-Hyoung Kim
Cisplatin Inactivation of Caspases Inhibits Death Ligand-induced Cell Death in Vitro and Fulminant Liver Damage in Mice
J. Biol. Chem. 2005 280: 10509-10515. First Published on January 5, 2005; doi:10.1074/jbc.M413865200 [Abstract] [Full Text] [PDF]  

Hanan Latif Messiha, Andrew W. Munro, Neil C. Bruce, Igor Barsukov, and Nigel S. Scrutton
Reaction of Morphinone Reductase with 2-Cyclohexen-1-one and 1-Nitrocyclohexene: PROTON DONATION, LIGAND BINDING, AND THE ROLE OF RESIDUES HISTIDINE 186 AND ASPARAGINE 189
J. Biol. Chem. 2005 280: 10695-10709. First Published on January 4, 2005; doi:10.1074/jbc.M410595200 [Abstract] [Full Text] [PDF]  

Nicole M. Koropatkin, W. Wallace Cleland, and Hazel M. Holden
Kinetic and Structural Analysis of {alpha}-D-Glucose-1-phosphate Cytidylyltransferase from Salmonella typhi
J. Biol. Chem. 2005 280: 10774-10780. First Published on January 5, 2005; doi:10.1074/jbc.M414111200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Rekha G. Panchal, Kelly M. Halverson, Wilson Ribot, Douglas Lane, Tara Kenny, Teresa G. Abshire, John W. Ezzell, Timothy A. Hoover, Bradford Powell, Stephen Little, John J. Kasianowicz, and Sina Bavari
Purified Bacillus anthracis Lethal Toxin Complex Formed in Vitro and during Infection Exhibits Functional and Biological Activity
J. Biol. Chem. 2005 280: 10834-10839. First Published on January 11, 2005; doi:10.1074/jbc.M412210200 [Abstract] [Full Text] [PDF]  

In Sup Kil and Jeen-Woo Park
Regulation of Mitochondrial NADP+-dependent Isocitrate Dehydrogenase Activity by Glutathionylation
J. Biol. Chem. 2005 280: 10846-10854. First Published on January 14, 2005; doi:10.1074/jbc.M411306200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:Back

Tien-Shin Yu, Samuel C. Zeeman, David Thorneycroft, Daniel C. Fulton, Hannah Dunstan, Wei-Ling Lue, Björn Hegemann, Shu-Yun Tung, Takayuki Umemoto, Andrew Chapple, Der-Long Tsai, Shue-Mei Wang, Alison M. Smith, Jychian Chen, and Steven M. Smith
{alpha}-Amylase Is Not Required for Breakdown of Transitory Starch in Arabidopsis Leaves
J. Biol. Chem. 2005 280: 9773-9779. First Published on January 6, 2005; doi:10.1074/jbc.M413638200 [Abstract] [Full Text] [PDF]  

Seung Y. Park, Guem H. Choi, Hyo I. Choi, Jiwon Ryu, Chan Y. Jung, and Wan Lee
Depletion of Mitochondrial DNA Causes Impaired Glucose Utilization and Insulin Resistance in L6 GLUT4myc Myocytes
J. Biol. Chem. 2005 280: 9855-9864. First Published on December 17, 2004; doi:10.1074/jbc.M409399200 [Abstract] [Full Text] [PDF]  

Vincent Corvest, Claude Sigalat, Renée Venard, Pierre Falson, David M. Mueller, and Francis Haraux
The Binding Mechanism of the Yeast F1-ATPase Inhibitory Peptide: ROLE OF CATALYTIC INTERMEDIATES AND ENZYME TURNOVER
J. Biol. Chem. 2005 280: 9927-9936. First Published on January 6, 2005; doi:10.1074/jbc.M414098200 [Abstract] [Full Text] [PDF]  

Janet Flatley, Jason Barrett, Steven T. Pullan, Martin N. Hughes, Jeffrey Green, and Robert K. Poole
Transcriptional Responses of Escherichia coli to S-Nitrosoglutathione under Defined Chemostat Conditions Reveal Major Changes in Methionine Biosynthesis
J. Biol. Chem. 2005 280: 10065-10072. First Published on January 12, 2005; doi:10.1074/jbc.M410393200 [Abstract] [Full Text] [PDF]  

Julian C. Rutherford, Luis Ojeda, Janneke Balk, Ulrich Mühlenhoff, Roland Lill, and Dennis R. Winge
Activation of the Iron Regulon by the Yeast Aft1/Aft2 Transcription Factors Depends on Mitochondrial but Not Cytosolic Iron-Sulfur Protein Biogenesis
J. Biol. Chem. 2005 280: 10135-10140. First Published on January 13, 2005; doi:10.1074/jbc.M413731200 [Abstract] [Full Text] [PDF]  

Dawn K. Richardson, Sangeeta Kashyap, Mandeep Bajaj, Kenneth Cusi, Steven J. Mandarino, Jean Finlayson, Ralph A. DeFronzo, Christopher P. Jenkinson, and Lawrence J. Mandarino
Lipid Infusion Decreases the Expression of Nuclear Encoded Mitochondrial Genes and Increases the Expression of Extracellular Matrix Genes in Human Skeletal Muscle
J. Biol. Chem. 2005 280: 10290-10297. First Published on December 14, 2004; doi:10.1074/jbc.M408985200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Matthew E. Nelson, Giovanni Finazzi, Qing Jun Wang, Kelly A. Middleton-Zarka, John Whitmarsh, and Toivo Kallas
Cytochrome b6 Arginine 214 of Synechococcus sp. PCC 7002, a Key Residue for Quinone-reductase Site Function and Turnover of the Cytochrome bf Complex
J. Biol. Chem. 2005 280: 10395-10402. First Published on January 4, 2005; doi:10.1074/jbc.M410948200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:Back

Leena Heiska and Olli Carpén
Src Phosphorylates Ezrin at Tyrosine 477 and Induces a Phosphospecific Association between Ezrin and a Kelch-Repeat Protein Family Member
J. Biol. Chem. 2005 280: 10244-10252. First Published on December 28, 2004; doi:10.1074/jbc.M411353200 [Abstract] [Full Text] [PDF]  

Agnès Barret, Lionel Forestier, Jean-Philippe Deslys, Raymond Julien, and Paul François Gallet
Glycosylation-related Gene Expression in Prion Diseases: PrPSc ACCUMULATION IN SCRAPIE INFECTED GT1 CELLS DEPENDS ON {beta}-1,4-LINKED GalNAc-4-SO4 HYPOSULFATION
J. Biol. Chem. 2005 280: 10516-10523. First Published on January 4, 2005; doi:10.1074/jbc.M412635200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:Back

Veerle Foulon, Mieke Sniekers, Els Huysmans, Stanny Asselberghs, Vincent Mahieu, Guy P. Mannaerts, Paul P. Van Veldhoven, and Minne Casteels
Breakdown of 2-Hydroxylated Straight Chain Fatty Acids via Peroxisomal 2-Hydroxyphytanoyl-CoA Lyase: A REVISED PATHWAY FOR THE {alpha}-OXIDATION OF STRAIGHT CHAIN FATTY ACIDS
J. Biol. Chem. 2005 280: 9802-9812. First Published on January 11, 2005; doi:10.1074/jbc.M413362200 [Abstract] [Full Text] [PDF]  

Mohammad Reza Hojjati, Zhiqiang Li, Hongwen Zhou, Songshan Tang, Chongmin Huan, Everlyn Ooi, Shendi Lu, and Xian-Cheng Jiang
Effect of Myriocin on Plasma Sphingolipid Metabolism and Atherosclerosis in apoE-deficient Mice
J. Biol. Chem. 2005 280: 10284-10289. First Published on December 6, 2004; doi:10.1074/jbc.M412348200 [Abstract] [Full Text] [PDF]  

Jessica Passeggio and Laura Liscum
Flux of Fatty Acids through NPC1 Lysosomes
J. Biol. Chem. 2005 280: 10333-10339. First Published on January 4, 2005; doi:10.1074/jbc.M413657200 [Abstract] [Full Text] [PDF]  

Niv Papo and Yechiel Shai
A Molecular Mechanism for Lipopolysaccharide Protection of Gram-negative Bacteria from Antimicrobial Peptides
J. Biol. Chem. 2005 280: 10378-10387. First Published on January 4, 2005; doi:10.1074/jbc.M412865200 [Abstract] [Full Text] [PDF]  

Joseph R. Marszalek, Claire Kitidis, Concetta C. DiRusso, and Harvey F. Lodish
Long-chain Acyl-CoA Synthetase 6 Preferentially Promotes DHA Metabolism
J. Biol. Chem. 2005 280: 10817-10826. First Published on January 17, 2005; doi:10.1074/jbc.M411750200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:Back

Yong Jiang, Hiranmoy Bhattacharjee, Tongqing Zhou, Barry P. Rosen, Suresh V. Ambudkar, and Zuben E. Sauna
Nonequivalence of the Nucleotide Binding Domains of the ArsA ATPase
J. Biol. Chem. 2005 280: 9921-9926. First Published on January 6, 2005; doi:10.1074/jbc.M413391200 [Abstract] [Full Text] [PDF]  

Koji Yamano, Daigo Ishikawa, Masatoshi Esaki, and Toshiya Endo
The Phosphate Carrier Has an Ability to be Sorted to either the TIM22 Pathway or the TIM23 Pathway for Its Import into Yeast Mitochondria
J. Biol. Chem. 2005 280: 10011-10017. First Published on January 11, 2005; doi:10.1074/jbc.M413264200 [Abstract] [Full Text] [PDF]  

Wakako Shimoi, Ichiko Ezawa, Koji Nakamoto, Shihoko Uesaki, Gavin Gabreski, Meir Aridor, Akitsugu Yamamoto, Masami Nagahama, Mitsuo Tagaya, and Katsuko Tani
p125 Is Localized in Endoplasmic Reticulum Exit Sites and Involved in Their Organization
J. Biol. Chem. 2005 280: 10141-10148. First Published on December 28, 2004; doi:10.1074/jbc.M409673200 [Abstract] [Full Text] [PDF]  

Eugenia G. Politis, Amy F. Roth, and Nicholas G. Davis
Transmembrane Topology of the Protein Palmitoyl Transferase Akr1
J. Biol. Chem. 2005 280: 10156-10163. First Published on January 4, 2005; doi:10.1074/jbc.M411946200 [Abstract] [Full Text] [PDF]  

Mads Toustrup-Jensen and Bente Vilsen
Interaction between the Catalytic Site and the A-M3 Linker Stabilizes E2/E2P Conformational States of Na+,K+-ATPase
J. Biol. Chem. 2005 280: 10210-10218. First Published on November 30, 2004; doi:10.1074/jbc.M411214200 [Abstract] [Full Text] [PDF]  

Aija Kyttälä, Kristiina Yliannala, Peter Schu, Anu Jalanko, and J. Paul Luzio
AP-1 and AP-3 Facilitate Lysosomal Targeting of Batten Disease Protein CLN3 via Its Dileucine Motif
J. Biol. Chem. 2005 280: 10277-10283. First Published on December 13, 2004; doi:10.1074/jbc.M411862200 [Abstract] [Full Text] [PDF]  

Hideyuki Kobayashi, Nobuyuki Tanaka, Hironobu Asao, Shigeto Miura, Masanao Kyuuma, Kayoko Semura, Nobuhisa Ishii, and Kazuo Sugamura
Hrs, a Mammalian Master Molecule in Vesicular Transport and Protein Sorting, Suppresses the Degradation of ESCRT Proteins Signal Transducing Adaptor Molecule 1 and 2
J. Biol. Chem. 2005 280: 10468-10477. First Published on January 7, 2005; doi:10.1074/jbc.M409969200 [Abstract] [Full Text] [PDF]  

Rachael Z. Murray, Fiona G. Wylie, Tatiana Khromykh, David A. Hume, and Jennifer L. Stow
Syntaxin 6 and Vti1b Form a Novel SNARE Complex, Which Is Up-regulated in Activated Macrophages to Facilitate Exocytosis of Tumor Necrosis Factor-{alpha}
J. Biol. Chem. 2005 280: 10478-10483. First Published on January 7, 2005; doi:10.1074/jbc.M414420200 [Abstract] [Full Text] [PDF]  

Kelly M. Weixel, Anna Blumental-Perry, Simon C. Watkins, Meir Aridor, and Ora A. Weisz
Distinct Golgi Populations of Phosphatidylinositol 4-Phosphate Regulated by Phosphatidylinositol 4-Kinases
J. Biol. Chem. 2005 280: 10501-10508. First Published on January 5, 2005; doi:10.1074/jbc.M414304200 [Abstract] [Full Text] [PDF]  

Zhenhui Chen, David L. Stokes, and Larry R. Jones
Role of Leucine 31 of Phospholamban in Structural and Functional Interactions with the Ca2+ Pump of Cardiac Sarcoplasmic Reticulum
J. Biol. Chem. 2005 280: 10530-10539. First Published on January 10, 2005; doi:10.1074/jbc.M414007200 [Abstract] [Full Text] [PDF]  

Diane McVey Ward, Michael B. Vaughn, Shelly L. Shiflett, Paul L. White, Amanda L. Pollock, Joshua Hill, Rachel Schnegelberger, Wesley I. Sundquist, and Jerry Kaplan
The Role of LIP5 and CHMP5 in Multivesicular Body Formation and HIV-1 Budding in Mammalian Cells
J. Biol. Chem. 2005 280: 10548-10555. First Published on January 11, 2005; doi:10.1074/jbc.M413734200 [Abstract] [Full Text] [PDF]  

Julian Thimm, Adam Mechler, Hai Lin, Seung Rhee, and Ratnesh Lal
Calcium-dependent Open/Closed Conformations and Interfacial Energy Maps of Reconstituted Hemichannels
J. Biol. Chem. 2005 280: 10646-10654. First Published on December 21, 2004; doi:10.1074/jbc.M412749200 [Abstract] [Full Text] [PDF]  

Hualin Zhong, Akiko Takeda, Reza Nazari, Helen Shio, Günter Blobel, and Nabeel R. Yaseen
Carrier-independent Nuclear Import of the Transcription Factor PU.1 via RanGTP-stimulated Binding to Nup153
J. Biol. Chem. 2005 280: 10675-10682. First Published on January 4, 2005; doi:10.1074/jbc.M412878200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:Back

Ifeanyi J. Arinze and Yumiko Kawai
Transcriptional Activation of the Human G{alpha}i2 Gene Promoter through Nuclear Factor-{kappa}B and Antioxidant Response Elements
J. Biol. Chem. 2005 280: 9786-9795. First Published on January 7, 2005; doi:10.1074/jbc.M414006200 [Abstract] [Full Text] [PDF]  

Dominic De Nardo, Paul Masendycz, Sokwei Ho, Maddalena Cross, Andrew J. Fleetwood, Eric C. Reynolds, John A. Hamilton, and Glen M. Scholz
A Central Role for the Hsp90·Cdc37 Molecular Chaperone Module in Interleukin-1 Receptor-associated-kinase-dependent Signaling by Toll-like Receptors
J. Biol. Chem. 2005 280: 9813-9822. First Published on January 12, 2005; doi:10.1074/jbc.M409745200 [Abstract] [Full Text] [PDF]  

Michael D. Davis, Jeremy J. Clemens, Timothy L. Macdonald, and Kevin R. Lynch
Sphingosine 1-Phosphate Analogs as Receptor Antagonists
J. Biol. Chem. 2005 280: 9833-9841. First Published on December 8, 2004; doi:10.1074/jbc.M412356200 [Abstract] [Full Text] [PDF]  

Jürgen van Baal, John de Widt, Nullin Divecha, and Wim J. van Blitterswijk
Translocation of Diacylglycerol Kinase {theta} from Cytosol to Plasma Membrane in Response to Activation of G Protein-coupled Receptors and Protein Kinase C
J. Biol. Chem. 2005 280: 9870-9878. First Published on January 4, 2005; doi:10.1074/jbc.M409301200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Jörn M. Schattenberg, Yongjun Wang, Rajat Singh, Raina M. Rigoli, and Mark J. Czaja
Hepatocyte CYP2E1 Overexpression and Steatohepatitis Lead to Impaired Hepatic Insulin Signaling
J. Biol. Chem. 2005 280: 9887-9894. First Published on January 4, 2005; doi:10.1074/jbc.M410310200 [Abstract] [Full Text] [PDF]  

Yann Percherancier, Yamina A. Berchiche, Isabelle Slight, Rudolf Volkmer-Engert, Hirokazu Tamamura, Nobutaka Fujii, Michel Bouvier, and Nikolaus Heveker
Bioluminescence Resonance Energy Transfer Reveals Ligand-induced Conformational Changes in CXCR4 Homo- and Heterodimers
J. Biol. Chem. 2005 280: 9895-9903. First Published on January 4, 2005; doi:10.1074/jbc.M411151200 [Abstract] [Full Text] [PDF]  

Paul-Eduard Neagoe, Caroline Lemieux, and Martin G. Sirois
Vascular Endothelial Growth Factor (VEGF)-A165-induced Prostacyclin Synthesis Requires the Activation of VEGF Receptor-1 and -2 Heterodimer
J. Biol. Chem. 2005 280: 9904-9912. First Published on January 6, 2005; doi:10.1074/jbc.M412017200 [Abstract] [Full Text] [PDF]  

Jian Cui, Marina Holgado-Madruga, Wanwen Su, Hiromasa Tsuiki, Philip Wedegaertner, and Albert J. Wong
Identification of a Specific Domain Responsible for JNK2{alpha}2 Autophosphorylation
J. Biol. Chem. 2005 280: 9913-9920. First Published on January 6, 2005; doi:10.1074/jbc.M412165200 [Abstract] [Full Text] [PDF]  

Hee Yun, Minyoung Lee, Sung-Soo Kim, and Joohun Ha
Glucose Deprivation Increases mRNA Stability of Vascular Endothelial Growth Factor through Activation of AMP-activated Protein Kinase in DU145 Prostate Carcinoma
J. Biol. Chem. 2005 280: 9963-9972. First Published on January 7, 2005; doi:10.1074/jbc.M412994200 [Abstract] [Full Text] [PDF]  

Michael H. Pillinger, Nada Marjanovic, Seok-Yong Kim, Jose U. Scher, Peter Izmirly, Sonia Tolani, Victoria Dinsell, Yong-Chan Lee, Martin J. Blaser, and Steven B. Abramson
Matrix Metalloproteinase Secretion by Gastric Epithelial Cells Is Regulated by E Prostaglandins and MAPKs
J. Biol. Chem. 2005 280: 9973-9979. First Published on January 7, 2005; doi:10.1074/jbc.M413522200 [Abstract] [Full Text] [PDF]  

Antonio Rodríguez, Sara Martínez-Martínez, Ma Dolores López-Maderuelo, Inmaculada Ortega-Pérez, and Juan Miguel Redondo
The Linker Region Joining the Catalytic and the Regulatory Domains of CnA Is Essential for Binding to NFAT
J. Biol. Chem. 2005 280: 9980-9984. First Published on January 25, 2005; doi:10.1074/jbc.C400401200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Yongzhong Li, Sandeep Batra, Antonella Sassano, Beata Majchrzak, David E. Levy, Matthias Gaestel, Eleanor N. Fish, Roger J. Davis, and Leonidas C. Platanias
Activation of Mitogen-activated Protein Kinase Kinase (MKK) 3 and MKK6 by Type I Interferons
J. Biol. Chem. 2005 280: 10001-10010. First Published on January 11, 2005; doi:10.1074/jbc.M410972200 [Abstract] [Full Text] [PDF]  

Matthew D. Morrison, William Reiley, Minying Zhang, and Shao-Cong Sun
An Atypical Tumor Necrosis Factor (TNF) Receptor-associated Factor-binding Motif of B Cell-activating Factor Belonging to the TNF Family (BAFF) Receptor Mediates Induction of the Noncanonical NF-{kappa}B Signaling Pathway
J. Biol. Chem. 2005 280: 10018-10024. First Published on January 11, 2005; doi:10.1074/jbc.M413634200 [Abstract] [Full Text] [PDF]  

Edwin Bremer, Douwe F. Samplonius, Linda van Genne, Marike H. Dijkstra, Bart Jan Kroesen, Lou F. M. H. de Leij, and Wijnand Helfrich
Simultaneous Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling and Enhanced Activation of Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Receptor-mediated Apoptosis Induction by an scFv:sTRAIL Fusion Protein with Specificity for Human EGFR
J. Biol. Chem. 2005 280: 10025-10033. First Published on January 11, 2005; doi:10.1074/jbc.M413673200 [Abstract] [Full Text] [PDF]  

Linda Connelly, Melanie Madhani, and Adrian J. Hobbs
Resistance to Endotoxic Shock in Endothelial Nitric-oxide Synthase (eNOS) Knock-out Mice: A PRO-INFLAMMATORY ROLE FOR eNOS-DERIVED NO IN VIVO
J. Biol. Chem. 2005 280: 10040-10046. First Published on January 12, 2005; doi:10.1074/jbc.M411991200 [Abstract] [Full Text] [PDF] [Summary]  

Shigeki Tsukada, John K. Westwick, Kenichi Ikejima, Nobuhiro Sato, and Richard A. Rippe
SMAD and p38 MAPK Signaling Pathways Independently Regulate {alpha}1(I) Collagen Gene Expression in Unstimulated and Transforming Growth Factor-{beta}-stimulated Hepatic Stellate Cells
J. Biol. Chem. 2005 280: 10055-10064. First Published on January 12, 2005; doi:10.1074/jbc.M409381200 [Abstract] [Full Text] [PDF]  

Antonia Ávila-Flores, Teresa Santos, Esther Rincón, and Isabel Mérida
Modulation of the Mammalian Target of Rapamycin Pathway by Diacylglycerol Kinase-produced Phosphatidic Acid
J. Biol. Chem. 2005 280: 10091-10099. First Published on January 4, 2005; doi:10.1074/jbc.M412296200 [Abstract] [Full Text] [PDF]  

Olivia S. Gardner, Chung-Wai Shiau, Ching-Shih Chen, and Lee M. Graves
Peroxisome Proliferator-activated Receptor {gamma}-independent Activation of p38 MAPK by Thiazolidinediones Involves Calcium/Calmodulin-dependent Protein Kinase II and Protein Kinase R: CORRELATION WITH ENDOPLASMIC RETICULUM STRESS
J. Biol. Chem. 2005 280: 10109-10118. First Published on January 13, 2005; doi:10.1074/jbc.M410445200 [Abstract] [Full Text] [PDF]  

Che-Chang Chang, Ding-Yen Lin, Hsin-I Fang, Ruey-Hwa Chen, and Hsiu-Ming Shih
Daxx Mediates the Small Ubiquitin-like Modifier-dependent Transcriptional Repression of Smad4
J. Biol. Chem. 2005 280: 10164-10173. First Published on January 6, 2005; doi:10.1074/jbc.M409161200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Tabetha M. Bonacci, Mousumi Ghosh, Sundeep Malik, and Alan V. Smrcka
Regulatory Interactions between the Amino Terminus of G-protein {beta}{gamma} Subunits and the Catalytic Domain of Phospholipase C{beta}2
J. Biol. Chem. 2005 280: 10174-10181. First Published on December 16, 2004; doi:10.1074/jbc.M412514200 [Abstract] [Full Text] [PDF]  

Carla M. Pedrosa Ribeiro, Anthony M. Paradiso, Mark A. Carew, Stephen B. Shears, and Richard C. Boucher
Cystic Fibrosis Airway Epithelial Ca2+i Signaling: THE MECHANISM FOR THE LARGER AGONIST-MEDIATED Ca2+i SIGNALS IN HUMAN CYSTIC FIBROSIS AIRWAY EPITHELIA
J. Biol. Chem. 2005 280: 10202-10209. First Published on January 12, 2005; doi:10.1074/jbc.M410617200 [Abstract] [Full Text] [PDF]  

Amélie Perron, Philippe Sarret, Louis Gendron, Thomas Stroh, and Alain Beaudet
Identification and Functional Characterization of a 5-Transmembrane Domain Variant Isoform of the NTS2 Neurotensin Receptor in Rat Central Nervous System
J. Biol. Chem. 2005 280: 10219-10227. First Published on January 6, 2005; doi:10.1074/jbc.M410557200 [Abstract] [Full Text] [PDF]  

Jonathan D. Humphries, Neil R. Schofield, Zohreh Mostafavi-Pour, Linda J. Green, Alistair N. Garratt, A. Paul Mould, and Martin J. Humphries
Dual Functionality of the Anti-{beta}1 Integrin Antibody, 12G10, Exemplifies Agonistic Signalling from the Ligand Binding Pocket of Integrin Adhesion Receptors
J. Biol. Chem. 2005 280: 10234-10243. First Published on January 4, 2005; doi:10.1074/jbc.M411102200 [Abstract] [Full Text] [PDF]  

Paul A. Bromann, Hasan Korkaya, Craig P. Webb, Jeremy Miller, Tammy L. Calvin, and Sara A. Courtneidge
Platelet-derived Growth Factor Stimulates Src-dependent mRNA Stabilization of Specific Early Genes in Fibroblasts
J. Biol. Chem. 2005 280: 10253-10263. First Published on January 5, 2005; doi:10.1074/jbc.M413806200 [Abstract] [Full Text] [PDF]  

Arnoud Groen, Simone Lemeer, Thea van der Wijk, John Overvoorde, Albert J. R. Heck, Arne Ostman, David Barford, Monique Slijper, and Jeroen den Hertog
Differential Oxidation of Protein-tyrosine Phosphatases
J. Biol. Chem. 2005 280: 10298-10304. First Published on December 28, 2004; doi:10.1074/jbc.M412424200 [Abstract] [Full Text] [PDF]  

Miwako Iwai, Yoko Tateishi, Mitsuharu Hattori, Akihiro Mizutani, Takeshi Nakamura, Akira Futatsugi, Takafumi Inoue, Teiichi Furuichi, Takayuki Michikawa, and Katsuhiko Mikoshiba
Molecular Cloning of Mouse Type 2 and Type 3 Inositol 1,4,5-Trisphosphate Receptors and Identification of a Novel Type 2 Receptor Splice Variant
J. Biol. Chem. 2005 280: 10305-10317. First Published on January 4, 2005; doi:10.1074/jbc.M413824200 [Abstract] [Full Text] [PDF]  

Pamela J. Woodring, Tony Hunter, and Jean Y. J. Wang
Mitotic Phosphorylation Rescues Abl from F-actin-mediated Inhibition
J. Biol. Chem. 2005 280: 10318-10325. First Published on January 4, 2005; doi:10.1074/jbc.M410658200 [Abstract] [Full Text] [PDF]  

Vijay K. Yadav, Garimella Lakshmi, and Rudraiah Medhamurthy
Prostaglandin F2{alpha}-mediated Activation of Apoptotic Signaling Cascades in the Corpus Luteum during Apoptosis: INVOLVEMENT OF CASPASE-ACTIVATED DNase
J. Biol. Chem. 2005 280: 10357-10367. First Published on December 28, 2004; doi:10.1074/jbc.M409596200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Shane Bruckner, Souad Rhamouni, Lutz Tautz, Jean-Bernard Denault, Andres Alonso, Barbara Becattini, Guy S. Salvesen, and Tomas Mustelin
Yersinia Phosphatase Induces Mitochondrially Dependent Apoptosis of T Cells
J. Biol. Chem. 2005 280: 10388-10394. First Published on January 4, 2005; doi:10.1074/jbc.M408829200 [Abstract] [Full Text] [PDF]  

Weiping Zheng, Dirk Schwarzer, Aaron LeBeau, Joan L. Weller, David C. Klein, and Philip A. Cole
Cellular Stability of Serotonin N-Acetyltransferase Conferred by Phosphonodifluoromethylene Alanine (Pfa) Substitution for Ser-205
J. Biol. Chem. 2005 280: 10462-10467. First Published on January 4, 2005; doi:10.1074/jbc.M412283200 [Abstract] [Full Text] [PDF]  

Eric Gumpricht, Rolf Dahl, Michael W. Devereaux, and Ronald J. Sokol
Licorice Compounds Glycyrrhizin and 18{beta}-Glycyrrhetinic Acid Are Potent Modulators of Bile Acid-induced Cytotoxicity in Rat Hepatocytes
J. Biol. Chem. 2005 280: 10556-10563. First Published on January 10, 2005; doi:10.1074/jbc.M411673200 [Abstract] [Full Text] [PDF]  

Hongbin Li, Xiaoqin Ye, Chitladda Mahanivong, Dafang Bian, Jerold Chun, and Shuang Huang
Signaling Mechanisms Responsible for Lysophosphatidic Acid-induced Urokinase Plasminogen Activator Expression in Ovarian Cancer Cells
J. Biol. Chem. 2005 280: 10564-10571. First Published on January 14, 2005; doi:10.1074/jbc.M412152200 [Abstract] [Full Text] [PDF]  

Hua Zhou and Randall H. Kramer
Integrin Engagement Differentially Modulates Epithelial Cell Motility by RhoA/ROCK and PAK1
J. Biol. Chem. 2005 280: 10624-10635. First Published on December 17, 2004; doi:10.1074/jbc.M411900200 [Abstract] [Full Text] [PDF]  

Elodie Archer-Lahlou, Chantal Escrieut, Pascal Clerc, Jean Martinez, Luis Moroder, Craig Logsdon, Alan Kopin, Catherine Seva, Marlène Dufresne, Lucien Pradayrol, Bernard Maigret, and Daniel Fourmy
Molecular Mechanism Underlying Partial and Full Agonism Mediated by the Human Cholecystokinin-1 Receptor
J. Biol. Chem. 2005 280: 10664-10674. First Published on January 4, 2005; doi:10.1074/jbc.M409451200 [Abstract] [Full Text] [PDF]  

Audrey Ferrand, Aline Kowalski-Chauvel, Claudine Bertrand, Chantal Escrieut, Anne Mathieu, Ghislaine Portolan, Lucien Pradayrol, Daniel Fourmy, Marlene Dufresne, and Catherine Seva
A Novel Mechanism for JAK2 Activation by a G Protein-coupled Receptor, the CCK2R: IMPLICATION OF THIS SIGNALING PATHWAY IN PANCREATIC TUMOR MODELS
J. Biol. Chem. 2005 280: 10710-10715. First Published on January 7, 2005; doi:10.1074/jbc.M413309200 [Abstract] [Full Text] [PDF]  

Guozhi Zhu, Koichi Fujii, Natalya Belkina, Yin Liu, Michael James, Juan Herrero, and Stephen Shaw
Exceptional Disfavor for Proline at the P+1 Position among AGC and CAMK Kinases Establishes Reciprocal Specificity between Them and the Proline-directed Kinases
J. Biol. Chem. 2005 280: 10743-10748. First Published on January 12, 2005; doi:10.1074/jbc.M413159200 [Abstract] [Full Text] [PDF]  

Espen E. Spangenburg
SOCS-3 Induces Myoblast Differentiation
J. Biol. Chem. 2005 280: 10749-10758. First Published on January 14, 2005; doi:10.1074/jbc.M410604200 [Abstract] [Full Text] [PDF]  

Meiguo Xin and Xingming Deng
Nicotine Inactivation of the Proapoptotic Function of Bax through Phosphorylation
J. Biol. Chem. 2005 280: 10781-10789. First Published on January 10, 2005; doi:10.1074/jbc.M500084200 [Abstract] [Full Text] [PDF]  

Elisa Babilonia, Yuan Wei, Hyacinth Sterling, Pawel Kaminski, Michael Wolin, and Wen-Hui Wang
Superoxide Anions Are Involved in Mediating the Effect of Low K Intake on c-Src Expression and Renal K Secretion in the Cortical Collecting Duct
J. Biol. Chem. 2005 280: 10790-10796. First Published on January 11, 2005; doi:10.1074/jbc.M414610200 [Abstract] [Full Text] [PDF]  

Jae Youn Yi, Incheol Shin, and Carlos L. Arteaga
Type I Transforming Growth Factor {beta} Receptor Binds to and Activates Phosphatidylinositol 3-Kinase
J. Biol. Chem. 2005 280: 10870-10876. First Published on January 18, 2005; doi:10.1074/jbc.M413223200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:Back

Kimberley M. Dorval, Brian P. Bobechko, K. Farid Ahmad, and Rod Bremner
Transcriptional Activity of the Paired-like Homeodomain Proteins CHX10 and VSX1
J. Biol. Chem. 2005 280: 10100-10108. First Published on January 12, 2005; doi:10.1074/jbc.M412676200 [Abstract] [Full Text] [PDF]  

He Huang, Mojgan Rastegar, Caroline Bodner, Siew-Lee Goh, Isabel Rambaldi, and Mark Featherstone
MEIS C Termini Harbor Transcriptional Activation Domains That Respond to Cell Signaling
J. Biol. Chem. 2005 280: 10119-10127. First Published on January 15, 2005; doi:10.1074/jbc.M413963200 [Abstract] [Full Text] [PDF]  

Nobutaka Saeki, Hiroshi Tokuo, and Mitsuo Ikebe
BIG1 Is a Binding Partner of Myosin IXb and Regulates Its Rho-GTPase Activating Protein Activity
J. Biol. Chem. 2005 280: 10128-10134. First Published on January 11, 2005; doi:10.1074/jbc.M413415200 [Abstract] [Full Text] [PDF]  

Toula Bouras, Maofu Fu, Anthony A. Sauve, Fang Wang, Andrew A. Quong, Neil D. Perkins, Ronald T. Hay, Wei Gu, and Richard G. Pestell
SIRT1 Deacetylation and Repression of p300 Involves Lysine Residues 1020/1024 within the Cell Cycle Regulatory Domain 1
J. Biol. Chem. 2005 280: 10264-10276. First Published on January 4, 2005; doi:10.1074/jbc.M408748200 [Abstract] [Full Text] [PDF]  

Petros Petrou, Evangelos Pavlakis, Yannis Dalezios, Vassilis K. Galanopoulos, and Georges Chalepakis
Basement Membrane Distortions Impair Lung Lobation and Capillary Organization in the Mouse Model for Fraser Syndrome
J. Biol. Chem. 2005 280: 10350-10356. First Published on December 28, 2004; doi:10.1074/jbc.M412368200 [Abstract] [Full Text] [PDF]  

Iris Müller, Ninon Subert, Heike Otto, Rosa Herbst, Harald Rühling, Markus Maniak, and Matthias Leippe
A Dictyostelium Mutant with Reduced Lysozyme Levels Compensates by Increased Phagocytic Activity
J. Biol. Chem. 2005 280: 10435-10443. First Published on January 7, 2005; doi:10.1074/jbc.M411445200 [Abstract] [Full Text] [PDF]  

Hideyuki Takeuchi, Tetsuya Mizuno, Guiqin Zhang, Jinyan Wang, Jun Kawanokuchi, Reiko Kuno, and Akio Suzumura
Neuritic Beading Induced by Activated Microglia Is an Early Feature of Neuronal Dysfunction Toward Neuronal Death by Inhibition of Mitochondrial Respiration and Axonal Transport
J. Biol. Chem. 2005 280: 10444-10454. First Published on January 7, 2005; doi:10.1074/jbc.M413863200 [Abstract] [Full Text] [PDF]  

Quynh T. Phan, Rutillio A. Fratti, Nemani V. Prasadarao, John E. Edwards, Jr., and Scott G. Filler
N-cadherin Mediates Endocytosis of Candida albicans by Endothelial Cells
J. Biol. Chem. 2005 280: 10455-10461. First Published on January 4, 2005; doi:10.1074/jbc.M412592200 [Abstract] [Full Text] [PDF]  

Jonathan H. Lieman, Lori A. Worley, and J. William Harbour
Loss of Rb-E2F Repression Results in Caspase-8-mediated Apoptosis through Inactivation of Focal Adhesion Kinase
J. Biol. Chem. 2005 280: 10484-10490. First Published on January 7, 2005; doi:10.1074/jbc.M409371200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Changjiang Weng, Yuan Li, Dan Xu, Yong Shi, and Hong Tang
Specific Cleavage of Mcl-1 by Caspase-3 in Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis in Jurkat Leukemia T Cells
J. Biol. Chem. 2005 280: 10491-10500. First Published on January 6, 2005; doi:10.1074/jbc.M412819200 [Abstract] [Full Text] [PDF]  

Pierre-François Cartron, Hubert Arokium, Lisa Oliver, Khaled Meflah, Stephen Manon, and François M. Vallette
Distinct Domains Control the Addressing and the Insertion of Bax into Mitochondria
J. Biol. Chem. 2005 280: 10587-10598. First Published on December 7, 2004; doi:10.1074/jbc.M409714200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Ali M. Riazi, Haeyul Lee, Christina Hsu, and Glen Van Arsdell
CSX/Nkx2.5 Modulates Differentiation of Skeletal Myoblasts and Promotes Differentiation into Neuronal Cells in Vitro
J. Biol. Chem. 2005 280: 10716-10720. First Published on January 13, 2005; doi:10.1074/jbc.M500028200 [Abstract] [Full Text] [PDF]  

Yuzhi Jia, Chao Qi, Zhongyi Zhang, Yiwei Tony Zhu, Sambasiva M. Rao, and Yi-Jun Zhu
Peroxisome Proliferator-activated Receptor-binding Protein Null Mutation Results in Defective Mammary Gland Development
J. Biol. Chem. 2005 280: 10766-10773. First Published on January 12, 2005; doi:10.1074/jbc.M413331200 [Abstract] [Full Text] [PDF]  

Jiliang Zhou and B. Paul Herring
Mechanisms Responsible for the Promoter-specific Effects of Myocardin
J. Biol. Chem. 2005 280: 10861-10869. First Published on January 17, 2005; doi:10.1074/jbc.M411586200 [Abstract] [Full Text] [PDF]  


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